CN111346173A - Traditional Chinese medicine composition, traditional Chinese medicine essential oil, traditional Chinese medicine skin care product and preparation method - Google Patents

Traditional Chinese medicine composition, traditional Chinese medicine essential oil, traditional Chinese medicine skin care product and preparation method Download PDF

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CN111346173A
CN111346173A CN202010105437.7A CN202010105437A CN111346173A CN 111346173 A CN111346173 A CN 111346173A CN 202010105437 A CN202010105437 A CN 202010105437A CN 111346173 A CN111346173 A CN 111346173A
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chinese medicine
traditional chinese
essential oil
skin
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钱亚秋
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/80Scrophulariaceae (Figwort family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
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    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/9783Angiosperms [Magnoliophyta]
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    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
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Abstract

The invention provides a traditional Chinese medicine composition which comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of bletilla striata, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of pharbitis seed, 5-15 parts of Japanese ampelopsis, 5-15 parts of dittany bark, 5-20 parts of white muscardine silkworm, 5-15 parts of white poria, 5-15 parts of rhizoma typhonii, 5-10 parts of tribulus terrestris, 15-25 parts of safflower, 15-25 parts of Chinese waxgourd seed, 20-35 parts of peach kernel, 20-35 parts of radix rehmanniae, 15-25 parts of rhodiola rosea, 20-35 parts of chamomile, 20-35 parts of rose, 20-35 parts of peony flower, 20-35 parts of peach blossom, 20-35 parts of lavender and 20-70 parts of ginseng. The product is suitable for people with lusterless complexion or blackish patch due to retention of water-damp in the skin, and has effects of eliminating macula, healing sore, promoting blood circulation, eliminating dampness, dispelling pathogenic wind, nourishing skin, whitening skin, resolving macula, and treating soup fire burn, sore, and rhagadia manus et pedis. The invention also provides traditional Chinese medicine essential oil containing the traditional Chinese medicine components, a traditional Chinese medicine skin care product and a preparation method.

Description

Traditional Chinese medicine composition, traditional Chinese medicine essential oil, traditional Chinese medicine skin care product and preparation method
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition, traditional Chinese medicine essential oil, a traditional Chinese medicine skin care product and a preparation method.
Background
Aging (Aging), also known as Aging, is a necessary stage in the process of any biological activity, and is a gradual and genetic factor-influenced irreversible decline process of complex morphological structure and physiological function of the whole body along with the growth and maturity of organisms. The skin is the largest organ of the human body, plays roles in protecting, feeling, regulating body temperature, secreting, excreting, immunizing and the like, and gradually ages like other organs of the human body with the aging, so that the function is weakened and lost, and various pathological changes are generated.
Aged skin, characterized apparently by skin laxity and appearance of wrinkles, skin roughness at exposed parts of the body, and wrinkles deepening and thickening; abnormal epidermal structure, pigmentation and senile plaque; the skin elasticity is not changed and becomes loose; vasodilatation, epidermal keratosis, etc. In aging skin, epidermal cell renewal is slowed, barrier function is diminished, keratinocyte viability is reduced, and repair ability after epidermal injury is diminished, wherein the diminishment of barrier function results in skin dryness, desquamation, wrinkles, and the like. The number of fibroblasts in the dermis layer of aging skin gradually decreases, the ability to synthesize collagen and elastin decreases, the ratio of type I collagen to type III collagen decreases, collagen fibers become thick, and abnormal cross-linking occurs. Meanwhile, the Langerhans cells are reduced, the immunity is reduced, and the infectious diseases are easy to be caused. In addition, as the number of melanocytes in aging skin decreases significantly, exposure to sunlight is vulnerable to injury, resulting in a significant increase in lipofuscin, presenting with age spots and other local pigmentary changes. In addition to the epidermis and dermis, the skin appendages also undergo significant changes during skin aging: the aged skin has atrophy of sebaceous glands and sweat glands, reduced secretion, reduced sweating reaction, insufficient emulsion on the skin surface, and weakened hydration ability of stratum corneum, so that the skin is rough and cracked.
Chloasma is called as 'blackish black spots', 'liver spots', 'face dust' in traditional Chinese medicine. The pathogenesis of this disease is discussed in the classic literature of traditional Chinese medicine. The theory of the sources of the diseases: the blackish complexion, phlegm-fluid retention in the zang-fu organs or wind-evil in the skin can cause disharmony between qi and blood and produce blackish complexion. The twelve meridians and blood of the five zang-organs and six fu-organs all go on the face, and nourish the exterior and interior due to the movement of fu-blood. The skin becomes black when people are exposed to phlegm and fluid, or the skin striae is affected by wind to cause disharmony of blood and qi, or astringent or turbid. The theory of the sources of the diseases: the blackish complexion, phlegm-fluid retention in the zang-fu organs or wind-evil in the skin can cause disharmony between qi and blood and produce blackish complexion. The twelve meridians and blood of the five zang-organs and six fu-organs all go on the face, and nourish the exterior and interior due to the movement of fu-blood. The skin becomes black when people are exposed to phlegm and fluid, or the skin striae is affected by wind to cause disharmony of blood and qi, or astringent or turbid. 'Yi Zong jin Jian' is characterized by: it is usually caused by depression, blood deficiency, dryness and stagnation of fire on the face, and is common in many women. The term "big surgical adults" is: the dark and dark spots usually appear on the surface of women and are caused by the blood deficiency and the fire dryness. "surgical orthodox" is recorded: for a deep-colored patch, the deficiency of water cannot control fire and the blood cannot bloom the meat, so the fire is dry and black, and the color is dark. The traditional Chinese medicine considers that the internal cause of the disease is closely related to the abnormality of the three organs of liver, spleen and kidney and the circulation of qi and blood, so that internal treatment mostly treats the viscera from liver, spleen and kidney, and qi and blood mostly regulate qi, nourish blood and activate blood; the external cause of this disease is the malnutrition of the meridians due to the wind-striae, or the unsmooth or turbid nature of the skin, or the weak and lusterless blood with the dry fire, which is caused by the blood deficiency or the wind-evil or the unsmooth circulation of qi and blood. Therefore, external treatment should be done in view of tonifying blood, promoting blood circulation and expelling wind.
In traditional Chinese medicine, all sores are caused by wind-heat damp-toxin, so that the traditional Chinese medicine is used for treating sore swelling and nodes, dispelling wind and dispersing nodes, clearing heat and removing toxicity, and eliminating swelling and promoting granulation. The sores, burns, scalds and incised wounds leave scars in the natural healing process, and particularly, the scars are easy to grow for some patients with scar constitutions.
Therefore, there is a great need in the art for a Chinese medicinal composition, a Chinese medicinal essential oil, a Chinese medicinal skin care product and a preparation method thereof, which are capable of delaying skin aging, promoting blood circulation to remove blood stasis, dispelling wind and resolving masses, and promoting wound and scar healing.
The invention is provided in view of the above.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition, traditional Chinese medicine essential oil, a traditional Chinese medicine skin care product and a preparation method thereof, so as to solve at least one technical problem.
Specifically, the invention provides a traditional Chinese medicine composition which comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of bletilla striata, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of pharbitis seed, 5-15 parts of Japanese ampelopsis, 5-15 parts of dittany bark, 5-20 parts of white muscardine silkworm, 5-15 parts of white poria, 5-15 parts of rhizoma typhonii, 5-10 parts of tribulus terrestris, 15-25 parts of safflower, 15-25 parts of Chinese waxgourd seed, 20-35 parts of peach kernel, 20-35 parts of radix rehmanniae, 15-25 parts of rhodiola rosea, 20-35 parts of chamomile, 20-35 parts of rose, 20-35 parts of peony flower, 20-35 parts of peach blossom, 20-35 parts of lavender and 20-70 parts of ginseng.
By adopting the scheme, the safflower, the peach blossom, the peony flower and the rose flower have the effects of activating blood, and the peach kernel, the rhodiola rosea, the bighead atractylodes rhizome, the spleen and the qi, the rose flower and the ginseng have the effects of activating blood and dissolving stasis, invigorating primordial qi, and promoting blood circulation by qi circulation, so that the effects of activating blood and dissolving stasis are achieved, the blood circulation on the surface of skin is promoted, and the metabolism is accelerated; radix Angelicae Dahuricae, Bombyx Batryticatus, rhizoma Typhonii, fructus Atriplicis Sibiricae, radix Ampelopsis, and Lavender for dispelling pathogenic wind and resolving hard mass, and can be used for eliminating skin ulcer and scar; the traditional Chinese medicine composition is suitable for people with poor complexion or dark raw patch due to internal water-damp stagnation, can eliminate ecchymoses and heal sores on the surface of skin, activate blood, dry dampness and expel wind together, nourish skin, whiten and remove freckles, and can treat burns caused by soup fire of hands and feet, sores and rhagades; the dried rehmannia root and the ginseng can promote the production of body fluid, moisten the skin and prevent excessive dampness; flos Matricariae Chamomillae, Lavender, flos Rosae Rugosae, Bombyx Batryticatus relieve pain, and rhizoma Bletillae and radix Rhodiolae stop bleeding, and can be used for relieving pain and stopping bleeding of wound such as scald and incised wound due to hot water and fire; however, Tribulus terrestris, rhizoma Typhonii and semen Pharbitidis are toxic, and Ampelopsis japonica, cortex Dictamni Radicis and Lavender are used for clearing away heat and toxic materials, and can remove damp-heat and restrict toxicity.
Preferably, the traditional Chinese medicine composition can be prepared into a solution, a tincture, a suspension, an emulsion or a paste by extracting effective components with a solvent, or can be completely ground into powder and blended into a paste when in use.
Preferably, the traditional Chinese medicine composition comprises the following components in parts by weight: 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of bighead atractylodes rhizome, 10 parts of pharbitis seed, 10 parts of ampelopsis japonica, 10 parts of cortex dictamni, 10 parts of white muscardine silkworm, 10 parts of white poria, 10 parts of rhizoma typhonii, 10 parts of tribulus terrestris, 20 parts of safflower, 20 parts of Chinese waxgourd seed, 30 parts of peach kernel, 30 parts of radix rehmanniae recen, 20 parts of rhodiola rosea, 30 parts of chamomile, 30 parts of rose, 30 parts of peony, 30 parts of peach blossom, 30 parts of lavender and 50 parts of ginseng.
By adopting the scheme, the curative effects of promoting blood circulation to remove blood stasis, resisting aging and the like are more obvious.
The invention also provides traditional Chinese medicine essential oil which comprises the following components:
the proportion of the traditional Chinese medicine composition to the olive oil is 1: (2-3).
By adopting the scheme, the olive oil is used as a solvent to dissolve effective components, and the olive oil contains vitamin E and antioxidant components, so that the olive oil can protect the skin, particularly prevent the skin from being damaged and aged, enable the skin to have luster, nourish eyelashes and make the eyelashes dense and long. In addition, modern researches show that rhodiola rosea resists oxidation, chamomile repairs sensitive skin, lavender can promote cell regeneration and accelerate wound healing, the traditional Chinese medicine essential oil can promote blood circulation to remove blood stasis, remove sores and promote tissue regeneration, relieve pain and stop bleeding, various scars on the surface of the skin can be effectively reduced after long-term use, the skin can be smooth and fine, and the beauty effect is good.
The invention also provides a preparation method of the traditional Chinese medicine essential oil, which comprises the following steps:
pulverizing the Chinese medicinal materials, sieving with 200 mesh sieve, mixing with oleum Olivarum, and soaking for 1-3 months;
boiling the mixture in water for 10-14 h;
continuing soaking for 1-2 months.
By adopting the scheme, the process is mild, the active ingredients are not damaged, and the components are fully leached and reacted to achieve the balance of the components.
The invention also provides a preparation method of the traditional Chinese medicine essential oil, which comprises the following steps:
putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria and safflower into a gauze bag, putting the gauze bag into olive oil with the weight of 1-2 times of the total weight of the medicaments, performing ultrasonic extraction, and extracting for 8 hours;
decocting fructus Atriplicis Sibiricae, rhizoma Typhonii, and semen Pharbitidis with 5-10 times of water for 1 hr, filtering, mixing the filtrate with the rest amount of oleum Olivarum, stirring for 0.5-1 hr, standing, layering, and collecting organic phase;
pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve;
mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus, and making into Chinese medicinal essential oil.
By adopting the scheme, the extraction efficiency is accelerated by utilizing ultrasonic extraction; decocting fructus Atriplicis Sibiricae, rhizoma Typhonii, and semen Pharbitidis in water for 1 hr to effectively remove toxic components, wherein rhizoma Typhonii can effectively remove aluminum ions generated by processing with Alumen, extract effective components such as fatty acid, amino acids, steroid compounds, and saponin, destroy enzymes, and reduce toxicity; the silkworm larva can effectively preserve amino acid and fatty acid, and also has active ingredients such as oxalic amine, protease, chitinase and lipase, and the like, can digest cutin, decompose pigment, prevent scars, remove acnes and treat ecchymosis.
Preferably, the temperature is maintained at 40-60 ℃ during the ultrasonic extraction.
By adopting the scheme, the extraction efficiency is improved.
Further, before the medicine is put into a gauze bag, the chamomile, the rose, the peony and the peach flower are subjected to pedicle removal, the lavender is subjected to impurity removal, the peach kernel and the Chinese waxgourd seed are crushed, and the radix rehmanniae recen, the rhodiola rosea and the ginseng are crushed into small pieces.
By adopting the scheme, the medicine is crushed into small blocks, and the small blocks are blocks with the diameter smaller than 1cm, so that the extraction efficiency is improved, and the influence of impurities is removed.
Further, the filtrate is mixed with the rest part of olive oil and the pH value of the water phase is adjusted to 6.2-6.7 by hydrochloric acid or sulfuric acid during stirring.
By adopting the scheme, the pH is adjusted to enable the organic acid to be dissociated and enter the olive oil, so that the extraction rate of the effective components is improved, and the irritation to the skin is reduced.
Further, the traditional Chinese medicine essential oil also comprises 20-30 parts of holy basil by weight.
By adopting the scheme, the holy basil incense is fragrant and avoids dirtiness, is mainly used for improving or shielding bad smell, has pleasant smell, and is beneficial to being used as a skin care product.
The invention also provides a traditional Chinese medicine skin care product which comprises the following components in percentage by volume:
10-20 parts of lemon vinegar solution, 1-3 parts of the traditional Chinese medicine essential oil and 5-10 parts of honey.
By adopting the scheme, the lemon vinegar solution is used for removing cutin and promoting the permeation of effective components, the water-soluble components in the stiff silkworm powder in the traditional Chinese medicine essential oil can permeate into the skin, the traditional Chinese medicine essential oil has the effect, and the honey is used for blending the lemon vinegar solution and the traditional Chinese medicine essential oil to ensure that the skin achieves water-oil balance.
Further, the preparation method of the lemon vinegar solution comprises the following steps:
slicing 1-3 parts of lemon by weight, and fermenting in 1-5 parts of rice vinegar for 3-6 days;
filtering to obtain fermentation liquor;
mixing the fermentation liquor and water according to the volume ratio of 1: (10-20) mixing.
By adopting the scheme, the concentration of acetic acid in the rice vinegar is 3% -9%, and the contained acetobacter and yeast ferment the organic acid in the lemon, so that the irritation to the skin is reduced.
Further, sodium bicarbonate is added into the lemon vinegar solution, and the pH is adjusted to 6.4-6.8.
By adopting the scheme, the skin is prevented from being injured by too high acidity, sodium bicarbonate reacts with acetic acid to form sodium acetate, and the sodium acetate and the acetic acid form a buffer system, so that the skin is prevented from being injured by too low pH when the sodium bicarbonate is mixed with honey.
In conclusion, the invention has the following beneficial effects:
1. the safflower, the peach blossom, the peony and the rose flower have the effects of activating blood, the peach kernel is added for activating blood and dissolving stasis, the rhodiola rosea is added for activating blood and replenishing qi, the bighead atractylodes rhizome is added for invigorating spleen and replenishing qi, the rose flower is used for promoting qi circulation, the ginseng is used for greatly invigorating primordial qi, and qi circulation is performed, so that blood circulation is performed, the effects of activating blood and dissolving stasis are jointly played, blood circulation on the surface of; radix Angelicae Dahuricae, Bombyx Batryticatus, rhizoma Typhonii, fructus Atriplicis Sibiricae, radix Ampelopsis, and Lavender for dispelling pathogenic wind and resolving hard mass, and can be used for eliminating skin ulcer and scar; the traditional Chinese medicine composition is suitable for people with poor complexion or dark raw patch due to internal water-damp stagnation, can eliminate ecchymoses and heal sores on the surface of skin, activate blood, dry dampness and expel wind together, nourish skin, whiten and remove freckles, and can treat burns caused by soup fire of hands and feet, sores and rhagades of hands and feet.
2. The dried rehmannia root and the ginseng can promote the production of body fluid, moisten the skin and prevent excessive dampness;
3. flos Matricariae Chamomillae, Lavender, flos Rosae Rugosae, Bombyx Batryticatus relieve pain, and rhizoma Bletillae and radix Rhodiolae stop bleeding, and can be used for relieving pain and stopping bleeding of wound such as scald and incised wound due to hot water and fire;
4. tribulus terrestris, rhizoma Typhonii and semen Pharbitidis are toxic, and Ampelopsis japonica, cortex Dictamni and Lavender are used for clearing away heat and toxic materials to restrict heat and toxicity.
5. The olive oil is used as a solvent to dissolve effective components, and contains vitamin E and antioxidant components, so that the olive oil can protect skin, especially prevent skin damage and aging, make skin glossy, nourish eyelashes and make the eyelashes dense and long;
6. the holy basil fragrance is fragrant and avoids dirtiness, is mainly used for improving or shielding bad smell, has pleasant smell and is beneficial to being used as a skin care product;
7. ultrasonic extraction is utilized to accelerate extraction efficiency;
8. decocting fructus Atriplicis Sibiricae, rhizoma Typhonii, and semen Pharbitidis in water for 1 hr to effectively remove toxic components, wherein rhizoma Typhonii can effectively remove aluminum ions generated by processing with Alumen, extract effective components such as fatty acid, amino acids, steroid compounds, and saponin, destroy enzymes, and reduce toxicity; the white muscardine silkworm not only can effectively preserve amino acid and fatty acid, but also has active ingredients such as oxalic amine, protease, chitinase and lipase, and the like, can digest cutin, decompose pigment, prevent scars, remove acnes and treat ecchymosis;
9. the concentration of acetic acid in the rice vinegar is 3% -9%, and the contained acetobacter and yeast ferment the organic acid in the lemon to reduce the irritation to the skin;
10. the sodium bicarbonate reacts with acetic acid to form sodium acetate, and forms a buffer system with the acetic acid to prevent the pH from being too low to hurt the skin when the sodium bicarbonate is mixed with the honey.
Detailed Description
Exemplary embodiments will be described in detail herein. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present invention. Rather, they are merely examples of apparatus and methods consistent with certain aspects of the invention, as detailed in the appended claims.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in this specification and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.
The nature, flavor, meridian tropism and function of the traditional Chinese medicines are mainly as follows:
radix angelicae: pungent and warm. It enters stomach, large intestine and lung meridians. Relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, stopping leukorrhagia, relieving swelling, and expelling pus. Can be used for treating common cold, headache, supercilium pain, nasal obstruction, nasal discharge, allergic rhinitis, nasosinusitis, toothache, leukorrhagia, and pyocutaneous disease with swelling and pain. Rihuazi Bencao: for treating pterygium, traumatic injury, hemorrhage, acute mastitis, hair and back, scrofula, intestinal wind, hemorrhoid, fistula, pus discharge, cellulitis, scabies, pain relieving, granulation promoting, and scar removing.
Bletilla striata: bitter, sweet, astringent and slightly cold. It enters lung, liver and stomach meridians. Astringe to stop bleeding, resolve swelling and promote tissue regeneration. Can be used for treating hemoptysis, hematemesis, traumatic hemorrhage, pyocutaneous disease, toxic swelling, and chapped skin. Shen nong Ben Cao Jing: "predominate superficial infection, malignant sore, abscess, impairment of yin and death muscle, pathogenic qi in stomach"; compendium of materia Medica: its smell is bitter, mild and non-toxic.
Tribulus terrestris: pungent, bitter and slightly warm; has little toxicity. It enters liver meridian. Calming the liver, relieving depression, promoting blood circulation, expelling pathogenic wind, improving eyesight, and relieving itching. Can be used for treating headache, vertigo, distending pain in chest and hypochondrium, milk retention, mammary abscess, conjunctival congestion, nebula, rubella and pruritus.
White muscardine silkworm: salty, pungent and even. It enters liver, lung and stomach meridians. Extinguish wind and stop spasm, dispel wind and alleviate pain, resolve phlegm and dissipate nodulation. Can be used for treating liver wind with phlegm, epilepsy and convulsion, infantile acute convulsion, tetanus and apoplexy
Figure RE-GDA0002479335240000061
Headache due to wind-heat, conjunctival congestion, pharyngalgia, pruritus due to rubella, and parotitis.
Tuckahoe, poria cocos: sweet, bland and mild. It enters heart, lung, spleen and kidney meridians. Induce diuresis and drain dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia. Modern medical research: poria can enhance immunity, and pachyman has obvious effects of resisting tumor and protecting liver. Poria cocos, with sweet, bland and mild nature and taste, enters heart, lung and spleen meridians. Has effects of eliminating dampness, promoting diuresis, invigorating spleen, regulating stomach function, calming heart, and tranquilizing mind. Can be used for treating dysuria, edema, fullness, phlegm retention, cough, vomiting, nausea, diarrhea, spermatorrhea, stranguria with turbid urine, palpitation, and amnesia. Tuckahoe, which is different from other traditional Chinese medicines that induce diuresis directly, induces diuresis by strengthening the spleen and lung. For diarrhea due to spleen deficiency, leukorrhagia with tuckahoe can both strengthen spleen and drain dampness, and for diarrhea and leukorrhagia due to dysfunction of transportation and transformation due to spleen deficiency, it is combined with dangshen, Bai Zhu and shan Yao, etc., because it has the action of treating both principal and secondary aspects of disease. It can be used as an adjuvant drug for tonifying lung and spleen and treating qi deficiency.
Giant typhonium rhizome: pungent and warm; is toxic. It enters stomach and liver meridians. Dispel wind-phlegm, arrest convulsion, remove toxicity, dissipate nodulation and alleviate pain. In use forWind-phlegm obstructing the mouth and eyes
Figure RE-GDA0002479335240000062
Oblique, slurred speech, convulsions, epilepsy, tetanus, phlegm syncope, headache, migraine, scrofula, subcutaneous nodule, and venomous snake bite.
Ampelopsis japonica: bitter and slightly cold. It enters heart and stomach meridians. Clearing away heat and toxic material, resolving carbuncle and dissipating stagnation, healing sore and promoting granulation. It can be used for treating carbuncle, cellulitis, furuncle, scrofula, burn, and scald. Modern researches show that the composition has an inhibitory effect on dermatophytes.
Dittany bark: bitter and cold. It enters spleen, stomach and bladder meridians. Clear heat and dry dampness, dispel wind and remove toxicity. Can be used for treating damp-heat sore, yellow water dripping, eczema, rubella, scabies, sore, rheumatism, heat arthralgia, jaundice, and dark urine.
White ugly: bitter and cold; is toxic. It enters lung, kidney and large intestine meridians. Purge water and relieve constipation, resolve phlegm and purge water, kill parasites and eliminate accumulation. Can be used for treating edema, constipation, phlegm and fluid accumulation, asthma, cough, and abdominal pain due to parasitic infestation.
White atractylodes rhizome: bitter, sweet and warm. It enters spleen and stomach meridians. Invigorate spleen, replenish qi, dry dampness, induce diuresis, stop sweating, prevent abortion. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion. Bighead atractylodes rhizome, Bighead Atractylodes rhizome, Yao Lun (treatise on the property of medicine), has the effect of pleasing the main face and removing black patch.
Safflower: pungent and warm. It enters heart and liver meridians. Promoting blood circulation, dredging channels, removing blood stasis and relieving pain. Can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and swelling and pain due to pyocutaneous disease.
Peach kernel: bitter, sweet and neutral. It enters heart, liver and large intestine meridians. Promote blood circulation to remove blood stasis, moisten intestines to relieve constipation, relieve cough and relieve asthma. Can be used for treating amenorrhea, dysmenorrhea, abdominal mass, pulmonary abscess, intestinal abscess, traumatic injury, constipation due to intestinal dryness, cough, and asthma.
White gourd seeds: sweet in taste; slightly cold in nature. Entering the lung; the large intestine channel. Clearing lung and eliminating phlegm; carbuncle eliminating and pus discharging; to remove dampness. Cough due to phlegm-heat; pulmonary abscess; intestinal abscess; white turbidity; leucorrhea; beriberi; edema; stranguria syndrome. Rihuazi Bencao: remove the black patch and moisten the skin. Compendium (compendium): it is indicated for intestinal abscess. Ben Cao Jing Shu (the book of materia Medica Prime and Dredging): can stimulate the appetite and wake up the spleen. The semen Benincasae has good health promoting and antiaging effects.
Dried rehmannia root: sweet and cold in nature. It enters heart, liver and kidney meridians. Clear heat and cool blood, nourish yin and promote the production of body fluid. Can be used for treating heat entering nutrient-blood, epidemic febrile disease, macula, hematemesis, epistaxis, yin injury due to fever, crimson tongue, polydipsia, constipation due to body fluid consumption, fever due to yin deficiency, bone steaming, fatigue, internal heat, and diabetes.
Peach blossom: bitter and neutral. A core; liver; the large intestine channel. Diuresis; promoting blood circulation and removing blood stasis. Major edema; beriberi; phlegm-fluid retention; promoting diuresis and relaxing bowels; spraying sand and stone; constipation; amenorrhea; mania; sores and rashes. In the book of Shen nong Ben Cao Jing, peach blossom has the effect of making people look good.
And (3) rose: sweet, slightly bitter and warm. It enters liver and spleen meridians. Move qi and relieve depression, harmonize blood, alleviate pain. Can be used for treating liver and stomach qi pain, anorexia, emesis, menoxenia, traumatic injury, and pain.
Holy basil incense: pungent and sweet with warm nature. Enter the lung. Dispel wind-cold, avoid dirty. It can be used for treating typhoid fever, common cold, headache, fullness and distention of chest and abdomen, diarrhea, nocturnal emission, nasal obstruction, and toothache. Strong aromatic smell, also called as incense, can avoid dirty and eliminate turbid.
Peony: bitter; diluting; and (7) flattening. It enters liver meridian. Promoting blood circulation to regulate menstruation. Menoxenia of primary women; abdominal pain during menstruation.
Chamomile: slightly bitter and sweet. Enter liver, kidney and lung meridians. Tranquilizing, improving sleep, relieving pain, relieving allergy, caring skin, repairing sensitive skin, and reducing red blood streak.
Rhodiola root: sweet, bitter and neutral. It enters lung and heart meridians. Tonify qi, activate blood, dredge vessels and relieve dyspnea. Can be used for treating qi deficiency, blood stasis, thoracic obstruction, cardiodynia, apoplexy, hemiplegia, listlessness, and asthma.
Lavender: 2, pungent taste; is cool in nature. Clearing away heat and toxic materials; dispel wind and relieve itching. Mainly treats headache; dizziness; sores in the mouth and tongue; red and swollen throat; scald by hot water or fire; rubella; scabies and tinea.
Ginseng: sweet, slightly bitter and neutral. It enters spleen, lung and heart meridians. The ginseng has the following effects: tonify primordial qi, recover pulse to stop collapse, tonify spleen and lung, promote fluid production, and induce tranquilization.
Olive oil: sweet, sour, astringent, mild and nontoxic. Meridian tropism: entering lung and stomach. The efficacy is as follows: promoting the production of body fluid, relieving restlessness and fever, stimulating appetite, lowering qi, clearing heat from throat, quenching thirst, resolving bone, relieving diarrhea, removing toxic substance, and relieving hangover. The main treatment is as follows: hot pain in the throat, dry mouth and tongue, food stagnation and diarrhea, fishbone sticking to the throat, poisoning of the fish and turtle, and alcoholism. The olive oil contains vitamin E and antioxidant components, so that it can protect skin, especially prevent skin damage and aging, make skin glossy, nourish eyelash, and make it dense and long.
Coptis chinensis: bitter and cold. It enters heart, spleen, stomach, liver, gallbladder and large intestine meridians. Clear heat and dry dampness, purge fire and remove toxicity. Can be used for treating damp-heat distention and fullness, emesis, acid regurgitation, dysentery, jaundice, hyperpyrexia, excessive heart-fire, vexation, insomnia, palpitation, hematemesis, epistaxis, conjunctival congestion, toothache, diabetes, carbuncle, swelling, and furuncle; it is used externally to treat eczema, eczema and purulent ear canal. Huang Lian (Chinese goldthread) processed with wine is good at clearing heat in upper energizer. It can be used for treating conjunctival congestion and aphtha. Jiang Huang Lian can clear stomach, harmonize stomach and stop vomiting. Can be used for treating cold and heat accumulation, damp-heat obstruction, fullness and emesis. Yu Huang Lian soothes liver, harmonizes stomach and stops vomiting. Can be used for treating liver and stomach disharmony, emesis and acid regurgitation.
Rhizoma atractylodis: pungent, bitter and warm. It enters spleen, stomach and liver meridians. Dry dampness and invigorate spleen, dispel wind and cold, improve vision. Can be used for treating damp obstruction of middle warmer, abdominal distention, diarrhea, edema, tinea pedis atrophy 36484m, rheumatalgia, wind-cold type common cold, night blindness, dim eyesight, and astringency.
Examples of the experiments
The traditional Chinese medicine composition comprises the following components: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of cortex dictamni, 5 parts of white muscardine silkworm, 5 parts of poria alba, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower carthamus, 15 parts of Chinese waxgourd seed, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender and 20 parts of ginseng.
The traditional Chinese medicine composition and the olive oil mixture: the traditional Chinese medicine composition is ground into powder, sieved by a 200-mesh sieve and mixed with 510 parts of olive oil.
The first traditional Chinese medicine essential oil: putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria, safflower and holy basil in the traditional Chinese medicine composition into a gauze bag, putting the gauze bag into 255 parts of olive oil, performing ultrasonic extraction, keeping the temperature at 50 ℃, and extracting for 8 hours; decocting fructus Atriplicis Sibiricae, rhizoma Typhonii and semen Pharbitidis with 5 times of water for 1 hr, filtering, mixing the filtrate with 255 parts of oleum Olivarum, stirring for 0.5 hr, standing, layering, and collecting organic phase; pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve; mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus.
And (2) traditional Chinese medicine essential oil II: putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria, safflower and holy basil in the traditional Chinese medicine composition into a gauze bag, putting the gauze bag into 255 parts of olive oil, performing ultrasonic extraction, keeping the temperature at 50 ℃, and extracting for 8 hours; decocting Tribulus terrestris, rhizoma Typhonii and semen Pharbitidis with 5 times of water for 1 hr, filtering, mixing the filtrate with 255 parts of olive oil, stirring for 0.5 hr, mixing the filtrate with the rest part of olive oil, stirring, adjusting pH of water phase to 6.2-6.7 with hydrochloric acid or sulfuric acid, standing, layering, and collecting organic phase; pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve; mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus.
And (3) Chinese medicine essential oil III: pulverizing the traditional Chinese medicine composition, sieving with a 200-mesh sieve, mixing with 510 parts of olive oil, and soaking for 1 month; boiling the mixture in water for 10 h; soaking for 1 month.
Experimental example 1
60 female Kunming mice are taken, the body weight is 25-35g, the female Kunming mice are randomly divided into 6 groups for 6 weeks, 10 groups are taken, a group 1 is that the back hair is removed by 10% NaS2 aqueous solution, 1 block of skin is exposed, the area is about 1.5cm × 1.5.5 cm, the mice are irradiated for 1 time by medium wave Ultraviolet (UVB) with the wavelength of 320nm, the binding irradiation time is 60min continuously for 30 days, a group 2 is that the unhairing and irradiation treatment of the same group 1 are carried out, 1ml of olive oil is coated on the unhairing position every day, a group 3 is that the unhairing and irradiation treatment of the same group 1 are carried out, 1ml of the traditional Chinese medicine composition and 1ml of the olive oil mixture are coated on the unhairing position of the mice every day, a group 4 is that the unhairing and irradiation treatment of the same group 1 are carried out, 1ml of the traditional Chinese medicine essential oil is coated on the unhairing position of the mice every day, a group 5 is that the unhairing and irradiation treatment of the same group 1 is carried out, two ml of the traditional Chinese medicine essential oil are coated on the unhairing position of the mice.
Promoting blood circulation and removing blood stasis:
TABLE 1 microcirculation restriction device for each group of mice
Group of Micro-artery caliber/mum Micro vein caliber/mum Number of capillaries/number
Group 1 25.25 85.45 3.2
Group 2 27.21 86.77 3.6
Group 3 29.43 114.64 6.1
Group 4 28.95 129.51 6.7
Group 5 28.58 129.35 6.6
Group 6 28.16 128.93 6.3
The results in table 1 show that groups 3-6 have significantly increased opening numbers of the micro-venous orifices and the capillaries (P is less than 0.01) compared with group 1, which indicates that the traditional Chinese medicine composition can improve microcirculation and has the functions of promoting blood circulation and removing blood stasis; compared with the group 3, the groups 4-6 have obvious increase (P is less than 0.01) on the opening number of the micro veins and the capillary vessels, which shows that the preparation method of the Chinese medicinal essential oil I, the Chinese medicinal essential oil II and the Chinese medicinal essential oil III can extract the effective components of the Chinese medicinal composition for promoting blood circulation and removing blood stasis better than the preparation method of the Chinese medicinal composition and the olive oil mixture.
The skin aging delaying effect is as follows:
TABLE 2 measurement of SOD content in skin tissue of mice in each group by xanthine oxidase method
Group of SOD (U/mg protein) in skin tissue
Group 1 81.56
Group 2 105.62
Group 3 132.45
Group 4 146.22
Group 5 147.27
Group 6 146.85
The results in Table 2 show that, compared with group 1, groups 2-6 all can increase the total SOD content of skin (P is less than 0.01), which indicates that the mixture of olive oil, the traditional Chinese medicine composition and olive oil can delay skin aging; compared with the group 2, the SOD activity of the groups 3-6 is obviously improved (P is less than 0.01), which shows that the traditional Chinese medicine composition can improve the total SOD content of the skin and delay the skin aging; compared with group 3, the SOD activity of groups 4-6 is significantly improved (P is less than 0.01), which indicates that the preparation method of the Chinese medicinal essential oil I, the Chinese medicinal essential oil II and the Chinese medicinal essential oil III can extract effective components more than the Chinese medicinal composition and the olive oil mixture, and promote the skin SOD activity to be improved.
Experimental example 2
60 female Kunming mice are taken, the body mass is 25-35g, the mice are randomly divided into 6 groups in 6 weeks, and each group comprises 10 mice. Group 7: making 2 round skin full-thickness wounds with the diameter of 0.5cm on the back of a mouse, observing the skin appearance healing condition on days 3, 7, 10 and 14 after the injury, measuring the change of the skin injury area and calculating the wound healing rate (the wound healing rate is the existing wound area/the initial wound area); group 8: treating with the same method as group 7, and applying 1ml of oleum Olivarum to the affected part daily; group 9: treating the affected part with the same treatment as in group 7, and applying 1ml of the Chinese medicinal composition and oleum Olivarum mixture to the affected part daily; group 10: treating with the same method as group 7, and applying 1ml of Chinese medicinal essential oil to the injured part every day; group 11: treating the affected part in the same way as in group 7, and applying two 1ml of Chinese medicinal essential oil to the affected part every day; group 12: the same treatment as in group 7 was carried out, and three 1ml of essential oil of Chinese herbs was applied to the affected part daily.
TABLE 3 comparison of wound healing rates of mice in each group at different time points
Group of 3-day healing Rate (%) Healing Rate for 7 days (%) 10-day healing Rate (%) Healing Rate for 14 days (%)
Group 7 36.36 61.23 80.44 90.25
Group 8 40.58 70.29 90.34 98.28
Group 9 67.12 80.37 96.73 100.00
Group 10 69.37 82.26 99.36 100.00
Group 11 78.66 90.89 100.00 100.00
Group 12 77.38 87.38 98.51 100.00
The results in table 3 show that, compared with group 7, group 8 has improved wound healing rate (P <0.01) on days 3, 7, 10 and 14, which indicates that olive oil has the function of improving wound healing, groups 9 to 12 have obviously improved wound healing rate (P <0.01) on days 3, 7, 10 and 14, and have basically healed on day 10, which indicates that the traditional Chinese medicine composition, the olive oil mixture, the traditional Chinese medicine essential oil I, the traditional Chinese medicine essential oil II and the traditional Chinese medicine essential oil III can promote wound healing; compared with the group 8, the wound healing rates of the groups 9-12 on the 3 rd, 7 th, 10 th and 14 th days are obviously improved (P is less than 0.01), which indicates that the olive oil is eliminated, the traditional Chinese medicine composition has the effect of promoting the wound healing, compared with the group 9, the wound healing rates of the groups 10-12 on the 3 rd, 7 th and 10 th days are obviously improved (P is less than 0.01), which indicates that the preparation method of the traditional Chinese medicine essential oil I and the traditional Chinese medicine essential oil II can improve the effective components for promoting the wound healing better than the preparation method of the traditional Chinese medicine composition and the olive oil mixture; in addition, the healing rate of group 11 on day 7 has reached 90%, which is better than that of group 10 (P <0.01), indicating that adjusting the pH value in the process of preparing the Chinese medicinal essential oil can effectively promote wound healing.
Experimental example 3
Preparing a lemon vinegar solution I: slicing 1 part of lemon by weight, and putting the sliced lemon into 1 part of rice vinegar for fermentation for 3 days; filtering to obtain fermentation liquor; mixing the fermentation liquor and water according to the volume ratio of 1: 10, and mixing.
Preparing a lemon vinegar solution II: slicing 1 part of lemon by weight, and putting the sliced lemon into 1 part of rice vinegar for fermentation for 3 days; filtering to obtain fermentation liquor; mixing the fermentation liquor and water according to the volume ratio of 1: 10, mixing; and adding sodium bicarbonate into the lemon vinegar solution, and adjusting the pH value to 6.4-6.8.
Table 4 measurement of pH of each group of mixtures
Figure RE-GDA0002479335240000111
Figure RE-GDA0002479335240000121
The results in table 4 show that the pH of the mixture of group 13, group 14 and group 17 is outside the optimum pH of the skin (4.5-6.5) (P <0.01), and the pH of the mixture of group 14, group 16 and group 18 is between the optimum pH of the skin (4.5-6.5) (P <0.01), so as to prevent the skin from being injured due to too high acidity, because sodium bicarbonate is added into the lemon vinegar solution to adjust the pH, and reacts with acetic acid to form sodium acetate, which forms a buffer system with acetic acid, and prevents the skin from being injured due to too low pH when the mixture is mixed with honey and Chinese medicinal essential oil.
Experimental example 4
The first traditional Chinese medicine composition comprises: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of white muscardine silkworm, 5 parts of white poria, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower, 15 parts of Chinese waxgourd seed, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender and 20 parts of ginseng.
And (2) a traditional Chinese medicine composition II: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of coptis chinensis, 5 parts of white muscardine silkworm, 5 parts of white poria, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower carthamus, 15 parts of Chinese waxgourd seed, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender and 20 parts of ginseng.
The third traditional Chinese medicine composition: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of rhizoma atractylodis, 5 parts of white muscardine silkworm, 5 parts of white poria, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower carthamus, 15 parts of semen benincasae, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender and 20 parts of ginseng.
The fourth traditional Chinese medicine composition: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of cortex dictamni, 5 parts of white muscardine silkworm, 5 parts of poria alba, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower carthamus, 15 parts of Chinese waxgourd seed, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender and 20 parts of ginseng.
Pulverizing the above Chinese medicinal compositions, sieving with 200 mesh sieve, mixing with 510 parts of olive oil, and making into mixture.
60 female Kunming mice are taken, the body mass is 25-35g, the mice are randomly divided into 6 groups in 6 weeks, and each group comprises 10 mice. Group 19: removing hair on the back of a mouse, dripping hot oil, making 2 circular scalds with the diameter of 0.5cm, observing the skin appearance healing condition on the 1 st, 3 th, 7 th and 10 th days after injury, measuring the change of the skin injury area and calculating the wound healing rate (the wound healing rate is the existing wound area/the initial wound area); group 20: treating with the same method as in group 19, and applying 1ml of oleum Olivarum to the affected part daily; group 21: treating with the same method as group 19, and applying 1ml of the mixture prepared by the Chinese medicinal composition I on the injured part every day; group 22: treating with the same method as group 19, and applying 1ml of mixture prepared from Chinese medicinal composition II on the affected part daily; group 23: treating with the same method as group 19, and applying 1ml of mixture prepared from Chinese medicinal composition III on the injured part daily; group 24: treating the affected part with the same treatment as in group 19, and applying 1ml of mixture prepared by the Chinese medicinal composition IV on the affected part daily.
TABLE 5 comparison of scald healing rates at different time points for each group of mice
Group of 1 day healing Rate (%) 3-day healing Rate (%) Healing Rate for 7 days (%) 10-day healing Rate (%)
Group 19 10.2 24.4 56.2 89.2
Group 20 13.4 25.5 58.7 90.1
Group 21 22.4 43.7 60.8 93.5
Group 22 30.5 50.6 78.9 95.2
Group 23 20.3 36.1 57.2 90.3
Group 24 63.7 97.4 100.0 100.0
The results in table 5 show that the groups 20-24 have improved wound healing rates (P <0.01) in days 1, 3, 7 and 10 compared with the group 19, which indicates that the olive oil, the first Chinese medicinal composition, the second Chinese medicinal composition, the third Chinese medicinal composition and the fourth Chinese medicinal composition can improve the healing effect of the wound; compared with the group 20, the wound healing rates of the groups 21, 22 and 24 are obviously improved (P is less than 0.01) in days 1, 3, 7 and 10, and surprisingly, the group 24 is basically healed in day 7, which shows that the function of discharging olive oil is realized, the effect of promoting the healing of the scald is better in the first traditional Chinese medicine composition, the second traditional Chinese medicine composition and the fourth traditional Chinese medicine composition, and the third traditional Chinese medicine composition does not have the obvious effect of promoting the healing of the scald. Compared with the group 21, the dittany bark is added in the group 24, the treatment effect is obviously improved (P is less than 0.01), the effects of the dittany bark, the coptis root and the rhizoma atractylodis are similar, the dittany bark in the group 24 is replaced by the coptis root in the group 22, the dittany bark in the group 24 is replaced by the rhizoma atractylodis in the group 23, and the scald treatment effect is better without the group 24 (P is less than 0.01).
The present invention will be described in detail below by way of examples.
Example 1
A traditional Chinese medicine composition comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of cortex dictamni, 5 parts of white muscardine silkworm, 5 parts of poria alba, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower carthamus, 15 parts of Chinese waxgourd seed, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender and 20 parts of ginseng.
A traditional Chinese medicine essential oil comprises the traditional Chinese medicine composition and 510 parts of olive oil. The preparation method of the traditional Chinese medicine essential oil comprises the following steps:
pulverizing the Chinese medicinal compositions, sieving with 200 mesh sieve, mixing with oleum Olivarum, and soaking for 1 month;
boiling the mixture in water for 10 h;
soaking for 1 month.
Example 2
A traditional Chinese medicine composition comprises the following components in parts by weight: 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of bighead atractylodes rhizome, 10 parts of pharbitis seed, 10 parts of ampelopsis japonica, 10 parts of cortex dictamni, 10 parts of white muscardine silkworm, 10 parts of white poria, 10 parts of rhizoma typhonii, 10 parts of tribulus terrestris, 20 parts of safflower, 20 parts of Chinese waxgourd seed, 30 parts of peach kernel, 30 parts of radix rehmanniae recen, 20 parts of rhodiola rosea, 30 parts of chamomile, 30 parts of rose, 30 parts of peony, 30 parts of peach blossom, 30 parts of lavender and 50 parts of ginseng.
A Chinese medicinal essential oil comprises the above Chinese medicinal composition and 1000 parts of oleum Olivarum. The preparation method of the traditional Chinese medicine essential oil comprises the following steps:
pulverizing the Chinese medicinal compositions, sieving with 200 mesh sieve, mixing with oleum Olivarum, and soaking for 2 months;
boiling the mixture for 12h in water;
soaking is continued for 45 days.
Example 3
A traditional Chinese medicine composition comprises the following components in parts by weight: 15 parts of angelica dahurica, 15 parts of bletilla striata, 15 parts of bighead atractylodes rhizome, 15 parts of pharbitis seed, 15 parts of ampelopsis japonica, 15 parts of cortex dictamni, 20 parts of white muscardine silkworm, 15 parts of poria alba, 15 parts of rhizoma typhonii, 10 parts of tribulus terrestris, 25 parts of safflower, 25 parts of Chinese waxgourd seed, 35 parts of peach kernel, 35 parts of radix rehmanniae recen, 25 parts of rhodiola rosea, 35 parts of chamomile, 35 parts of rose, 35 parts of peony, 35 parts of peach blossom, 35 parts of lavender and 70 parts of ginseng.
A Chinese medicinal essential oil comprises the above Chinese medicinal composition and olive oil 1620 parts. The preparation method of the traditional Chinese medicine essential oil comprises the following steps:
pulverizing the Chinese medicinal compositions, sieving with 200 mesh sieve, mixing with oleum Olivarum, and soaking for 3 months;
boiling the mixture for 12h in water;
soaking for 2 months.
Example 4
A traditional Chinese medicine essential oil comprises the following components:
the traditional Chinese medicine composition comprises the following components: 5 parts of angelica dahurica, 5 parts of bletilla striata, 5 parts of bighead atractylodes rhizome, 5 parts of pharbitis seed, 5 parts of ampelopsis japonica, 5 parts of cortex dictamni, 5 parts of white muscardine silkworm, 5 parts of poria alba, 5 parts of rhizoma typhonii, 5 parts of tribulus terrestris, 15 parts of safflower carthamus, 15 parts of Chinese waxgourd seed, 20 parts of peach kernel, 20 parts of radix rehmanniae recen, 15 parts of rhodiola rosea, 20 parts of chamomile, 20 parts of rose, 20 parts of peony, 20 parts of peach blossom, 20 parts of lavender, 20 parts of ginseng and 20 parts of holy basil;
255 parts of the traditional Chinese medicine composition and 510 parts of olive oil.
The preparation method of the traditional Chinese medicine essential oil comprises the following steps:
putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria, safflower and holy basil into a gauze bag, putting the gauze bag into 255 parts of olive oil, carrying out ultrasonic extraction, keeping the temperature at 50 ℃, and extracting for 8 hours;
decocting fructus Atriplicis Sibiricae, rhizoma Typhonii and semen Pharbitidis with 5 times of water for 1 hr, filtering, mixing the filtrate with 255 parts of oleum Olivarum, stirring for 0.5 hr, standing, layering, and collecting organic phase;
pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve;
mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus, and making into Chinese medicinal essential oil.
Example 5
A traditional Chinese medicine essential oil comprises the following components:
the traditional Chinese medicine composition comprises the following components: 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of bighead atractylodes rhizome, 10 parts of pharbitis seed, 10 parts of ampelopsis japonica, 10 parts of cortex dictamni, 10 parts of white muscardine silkworm, 10 parts of poria alba, 10 parts of rhizoma typhonii, 10 parts of tribulus terrestris, 20 parts of safflower carthamus, 20 parts of Chinese waxgourd seed, 30 parts of peach kernel, 30 parts of radix rehmanniae recen, 20 parts of rhodiola rosea, 30 parts of chamomile, 30 parts of rose, 30 parts of peony flower, 30 parts of peach blossom, 30 parts of lavender, 50 parts of ginseng and 25 parts of holy basil;
420 parts of the traditional Chinese medicine composition and 1000 parts of olive oil.
The preparation method of the traditional Chinese medicine essential oil comprises the following steps:
putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria, safflower and holy basil into a gauze bag, putting the gauze bag into 500 parts of olive oil, carrying out ultrasonic extraction, keeping the temperature at 40 ℃, and extracting for 8 hours;
decocting fructus Atriplicis Sibiricae, rhizoma Typhonii and semen Pharbitidis with 8 times of water for 1 hr, filtering, mixing the filtrate with 500 parts of oleum Olivarum, stirring for 45 min, standing, layering, and collecting organic phase;
pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve;
mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus, and making into Chinese medicinal essential oil.
Example 6
A traditional Chinese medicine essential oil comprises the following components:
the traditional Chinese medicine composition comprises the following components: 15 parts of angelica dahurica, 15 parts of bletilla striata, 15 parts of bighead atractylodes rhizome, 15 parts of pharbitis seed, 15 parts of ampelopsis japonica, 15 parts of cortex dictamni, 20 parts of white muscardine silkworm, 15 parts of poria alba, 15 parts of rhizoma typhonii, 10 parts of tribulus terrestris, 25 parts of safflower, 25 parts of Chinese waxgourd seed, 35 parts of peach kernel, 35 parts of radix rehmanniae recen, 25 parts of rhodiola rosea, 35 parts of chamomile, 35 parts of rose, 35 parts of peony flower, 35 parts of peach blossom, 35 parts of lavender, 70 parts of ginseng and 30 parts of holy basil;
540 parts of the traditional Chinese medicine composition and 1620 parts of olive oil.
The preparation method of the traditional Chinese medicine essential oil comprises the following steps:
putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria, safflower and holy basil into a gauze bag, putting the gauze bag into 1080 parts of olive oil, carrying out ultrasonic extraction, keeping the temperature at 60 ℃, and extracting for 8 hours;
decocting fructus Atriplicis Sibiricae, rhizoma Typhonii and semen Pharbitidis with 10 times of water for 1 hr, filtering, mixing the filtrate with 540 parts of oleum Olivarum, stirring for 1 hr, standing, layering for 2 layers, and collecting organic phase;
pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve;
mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus, and making into Chinese medicinal essential oil.
Example 7
The same components as in example 4 were used, with the following differences in the preparation: (ii) a
Before the medicine is put into a gauze bag, removing pedicels of chamomile, rose, peony and peach flower, removing impurities of lavender, grinding peach kernel and Chinese waxgourd seed, and crushing radix rehmanniae, rhodiola rosea and ginseng into small pieces.
By adopting the scheme, the medicine is crushed into small blocks, and the small blocks are blocks with the diameter smaller than 1cm, so that the extraction efficiency is improved, and the influence of impurities is removed.
Example 8
The same procedure as for example 7 was followed with the following differences:
mixing the filtrate with the rest part of oleum Olivarum, and adjusting pH of the water phase to 6.2-6.7 with hydrochloric acid or sulfuric acid.
By adopting the scheme, the pH is adjusted to enable the organic acid to be dissociated and enter the olive oil, so that the extraction rate of the effective components is improved.
Example 9
The traditional Chinese medicine skin care product comprises the following components by volume:
10 parts of lemon vinegar solution, 1 part of traditional Chinese medicine essential oil in example 1 and 5 parts of honey.
The preparation method of the traditional Chinese medicine skin care product comprises the following steps:
mixing the components, wherein the preparation method of the lemon vinegar solution comprises the following steps:
slicing 1 part of lemon by weight, and putting the sliced lemon into 1 part of rice vinegar for fermentation for 3 days;
filtering to obtain fermentation liquor;
mixing the fermentation liquor and water according to the volume ratio of 1: 10, and mixing.
Example 10
The traditional Chinese medicine skin care product comprises the following components by volume:
15 parts of lemon vinegar solution, 2 parts of Chinese medicinal essential oil in example 4 and 8 parts of honey.
The preparation method of the traditional Chinese medicine skin care product comprises the following steps:
mixing the components, wherein the preparation method of the lemon vinegar solution comprises the following steps:
slicing 2 parts of lemon by weight, and putting into 3 parts of rice vinegar for fermentation for 5 days;
filtering to obtain fermentation liquor;
mixing the fermentation liquor and water according to the volume ratio of 1: 15, and mixing.
Example 11
The traditional Chinese medicine skin care product comprises the following components by volume:
20 parts of lemon vinegar solution, 3 parts of traditional Chinese medicine essential oil in example 8 and 10 parts of honey.
The preparation method of the traditional Chinese medicine skin care product comprises the following steps:
mixing the components, wherein the preparation method of the lemon vinegar solution comprises the following steps:
slicing 3 parts of lemon by weight, and putting the sliced lemon into 5 parts of rice vinegar for fermentation for 6 days;
filtering to obtain fermentation liquor;
mixing the fermentation liquor and water according to the volume ratio of 1: 20 and mixing.
Example 12
The difference is substantially the same as in example 10:
and adding sodium bicarbonate into the lemon vinegar solution, and adjusting the pH value to 6.4-6.8.
Example 13
10 volunteers, who were scalded by hot water or fire, were smeared with 1ml of the essential oil of the Chinese medicine of example 1, and showed pain relief for five minutes, and a clear improvement was observed on the second day.
Example 14
10 volunteers with small area incised wound smeared with 1ml of the essential oil of the traditional Chinese medicine in the embodiment 4, the pain is relieved within about five minutes, and the improvement is obvious on the next day.
Example 15
10 volunteers with eczema were smeared with 1ml of the essential oil of the Chinese herbal medicine of example 8, and itching was relieved in about 10 minutes, and the third day was obviously improved.
Example 16
10 volunteers, wearing their feet to get blisters, smeared with 1ml of the essential oil of the Chinese medicine of example 8, and the blisters disappeared the next day.
Example 17
20 volunteers, who were bruised by falls, were smeared with 1ml of the essential oil of the traditional Chinese medicine of example 8, and the bruised green was improved remarkably the next day.
Example 18
20 volunteers, bitten by mosquitoes, smeared with 1ml of the essential oil of the traditional Chinese medicine in the embodiment 8, relieve itching for about 3 minutes, and the red packet disappears in the same day.
Example 19
20 volunteers have chloasma, 15-20ml of the traditional Chinese medicine skin care product in the embodiment 9 is applied to the face every day, the face lasts for 45 days, the chloasma becomes shallow obviously in 17 people, and the effective rate accounts for 85%.
Example 20
20 volunteers with acne are smeared on the face with 15-20ml of the traditional Chinese medicine skin care product in the embodiment 10 every day, and 20 acne is obviously improved after the face lasts for 45 days.
Example 21
50 volunteers have dry face and fine lines, 15-20ml of the traditional Chinese medicine skin care product in the embodiment 12 is smeared on the face every day for 45 days, and 49 skin with the fine lines obviously reduced becomes smooth and white.
It should be noted that, for those skilled in the art, it is possible to make several improvements and modifications to the present invention without departing from the principle of the present invention, and those improvements and modifications also fall within the protection scope of the claims of the present invention.

Claims (10)

1. A traditional Chinese medicine composition is characterized in that: the traditional Chinese medicine composition comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of bletilla striata, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of pharbitis seed, 5-15 parts of Japanese ampelopsis, 5-15 parts of dittany bark, 5-20 parts of white muscardine silkworm, 5-15 parts of white poria, 5-15 parts of rhizoma typhonii, 5-10 parts of tribulus terrestris, 15-25 parts of safflower, 15-25 parts of Chinese waxgourd seed, 20-35 parts of peach kernel, 20-35 parts of radix rehmanniae, 15-25 parts of rhodiola rosea, 20-35 parts of chamomile, 20-35 parts of rose, 20-35 parts of peony flower, 20-35 parts of peach blossom, 20-35 parts of lavender and 20-70 parts of ginseng.
2. The traditional Chinese medicine composition according to claim 1, characterized in that: the traditional Chinese medicine composition comprises the following components in parts by weight: 10 parts of angelica dahurica, 10 parts of bletilla striata, 10 parts of bighead atractylodes rhizome, 10 parts of pharbitis seed, 10 parts of ampelopsis japonica, 10 parts of cortex dictamni, 10 parts of white muscardine silkworm, 10 parts of white poria, 10 parts of rhizoma typhonii, 10 parts of tribulus terrestris, 20 parts of safflower, 20 parts of Chinese waxgourd seed, 30 parts of peach kernel, 30 parts of radix rehmanniae recen, 20 parts of rhodiola rosea, 30 parts of chamomile, 30 parts of rose, 30 parts of peony, 30 parts of peach blossom, 30 parts of lavender and 50 parts of ginseng.
3. A traditional Chinese medicine essential oil is characterized in that: comprises the following components:
the traditional Chinese medicine composition of any one of claims 1-2, in a ratio of 1: (2-3).
4. A method for preparing the essential oil of the traditional Chinese medicine according to claim 3, which is characterized by comprising the following steps: the method comprises the following steps:
pulverizing the Chinese medicinal materials, sieving with 200 mesh sieve, mixing with oleum Olivarum, and soaking for 1-3 months;
boiling the mixture in water for 10-14 h;
continuing soaking for 1-2 months.
5. A method for preparing the essential oil of the traditional Chinese medicine according to claim 3, which is characterized by comprising the following steps: the method comprises the following steps:
putting chamomile, rose, peony, peach blossom, lavender, peach kernel, Chinese waxgourd seed, radix rehmanniae, rhodiola rosea, ginseng, angelica dahurica, bletilla striata, bighead atractylodes rhizome, Japanese ampelopsis root, dittany bark, white poria and safflower into a gauze bag, putting the gauze bag into olive oil with the weight of 1-2 times of the total weight of the medicaments, performing ultrasonic extraction, and extracting for 8 hours;
decocting fructus Atriplicis Sibiricae, rhizoma Typhonii, and semen Pharbitidis with 5-10 times of water for 1 hr, filtering, mixing the filtrate with the rest amount of oleum Olivarum, stirring for 0.5-1 hr, standing, layering, and collecting organic phase;
pulverizing Bombyx Batryticatus, and sieving with 200 mesh sieve;
mixing oleum Olivarum extracted by ultrasonic, oleum Olivarum collected by layers, and Bombyx Batryticatus, and making into Chinese medicinal essential oil.
6. The method for preparing essential oil of traditional Chinese medicine according to claim 5, which is characterized in that: and in the ultrasonic extraction process, keeping the temperature at 40-60 ℃.
7. The method for preparing essential oil of Chinese traditional medicine according to claim 6, which is characterized in that: before the medicine is put into a gauze bag, removing pedicels of chamomile, rose, peony and peach flower, removing impurities of lavender, grinding peach kernel and Chinese waxgourd seed, and crushing radix rehmanniae, rhodiola rosea and ginseng into small pieces.
8. The method for preparing essential oil of traditional Chinese medicine according to claim 7, which is characterized in that: mixing the filtrate with the rest part of oleum Olivarum, and adjusting pH of the water phase to 6.2-6.7 with hydrochloric acid or sulfuric acid.
9. A traditional Chinese medicine skin care product is characterized in that: the traditional Chinese medicine skin care product comprises the following components in percentage by volume:
10-20 parts of lemon vinegar solution, 1-3 parts of the traditional Chinese medicine essential oil according to claim 3 and 5-10 parts of honey.
10. The traditional Chinese medicine skin care product according to claim 9, which is characterized in that: the preparation method of the lemon vinegar solution comprises the following steps:
slicing 1-3 parts of lemon by weight, and fermenting in 1-5 parts of rice vinegar for 3-6 days;
filtering to obtain fermentation liquor;
mixing the fermentation liquor and water according to the volume ratio of 1: (10-20) mixing.
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CN113925826A (en) * 2021-12-02 2022-01-14 成都华神科技集团股份有限公司 Moisturizing and hydrating composition, mask and preparation method and application of mask
CN113925826B (en) * 2021-12-02 2024-02-27 成都华神科技集团股份有限公司 Moisturizing and moisturizing composition, mask and preparation method and application thereof

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