CN1165301C - 组合物在制备治疗癌症的药物中的用途 - Google Patents
组合物在制备治疗癌症的药物中的用途 Download PDFInfo
- Publication number
- CN1165301C CN1165301C CNB998139181A CN99813918A CN1165301C CN 1165301 C CN1165301 C CN 1165301C CN B998139181 A CNB998139181 A CN B998139181A CN 99813918 A CN99813918 A CN 99813918A CN 1165301 C CN1165301 C CN 1165301C
- Authority
- CN
- China
- Prior art keywords
- cell
- compositions
- acid
- ascorbate
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (2)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1999/019449 WO2001015692A1 (en) | 1999-08-30 | 1999-08-30 | Methods and compositions for selective cancer chemotherapy |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1329489A CN1329489A (zh) | 2002-01-02 |
CN1165301C true CN1165301C (zh) | 2004-09-08 |
Family
ID=22273462
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB998139181A Expired - Fee Related CN1165301C (zh) | 1999-08-30 | 1999-08-30 | 组合物在制备治疗癌症的药物中的用途 |
Country Status (16)
Country | Link |
---|---|
US (1) | US20040092549A1 (zh) |
EP (1) | EP1124550B9 (zh) |
JP (1) | JP2003508437A (zh) |
CN (1) | CN1165301C (zh) |
AT (1) | ATE401071T1 (zh) |
AU (1) | AU783283B2 (zh) |
CA (1) | CA2348565A1 (zh) |
CY (1) | CY1108293T1 (zh) |
DE (1) | DE69939123D1 (zh) |
DK (1) | DK1124550T3 (zh) |
ES (1) | ES2310941T3 (zh) |
NO (1) | NO326995B1 (zh) |
NZ (1) | NZ511396A (zh) |
PT (1) | PT1124550E (zh) |
TW (1) | TWI245643B (zh) |
WO (1) | WO2001015692A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001280448B8 (en) * | 1998-01-05 | 2008-05-29 | The Ester C Company | Vitamin C Compositions |
US6878744B2 (en) * | 1999-02-05 | 2005-04-12 | Oxycal Laboratories, Inc. | Vitamin C compositions |
EP1282416A2 (en) * | 2000-05-19 | 2003-02-12 | Progenics Pharmaceuticals, Inc. | Dehydroascorbic acid formulations and uses thereof |
US6468980B1 (en) * | 2000-09-01 | 2002-10-22 | Oxycal Laboratories, Inc. | Methods and compositions for potentiating cancer chemotherapeutic agents |
EP2859894A1 (en) * | 2001-06-26 | 2015-04-15 | The Ester C Company | Vitamin C compositions |
GB0212405D0 (en) * | 2002-05-29 | 2002-07-10 | Insignion Holdings Ltd | Composition and its therapeutic use |
CN101506679B (zh) * | 2006-08-18 | 2013-03-06 | 通用电气医疗集团股份有限公司 | 细胞死亡的13c-mr成像或波谱分析 |
WO2010043029A1 (en) * | 2008-10-15 | 2010-04-22 | Xingnong Wang | Use of tetrose to inhibit cancer and to increase cell viability |
WO2014070769A1 (en) | 2012-10-29 | 2014-05-08 | The University Of North Carolina At Chapel Hill | Methods and compositions for treating mucosal tissue disorders |
US20210283095A1 (en) * | 2020-03-11 | 2021-09-16 | Harold E. Siess | Detection and Treatment of Viral Diseases and Cancer |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4822816A (en) * | 1987-04-10 | 1989-04-18 | Oxycal Laboratories, Inc. | Compositions and methods for administering vitamin C |
GB2208798B (en) * | 1987-07-20 | 1991-06-05 | Norsk Hydro As | Anti-cancer agent comprising l-ascorbic acid and o-benzylidene-l-ascorbic acid or deuterated derivative |
WO1990012571A1 (en) * | 1989-04-07 | 1990-11-01 | Oxycal Laboratories, Inc. | Compositions and methods for administering vitamin c |
WO1990003167A1 (en) * | 1988-09-19 | 1990-04-05 | Oxycal Laboratories, Inc. | Compositions and methods for administering therapeutically active compounds |
US5626883A (en) * | 1994-04-15 | 1997-05-06 | Metagenics, Inc. | Ascorbic acid compositions providing enhanced human immune system activity |
KR100266373B1 (ko) * | 1997-01-06 | 2000-09-15 | 더블유. 유 병 | 김치의 제조방법 |
PT982990E (pt) * | 1998-02-06 | 2007-01-31 | Ester C Company | Composições líquidas estáveis de ascorbato de cálcio e métodos de preparação e utilização |
-
1999
- 1999-08-30 WO PCT/US1999/019449 patent/WO2001015692A1/en active IP Right Grant
- 1999-08-30 DE DE69939123T patent/DE69939123D1/de not_active Expired - Lifetime
- 1999-08-30 EP EP99945197A patent/EP1124550B9/en not_active Expired - Lifetime
- 1999-08-30 NZ NZ511396A patent/NZ511396A/en not_active IP Right Cessation
- 1999-08-30 AU AU57853/99A patent/AU783283B2/en not_active Ceased
- 1999-08-30 PT PT99945197T patent/PT1124550E/pt unknown
- 1999-08-30 CA CA002348565A patent/CA2348565A1/en not_active Abandoned
- 1999-08-30 AT AT99945197T patent/ATE401071T1/de not_active IP Right Cessation
- 1999-08-30 ES ES99945197T patent/ES2310941T3/es not_active Expired - Lifetime
- 1999-08-30 JP JP2001519906A patent/JP2003508437A/ja not_active Ceased
- 1999-08-30 DK DK99945197T patent/DK1124550T3/da active
- 1999-08-30 US US09/830,912 patent/US20040092549A1/en not_active Abandoned
- 1999-08-30 CN CNB998139181A patent/CN1165301C/zh not_active Expired - Fee Related
- 1999-09-23 TW TW088116389A patent/TWI245643B/zh not_active IP Right Cessation
-
2001
- 2001-04-25 NO NO20012027A patent/NO326995B1/no not_active IP Right Cessation
-
2008
- 2008-08-25 CY CY20081100910T patent/CY1108293T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ511396A (en) | 2003-08-29 |
CN1329489A (zh) | 2002-01-02 |
NO20012027L (no) | 2001-06-20 |
AU783283B2 (en) | 2005-10-13 |
TWI245643B (en) | 2005-12-21 |
AU5785399A (en) | 2001-03-26 |
DE69939123D1 (de) | 2008-08-28 |
NO326995B1 (no) | 2009-03-30 |
EP1124550A1 (en) | 2001-08-22 |
ATE401071T1 (de) | 2008-08-15 |
JP2003508437A (ja) | 2003-03-04 |
WO2001015692A1 (en) | 2001-03-08 |
EP1124550B1 (en) | 2008-07-16 |
CA2348565A1 (en) | 2001-03-08 |
EP1124550A4 (en) | 2002-08-21 |
DK1124550T3 (da) | 2008-11-17 |
EP1124550B9 (en) | 2008-11-05 |
NO20012027D0 (no) | 2001-04-25 |
PT1124550E (pt) | 2008-08-29 |
CY1108293T1 (el) | 2014-02-12 |
US20040092549A1 (en) | 2004-05-13 |
WO2001015692A8 (en) | 2001-10-11 |
ES2310941T3 (es) | 2009-01-16 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: ZILA HEALTH PRODUCTS CO., LTD. Free format text: FORMER OWNER: OXYCAL LABORATORIES, INC. Effective date: 20061013 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20061013 Address after: Arizona, USA Patentee after: Auskos Lab Co., Ltd Address before: Arizona, USA Patentee before: Oxycal Laboratories Inc. |
|
C56 | Change in the name or address of the patentee |
Owner name: ETHOS C CO. Free format text: FORMER NAME OR ADDRESS: ZILA HEALTH PRODUCTS CO., LTD. |
|
CP03 | Change of name, title or address |
Address after: Arizona, USA Patentee after: Easy C Stewart Address before: Arizona, USA Patentee before: Auskos Lab Co., Ltd |
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C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040908 Termination date: 20100830 |