CN1165312C - 加氢甾醇组合物及其应用 - Google Patents

加氢甾醇组合物及其应用 Download PDF

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Publication number
CN1165312C
CN1165312C CNB961804068A CN96180406A CN1165312C CN 1165312 C CN1165312 C CN 1165312C CN B961804068 A CNB961804068 A CN B961804068A CN 96180406 A CN96180406 A CN 96180406A CN 1165312 C CN1165312 C CN 1165312C
Authority
CN
China
Prior art keywords
cholesterol
campesterol
fatty acid
hydrosterol
sitosterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB961804068A
Other languages
English (en)
Chinese (zh)
Other versions
CN1228025A (zh
Inventor
��ɪά��
I·维斯特
��Ī������
T·帕尔莫
T·迈特提恩
H·盖勒林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RAISION BINIKAU Oy AB
Original Assignee
RAISION BINIKAU Oy AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8546469&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1165312(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by RAISION BINIKAU Oy AB filed Critical RAISION BINIKAU Oy AB
Publication of CN1228025A publication Critical patent/CN1228025A/zh
Application granted granted Critical
Publication of CN1165312C publication Critical patent/CN1165312C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Edible Oils And Fats (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB961804068A 1996-08-09 1996-09-02 加氢甾醇组合物及其应用 Expired - Lifetime CN1165312C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI963126A FI107015B (fi) 1996-08-09 1996-08-09 Kasvistanolirasvahappoestereiden seos ja sen käyttö sekä elintarvike
FI963126 1996-08-09

Publications (2)

Publication Number Publication Date
CN1228025A CN1228025A (zh) 1999-09-08
CN1165312C true CN1165312C (zh) 2004-09-08

Family

ID=8546469

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB961804068A Expired - Lifetime CN1165312C (zh) 1996-08-09 1996-09-02 加氢甾醇组合物及其应用

Country Status (27)

Country Link
EP (2) EP1452180A1 (enExample)
JP (3) JP2000513730A (enExample)
KR (1) KR100440640B1 (enExample)
CN (1) CN1165312C (enExample)
AT (1) ATE266408T1 (enExample)
AU (1) AU734418B2 (enExample)
BR (1) BRPI9612693B8 (enExample)
CA (1) CA2262600C (enExample)
CZ (1) CZ290903B6 (enExample)
DE (1) DE69632481T3 (enExample)
DK (1) DK0871451T4 (enExample)
EE (1) EE03747B1 (enExample)
ES (1) ES2220986T5 (enExample)
FI (1) FI107015B (enExample)
HU (1) HU228301B1 (enExample)
IL (1) IL128458A (enExample)
LT (1) LT4649B (enExample)
LV (1) LV12307B (enExample)
NO (1) NO326262B1 (enExample)
NZ (1) NZ334496A (enExample)
PL (1) PL331515A1 (enExample)
PT (1) PT871451E (enExample)
SI (1) SI9620141B (enExample)
SK (1) SK285849B6 (enExample)
UA (1) UA66763C2 (enExample)
WO (1) WO1998006405A1 (enExample)
ZA (1) ZA967616B (enExample)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664827B2 (en) 1991-05-03 1995-12-07 Raisio Benecol Ltd. A substance for lowering high cholesterol level in serum and a method for preparing the same
US6544973B1 (en) 1995-07-28 2003-04-08 Raisio Benecol Ltd. Substance for lowering high cholesterol level in serum and methods for preparing and using the same
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US20030104035A1 (en) 1996-08-09 2003-06-05 Raisio Benecol Ltd. Stanol composition and the use thereof
US6929816B2 (en) 1998-01-21 2005-08-16 Raisio Benecol Ltd. Fat compositions for use in food
UA69378C2 (uk) * 1996-11-04 2004-09-15 Райзіо Бенекол Лтд. Текстуруюча композиція, текстуруючий агент, харчовий продукт, жирові суміші та способи їх одержання
FI107538B (fi) * 1997-02-26 2001-08-31 Raisio Benecol Oy Menetelmä stanoliesterien valmistamiseksi
ES2222553T3 (es) * 1997-08-22 2005-02-01 Unilever N.V. Producto alimenticio a base de grasa que comprende esteroles.
DE69826592T2 (de) * 1997-08-22 2006-02-23 Unilever N.V. Verfahren zur Herstellung von Stanolestern
ES2272882T3 (es) 1997-08-22 2007-05-01 Unilever N.V. Composciones que comprenden estanol.
EP0897971B1 (en) * 1997-08-22 2004-11-03 Unilever N.V. Stanol ester composition
EP1440619B1 (en) * 1997-08-22 2006-11-02 Unilever N.V. Fat based food products comprising sterols
ES2231940T3 (es) * 1997-08-22 2005-05-16 Unilever N.V. Composicion de esteres de estanol.
FI974648A7 (fi) 1997-09-09 1999-05-06 Raisio Benecol Oy Hydroksihappo-, maitohappo- ja hydroksialkanoaattiesterit ja niiden käyttö
EP1066313A1 (de) * 1998-03-23 2001-01-10 Cognis Deutschland GmbH Verfahren zur herstellung von stanolen
US6025348A (en) * 1998-04-30 2000-02-15 Kao Corporation Oil and fat composition containing phytosterol
US6123978A (en) 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6277431B1 (en) * 1998-10-14 2001-08-21 Redeem, Inc. Anticholesterolemic edible oil
FI115527B (fi) * 1998-10-16 2005-05-31 Upm Kymmene Oyj Kasvisterolijohdannaisten käyttö ja niitä sisältäviä tuotteita
ID24148A (id) * 1998-11-26 2000-07-13 Hoffmann La Roche Turunan-turunan fitostfrol dan/atau fitostanol
US6113972A (en) * 1998-12-03 2000-09-05 Monsanto Co. Phytosterol protein complex
EP1340508A1 (en) 1998-12-23 2003-09-03 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
AU3228100A (en) 1999-02-10 2000-08-29 Eastman Chemical Company Corn fiber for the production of advanced chemicals and materials
BR0010597A (pt) 1999-04-12 2002-02-13 Monsanto Technology Llc Plantas transgênicas contendo nìveis alterados de compostos esterol e tocoferóis
FI991533L (fi) * 1999-07-05 2001-01-06 Sohkar Oy Menetelmä orgaanisten aineiden käsittelemiseksi
US6998501B1 (en) 1999-08-30 2006-02-14 Ocean Nutrition Canada Limited Nutritional supplement for lowering serum triglyceride and cholesterol levels
US7157619B1 (en) 1999-08-30 2007-01-02 Monsanto Technology, L.L.C. Plant sterol acyltransferases
AU6813700A (en) * 1999-08-30 2001-03-26 Ocean Nutrition Canada Ltd. A nutritional supplement for lowering serum triglyceride and cholesterol levels
US6677327B1 (en) 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
ATE323714T1 (de) * 2000-01-21 2006-05-15 Forbes Medi Tech Inc Krystalline zusammensetzungen enthaltend phytosterole und phytostanole oder derivate davon
EP1252137A1 (en) 2000-01-28 2002-10-30 The Procter & Gamble Company Palatable arginine compounds and uses thereof for cardiovascular health
DK1121928T3 (da) * 2000-01-31 2008-03-17 Haerting S A Sammensætninger indeholdende phytosterol- og policosanolestere af fedtsyrer til reduktion af niveauet af blodcholesterol og -triglycerider
JP4970690B2 (ja) 2000-04-14 2012-07-11 マース インコーポレーテッド 血管の健康状態を改善するための組成物および方法
FI20010780A0 (fi) * 2001-04-12 2001-04-12 Raisio Benecol Oy Parannetut koostumukset
CA2471639A1 (en) 2002-01-17 2003-07-31 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
US20080182801A1 (en) 2003-12-22 2008-07-31 Btg International Limited Core 2 glcnac-t inhibitors
GB0513881D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors III
GB0329667D0 (en) 2003-12-22 2004-01-28 King S College London Core 2 GlcNAc-T inhibitor
US8158184B2 (en) 2004-03-08 2012-04-17 Bunge Oils, Inc. Structured lipid containing compositions and methods with health and nutrition promoting characteristics
GB0513888D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
GB0513883D0 (en) 2005-07-06 2005-08-10 Btg Int Ltd Diagnosis of Atherosclerosis
IE20060710A1 (en) * 2005-09-28 2007-07-25 Alltracel Dev Services Ltd Use of polyanhydroglucronic acid
JP2009521416A (ja) * 2005-12-20 2009-06-04 フォーブス メディ−テック インコーポレーテッド 水相中にエステル化されていないフィトステロールを含むエマルジョン
US20070148311A1 (en) 2005-12-22 2007-06-28 Bunge Oils, Inc. Phytosterol esterification product and method of make same
AU2007222697B2 (en) * 2006-03-08 2012-07-05 Cognis Ip Management Gmbh Powder containing sterol
DE102006041302A1 (de) * 2006-03-08 2007-09-13 Cognis Ip Management Gmbh Sterolester mit kurzkettigen Fettsäuren
US20080124387A1 (en) 2006-11-27 2008-05-29 Kapac, Llc Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients
FI123374B (fi) 2011-03-25 2013-03-15 Ravintoraisio Oy Uusi syötävä koostumus
PL3287014T3 (pl) * 2016-08-22 2020-08-24 Verbio Vereinigte Bioenergie Ag Sposób wytwarzania kompozycji fitosteroli-fitostanoli
WO2021170873A1 (en) * 2020-02-27 2021-09-02 Basf Se Composition for the treatment of (pre)hypercholesterolemia and/or associated morbidities thereto
GB202110358D0 (en) * 2021-07-19 2021-09-01 Meda Pharma S P A Composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664827B2 (en) * 1991-05-03 1995-12-07 Raisio Benecol Ltd. A substance for lowering high cholesterol level in serum and a method for preparing the same
US5244887A (en) * 1992-02-14 1993-09-14 Straub Carl D Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof

Also Published As

Publication number Publication date
ATE266408T1 (de) 2004-05-15
CZ290903B6 (cs) 2002-11-13
LT4649B (lt) 2000-04-25
LT99018A (lt) 1999-12-27
HUP0001020A2 (hu) 2000-08-28
ES2220986T5 (es) 2008-11-01
AU734418B2 (en) 2001-06-14
HU228301B1 (en) 2013-03-28
HUP0001020A3 (en) 2001-10-29
EP0871451A1 (en) 1998-10-21
NO990559L (no) 1999-02-05
IL128458A (en) 2004-07-25
JP4554915B2 (ja) 2010-09-29
LV12307A (lv) 1999-07-20
JP2000513730A (ja) 2000-10-17
PL331515A1 (en) 1999-07-19
JP2009102421A (ja) 2009-05-14
SI9620141A (sl) 1999-10-31
CA2262600A1 (en) 1998-02-19
DK0871451T3 (da) 2004-09-20
BRPI9612693B8 (pt) 2016-04-26
EE03747B1 (et) 2002-06-17
JP2004143181A (ja) 2004-05-20
EP0871451B1 (en) 2004-05-12
BRPI9612693B1 (pt) 2016-04-12
FI107015B (fi) 2001-05-31
DE69632481D1 (de) 2004-06-17
EE9900040A (et) 1999-08-16
NO326262B1 (no) 2008-10-27
SK285849B6 (sk) 2007-09-06
AU6823096A (en) 1998-03-06
ZA967616B (en) 1997-04-16
NO990559D0 (no) 1999-02-05
EP0871451B2 (en) 2008-07-09
IL128458A0 (en) 2000-01-31
BR9612693A (pt) 1999-12-28
LV12307B (en) 1999-10-20
CA2262600C (en) 2009-11-17
NZ334496A (en) 2000-07-28
DE69632481T3 (de) 2008-11-27
EP1452180A1 (en) 2004-09-01
FI963126L (fi) 1998-02-10
DE69632481T2 (de) 2005-05-12
UA66763C2 (en) 2004-06-15
PT871451E (pt) 2004-09-30
SI9620141B (sl) 2008-10-31
DK0871451T4 (da) 2008-11-10
WO1998006405A1 (en) 1998-02-19
KR20000029884A (ko) 2000-05-25
KR100440640B1 (ko) 2004-07-19
SK11299A3 (en) 1999-09-10
FI963126A0 (fi) 1996-08-09
CN1228025A (zh) 1999-09-08
CZ34699A3 (cs) 1999-07-14
ES2220986T3 (es) 2004-12-16

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PB01 Publication
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SE01 Entry into force of request for substantive examination
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GR01 Patent grant
CX01 Expiry of patent term

Granted publication date: 20040908

EXPY Termination of patent right or utility model