CN1191851C - 包含胆碱结合蛋白an-末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用 - Google Patents

包含胆碱结合蛋白an-末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用 Download PDF

Info

Publication number
CN1191851C
CN1191851C CNB998108545A CN99810854A CN1191851C CN 1191851 C CN1191851 C CN 1191851C CN B998108545 A CNB998108545 A CN B998108545A CN 99810854 A CN99810854 A CN 99810854A CN 1191851 C CN1191851 C CN 1191851C
Authority
CN
China
Prior art keywords
lys
glu
polypeptide
ala
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998108545A
Other languages
English (en)
Chinese (zh)
Other versions
CN1342088A (zh
Inventor
E·I·托曼恩
H·R·马舒尔
T·M·维泽曼
L·S·约翰逊
S·科尼格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Childrens Research Hospital
MedImmune LLC
Original Assignee
St Jude Childrens Research Hospital
MedImmune LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/056,019 external-priority patent/US6858706B2/en
Application filed by St Jude Childrens Research Hospital, MedImmune LLC filed Critical St Jude Childrens Research Hospital
Publication of CN1342088A publication Critical patent/CN1342088A/zh
Application granted granted Critical
Publication of CN1191851C publication Critical patent/CN1191851C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB998108545A 1998-04-07 1999-04-07 包含胆碱结合蛋白an-末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用 Expired - Fee Related CN1191851C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US09/056,019 US6858706B2 (en) 1998-04-07 1998-04-07 Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US60/080,878 1998-04-07
US09/056,019 1998-04-07

Publications (2)

Publication Number Publication Date
CN1342088A CN1342088A (zh) 2002-03-27
CN1191851C true CN1191851C (zh) 2005-03-09

Family

ID=26734874

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998108545A Expired - Fee Related CN1191851C (zh) 1998-04-07 1999-04-07 包含胆碱结合蛋白an-末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用

Country Status (14)

Country Link
JP (1) JP4739521B2 (enExample)
KR (1) KR100638503B1 (enExample)
CN (1) CN1191851C (enExample)
AU (2) AU3479699A (enExample)
BR (1) BR9909910A (enExample)
CA (1) CA2326388C (enExample)
HU (1) HUP0102306A3 (enExample)
IL (1) IL138939A0 (enExample)
MX (1) MXPA00009899A (enExample)
NO (1) NO20005081L (enExample)
NZ (1) NZ507983A (enExample)
PL (1) PL193132B1 (enExample)
TR (1) TR200003498T2 (enExample)
WO (1) WO1999051188A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
CA2808919C (en) 2005-12-22 2016-04-19 Glaxosmithkline Biologicals S.A. Streptococcus pneumoniae capsular saccharide vaccine
KR101579947B1 (ko) 2007-06-26 2015-12-28 글락소스미스클라인 바이오로지칼즈 에스.에이. 스트렙토코쿠스 뉴모니애 캡슐 다당류 컨쥬게이트를 포함하는 백신
WO2009127676A1 (en) 2008-04-16 2009-10-22 Glaxosmithkline Biologicals S.A. Vaccine
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
AU2012257771C1 (en) 2011-05-17 2015-12-03 Glaxosmithkline Biologicals S.A. Vaccine against Streptococcus pneumoniae
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
WO1997041151A2 (en) * 1996-05-01 1997-11-06 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
DE69739981D1 (de) * 1996-10-31 2010-10-14 Human Genome Sciences Inc Streptococcus pneumoniae-Antigene und Impfstoffe
AU5355398A (en) * 1996-11-12 1998-06-03 Regents Of The University Of Minnesota C3 binding protein of (streptococcus pneumoniae)
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
DE69942176D1 (de) * 1998-04-07 2010-05-06 Medimmune Llc Choline-bindende proteine derivate aus pneumokoken als impfstoff

Also Published As

Publication number Publication date
AU3479699A (en) 1999-10-25
NZ507983A (en) 2004-03-26
KR100638503B1 (ko) 2006-10-26
BR9909910A (pt) 2002-01-15
WO1999051188A9 (en) 2000-10-12
HUP0102306A3 (en) 2008-04-28
CA2326388C (en) 2014-02-04
NO20005081D0 (no) 2000-10-09
CN1342088A (zh) 2002-03-27
PL193132B1 (pl) 2007-01-31
CA2326388A1 (en) 1999-10-14
AU3479799A (en) 1999-10-25
HUP0102306A1 (hu) 2001-09-28
NO20005081L (no) 2000-12-06
MXPA00009899A (es) 2002-05-08
PL347946A1 (en) 2002-04-22
IL138939A0 (en) 2001-11-25
TR200003498T2 (tr) 2001-10-22
AU764811B2 (en) 2003-08-28
KR20010052244A (ko) 2001-06-25
WO1999051188A3 (en) 2001-04-19
JP4739521B2 (ja) 2011-08-03
WO1999051188A2 (en) 1999-10-14
JP2002516662A (ja) 2002-06-11

Similar Documents

Publication Publication Date Title
CN1191362C (zh) 新颖的链球菌抗原
CN1268745C (zh) B组链球菌抗原
CN1200731C (zh) 用作疫苗的肺炎球菌胆碱结合蛋白衍生物
CN1284965A (zh) 脑膜炎奈瑟氏球菌的新表面蛋白
CN1449446A (zh) 链球菌抗原
CN1191851C (zh) 包含胆碱结合蛋白an-末端截取物的氨基酸的多肽、由该多肽衍生的疫苗及其应用
US7479282B2 (en) Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
CN1628249A (zh) 副结核分枝杆菌感染的诊断和疫苗
CN1204253C (zh) 奈瑟氏球菌乳铁蛋白结合蛋白
CN1675241A (zh) 免疫偶联物
CN1245419C (zh) 脑膜炎奈瑟氏球菌(Neisseria meningitidis)的多核苷酸和多肽BASB033及其用途
CN1210401C (zh) 源自粘膜炎莫拉氏菌的化合物
CN1330662A (zh) 幽门螺杆菌抗原
CN1219969A (zh) 溶血巴斯德氏菌运铁蛋白结合蛋白和包含该蛋白质的疫苗
CN1220701C (zh) 重组人外周淋巴组织趋化性细胞因子及其制备方法和用途
CN1514879A (zh) 粘膜炎莫拉氏菌(布兰汉氏菌)抗原
CN1906299A (zh) 抗衣原体感染的免疫接种
CN1745096A (zh) 卡他莫拉氏菌的交叉保护表位和其使用方法
CN1549727A (zh) 粘膜炎莫拉氏(布拉汉氏)菌多肽及相应dna片段
CN1670204A (zh) 肺炎链球菌自溶酶,其编码核酸及其应用
CN1267730A (zh) 一种新的人钾离子通道调节因子蛋白及其编码序列
CN1222935A (zh) 用于前列腺癌的免疫治疗和免疫诊断的化合物及方法
CN1390852A (zh) 人类心房颤动致病基因和编码蛋白及其用途
CN1269419A (zh) 一种新的人氮代谢抑制调节因子蛋白及其编码序列
CN1402785A (zh) 新化合物

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050309

Termination date: 20170407

CF01 Termination of patent right due to non-payment of annual fee