CN118891273A - 膜联蛋白a1衍生的多肽类似物 - Google Patents

膜联蛋白a1衍生的多肽类似物 Download PDF

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Publication number
CN118891273A
CN118891273A CN202380023372.3A CN202380023372A CN118891273A CN 118891273 A CN118891273 A CN 118891273A CN 202380023372 A CN202380023372 A CN 202380023372A CN 118891273 A CN118891273 A CN 118891273A
Authority
CN
China
Prior art keywords
lys
polypeptide
seq
amino acid
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380023372.3A
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English (en)
Chinese (zh)
Inventor
托马斯·恩格尔布雷希特·诺克尔德·约纳森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lesoth Pharmaceutical Co ltd
Original Assignee
Lesoth Pharmaceutical Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lesoth Pharmaceutical Co ltd filed Critical Lesoth Pharmaceutical Co ltd
Publication of CN118891273A publication Critical patent/CN118891273A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721—Lipocortins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202380023372.3A 2022-02-23 2023-02-23 膜联蛋白a1衍生的多肽类似物 Pending CN118891273A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22158253.9 2022-02-23
EP22158253 2022-02-23
PCT/EP2023/054519 WO2023161323A1 (en) 2022-02-23 2023-02-23 Annexin a1-derived polypeptide analogues

Publications (1)

Publication Number Publication Date
CN118891273A true CN118891273A (zh) 2024-11-01

Family

ID=80461005

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380023372.3A Pending CN118891273A (zh) 2022-02-23 2023-02-23 膜联蛋白a1衍生的多肽类似物

Country Status (7)

Country Link
US (1) US20250388632A1 (enExample)
EP (1) EP4482853A1 (enExample)
JP (1) JP2025506775A (enExample)
CN (1) CN118891273A (enExample)
AU (1) AU2023226134A1 (enExample)
CA (1) CA3249181A1 (enExample)
WO (1) WO2023161323A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025083393A1 (en) * 2023-10-16 2025-04-24 Therakind Limited Antimicrobial use of peptides derived from annexin a1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050118688A1 (en) * 2001-12-28 2005-06-02 Hudson Freeze Novel ligand involved in the transmigration of leukocytes across the endothelium and uses therefor
FR2856069A1 (fr) * 2003-06-10 2004-12-17 Bionexis Molecules de ciblage et de liberation de composes therapeutiques et leur utilisation
BR112013032088B1 (pt) 2011-06-15 2020-11-24 Resother Pharma Aps produtos farmacêuticos anti-inflamatórios
KR20150029457A (ko) * 2013-09-10 2015-03-18 삼성전자주식회사 아넥신 a1에 결합하는 폴리펩타이드 및 그의 용도
HUE052977T2 (hu) 2014-04-22 2021-06-28 Txp Pharma Gmbh Elágazó szénláncú aminosav-próbával rendelkezõ peptid analóg(ok)

Also Published As

Publication number Publication date
EP4482853A1 (en) 2025-01-01
US20250388632A1 (en) 2025-12-25
WO2023161323A1 (en) 2023-08-31
AU2023226134A1 (en) 2024-08-01
JP2025506775A (ja) 2025-03-13
CA3249181A1 (en) 2023-08-31

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