CN111407707A - Plant-derived skin health-care lotion and preparation method thereof - Google Patents

Plant-derived skin health-care lotion and preparation method thereof Download PDF

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CN111407707A
CN111407707A CN202010414376.2A CN202010414376A CN111407707A CN 111407707 A CN111407707 A CN 111407707A CN 202010414376 A CN202010414376 A CN 202010414376A CN 111407707 A CN111407707 A CN 111407707A
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extract
agent
parts
plant
mass
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林世施
李俊
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Guangzhou Lubiao Technology Co ltd
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Guangzhou Lubiao Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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Abstract

The invention discloses a plant-derived skin health-care lotion and a preparation method thereof, wherein the plant-derived skin health-care lotion comprises an agent A with the mass part of 76-79, an agent B with the mass part of 15.6-17.7, an agent C with the mass part of 0.55-1 and an agent D with the mass part of 2.75-3; the agent B consists of cocamide MEA, 2-sulfo-sodium methyl laurate and plant extract; heating the agent A to 80-90 ℃; adding the agent B into the agent A, and stirring for 13-20 minutes at constant temperature; then adding the agent C, and stirring for 28-32 minutes at constant temperature; cooling to below 45 ℃ and keeping the temperature constant, adding the agent D into the mixture, and stirring for 25-35 minutes; the functional plant extract can permeate into skin to regulate skin environment, thereby exerting drug effect, inhibiting skin bacteria and fungi, slowing down skin shedding speed and skin itch, promoting skin blood circulation, removing skin oil, and improving absorption of hair follicle to nutrient components.

Description

Plant-derived skin health-care lotion and preparation method thereof
Technical Field
The invention belongs to the technical field of skin care products, and particularly relates to a plant-derived skin health care lotion and a preparation method thereof.
Background
Although the common skin health-care lotion in the market at present mostly adopts nonionic surfactants, the pH is close to neutral, the lotion is mild to the skin, and the lotion is degraded quickly after being discharged into the nature. However, because most of the existing skin care lotion is prepared from purified chemical products, more chemical components always remain and are easy to damage the skin.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a preparation method of a plant-derived skin health care lotion.
The technical scheme adopted by the invention is as follows: a preparation method of a plant-derived skin health-care lotion comprises 76-79 parts by mass of an agent A, 15.6-17.7 parts by mass of an agent B, 0.55-1 part by mass of an agent C and 2.75-3 parts by mass of an agent D;
the agent B consists of cocamide MEA, 2-sulfo-sodium methyl laurate and plant extract;
the plant extract comprises radix Sophorae Flavescentis extract, cortex Dictamni Radicis extract, folium Platycladi extract, Saviae Miltiorrhizae radix extract, cortex Cinchonae extract, Coptidis rhizoma extract and rhizoma Ligustici Chuanxiong extract;
the preparation method comprises the following steps:
s1: heating the agent A to 80-90 ℃;
s2: then adding the agent B into the agent A and stirring for 13-20 minutes at constant temperature;
s3: adding the agent C into the mixture obtained in the step S2, and stirring for 28-32 minutes at constant temperature;
s4: and (4) cooling the mixture obtained in the step (S3) to below 45 ℃ and keeping the temperature constant, then adding the agent D into the mixture, and stirring the mixture for 25-35 minutes.
Further limiting, the mass part of the plant extract is 12.5-16.1.
Further, the preservative is one or a combination of more of phenoxyethanol, benzyl alcohol, benzoic acid and sorbic acid.
Further limited, the plant extract is composed of the following components in parts by weight:
the plant extract consists of the following components in parts by weight: 1-1.3 parts of sophora flavescens extract, 2-2.2 parts of cortex dictamni extract, 1.5-2.7 parts of cacumen biotae extract, 1.8-2.1 parts of salvia miltiorrhiza extract, 3-3.5 parts of cortex aristolochiae mollissimae extract, 2-2.8 parts of coptis chinensis extract and 1-1.5 parts of ligusticum wallichii extract.
Further defined, the agent A is composed of sodium laureth sulfate, sodium trideceth sulfate, di (PPG-2 myristyl polyether-10) adipate and water.
Further defined, the agent C is composed of guar hydroxypropyl trimethyl ammonium chloride, polyquaternium-10 and hydroxypropyl methyl cellulose.
Further defined, the agent D is composed of citric acid, menthol, hexamidine di (isethionic acid) salt, polyquaternium-52, coco dimethyl ammonium hydroxypropyl hydrolyzed keratin, sodium chloride, caramel color, perfume, and preservative.
Compared with the prior art, the invention has the beneficial effects that: the invention adopts the plant extract, can effectively solve the problems of skin itch and desquamation, and can regulate the skin environment through the penetration of the functional plant extract into the skin, thereby exerting the drug effect, inhibiting skin bacteria and fungi, slowing down the skin shedding speed and skin itch, promoting the blood circulation of the skin, removing skin grease and improving the absorption of hair follicles to nutrient components. Clinical experiment results show that the plant-derived skin health care lotion obviously improves skin itch and obviously reduces desquamation after being used.
The functions of each plant of the invention are as follows:
the radix sophorae flavescentis contains a large amount of alkaloids, has strong antioxidant and antiallergic properties, and can enable the skin to be in a good state;
white, fresh, bitter and cold in nature. Has the functions of dispelling wind and eliminating dampness, clearing away heat and toxic material, killing parasites and relieving itching, and can effectively kill fungi on the skin, thereby achieving the effects of relieving itching and slowing down desquamation.
Arborvitae flavor: bitter, astringent and slightly cold. Has antibacterial effect, especially has antibacterial effect against Diplococcus pneumoniae, Staphylococcus aureus, Staphylococcus albus, and Shigella sonnei, and can form protective film on the surface of affected part to repair hair follicle cells of the affected part, thereby promoting rapid healing of the affected part.
Dan Shen is slightly cold in nature and bitter in taste. Has the functions of dispelling wind and eliminating dampness, clearing away heat and toxic material, killing parasites and relieving itching, and can effectively kill fungi on the skin, thereby achieving the effects of relieving itching and slowing down desquamation.
The cinchona contains rich alkaloid, and can reduce oxygen consumption of fungi, thereby inhibiting metabolism of the fungi, finally leading to death of the fungi, and achieving the effect of relieving itching.
The coptis chinensis has the effects of clearing heat, drying dampness, purging fire and removing toxicity, has the effects of resisting bacteria, relieving heat and oxidation, and can effectively kill fungi on the skin, thereby achieving the effects of relieving itching and slowing down desquamation.
Chuan Xiong is pungent in flavor and warm in nature. Dispel cold and relieve pain, treat skin itch and desquamation externally, the Ligusticum wallichii is rich in volatile oil component, has obvious inhibition and killing effect on bacteria, and can form a protective film on the surface layer of skin to repair hair follicle cells of the affected part.
The invention also provides the plant-derived skin health-care lotion prepared by the preparation method.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the embodiments of the present invention are described in detail and completely, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
Because most of the existing skin health-care lotion is prepared from purified chemical products, more chemical components always remain and the skin is easily damaged. The plant extract is adopted in the invention, the problems of skin itch and desquamation can be effectively solved, the functional plant extract permeates into skin to condition the skin environment, so that the drug effect is exerted, skin bacteria and fungi can be inhibited, the skin desquamation speed and the skin itch can be slowed down, the blood circulation of the skin can be promoted, skin grease can be removed, and the absorption of hair follicles to nutrient components can be improved. Clinical experiment results show that the plant-derived skin health care lotion obviously improves skin itch and obviously reduces desquamation after being used.
The preparation method of each plant extract comprises the following steps:
the preparation method of the sophora flavescens extract comprises the steps of taking a proper amount of sophora flavescens root, crushing, adding water 8-12 times of the weight of the sophora flavescens, carrying out ultrasonic extraction, then filtering to obtain filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the sophora flavescens extract;
the preparation method of the dictamnus dasycarpus root bark extract comprises the steps of taking a proper amount of dictamnus dasycarpus root bark, crushing, adding water with the weight being 8-12 times that of the dictamnus dasycarpus root bark, carrying out microwave extraction, then filtering to obtain filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the dictamnus dasycarpus root bark extract;
the preparation method of the cacumen biotae extract comprises the steps of taking a proper amount of cacumen biotae, crushing, adding water with the weight 8-12 times that of the cacumen biotae, carrying out microwave extraction, then filtering to obtain a filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the cacumen biotae extract;
the preparation method of the salvia miltiorrhiza extract comprises the steps of taking a proper amount of salvia miltiorrhiza, crushing, adding water 8-12 times of the weight of the salvia miltiorrhiza, carrying out ultrasonic extraction, then filtering to obtain a filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the salvia miltiorrhiza extract;
the preparation method of the cortex cinchona extract comprises the steps of taking a proper amount of cortex cinchona, crushing, adding water with the weight 8-12 times of that of the cortex cinchona, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the cortex cinchona extract;
the preparation method of the coptis chinensis extract comprises the steps of taking a proper amount of coptis chinensis, crushing, adding water with the weight 8-12 times that of the coptis chinensis, carrying out ultrasonic extraction, then filtering to obtain filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the coptis chinensis extract;
the preparation method of the ligusticum wallichii extract comprises the steps of taking a proper amount of ligusticum wallichii, crushing, adding water with the weight 8-12 times that of the ligusticum wallichii, carrying out ultrasonic extraction, then filtering to obtain filtrate, and concentrating the filtrate to 0.1-1 g/m L to obtain the ligusticum wallichii extract.
Secondly, preparation of raw materials
Weighing 76-79 parts by mass of an agent A, 17-17.7 parts by mass of an agent B, 0.55-1 part by mass of an agent C and 2.75-3 parts by mass of an agent D;
wherein: the agent A comprises sodium laureth sulfate, sodium trideceth sulfate, di (PPG-2 myristyl polyether-10) adipate and water.
The agent B consists of cocamide MEA, 2-sulfo-sodium methyl laurate and plant extract; the mass part of the plant extract is 12.5-16.1.
The plant extract consists of the following components in parts by weight: 1-1.3 parts of sophora flavescens extract, 2-2.2 parts of cortex dictamni extract, 1.5-2.7 parts of cacumen biotae extract, 1.8-2.1 parts of salvia miltiorrhiza extract, 3-3.5 parts of cortex aristolochiae mollissimae extract, 2-2.8 parts of coptis chinensis extract and 1-1.5 parts of ligusticum wallichii extract;
the agent C consists of guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10 and hydroxypropyl methyl cellulose;
the agent D consists of citric acid, menthol, hexamidine di (hydroxyethyl sulfonate) salt, polyquaternium-52, coco dimethyl ammonium hydroxypropyl hydrolyzed keratin, sodium chloride, caramel color, essence and preservative;
the antiseptic is one or more of phenoxyethanol, benzyl alcohol, benzoic acid or sorbic acid.
Preparation of skin health care lotion from animal sources
A preparation method of a plant-derived skin health care lotion comprises the following steps:
s1: heating the agent A to 80-90 ℃;
s2: then stirring the agent B in the agent A at a constant temperature for 13-20 minutes;
s3: adding the agent C into the mixture obtained in the step S2, and stirring for 28-32 minutes at constant temperature;
s4: and (4) cooling the mixture obtained in the step (S3) to below 45 ℃ and keeping the temperature constant, then adding the agent D into the mixture, and stirring the mixture for 25-35 minutes.
Example 1
The preparation method of each plant extract comprises the following steps:
the preparation method of radix Sophorae Flavescentis extract comprises pulverizing radix Sophorae Flavescentis 30 g, adding 240 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.8g/m L to obtain radix Sophorae Flavescentis extract;
the preparation method of cortex Dictamni Radicis extract comprises pulverizing 50 g cortex Dictamni Radicis, adding 500 g water, microwave extracting for 30 min with power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 0.7g/m L to obtain cortex Dictamni extract;
the folium Platycladi extract is prepared by pulverizing 40 g folium Platycladi, adding 480 g water, microwave extracting for 30 min at power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain folium Platycladi extract;
the preparation method of Saviae Miltiorrhizae radix extract comprises pulverizing 50 g Saviae Miltiorrhizae radix, adding 450 g water, performing ultrasonic extraction for 40 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.8g/m L to obtain Saviae Miltiorrhizae radix extract;
the cortex Cinchonae extract is prepared by pulverizing cortex Cinchonae 80 g, adding 640 g water, microwave extracting for 50 min at power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain cortex Cinchonae extract;
the Coptidis rhizoma extract is prepared by pulverizing Coptidis rhizoma 30 g, adding 270 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.9g/m L to obtain Coptidis rhizoma extract;
the rhizoma Ligustici Chuanxiong extract is prepared by pulverizing rhizoma Ligustici Chuanxiong 30 g, adding water 240 g, ultrasonic extracting for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain rhizoma Ligustici Chuanxiong extract.
Secondly, preparation of raw materials
Weighing 76 parts by mass of an agent A, 17 parts by mass of an agent B, 0.55 part by mass of an agent C and 2.75 parts by mass of an agent D;
wherein: the agent A comprises 13 parts by mass of sodium laureth sulfate, 1.5 parts by mass of sodium trideceth sulfate, 0.5 parts by mass of bis (PPG-2 myristyl polyether-10) adipate and 61 parts by mass of water.
The agent B consists of 0.5 mass part of cocamide MEA, 1.5 mass part of sodium methyl 2-sulfolaurate and 15 mass parts of plant extract; the plant extract comprises 1.1 parts by mass of radix sophorae flavescentis extract, 2.1 parts by mass of cortex dictamni extract, 2.5 parts by mass of cacumen biotae extract, 2 parts by mass of radix salviae miltiorrhizae extract, 3.3 parts by mass of cortex aristolochiae extract, 2.6 parts by mass of rhizoma coptidis extract and 1.4 parts by mass of rhizoma ligustici wallichii extract;
the agent C consists of 0.3 part by mass of guar gum hydroxypropyl trimethyl ammonium chloride, 0.05 part by mass of polyquaternium-10 and 0.2 part by mass of hydroxypropyl methyl cellulose;
the agent D consists of 0.2 mass part of citric acid, 0.2 mass part of menthol, 0.05 mass part of hexamidine di (hydroxyethyl sulfonate) salt, 0.8 mass part of polyquaternium-52, 0.3 mass part of coco dimethyl ammonium hydroxypropyl hydrolyzed keratin, 0.2 mass part of sodium chloride, 0.2 mass part of caramel color, 0.2 mass part of essence and 0.6 mass part of preservative; the antiseptic is a combination of phenoxyethanol, benzyl alcohol, benzoic acid and sorbic acid.
Preparation of skin health care lotion from animal sources
A preparation method of a plant-derived skin health care lotion comprises the following steps:
s1: putting the agent A into an emulsifying pot, stirring and heating to 80 ℃;
s2: after the agent A is dispersed and dissolved uniformly, adding the agent B into the agent A and stirring for 13 minutes at the constant temperature of 80 ℃;
s3: adding the agent C into the mixture obtained in the step S2, and stirring for 28 minutes at the constant temperature of 80 ℃;
s4: and (4) cooling the mixture obtained in the step (S3) to 40 ℃ and maintaining the temperature, then adding the agent D into the mixture, and stirring the mixture for 25 minutes to obtain the plant-derived skin health care lotion.
Example 2
The preparation method of each plant extract comprises the following steps:
the preparation method of radix Sophorae Flavescentis extract comprises pulverizing radix Sophorae Flavescentis 30 g, adding 270 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain radix Sophorae Flavescentis extract;
the preparation method of cortex Dictamni Radicis extract comprises pulverizing 50 g cortex Dictamni Radicis, adding 400 g water, microwave extracting for 30 min with power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain cortex Dictamni extract;
the folium Platycladi extract is prepared by collecting folium Platycladi 40 g, pulverizing, adding 320 g water, microwave extracting for 30 min with power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain folium Platycladi extract;
the preparation method of Saviae Miltiorrhizae radix extract comprises pulverizing 50 g Saviae Miltiorrhizae radix, adding 400 g water, performing ultrasonic extraction for 40 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain Saviae Miltiorrhizae radix extract;
the cortex Cinchonae extract is prepared by pulverizing cortex Cinchonae 80 g, adding 720 g water, microwave extracting for 50 min at power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain cortex Cinchonae extract;
the Coptidis rhizoma extract is prepared by pulverizing Coptidis rhizoma 30 g, adding 240 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain Coptidis rhizoma extract;
the preparation method of rhizoma Ligustici Chuanxiong extract comprises pulverizing rhizoma Ligustici Chuanxiong 30 g, adding water 270 g, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 0.1g/m L to obtain rhizoma Ligustici Chuanxiong extract.
Secondly, preparation of raw materials
Weighing 77.8 parts by mass of an agent A, 15.6 parts by mass of an agent B, 0.8 part by mass of an agent C and 2.95 parts by mass of an agent D;
wherein: the agent A comprises 15 parts by mass of sodium laureth sulfate, 1.5 parts by mass of sodium trideceth sulfate, 0.3 parts by mass of bis (PPG-2 myristyl polyether-10) adipate and 61 parts by mass of water.
The agent B consists of 1.5 parts by mass of cocamide MEA, 1.6 parts by mass of sodium methyl 2-sulfolaurate and 12.5 parts by mass of plant extract; the plant extract comprises 1 part by mass of radix sophorae flavescentis extract, 2 parts by mass of cortex dictamni extract, 1.5 parts by mass of cacumen biotae extract, 1.8 parts by mass of salvia miltiorrhiza extract, 3 parts by mass of cortex allii utilis extract, 2.2 parts by mass of coptis chinensis extract and 1 part by mass of ligusticum wallichii extract;
the agent C consists of 0.4 part by mass of guar gum hydroxypropyl trimethyl ammonium chloride, 0.15 part by mass of polyquaternium-10 and 0.25 part by mass of hydroxypropyl methyl cellulose;
the agent D consists of 0.2 mass part of citric acid, 0.2 mass part of menthol, 0.17 mass part of hexamidine di (hydroxyethyl sulfonate) salt, 1.1 mass part of polyquaternium-52, 0.3 mass part of coco dimethyl ammonium hydroxypropyl hydrolyzed keratin, 0.3 mass part of sodium chloride, 0.2 mass part of caramel color, 0.2 mass part of essence and 0.6 mass part of preservative; the antiseptic is phenoxyethanol.
Preparation of skin health care lotion from animal sources
A preparation method of a plant-derived skin health care lotion comprises the following steps:
s1: putting the agent A into an emulsifying pot, stirring and heating to 85 ℃;
s2: after the agent A is dispersed and dissolved uniformly, adding the agent B into the agent A and stirring for 17 minutes at the constant temperature of 85 ℃;
s3: adding an agent C to the mixture obtained in the step S2, and stirring for 30 minutes at a constant temperature of 85 ℃;
s4: and (4) cooling the mixture obtained in the step (S3) to 38 ℃ and maintaining the temperature, then adding the agent D into the mixture, and stirring the mixture for 32 minutes to obtain the plant-derived skin health care lotion.
Example 3
The preparation method of each plant extract comprises the following steps:
the preparation method of radix Sophorae Flavescentis extract comprises pulverizing radix Sophorae Flavescentis 30 g, adding 360 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain radix Sophorae Flavescentis extract;
the preparation method of cortex Dictamni Radicis extract comprises pulverizing 50 g cortex Dictamni Radicis, adding 600 g water, microwave extracting for 30 min with power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain cortex Dictamni extract;
the folium Platycladi extract is prepared by pulverizing 40 g folium Platycladi, adding 360 g water, microwave extracting for 30 min at power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain folium Platycladi extract;
the preparation method of Saviae Miltiorrhizae radix extract comprises pulverizing 50 g Saviae Miltiorrhizae radix, adding 600 g water, performing ultrasonic extraction for 40 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain Saviae Miltiorrhizae radix extract;
the cortex Cinchonae extract is prepared by pulverizing cortex Cinchonae 80 g, adding 960 g water, microwave extracting for 50 min at power of 150W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain cortex Cinchonae extract;
the Coptidis rhizoma extract is prepared by pulverizing Coptidis rhizoma 30 g, adding 360 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain Coptidis rhizoma extract;
the rhizoma Ligustici Chuanxiong extract is prepared by pulverizing rhizoma Ligustici Chuanxiong 30 g, adding 360 g water, performing ultrasonic extraction for 20 min with power of 70W, filtering to obtain filtrate, and concentrating the filtrate to 1g/m L to obtain rhizoma Ligustici Chuanxiong extract.
Secondly, preparation of raw materials
Weighing 79 parts of an agent A, 17.7 parts of an agent B, 1 part of an agent C and 3 parts of an agent D;
wherein: the agent A comprises 16 parts by mass of sodium laureth sulfate, 1.5 parts by mass of sodium trideceth sulfate, 0.5 parts by mass of bis (PPG-2 myristyl polyether-10) adipate and 61 parts by mass of water.
The agent B consists of 0.9 mass part of cocamide MEA, 0.8 mass part of sodium methyl 2-sulfolaurate and 16.1 mass parts of plant extract; the plant extract comprises 1.3 parts by mass of radix sophorae flavescentis extract, 2.2 parts by mass of cortex dictamni extract, 2.7 parts by mass of cacumen biotae extract, 2.1 parts by mass of salvia miltiorrhiza extract, 3.5 parts by mass of cortex allii utilis extract, 2.8 parts by mass of coptis chinensis extract and 1.5 parts by mass of ligusticum wallichii extract;
the agent C consists of 0.4 part by mass of guar gum hydroxypropyl trimethyl ammonium chloride, 0.15 part by mass of polyquaternium-10 and 0.25 part by mass of hydroxypropyl methyl cellulose;
the agent D consists of 0.2 mass part of citric acid, 0.2 mass part of menthol, 0.17 mass part of hexamidine di (hydroxyethyl sulfonate) salt, 1.1 mass part of polyquaternium-52, 0.3 mass part of coco dimethyl ammonium hydroxypropyl hydrolyzed keratin, 0.3 mass part of sodium chloride, 0.2 mass part of caramel color, 0.2 mass part of essence and 0.6 mass part of preservative; the antiseptic is phenoxyethanol.
Preparation of skin health care lotion from animal sources
A preparation method of a plant-derived skin health care lotion comprises the following steps:
s1: putting the agent A into an emulsifying pot, stirring and heating to 85 ℃;
s2: after the agent A is dispersed and dissolved uniformly, adding the agent B into the agent A and stirring for 17 minutes at the constant temperature of 85 ℃;
s3: adding an agent C to the mixture obtained in the step S2, and stirring for 30 minutes at a constant temperature of 85 ℃;
s4: and (4) cooling the mixture obtained in the step (S3) to 38 ℃ and maintaining the temperature, then adding the agent D into the mixture, and stirring the mixture for 32 minutes to obtain the plant-derived skin health care lotion.
Clinical trial
Collecting volunteer patients with skin pruritus, dry skin and desquamation symptoms between 12-45 years old, and taking patients between 12-25 years old as a first group; patients of 26-35 years old are the second group, and patients of 36-45 years old are the third group;
a first group of patients, who were 100 persons in total, were divided into 3 groups, and 3 groups used the plant-derived skin care lotion prepared in example 1, example 2, and example 3, respectively, every 3 days for 3 months, and the skin was examined and recorded as shown in table 1;
a second group of patients, who were 200 persons in total, were divided into 3 groups, and 3 groups used the plant-derived skin care lotion prepared in example 1, example 2 and example 3, respectively, every 4 days for 2 months, and the skin was examined and recorded as shown in table 1;
a third group of 120 patients, divided into 3 groups, and 3 groups used the plant-derived skin care lotion prepared in example 1, example 2 and example 3 every 5 days for 3 months, and the skin was examined and recorded as shown in table 1;
Figure BDA0002494400130000131
Figure BDA0002494400130000141
the invention is not limited to the above alternative embodiments, and any other various forms of products can be obtained by anyone in the light of the present invention, but any changes in shape or structure thereof, which fall within the scope of the present invention as defined in the claims, fall within the scope of the present invention.

Claims (8)

1. A preparation method of a plant-derived skin health-care lotion is characterized by comprising 76-79 parts by mass of an agent A, 15.6-17.7 parts by mass of an agent B, 0.55-1 part by mass of an agent C and 2.75-3 parts by mass of an agent D;
the agent B consists of cocamide MEA, 2-sulfo-sodium methyl laurate and plant extract;
the plant extract comprises radix Sophorae Flavescentis extract, cortex Dictamni Radicis extract, folium Platycladi extract, Saviae Miltiorrhizae radix extract, cortex Cinchonae extract, Coptidis rhizoma extract and rhizoma Ligustici Chuanxiong extract;
the preparation method comprises the following steps:
s1: heating the agent A to 80-90 ℃;
s2: then adding the agent B into the agent A and stirring for 13-20 minutes at constant temperature;
s3: adding the agent C into the mixture obtained in the step S2, and stirring for 28-32 minutes at constant temperature;
s4: and (4) cooling the mixture obtained in the step (S3) to below 45 ℃ and keeping the temperature constant, then adding the agent D into the mixture, and stirring the mixture for 25-35 minutes.
2. The method for preparing a plant-derived skin care lotion according to claim 1, wherein the plant extract is present in an amount of 12.5 to 16.1 parts by mass.
3. The preparation method of the plant-derived skin care lotion according to claim 1 or 2, wherein the plant extract is composed of the following components in parts by mass:
the plant extract consists of the following components in parts by weight: 1-1.3 parts of sophora flavescens extract, 2-2.2 parts of cortex dictamni extract, 1.5-2.7 parts of cacumen biotae extract, 1.8-2.1 parts of salvia miltiorrhiza extract, 3-3.5 parts of cortex aristolochiae mollissimae extract, 2-2.8 parts of coptis chinensis extract and 1-1.5 parts of ligusticum wallichii extract.
4. The method of preparing a skin care lotion derived from a plant according to claim 3, wherein said agent A comprises sodium laureth sulfate, sodium trideceth sulfate, di (PPG-2 myristyl polyether-10) adipate, and water.
5. The method of preparing a plant-derived skin-care lotion according to claim 3, wherein the agent C comprises guar hydroxypropyltrimonium chloride, polyquaternium-10, and hydroxypropylmethylcellulose.
6. The method of preparing a botanical skin wellness lotion according to claim 3 wherein said D agent is comprised of citric acid, menthol, hexamidine di (isethionate) salt, polyquaternium-52, coco dimethyl ammonium hydroxypropyl hydrolyzed keratin, sodium chloride, caramel color, perfume, and preservative.
7. The method for preparing a plant-derived skin care lotion according to claim 6, wherein the preservative is a composition of one or more of phenoxyethanol, benzyl alcohol, benzoic acid or sorbic acid.
8. A plant-derived skin care lotion prepared by the preparation method according to any one of claims 1 to 7.
CN202010414376.2A 2020-05-15 2020-05-15 Plant-derived skin health-care lotion and preparation method thereof Pending CN111407707A (en)

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CN113662896A (en) * 2021-09-28 2021-11-19 广州路标科技有限公司 Plant-derived skin-care whole-body lotion and preparation method and application thereof
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