CN114306128A - Anti-aging and anti-firming composition and preparation method thereof - Google Patents
Anti-aging and anti-firming composition and preparation method thereof Download PDFInfo
- Publication number
- CN114306128A CN114306128A CN202111667281.2A CN202111667281A CN114306128A CN 114306128 A CN114306128 A CN 114306128A CN 202111667281 A CN202111667281 A CN 202111667281A CN 114306128 A CN114306128 A CN 114306128A
- Authority
- CN
- China
- Prior art keywords
- aging
- water
- peptide
- extract
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 29
- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 49
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 49
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 36
- 239000000126 substance Substances 0.000 claims abstract description 36
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 35
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 33
- 150000001875 compounds Chemical class 0.000 claims abstract description 19
- 239000008213 purified water Substances 0.000 claims abstract description 15
- 239000003906 humectant Substances 0.000 claims abstract description 13
- 239000003755 preservative agent Substances 0.000 claims abstract description 13
- 239000002562 thickening agent Substances 0.000 claims abstract description 13
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 12
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 11
- 230000002335 preservative effect Effects 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 65
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 54
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 25
- 235000011187 glycerol Nutrition 0.000 claims description 25
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 25
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 25
- 238000013329 compounding Methods 0.000 claims description 24
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 21
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 21
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 18
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 18
- 239000002131 composite material Substances 0.000 claims description 16
- 229920001577 copolymer Polymers 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 15
- 241001530056 Athelia rolfsii Species 0.000 claims description 13
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 12
- 238000004945 emulsification Methods 0.000 claims description 12
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims description 11
- 229920001285 xanthan gum Polymers 0.000 claims description 11
- 239000000230 xanthan gum Substances 0.000 claims description 11
- 235000010493 xanthan gum Nutrition 0.000 claims description 11
- 229940082509 xanthan gum Drugs 0.000 claims description 11
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 claims description 10
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 claims description 10
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims description 10
- 229920002126 Acrylic acid copolymer Polymers 0.000 claims description 9
- NTMADBCZHNCQCJ-UHFFFAOYSA-N [SiH3]O.N1(C)C(=O)N(C)C=2N=CN(C)C2C1=O Chemical compound [SiH3]O.N1(C)C(=O)N(C)C=2N=CN(C)C2C1=O NTMADBCZHNCQCJ-UHFFFAOYSA-N 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 9
- 108050003126 conotoxin Proteins 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 9
- 229940087068 glyceryl caprylate Drugs 0.000 claims description 9
- 229920001542 oligosaccharide Polymers 0.000 claims description 9
- 150000002482 oligosaccharides Chemical class 0.000 claims description 9
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 9
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical compound CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 claims description 9
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims description 8
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims description 8
- 229960000367 inositol Drugs 0.000 claims description 8
- 229930000184 phytotoxin Natural products 0.000 claims description 8
- 239000003123 plant toxin Substances 0.000 claims description 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 8
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims description 8
- OGNHOGPWQTWKGQ-VGWMRTNUSA-N (2S)-5-amino-2-[[(2S)-1-[2-[[(2S)-5-amino-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid Chemical compound NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N1[C@H](C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 OGNHOGPWQTWKGQ-VGWMRTNUSA-N 0.000 claims description 7
- WSGCRSMLXFHGRM-DEVHWETNSA-N (2s)-2-[[(2s)-6-amino-2-[[(2s,3r)-2-[[(2s,3r)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O WSGCRSMLXFHGRM-DEVHWETNSA-N 0.000 claims description 7
- VFKZECOCJCGZQK-UHFFFAOYSA-M 3-hydroxypropyl(trimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCO VFKZECOCJCGZQK-UHFFFAOYSA-M 0.000 claims description 7
- BYUQATUKPXLFLZ-UIOOFZCWSA-N CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(O)=O)CC1=CN=CN1 Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(O)=O)CC1=CN=CN1 BYUQATUKPXLFLZ-UIOOFZCWSA-N 0.000 claims description 7
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 7
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 7
- 229910052802 copper Inorganic materials 0.000 claims description 7
- 239000010949 copper Substances 0.000 claims description 7
- 229920006037 cross link polymer Polymers 0.000 claims description 7
- 229940093441 palmitoyl oligopeptide Drugs 0.000 claims description 7
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims description 6
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 6
- 239000004475 Arginine Substances 0.000 claims description 6
- YDSVPIYLRFZLAT-UHFFFAOYSA-N C(C)(=O)O.C(C)(=O)O.NC(CCC(=O)NCC1=CC=CC=C1)N Chemical compound C(C)(=O)O.C(C)(=O)O.NC(CCC(=O)NCC1=CC=CC=C1)N YDSVPIYLRFZLAT-UHFFFAOYSA-N 0.000 claims description 6
- 102000008186 Collagen Human genes 0.000 claims description 6
- 108010035532 Collagen Proteins 0.000 claims description 6
- 108010016626 Dipeptides Proteins 0.000 claims description 6
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 6
- 239000004472 Lysine Substances 0.000 claims description 6
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 6
- 241000270295 Serpentes Species 0.000 claims description 6
- 229960000458 allantoin Drugs 0.000 claims description 6
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 6
- 235000019437 butane-1,3-diol Nutrition 0.000 claims description 6
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 6
- 235000010418 carrageenan Nutrition 0.000 claims description 6
- 229940074992 chondrus crispus extract Drugs 0.000 claims description 6
- 229920001436 collagen Polymers 0.000 claims description 6
- -1 glyceryl acrylate Chemical compound 0.000 claims description 6
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 claims description 6
- 229920000058 polyacrylate Polymers 0.000 claims description 6
- 229920001184 polypeptide Polymers 0.000 claims description 6
- 229940078492 ppg-17 Drugs 0.000 claims description 6
- 230000032683 aging Effects 0.000 claims description 5
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 230000003301 hydrolyzing effect Effects 0.000 claims description 4
- 150000007524 organic acids Chemical class 0.000 claims description 4
- FCGXLCNBWYIEAA-UHFFFAOYSA-N 1,3-benzothiazol-6-ylmethanamine Chemical compound NCC1=CC=C2N=CSC2=C1 FCGXLCNBWYIEAA-UHFFFAOYSA-N 0.000 claims description 3
- 229940058015 1,3-butylene glycol Drugs 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 claims description 3
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 claims description 3
- 240000004507 Abelmoschus esculentus Species 0.000 claims description 3
- 235000003934 Abelmoschus esculentus Nutrition 0.000 claims description 3
- 241000543324 Adinandra Species 0.000 claims description 3
- 241000045403 Astragalus propinquus Species 0.000 claims description 3
- OBMZMSLWNNWEJA-XNCRXQDQSA-N C1=CC=2C(C[C@@H]3NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CCN(CCCC[C@H](NC(=O)[C@@H](CC4=CC=CC=C4)NC3=O)C(=O)N)CC=C)NC(=O)[C@@H](N)C)CC3=CNC4=C3C=CC=C4)C)=CNC=2C=C1 Chemical compound C1=CC=2C(C[C@@H]3NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CCN(CCCC[C@H](NC(=O)[C@@H](CC4=CC=CC=C4)NC3=O)C(=O)N)CC=C)NC(=O)[C@@H](N)C)CC3=CNC4=C3C=CC=C4)C)=CNC=2C=C1 OBMZMSLWNNWEJA-XNCRXQDQSA-N 0.000 claims description 3
- 241000206575 Chondrus crispus Species 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 3
- 241000195619 Euglena gracilis Species 0.000 claims description 3
- 240000008917 Glycyrrhiza uralensis Species 0.000 claims description 3
- 235000000554 Glycyrrhiza uralensis Nutrition 0.000 claims description 3
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims description 3
- SAVLIIGUQOSOEP-UHFFFAOYSA-N N-octanoylglycine Chemical compound CCCCCCCC(=O)NCC(O)=O SAVLIIGUQOSOEP-UHFFFAOYSA-N 0.000 claims description 3
- 101710176384 Peptide 1 Proteins 0.000 claims description 3
- 241001180873 Saposhnikovia divaricata Species 0.000 claims description 3
- 240000004534 Scutellaria baicalensis Species 0.000 claims description 3
- 235000017089 Scutellaria baicalensis Nutrition 0.000 claims description 3
- LZDNBBYBDGBADK-KBPBESRZSA-N Val-Trp Chemical compound C1=CC=C2C(C[C@H](NC(=O)[C@@H](N)C(C)C)C(O)=O)=CNC2=C1 LZDNBBYBDGBADK-KBPBESRZSA-N 0.000 claims description 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 3
- 230000003266 anti-allergic effect Effects 0.000 claims description 3
- 239000000043 antiallergic agent Substances 0.000 claims description 3
- 235000006533 astragalus Nutrition 0.000 claims description 3
- 229940104591 atractylodes macrocephala root extract Drugs 0.000 claims description 3
- 229960001948 caffeine Drugs 0.000 claims description 3
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims description 3
- 229940059958 centella asiatica extract Drugs 0.000 claims description 3
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 3
- POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 claims description 3
- 229940100524 ethylhexylglycerin Drugs 0.000 claims description 3
- 150000004676 glycans Chemical class 0.000 claims description 3
- 229960005150 glycerol Drugs 0.000 claims description 3
- 229940119204 hibiscus sabdariffa flower extract Drugs 0.000 claims description 3
- 238000000265 homogenisation Methods 0.000 claims description 3
- 229940070765 laurate Drugs 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- ZJBHFQKJEBGFNL-UHFFFAOYSA-N methylsilanetriol Chemical compound C[Si](O)(O)O ZJBHFQKJEBGFNL-UHFFFAOYSA-N 0.000 claims description 3
- RGUVUPQQFXCJFC-UHFFFAOYSA-N n-hydroxyoctanamide Chemical compound CCCCCCCC(=O)NO RGUVUPQQFXCJFC-UHFFFAOYSA-N 0.000 claims description 3
- 235000005985 organic acids Nutrition 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 229920001282 polysaccharide Polymers 0.000 claims description 3
- 239000005017 polysaccharide Substances 0.000 claims description 3
- 229940089952 silanetriol Drugs 0.000 claims description 3
- 239000003998 snake venom Substances 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 230000003750 conditioning effect Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 235000006708 antioxidants Nutrition 0.000 claims 3
- 239000004599 antimicrobial Substances 0.000 claims 1
- 210000003491 skin Anatomy 0.000 abstract description 31
- 230000000694 effects Effects 0.000 abstract description 13
- 230000037303 wrinkles Effects 0.000 abstract description 9
- 230000003020 moisturizing effect Effects 0.000 abstract description 5
- 206010050637 Skin tightness Diseases 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 235000015097 nutrients Nutrition 0.000 abstract description 3
- 210000004927 skin cell Anatomy 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 239000002537 cosmetic Substances 0.000 abstract description 2
- 230000001502 supplementing effect Effects 0.000 abstract description 2
- 239000006071 cream Substances 0.000 abstract 2
- 239000000047 product Substances 0.000 description 14
- 230000006870 function Effects 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- 244000089742 Citrus aurantifolia Species 0.000 description 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 2
- 235000011941 Tilia x europaea Nutrition 0.000 description 2
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 239000004571 lime Substances 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 230000008719 thickening Effects 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000036560 skin regeneration Effects 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 230000037314 wound repair Effects 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention provides an anti-aging and anti-firming composition and a preparation method thereof, which relate to the technical field of cosmetics and comprise the following raw materials in percentage by weight: 0.2-0.5% of thickening agent, 10-20% of humectant, 0.2-0.3% of antioxidant, 0.5-1% of preservative, 1-5% of multiple compound peptide, 0.6-1% of skin conditioner, 1-2% of multiple hyaluronic acid and the balance of purified water. The skin moisturizing cream has the beneficial effects that the skin moisturizing cream can effectively reduce wrinkles, rebuild skin tightness and enable the skin to be smoother and firmer by moisturizing the skin and supplementing moisture content and other nutrient substances, is combined with long-acting effect in time, has good absorption effect, enables skin cells to be sufficiently moisturized and elastic, and is simple in preparation method, short in production period, simple in prescription and relatively reasonable in cost.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to an anti-aging and anti-firming composition and a preparation method thereof.
Background
Skin aging is a normal phenomenon that occurs all the time from birth of a human, and as a result, in addition to the physiological function of the skin, most importantly, the appearance of the human is changed. In the modern society, along with the improvement of the living standard of people, people pay more and more attention to the quality of life, love beauty, and are all people, people are eager to keep young, and the full and young face appearance increases the self-confidence and the enthusiasm of people in life, so the face appearance is long-standing and is pursued by more and more people. The increase of wrinkles affects the appearance of people, especially women, and has higher demand for anti-aging and firming skin care products.
Because the wrinkles are generated by internal and external factors gradually over a period of time, the difficulty of removing the wrinkles is high, the products which claim to have the anti-aging and anti-firming effects on the market at present have not ideal effects actually, and a few products which really have the anti-aging and anti-firming effects.
Disclosure of Invention
The invention overcomes the defects in the prior art, provides the anti-aging and firming composition, can moisturize the skin, supplement water content and other nutrient substances, can effectively reduce wrinkles, reestablish the skin tightness, ensure that the skin is better smooth and firmed, is combined with long action in time, has good absorption effect, ensures that skin cells are sufficiently moisturized and has sufficient elasticity, and the preparation method is simple, the production period is short, the prescription is simple, the cost is relatively reasonable
In order to solve the technical problems, the invention is realized by the following technical scheme:
the anti-aging and anti-firming composition comprises the following raw materials in percentage by weight: 0.2-0.5% of thickening agent, 10-20% of humectant, 0.2-0.3% of antioxidant, 0.5-1% of preservative, 1-5% of multiple compound peptide, 0.6-1% of skin conditioner, 1-2% of multiple hyaluronic acid and the balance of purified water.
Further, the thickener is 0.23%, the humectant is 10.5%, the antioxidant is 0.22%, the preservative is 0.7%, the multiple composite peptide is 1.6%, the skin conditioner is 5.7%, the multiple hyaluronic acid is 1%, and the balance is purified water.
Still further, the thickener comprises the following: hydrolyzed sclerotium rolfsii gum and xanthan gum.
Still further, the moisturizer comprises the following: 1, 3-butylene glycol, water/glycerol/glyceryl acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer, Chondrus crispus extract/algal oligosaccharides/1, 2-pentanediol, glyceryl polyether-26.
Still further, the antioxidant comprises the following: p-hydroxyacetophenone.
Still further, the preservative includes the following: the organic acids caprylhydroxamic acid/glyceryl caprylate/propylene glycol or caprylylglycine.
Still further, the multiple composite peptide comprises the following: dipeptide diaminobutyrylbenzylamide diacetate, arginine/lysine polypeptide, acetyl hexapeptide-8, palmitoyl tripeptide-1/palmitoyl pentapeptide-4/hexapeptide-9/tripeptide-1 copper.
Still further, the multiplex hyaluronic acid comprises the following substances: hyaluronic acid, sodium hyaluronate cross-linked polymer, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans and hydroxypropyl trimethyl ammonium chloride hyaluronic acid.
The preparation method of the anti-aging and anti-firming composition comprises the following specific steps:
(1) weighing the following components in percentage by weight: hydrolyzed sclerotium rolfsii gum 0.18%, xanthan gum 0.05%, 1, 3-butanediol 6%, water/glycerin/glyceryl acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer 2%, glyceryl polyether-262%, PEG/PPG-17/6 copolymer 1%, Chondrus crispus extract/algal oligosaccharide/1%, 2-pentanediol 0.5%, allantoin 0.2%, disodium EDTA 0.02%, p-hydroxyacetophenone 0.2%, 1, 2-hexanediol 0.3%, propylene glycol/caprylyl hydroximic acid/glyceryl caprylate 0.4%, herbal composite anti-sensitivity agent 0.35%, inositol 3%, acetyl hexapeptide-80.5%, multiple composite peptide 1%, MP-90M 2%, caffeine silanol C0.6%, snake venom like peptide 0.1%, conotoxin peptide 0.001%, phytotoxin 0.1%, 1% of hyaluronic acid with seven weight portions and the balance of purified water;
(2) dispersing hydrolyzed sclerotium rolfsii gum and xanthan gum in butanediol, firstly putting the materials into an emulsification tank for homogenization for 2 minutes, then adding allantoin, EDTA disodium, water/glycerol/glycerinacrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer and purified water into the emulsification tank, heating to 80-90 ℃ under stirring, continuing to preserve heat and stir for 30 minutes, and then cooling to 45 ℃;
(3) heating p-hydroxyacetophenone and 1, 2-hexanediol in a proper container to dissolve and transparent, cooling to normal temperature, adding propylene glycol/caprylyl hydroximic acid/glyceryl caprylate and stirring uniformly, and then putting the mixture into an emulsification tank to stir uniformly;
(4) and (2) adding glycerol polyether-26, PEG/PPG-17/6 copolymer, the composite herbal anti-allergy liquid, carrageen crispus extract/algal oligosaccharides/1, 2-pentanediol, inositol, heptahyaluronic acid, acetyl hexapeptide-8, the multiple composite peptide, MP-90M, phytotoxin, caffeine silanol C, snake venom-like peptide and conotoxin peptide into an emulsification tank successively, stirring uniformly, and cooling to 35-45 ℃ to obtain the composition for resisting aging and immediately combining with long-acting tightening.
Furthermore, the herbal compound anti-allergy agent is prepared by compounding the following substances: water, Astragalus membranaceus extract, Scutellaria baicalensis root extract, Atractylodes macrocephala root extract, Saposhnikovia divaricata root extract, Abelmoschus esculentus extract, Glycyrrhiza uralensis extract, centella asiatica extract, 1, 2-hexanediol, and ethylhexylglycerin;
the multiple compound peptide is prepared by compounding the following substances: water, butylene glycol, glycerol, 1, 2-hexanediol, polyglycerol-10 laurate, palmitoyl tripeptide-1, palmitoyl pentapeptide-4, hexapeptide-9, acetyl hexapeptide-8, tripeptide-1, and tripeptide-1 copper; the MP-90M is prepared by compounding the following substances: hydrolyzing collagen, euglena gracilis polysaccharide and dipeptide-2;
the caffeine silanol C is prepared by compounding the following substances: water, butylene glycol, caffeine, glycerin, 1, 2-hexanediol, and silanetriol;
the snake venom-like peptide is prepared by compounding the following substances: water, glycerol, 1, 2-hexanediol, ethylhexylglycerol, and dipeptide diaminobutyrylbenzylamide diacetate;
the conotoxin peptide is prepared by compounding the following substances: water, isosorbide dimethyl ether, 1, 2-pentanediol, ethylhexyl glycerol, and arginine/lysine polypeptide;
the phytotoxin is prepared by compounding the following substances: water, glycerin, Adinandra extract and Hibiscus sabdariffa flower extract;
the seven-fold hyaluronic acid is prepared by compounding the following substances: water, sodium hyaluronate crosspolymer, sodium hyaluronate, 1, 2-hexanediol, phenoxyethanol, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans, hyaluronic acid, and hydroxypropyl trimethylammonium chloride hyaluronic acid.
Compared with the prior art, the invention has the beneficial effects that:
the anti-aging and anti-firming composition can effectively reduce wrinkles, rebuild skin tightness and enable skin to be smooth and firmed by moisturizing the skin, supplementing moisture content and other nutrient substances, and is combined with long-acting effect in time, good in absorption effect, sufficient in skin cell moisture and sufficient in elasticity. The preparation method is simple, the production period is short, the prescription is simple, and the cost is relatively reasonable.
Detailed Description
The anti-aging and anti-firming composition comprises the following raw materials in percentage by weight: 0.2-0.5% of thickening agent, 10-20% of humectant, 0.2-0.3% of antioxidant, 0.5-1% of preservative, 1-5% of multiple compound peptide, 0.6-1% of skin conditioner, 1-2% of multiple hyaluronic acid and the balance of purified water.
Example 1
The anti-aging and anti-firming composition comprises the following raw materials in percentage by weight: 0.23% of thickening agent, 10.5% of humectant, 0.22% of antioxidant, 0.7% of preservative, 1.6% of multiple compound peptide, 5.7% of skin conditioner, 1% of multiple hyaluronic acid and the balance of purified water.
Example 2
The anti-aging and anti-firming composition comprises the following raw materials in percentage by weight: 0.5% of thickening agent, 20% of humectant, 0.3% of antioxidant, 1% of preservative, 5% of multiple compound peptide, 1% of skin conditioner, 2% of multiple hyaluronic acid and the balance of purified water.
Example 3
The anti-aging and anti-firming composition comprises the following raw materials in percentage by weight: 0.2% of thickening agent, 10% of humectant, 0.2% of antioxidant, 0.5% of preservative, 1% of multiple compound peptide, 0.6% of skin conditioner, 1% of multiple hyaluronic acid and the balance of purified water.
The thickener comprises the following substances: hydrolyzed sclerotium rolfsii gum and xanthan gum.
The humectant comprises the following substances: 1, 3-butylene glycol, water/glycerol/glyceryl acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer, Chondrus crispus extract/algal oligosaccharides/1, 2-pentanediol, glyceryl polyether-26.
Antioxidants include the following: p-hydroxyacetophenone.
Preservatives include the following: the organic acids caprylhydroxamic acid/glyceryl caprylate/propylene glycol or caprylylglycine.
The multiple composite peptide comprises the following substances: dipeptide diaminobutyrylbenzylamide diacetate, arginine/lysine polypeptide, acetyl hexapeptide-8, palmitoyl tripeptide-1/palmitoyl pentapeptide-4/hexapeptide-9/tripeptide-1 copper.
The multiple hyaluronic acid comprises the following substances: hyaluronic acid, sodium hyaluronate cross-linked polymer, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans and hydroxypropyl trimethyl ammonium chloride hyaluronic acid.
The preparation method of the anti-aging and anti-firming composition comprises the following specific steps:
(1) weighing the following components in percentage by weight: hydrolyzed sclerotium rolfsii gum 0.18%, xanthan gum 0.05%, 1, 3-butanediol 6%, water/glycerin/glyceryl acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer 2%, glyceryl polyether-262%, PEG/PPG-17/6 copolymer 1%, Chondrus crispus extract/algal oligosaccharide/1%, 2-pentanediol 0.5%, allantoin 0.2%, disodium EDTA 0.02%, p-hydroxyacetophenone 0.2%, 1, 2-hexanediol 0.3%, propylene glycol/caprylyl hydroximic acid/glyceryl caprylate 0.4%, herbal composite anti-sensitivity agent 0.35%, inositol 3%, acetyl hexapeptide-80.5%, multiple composite peptide 1%, MP-90M 2%, caffeine silanol C0.6%, snake venom like peptide 0.1%, conotoxin peptide 0.001%, phytotoxin 0.1%, 1% of hyaluronic acid with seven weight portions and the balance of purified water;
(2) dispersing hydrolyzed sclerotium rolfsii gum and xanthan gum in butanediol, firstly putting the materials into an emulsification tank for homogenization for 2 minutes, then adding allantoin, EDTA disodium, water/glycerol/glycerinacrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer and purified water into the emulsification tank, heating to 80-90 ℃ under stirring, continuing to preserve heat and stir for 30 minutes, and then cooling to 45 ℃;
(3) heating p-hydroxyacetophenone and 1, 2-hexanediol in a proper container to dissolve and transparent, cooling to normal temperature, adding propylene glycol/caprylyl hydroximic acid/glyceryl caprylate and stirring uniformly, and then putting the mixture into an emulsification tank to stir uniformly;
(4) and (2) adding glycerol polyether-26, PEG/PPG-17/6 copolymer, the composite herbal anti-allergy liquid, carrageen crispus extract/algal oligosaccharides/1, 2-pentanediol, inositol, heptahyaluronic acid, acetyl hexapeptide-8, the multiple composite peptide, MP-90M, phytotoxin, caffeine silanol C, snake venom-like peptide and conotoxin peptide into an emulsification tank successively, stirring uniformly, and cooling to 35-45 ℃ to obtain the composition for resisting aging and immediately combining with long-acting tightening.
The herbal compound anti-allergy agent is prepared by compounding the following substances: water, Astragalus membranaceus extract, Scutellaria baicalensis root extract, Atractylodes macrocephala root extract, Saposhnikovia divaricata root extract, Abelmoschus esculentus extract, Glycyrrhiza uralensis extract, centella asiatica extract, 1, 2-hexanediol, and ethylhexylglycerin;
the multiple compound peptide is prepared by compounding the following substances: water, butylene glycol, glycerol, 1, 2-hexanediol, polyglycerol-10 laurate, palmitoyl tripeptide-1, palmitoyl pentapeptide-4, hexapeptide-9, acetyl hexapeptide-8, tripeptide-1, and tripeptide-1 copper; the MP-90M is prepared by compounding the following substances: hydrolyzing collagen, euglena gracilis polysaccharide and dipeptide-2;
the caffeine silanol C is prepared by compounding the following substances: water, butylene glycol, caffeine, glycerin, 1, 2-hexanediol, and silanetriol;
the snake venom-like peptide is prepared by compounding the following substances: water, glycerol, 1, 2-hexanediol, ethylhexylglycerol, and dipeptide diaminobutyrylbenzylamide diacetate;
the conotoxin peptide is prepared by compounding the following substances: water, isosorbide dimethyl ether, 1, 2-pentanediol, ethylhexyl glycerol, and arginine/lysine polypeptide;
the phytobotulinum toxin is prepared by compounding the following substances: water, glycerin, Adinandra extract and Hibiscus sabdariffa flower extract;
the seven-weight hyaluronic acid is prepared by compounding the following substances: water, sodium hyaluronate crosspolymer, sodium hyaluronate, 1, 2-hexanediol, phenoxyethanol, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans, hyaluronic acid, and hydroxypropyl trimethylammonium chloride hyaluronic acid.
Because the market of the raw materials is complicated, the product is full of limes and limes, the raw materials are updated in an iterative way and are extremely rapid, the raw materials directly determine the product attributes, therefore, the raw materials are carefully selected, the product formula and the process are optimized, and finally the anti-aging instant and long-acting compact combination is formed.
1. The thickening system selects hydrolytic sclerotium rolfsii gum and xanthan gum. The hydrolyzed sclerotium rolfsii gum is not single thickening, and the skin care effect is quite obvious. The hydrolyzed sclerotium rolfsii gum is called sclerotium rolfsii, is a pure natural biological polymer humectant, has stable properties and good water solubility, and can achieve the effect of long-acting moisture retention. Meanwhile, the coating has the functions of repairing, anti-inflammation, antioxidation and the like. The xanthan gum contains a large amount of hydrophilic groups, is a good surface active substance, and has the effects of resisting oxidation, preventing skin aging and the like. Therefore, the two thickening agents are matched to increase the viscosity of the product and bring considerable anti-oxidation, anti-aging and anti-tightening effects.
2. The humectant is selected from butanediol and glycerin polyether, so that the product has a refreshing texture.
3. The preservative is basically an additive-free system, and the preservative is declared to be free by adopting the matching of the polyhydric alcohol and the organic acid, so that the product has the moderate property and safety, and has unique advantages compared with other products on the market.
4. One of the selected functional substances, namely inositol, is called as inositol, has better moisturizing and conditioning functions on the skin, increases the glossiness of the skin, has obvious anti-aging effect on the skin, can promote the synthesis of hyaluronic acid and collagen, ensures that the skin is moist and full, and is a perfect beauty and maintenance holy product. This makes our product comparable to many large cards on the market. The main components of the selected two-seven-hyaluronic acid are hyaluronic acid, sodium hyaluronate, a sodium hyaluronate cross-linked polymer, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans and hydroxypropyl trimethyl ammonium chloride hyaluronic acid, and the two-seven-hyaluronic acid is composed of a three-dimensional matrix of seven hyaluronic acids and derivatives thereof, has the functions of layering and precision, replenishing water, locking water and resisting aging, is released by time-sharing permeation, penetrates into the muscle bottom, develops the skin motive power and resists time-light erosion. The selected three-multiple compound peptide contains six peptides, the three-multiple compound peptide can promote skin regeneration and repair according to the efficacy, the three-multiple compound peptide comprises hexapeptide-9, tripeptide-1 and tripeptide-1 copper, the three-multiple compound peptide can lighten, blur and improve wrinkles and comprises acetyl hexapeptide-8, palmitoyl tripeptide-1 and palmitoyl pentapeptide-4, each peptide plays a unique role, and the three-multiple compound peptide can be used for perfectly caring skin and effectively lightening and blurring existing fine lines/wrinkles in a synergistic manner, preventing wrinkles from generating, improving the integral appearance of the skin, repairing daily skin tissue damage, enabling the skin to recover young and active, maintaining a stable barrier and maintaining the skin to be full and elastic. The product is derived from deep-sea fish, the content of collagen is much higher than that of common fish, the collagen is extracted by a special professional hydrolysis technology, the product is a new generation of environment-friendly skin care active ingredient, a fine film can be formed on the skin, the skin tightening effect is achieved immediately, the fibroblast growth can be activated and promoted, the cell aging is delayed, the fine lines are improved, the cell division proliferation, the cell differentiation, the wound repair and healing are promoted, the skin inflammation is inhibited, and the like.
Finally, it should be noted that: although the present invention has been described in detail with reference to the embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (10)
1. The anti-aging and anti-firming composition is characterized by comprising the following raw materials in percentage by weight: 0.2-0.5% of thickening agent, 10-20% of humectant, 0.2-0.3% of antioxidant, 0.5-1% of preservative, 1-5% of multiple compound peptide, 0.6-1% of skin conditioner, 1-2% of multiple hyaluronic acid and the balance of purified water.
2. The composition for resisting aging and firming as claimed in claim 1, wherein the thickening agent is 0.23%, the humectant is 10.5%, the antioxidant is 0.22%, the antiseptic agent is 0.7%, the multiple compound peptide is 1.6%, the skin conditioning agent is 5.7%, the multiple hyaluronic acid is 1%, and the balance is purified water.
3. The anti-aging and anti-firming composition as claimed in claim 1 or 2, wherein said thickening agent comprises the following: hydrolyzed sclerotium rolfsii gum and xanthan gum.
4. The anti-aging and anti-firming composition as claimed in claim 1 or 2, wherein said humectant comprises: 1, 3-butylene glycol, water/glycerol/glyceryl acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer, Chondrus crispus extract/algal oligosaccharides/1, 2-pentanediol, glyceryl polyether-26.
5. The anti-aging and anti-firming composition as claimed in claim 1 or 2, wherein said anti-oxidant comprises the following: p-hydroxyacetophenone.
6. The anti-aging and anti-firming composition as claimed in claim 1 or 2, wherein said preservatives comprise the following substances: the organic acids caprylhydroxamic acid/glyceryl caprylate/propylene glycol or caprylylglycine.
7. The anti-aging and anti-firming composition according to claim 1 or 2, wherein said multiple composite peptides comprise the following substances: dipeptide diaminobutyrylbenzylamide diacetate, arginine/lysine polypeptide, acetyl hexapeptide-8, palmitoyl tripeptide-1/palmitoyl pentapeptide-4/hexapeptide-9/tripeptide-1 copper.
8. The anti-aging and anti-firming composition according to claim 1 or 2, wherein said hyaluronic acid comprises the following substances: hyaluronic acid, sodium hyaluronate cross-linked polymer, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans and hydroxypropyl trimethyl ammonium chloride hyaluronic acid.
9. The preparation method of the anti-aging and anti-firming composition is characterized by comprising the following specific steps:
(1) weighing the following components in percentage by weight: hydrolyzed sclerotium rolfsii gum 0.18%, xanthan gum 0.05%, 1, 3-butanediol 6%, water/glycerin/glyceryl acrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer 2%, glyceryl polyether-262%, PEG/PPG-17/6 copolymer 1%, Chondrus crispus extract/algal oligosaccharide/1%, 2-pentanediol 0.5%, allantoin 0.2%, disodium EDTA 0.02%, p-hydroxyacetophenone 0.2%, 1, 2-hexanediol 0.3%, propylene glycol/caprylyl hydroximic acid/glyceryl caprylate 0.4%, herbal composite anti-sensitivity agent 0.35%, inositol 3%, acetyl hexapeptide-80.5%, multiple composite peptide 1%, MP-90M 2%, caffeine silanol C0.6%, snake venom like peptide 0.1%, conotoxin peptide 0.001%, phytotoxin 0.1%, 1% of hyaluronic acid with seven weight portions and the balance of purified water;
(2) dispersing hydrolyzed sclerotium rolfsii gum and xanthan gum in butanediol, firstly putting the materials into an emulsification tank for homogenization for 2 minutes, then adding allantoin, EDTA disodium, water/glycerol/glycerinacrylate/acrylic acid copolymer/propylene glycol/PVM/MA copolymer and purified water into the emulsification tank, heating to 80-90 ℃ under stirring, continuing to preserve heat and stir for 30 minutes, and then cooling to 45 ℃;
(3) heating p-hydroxyacetophenone and 1, 2-hexanediol in a proper container to dissolve and transparent, cooling to normal temperature, adding propylene glycol/caprylyl hydroximic acid/glyceryl caprylate and stirring uniformly, and then putting the mixture into an emulsification tank to stir uniformly;
(4) and (2) adding glycerol polyether-26, PEG/PPG-17/6 copolymer, the composite herbal anti-allergy liquid, carrageen crispus extract/algal oligosaccharides/1, 2-pentanediol, inositol, heptahyaluronic acid, acetyl hexapeptide-8, the multiple composite peptide, MP-90M, phytotoxin, caffeine silanol C, snake venom-like peptide and conotoxin peptide into an emulsification tank successively, stirring uniformly, and cooling to 35-45 ℃ to obtain the composition for resisting aging and immediately combining with long-acting tightening.
10. The method for preparing the anti-aging and anti-firming composition according to claim 9,
the herbal compound anti-allergy agent is prepared by compounding the following substances: water, Astragalus membranaceus extract, Scutellaria baicalensis root extract, Atractylodes macrocephala root extract, Saposhnikovia divaricata root extract, Abelmoschus esculentus extract, Glycyrrhiza uralensis extract, centella asiatica extract, 1, 2-hexanediol, and ethylhexylglycerin;
the multiple compound peptide is prepared by compounding the following substances: water, butylene glycol, glycerol, 1, 2-hexanediol, polyglycerol-10 laurate, palmitoyl tripeptide-1, palmitoyl pentapeptide-4, hexapeptide-9, acetyl hexapeptide-8, tripeptide-1, and tripeptide-1 copper;
the MP-90M is prepared by compounding the following substances: hydrolyzing collagen, euglena gracilis polysaccharide and dipeptide-2;
the caffeine silanol C is prepared by compounding the following substances: water, butylene glycol, caffeine, glycerin, 1, 2-hexanediol, and silanetriol;
the snake venom-like peptide is prepared by compounding the following substances: water, glycerol, 1, 2-hexanediol, ethylhexylglycerol, and dipeptide diaminobutyrylbenzylamide diacetate;
the conotoxin peptide is prepared by compounding the following substances: water, isosorbide dimethyl ether, 1, 2-pentanediol, ethylhexyl glycerol, and arginine/lysine polypeptide;
the phytotoxin is prepared by compounding the following substances: water, glycerin, Adinandra extract and Hibiscus sabdariffa flower extract;
the seven-fold hyaluronic acid is prepared by compounding the following substances: water, sodium hyaluronate crosspolymer, sodium hyaluronate, 1, 2-hexanediol, phenoxyethanol, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, hydrolyzed glycosaminoglycans, hyaluronic acid, and hydroxypropyl trimethylammonium chloride hyaluronic acid.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111667281.2A CN114306128A (en) | 2021-12-31 | 2021-12-31 | Anti-aging and anti-firming composition and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111667281.2A CN114306128A (en) | 2021-12-31 | 2021-12-31 | Anti-aging and anti-firming composition and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN114306128A true CN114306128A (en) | 2022-04-12 |
Family
ID=81021331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111667281.2A Pending CN114306128A (en) | 2021-12-31 | 2021-12-31 | Anti-aging and anti-firming composition and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114306128A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115006308A (en) * | 2022-06-23 | 2022-09-06 | 美卡素大健康产业(广东)有限公司 | Anti-aging careful essence |
CN115054563A (en) * | 2022-08-05 | 2022-09-16 | 广州安若希医药科技有限公司 | Polypeptide repairing composition and preparation method thereof |
CN115300611A (en) * | 2022-08-19 | 2022-11-08 | 山东大学 | Hyaluronic acid-conotoxin polypeptide conjugate and application thereof in preparation of skin products |
CN115350113A (en) * | 2022-07-04 | 2022-11-18 | 广州环亚化妆品科技股份有限公司 | Composition containing peptide and application thereof |
CN115607475A (en) * | 2022-09-15 | 2023-01-17 | 广州市小谭科技有限公司 | Anti-aging and anti-wrinkle composite polypeptide composition and application thereof |
CN115778881A (en) * | 2023-02-02 | 2023-03-14 | 露乐健康科技股份有限公司 | Soothing, moisturizing and refreshing skin care composition, preparation method and application |
CN115813806A (en) * | 2022-12-07 | 2023-03-21 | 广州真如化妆品有限公司 | Lip and cheek dual-purpose liquid with effects of enlarging lips and firming apple muscles and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111297753A (en) * | 2019-12-26 | 2020-06-19 | 济南霜叶红生物科技有限公司 | Anti-aging and weight-losing tightening essence |
CN111658565A (en) * | 2020-06-30 | 2020-09-15 | 广州市瑞芬化妆品有限公司 | Easily-absorbed anti-wrinkle tightening essence and preparation method thereof |
-
2021
- 2021-12-31 CN CN202111667281.2A patent/CN114306128A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111297753A (en) * | 2019-12-26 | 2020-06-19 | 济南霜叶红生物科技有限公司 | Anti-aging and weight-losing tightening essence |
CN111658565A (en) * | 2020-06-30 | 2020-09-15 | 广州市瑞芬化妆品有限公司 | Easily-absorbed anti-wrinkle tightening essence and preparation method thereof |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115006308A (en) * | 2022-06-23 | 2022-09-06 | 美卡素大健康产业(广东)有限公司 | Anti-aging careful essence |
CN115006308B (en) * | 2022-06-23 | 2023-06-20 | 美卡素大健康产业(广东)有限公司 | Reverse age fine anti-aging essence |
CN115350113A (en) * | 2022-07-04 | 2022-11-18 | 广州环亚化妆品科技股份有限公司 | Composition containing peptide and application thereof |
CN115054563A (en) * | 2022-08-05 | 2022-09-16 | 广州安若希医药科技有限公司 | Polypeptide repairing composition and preparation method thereof |
CN115054563B (en) * | 2022-08-05 | 2023-09-05 | 广州安若希医药科技有限公司 | Polypeptide repairing composition and preparation method thereof |
CN115300611A (en) * | 2022-08-19 | 2022-11-08 | 山东大学 | Hyaluronic acid-conotoxin polypeptide conjugate and application thereof in preparation of skin products |
CN115300611B (en) * | 2022-08-19 | 2024-05-28 | 山东大学 | Hyaluronic acid-conoid polypeptide conjugate and application thereof in preparation of skin products |
CN115607475A (en) * | 2022-09-15 | 2023-01-17 | 广州市小谭科技有限公司 | Anti-aging and anti-wrinkle composite polypeptide composition and application thereof |
CN115813806A (en) * | 2022-12-07 | 2023-03-21 | 广州真如化妆品有限公司 | Lip and cheek dual-purpose liquid with effects of enlarging lips and firming apple muscles and preparation method thereof |
CN115778881A (en) * | 2023-02-02 | 2023-03-14 | 露乐健康科技股份有限公司 | Soothing, moisturizing and refreshing skin care composition, preparation method and application |
CN115778881B (en) * | 2023-02-02 | 2023-05-02 | 露乐健康科技股份有限公司 | Skin care composition capable of relieving, moisturizing and refreshing, preparation method and application |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN114306128A (en) | Anti-aging and anti-firming composition and preparation method thereof | |
KR102265730B1 (en) | cosmetic composition for skin wrinkle improvement and whitening facial skin | |
CN107496278A (en) | Carnosine snow face frost | |
CN113616566B (en) | Skin care essence for tightening skin and preparation method thereof | |
CN106236675B (en) | Skin care matrix with moisturizing and anti-aging effects and preparation and application thereof | |
CN109620748B (en) | Anti-wrinkle essence and preparation method thereof | |
CN1985791B (en) | Preparing process of skin care silk protein gel cream | |
CN103585097B (en) | Epidermal growth factor-loaded bletilla rhizome polysaccharide compound, and preparation method and application thereof | |
CN106727148A (en) | Facial mask and preparation method thereof is repaired in a kind of dendrobium candidum moisturizing | |
CN105168054A (en) | Mask capable of supplementing water, whitening and removing wrinkles and preparation method of mask | |
CN103385820B (en) | Repair eye cream | |
CN111603434B (en) | Composition for improving skin wrinkles and cosmetic thereof | |
CN110237006B (en) | Skin care composition and mask | |
CN105832588A (en) | Without-make-up essence composite cream and liquid | |
CN111265457A (en) | Whitening and freckle removing essence composition and preparation method thereof | |
CN110496067A (en) | A kind of anti-wrinkle composition and its preparation method and application | |
CN111249195B (en) | Refreshing astringent lotion and preparation method thereof | |
CN104288066A (en) | Smoothing toner and preparation method thereof | |
CN115006308A (en) | Anti-aging careful essence | |
CN111568797A (en) | Composition for quickly removing fine lines and application thereof | |
CN107320357B (en) | Cosmetic containing polysaccharide | |
CN111973501A (en) | Ceramide activation milk and preparation method thereof | |
CN112716842A (en) | Organic moisturizing cream with long-acting moisturizing effect and preparation method thereof | |
CN112043659A (en) | Anti-wrinkle repair essence cream | |
CN113332196A (en) | Green tea polyphenol repair gel for deep skin repair and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220412 |