CN115054563B - Polypeptide repairing composition and preparation method thereof - Google Patents

Abstract

The application relates to the field of skin care products, and particularly discloses a polypeptide repairing composition and a preparation method thereof. Wherein the polypeptide repair composition comprises the following components: an extract of Pueraria lobata (Willd.) Ohwi; an extract of Dioscorea longa; an extract of cornus officinalis; a euglena gracilis polysaccharide; a polypeptide; a humectant; and (3) a solvent. The preparation method comprises the following steps: the components are added in a certain sequence at a specific temperature and are uniformly mixed, so that the polypeptide repairing composition is obtained. The composition provided by the application has the advantages that the composition is suitable for oily skin people, and is not easy to cause excessive secretion of skin grease while repairing skin barrier; in addition, the preparation method of the application has the advantages of simple and convenient preparation and easy industrialized production.

Description

Polypeptide repairing composition and preparation method thereof

Technical Field

The application relates to the field of skin care products, in particular to a polypeptide repairing composition and a preparation method thereof.

Background

The broad sense of skin barrier includes physical barrier, pigment barrier, nerve barrier and immune barrier, so far we are always referring to skin barrier, mainly physical barrier.

The physical barrier is composed of sebum membrane, keratin of horny layer, lipid, sandwich structure, brick wall structure, dermis mucopolysaccharide, etc., and has effects of resisting external harmful substances, irritants, sunlight, keeping moisture, and regulating antiinflammatory. Skin physical barrier damage causes skin dryness, skin aging, skin sensitivity such as pigmentation atopic dermatitis, eczema, psoriasis, ichthyosis, solar dermatitis, skin greasiness such as irritant dermatitis, and seborrheic diseases such as irritation dependent dermatitis, and therefore, protection and repair of skin barrier have an extremely important role in skin health.

Among them, in the repair of skin barriers, the maintenance of a "brick wall structure" appears to be of paramount importance. The "brick wall" represents keratinocytes, the "mortar" refers to lipids (containing ceramide, fatty acid, cholesterol) in the horny space, the "brick wall" and the "mortar" form a firm structure on the epidermis, limit the water flow inside and outside the cells and between the cells, ensure that the water is not lost, and enable the skin to maintain an important barrier function.

Most of the skin barrier repair products at present generally aim at the problem of the thinning of the horny layer caused by the loss of intercellular lipid in a brick wall structure, and mainly realize the skin barrier repair by supplementing intercellular lipid to thicken the horny layer. This is significant for the congenital population of sensitive muscles with thin horny layer, but for the population of oily skin with partially acquired thin horny layer, the thin horny layer is mainly caused by excessive secretion of skin grease and excessive cleaning for reducing skin grease. When the skin barrier repair product is used, although the problem of repairing the skin barrier is solved temporarily, the problem of unbalance of skin water and oil caused by excessive secretion of skin oil is caused, and therefore, there is still room for improvement.

Disclosure of Invention

In order to make the product of the skin repair barrier more suitable for oily skin, the skin barrier is repaired while the product is not easy to cause water-oil imbalance of the skin, the application provides a polypeptide repair composition and a preparation method thereof.

In a first aspect, the present application provides a polypeptide repair composition, which adopts the following technical scheme:

a polypeptide repairing composition comprises the following components in percentage by mass:

3-6% of wild kudzu root extract;

0.2-0.5% of Dioscorea longa root extract;

3-7% of dogwood extract;

18-22% of Euglena gracilis polysaccharide;

0.15-0.3% of polypeptide;

50-55% of humectant;

the balance being solvent.

Through the synergistic compounding of the wild kudzu root extract, the rhizoma dioscoreae longae extract, the dogwood extract and the fine nude algae polysaccharide extract in the specific proportion, the polypeptide repairing composition is beneficial to better supplementing intercellular lipid, so that the skin stratum corneum is thickened, and the skin barrier is less prone to damage; meanwhile, the compounding of the extracts in the specific proportion is also beneficial to better regulating the water-oil balance of skin and better controlling sebum secretion grease, so that the skin feel of the polypeptide repairing composition is more fresh, the skin is less prone to being too greasy after being used, and the product can be also suitable for people with oily skin.

In addition, the specific proportion of the extract and the humectant are compounded, so that the absorption of skin to moisture is better promoted, the deep water supplementing effect of the skin is better, the water-oil balance of the skin is better regulated, the skin is less prone to continuously secreting grease due to insufficient skin moisture, and the polypeptide repairing composition can be also suitable for oily skin people.

Preferably, the polypeptide is formed by mixing one or more of carnosine, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, sodium pyrrolidone carboxylate and sodium lactate.

Preferably, the polypeptide is prepared by mixing carnosine, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, sodium pyrrolidone carboxylate and sodium lactate according to the mass ratio of 1:0.4-0.6:0.4-0.6:0.4-0.6:1.8-2.3:1.8-2.3.

The polypeptide is formed by adopting the carnosine, the palmitoyl tetrapeptide-7, the palmitoyl pentapeptide-4, the palmitoyl tripeptide-1, the sodium pyrrolidone carboxylate and the sodium lactate which are compounded in a specific proportion, so that the synthesis of skin collagen and hyaluronic acid is better promoted, the reconstruction of a skin barrier is faster, the effect of repairing the skin barrier of the polypeptide repairing composition is better improved, and the anti-allergic and anti-inflammatory effects of the polypeptide repairing composition are better.

Preferably, the polypeptide repair composition further comprises the following components in percentage:

1-1.5% of oat bran extract.

By adding the oat bran extract, the anti-sensitization effect of the polypeptide repairing composition is improved better, the skin barrier is reconstructed better and faster, and meanwhile, the water-oil imbalance caused by excessive secretion of skin grease is not easy to cause, so that the polypeptide repairing composition is more suitable for oily skin people.

Preferably, the humectant comprises one or more of glycerol, butylene glycol, glycine, urea, 1, 2-hexanediol, ethylhexyl glycerol.

Preferably, the humectant is composed of glycerin, butylene glycol, glycine, urea, 1, 2-hexanediol, ethylhexyl glycerin, 16643-16646:7565-7570:18-22:18-22:8-12:1, and mixing the materials according to the mass ratio.

Preferably, the humectant is composed of glycerin, butylene glycol, glycine, urea, 1, 2-hexanediol, ethylhexyl glycerin at 16645:7568:20:20:10:1, and mixing the materials according to the mass ratio.

The glycerin, the butanediol, the glycine, the urea, the 1, 2-hexanediol and the ethylhexyl glycerin which are compounded in a specific proportion are adopted to cooperate as the humectant, so that the skin can be better subjected to deep moisturizing, the skin can be kept tender all the time, the water-oil balance of the skin can be better regulated, the skin is more difficult to excessively secrete grease due to water deficiency, and the polypeptide repairing composition is more suitable for oily skin people.

Preferably, the polypeptide repairing composition further comprises the following components in percentage by mass:

polysorbate-20.003-0.005%.

The polysorbate-20 is added, so that the compatibility of the humectant and other components is better improved, the humectant can better play a role in deep water supplementing, the skin is kept tender all the time, and the skin water-oil balance is better regulated.

In a second aspect, the present application provides a method for preparing a polypeptide repair composition, which adopts the following technical scheme:

a method of preparing a polypeptide repair composition comprising the steps of:

step 1, mixing a solvent, butanediol, glycine, urea and 1, 2-hexanediol, and uniformly stirring and mixing to form a phase A composition;

step 2, raising the temperature to 85-90 ℃, adding glycerol, ethylhexyl glycerol and polysorbate-20, stirring and homogenizing for 10-15min to form a phase B composition;

and 3, reducing the temperature, adding the wild kudzu root extract, the long soft yam root extract, the dogwood extract, the nude algae polysaccharide, the polypeptide and the oat bran extract when the temperature is reduced to be lower than 45 ℃, stirring and mixing uniformly, filtering, and discharging to obtain the polypeptide repairing composition.

By controlling the addition sequence of the components, the components are better mixed and uniformly dispersed, so that the components can better exert the mutual synergistic effect, and the efficacy of the polypeptide repairing composition is more obvious; in addition, the polypeptide repairing composition can be obtained by mixing the substances in a certain sequence at a specific temperature, and the preparation is simple and convenient and is easy for industrial production.

In summary, the application has the following beneficial effects:

1. the polypeptide repairing composition is beneficial to better supplementing intercellular lipid by adopting the synergistic compounding of the wild arrowroot root extract, the long soft yam root extract, the dogwood extract and the fine nude algae polysaccharide extract in a specific proportion, so that the skin cuticle is thickened, and the skin barrier is less prone to damage.

2. The water-oil balance of the skin is better regulated by adopting the specific proportion of the extract for compounding, sebum secretion is better controlled, the skin feel of the polypeptide repairing composition is more fresh, the skin is less greasy after being used, and the product can be also suitable for people with oily skin.

3. The polypeptide is formed by adopting the carnosine, the palmitoyl tetrapeptide-7, the palmitoyl pentapeptide-4, the palmitoyl tripeptide-1, the sodium pyrrolidone carboxylate and the sodium lactate which are compounded in a specific proportion, so that the synthesis of skin collagen and hyaluronic acid is better promoted, the reconstruction of a skin barrier is faster, the effect of repairing the skin barrier of the polypeptide repairing composition is better improved, and the anti-allergic and anti-inflammatory effects of the polypeptide repairing composition are better.

4. The polypeptide repairing composition can be obtained by mixing the substances in a certain sequence at a specific temperature, and has the advantages of simple and convenient preparation and easy industrialized production.

Detailed Description

The present application will be described in further detail with reference to examples.

In the examples below, each of the raw materials was commercially available. Specifically, the CAS number of the kudzu root extract is: 223748-08-1; the CAS number of the Dioscorea longa root extract is: 90147-49-2; the CAS number of the dogwood extract is: 77-52-1; the Euglena parvula polysaccharide is purchased from SiAnhuo biosciences, and the model is XAQN-00181; oat bran extract was purchased from volcanic biotechnology limited, lanzhou.

Example 1

The embodiment of the application discloses a polypeptide repairing composition which comprises the following components in parts by mass:

3kg of kudzu root extract; 0.2kg of Dioscorea longa root extract; 3kg of dogwood extract; 18kg of Euglena parvula polysaccharide; 0.15kg of polypeptide; 50kg of humectant; 25.65kg of solvent.

In this embodiment, the polypeptide is formed by mixing carnosine, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, sodium pyrrolidone carboxylate and sodium lactate in a mass ratio of 1:0.4:0.4:0.4:1.8:1.8; the humectant is prepared from glycerol, butanediol, glycine, urea, 1, 2-hexanediol, and ethylhexyl glycerol at 16643:7565:18:18:8:1, mixing the materials according to the mass ratio; the solvent is water.

The embodiment of the application also discloses a preparation method of the polypeptide repairing composition, which comprises the following steps:

step 1, cleaning and sterilizing equipment for production, accurately weighing substances with the mass, adding water, butanediol, glycine, urea and 1, 2-hexanediol into a main pot of an emulsifying machine, stirring at a rotating speed of 30r/min, and uniformly stirring and mixing to form the phase A composition.

And 2, raising the temperature to 85 ℃, continuously adding glycerol and ethylhexyl glycerol while stirring, and stirring and homogenizing for 15min at a rotating speed of 3000r/min to form a phase B composition.

And 3, reducing the temperature by stirring under natural conditions, adding the wild kudzu root extract, the long soft yam root extract, the dogwood extract, the nude algae polysaccharide and the polypeptide when the temperature is reduced to below 45 ℃, stirring and mixing uniformly, filtering, and taking out filtrate to obtain the polypeptide repairing composition.

Example 2

The difference from example 1 is that:

the dosage of each component is different, and the specific steps are as follows:

6kg of kudzu root extract; 0.5kg of Dioscorea longa root extract; 7kg of dogwood extract; 22kg of euglena parvula polysaccharide; 0.3kg of polypeptide; 55kg of humectant; 9.2kg of solvent.

In this embodiment, the polypeptide is formed by mixing carnosine, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, sodium pyrrolidone carboxylate and sodium lactate in a mass ratio of 1:0.6:0.6:0.6:2.3:2.3; the humectant is prepared from glycerol, butanediol, glycine, urea, 1, 2-hexanediol, and ethylhexyl glycerol at 16646:7570:22:22:12:1, mixing the materials according to the mass ratio; the solvent is water.

The preparation process parameters of the polypeptide repairing composition are different, and the preparation process comprises the following steps:

in the step 2, the temperature is increased to 90 ℃, and the stirring and homogenizing time is controlled to be 10min.

Example 3

The difference from example 1 is that:

the dosage of each component is different, and the specific steps are as follows:

4.5kg of kudzu root extract; 0.3kg of Dioscorea longa root extract; 5kg of dogwood extract; 20kg of euglena parvula polysaccharide; 0.2kg of polypeptide; 53kg of humectant; 17kg of solvent.

In this example, the polypeptide is formed by mixing carnosine, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, sodium pyrrolidone carboxylate and sodium lactate in a mass ratio of 1:0.5:0.5:0.5:2:2; the humectant is prepared from glycerol, butanediol, glycine, urea, 1, 2-hexanediol, and ethylhexyl glycerol at 16645:7568:20:20:10:1, mixing the materials according to the mass ratio; the solvent is water.

The preparation process parameters of the polypeptide repairing composition are different, and the preparation process comprises the following steps:

in the step 2, the temperature is increased to 88 ℃, and the stirring and homogenizing time is controlled to be 12min.

Example 4

The difference from example 3 is that: the humectant replaces glycerin with an equivalent amount of allantoin.

Example 5

The difference from example 3 is that: the humectant replaces butanediol with an equivalent amount of allantoin.

Example 6

The difference from example 3 is that: the humectant replaces urea with an equivalent amount of allantoin.

Example 7

The difference from example 3 is that:

the polypeptide repairing composition also comprises the following components in mass:

1kg of oat bran extract; polysorbate-20.003kg. The amount of water was adjusted to 15.997kg.

Wherein, polysorbate-20 is added and mixed with glycerin and ethylhexyl glycerin in the step 2; the oat bran extract is added with other plant extracts and stirred and mixed in the step 3.

Example 8

The difference from example 3 is that:

the polypeptide repairing composition also comprises the following components in mass:

1.5kg of oat bran extract; polysorbate-20.005 kg. The water usage was adjusted to 15.495kg.

Wherein, polysorbate-20 is added and mixed with glycerin and ethylhexyl glycerin in the step 2; the oat bran extract is added with other plant extracts and stirred and mixed in the step 3.

Comparative example 1

The difference from example 3 is that: the extract of Pueraria lobata is replaced by the same amount of herba Portulacae extract.

Comparative example 2

The difference from example 3 is that: the asiatic centella extract is used to replace the root extract of Dioscorea longa.

Comparative example 3

The difference from example 3 is that: the dogwood extract is replaced by the equivalent swertia japonica extract.

Comparative example 4

The difference from example 3 is that: the same amount of ginkgo leaf polysaccharide is used to replace the Euglena gracilis polysaccharide.

Application example 1

The application example of the application discloses essence containing the polypeptide repairing composition, which comprises the following components in mass:

4kg of glycerol; 3.522kg of propylene glycol; sodium hyaluronate 0.2kg; glycerol polyether-26 kg; panthenol 0.5kg; 0.006kg of glycerol octanoate; octanoyl hydroxamic acid 0.072kg; 4.5kg of polypeptide repairing composition; 85.2kg of water.

In this example, the polypeptide repair composition is the polypeptide repair composition prepared in example 1.

The application example of the application also discloses a preparation method of the essence containing the polypeptide repairing composition, which comprises the following steps:

step 1, cleaning and sterilizing production equipment, accurately weighing substances with the mass, adding water, glycerol, 3kg of propylene glycol, sodium hyaluronate, glycereth-26 and panthenol into a main pot of an emulsifying pot, heating to 85 ℃, stirring and mixing uniformly at a rotating speed of 30r/min, and homogenizing for 10min at a rotating speed of 3000r/min to completely dissolve and disperse the raw materials uniformly to form the phase A composition.

And 2, maintaining the temperature of 85 ℃ and continuously stirring at the rotating speed of 30r/min for 30min, reducing the temperature by continuously stirring under natural conditions after the raw materials in the emulsifying pot are defoamed, adding the polypeptide repairing composition when the temperature is reduced to be below 45 ℃, and continuously stirring for 15min to form the phase B composition.

And 3, continuously stirring while adding glycerol caprylate, octanoyl hydroxamic acid and the rest propylene glycol, continuously stirring for 15min, filtering, and discharging to obtain the essence containing the polypeptide repairing composition.

Application example 2

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 2.

Application example 3

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 3.

Application example 4

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 4.

Application example 5

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 5.

Application example 6

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 6.

Application example 7

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 7.

Application example 8

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the example 8.

Comparative application example 1

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the comparative example 1.

Comparative application example 2

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in comparative example 2.

Comparative application example 3

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in the comparative example 3.

Comparative application example 4

The difference from application example 1 is that: the polypeptide repairing composition is the polypeptide repairing composition prepared in comparative example 4.

Experiment 1

The hyaluronidase inhibition ratio (%) of the polypeptide-modified composition prepared in the above examples and comparative examples was measured according to the "hyaluronidase inhibition experiment-Elson-Morgan modification method".

The higher the inhibition rate of the hyaluronidase obtained by detection, the better the anti-sensitization effect of the polypeptide repairing composition is shown.

Experiment 2

Randomly selecting 120 female volunteers with oily skin and face having allergic problems such as itching or red swelling, wherein the age range is 25-40 years, randomly dividing the volunteers into 12 groups of 10 people, respectively and correspondingly using the essence prepared by the application examples and the comparative application examples after cleaning the face in the morning and evening, taking 5g each time, uniformly smearing the essence on two sides of cheeks, adhering to 28 days of use, observing and recording the use effect condition, and carrying out the following detection on the volunteers:

detection 1

The time (days) for complete regression of itching and redness on the face after the application of the serum was recorded for the same group of volunteers, and the average (days) of the time of use for complete regression of itching and redness was calculated and recorded for the same group of volunteers.

Detection 2

After each group of volunteers adhere to the essence for 28 days and the allergic conditions of skin itch and red swelling completely subside, after the 29 th day of facial cleansing of the volunteers, detecting the oil content of the skin surface of each group of volunteers by using a skin oil tester of the model SM815-MPA of German CK, and calculating the average value of the detection values of the volunteers in the same group to obtain the skin oil content before the essence is used; meanwhile, the skin moisture content of each volunteer is detected by using a skin moisture tester of the model CM825-MDD of German CK, and the average value of the detection values of the volunteers in the same group is calculated to obtain the skin moisture content before the essence is used.

After the volunteers of each group are cleaned, respectively and correspondingly taking the essence prepared by the application examples and the comparative application examples, taking the amount of 5g, after the volunteers use the essence for 8 hours (no other cosmetics or skin care products are used in the period, and the volunteers 8 hours are all still sitting in a room with the constant temperature of 27 ℃), detecting the oil content of the skin of each group of volunteers by using a skin oil tester with the model of SM815-MPA of German CK, and calculating the average value of the detection values of the volunteers of the same group to obtain the skin oil content after the essence is used; meanwhile, after the volunteers use the essence for 3h, 8h and 12h (without using any other cosmetics or skin care products during the period, and the volunteers were all sitting still in a room with room temperature constant temperature of 27 ℃), the skin moisture content of each volunteer was detected by using a skin moisture tester of the model CM825-MDD of germany CK again, and the average value of the detection values of the volunteers of the same group was calculated to obtain the skin moisture content after the use of the essence for 3h, after the use of the essence for 8h and after the use of the skin moisture content for 12h, respectively.

Finally, the rate of change (%) of the oil content of the skin surface of the volunteer before and after the use of the serum was calculated and recorded.

The change rate of the oil content on the skin surface is calculated as follows:

the test data of experiment 1 above are detailed in table 1.

TABLE 1

The test data of experiment 2 above are detailed in table 2.

TABLE 2

According to the data comparison of the embodiment 3 and the comparative examples 1-4 in the table 1 and the table 2, only by adopting the synergistic compounding of the kudzu root extract, the dioscorea nipponica Makino extract, the dogwood extract and the euglena polysaccharide in specific proportions, the skin water-oil balance can be better regulated while the skin barrier is repaired, the deep water supplementing and water locking of the skin can be more effective, the skin is less prone to continuously excrete grease due to insufficient water, the polypeptide repairing composition is more suitable for people with oily skin, the oil control effect and the water-oil balance effect of the polypeptide repairing composition are easily influenced greatly when any substance is replaced, and the problems of excessive skin secretion grease and acne and the like are easily caused when the product is used by people with oily skin are easily caused when the skin barrier is repaired.

According to the data comparison of examples 3-6 in Table 1 and Table 2, only by adopting glycerin, butanediol, glycine, urea, 1, 2-hexanediol and ethylhexyl glycerin which are compounded in a specific proportion as a humectant, the skin can be better subjected to deep water supplementing, and the water supplementing effect is longer lasting and long-acting, so that the skin is less prone to continuously secreting grease due to water deficiency, the skin barrier is restored, the skin is kept fresh, any substance is replaced, and the oil control effect of the polypeptide repairing composition is easily influenced greatly.

According to the comparison of the data of examples 3 and 7-8 in tables 1 and 2, by adding oat bran extract and polysorbate-20, it is advantageous to improve the hyaluronidase inhibition rate of the polypeptide repairing composition to a certain extent, and to supplement skin moisture deeply to a certain extent, so that the balance of skin water and oil is easier to regulate.

The above embodiments are not intended to limit the scope of the present application, so: all equivalent changes in structure, shape and principle of the application should be covered in the scope of protection of the application.

Claims (3)

1. A polypeptide repair composition, characterized by: comprises the following components in percentage by mass:

3-6% of wild kudzu root extract;

0.2-0.5% of Dioscorea longa root extract;

3-7% of dogwood extract;

18-22% of Euglena gracilis polysaccharide;

0.15-0.3% of polypeptide, wherein the polypeptide is prepared by mixing carnosine, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, palmitoyl tripeptide-1, sodium pyrrolidone carboxylate and sodium lactate according to the mass ratio of 1:0.4-0.6:0.4-0.6:0.4-0.6:1.8-2.3:1.8-2.3;

50-55% of a humectant, wherein the humectant is prepared from glycerin, butylene glycol, glycine, urea, 1, 2-hexanediol, and ethylhexyl glycerin according to 16643-16646:7565-7570:18-22:18-22:8-12:1, mixing the materials according to the mass ratio;

1-1.5% of oat bran extract;

polysorbate-20.003-0.005%;

the balance being solvent.

2. A polypeptide repair composition according to claim 1 characterized in that: the humectant consists of glycerin, butanediol, glycine, urea, 1, 2-hexanediol and ethylhexyl glycerin according to 16645:7568:20:20:10:1, and mixing the materials according to the mass ratio.

3. A method of preparing the polypeptide repair composition of claim 1 or 2, characterized by: the method comprises the following steps:

step 1, mixing a solvent, butanediol, glycine, urea and 1, 2-hexanediol, and uniformly stirring and mixing to form a phase A composition;

step 2, raising the temperature to 85-90 ℃, adding glycerol, ethylhexyl glycerol and polysorbate-20, stirring and homogenizing for 10-15min to form a phase B composition;

and 3, reducing the temperature, adding the wild kudzu root extract, the long soft yam root extract, the dogwood extract, the nude algae polysaccharide, the polypeptide and the oat bran extract when the temperature is reduced to be lower than 45 ℃, stirring and mixing uniformly, filtering, and discharging to obtain the polypeptide repairing composition.