CN117683886A - 一种检测胃癌的miRNA标志物组合及试剂盒 - Google Patents

一种检测胃癌的miRNA标志物组合及试剂盒 Download PDF

Info

Publication number
CN117683886A
CN117683886A CN202311539926.3A CN202311539926A CN117683886A CN 117683886 A CN117683886 A CN 117683886A CN 202311539926 A CN202311539926 A CN 202311539926A CN 117683886 A CN117683886 A CN 117683886A
Authority
CN
China
Prior art keywords
hsa
mir
mirna
marker combination
mirna marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202311539926.3A
Other languages
English (en)
Chinese (zh)
Inventor
邹瑞阳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Miyin Biotechnology Co ltd
Mirxes Lab Pte Ltd
Original Assignee
Hangzhou Miyin Biotechnology Co ltd
Mirxes Lab Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hangzhou Miyin Biotechnology Co ltd, Mirxes Lab Pte Ltd filed Critical Hangzhou Miyin Biotechnology Co ltd
Priority to CN202311539926.3A priority Critical patent/CN117683886A/zh
Publication of CN117683886A publication Critical patent/CN117683886A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202311539926.3A 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒 Pending CN117683886A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311539926.3A CN117683886A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910392316.2A CN110029169A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN202311539926.3A CN117683886A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201910392316.2A Division CN110029169A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒

Publications (1)

Publication Number Publication Date
CN117683886A true CN117683886A (zh) 2024-03-12

Family

ID=67241908

Family Applications (4)

Application Number Title Priority Date Filing Date
CN202311539926.3A Pending CN117683886A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN202211194423.2A Pending CN115537466A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN201910392316.2A Pending CN110029169A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN202311539925.9A Pending CN117683885A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN202211194423.2A Pending CN115537466A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN201910392316.2A Pending CN110029169A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN202311539925.9A Pending CN117683885A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒

Country Status (13)

Country Link
US (1) US20220186320A1 (https=)
EP (1) EP3967767A4 (https=)
JP (2) JP7676321B2 (https=)
KR (1) KR20220009970A (https=)
CN (4) CN117683886A (https=)
AU (1) AU2020265027A1 (https=)
BR (1) BR112021021856A2 (https=)
CL (1) CL2021002852A1 (https=)
CO (1) CO2021015520A2 (https=)
MX (1) MX2021013424A (https=)
PH (1) PH12021552764A1 (https=)
SG (1) SG11202112095VA (https=)
WO (1) WO2020220994A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117683886A (zh) * 2019-04-30 2024-03-12 觅瑞实验室私人有限公司 一种检测胃癌的miRNA标志物组合及试剂盒
CN111321224B (zh) * 2019-12-27 2023-09-15 陈锦飞 一种用于诊断或辅助诊断胃癌的miRNA生物标志物组合及其试剂盒
CN111471764B (zh) * 2019-12-27 2023-09-15 陈锦飞 一种用于筛查或辅助诊断胃癌的生物标志物组合及其试剂盒和应用
CN111312405A (zh) * 2020-02-12 2020-06-19 宁德市闽东医院 一种健康体检胃癌筛查评估及管理系统
CN111471683B (zh) * 2020-04-15 2021-09-07 湖南省科域生物医药科技有限公司 miR-93-5p作为诊断和治疗胃癌标志物的应用
CN112226514B (zh) * 2020-11-23 2021-08-03 苏州京脉生物科技有限公司 用于早期胃癌检测的标志物组合、试剂盒及其应用
CN113151413A (zh) * 2021-04-28 2021-07-23 杭州觅因生物科技有限公司 一种具有校准功能的microRNA检测试剂盒
CN113186285B (zh) * 2021-05-10 2022-05-24 深圳市展行生物有限公司 一种辅助诊断胃癌的方法及其使用的miRNA组合
CN114875151B (zh) * 2022-06-15 2023-05-16 北京肿瘤医院(北京大学肿瘤医院) 血浆外泌体生物标志物在胃癌新辅助化疗敏感人群筛查或疗效预测中的应用
CN116179691A (zh) * 2022-09-07 2023-05-30 苏州大学附属第一医院 一种胃癌组合标志物及标志物模型的建立方法
CN116926192B (zh) * 2023-05-17 2025-01-24 山东大学 一种基于链置换反应的肿瘤标志物miRNA与mRNA荧光共检测方法及其在胃癌诊断中的应用
CN119351558A (zh) * 2024-12-10 2025-01-24 西藏自治区人民政府驻成都办事处医院 一种检测胃癌的标志物、检测试剂盒及药物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2716906A1 (en) * 2008-02-28 2009-09-03 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis, prognosis and treatment of gastric cancer
CN102892897B (zh) * 2009-12-24 2016-08-03 复旦大学 用于肺癌的微rna表达谱分析的组合物和方法
US9850527B2 (en) 2010-06-14 2017-12-26 National University Of Singapore Modified stem-loop oligonucleotide mediated reverse transcription and base-spacing constrained quantitative PCR
KR101381894B1 (ko) * 2012-02-28 2014-04-14 부산대학교 산학협력단 위암의 림프절 전이 진단 마커로서의 혈청 ｍｉＲＮＡ
CN103937888B (zh) * 2014-04-14 2016-08-17 上海交通大学 鉴别胃癌的血浆microRNA标志物的筛选与应用
EP4718079A2 (en) * 2014-06-16 2026-04-01 Toray Industries, Inc. Stomach cancer biomarker and detection method
EP3177739B1 (en) * 2014-08-07 2019-10-23 Agency For Science, Technology And Research Microrna biomarker for the diagnosis of gastric cancer
WO2016034715A2 (fr) * 2014-09-05 2016-03-10 Prestizia Methode de prediction de l'evolution clinique du cancer colorectal
WO2016144265A1 (en) * 2015-03-09 2016-09-15 Agency For Science, Technology And Research Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas)
CN105219867B (zh) * 2015-11-02 2016-08-17 北京博奥医学检验所有限公司 用于胃癌诊断的miRNA生物标志物及检测试剂盒
CN106086178B (zh) * 2016-06-16 2020-03-31 朱伟 一种与胃癌辅助诊断相关的血清miRNA标志物及其应用
CN106755377B (zh) * 2016-12-12 2021-05-25 浙江省中医院 一种胃癌血清学检测鉴定试剂盒及方法
CN107746880B (zh) * 2017-11-01 2018-12-14 健生生物技术有限公司 一种基于RT-qPCR法检测胃癌的试剂盒及其制备方法和应用
CN109609630B (zh) * 2018-12-03 2023-01-13 哈尔滨医科大学 用于早期胃癌诊断的分子标志物及其应用
CN117683886A (zh) * 2019-04-30 2024-03-12 觅瑞实验室私人有限公司 一种检测胃癌的miRNA标志物组合及试剂盒

Also Published As

Publication number Publication date
JP2025114665A (ja) 2025-08-05
WO2020220994A1 (zh) 2020-11-05
CL2021002852A1 (es) 2022-06-10
EP3967767A4 (en) 2023-06-14
JP7676321B2 (ja) 2025-05-14
MX2021013424A (es) 2022-02-11
CN117683885A (zh) 2024-03-12
EP3967767A1 (en) 2022-03-16
AU2020265027A1 (en) 2021-12-09
CN115537466A (zh) 2022-12-30
CN110029169A (zh) 2019-07-19
KR20220009970A (ko) 2022-01-25
PH12021552764A1 (en) 2022-07-11
US20220186320A1 (en) 2022-06-16
CO2021015520A2 (es) 2022-01-17
BR112021021856A2 (pt) 2022-01-18
JP2022533033A (ja) 2022-07-21
SG11202112095VA (en) 2021-12-30

Similar Documents

Publication Publication Date Title
CN117683886A (zh) 一种检测胃癌的miRNA标志物组合及试剂盒
CN103667516B (zh) 早期结直肠腺癌miRNAs检测试剂盒或生物芯片
JP2012521772A (ja) 癌の診断及び癌処置のモニタリングのための方法
CN110484624B (zh) 一种基于外周血的胃癌生物标志物及其检测方法和应用
CN107435062B (zh) 甄别肺部微小结节良恶性的外周血基因标志物及其用途
CN110229899B (zh) 用于结直肠癌早期诊断或预后预测的血浆标记物组合
CN113584169A (zh) 一种与肝癌相关的血清tsRNA标志物、探针及其应用
JP7345860B2 (ja) 胃癌バイオマーカー及びその用途
CN114107498A (zh) 结直肠癌血液检测标记物及其应用
CN108796082B (zh) 长链非编码RNAs的应用
US20220025467A1 (en) Kcnq1ot1, a new biomarker in peripheral blood for non-invasive detection of gastric cancer (gc)
CN117106918A (zh) 基因甲基化鉴别诊断肺良性结节和恶性肿瘤方法及其试剂盒
CN108998530A (zh) 肺癌上调长链非编码rna标志物及其应用
JP7299765B2 (ja) マイクロｒｎａ測定方法およびキット
JP6103866B2 (ja) 大腸ガン検出方法、診断用キット及びｄｎａチップ
CN114292920A (zh) 一组胃癌前病变及胃癌早期诊断血浆rna标志物组合及应用
CN109182520B (zh) 一种宫颈癌及其癌前病变检测试剂盒及其应用
CN108424960B (zh) 一种LncRNA作为深静脉血栓形成诊断标志物的应用
CN115961048B (zh) 一种基因甲基化检测引物组合、试剂及其应用
TWI626314B (zh) 評估罹患大腸直腸癌風險的方法
HK40068245A (en) Microrna marker combination for diagnosing gastric cancer and diagnostic kit
CN116004821A (zh) 用于检测肠癌的标记物及其应用
CN111187836B (zh) 泌尿上皮癌的检测套组及微型核糖核酸组合物在制备用于预测泌尿上皮癌检测套组中的应用
CN108588217B (zh) 一种LncRNA作为深静脉血栓形成诊断标志物的应用
CN114790482A (zh) 一种筛查或辅助筛查结直肠癌的方法及其使用的miRNA组合

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination