KR100638503B1 - Ｎ-말단 콜린 결합 단백질 ａ 절두물의 아미노산을 포함하는 폴리펩티드, 이로부터 유도된 백신 및 이를 포함하는 약제학적 조성물 - Google Patents

Ｎ-말단 콜린 결합 단백질 ａ 절두물의 아미노산을 포함하는 폴리펩티드, 이로부터 유도된 백신 및 이를 포함하는 약제학적 조성물 Download PDF

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Publication number
KR100638503B1
KR100638503B1 KR1020007011206A KR20007011206A KR100638503B1 KR 100638503 B1 KR100638503 B1 KR 100638503B1 KR 1020007011206 A KR1020007011206 A KR 1020007011206A KR 20007011206 A KR20007011206 A KR 20007011206A KR 100638503 B1 KR100638503 B1 KR 100638503B1
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South Korea
Prior art keywords
amino acid
seq
position corresponding
substitution
acid residue
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Expired - Fee Related
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KR1020007011206A
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English (en)
Korean (ko)
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KR20010052244A (ko
Inventor
투오마넨엘레인아이
마수어에이치로버트
비제만테레사엠
존슨레슬릭시드너
쾨니히스콧
Original Assignee
세인트 쥬드 칠드런즈 리써치 호스피탈
메디뮨 인코포레이티드
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Priority claimed from US09/056,019 external-priority patent/US6858706B2/en
Application filed by 세인트 쥬드 칠드런즈 리써치 호스피탈, 메디뮨 인코포레이티드 filed Critical 세인트 쥬드 칠드런즈 리써치 호스피탈
Publication of KR20010052244A publication Critical patent/KR20010052244A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020007011206A 1998-04-07 1999-04-07 Ｎ-말단 콜린 결합 단백질 ａ 절두물의 아미노산을 포함하는 폴리펩티드, 이로부터 유도된 백신 및 이를 포함하는 약제학적 조성물 Expired - Fee Related KR100638503B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US60/080,878 1998-04-07
US09/056,019 1998-04-07
US09/056,019 US6858706B2 (en) 1998-04-07 1998-04-07 Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
US9/056,019 1998-04-07

Publications (2)

Publication Number Publication Date
KR20010052244A KR20010052244A (ko) 2001-06-25
KR100638503B1 true KR100638503B1 (ko) 2006-10-26

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KR1020007011206A Expired - Fee Related KR100638503B1 (ko) 1998-04-07 1999-04-07 Ｎ-말단 콜린 결합 단백질 ａ 절두물의 아미노산을 포함하는 폴리펩티드, 이로부터 유도된 백신 및 이를 포함하는 약제학적 조성물

Country Status (14)

Country Link
JP (1) JP4739521B2 (enExample)
KR (1) KR100638503B1 (enExample)
CN (1) CN1191851C (enExample)
AU (2) AU764811B2 (enExample)
BR (1) BR9909910A (enExample)
CA (1) CA2326388C (enExample)
HU (1) HUP0102306A3 (enExample)
IL (1) IL138939A0 (enExample)
MX (1) MXPA00009899A (enExample)
NO (1) NO20005081L (enExample)
NZ (1) NZ507983A (enExample)
PL (1) PL193132B1 (enExample)
TR (1) TR200003498T2 (enExample)
WO (1) WO1999051188A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
DK2384765T3 (en) 2005-12-22 2017-01-09 Glaxosmithkline Biologicals Sa Vaccine against Streptococcus pneumoniae.
EP2687228B1 (en) 2007-06-26 2017-07-19 GlaxoSmithKline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
ES2678694T3 (es) 2008-04-16 2018-08-16 Glaxosmithkline Biologicals Sa Vacuna
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
WO2012156391A1 (en) 2011-05-17 2012-11-22 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
JP2000511411A (ja) * 1996-05-01 2000-09-05 ザ ロックフェラー ユニヴァーシティ 抗―肺炎球菌ワクチン用のコリン結合タンパク質
US6420135B1 (en) * 1996-10-31 2002-07-16 Human Genome Sciences, Inc. Streptococcus pneumoniae polynucleotides and sequences
EP0942984A2 (en) * 1996-11-12 1999-09-22 Regents Of The University Of Minnesota C3 BINDING PROTEIN OF $i(STREPTOCOCCUS PNEUMONIAE)
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
CN1200731C (zh) * 1998-04-07 2005-05-11 免疫医疗公司 用作疫苗的肺炎球菌胆碱结合蛋白衍生物

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Publication number Publication date
JP4739521B2 (ja) 2011-08-03
TR200003498T2 (tr) 2001-10-22
WO1999051188A2 (en) 1999-10-14
MXPA00009899A (es) 2002-05-08
HUP0102306A1 (hu) 2001-09-28
PL347946A1 (en) 2002-04-22
AU3479799A (en) 1999-10-25
NO20005081D0 (no) 2000-10-09
CN1342088A (zh) 2002-03-27
JP2002516662A (ja) 2002-06-11
IL138939A0 (en) 2001-11-25
WO1999051188A9 (en) 2000-10-12
PL193132B1 (pl) 2007-01-31
HUP0102306A3 (en) 2008-04-28
NZ507983A (en) 2004-03-26
NO20005081L (no) 2000-12-06
BR9909910A (pt) 2002-01-15
CA2326388C (en) 2014-02-04
AU3479699A (en) 1999-10-25
CA2326388A1 (en) 1999-10-14
AU764811B2 (en) 2003-08-28
CN1191851C (zh) 2005-03-09
KR20010052244A (ko) 2001-06-25
WO1999051188A3 (en) 2001-04-19

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