KR20220009970A - 위암 진단용 마이크로rna 마커 조합 및 진단 키트 - Google Patents

위암 진단용 마이크로rna 마커 조합 및 진단 키트 Download PDF

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KR20220009970A
KR20220009970A KR1020217039294A KR20217039294A KR20220009970A KR 20220009970 A KR20220009970 A KR 20220009970A KR 1020217039294 A KR1020217039294 A KR 1020217039294A KR 20217039294 A KR20217039294 A KR 20217039294A KR 20220009970 A KR20220009970 A KR 20220009970A
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mir
hsa
mirna
gastric cancer
mirna marker
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KR1020217039294A
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Korean (ko)
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루이양 쩌우
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머크시즈 랩 피티이.엘티디.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020217039294A 2019-04-30 2020-04-14 위암 진단용 마이크로rna 마커 조합 및 진단 키트 Ceased KR20220009970A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201910392316.2A CN110029169A (zh) 2019-04-30 2019-04-30 一种检测胃癌的miRNA标志物组合及试剂盒
CN201910392316.2 2019-04-30
PCT/CN2020/084687 WO2020220994A1 (zh) 2019-04-30 2020-04-14 一种检测胃癌的miRNA标志物组合及试剂盒

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KR20220009970A true KR20220009970A (ko) 2022-01-25

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KR1020217039294A Ceased KR20220009970A (ko) 2019-04-30 2020-04-14 위암 진단용 마이크로rna 마커 조합 및 진단 키트

Country Status (13)

Country Link
US (1) US20220186320A1 (https=)
EP (1) EP3967767A4 (https=)
JP (2) JP7676321B2 (https=)
KR (1) KR20220009970A (https=)
CN (4) CN117683886A (https=)
AU (1) AU2020265027A1 (https=)
BR (1) BR112021021856A2 (https=)
CL (1) CL2021002852A1 (https=)
CO (1) CO2021015520A2 (https=)
MX (1) MX2021013424A (https=)
PH (1) PH12021552764A1 (https=)
SG (1) SG11202112095VA (https=)
WO (1) WO2020220994A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117683886A (zh) * 2019-04-30 2024-03-12 觅瑞实验室私人有限公司 一种检测胃癌的miRNA标志物组合及试剂盒
CN111321224B (zh) * 2019-12-27 2023-09-15 陈锦飞 一种用于诊断或辅助诊断胃癌的miRNA生物标志物组合及其试剂盒
CN111471764B (zh) * 2019-12-27 2023-09-15 陈锦飞 一种用于筛查或辅助诊断胃癌的生物标志物组合及其试剂盒和应用
CN111312405A (zh) * 2020-02-12 2020-06-19 宁德市闽东医院 一种健康体检胃癌筛查评估及管理系统
CN111471683B (zh) * 2020-04-15 2021-09-07 湖南省科域生物医药科技有限公司 miR-93-5p作为诊断和治疗胃癌标志物的应用
CN112226514B (zh) * 2020-11-23 2021-08-03 苏州京脉生物科技有限公司 用于早期胃癌检测的标志物组合、试剂盒及其应用
CN113151413A (zh) * 2021-04-28 2021-07-23 杭州觅因生物科技有限公司 一种具有校准功能的microRNA检测试剂盒
CN113186285B (zh) * 2021-05-10 2022-05-24 深圳市展行生物有限公司 一种辅助诊断胃癌的方法及其使用的miRNA组合
CN114875151B (zh) * 2022-06-15 2023-05-16 北京肿瘤医院(北京大学肿瘤医院) 血浆外泌体生物标志物在胃癌新辅助化疗敏感人群筛查或疗效预测中的应用
CN116179691A (zh) * 2022-09-07 2023-05-30 苏州大学附属第一医院 一种胃癌组合标志物及标志物模型的建立方法
CN116926192B (zh) * 2023-05-17 2025-01-24 山东大学 一种基于链置换反应的肿瘤标志物miRNA与mRNA荧光共检测方法及其在胃癌诊断中的应用
CN119351558A (zh) * 2024-12-10 2025-01-24 西藏自治区人民政府驻成都办事处医院 一种检测胃癌的标志物、检测试剂盒及药物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2716906A1 (en) * 2008-02-28 2009-09-03 The Ohio State University Research Foundation Microrna-based methods and compositions for the diagnosis, prognosis and treatment of gastric cancer
CN102892897B (zh) * 2009-12-24 2016-08-03 复旦大学 用于肺癌的微rna表达谱分析的组合物和方法
US9850527B2 (en) 2010-06-14 2017-12-26 National University Of Singapore Modified stem-loop oligonucleotide mediated reverse transcription and base-spacing constrained quantitative PCR
KR101381894B1 (ko) * 2012-02-28 2014-04-14 부산대학교 산학협력단 위암의 림프절 전이 진단 마커로서의 혈청 ｍｉＲＮＡ
CN103937888B (zh) * 2014-04-14 2016-08-17 上海交通大学 鉴别胃癌的血浆microRNA标志物的筛选与应用
EP4718079A2 (en) * 2014-06-16 2026-04-01 Toray Industries, Inc. Stomach cancer biomarker and detection method
EP3177739B1 (en) * 2014-08-07 2019-10-23 Agency For Science, Technology And Research Microrna biomarker for the diagnosis of gastric cancer
WO2016034715A2 (fr) * 2014-09-05 2016-03-10 Prestizia Methode de prediction de l'evolution clinique du cancer colorectal
WO2016144265A1 (en) * 2015-03-09 2016-09-15 Agency For Science, Technology And Research Method of determining the risk of developing breast cancer by detecting the expression levels of micrornas (mirnas)
CN105219867B (zh) * 2015-11-02 2016-08-17 北京博奥医学检验所有限公司 用于胃癌诊断的miRNA生物标志物及检测试剂盒
CN106086178B (zh) * 2016-06-16 2020-03-31 朱伟 一种与胃癌辅助诊断相关的血清miRNA标志物及其应用
CN106755377B (zh) * 2016-12-12 2021-05-25 浙江省中医院 一种胃癌血清学检测鉴定试剂盒及方法
CN107746880B (zh) * 2017-11-01 2018-12-14 健生生物技术有限公司 一种基于RT-qPCR法检测胃癌的试剂盒及其制备方法和应用
CN109609630B (zh) * 2018-12-03 2023-01-13 哈尔滨医科大学 用于早期胃癌诊断的分子标志物及其应用
CN117683886A (zh) * 2019-04-30 2024-03-12 觅瑞实验室私人有限公司 一种检测胃癌的miRNA标志物组合及试剂盒

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JP2025114665A (ja) 2025-08-05
WO2020220994A1 (zh) 2020-11-05
CL2021002852A1 (es) 2022-06-10
CN117683886A (zh) 2024-03-12
EP3967767A4 (en) 2023-06-14
JP7676321B2 (ja) 2025-05-14
MX2021013424A (es) 2022-02-11
CN117683885A (zh) 2024-03-12
EP3967767A1 (en) 2022-03-16
AU2020265027A1 (en) 2021-12-09
CN115537466A (zh) 2022-12-30
CN110029169A (zh) 2019-07-19
PH12021552764A1 (en) 2022-07-11
US20220186320A1 (en) 2022-06-16
CO2021015520A2 (es) 2022-01-17
BR112021021856A2 (pt) 2022-01-18
JP2022533033A (ja) 2022-07-21
SG11202112095VA (en) 2021-12-30

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