CN108420780A - A kind of cosmetic composition of bright color and its application - Google Patents
A kind of cosmetic composition of bright color and its application Download PDFInfo
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- CN108420780A CN108420780A CN201810627511.4A CN201810627511A CN108420780A CN 108420780 A CN108420780 A CN 108420780A CN 201810627511 A CN201810627511 A CN 201810627511A CN 108420780 A CN108420780 A CN 108420780A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of cosmetic compositions of bright color, and it includes the yushanias of (A) 30 95 wt%（BAMBUSA VULGARIS）Water, common ingredient in the brewer's yeast lysate filtrate of (B) 0.01 30wt%, and (C) optional skin protection cosmetics, wherein the cosmetic composition of the bright color of the present invention does not include the water added usually as independent component.Through overtesting, the inventors discovered that, yushania（BAMBUSA VULGARIS）Water significantly promotes the transdermal absorption factor of brewer's yeast lysate filtrate, and active constituent is easier to be absorbed by the skin, and has the effect of better bright color.
Description
Technical field
The invention belongs to cosmetic field, the cosmetic composition more particularly to a kind of bright color and its application.
Background technology
The dark yellow skin problem of the colour of skin is that the natural gloss of health can not be shown.The reason for causing skin dark yellow has very
It is more, for example have not enough sleep and affect the metabolic function of skin, it causes aging, cuticula to thicken, causes skin to lose transparent
Sense occurs dark and gloomy；Because face cleaning, which is not thorough, makes the formation dirt mixed in together such as sebum and dust, oxidation deterioration, if after
Ultraviolet light is touched in continued access, will form peroxide lipid, has upset the rhythm of the metabolism of skin, to make the low and deep nothing of skin
Light；In addition, as smoking can lead to ascorbic destruction and loss, ultraviolet light and life are irregular to lead to internal cell hypoxia, loses
Dormancy, pressure, anxiety etc. can all cause the colour of skin low and deep unglazed.
Invention content
The technical problem to be solved in the present invention is to provide a kind of cosmetic composition of bright color, active constituent be easy to by
Skin absorbs, and supplements the nutrients, and improves pigementation and the colour of skin is uneven, have the function of bright color.
The specific technical solution for solving above-mentioned technical problem is as follows：
A kind of cosmetic composition of bright color, it includes the yushania (BAMBUSA of (A) 30-95wt%
VULGARIS) water, the brewer's yeast lysate filtrate of (B) 0.1-30wt% and (C) are optional, in skin protection cosmetics common
Ingredient, wherein the cosmetic composition of the bright color of the present invention does not include the water added usually as independent component.
Further, the composition also includes the Rhizoma Seu Herba Bergeniae (BERGENIA of (D) 0.1-5wt%
CRASSIFOLIA) broom top (SAROTHAMNUS SCOPARIUS) extract, (F) 1- of root extract, (E) 1-10wt%
The inositol of Fructus Malvae Vertillatae (MALVA VERTICILLATA) extract and (G) 0.1-5wt% of 10wt%.
The cosmetic composition of the present invention can notable bright color.
The skin care cosmetic compositions of the present invention do not include any additional water, but are not excluded for used yushania
A small amount of or trace the water unavoidably introduced in intrinsic moisture and other ingredients in (BAMBUSA VULGARIS) water.
In preferred embodiments, edta salt, more phosphorus are not added in the cosmetic composition of bright color of the invention
The chelating agents such as sour sodium, sodium metaphosphate, gluconic acid.
The invention further relates to a kind of methods for the transdermal absorption factor increasing brewer's yeast lysate filtrate, including will be leading
Bamboo (BAMBUSA VULGARIS) water is added to the makeup for the bright color for not including water comprising brewer's yeast lysate filtrate
In product composition.The method is remarkably improved the transdermal absorption factor of brewer's yeast lysate filtrate, to be embodied as skin
It supplements the nutrients, improves endocrine.
The present invention also relates to the compositions of yushania (BAMBUSA VULGARIS) water and brewer's yeast lysate filtrate
Purposes in the cosmetic composition of the bright color not comprising water.
Involved this section of leading Sinobambusa standing grain le Sinobambusa, component (A) yushania (BAMBUSA in the present invention
VULGARIS) then water uses conventional method to sterilize, obtains water white transparency, without heavy by squeezing to obtain fresh leading bamboo
It forms sediment, no-sundries, there is the fragrant and nutritious abundant juice of bamboo.Yushania (BAMBUSA VULGARIS) water acquired without
Radiation treatment does not add preservative, to retain the nutritional ingredient of yushania (BAMBUSA VULGARIS) water to greatest extent.
Component (B) the brewer's yeast lysate filtrate, thalline vitamin, protein content are high, can eat, is medicinal
And fodder yeast, it can also be from wherein extraction cromoci, nucleic acid, glutathione, thromboplastinum, coacetylase and atriphos etc.
Useful component；Brewer's yeast lysate filtrate can rapid osmotic to cuticula hereinafter, providing useful nutritional ingredient for skin.
Component (D) Rhizoma Seu Herba Bergeniae scientific name Bergenia crassifolia (L.) Fritsch is Saxifragaceae rock
Chinese cabbage category perennial evergreen draft, it is sweet in flavor, puckery, it is cool in nature, enter liver, lung, the spleen channel；With antibechic, anti-inflammatory, liver protection, eliminate free radical
Etc. multiple efficacies.
Component (E) broom top (Latin literary fame：Parochetus communis) also known as：Peacock flower is pulse family, purple
Sparrow flower belongs to draft of crawling, and taste sweet, warm enters liver, spleen two passes through；With strengthening by means of tonics, the effect of promoting blood circulation for regulating menstruation, expelling wind and removing dampness, invigorating the spleen.
Component (F) Fructus Malvae Vertillatae (MALVA VERTICILLATA) is the drying and ripening of Malvaceae mallow winter certain herbaceous plants with big flowers
Fruit, it is sweet in flavor, puckery, it is cool in nature, enter Return liver, large intestine, bladder warp；With reducing fever and causing diuresis, detumescence and other effects.
Component (G) inositol is a kind of inositol type monosaccharide that distributed pole is wide, has biotin as vitamin B
Effect, moisturizing nutritious to skin and conditioning functions.
The cosmetic composition of the bright color of the present invention may include the yushania (BAMBUSA of 30-95wt%
VULGARIS) water, preferably 51-81wt% are calculated with the total weight of the composition.
The cosmetic composition of the bright color of the present invention may include the brewer's yeast lysate filtrate of 0.1-30wt%,
It is preferred that 2-20wt%, is calculated with the total weight of the composition.
The present invention bright color cosmetic composition also optionally include component (C) skin protection cosmetics in commonly at
Point, including medium, active constituent, surfactant and auxiliary material etc..Component (C) is known in the art, this field skill
Art personnel can be specifically chosen its type and dosage as needed.In general, the content of component (C) in the compositions of the present invention is 0-
65wt%, the total weight based on the composition calculate.
The medium is, for example, diluent, dispersant or carrier etc..All these mediums be all it is known in the art,
Those skilled in the art can be specifically chosen its type and dosage as needed.For example, the medium include but not limited to ethyl alcohol,
Dipropylene glycol, butanediol etc..In general, in the compositions of the present invention, the medium accounts for the 0.5-20% of component (C) total weight.
The active constituent includes such as emollient, moisturizer, skin conditioning agent.All these active constituents are all these
Known to field, those skilled in the art can be specifically chosen its type and dosage as needed.
For example, the emollient includes but not limited to olive oil, macadimia nut oil, Sweet Almond Oil, grape seed oil, crocodile
Pear oil, corn oil, sesame oil, soybean oil, peanut oil, white pond flower seed oil, safflower seed oil, dog rose fruit oil, thorn A Gan tree benevolence
The auspicious palmitic acid fruit oil of oil, jojoba seed oil, sunflower seed oil, hair, saualane, ethylhexyl palmitate, isopropyl myristate, hydrogenation
Polyisobutene, isohexadecane, Jojoba esters, dimethyl silicone polymer, Permethyl 99A, diethyl hexylcarbonate, carbonic acid two are pungent
Ester, Hamposyl L isopropyl ester, isononyl isononanoate, Nexbase 2004, glycerine three (thylhexoic acid) ester, cetanol ethyl hexyl
Acid esters, double-diethoxy diethylene glycol (DEG) hexamethylene 1,4- dicarboxylic esters, caprylic/capric triglyceride, oleyl alcohol eruciate, octyl ten
Glycol myristinate, octyl dodecanol, dimethyl silicone polymer, octyl polymethyl siloxane, cetyl polydimethylsiloxanes
Alkane, ring five dimethyl silicone polymer etc. it is one or more.Solid emollient of the present invention include but not limited to cetanol,
Stearyl alcohol, cetostearyl alcohol, docosyl alcohol, batyl alcohol, lauric acid, Butyrospermum parkii fruit fat, myristic acid, palmitic acid, stearic acid, bee
Wax, candelila wax, Brazil wax, lanolin, ceresine, Jojoba seed wax, paraffin, microwax, hydrogenated rice bran wax, hydrogenated coco
The acid esters of glyceride type, glyceryl behenate/20, myristyl alcohol myristinate, the more acyl group adipate esters -2 of double-two glycerine,
It is one or more in Butyrospermum parkii fruit fat, wooden Shandong star fruit palm fibre seed fat etc..The content of the emollient in the composition is
It is known in the art.In general, in the compositions of the present invention, the emollient accounts for the 1-50% weight of component (C) total weight.
For example, the moisturizer include but not limited to glycerine, diglycerol, propylene glycol, 1,3-PD, 1,2- pentanediols,
Polyethylene glycol-8, polyethylene glycol -32, methyl gluceth -10, methyl gluceth -20, PEG/PPG-17/6 copolymerization
Object, glycerin polyether -7, glycerin polyether -26, glycosylglycerol, PPG-10 methyls ether, PPG-20 methyls ether, PEG/
- 8/5/3 glycerine of PPG/ polytetramethylene glycols, sucrose, trehalose, rhamnose, mannose, gossypose, glycine betaine, erythrite, xylitol,
Biological carbohydrate gum -2, urea, -5 lactate of glycerin polyether, Sodium Hyaluronate, polyglutamic acid sodium, hydrolysis Scleroglucan, the short stalk of budding
It is one or more in enzyme polysaccharide, tremella polysaccharides, tamarind seed polysaccharide etc..The content of the moisturizer in the composition is this
Known to field.In general, in the compositions of the present invention, the moisturizer accounts for the 1-30% weight of component (C) total weight.
The skin conditioning agent may include for the active constituent with moisturizing, crease-resistant, nti-freckle, anti-acne, oil-control and other effects,
Including but not limited to kojic acid, ascorbic acid, ascorbic acid glucoside, ursin, Trenaxmine, niacinamide, phytosterol, plant steroid
Alcohol/docosyl alcohol/octyl decanol lauroyl glutamate ester, Symwhite-337, turmeric root extract, extraction from betula plaryphylla,
Cer NS, Cer NP, acetyl phytosphingosine, dipotassium glycyrrhizinate, allantoin, resveratrol, the extraction of rosewood bark
Object, Coleus forskohlii root extract, pepper seed extract, ubiquinone, cholesterine, Cholesteryl stearate, two palm of ascorbic acid
Acid esters, tocopherol (vitamin E), tocopherol acetate, red does not have pentaerythritol tetra (di-tert-butyl hydroxy hydrocinnamate)
Medicine alcohol, Ascorbyl Tetraisopalmitate, pyridoxine dicaprylate, pyridoxine dipalmitate, retinyl palmitate, plant
Sterol/octyl dodecanol lauroyl glutamate ester, double-docosyl alcohol/isooctadecanol/phytosterol dimerization Asia oleyl alcohol dimerized linoleic acid
It is one or more in ester, phytosterol Queensland nut oleate, various peptides, each Plant Extracts etc..The skin tune
It is known in the art to manage the content of agent in the composition.In general, in the compositions of the present invention, the skin conditioning agent accounts for
The 0.01-50% weight of component (C) total weight.
The auxiliary material includes but not limited to surfactant, emulsifier, thickener, preservative, fragrance, pH adjusting agent etc..
All these adjunct ingredients are all known in the art, and those skilled in the art can be specifically chosen its type and use as needed
Amount.
The surfactant for reducing interface surface tension, reach cleaning, emulsification, stabilising system purpose,
It can be commonly used for any kind of surfactant of cosmetics, those skilled in the art can be according to required its type of selection
And dosage.For example, the surfactant may include but be not limited to fatty acid soaps (such as sodium laurate, sodium palmitate etc.), height
Grade alkyl sulfate (such as NaLS etc.), alkyl ether sulfate (such as PEG- triethanolamine lauryl sulfates, PEG-
NaLS etc.), N- acyl groups sarcosine (such as sodium N-lauroyl sarcosinate etc.), higher fatty acid amides sulfonate (example
Such as lauryl methyl sodium taurocholate), alkylbenzene sulfonate, high-grade aliphatic ester sulfate (for example, hardening coco-nut oil fatty acid
Glycerine sodium sulphate etc.), N- acyl glutamates, alpha-alkene sulfonate, lauryl dimethyl amine oxyneurine, alkyl betaines
Alkali, amido betaines, sulfobetaines, sorbitan fatty acid esters class (for example, dehydrated sorbitol mono-fatty acid ester,
Sorbitan list isostearate, sorbitan monolaurate, span 40, dehydration mountain
Pears sugar alcohol monostearate, NOFABLE SO-992, glycerine polyglyceryl fatty acid ester class are (for example, single erucic acid glycerine
Ester, sesquialter olein, glycerin monostearate, glycerol monostearate malate etc.), methyl glycol fatty acid ester class (example
Such as, propylene glycolmonostearate etc.), rilanit special derivative, glycerine alkyl ether etc., PEG sorbitan fatty acid esters (examples
Such as, PEG- D-sorbites monolaurate, PEG- sorbitol monooleates, PEG- sorbitan monostearates etc.), PEG-
Glycerine fatty acid esters (for example, PEG- glyceryl monostearates, PEG- glycerol monoisostearates etc.), PEG- fatty acid esters
(for example, PEG- distearates, diglycol stearate etc.), PEG- alkyl ethers (such as PEG-2- octyldodecyls
Ether etc.), PEG- castor oil hardened castor oil derivative is (for example, PEG- rilanit specials, PEG- rilanit special list isostearic acids
Ester, PEG- hardened castor oil maleic acids etc.), sucrose fatty ester etc..The content of the surfactant containing in the composition
Amount is known in the art.In general, in the compositions of the present invention, the surfactant accounts for the 1-50% of component (C) total weight
Weight.
For example, the emulsifier includes but not limited to cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, poly- mountain
Pears alcohol ester -60, Polyoxyethylene Sorbitan Monooleate, methyl sesquistearate, PEG-20 methyls sesquistearate, PEG-
40 rilanit specials, PPG-26- butylol polyethers -26, -2 stearate of PEG-4 polyglycereol, PEG-60 rilanit specials, stearyl alcohol
Polyethers -2, stereth -21, PPG-13- decyl tetradecyl alcohols polyethers -24, cetearyl glucoside, PEG-100 stearic acid
Ester, stearine, stearine SE, cocoyl glucoside, ceteareth -25, PEG-40 stearates,
Polyglycereol-3-methyl distearate, Glyceryl stearate citrate, Natrulon H-10 stearate, Natrulon H-10 meat
Myristate, Natrulon H-10 dioleate, Natrulon H-10 laurate, Natrulon H-10 isostearate, Natrulon H-10 oil
Acid esters, Natrulon H-10 diisopstearate, -6 laurate of polyglycereol, -6 myristinate of polyglycereol, sucrose distearyl acid
It is one or more in ester, Sucrose Polystearic Acid Esters etc..The content of the emulsifier in the composition is known in the art
's.In general, in the compositions of the present invention, the emulsifier accounts for the 0.5-10% weight of component (C) total weight.
For example, the thickener include but not limited to Carbomer, acrylic acid (ester) class and its derivative, xanthans, Ah
Draw primary glue, polyethylene glycol -14M, polyethylene glycol -90M, succinoglycan, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl
It is one or more in the high molecular polymers such as methylcellulose.The content of the thickener in the composition is this field
It is known.In general, in the compositions of the present invention, the thickener accounts for the 0.1-10% weight of component (C) total weight.
For example, the preservative include but not limited to methyl hydroxybenzoate, Nipasol, Phenoxyethanol, benzyl alcohol, benzyl carbinol,
It is one or more in Bis(hydroxymethyl)imidazolidinyl urea, potassium sorbate, sodium benzoate, Chlorphenesin, dehydroactic acid sodium etc..Institute
It is known in the art to state the content of preservative in the composition.In general, in the compositions of the present invention, the preservative accounts for
The 0.01-2% weight of component (C) total weight.
The pH adjusting agent includes but not limited to arginine, citric acid, tromethamine, sodium citrate, sodium hydroxide, hydrogen-oxygen
Change potassium etc..
The cosmetic composition of the bright color of the present invention can be prepared by any suitable method known in the art.
For example, the containers such as common dissolving tank in cosmetic field, emulsification pot, disperser, delivery pump can be used to prepare.When preparation,
Water-soluble substances are first put into aqueous phase dissolved kettle, oil soluble material is put into oil phase dissolution kettle, respectively adds the temperature of two kettles
Heat is to 80 DEG C or so, can be first pre-dispersed by its with disperser wherein for the raw material easily to lump.After the completion of to be dissolved by oil phase and
In water conveying to emulsification pot, emulsifying about 5-15 minutes.Material temperature is down to room temperature after the completion of emulsification, is optionally added perfume (or spice)
Essence, preservative etc., and optionally adjust the pH of product.It can filling shipment after coherent detection index all qualifications.Side made above
Method can require to be deleted or adjusted according to dosage form, can prepare the various dosage forms such as lotion, cream, frost or gel as needed.
In a preferred embodiment, the present invention provides a kind of stoste of bright color, contains following quality percentage
The component (as shown in table 1) of content, the stoste of the bright color have bright color excellent effect.
Table 1
| Ingredient | Content (% weight) |
| Brewer's yeast lysate filtrate | 0.1-30 |
| Inositol | 0.1-5 |
| Rhizoma Seu Herba Bergeniae (BERGENIACRASSIFOLIA) root extract | 0.1-5 |
| Broom top (SAROTHAMNUSSCOPARIUS) extract | 1-10 |
| Fructus Malvae Vertillatae (MALVAVERTICILLATA) extract | 1-10 |
| 1,3- propylene glycol | 5-15 |
| Parahydroxyacet-ophenone | 0.25-0.45 |
| 1,2- hexylene glycols | 1-3 |
| Glycerine | 1-5 |
| Allantoin | 0.01-0.05 |
| Yushania (BAMBUSAVULGARIS) water | Surplus |
Description of the drawings
Fig. 1 is the change rate of the skin brightness of stoste of the present invention.
Specific implementation mode
It is further illustrated the present invention below by specific embodiment, reference examples, it is to be understood that, it is these embodiments, right
It is only used for specifically describing in more detail as usual being used, and is not to be construed as limiting the present invention in any form.
Embodiment 1：The transdermal absorption factor of brewer's yeast lysate filtrate in different systems
In the present embodiment, brewer's yeast lysate filtrate is tested and compares in Aquo System and not Aquo System
Transdermal absorption factor.Specific test formulations see the table below 2.
Table 2
Test method：Using " the rebuilding people's epidermis " obtained by " Human keratinocytes " culture, rebuild on the downside of people's epidermis
There is maintenance culture medium.According to above-mentioned test formulations, yushania (BAMBUSA VULGARIS) water or water are used respectively, by brewer's yeast
Lysate filtrate is configured to 0.5% solution, takes 32ul/cm2Above-mentioned solution be applied to skin model epidermis level respectively,
Start to detect after contacting 8h respectively.Each point do 3 it is parallel.Skin histology is cleaned with phosphate buffer before detection, carries out tissue
It is homogenized, then the brewer's yeast lysate filtrate content being absorbed by tissue by ELISA method detection.Test result see the table below 3.
Table 3
The above result shows that compared with Aquo System, it is not aqueous and containing yushania (BAMBUSA VULGARIS) water
In system, the transdermal absorption factor of brewer's yeast lysate filtrate significantly improves.
Embodiment 2：The skin toner water composition vs. of the present invention compares skin toner water composition
The formula of each skin toner water composition is as shown in table 4 below.
Table 4
Above-mentioned skin toner water composition is prepared as follows：
1. methyl hydroxybenzoate and Phenoxyethanol are mixed and heated to 70 DEG C, stirring and dissolving is uniform.
2. hydroxyethyl cellulose, brewer's yeast lysate filtrate and butanediol are uniformly mixed.
3. yushania (BAMBUSA VULGARIS) water (or water) is heated to 70 DEG C, citric acid, glycerine, first are sequentially added
Base glucitol polyethers -20, stir evenly, and step 1 and 2 gained mixtures are then added.
4. being cooled to 40 DEG C, arginine is added and adjusts pH, discharging.
2 gained skin toner water composition efficacy assessments of embodiment --- inhibitory activity against tyrosinase is tested
With the phosphate buffer (PBS) of 0.2mol/L pH=6.8 for solvent, 2 gained toner group of embodiment is prepared respectively
Close the solution of a concentration of 0.2mg/mL of object.
The solution of the concentration 0.2mg/mL of 2 gained skin toner water composition of 0.9mL above-described embodiments is taken respectively, and 1mL L- are added
The phosphate buffer (PBS) of tyrosine (0.3mol) and 1mL pH=6.8 preheats 10 minutes in 37 DEG C of thermostatic water baths, then adds
Enter 0.1ml tyrosinases aqueous solution (1.0mg/ml, mcllvains buffer solution), is sufficiently stirred, after being reacted 15 minutes at 37 DEG C,
Measure 475nm absorbances (D1).In addition, the dense of 2 gained skin toner water composition of above-described embodiment is replaced with above-mentioned phosphate buffer
Degree is that the solution of 0.2mg/mL is similarly reacted, and measures absorbance (D2).In order to compare, it is being not added with sample solution and junket ammonia
Under conditions of sour enzyme, absorbance (D3) is measured.Inhibitory activity against tyrosinase is calculated with following formula.
Inhibitory activity against tyrosinase (%)=(D2-D1)/(D2-D3) × 100
The results are shown in Table 5：
Table 5：Inhibitory activity against tyrosinase test result table
Test result shows that the toner A (present invention) in 2 gained skin toner water composition of embodiment is to tyrosinase activity
Significantly inhibit effect；It is compared it is found that beer ferment with toner B (control), toner C (control) by toner A (present invention)
Female lysate filtrate, yushania (BAMBUSA VULGARIS) hydration used time are just notable to tyrosinase activity inhibition.
Embodiment 3：A kind of stoste of bright color
The stoste of the stoste vs. control bright colors of the bright color of the present invention
The stoste of each bright color is formulated as shown in following table 6-9：
Table 6
Table 7
Table 8
Table 9
The change rate of stoste efficacy assessments-skin brightness of 3 gained bright color of embodiment.Above-mentioned gained is highlighted into skin
The stoste of color is for testing, to test the effect of bright color.
Skin brightness is promoted, then skin toner water composition effect is better.Skin brightness variation was reflected in test period, was tested
Region L values change with time rule.
Skin brightness difference (Δ T)=using each time point L values (Tn)-after product uses L values (T0) before product
The change rate of skin brightness=(sample sets L values-sample sets L values initial value)/sample sets L value initial values
Experimental method：The stoste of 3 gained bright color of embodiment is as experimental group sample, using skin brightness tester
Skin brightness changes over time relationship before and after sample is smeared in GonioLux 4D analyses.
Smearing mode：Full face is smeared, 2 times a day, once in the morning and once at night, for 4 weeks, other skin cares are stopped using during experiment
Product.
Experimental result such as Fig. 1, the results show that the stoste A-F (present invention) of 3 gained bright color of embodiment is with good
The effect of bright color.
It is compared with stoste a, b (control) of bright color it is found that highlighting skin by stoste A, B, C (present invention) of bright color
The stoste active ingredient brewer's yeast lysate filtrate of color, yushania (BAMBUSA VULGARIS) hydration used time highlight skin
Brightness effects are just notable, have synergistic function.
By stoste D, E, F (present invention) of bright color and stoste A, B, C (present invention) comparison of bright color it is found that thick
Leaf purple bergenia herb (BERGENIA CRASSIFOLIA) root extract, broom top (SAROTHAMNUS SCOPARIUS) extract, winter
The addition of certain herbaceous plants with big flowers fruit (MALVA VERTICILLATA) extract and (G) inositol, can further promote stoste bright color of the present invention
Ability.
By stoste D, E, F (present invention) and stoste c, d, e, f (control) of bright color comparison of bright color it is found that thick
Leaf purple bergenia herb (BERGENIA CRASSIFOLIA) root extract, broom top (SAROTHAMNUS SCOPARIUS) extract, winter
Bright color effect is just notable when certain herbaceous plants with big flowers fruit (MALVA VERTICILLATA) extract and (G) inositol share, and has synergy
Effect.
It is reacted through subject, after skin toner water composition of the present invention, to skin mildly without irritation, safety is nontoxic
Side effect, to skin without any damage, 90% or more volunteer with skin after toner 4 weeks through becoming delicate glossy.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (8)
1. a kind of cosmetic composition of bright color, which is characterized in that include
(A) yushania of 30-95 wt%（BAMBUSA VULGARIS）Water,
(B) the brewer's yeast lysate filtrate of 0.1-30wt%, and
(C) optionally, common ingredient in skin protection cosmetics；
Wherein, the cosmetic combinations of total weight calculating and the bright color of the above-mentioned degree based on the composition
Object does not include the water added usually as independent component.
2. the cosmetic composition of bright color according to claim 1, which is characterized in that the yushania（BAMBUSA
VULGARIS）The content of water is 51-81wt%；The content of the brewer's yeast lysate filtrate is 2-20wt%.
3. the cosmetic composition of bright color according to claim 1 or 2, which is characterized in that the composition is free of
Chelating agent.
4. the cosmetic composition of bright color according to claim 1 or 2, which is characterized in that also include（D）0.1-
The Rhizoma Seu Herba Bergeniae of 5wt%（BERGENIA CRASSIFOLIA）The broom top of root extract, (E) 1-10wt%（SAROTHAMNUS
SCOPARIUS）The Fructus Malvae Vertillatae of extract, (F) 1-10wt%（MALVA VERTICILLATA）Extract and（G）0.1-5wt% fleshes
Alcohol.
5. a kind of method for the transdermal absorption factor increasing brewer's yeast lysate filtrate, which is characterized in that including by yushania
（BAMBUSA VULGARIS）Water is added to the makeup of the bright color comprising brewer's yeast lysate filtrate but not comprising water
In product composition.
6. according to the method described in claim 5, it is characterized in that, the composition includes the yushania of 30-95% weight
（BAMBUSA VULGARIS）The brewer's yeast lysate filtrate of water and 0.1-30% weight, the gross weight based on the composition
Amount calculates.
7. purposes of the composition as claimed in claim 1 or 2 in the cosmetic composition of the bright color not comprising water.
8. purposes according to claim 7, which is characterized in that the yushania of 30-95wt%（BAMBUSA VULGARIS）
Water, the brewer's yeast lysate filtrate of 0. 1-30wt%, 0.1-5wt% Rhizoma Seu Herba Bergeniae（BERGENIA
CRASSIFOLIA）The broom top of root extract, 1-10wt%（SAROTHAMNUS SCOPARIUS）The winter of extract, 1-10wt%
Certain herbaceous plants with big flowers fruit（MALVA VERTICILLATA）Extract and 0.1-5wt% inositols are combined, the total weight based on the composition
It calculates；The composition does not include chelating agent.
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