CN113842342B - Plant anti-dandruff antipruritic agent and preparation method and application thereof - Google Patents
Plant anti-dandruff antipruritic agent and preparation method and application thereof Download PDFInfo
- Publication number
- CN113842342B CN113842342B CN202111072434.9A CN202111072434A CN113842342B CN 113842342 B CN113842342 B CN 113842342B CN 202111072434 A CN202111072434 A CN 202111072434A CN 113842342 B CN113842342 B CN 113842342B
- Authority
- CN
- China
- Prior art keywords
- extract
- dandruff
- weight
- ethanol
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention relates to a plant anti-dandruff antipruritic agent, and a preparation method and application thereof, wherein the active ingredients of the plant anti-dandruff antipruritic agent only comprise 100-150 parts by weight of cynanchum atratum extract, 15-25 parts by weight of centella asiatica extract, 8-12 parts by weight of gentian extract and 8-12 parts by weight of loquat leaf extract. The plant anti-dandruff antipruritic has the efficient antibacterial and anti-inflammatory effects through the synergistic effect of the components, can achieve the purpose of anti-dandruff antipruritic, and has the advantages of nature, mildness, no stimulation and high safety.
Description
Technical Field
The invention relates to the field of daily chemical products, in particular to a plant anti-dandruff antipruritic agent, and a preparation method and application thereof.
Background
Dandruff is produced because scalp is constantly metabolizing, and once metabolizing is abnormal, excessive scalp cells flake off and become a coreless, inanimate stratum corneum, causing dandruff problems. A large number of researches prove that the malassezia is closely related to the generation and severity of dandruff, and the excessive proliferation of the malassezia on the scalp causes the hyperproliferation of scalp horny layer, so that horny layer cells are promoted to abnormally fall off in the form of white or gray scales, and the fallen scales are dandruff. Malassezia belongs to yeast single-cell fungi, and is on the head of a human body and depends on sucking scalp grease to survive. Healthy scalp, malassezia and scalp susceptibility, scalp grease secretion balance, natural generation and natural metabolism of dandruff, and no phenomenon of massive dandruff. Once this balance is broken, malassezia is "successful" and a large amount of metabolic waste is produced, causing scalp itching. Therefore, to solve the dandruff problem, it is necessary to control scalp grease secretion, inhibit bacteria, relieve itching, promote scalp blood circulation and improve metabolism, thereby improving scalp ecological environment, and achieving the effects of reducing dandruff generation and relieving itching.
Studies have found that about 60% of our country suffer from the problem of dandruff to varying degrees, with 15% of them having very severe symptoms. At present, the anti-dandruff shampoo accounts for more than 35 percent of the total shampoo, and 70 percent of people using the anti-dandruff shampoo have poor effect. The common anti-dandruff agents in the anti-dandruff products in the market are chemical agents such as salicylic acid, zinc pyrithione, piroctone olamine, climbazole and the like, and the anti-dandruff agents have strong degreasing effect while sterilizing and removing dandruff, and after long-term use, the anti-dandruff agents can cause atrophy of sebaceous glands in hair follicles of scalp layers and reduction of sebum secretion, so that aging of scalp cells is accelerated, dandruff is increased, dry and yellow hair is caused, and even adverse reactions such as alopecia and hair breakage are caused, so that the anti-dandruff agents are not suitable for long-term use. And with the popularity of environmental protection, low carbon, green and natural trend in recent years, products truly taking pure traditional Chinese medicine extracts as anti-dandruff antipruritic agents are popular. Therefore, there is a need to develop a purely natural, non-irritating anti-dandruff antipruritic composition that can be used in a washing and caring daily product.
Chinese patent CN108938509B discloses a composition for removing dandruff and relieving itching, its preparation method and application. The raw materials for preparing the anti-dandruff and antipruritic composition comprise the following components in percentage by mass: 3-30% of Usnea barbata extract, 5-20% of wrinkled giant hyssop extract, 2-20% of belvedere fruit extract, 1-25% of gentian extract, 30-65% of propylene glycol and 5-30% of deionized water. The active ingredients in the anti-dandruff and antipruritic compound are all from plant extracts, so that the anti-dandruff and antipruritic compound has less irritation to human bodies, and the anti-dandruff and antipruritic compound has anti-dandruff and antipruritic effects through experiments.
Chinese patent CN112656732B is shampoo for removing dandruff and relieving itching and its preparation method. The anti-dandruff itching-relieving shampoo comprises the following components in percentage by weight: 5-25% of main surface active agent, 1-5% of cosurfactant, 2-10% of mild surfactant, 0.1-5% of water-soluble grease, 0.5-4% of conditioner, 0.2-3% of sodium chloride, 0.1-3% of citric acid, 0.2-3% of sodium citrate, 1-4% of anti-dandruff and antipruritic composition and the balance of deionized water. The anti-dandruff itching-relieving shampoo is prepared from main raw materials such as a main surface active agent, a cosurfactant, a mild surfactant and the like. The effects of comprehensively and durably mildly removing dandruff and relieving itching and not damaging scalp are achieved through the synergistic compounding of the five anti-dandruff and relieving itching components. The shampoo has good cleaning and caring effects, and also has long-acting dandruff removing, oil controlling, antipruritic, scalp relieving, etc., and can reduce irritation of shampoo while ensuring dandruff removing effect.
However, while the prior art reports the use of traditional Chinese medicine components for anti-dandruff and antipruritic, the addition of other traditional Chinese medicine components, western medicine components, preservatives and/or surfactants may result in additional irritation of the composition to the skin. Therefore, the invention aims to overcome the defects of the prior art, and provides the anti-dandruff antipruritic with simple formula, no additional active ingredients, high-efficiency antibacterial and anti-inflammatory effects, natural, mild, non-irritating and high-safety effects, and the anti-dandruff antipruritic can be achieved.
Disclosure of Invention
Based on the background technology, the technical problem to be solved by the invention is to provide a plant anti-dandruff antipruritic agent, and a preparation method and application thereof. In order to achieve the aim of the invention, the following technical scheme is adopted:
the invention relates to a plant anti-dandruff antipruritic agent, which is characterized in that the active ingredients only comprise 100-150 parts by weight of cynanchum atratum extract, 15-25 parts by weight of centella asiatica extract, 8-12 parts by weight of gentian extract and 8-12 parts by weight of loquat leaf extract.
The cynanchum atratum is called white dragon whiskers, white Ma Wei, white horsetails and the like, is a vertical perennial herb plant of the genus goose down of the family Asclepiadaceae, and is used for treating deficiency and vexation, clearing heat and eliminating swelling, promoting granulation and relieving pain, and treating postpartum deficiency and vexation and vomiting, dribbling urination, nephritis, urinary tract infection, edema, bronchitis, rheumatic lumbago and skelalgia and the like.
Centella asiatica is a dried whole herb of centella asiatica belonging to the family Umbelliferae. Bitter, pungent and cold. Has effects of clearing heat and promoting diuresis, removing toxic substances and detumescence, and is commonly used for damp-heat jaundice, heatstroke diarrhea, stranguria with blood, carbuncle, swelling and sore, and traumatic injury.
The radix Gentianae is root and rhizome of gentian, gentianella acuta, gentianella trilobata and gentianella yunnanensis of gentiaceae, gentian has the effects of clearing heat, drying dampness, purging liver fire and arresting convulsion.
Loquat leaves (school name: eriobotrya japonica thunder.) are leaves of Eriobotrya japonica belonging to Rosaceae. Also called Ballon leaf and Poncirus trifoliata leaf. Has effects of clearing lung-heat, relieving cough, regulating stomach function, promoting urination, and quenching thirst. Has therapeutic effects on cough due to lung heat and phlegm, hemoptysis, epistaxis, and emesis due to stomach heat.
In a preferred embodiment of the present invention, the active ingredient comprises only 100-110 parts by weight of cynanchum atratum extract, 20-22 parts by weight of centella asiatica extract, 10-11 parts by weight of gentian extract and 10-11 parts by weight of loquat leaf extract.
In a preferred embodiment of the present invention, the preparation method of centella asiatica extract comprises: drying and pulverizing herba Centellae, adding ethanol solution with volume of 8-12 times and concentration of 70-90% for reflux extraction for 1-3 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell.
In a preferred embodiment of the present invention, the method for preparing gentian extract comprises: drying and pulverizing radix Gentianae, adding ethanol solution with volume of 8-12 times and concentration of 70-90% for reflux extraction for 1-3 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell.
In a preferred embodiment of the present invention, the preparation method of the loquat leaf extract comprises: drying and pulverizing folium Eriobotryae, adding ethanol solution with volume of 8-12 times and concentration of 70-90% for reflux extraction for 1-3 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell.
In a preferred embodiment of the present invention, the preparation method of the cynanchum atratum extract comprises: drying the cynanchum atratum at 40-50 ℃, crushing, sieving with a 30-50 mesh sieve, taking powder under the sieve, adding ethanol with the volume percentage concentration of 20-40% which is 8-12 times of the weight of the cynanchum atratum, extracting at 40-60 ℃ for 2-4 hours, filtering to obtain an alcohol extract, and recovering the ethanol under reduced pressure until no alcohol smell exists, thus obtaining the cynanchum atratum.
In another preferred embodiment of the invention, only the solvent is included in the composition in addition to the active ingredient.
In a preferred embodiment of the present invention, the solvent is a mixed solvent of water and propylene glycol, and the weight ratio of the mixed solvent is 2-3:1.
in another aspect, the invention also relates to the use of the above composition in the preparation of an anti-dandruff antipruritic.
Advantageous effects
The plant anti-dandruff antipruritic has the efficient antibacterial and anti-inflammatory effects through the synergistic effect of the components, can achieve the purpose of anti-dandruff antipruritic, and has the advantages of nature, mildness, no stimulation and high safety.
Detailed Description
In order to further understand the present invention, a technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Unless otherwise specified, all reagents involved in the examples of the present invention are commercially available products and are commercially available.
Example 1:
the preparation method of centella asiatica extract comprises the following steps: drying and pulverizing herba Centellae, adding 10 times volume of 80% ethanol solution, reflux extracting for 2 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell is present, which contains herba Centellae 20wt% or more.
The preparation method of the cynanchum atratum extract comprises the following steps: drying and crushing cynanchum atratum at 40-50 ℃, sieving with a 40-mesh sieve, taking undersize powder, adding ethanol with the volume percentage concentration of 30% which is 10 times of the weight of the cynanchum atratum for extraction, wherein the extraction temperature is 50 ℃, the extraction time is 3 hours, filtering to obtain an alcohol extract, and recovering the ethanol under reduced pressure until no alcohol smell exists, thus obtaining the cynanchum atratum extract containing more than Bai Weisu 0.3.3 weight percent.
Gentian extract and loquat leaf extract: is prepared according to the same method as that for extracting the cynanchum atratum extract.
Preparation of compositions for experimental groups:
taking 100g of cynanchum atratum extract, 20g of centella asiatica extract, 10g of gentian extract and 10g of loquat leaf extract, dispersing in a mixed solvent consisting of water and propylene glycol, wherein the amount of the mixed solvent is 300g, the composition is 200g of water plus 100g of propylene glycol, and uniformly mixing to obtain the Chinese medicinal composition.
Example 2
Taking 100g of cynanchum atratum extract, 25g of centella asiatica extract, 15g of gentian extract and 15g of loquat leaf extract, dispersing in a mixed solvent consisting of water and propylene glycol, wherein the amount of the mixed solvent is 300g, the composition is 200g of water plus 100g of propylene glycol, and uniformly mixing to obtain the Chinese medicinal composition.
Example 3
Taking 120g of cynanchum atratum extract, 20g of centella asiatica extract, 10g of gentian extract and 10g of loquat leaf extract, dispersing in a mixed solvent consisting of water and propylene glycol, wherein the amount of the mixed solvent is 300g, the composition is 200g of water plus 100g of propylene glycol, and uniformly mixing to obtain the Chinese medicinal composition.
A composition for a control group was prepared:
control group 1: the same as in example 1 above, except that centella asiatica extract was not added;
control group 2: the same as in example 1 above, except that gentian extract was not added;
control group 3: the same as in example 1 above, except that the loquat leaf extract was not added.
Pharmacodynamic experiments: test of anti-dandruff and antipruritic effects
Test object: the scalp is easy to generate itch, the dandruff is more, 120 volunteer subjects with vigorous sebum secretion are used as trial subjects, and the scalp is divided into 6 groups of 20 subjects; there were no statistical differences in the status of each group of subjects themselves prior to testing.
The using method comprises the following steps: after each group of hair is washed once every two days, 10mL of the plant anti-dandruff antipruritic agent is used for uniformly smearing the hair after washing, the hair is kept for 5 minutes, then the hair is washed clean and 30 proposals are continuously used, evaluation scores of 10 days, 20 days and 30 days after the hair is used are recorded respectively, and an average value is obtained.
Scoring criteria: the sensory evaluation method is utilized, the scalp is not itched after 10 minutes, the dandruff is obviously reduced after 10 minutes, the effect is obvious, the scalp itchiness is the worst after 1 minute, and the dandruff is easy to generate.
Table 1 subjects in each group used shampoo anti-dandruff antipruritic effect score (average value)
As is clear from the results of Table 1, the shampoo of comparative examples 1 to 3 did not contain one of the components of the plant anti-dandruff and antipruritic composition, and the anti-dandruff and antipruritic effects were generally exhibited by the subjects after use, whereas the anti-dandruff and antipruritic effects were remarkably exhibited by the subjects of examples 1 to 3 after use, and the improvement effect of example 1 was most remarkable.
Security assessment
Subject 120 were selected, 60 men and 60 women, aged 20-40 years, and sensitive skin population. Subjects were randomized into 6 groups of 20 persons each and each group of subjects was subjected to a plaque assay.
Plaque test method: selecting a qualified patch tester, coating about 0.02ml to 0.025ml of a test object into the patch tester by a closed patch test method, applying a special adhesive tape for external use on the curved side of the forearm of a subject, removing the test object after 24 hours, removing the test object for 30 minutes after the patch tester is removed, observing skin reaction after indentation disappears, and recording the result according to the skin reaction grading standard in the cosmetic hygiene Specification.
Evaluation of results: the reaction results were recorded as in Table 2 (skin adverse reaction grading criteria), and the results obtained are shown in Table 3.
TABLE 2 skin adverse reaction grading criteria
TABLE 3 safety evaluation results
The results in table 3 show: in examples 1 to 3 and control 1, the skin of each subject showed all negative responses (score scale: 0), and control 2 and control 3 showed individual suspicious responses. According to the judging standard of the human skin patch test of the cosmetic health Specification, the sample of the embodiment has no adverse reaction on human skin. This shows that the anti-dandruff antipruritic agent of the invention shows higher safety through the synergistic effect of the components, and no abnormal reaction occurs even in people using the anti-dandruff antipruritic agent on sensitive skin.
The above anti-dandruff antipruritic test and the safety test are combined to show that: the anti-dandruff and antipruritic composition has the effects of removing dandruff and relieving itching and has less irritation to human bodies.
The foregoing describes preferred embodiments of the present invention, but is not intended to limit the invention thereto. Modifications and variations to the embodiments disclosed herein may be made by those skilled in the art without departing from the scope and spirit of the invention.
Claims (3)
1. A plant anti-dandruff antipruritic agent is characterized in that the active ingredients consist of 100-150 parts by weight of cynanchum atratum extract, 15-25 parts by weight of centella asiatica extract, 8-12 parts by weight of gentian extract and 8-12 parts by weight of loquat leaf extract;
the preparation method of the cynanchum atratum extract comprises the following steps: drying and crushing cynanchum atratum at 40-50 ℃, sieving with a 30-50 mesh sieve, taking undersize powder, adding ethanol with the volume percentage concentration of 20-40% which is 8-12 times of the weight of the cynanchum atratum for extraction, wherein the extraction temperature is 40-60 ℃, the extraction time is 2-4 hours, filtering to obtain an alcohol extract, and recovering the ethanol under reduced pressure until no alcohol smell exists, thus obtaining the cynanchum atratum extract;
the preparation method of the centella asiatica extract comprises the following steps: drying and pulverizing herba Centellae, adding ethanol solution with volume of 8-12 times and concentration of 70-90% for reflux extraction for 1-3 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell;
the preparation method of the gentian extract comprises the following steps: drying and pulverizing radix Gentianae, adding ethanol solution with volume of 8-12 times and concentration of 70-90% for reflux extraction for 1-3 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell;
the preparation method of the loquat leaf extract comprises the following steps: drying and pulverizing folium Eriobotryae, adding ethanol solution with volume of 8-12 times and concentration of 70-90% for reflux extraction for 1-3 hr, filtering the extractive solution, collecting filtrate to obtain ethanol extractive solution, and recovering ethanol under reduced pressure until no ethanol smell;
the antipruritic agent further comprises a solvent, wherein the solvent consists of water and propylene glycol in a weight ratio of 2-3:1.
2. The plant anti-dandruff antipruritic agent as claimed in claim 1, wherein the active ingredient is composed of 100-110 parts by weight of cynanchum atratum extract, 20-22 parts by weight of centella asiatica extract, 10-11 parts by weight of gentian extract and 10-11 parts by weight of loquat leaf extract.
3. The use of the plant anti-dandruff and antipruritic agent as claimed in claim 1 for the preparation of an anti-dandruff and antipruritic agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111072434.9A CN113842342B (en) | 2021-09-14 | 2021-09-14 | Plant anti-dandruff antipruritic agent and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111072434.9A CN113842342B (en) | 2021-09-14 | 2021-09-14 | Plant anti-dandruff antipruritic agent and preparation method and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113842342A CN113842342A (en) | 2021-12-28 |
| CN113842342B true CN113842342B (en) | 2023-05-23 |
Family
ID=78974095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111072434.9A Active CN113842342B (en) | 2021-09-14 | 2021-09-14 | Plant anti-dandruff antipruritic agent and preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113842342B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114668695B (en) * | 2022-03-26 | 2023-01-20 | 广州市金翔化妆品有限公司 | Anti-dandruff composition, shampoo containing anti-dandruff composition and preparation method of shampoo |
| CN116850098B (en) * | 2023-02-28 | 2024-02-06 | 熠美生物科技(广州)有限公司 | Cosmetic composition of skin beautifying element and application thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105935347A (en) * | 2016-06-14 | 2016-09-14 | 马殿伟 | Entada phaseoloides containing anti-dandruff Chinese medicinal composition for cosmetics |
| CN108451828A (en) * | 2018-05-15 | 2018-08-28 | 北京爱德旺京科技发展有限公司 | It is a kind of to be used to treat hair nourishing liquid of alopecia seborrheica and preparation method thereof |
| CN109864930B (en) * | 2018-12-29 | 2021-12-28 | 上海珈凯生物科技有限公司 | Plant extract composition with scalp care effect and preparation method and application thereof |
| CN110693776A (en) * | 2019-10-23 | 2020-01-17 | 广州妮趣化妆品有限公司 | Dandruff-removing and itching-relieving scalp essence and preparation method thereof |
| CN110693777A (en) * | 2019-10-25 | 2020-01-17 | 李双峰 | Anti-hair loss and dandruff removing shampoo and preparation method thereof |
| CN113041286B (en) * | 2019-12-27 | 2022-04-15 | 上海相宜本草化妆品股份有限公司 | Plant anti-allergic agent for skin |
-
2021
- 2021-09-14 CN CN202111072434.9A patent/CN113842342B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN113842342A (en) | 2021-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113842342B (en) | Plant anti-dandruff antipruritic agent and preparation method and application thereof | |
| CN106420505B (en) | Traditional Chinese medicine plant composition, preparation method and application thereof | |
| KR100821846B1 (en) | Anti-dandruff hair care cosmetic composition | |
| KR20140071738A (en) | Cosmetic composition for alleviating dermatitis and skin irritation | |
| CN112754956A (en) | Formula and preparation method of cactus polysaccharide anti-inflammatory moisturizing mask | |
| KR101073678B1 (en) | Shampoo composition using medical herbs and manufacturing method thereof | |
| CN110840768B (en) | Artemisia argyi essence stock solution and preparation method thereof | |
| CN108836925B (en) | Anti-allergy-dry traditional Chinese medicine extract composition, preparation method thereof and application thereof in cosmetics | |
| KR101397160B1 (en) | Cosmetic compositon for skin-irritation alleviation with Inula britannica var. chinensis, Cynanchi Radix and Lysimachia foenum-graecum Hance | |
| CN109528588A (en) | Shampoo of anti-dandruff and itching-relieving and preparation method thereof | |
| CN116999361A (en) | Anti-inflammatory acne-removing mask essence, preparation method and application thereof, and anti-inflammatory acne-removing mask | |
| CN115177570B (en) | Composition with relieving and repairing effects and preparation method and application thereof | |
| CN111407707A (en) | Plant-derived skin health-care lotion and preparation method thereof | |
| CN110613663A (en) | Skin repairing composition, skin care product and preparation method thereof | |
| CN113081924B (en) | Antioxidant composition, preparation method and application | |
| CN108186440A (en) | Can antibiotic skin-care Chinese medicinal plant shower cream and its preparation method and application | |
| CN113648250A (en) | Efficient repair essence and preparation method thereof | |
| CN107898684B (en) | Plant extract composition containing fresh ginger juice and preparation method and application thereof | |
| KR20160118417A (en) | Manufacturing Method and Composion for Viper Venom Liquid Mixture | |
| KR101692910B1 (en) | Composition for relieving seborrheic dermatitis and method for manufacturing thereof | |
| KR20200109592A (en) | The composition with antioxidant and anti-inflammatory activity containing Lycium chinense leaf extract of Chengyang | |
| CN117530895B (en) | Compound plant extract with moisturizing effect and preparation and application thereof | |
| KR20150145577A (en) | Cosmetic composition for scalp and hair | |
| CN116370369B (en) | Natural plant extract composition with effects of relieving, repairing and resisting allergy and application thereof | |
| CN117243868B (en) | Camellia extract with soothing effect and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |