CN1143326A - 注射液体或药物用的导管 - Google Patents
注射液体或药物用的导管 Download PDFInfo
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- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0082—Catheter tip comprising a tool
- A61M25/0084—Catheter tip comprising a tool being one or more injection needles
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Abstract
一种注射导管,其中,或者是注射针束可以相对于导管杆移动,或者在导管尖端与导管杆固牢的情况下,注射针束可以沿纵向移动。为此,导管尖端可以取不同形式,导管杆内的注射针可以取不同形式并可以不同方式导引。一个操作装置用于实现注射针和导管尖端之间的相对移动,该操作装置包括可以可控地相对移动的两个部件,由此使注射针伸出或缩回。操作装置也包括能够通过注射针注射药物的入口。
Description
本发明涉及一种用于将液体或药物注射到空腔器官和体腔内特别是冠状血管和动脉内的导管,包括:一个可插入动脉的导管尖端;一个导管杆;多个配置在导管尖端内可移动的注射针,这些注射针的针尖在缩回位置时位于导管尖端内部而在伸出位置时从导管尖端凸出以便注射上述液体或药物;一个连接在导管的体外端部上使针尖通过导管杆移动的操作装置;以及在导管尖端中形成的允许注射针向侧面和向前凸出的开孔;其中,注射针固定在可在导管杆内纵向移动的软管上;上述导管杆固定在操作装置的一部分上而注射针固定在其另一部分上,使得两部分彼此相向的相对移动产生导管尖端和注射针彼此相对地移动,从而使注射针从上述缩回位置移动到上述伸出位置。
美国专利No.3,598,119公开了一种用于分配麻醉剂的医疗器械,其中一根注射针在同轴内腔中受到导引以便将针插在皮下,而一个在远端区域的气囊可以通过同轴外腔而膨胀,以便将针尖固定在皮下的位置中。
德国实用新型No.G89 13 761公开了一种纤维蛋白凝集素用的内窥镜注射装置,其中三根同轴管设有一个导入装置,外边的一根管用作两根内管的导向件,两根内管用于导入一种双组分纤维蛋白凝集素,它们在管的远端区域中混合后,通过一根连接在同轴管之一上的注射针而注射。
WO92 10 142公开了一种包括多腔导管杆的导管,其中可以使针沿纵向移动而通过导管尖端中的开孔伸出,并由此将针插入周围的组织中,以便在其中通过针引入纤维光学元件或测热元件,随情况而定。此外,这些中空的针适用于插入冲洗和抽吸用具。
美国专利No.4,578,061公开了一种用于将液体通过可以伸出的注射针注射到静脉或动脉中的导管,注射针可以在导管的前端沿纵向移动并与导管的轴向腔连通,因此,当它伸出时,从轴向腔接受供给它的药物。在导管尖端内设置一个双室系统,该系统包括两个同轴柱塞,一个柱塞可以在另一个柱塞中套筒式地移动,该双室系统使柱塞之一能够用于伸出注射针,并使另一柱塞能够用于通过该注射针注射预定剂量的药物。
PCT/EP93/02,829公开了一种此处最初提到的那种类型的导管。这种导管使用多根可以沿纵向在多腔杆中移动的注射针,多腔杆通过在其上插接和粘结的套管连接到导管尖端上。
因为治疗冠状血管和动脉的导管必须相当长,通常可以是约1.2m至1.6m长,所以如果多腔杆的各个腔中的多根注射针必须移动导管的全长度,那么就会产生相当大的摩擦。如果使用由塑料制成的多腔管,那么在这样长的长度上产生的此种相当高的摩擦也可能产生不希望有的沿纵向的伸长或压缩,使注射针难以在组织内精确地定位。
本发明的任务是排除这些缺点。
为解决上述任务,本发明规定,注射针通过粘结或套上一软管而成一束并可相对于导管头部移动。
因此,可分别根据导管头部或注射针束的设计可按有利的方式大大减少表面摩擦,由此能够将注射针在组织内精确定位。
在本发明的一个特定结构中,将注射针束在导管远端区域之后插入一个内径较大的挠性管中并可与该管一起在导管杆中移动。这种结构具有下列优点,就是只有两个彼此相对地同轴移动的管状腔,由于它们的结构形式,不管它们是由合适的塑料或金属制成都不会遭受不希望有的纵向伸长或压缩,因此,由于这两个两轴腔之间的小的摩擦,能够用很小的力就使注射针适宜,地定位。同时规定,注射针束在导管头部和同轴腔之间以成束形式延伸一段长度,从而由于成束的注射针的良好挠性而保证该导管远端区段的高度挠性。
为了更加增大导管远端的挠性,单个注射针最好具有较薄的壁但直径相同的流通容积,以便有更薄从而更有挠性的注射针。注射针的厚壁部分或者可以通过一个管状外杆延伸其整个长度,或者可以在一个一直到操作装置形成较大直径的流通容积的管状内腔中被粘结或焊接。这将形成对注射针的显著的过量供给液体,因此将能够均匀地注射液体。
根据本发明的又一个结构形式,导管杆内可以有一个模制的优质钢丝网,或者在导管杆或多腔束内可以分别安装一根稳定金属线,以便克服不希望有的纵向伸长或压缩而提高稳定性。
为了便于该导管的定位或定向导引,可以设置一根导向金属线,在一个被注射针束包围的导向腔中受到导引。该导向腔也可以偏心地安置在针束和导管外杆之间,使导向金属线在体外在操作装置前头引出。如果导管没有导向腔,可以将一根导向金属线固定在导管尖端的远端上。
在本发明的又一结构形式中,在整个导管长度上产生极小摩擦,其中,注射针束固定在导管杆上,或应用多腔杆而将注射针固定在各个腔内,其中,通过一个在导管杆中的导向腔延伸的一根操作金属线分别使导管尖端缩回导管杆中或从导管杆伸出。为了尽可能减小在导管尖端内导引注射针过程中产生的摩擦,该导管尖端包括一束形成腔的优质钢管,通过它们伸出注射针,如果需要,还伸出导向金属线。这种类型的导管尖端特别适用于预先弯曲的注射针或用超弹性的材料和/或具有形状记忆性能的材料制成的针。通过一个在导管尖端中形成的中心孔插入注射针束和使注射针沿侧向通过与中心孔连通的导向槽伸出也可以获得在导管尖端内导引注射针的一种特别有利的方式。
显然,如果导管尖端中有多个导向腔,并非所有这些腔都必须被注射针占据。相反,一些腔可以用于装入光导材料,用于通过导管将光能传导给组织,以便在应用光敏物质时导入所需的光能。或者它们可以用于插入控制和/或测量系统。在这种结构形式中,操作装置必须适当地改变,以便使为光导材料所设的腔通过操作装置能直接触及。但是,也允许导向腔的终点设在体外操作装置前,以便能够将这类光导材料或一根导向金属线插入导管。
这类导管用的操作装置包括注射针或操作金属线用的一个推力柱塞,该推力柱塞有一个螺纹部分,为轴向移动而设有一滚花螺母,该操作装置设有与单个注射针对应的药物入口。但是,也可以给操作装置提供合适的驱动机构而用气动、液动或电动方式来控制推力柱塞的进给移动。也可以规定用脚操作推力柱塞。如果操作装置设有几个药物入口,那么此种非手动类型的推力柱塞驱动特别有利。最好是,操作装置设有刻度,使得可以密切控制推力柱塞的移动。可以设置止动件以限制推力柱塞的移动。
对于特殊用途,注射导管可以在其上相对于导管尖端在远处和/或也在近处连接一个气囊,用于在注射期间固定导管,也可以连接一个血管成形术用的气囊,使得在注射的同时完成扩张。
注射针腔可以用于插入控制和测量用具。此类用具可以包括(例如)血管显微镜、超声测量装置、分光镜、测量活性和浓度和pH值的装置、温度计等等。当然,注射导管也可以通过穿刺管用于治疗(例如)肿瘤、转移瘤、炎症部位、脑回等等。
从下面结合权利要求和附图对优选实施例的说明中可以清楚本发明的其它优点和特点。
图1表示一种可在导管轴中移动的导管尖端,用以对安装于导管杆的几个腔中的注射针束作导引而缩回和伸出;
图2表示一种导管尖端与以成束形式安装在单腔杆中的缩回的注射针;
图3表示一种固定在单腔杆上的导管尖端,具有一个在单腔杆中可移动的挠性管,挠性管中固定了一束在导管尖端中可移动的注射针;
图4表示一种由一束管组成并固定在单腔杆上的导管尖端,单腔杆有一束可以通过其中移动的注射针;
图5表示一个用于在单腔杆中移动一束注射针的操作装置;
图6是由一束管组成的导管尖端沿图4中VI-VI线截取的截面图;
图7表示导管尖端的另一个实施例;
图8是一个包含针和导向腔的导管杆的截面图。
图1例示导管的远端结构,包括一个可以在固定套12中沿轴向移动的导管尖端11,固定套12连接在多腔杆14上,其中在各个腔内固定有注射针15。固定在导管尖端11上的操作金属线17在中心导向腔16内受到导向,导管尖端11可以利用该操作金属线17沿轴向移动。在图1所示的导管尖端的缩回位置,通过纵向导向槽18而使注射针15向外伸出,在该位置中针可以刺破围绕导管的组织。最好是,注射针有一定的弯曲,从而容易地在导向槽中向外伸出。针最好用优质钢或特殊合金制成,使它们具有足够的挠性和刚性,可以通过导管尖端的作用而向外伸出,但仍使它们坚韧到足以刺入组织。使用合适地磨光的针可以最佳地刺入组织。
图2例示导管的一种改型的远端结构20,表示导管尖端11向前移动到一个伸出位置,在该位置中注射针15完全位于导向槽18中。这是将导管插入动脉或静脉中的位置,通过一个连接在导管前端上所谓固定线的导引线19可使导管的插入更为方便。在图2所示的导管中,注射针15组合为一束,并就这样固定在单腔杆22上。操作金属线17通过注射针束的内部,并由其导引。操作金属线固定在导管尖端11上,因此,可以通过轴向移动操作金属线17而使导管尖端从导管远端部分中伸出或缩回。
图3例示本发明的又一个结构形式,其中,注射针束15可在单腔杆14内沿轴向移动,而导管尖端11借助于单腔杆14上的固定套12保持在不可移动的位置。挠性管24安置在单腔杆14内,在挠性管24的前端粘结或焊接有注射针15的后部,因此挠性管24在单腔杆14内沿轴向移动将使注射针相应地缩回导管尖端11或从导管尖端11中伸出。为了使远端结构具有高度挠性,导管尖端11和挠性管24之间的距离可以显著地大于图3中所示,这意味着,与图示的不同,固定套12并不延伸到可在其中移动挠性管24的区域。为了改善滑动性能,挠性管24最好涂有减摩材料,如PTFE(聚四氟乙烯)。该同一材料也用于可在图1所示的多腔杆和图2所示的单腔杆中移动的注射针。
图4表示本发明的再一个实施例,其中导管的远端40包括一个由一束管41组成的导管尖端,其横截面由图6表示。预先弯曲的注射针在一束管的各个管内延伸至单腔管22,该单腔管22通过固定套12与导管尖端牢固连接。注射针45在导管尖端和单腔杆22区域中的直径比在导管其余部分中的直径小,这使注射针的前端高度挠性而同时在导管杆的区域中保证最佳的刚性和挠性。可以滑动地支承在单腔杆22中的注射针最好涂有合适的减摩材料。在注射针束45的中心最好形成一腔以容纳导向金属线43,后者可通过导管尖端的管束内的一根相应的管子而向前伸出。为了减少内部摩擦并使得能够以较低压力注射药物,注射针45的具有较大外径的部分也可以具有比针尖内径大的内径。虽然图4描画的注射针的直径较大区段同样距导管尖端一个相当短的距离。为了有利于增加导管尖端处的挠性,这些针的较粗区段应当最好距固定套12一个较大的距离。
可以使用一操作装置来轴向移动注射针,如图5所示。该操作装置主要包括两个部件54和55,其中,54为静止部件和55为可动部件。可动部件55包括一个可在针筒57中滑动的推力柱塞56并在其上连接注射针的体外端部,该端部通过孔58与药物入口59相连通。可动部件55还包括一个孔60,该孔伸入导管杆内部的导引容积中。推力柱塞56具有螺纹,与滚花螺母62螺纹啮合,滚花螺母62栓住地支承在静止部件54上,并可以转动而移动在针筒57内的推力柱塞,并由此使与其连接的注射针相应地移动。针筒57可以设置刻度65,而推力柱塞56有一根指示线66,用于指示柱塞位移程度,并由此可以精确地控制柱塞位移。针筒57上连接导管杆22,后者可以有一个联结于其中的优质钢丝网52,用于在注射针位移时克服不希望有的纵向伸长和压缩而稳定导管杆22。图中例示的操作装置特别适用于一种具有图4所述的远端结构的导管。
在具有如图3所示的远端结构的导管中,连接在推力柱塞56上的是挠性管24而不是一束注射针,而且将仅提供一个药物入口59,该入口59与挠性管24内部连通。
对于具有如图1或2中所示的远端结构的导管,注射针的体外端部与操作装置50的静止部分相连,该静止部件设有相应的药物入口。操作装置的可动部件55作用在操作金属线17上,以实现在远端的导管尖端11纵向移动。
虽然图中没有示出,但导向金属线用的导向腔可以使其出口不是安置在操作装置上,而是在操作装置前面在导管杆的体外区域中,为此目的该导向腔偏心地配置在注射针束和外杆之间。
其次,导管杆上可以连接一根稳定金属线,该金属丝或者可以模制在导管杆的外壳中,或者,在导管杆是一个多腔杆时可以粘结在腔内。在图8的具有单腔杆的导管的截面图中,作为例子示出导向金属线和稳定金属线用的两个腔,它们模制在该杆的周边壁部分中,而注射针束被安置在杆内,可自由移动。
导管尖端可以用不同材料制成,塑料、金属、陶瓷或玻璃,结构设计最好是不透射伦琴射线的。
其次,可在导管内移动的腔最好在导管内受到密封以防止液体回流,例如利用合适的润滑剂。
为了稳定导管杆,和为了保证注射针从导管尖端平滑伸出,可以使导管杆扭动或注射针束可以在导管杆内沿一根细长的螺旋线配置。由此改进可移动性,特别是与减少摩擦的润滑剂结合使用。
注射导管的功能操作可以通过已提议的方式在导管上安装气囊而得到优化。该气囊在注射期间固定导管。相对于导管尖端在远处以及在近处配置的血管成形术用的气囊也将改善导管的应用性能,特别是,可以帮助在将药物注射到受感染的组织内的同时完成气囊的扩张。
Claims (12)
1.用于将液体或药物注射到空腔器官和体腔内特别是冠状血管和动脉内的导管,包括:一个适合于插入动脉的导管尖端;一个导管杆;多个可移动地安置在导管尖端内的注射针,这些注射针的针尖在缩回位置时位于导管尖端内部而在伸出位置时伸出导管尖端以便注射上述液体或药物;一个安置在导管的体外端部上的操作装置;以及在导管尖端中形成的允许针尖从其中向侧面和向前伸出的开孔;其中,注射针固定在可在导管内纵向移动的管上,该管被设计成可在导管杆内移动,而上述导管杆固定在操作装置的一部分上而注射针固定在其另一部分上,在上述两部分相对移动时,由于导管尖端和注射针之间的相应相对移动,而使一个或几个注射针从缩回位置移至伸出位置,其特征在于,注射针(15;45)通过套上一管而合并为一束针并可以相对导管尖端移动。
2.如权利要求1所述的导管,其特征在于,合并成一束的注射针(15;45)在导管的远端区域之后被插入内径较大的挠性管(24),并与管(24)一起可在导管杆(14,22)内移动。
3.如权利要求1或2所述的导管,其特征在于,注射针(15;45)在其远端区域内具有减小的壁厚度但相同的流动横截面。
4.如权利要求1至3中之一所述的导管,其特征在于,一个导向金属线(43)在被限定于上述注射针束之内的一个导向腔(60)中受到导向。
5.如权利要求4所述的导管,其特征在于,上述导向腔(60)在上述针束和导管杆之间偏心地延伸,并在操作装置(50)前的一个体外位置上向外敞开。
6.如权利要求1所述的导管,其特征在于,在该导管尖端(11,41)的远端固定有一个导向线(19)。
7.如权利要求1~6中之一或多项所述的导管,其特征在于,成束注射针(15)固定在导管杆内,一根操作金属线(17)延伸通过导管杆内的导向腔(60),用于使导管尖端(11)缩回到导管杆中和从导管杆中伸出。
8.如权利要求1~7中之一或几项所述的导管,其特征在于,导管尖端(41)包括一束优质钢管,注射针(45)和在必要时一导向金属线(43)延伸过该束钢管的空腔。
9.如权利要求1~8中之所述的导管,其特征在于,该束注射针(15)插入通过导管尖端(31)中的中心孔(32),并通过与该中心孔相连的导向槽向侧向伸出。
10.如权利要求1~9中之一或几项所述的导管,其特征在于,该导管杆有一个在其中模制的优质钢丝网。
11.如权利要求1~10中之一或几项所述的导管,其特征在于,上述导管杆内或上述多腔束安装一根稳定金属线(67)。
12.如权利要求1~11中之一或几项所述的导管,其特征在于,上述操作装置(50)具有一个推力柱塞(56),用于移动注射针(15)或上述操作金属线(17),设有螺纹(61)的上述推力柱塞(56),为了轴向移动而设有一个滚花螺母(62),在上述操作装置中设有与单个注射针(15)连通的药物入口(59)。
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DE4408108A DE4408108A1 (de) | 1994-03-10 | 1994-03-10 | Katheter zur Injektion eines Fluid bzw. eines Arneimittelns |
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---|---|---|---|---|
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CN103096965A (zh) * | 2010-09-10 | 2013-05-08 | 世运医药株式会社 | 包括引导线的导管组件 |
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Families Citing this family (376)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5707362A (en) * | 1992-04-15 | 1998-01-13 | Yoon; Inbae | Penetrating instrument having an expandable anchoring portion for triggering protrusion of a safety member and/or retraction of a penetrating member |
US6152141A (en) * | 1994-07-28 | 2000-11-28 | Heartport, Inc. | Method for delivery of therapeutic agents to the heart |
US5454782A (en) * | 1994-08-11 | 1995-10-03 | Perkins; Rodney C. | Translumenal circumferential energy delivery device |
US7867222B1 (en) | 1995-03-17 | 2011-01-11 | Tilton Jr Eugene B | Instrumentation for endoscopic surgical insertion and application of liquid, gel and like material |
US6010495A (en) * | 1995-03-17 | 2000-01-04 | Tilton, Jr.; Eugene B. | Instrumentation for endoscopic surgical insertion and application of liquid, gel and like material |
US6416506B1 (en) | 1995-03-17 | 2002-07-09 | Eugene B. Tilton, Jr. | Instrumentation for endoscopic surgical insertion and application of liquid, gel and like material |
US5797899A (en) * | 1995-03-17 | 1998-08-25 | Tilton, Jr.; Eugene B. | Instrumentation for laparoscopic surgical endoscopic insertion and application of liquid, gel and like material |
WO1996029943A1 (en) * | 1995-03-28 | 1996-10-03 | Eli Lilly And Company | Photodynamic therapy system and method |
US6322548B1 (en) | 1995-05-10 | 2001-11-27 | Eclipse Surgical Technologies | Delivery catheter system for heart chamber |
WO1996035464A1 (en) * | 1995-05-12 | 1996-11-14 | Perkins Rodney C | Translumenal circumferential injector |
US5693029A (en) * | 1995-07-10 | 1997-12-02 | World Medical Manufacturing Corporation | Pro-cell intra-cavity therapeutic agent delivery device |
EP1317908B1 (en) | 1995-10-13 | 2011-07-06 | Medtronic Vascular, Inc. | A device and system for interstitial transvascular intervention |
US6302875B1 (en) | 1996-10-11 | 2001-10-16 | Transvascular, Inc. | Catheters and related devices for forming passageways between blood vessels or other anatomical structures |
US6283951B1 (en) | 1996-10-11 | 2001-09-04 | Transvascular, Inc. | Systems and methods for delivering drugs to selected locations within the body |
AUPN775296A0 (en) * | 1996-01-25 | 1996-02-22 | Endogad Research Pty Limited | Directional catheter |
AU706522B2 (en) * | 1996-01-25 | 1999-06-17 | Endogad Research Pty Limited | Directional catheter |
US5814065A (en) * | 1996-02-09 | 1998-09-29 | Cordis Corporation | Suture delivery tool |
US5817069A (en) * | 1996-02-28 | 1998-10-06 | Vadus, Inc. | Valve assembly |
US5651772A (en) * | 1996-02-28 | 1997-07-29 | Aeroquip Corporation | Needle guard assembly |
EP0818899A1 (en) * | 1996-07-09 | 1998-01-14 | Alcatel Bell N.V. | Log-in method for a telecommunication network, main station and terminal station adapted to perform the method |
US5725503A (en) * | 1996-08-07 | 1998-03-10 | Aeroquip Corporation | Ratcheting needle protector assembly |
WO1998005375A1 (en) * | 1996-08-07 | 1998-02-12 | Vadus, Inc. | Needle protector |
DE19634866A1 (de) * | 1996-08-28 | 1998-03-05 | Bavaria Med Tech | Katheter zur Injektion und/oder Applikation eines Fluids |
EP0928208A4 (en) * | 1996-09-24 | 2000-10-18 | Synechion Tilton Joint Venture | DEVICE THAT CAN BE INSERTED INTO THE ABDOMEN TO APPLY A LIQUID, GEL OR RELATED MEDICAL SUBSTANCE |
US6051008A (en) | 1996-12-02 | 2000-04-18 | Angiotrax, Inc. | Apparatus having stabilization members for percutaneously performing surgery and methods of use |
US6102926A (en) * | 1996-12-02 | 2000-08-15 | Angiotrax, Inc. | Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use |
US6120520A (en) | 1997-05-27 | 2000-09-19 | Angiotrax, Inc. | Apparatus and methods for stimulating revascularization and/or tissue growth |
US6080137A (en) * | 1997-01-08 | 2000-06-27 | Vadus, Inc. | Needle protector |
US5954698A (en) | 1997-01-08 | 1999-09-21 | Vadus, Inc. | Catheter apparatus having valved catheter hub and needle protector |
US5882332A (en) * | 1997-06-06 | 1999-03-16 | Wijay; Bandula | Drug infusion catheter and method |
US6045528A (en) * | 1997-06-13 | 2000-04-04 | Intraear, Inc. | Inner ear fluid transfer and diagnostic system |
US6004295A (en) * | 1997-06-26 | 1999-12-21 | An-Go-Gen Inc. | Catheters |
JP2002512552A (ja) * | 1997-07-22 | 2002-04-23 | イーメッド コーポレイション | 心臓組織中への薬剤のイオン電気導入法による配送 |
GB2327614B (en) * | 1997-07-30 | 2002-03-06 | Univ Dundee | A hypodermic needle |
US6623473B1 (en) | 1998-06-04 | 2003-09-23 | Biosense Webster, Inc. | Injection catheter with multi-directional delivery injection needle |
US8079982B1 (en) | 1998-06-04 | 2011-12-20 | Biosense Webster, Inc. | Injection catheter with needle electrode |
US6623474B1 (en) | 1998-06-04 | 2003-09-23 | Biosense Webster, Inc. | Injection catheter with needle stop |
CA2273467C (en) * | 1998-06-04 | 2009-02-17 | Cordis Webster, Inc. | Catheter for injecting therapeutic and diagnostic agents |
US6540725B1 (en) * | 1998-06-04 | 2003-04-01 | Biosense Webster, Inc. | Injection catheter with controllably extendable injection needle |
US6575931B1 (en) | 1998-06-04 | 2003-06-10 | Biosense Webster, Inc. | Catheter with injection needle |
US7416547B2 (en) * | 1999-03-29 | 2008-08-26 | Biosense Webster Inc. | Injection catheter |
US6905476B2 (en) * | 1998-06-04 | 2005-06-14 | Biosense Webster, Inc. | Catheter with injection needle |
US6165164A (en) * | 1999-03-29 | 2000-12-26 | Cordis Corporation | Catheter for injecting therapeutic and diagnostic agents |
US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
US6309374B1 (en) * | 1998-08-03 | 2001-10-30 | Insite Vision Incorporated | Injection apparatus and method of using same |
US6129713A (en) * | 1998-08-11 | 2000-10-10 | Embol-X, Inc. | Slidable cannula and method of use |
US6048332A (en) * | 1998-10-09 | 2000-04-11 | Ave Connaught | Dimpled porous infusion balloon |
WO2000033909A1 (en) | 1998-12-09 | 2000-06-15 | Cook Incorporated | Hollow, curved, superelastic medical needle |
DE69917484T2 (de) * | 1998-12-14 | 2005-05-12 | Tre Esse Progettazione Biomedica S.R.L. | Kathetersystem zur durchführung einer intramyokardialen therapeutischen behandlung |
WO2000040281A1 (en) * | 1999-01-06 | 2000-07-13 | United States Surgical Corporation | Tissue mapping injection device |
US6217554B1 (en) | 1999-02-12 | 2001-04-17 | Pharmaspec Corporation | Methods and apparatus for delivering substances into extravascular tissue |
US6398758B1 (en) | 1999-02-16 | 2002-06-04 | Stephen C. Jacobsen | Medicament delivery system |
US6685913B1 (en) * | 1999-03-09 | 2004-02-03 | Thomas Jefferson University | Lipid soluble radioactive metal chelates for tumor therapy |
US6302870B1 (en) * | 1999-04-29 | 2001-10-16 | Precision Vascular Systems, Inc. | Apparatus for injecting fluids into the walls of blood vessels, body cavities, and the like |
US6319230B1 (en) * | 1999-05-07 | 2001-11-20 | Scimed Life Systems, Inc. | Lateral needle injection apparatus and method |
US6689103B1 (en) | 1999-05-07 | 2004-02-10 | Scimed Life System, Inc. | Injection array apparatus and method |
WO2000072908A1 (en) * | 1999-06-02 | 2000-12-07 | Microheart, Inc. | Devices and methods for delivering a drug |
US7147633B2 (en) * | 1999-06-02 | 2006-12-12 | Boston Scientific Scimed, Inc. | Method and apparatus for treatment of atrial fibrillation |
US6283947B1 (en) | 1999-07-13 | 2001-09-04 | Advanced Cardiovascular Systems, Inc. | Local drug delivery injection catheter |
US6494862B1 (en) * | 1999-07-13 | 2002-12-17 | Advanced Cardiovascular Systems, Inc. | Substance delivery apparatus and a method of delivering a therapeutic substance to an anatomical passageway |
US6629987B1 (en) * | 1999-07-30 | 2003-10-07 | C. R. Bard, Inc. | Catheter positioning systems |
US6676679B1 (en) | 1999-11-05 | 2004-01-13 | Boston Scientific Corporation | Method and apparatus for recurrent demand injury in stimulating angiogenesis |
US6748258B1 (en) * | 1999-11-05 | 2004-06-08 | Scimed Life Systems, Inc. | Method and devices for heart treatment |
WO2001032088A2 (en) * | 1999-11-05 | 2001-05-10 | Microheart, Inc. | Method and apparatus for demand injury in stimulating angiogenesis |
JP4566390B2 (ja) | 1999-11-12 | 2010-10-20 | バイオセンス・ウエブスター・インコーポレーテツド | 注入カテーテル |
US6613026B1 (en) * | 1999-12-08 | 2003-09-02 | Scimed Life Systems, Inc. | Lateral needle-less injection apparatus and method |
US6344027B1 (en) | 1999-12-08 | 2002-02-05 | Scimed Life Systems, Inc. | Needle-less injection apparatus and method |
US6461364B1 (en) | 2000-01-05 | 2002-10-08 | Integrated Vascular Systems, Inc. | Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use |
US6942674B2 (en) | 2000-01-05 | 2005-09-13 | Integrated Vascular Systems, Inc. | Apparatus and methods for delivering a closure device |
US7842068B2 (en) | 2000-12-07 | 2010-11-30 | Integrated Vascular Systems, Inc. | Apparatus and methods for providing tactile feedback while delivering a closure device |
US9579091B2 (en) | 2000-01-05 | 2017-02-28 | Integrated Vascular Systems, Inc. | Closure system and methods of use |
US6391048B1 (en) | 2000-01-05 | 2002-05-21 | Integrated Vascular Systems, Inc. | Integrated vascular device with puncture site closure component and sealant and methods of use |
US8758400B2 (en) | 2000-01-05 | 2014-06-24 | Integrated Vascular Systems, Inc. | Closure system and methods of use |
US20010034501A1 (en) * | 2000-03-23 | 2001-10-25 | Tom Curtis P. | Pressure sensor for therapeutic delivery device and method |
US7214223B2 (en) * | 2000-03-24 | 2007-05-08 | Boston Scientific Scimed, Inc. | Photoatherolytic catheter apparatus and method |
US20050277887A1 (en) * | 2000-05-08 | 2005-12-15 | Joel Douglas | Micro infusion drug delivery device |
US6659982B2 (en) * | 2000-05-08 | 2003-12-09 | Sterling Medivations, Inc. | Micro infusion drug delivery device |
WO2002000278A2 (en) | 2000-06-26 | 2002-01-03 | Microheart, Inc. | Method and apparatus for treating ischemic tissue |
EP1301228B1 (en) * | 2000-07-13 | 2008-07-23 | Abbott Cardiovascular Systems Inc. | Deployment system for myocardial cellular material |
SE516673C2 (sv) * | 2000-07-27 | 2002-02-12 | Q Med Ab | Arrangemang och förfarande för samverkan med ett inre kroppsorgan |
DE60128355T2 (de) | 2000-09-08 | 2008-01-10 | Abbott Vascular Inc., Redwood City | Chirurgisches klammergerät |
US6626918B1 (en) | 2000-10-06 | 2003-09-30 | Medical Technology Group | Apparatus and methods for positioning a vascular sheath |
ATE296057T1 (de) * | 2000-11-24 | 2005-06-15 | Innovacell Biotechnologie Gmbh | Ultraschallsonde mit positioniereinrichtung für untersuchungs- und operationsvorrichtungen |
US7211101B2 (en) | 2000-12-07 | 2007-05-01 | Abbott Vascular Devices | Methods for manufacturing a clip and clip |
US7905900B2 (en) | 2003-01-30 | 2011-03-15 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US6695867B2 (en) | 2002-02-21 | 2004-02-24 | Integrated Vascular Systems, Inc. | Plunger apparatus and methods for delivering a closure device |
US7806904B2 (en) | 2000-12-07 | 2010-10-05 | Integrated Vascular Systems, Inc. | Closure device |
US8690910B2 (en) | 2000-12-07 | 2014-04-08 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US6623510B2 (en) | 2000-12-07 | 2003-09-23 | Integrated Vascular Systems, Inc. | Closure device and methods for making and using them |
US6599267B1 (en) * | 2000-12-22 | 2003-07-29 | Advanced Cardiovascular Systems, Inc. | Transluminal injection device for intravascular drug delivery |
US7481790B2 (en) * | 2000-12-27 | 2009-01-27 | Advanced Cardiovascular Systems, Inc. | Vessel enlargement by arteriogenic factor delivery |
US6989004B2 (en) * | 2001-02-28 | 2006-01-24 | Rex Medical, L.P. | Apparatus for delivering ablation fluid to treat lesions |
JP4588977B2 (ja) * | 2001-02-28 | 2010-12-01 | レックス メディカル リミテッド パートナーシップ | 新生物を治療するアブレーション液を供給するための装置 |
US7087040B2 (en) | 2001-02-28 | 2006-08-08 | Rex Medical, L.P. | Apparatus for delivering ablation fluid to treat lesions |
IES20010547A2 (en) | 2001-06-07 | 2002-12-11 | Christy Cummins | Surgical Staple |
US7311698B2 (en) | 2001-09-24 | 2007-12-25 | Coloplast A/S | Urinary catheter assembly allowing for non-contaminated insertion of the catheter into a urinary canal |
CA2451344A1 (en) | 2001-06-29 | 2003-01-09 | Coloplast A/S | A bag for collection of bodily fluids |
US7682353B2 (en) | 2001-06-29 | 2010-03-23 | Coloplast A/S | Catheter device |
US6835193B2 (en) * | 2001-07-10 | 2004-12-28 | Myocardial Therapeutics, Inc. | Methods for controlled depth injections into interior body cavities |
US6916328B2 (en) * | 2001-11-15 | 2005-07-12 | Expanding Concepts, L.L.C | Percutaneous cellulite removal system |
JP4229621B2 (ja) * | 2002-03-05 | 2009-02-25 | 修 加藤 | 薬液注入カテーテル |
US9636174B2 (en) | 2002-04-08 | 2017-05-02 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US7141041B2 (en) * | 2003-03-19 | 2006-11-28 | Mercator Medsystems, Inc. | Catheters having laterally deployable needles |
IES20030424A2 (en) | 2002-06-04 | 2003-12-10 | Robert Stevenson | Blood vessel closure clip and delivery device |
US7364567B2 (en) | 2002-06-10 | 2008-04-29 | Abbott Cardiovascular Systems Inc. | Systems and methods for detecting tissue contact and needle penetration depth |
US8574195B2 (en) * | 2002-06-10 | 2013-11-05 | Advanced Cardiovascular Systems, Inc. | Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements |
US7361368B2 (en) | 2002-06-28 | 2008-04-22 | Advanced Cardiovascular Systems, Inc. | Device and method for combining a treatment agent and a gel |
US7931658B2 (en) | 2002-09-20 | 2011-04-26 | Interrad Medical, Inc. | Temporary retention device |
WO2004030718A2 (en) * | 2002-09-20 | 2004-04-15 | Flowmedica, Inc. | Method and apparatus for intra aortic substance delivery to a branch vessel |
US7108710B2 (en) * | 2002-11-26 | 2006-09-19 | Abbott Laboratories | Multi-element biased suture clip |
US8905937B2 (en) | 2009-02-26 | 2014-12-09 | Integrated Vascular Systems, Inc. | Methods and apparatus for locating a surface of a body lumen |
US8202293B2 (en) | 2003-01-30 | 2012-06-19 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US8821534B2 (en) | 2010-12-06 | 2014-09-02 | Integrated Vascular Systems, Inc. | Clip applier having improved hemostasis and methods of use |
US7857828B2 (en) | 2003-01-30 | 2010-12-28 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US8398656B2 (en) | 2003-01-30 | 2013-03-19 | Integrated Vascular Systems, Inc. | Clip applier and methods of use |
US8758398B2 (en) | 2006-09-08 | 2014-06-24 | Integrated Vascular Systems, Inc. | Apparatus and method for delivering a closure element |
JP4272905B2 (ja) * | 2003-03-06 | 2009-06-03 | 修 加藤 | 薬液注入装置 |
US7776005B2 (en) * | 2003-03-28 | 2010-08-17 | Covidien Ag | Triple lumen catheter with occlusion resistant tip |
US7090654B2 (en) * | 2003-03-28 | 2006-08-15 | Sherwood Services Ag | Catheter with occlusion resistant tip |
US7141035B2 (en) * | 2003-03-28 | 2006-11-28 | Sherwood Services Ag | Catheter with occlusion resistant tip |
US7641643B2 (en) | 2003-04-15 | 2010-01-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
US8821473B2 (en) | 2003-04-15 | 2014-09-02 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
JP4289919B2 (ja) * | 2003-05-06 | 2009-07-01 | 朝日インテック株式会社 | 薬液注入装置 |
JP4212949B2 (ja) * | 2003-05-06 | 2009-01-21 | 朝日インテック株式会社 | 薬液注入装置 |
US8308708B2 (en) * | 2003-07-15 | 2012-11-13 | Abbott Cardiovascular Systems Inc. | Deployment system for myocardial cellular material |
US7588557B2 (en) * | 2003-09-24 | 2009-09-15 | Granit-Medical Innovations, Llc | Medical instrument for fluid injection and related method |
US20050070874A1 (en) * | 2003-09-30 | 2005-03-31 | Hikaru Matsuda | System and method for injecting liquid drug containing biological material |
US20050101909A1 (en) * | 2003-11-07 | 2005-05-12 | Cino Rossi | Apparatus for topical innoculation of pharmaceuticals |
ES2289425T3 (es) * | 2004-04-20 | 2008-02-01 | Bandula Wijay | Cateter para la administracion local de un farmaco. |
CA2779044C (en) * | 2004-04-28 | 2014-12-16 | Conceptus, Inc. | Endoscopic delivery of medical devices |
IES20040368A2 (en) | 2004-05-25 | 2005-11-30 | James E Coleman | Surgical stapler |
DE102004026089A1 (de) * | 2004-05-25 | 2005-12-22 | Medizinische Hochschule Hannover | Katheter |
US7632262B2 (en) * | 2004-07-19 | 2009-12-15 | Nexeon Medical Systems, Inc. | Systems and methods for atraumatic implantation of bio-active agents |
GB0419653D0 (en) * | 2004-09-04 | 2004-10-06 | Psimedica Ltd | Needle assembly |
US7458971B2 (en) * | 2004-09-24 | 2008-12-02 | Boston Scientific Scimed, Inc. | RF ablation probe with unibody electrode element |
JP4821947B2 (ja) * | 2004-10-19 | 2011-11-24 | 朝日インテック株式会社 | 薬液注入装置 |
WO2006055288A2 (en) | 2004-11-04 | 2006-05-26 | Sherwood Service Ag | Catheter insertion apparatus |
WO2006055826A2 (en) | 2004-11-18 | 2006-05-26 | Chang David W | Endoluminal delivery of anesthesia |
US20060111704A1 (en) * | 2004-11-22 | 2006-05-25 | Rox Medical, Inc. | Devices, systems, and methods for energy assisted arterio-venous fistula creation |
US7803168B2 (en) | 2004-12-09 | 2010-09-28 | The Foundry, Llc | Aortic valve repair |
US7517338B2 (en) * | 2005-01-21 | 2009-04-14 | Boston Scientific Scimed, Inc. | Delivery of therapeutic through multiple delivery members |
US7431687B2 (en) | 2005-03-07 | 2008-10-07 | Boston Scientific Scimed, Inc. | Percutaneous array delivery system |
US7314462B2 (en) * | 2005-04-12 | 2008-01-01 | Span-America Medical Systems, Inc. | Passive needle-stick protector |
US9539410B2 (en) | 2005-04-19 | 2017-01-10 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating post-cardial infarction damage |
US20080125745A1 (en) * | 2005-04-19 | 2008-05-29 | Shubhayu Basu | Methods and compositions for treating post-cardial infarction damage |
US8828433B2 (en) * | 2005-04-19 | 2014-09-09 | Advanced Cardiovascular Systems, Inc. | Hydrogel bioscaffoldings and biomedical device coatings |
US8187621B2 (en) | 2005-04-19 | 2012-05-29 | Advanced Cardiovascular Systems, Inc. | Methods and compositions for treating post-myocardial infarction damage |
US10076641B2 (en) | 2005-05-11 | 2018-09-18 | The Spectranetics Corporation | Methods and systems for delivering substances into luminal walls |
EP1896112A4 (en) * | 2005-06-07 | 2011-04-27 | A M S Res Corp | INJECTION GUIDANCE SYSTEM AND METHOD |
US7691086B2 (en) * | 2005-06-14 | 2010-04-06 | Tengiz Tkebuchava | Catheter for introduction of medications to the tissues of a heart or other organ |
US8465451B2 (en) | 2005-06-22 | 2013-06-18 | Covidien Lp | Methods and apparatus for introducing tumescent fluid to body tissue |
US8926633B2 (en) | 2005-06-24 | 2015-01-06 | Abbott Laboratories | Apparatus and method for delivering a closure element |
US8313497B2 (en) | 2005-07-01 | 2012-11-20 | Abbott Laboratories | Clip applier and methods of use |
AU2006264300B2 (en) | 2005-07-06 | 2012-03-08 | Vascular Pathways Inc. | Intravenous catheter insertion device and method of use |
US8920442B2 (en) | 2005-08-24 | 2014-12-30 | Abbott Vascular Inc. | Vascular opening edge eversion methods and apparatuses |
US20070060895A1 (en) | 2005-08-24 | 2007-03-15 | Sibbitt Wilmer L Jr | Vascular closure methods and apparatuses |
US9456811B2 (en) | 2005-08-24 | 2016-10-04 | Abbott Vascular Inc. | Vascular closure methods and apparatuses |
US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US8518069B2 (en) | 2005-09-07 | 2013-08-27 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
JP4868387B2 (ja) * | 2005-09-21 | 2012-02-01 | 朝日インテック株式会社 | 薬液注入装置 |
ITFI20050216A1 (it) * | 2005-10-14 | 2007-04-15 | Elenor S R L | Strumento per agevolare l'anastomosi dell'uretra nella prostatectomia laparoscopica |
US20070100286A1 (en) * | 2005-11-01 | 2007-05-03 | Eltahawy Hazem A | Needle assembly for radiating bioactive compounds through tissue |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
US7885793B2 (en) | 2007-05-22 | 2011-02-08 | International Business Machines Corporation | Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution |
US20090292279A1 (en) * | 2006-01-26 | 2009-11-26 | Galil Medical Ltd. | Device and Method for Coordinated Insertion of a Plurality of Cryoprobes |
US8016794B2 (en) | 2006-03-09 | 2011-09-13 | Interrad Medical, Inc. | Anchor device and method |
US20070250035A1 (en) * | 2006-04-19 | 2007-10-25 | El-Nounou Fozan O | Devices and methods for intravascular drug delivery |
US8808310B2 (en) | 2006-04-20 | 2014-08-19 | Integrated Vascular Systems, Inc. | Resettable clip applier and reset tools |
US20070269385A1 (en) * | 2006-05-18 | 2007-11-22 | Mercator Medsystems, Inc | Devices, methods, and systems for delivering therapeutic agents for the treatment of sinusitis, rhinitis, and other disorders |
US20080004596A1 (en) * | 2006-05-25 | 2008-01-03 | Palo Alto Institute | Delivery of agents by microneedle catheter |
EP2029213A2 (en) * | 2006-06-14 | 2009-03-04 | Cornova, Inc. | Method and apparatus for identifying and treating myocardial infarction |
US8556930B2 (en) | 2006-06-28 | 2013-10-15 | Abbott Laboratories | Vessel closure device |
US7732190B2 (en) * | 2006-07-31 | 2010-06-08 | Advanced Cardiovascular Systems, Inc. | Modified two-component gelation systems, methods of use and methods of manufacture |
US9867530B2 (en) | 2006-08-14 | 2018-01-16 | Volcano Corporation | Telescopic side port catheter device with imaging system and method for accessing side branch occlusions |
US9242005B1 (en) | 2006-08-21 | 2016-01-26 | Abbott Cardiovascular Systems Inc. | Pro-healing agent formulation compositions, methods and treatments |
US20090012413A1 (en) * | 2006-09-08 | 2009-01-08 | Sabbah Hani N | Cardiac patterning for improving diastolic function |
US9782258B2 (en) * | 2006-09-08 | 2017-10-10 | The Regents Of The University Of California | Intramyocardial patterning for global cardiac resizing and reshaping |
US9005672B2 (en) * | 2006-11-17 | 2015-04-14 | Abbott Cardiovascular Systems Inc. | Methods of modifying myocardial infarction expansion |
US8741326B2 (en) | 2006-11-17 | 2014-06-03 | Abbott Cardiovascular Systems Inc. | Modified two-component gelation systems, methods of use and methods of manufacture |
US8192760B2 (en) | 2006-12-04 | 2012-06-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating tissue using silk proteins |
US8473030B2 (en) * | 2007-01-12 | 2013-06-25 | Medtronic Vascular, Inc. | Vessel position and configuration imaging apparatus and methods |
ATE489989T1 (de) | 2007-05-07 | 2010-12-15 | Vascular Pathways Inc | Einführung eines intravenösen katheters und blutentnahmevorrichtung und anwendungsverfahren |
US7658729B2 (en) * | 2007-05-25 | 2010-02-09 | Hull Thomas P | Attachment device and system for corneal irrigating cannula and method thereof |
US11859168B2 (en) | 2007-05-29 | 2024-01-02 | Christopher B. REID | Electroporation, developmentally-activated cells, pluripotent-like cells, cell reprogramming and regenerative medicine |
US9364586B2 (en) | 2007-05-31 | 2016-06-14 | Abbott Cardiovascular Systems Inc. | Method and apparatus for improving delivery of an agent to a kidney |
US8216209B2 (en) | 2007-05-31 | 2012-07-10 | Abbott Cardiovascular Systems Inc. | Method and apparatus for delivering an agent to a kidney |
US9144509B2 (en) | 2007-05-31 | 2015-09-29 | Abbott Cardiovascular Systems Inc. | Method and apparatus for delivering an agent to a kidney |
US9149610B2 (en) | 2007-05-31 | 2015-10-06 | Abbott Cardiovascular Systems Inc. | Method and apparatus for improving delivery of an agent to a kidney |
US8226681B2 (en) | 2007-06-25 | 2012-07-24 | Abbott Laboratories | Methods, devices, and apparatus for managing access through tissue |
US9596993B2 (en) | 2007-07-12 | 2017-03-21 | Volcano Corporation | Automatic calibration systems and methods of use |
WO2009009802A1 (en) | 2007-07-12 | 2009-01-15 | Volcano Corporation | Oct-ivus catheter for concurrent luminal imaging |
JP5524835B2 (ja) | 2007-07-12 | 2014-06-18 | ヴォルカノ コーポレイション | 生体内撮像用カテーテル |
US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
DE102007052513A1 (de) | 2007-10-26 | 2009-04-30 | Karl Storz Gmbh & Co. Kg | Medizinisches Instrument mit seitlich ausspreizbaren Injektionsnadeln |
US20090118673A1 (en) * | 2007-11-07 | 2009-05-07 | Jerett Creed | Needle injection catheter |
EP2065069A1 (en) | 2007-11-29 | 2009-06-03 | National University of Ireland Galway | A Catheter based Medical Device and Method for Delivery of a Therapeutic Agent |
US8893947B2 (en) | 2007-12-17 | 2014-11-25 | Abbott Laboratories | Clip applier and methods of use |
US20090157101A1 (en) | 2007-12-17 | 2009-06-18 | Abbott Laboratories | Tissue closure system and methods of use |
US7841502B2 (en) | 2007-12-18 | 2010-11-30 | Abbott Laboratories | Modular clip applier |
US7824377B2 (en) * | 2007-12-21 | 2010-11-02 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Tissue anchoring catheter systems and methods |
AU2009208930A1 (en) * | 2008-01-31 | 2009-08-06 | Proteon Therapeutics, Inc. | Medical device |
EP3251719B1 (en) * | 2008-02-05 | 2020-10-21 | Bridgepoint Medical, Inc. | Crossing occlusions in blood vessels |
US8801665B2 (en) * | 2008-04-10 | 2014-08-12 | Henry Ford Health System | Apparatus and method for controlled depth of injection into myocardial tissue |
US9282965B2 (en) | 2008-05-16 | 2016-03-15 | Abbott Laboratories | Apparatus and methods for engaging tissue |
US20090312617A1 (en) * | 2008-06-12 | 2009-12-17 | Jerett Creed | Needle injection catheter |
US8486022B2 (en) * | 2008-07-03 | 2013-07-16 | Abbott Cardiovascular Systems Inc. | Needle catheter with an angled distal tip lumen |
US8038653B2 (en) | 2008-07-16 | 2011-10-18 | Interrad Medical, Inc. | Anchor systems and methods |
RU2444976C2 (ru) * | 2008-07-21 | 2012-03-20 | Сергей Александрович Габриэль | Устройство для эндоскопических измерений опухолевых образований желудочно-кишечного тракта |
WO2010011930A2 (en) * | 2008-07-24 | 2010-01-28 | Boston Scientific Scimed, Inc. | Various catheter devices for myocardial injections or other uses |
EP2313148B1 (en) | 2008-07-30 | 2013-08-21 | Ecole Polytechnique Fédérale de Lausanne | Apparatus for optimized stimulation of a neurological target |
US20100069760A1 (en) * | 2008-09-17 | 2010-03-18 | Cornova, Inc. | Methods and apparatus for analyzing and locally treating a body lumen |
WO2010039862A1 (en) * | 2008-09-30 | 2010-04-08 | Rox Medical, Inc. | Methods for screening and treating patients with compromised cardiopulmonary function |
US9241696B2 (en) | 2008-10-30 | 2016-01-26 | Abbott Vascular Inc. | Closure device |
WO2010055421A1 (en) | 2008-11-12 | 2010-05-20 | Aleva Neurotherapeutics, S.A. | Microfabricated neurostimulation device |
US8858594B2 (en) | 2008-12-22 | 2014-10-14 | Abbott Laboratories | Curved closure device |
US8323312B2 (en) | 2008-12-22 | 2012-12-04 | Abbott Laboratories | Closure device |
US20100179589A1 (en) | 2009-01-09 | 2010-07-15 | Abbott Vascular Inc. | Rapidly eroding anchor |
US9486191B2 (en) | 2009-01-09 | 2016-11-08 | Abbott Vascular, Inc. | Closure devices |
US9414820B2 (en) | 2009-01-09 | 2016-08-16 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US9173644B2 (en) | 2009-01-09 | 2015-11-03 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US9089311B2 (en) | 2009-01-09 | 2015-07-28 | Abbott Vascular Inc. | Vessel closure devices and methods |
US20100185234A1 (en) | 2009-01-16 | 2010-07-22 | Abbott Vascular Inc. | Closure devices, systems, and methods |
US8328764B2 (en) | 2009-02-06 | 2012-12-11 | Interrad Medical, Inc. | System for anchoring medical devices |
BE1018521A5 (fr) * | 2009-04-29 | 2011-02-01 | Cardio3 Biosciences Sa | Catheter d'injection pour la delivrance d'un agent therapeutique dans un substrat. |
US20100292641A1 (en) * | 2009-05-15 | 2010-11-18 | Bandula Wijay | Targeted drug delivery device and method |
US8945060B2 (en) | 2009-06-05 | 2015-02-03 | Cook Medical Technologies Llc | Access sheath and needle assembly for delivering therapeutic material |
EP2445547B1 (en) | 2009-06-26 | 2017-08-02 | Covidien LP | Catheterization system |
US8298187B2 (en) | 2009-07-07 | 2012-10-30 | Cook Medical Technologies Llc | Fluid injection device |
US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
US20110054492A1 (en) | 2009-08-26 | 2011-03-03 | Abbott Laboratories | Medical device for repairing a fistula |
CA2715857A1 (en) | 2009-09-30 | 2011-03-30 | Tyco Healthcare Group Lp | Medical catheter having a design providing low recirculation and reversibility |
WO2011068874A2 (en) * | 2009-12-01 | 2011-06-09 | University Of South Florida | Drug delivery device for ovarian cancer |
EP2506920B1 (en) | 2009-12-01 | 2016-07-13 | Ecole Polytechnique Fédérale de Lausanne | Microfabricated surface neurostimulation device and method of making the same |
CA2792608C (en) * | 2010-03-10 | 2015-02-10 | The Cleveland Clinic Foundation | Catheter assembly |
US8303624B2 (en) | 2010-03-15 | 2012-11-06 | Abbott Cardiovascular Systems, Inc. | Bioabsorbable plug |
JP4679666B1 (ja) * | 2010-03-30 | 2011-04-27 | 日本ライフライン株式会社 | カテーテル |
CA2795159C (en) | 2010-04-01 | 2020-11-03 | Ecole Polytechnique Federale De Lausanne | Device for interacting with neurological tissue and methods of making and using the same |
EP2380604A1 (en) | 2010-04-19 | 2011-10-26 | InnoRa Gmbh | Improved coating formulations for scoring or cutting balloon catheters |
US10384039B2 (en) | 2010-05-14 | 2019-08-20 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US9872971B2 (en) | 2010-05-14 | 2018-01-23 | C. R. Bard, Inc. | Guidewire extension system for a catheter placement device |
US9950139B2 (en) | 2010-05-14 | 2018-04-24 | C. R. Bard, Inc. | Catheter placement device including guidewire and catheter control elements |
US11925779B2 (en) | 2010-05-14 | 2024-03-12 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US8932258B2 (en) | 2010-05-14 | 2015-01-13 | C. R. Bard, Inc. | Catheter placement device and method |
US8758399B2 (en) | 2010-08-02 | 2014-06-24 | Abbott Cardiovascular Systems, Inc. | Expandable bioabsorbable plug apparatus and method |
US8603116B2 (en) | 2010-08-04 | 2013-12-10 | Abbott Cardiovascular Systems, Inc. | Closure device with long tines |
WO2012038959A2 (en) * | 2010-09-21 | 2012-03-29 | Israel Shamir Lebovitz | Multi-directional needle |
JP2012065861A (ja) | 2010-09-24 | 2012-04-05 | Nihon Covidien Kk | 透析用カテーテル |
US11141063B2 (en) | 2010-12-23 | 2021-10-12 | Philips Image Guided Therapy Corporation | Integrated system architectures and methods of use |
US11040140B2 (en) | 2010-12-31 | 2021-06-22 | Philips Image Guided Therapy Corporation | Deep vein thrombosis therapeutic methods |
US20120226153A1 (en) | 2010-12-31 | 2012-09-06 | Volcano Corporation | Deep Vein Thrombosis Diagnostic Methods and Associated Devices and Systems |
US9943360B2 (en) * | 2011-01-30 | 2018-04-17 | University Health Network | Coil electrode for thermal therapy |
US8690833B2 (en) | 2011-01-31 | 2014-04-08 | Vascular Pathways, Inc. | Intravenous catheter and insertion device with reduced blood spatter |
US8617184B2 (en) | 2011-02-15 | 2013-12-31 | Abbott Cardiovascular Systems, Inc. | Vessel closure system |
EP2678065B1 (en) | 2011-02-25 | 2019-09-11 | C.R. Bard Inc. | Medical component insertion device including a retractable needle |
US9149276B2 (en) | 2011-03-21 | 2015-10-06 | Abbott Cardiovascular Systems, Inc. | Clip and deployment apparatus for tissue closure |
JP5759615B2 (ja) | 2011-04-08 | 2015-08-05 | コヴィディエン リミテッド パートナーシップ | 腎交感神経の除神経およびイオン導入薬物送達のためのイオン導入カテーテルシステムならびに方法 |
US8663190B2 (en) | 2011-04-22 | 2014-03-04 | Ablative Solutions, Inc. | Expandable catheter system for peri-ostial injection and muscle and nerve fiber ablation |
US9237925B2 (en) | 2011-04-22 | 2016-01-19 | Ablative Solutions, Inc. | Expandable catheter system for peri-ostial injection and muscle and nerve fiber ablation |
USD903101S1 (en) | 2011-05-13 | 2020-11-24 | C. R. Bard, Inc. | Catheter |
ES2660182T3 (es) * | 2011-06-06 | 2018-03-21 | The Cleveland Clinic Foundation | Conjunto de catéter |
US20130030478A1 (en) * | 2011-07-26 | 2013-01-31 | Rodriguez Jose A | Anchor wire system and method |
US9278196B2 (en) | 2011-08-24 | 2016-03-08 | Ablative Solutions, Inc. | Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation |
US20130053792A1 (en) | 2011-08-24 | 2013-02-28 | Ablative Solutions, Inc. | Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation |
US9056185B2 (en) | 2011-08-24 | 2015-06-16 | Ablative Solutions, Inc. | Expandable catheter system for fluid injection into and deep to the wall of a blood vessel |
US9585784B2 (en) | 2011-08-29 | 2017-03-07 | Coloplast A/S | Catheter activation by handle removal |
US9360630B2 (en) | 2011-08-31 | 2016-06-07 | Volcano Corporation | Optical-electrical rotary joint and methods of use |
US8747343B2 (en) | 2011-09-30 | 2014-06-10 | Covidien Lp | Hemodialysis catheter with improved side opening design |
US9072867B2 (en) | 2011-09-30 | 2015-07-07 | Covidien Lp | Catheter with external flow channel |
US9332976B2 (en) | 2011-11-30 | 2016-05-10 | Abbott Cardiovascular Systems, Inc. | Tissue closure device |
CA2801744C (en) * | 2012-01-17 | 2015-10-13 | Covidien Lp | Material removal device and method of use |
US10213187B1 (en) | 2012-01-25 | 2019-02-26 | Mubin I. Syed | Method and apparatus for percutaneous superficial temporal artery access for carotid artery stenting |
EP2633876B1 (en) | 2012-03-02 | 2014-09-24 | Cook Medical Technologies LLC | Dilation cap for endoluminal device |
WO2014018617A1 (en) | 2012-07-26 | 2014-01-30 | Cook Medical Technologies, LLC | Multi-barrel syringe injection system |
US9033917B2 (en) | 2012-08-15 | 2015-05-19 | Abbott Cardiovascular Systems Inc. | Needle catheter for delivery of agents directly into vessel wall |
US9155862B2 (en) | 2012-09-28 | 2015-10-13 | Covidien Lp | Symmetrical tip acute catheter |
US9286673B2 (en) | 2012-10-05 | 2016-03-15 | Volcano Corporation | Systems for correcting distortions in a medical image and methods of use thereof |
EP2904671B1 (en) | 2012-10-05 | 2022-05-04 | David Welford | Systems and methods for amplifying light |
US9324141B2 (en) | 2012-10-05 | 2016-04-26 | Volcano Corporation | Removal of A-scan streaking artifact |
US9307926B2 (en) | 2012-10-05 | 2016-04-12 | Volcano Corporation | Automatic stent detection |
US10070827B2 (en) | 2012-10-05 | 2018-09-11 | Volcano Corporation | Automatic image playback |
US9367965B2 (en) | 2012-10-05 | 2016-06-14 | Volcano Corporation | Systems and methods for generating images of tissue |
US11272845B2 (en) | 2012-10-05 | 2022-03-15 | Philips Image Guided Therapy Corporation | System and method for instant and automatic border detection |
US9292918B2 (en) | 2012-10-05 | 2016-03-22 | Volcano Corporation | Methods and systems for transforming luminal images |
US9858668B2 (en) | 2012-10-05 | 2018-01-02 | Volcano Corporation | Guidewire artifact removal in images |
US10568586B2 (en) | 2012-10-05 | 2020-02-25 | Volcano Corporation | Systems for indicating parameters in an imaging data set and methods of use |
EP2719420A1 (en) * | 2012-10-12 | 2014-04-16 | Becton Dickinson France | Adaptor for a drug delivery device and method for mounting said adaptor thereon |
US9840734B2 (en) | 2012-10-22 | 2017-12-12 | Raindance Technologies, Inc. | Methods for analyzing DNA |
US9301795B2 (en) | 2012-10-29 | 2016-04-05 | Ablative Solutions, Inc. | Transvascular catheter for extravascular delivery |
US10881458B2 (en) | 2012-10-29 | 2021-01-05 | Ablative Solutions, Inc. | Peri-vascular tissue ablation catheters |
US9554849B2 (en) | 2012-10-29 | 2017-01-31 | Ablative Solutions, Inc. | Transvascular method of treating hypertension |
US10226278B2 (en) | 2012-10-29 | 2019-03-12 | Ablative Solutions, Inc. | Method for painless renal denervation using a peri-vascular tissue ablation catheter with support structures |
US10945787B2 (en) | 2012-10-29 | 2021-03-16 | Ablative Solutions, Inc. | Peri-vascular tissue ablation catheters |
US10736656B2 (en) | 2012-10-29 | 2020-08-11 | Ablative Solutions | Method for painless renal denervation using a peri-vascular tissue ablation catheter with support structures |
US9526827B2 (en) | 2012-10-29 | 2016-12-27 | Ablative Solutions, Inc. | Peri-vascular tissue ablation catheter with support structures |
US10639179B2 (en) * | 2012-11-21 | 2020-05-05 | Ram Medical Innovations, Llc | System for the intravascular placement of a medical device |
EP2931132B1 (en) | 2012-12-13 | 2023-07-05 | Philips Image Guided Therapy Corporation | System for targeted cannulation |
US11406498B2 (en) | 2012-12-20 | 2022-08-09 | Philips Image Guided Therapy Corporation | Implant delivery system and implants |
US9709379B2 (en) | 2012-12-20 | 2017-07-18 | Volcano Corporation | Optical coherence tomography system that is reconfigurable between different imaging modes |
EP2934282B1 (en) | 2012-12-20 | 2020-04-29 | Volcano Corporation | Locating intravascular images |
EP2934311B1 (en) | 2012-12-20 | 2020-04-15 | Volcano Corporation | Smooth transition catheters |
US10942022B2 (en) | 2012-12-20 | 2021-03-09 | Philips Image Guided Therapy Corporation | Manual calibration of imaging system |
US10939826B2 (en) | 2012-12-20 | 2021-03-09 | Philips Image Guided Therapy Corporation | Aspirating and removing biological material |
WO2014099760A1 (en) | 2012-12-21 | 2014-06-26 | Mai Jerome | Ultrasound imaging with variable line density |
US9486143B2 (en) | 2012-12-21 | 2016-11-08 | Volcano Corporation | Intravascular forward imaging device |
WO2014099672A1 (en) | 2012-12-21 | 2014-06-26 | Andrew Hancock | System and method for multipath processing of image signals |
JP2016508757A (ja) | 2012-12-21 | 2016-03-24 | ジェイソン スペンサー, | 医療データのグラフィカル処理のためのシステムおよび方法 |
US9612105B2 (en) | 2012-12-21 | 2017-04-04 | Volcano Corporation | Polarization sensitive optical coherence tomography system |
US10058284B2 (en) | 2012-12-21 | 2018-08-28 | Volcano Corporation | Simultaneous imaging, monitoring, and therapy |
WO2014100530A1 (en) | 2012-12-21 | 2014-06-26 | Whiseant Chester | System and method for catheter steering and operation |
EP2934653B1 (en) | 2012-12-21 | 2018-09-19 | Douglas Meyer | Rotational ultrasound imaging catheter with extended catheter body telescope |
CA2896004A1 (en) | 2012-12-21 | 2014-06-26 | Nathaniel J. Kemp | Power-efficient optical buffering using optical switch |
US9364209B2 (en) | 2012-12-21 | 2016-06-14 | Abbott Cardiovascular Systems, Inc. | Articulating suturing device |
JP2016507892A (ja) | 2012-12-21 | 2016-03-10 | デイビッド ウェルフォード, | 光の波長放出を狭幅化するためのシステムおよび方法 |
WO2014120741A1 (en) | 2013-01-30 | 2014-08-07 | Vascular Pathways, Inc. | Systems and methods for venipuncture and catheter placement |
US10226597B2 (en) | 2013-03-07 | 2019-03-12 | Volcano Corporation | Guidewire with centering mechanism |
JP6243453B2 (ja) | 2013-03-07 | 2017-12-06 | ボルケーノ コーポレイション | 血管内画像におけるマルチモーダルセグメンテーション |
WO2014164696A1 (en) | 2013-03-12 | 2014-10-09 | Collins Donna | Systems and methods for diagnosing coronary microvascular disease |
US11154313B2 (en) | 2013-03-12 | 2021-10-26 | The Volcano Corporation | Vibrating guidewire torquer and methods of use |
US11026591B2 (en) | 2013-03-13 | 2021-06-08 | Philips Image Guided Therapy Corporation | Intravascular pressure sensor calibration |
JP6339170B2 (ja) | 2013-03-13 | 2018-06-06 | ジンヒョン パーク | 回転式血管内超音波装置から画像を生成するためのシステム及び方法 |
US9301687B2 (en) | 2013-03-13 | 2016-04-05 | Volcano Corporation | System and method for OCT depth calibration |
US10292677B2 (en) | 2013-03-14 | 2019-05-21 | Volcano Corporation | Endoluminal filter having enhanced echogenic properties |
US10426590B2 (en) | 2013-03-14 | 2019-10-01 | Volcano Corporation | Filters with echogenic characteristics |
US10219887B2 (en) | 2013-03-14 | 2019-03-05 | Volcano Corporation | Filters with echogenic characteristics |
US20140296789A1 (en) * | 2013-03-27 | 2014-10-02 | Kody El-Mohtar | Multi-Lumen Needle and Catheter Guidance System |
US9931046B2 (en) | 2013-10-25 | 2018-04-03 | Ablative Solutions, Inc. | Intravascular catheter with peri-vascular nerve activity sensors |
US9949652B2 (en) | 2013-10-25 | 2018-04-24 | Ablative Solutions, Inc. | Apparatus for effective ablation and nerve sensing associated with denervation |
US10517666B2 (en) | 2013-10-25 | 2019-12-31 | Ablative Solutions, Inc. | Apparatus for effective ablation and nerve sensing associated with denervation |
US9855402B2 (en) | 2014-02-15 | 2018-01-02 | Rex Medical, L.P. | Apparatus for delivering fluid to treat renal hypertension |
US10065017B2 (en) | 2014-04-02 | 2018-09-04 | Merit Medical Systems, Inc. | Catheter with catheter tip and related methods |
CN106455985B (zh) | 2014-05-16 | 2019-09-17 | 阿莱瓦神经治疗股份有限公司 | 与神经组织相互作用的装置及其制造和使用方法 |
US11311718B2 (en) | 2014-05-16 | 2022-04-26 | Aleva Neurotherapeutics Sa | Device for interacting with neurological tissue and methods of making and using the same |
US9949874B2 (en) * | 2014-06-06 | 2018-04-24 | Janssen Biotech, Inc. | Therapeutic agent delivery device with convergent lumen |
WO2016019160A1 (en) * | 2014-07-30 | 2016-02-04 | University Of Kansas | Cannula for external drainage of subretinal fluid |
US9403011B2 (en) | 2014-08-27 | 2016-08-02 | Aleva Neurotherapeutics | Leadless neurostimulator |
US9474894B2 (en) | 2014-08-27 | 2016-10-25 | Aleva Neurotherapeutics | Deep brain stimulation lead |
WO2016037127A1 (en) | 2014-09-05 | 2016-03-10 | C.R. Bard, Inc. | Catheter insertion device including retractable needle |
US9668725B2 (en) * | 2015-03-24 | 2017-06-06 | Richard B. Beaven | Laparoscopic wound closure device |
US9636244B2 (en) | 2015-04-09 | 2017-05-02 | Mubin I. Syed | Apparatus and method for proximal to distal stent deployment |
USD903100S1 (en) | 2015-05-01 | 2020-11-24 | C. R. Bard, Inc. | Catheter placement device |
ES2910665T3 (es) | 2015-05-15 | 2022-05-13 | Bard Inc C R | Dispositivo de inserción de catéter |
WO2017066262A1 (en) | 2015-10-12 | 2017-04-20 | Swaminathan Jayaraman | System and method for delivery of a therapeutic agent through a catheter |
US10492936B2 (en) | 2015-10-30 | 2019-12-03 | Ram Medical Innovations, Llc | Apparatus and method for improved access of procedural catheter in tortuous vessels |
US10327929B2 (en) | 2015-10-30 | 2019-06-25 | Ram Medical Innovations, Llc | Apparatus and method for stabilization of procedural catheter in tortuous vessels |
US10779976B2 (en) | 2015-10-30 | 2020-09-22 | Ram Medical Innovations, Llc | Apparatus and method for stabilization of procedural catheter in tortuous vessels |
US11020256B2 (en) | 2015-10-30 | 2021-06-01 | Ram Medical Innovations, Inc. | Bifurcated “Y” anchor support for coronary interventions |
US9980838B2 (en) | 2015-10-30 | 2018-05-29 | Ram Medical Innovations Llc | Apparatus and method for a bifurcated catheter for use in hostile aortic arches |
US20170164942A1 (en) * | 2015-12-15 | 2017-06-15 | Heartstitch, Inc. | Holding Block For Multiple Catheter Needles |
WO2017134587A1 (en) | 2016-02-02 | 2017-08-10 | Aleva Neurotherapeutics, Sa | Treatment of autoimmune diseases with deep brain stimulation |
US10173031B2 (en) | 2016-06-20 | 2019-01-08 | Mubin I. Syed | Interchangeable flush/selective catheter |
CA3034478A1 (en) | 2016-09-12 | 2018-03-15 | C.R. Bard, Inc. | Blood control for a catheter insertion device |
GB2555611A (en) * | 2016-11-04 | 2018-05-09 | Gbuk Group Ltd | Improvements to a bolus, an enteral tube and/or a catheter |
JP6953541B2 (ja) | 2017-03-01 | 2021-10-27 | シー・アール・バード・インコーポレーテッドC R Bard Incorporated | カテーテル挿入装置 |
US20180333042A1 (en) * | 2017-05-18 | 2018-11-22 | Loubert S. Suddaby | Self-anchoring endoscopy sheath |
EP3415106B1 (en) | 2017-06-14 | 2022-08-03 | IMEC vzw | Brain interaction apparatus, cranial anchor, and related systems |
RU176144U1 (ru) * | 2017-07-03 | 2018-01-09 | Рашид Саидович Хадиев | Нанокатетер для введения/извлечения межклеточной жидкости из/в биологическую среду |
DE102017126428A1 (de) * | 2017-11-10 | 2019-05-16 | Bavaria Medizin Technologie Gmbh | Katheter zur Injektion und/oder Applikation eines Fluids |
CN107744412A (zh) * | 2017-11-20 | 2018-03-02 | 中国人民解放军第四五五医院 | 局部麻醉药物注射用套筒以及注射组件 |
US11116561B2 (en) | 2018-01-24 | 2021-09-14 | Medtronic Ardian Luxembourg S.A.R.L. | Devices, agents, and associated methods for selective modulation of renal nerves |
US11007075B2 (en) | 2018-02-18 | 2021-05-18 | Ram Medical Innovations, Inc. | Vascular access devices and methods for lower limb interventions |
US10702692B2 (en) | 2018-03-02 | 2020-07-07 | Aleva Neurotherapeutics | Neurostimulation device |
EP3762084B1 (en) | 2018-03-07 | 2024-04-24 | Bard Access Systems, Inc. | Guidewire advancement and blood flashback systems for a medical device insertion system |
CA3101200A1 (en) | 2018-06-18 | 2019-12-26 | Becton Dickinson and Company Limited | Piercing member for vial adapter |
US10849685B2 (en) | 2018-07-18 | 2020-12-01 | Ablative Solutions, Inc. | Peri-vascular tissue access catheter with locking handle |
USD921884S1 (en) | 2018-07-27 | 2021-06-08 | Bard Access Systems, Inc. | Catheter insertion device |
US11154312B2 (en) | 2019-04-05 | 2021-10-26 | Traverse Vascular, Inc. | Reentry catheter for crossing a vascular occlusion |
JP2022545447A (ja) | 2019-08-19 | 2022-10-27 | ベクトン・ディキンソン・アンド・カンパニー | 正中線カテーテル配置デバイス |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3598119A (en) * | 1970-02-02 | 1971-08-10 | Charles A White | Continuous paracervical anesthesia method and device |
US4136695A (en) * | 1975-07-09 | 1979-01-30 | Gynetech-Denver, Inc. | Transvaginal sterilization instrument |
US4578061A (en) * | 1980-10-28 | 1986-03-25 | Lemelson Jerome H | Injection catheter and method |
US5370675A (en) | 1992-08-12 | 1994-12-06 | Vidamed, Inc. | Medical probe device and method |
FR2560052B1 (fr) * | 1984-02-29 | 1988-02-05 | Benhaim Jean | Perfectionnement a une sonde de catheterisme vasculaire |
US4940064A (en) * | 1986-11-14 | 1990-07-10 | Desai Jawahar M | Catheter for mapping and ablation and method therefor |
DE8913761U1 (de) * | 1989-11-21 | 1990-03-29 | GIP Gastrointestinale Produkte Vertriebs GmbH, 8221 Grabenstätt | Endoskopische Fibrinkleber-Injektionsvorrichtung |
ATE124616T1 (de) * | 1990-12-10 | 1995-07-15 | Howmedica | Vorrichtung zur interstitiellen applikation von laserlicht. |
DE4235506A1 (de) * | 1992-10-21 | 1994-04-28 | Bavaria Med Tech | Katheter zur Injektion von Arzneimitteln |
-
1994
- 1994-03-10 DE DE4408108A patent/DE4408108A1/de not_active Withdrawn
- 1994-05-02 US US08/235,900 patent/US5419777A/en not_active Expired - Lifetime
- 1994-08-29 CN CN94195056A patent/CN1143326A/zh active Pending
- 1994-08-29 EP EP94926218A patent/EP0738165B1/de not_active Expired - Lifetime
- 1994-08-29 JP JP52317895A patent/JP3695756B2/ja not_active Expired - Fee Related
- 1994-08-29 ES ES94926218T patent/ES2118431T3/es not_active Expired - Lifetime
- 1994-08-29 RU RU96120144A patent/RU2139105C1/ru not_active IP Right Cessation
- 1994-08-29 DE DE59405922T patent/DE59405922D1/de not_active Expired - Lifetime
- 1994-08-29 HU HU9602222A patent/HU219512B/hu not_active IP Right Cessation
- 1994-08-29 CA CA002184388A patent/CA2184388C/en not_active Expired - Lifetime
- 1994-08-29 PL PL94316201A patent/PL176254B1/pl unknown
- 1994-08-29 BR BR9408549A patent/BR9408549A/pt not_active IP Right Cessation
- 1994-08-29 CZ CZ962553A patent/CZ255396A3/cs unknown
- 1994-08-29 SK SK1157-96A patent/SK115796A3/sk unknown
- 1994-08-29 SI SI9420081A patent/SI9420081A/sl unknown
- 1994-08-29 DK DK94926218T patent/DK0738165T3/da active
- 1994-08-29 AT AT94926218T patent/ATE165740T1/de not_active IP Right Cessation
- 1994-08-29 AU AU76144/94A patent/AU684542B2/en not_active Ceased
- 1994-08-29 WO PCT/EP1994/002850 patent/WO1995024235A1/de not_active Application Discontinuation
- 1994-08-29 UA UA96103865A patent/UA28048C2/uk unknown
- 1994-08-29 SG SG1996005990A patent/SG46563A1/en unknown
- 1994-10-15 MY MYPI94002750A patent/MY113972A/en unknown
- 1994-12-10 PH PH49168A patent/PH31501A/en unknown
-
1996
- 1996-08-22 KR KR1019960704610A patent/KR0181591B1/ko not_active Application Discontinuation
- 1996-09-03 NO NO19963659A patent/NO313578B1/no unknown
- 1996-09-04 FI FI963458A patent/FI963458A/fi unknown
- 1996-09-05 BG BG100828A patent/BG100828A/bg unknown
- 1996-09-24 LV LVP-96-382A patent/LV11733B/lv unknown
-
1998
- 1998-08-05 GR GR980401769T patent/GR3027583T3/el unknown
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