CN105412605A

CN105412605A - Traditional Chinese medicine mask capable of promoting blood circulation, beautifying and removing freckles and preparation method thereof

Info

Publication number: CN105412605A
Application number: CN201510953266.2A
Authority: CN
Inventors: 赵玉妹
Original assignee: Qingdao Anbeikang Biomedical Technology Co Ltd
Current assignee: Qingdao Anbeikang Biomedical Technology Co Ltd
Priority date: 2015-12-17
Filing date: 2015-12-17
Publication date: 2016-03-23

Abstract

The invention discloses a traditional Chinese medicine mask capable of promoting blood circulation, beautifying and removing freckles. The traditional Chinese medicine mask is prepared from the following raw materials in parts by weight: 10 to 20 parts of rose, 10 to 20 parts of angelica sinensis, 10 to 20 parts of rhodiola rosea, 10 to 20 parts of ligusticum wallichii, 10 to 20 parts of astragalus membranaceus, 10 to 20 parts of albizia julibrissin, 10 to 20 parts of silkworm larva, 10 to 20 parts of leenurus heterophyllus, 10 to 20 parts of geranium, 10 to 20 parts of radix saposhnikoviae, 10 to 20 parts of common bletilla tuber, 10 to 20 parts of bighead atractylodes rhizome, 10 to 20 parts of radix paeoniae alba, 10 to 20 parts of radix ampelopsis, 10 to 20 parts of radix angelicae pubescentis, 10 to 20 parts of radix angelicae dahuricae, 10 to 20 parts of safflower carthamus, 10 to 20 parts of rosa chinensis, 10 to 20 parts of common perilla and 10 to 20 parts of tribulus terrestris. According to the traditional Chinese medicine mask disclosed by the invention, the goals of removing freckles to beautify, promoting blood circulation to remove blood stasis and beautifying the face are achieved by regulating qi, promoting blood circulation, activating and harmonizing qi-blood and dredging channels; through external use, the traditional Chinese medicine mask disclosed by the invention has the effects of promoting blood and qi circulation and removing freckles and acnes.

Description

Face mask of traditional Chinese medicine of a kind of skin care speckle removing of invigorating blood circulation and preparation method thereof

Technical field

The present invention relates to the medicinal preparation containing deriving from plant, animal or mineral component, particularly a kind of face mask of traditional Chinese medicine and preparation method thereof of skin care speckle removing of invigorating blood circulation.

Background technology

Freckle-removing mask refers to the nutrition by there being light speckle spot-removal function, is added in the facial film become by various material-making.And facial film is using the carrier as this nutrition, after allowing nutrition be absorbed by the skin, reach and subtract light effect with eliminating pigmented spots on the face.

At different age levels, easily there is dissimilar speckle in people on the face.Common pigmented spots include: nevus fuscoceruleus ophthalmomaxillaris, freckle, sunburn, senile plaque.Pigmented spots are caused by a variety of factor: one is relevant with heredity, and some pigmented dermatosis of parents entails the next generation; Two is that endocrine disturbance causes pigmentation; Three is erratic living habit, and long stress causes cutaneous pigmentation; Four is cicatrixes that wound, acne etc. stay, and also can leave pigmentation.Vitamin C is oxidant, can suppress the Oxidation of DOPA quinone in skin, makes the dark oxidized form pigment in skin be converted into reduced form light color element, the formation of check melanin.Whitening and speckle dispelling is the life career of women, and no matter you are 20,30 or 40, and you also can not weaken with advancing age to the requirement of whitening.The puzzlement of mottle is not one day two days, and we can not ignore the effect of freckle-removing mask dispelling stain, and its intensively can inject light speckle element, the formation of check melanin for skin.The nursing that facial masks for whitening faces and removing spots of the present invention can give skin the most natural, safety is direct again.Beauties could also select different allotment materials according to the skin quality state of oneself, and whitening and speckle dispelling effect is more effective! Pure natural material, helps you to gather in the crops tender white muscle skin, helps you to save cost, make snow-white skin.

Chloasma, butterfly spot belong to dermatology common disease, and pathogenesis it be not immediately clear.Modern medicine is thought may be relevant with many factors such as endocrine disturbance, heredity, D&C, some chronic disease, ultraviolet excessive radiation.Wherein endocrine disturbance is primary pathogenic factors.Namely pigmented spots can be multiple at first, tend to merge form not of uniform size, irregular patch, are symmetrically distributed in the face exposing and expose.The most outstanding with cheekbone portion, forehead, two cheeks, sometimes in butterfly wing, occasionally in upper lip.Clear-cut margin or in diffusivity, local NIP and squama.No conscious sympton, pigment can slightly change with factors such as season, Exposure to Sunlight, hormonal changes, does not often prolongedly move back, and a part is in point puerperium or can slowly disappear after withdrawing contraceptive.

The butterfly spot cause of disease it be unclear that, and is more common in women, and in blood, estrogen level height is main cause.Its morbidity is relevant with gestation, Long-term Oral contraceptive, menoxenia.Also the patients such as some female reproductive system illness, tuberculosis, cancer, chronic alcoholism, hepatopathys are seen.Daylight can impel morbidity.Male patient accounts for 10%, and having research to think, that male falls ill is relevant with heredity.Infringement is yellowish-brown or dark brown patch, and be often symmetrically distributed in cheekbone buccal, also can involve socket of the eye week, forehead, upper lip and nose, edge is generally more obvious.Without subjective symptom and general malaise.The mottle depth and season, Exposure to Sunlight, endocrine factors is relevant.Psychentonia, stays up late, and fatigue can increase the weight of skin lesion.

Chloasma is a kind of metabolism of pigment abnormity dermatosis betiding face, and show as the yellowish-brown or light black patch of symmetry that facial area size does not wait, divide on skin, that comforts is not in the way.Primary disease is called " chloasma ", " chloasma hepaticum ", " dusty face " etc. by motherland's medical science.The cause of disease of the functional disorders such as the existing obvious endocrine of the generation due to primary disease, nervous system or digestive system can be followed, the chemical factors being subject to again many external worlds, as the impact of Exposure to Sunlight, thermal radiation, wound (scratch, friction etc.), contact photosensitizer or compound, the agent of external silvery, mercurial etc., therefore generally advocates treatment of the inside combined with the outside.

Said ailment said due to cold or exposure is like can understand from the angle of broad sense in the etiology and pathogenesis of butterfly spot, chloasma for the traditional Chinese medical science, and the Exposure to Sunlight be familiar with as modern medicine, thermal radiation, contact photosensitizer or compound, the agent of external silvery, mercurial etc., all can be summed up as ailment said due to cold or exposure.Therefore, the medicine for external use controlled for ailment said due to cold or exposure can also in conjunction with modern pharmacology result of study, compatibility anti-ultraviolet, radiation-resistant medicine.Also should take the circumstances into consideration to add said medicine to make treatment have something to base in conjunction with the achievement in research of modern pharmacology in formula.In addition, for exfoliative medicine, as Radix Aconiti Lateralis Preparata, Fructus Mume etc., because its Skin peeling effect can cause skin injury, easily cause the pigmentation of skin thus increase the weight of symptom, should be cautious use of.

At present, most research is thought, chloasma is that melanocyte and melanosome all increase, and then show mottle due to patient with chloasma cutaneous lesion melanocyte increased activity.Under pathological state, intradermal macrophage can engulf the melanosome being dropped into corium, or calmness is in dermis, or at intracellular degradation, a part is through lymph metastasis.Generation and the excretion disequilibrium of pigment, and be gathered in the part in epidermis cell superfluously, just form pigmentation.Melanic excretion has two approach: one is drain in kidney, and another is discharged through skin, and namely melanin is transferred in keratoprotein, migrates to horny layer with epidermal growth, finally renews with the horny layer cycle and comes off.The method for the treatment of chloasma comprise acupuncture and tuina-massage (as local acupuncture, body acupuncture, acupoint injection therapy, cup, scrape therapy, massage, SHENQUE acupoint stick, sunken cord, imbedding needle, the ear acupoint etc.), external treatment (as cream, facial film, lotion, stifling side) and decoction for the treatment etc.Existing square medicated bag draws together XIAOYAO POWDER, JIAWEI XIAOYAO SAN, LIUWEI DIHUANG TANG, TAOHONG SIWU TANG, decoction for removing blood stasis, ERZHI WAN, GUIPI TANG etc.; The most frequently used Chinese medicine is followed successively by Radix Angelicae Sinensis, Poria, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Radix Bupleuri, Fructus Ligustri Lucidi, Radix Glycyrrhizae, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Semen Persicae, Herba Leonuri, the Radix Rehmanniae, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, the Radix Angelicae Dahuricae, Fructus Corni, Herba Leonuri, Rhizoma Dioscoreae, Fructus Ligustri Lucidi, Rhizoma Cyperi etc.But the effect of these Therapeutic Method is not very desirable, fundamentally can not treat chloasma, and also has certain side effect.Therefore, the medicine preventing and treating chloasma improving a kind of highly effective and safe has become the urgent needs of people.Prevalence is on the rise in recent years, gives much people's spirit of liking to be beautiful and in lifely cause great misery now.

About the treatment of butterfly spot, chloasma, Western medicine is cracking-off agent (as retinoic acid, salicylic acid), Donisolone, plumbous mercurial, oxidant or reducing agent (as hydroquinone, hydrogen peroxide) mainly, has side effect in various degree or causes some complication.

Summary of the invention

Technical problem to be solved by this invention is, at different age levels, people easily occur dissimilar speckle on the face.Common pigmented spots include: nevus fuscoceruleus ophthalmomaxillaris, freckle, sunburn, senile plaque.Pigmented spots are caused by a variety of factor: one is relevant with heredity, and some pigmented dermatosis of parents entails the next generation; Two is that endocrine disturbance causes pigmentation; Three is erratic living habit, and long stress causes cutaneous pigmentation; Four is cicatrixes that wound, acne etc. stay, and also can leave pigmentation.Vitamin C is oxidant, can suppress the Oxidation of DOPA quinone in skin, makes the dark oxidized form pigment in skin be converted into reduced form light color element, the formation of check melanin.Whitening and speckle dispelling is the life career of women, and investigation mission outside the city or town for oral administration has side effect in various degree or causes some complication; And oral medicinal herb medicine has some curative effects, but higher at drug manufacture cost, and also manufacturing cycle is longer, and preparation method is loaded down with trivial details; External used medicine specific aim is poor, and individual dispenser can not fundamentally treat chloasma, butterfly spot; And also have certain side effect.Therefore, find a kind for the treatment of butterfly spot of highly effective and safe, urgent needs that the medicine of chloasma has become people.

Face mask of traditional Chinese medicine external, except directly improving facial blood circulation, with the Chinese medicine such as the Radix Angelicae Dahuricae, Bombyx Batryticatus blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing.Give face mask of traditional Chinese medicine and directly act on skin, make it to absorb and reach the object of external treatment.Modern medicine study shows: tryrosinase is catalyst important in melanocyte production process, suppresses its activity then can control the generation of melanocyte, and the Pseudobulbus Bletillae (Rhizoma Bletillae) can the effect of restraint of tyrosinase and the enzymatic reaction of participation thereof; In addition, according to herbal pharmacology effect, the Radix Angelicae Dahuricae has antityrosinase active, stops oxidizing tyrosine to form pigment thus the effect having skin care crease-resistant.In addition the maneuver such as ionspray, massage can blood circulation promoting, expansion blood capillary, accelerate the infiltration of medicine and absorption, thus reach brighten, the effect of speckle dispelling.

For solving these technical barriers, the invention provides a kind of face mask of traditional Chinese medicine of skin care speckle removing of invigorating blood circulation, the crude drug of following parts by weight can be comprised: 10 ~ 50 parts, Flos Rosae Rugosae in facial film described in it, Radix Angelicae Sinensis 10 ~ 20 parts, Radix Rhodiolae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, Flos Albiziae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, Herba Leonuri 10 ~ 20 parts, Flos Pelargonii 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Ampelopsis 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Flos Rosae Chinensis 10 ~ 20 parts, common perilla 10 ~ 20 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts.

The face mask of traditional Chinese medicine of described skin care speckle removing of invigorating blood circulation, the crude drug of following parts by weight can also be comprised: 10 ~ 40 parts, Flos Rosae Rugosae in facial film described in it, Radix Angelicae Sinensis 10 ~ 15 parts, Radix Rhodiolae 10 ~ 15 parts, Rhizoma Chuanxiong 10 ~ 15 parts, the Radix Astragali 10 ~ 15 parts, Flos Albiziae 10 ~ 15 parts, Bombyx Batryticatus 10 ~ 15 parts, Herba Leonuri 10 ~ 15 parts, Flos Pelargonii 10 ~ 15 parts, Radix Saposhnikoviae 10 ~ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 15 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Ampelopsis 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Flos Rosae Chinensis 10 ~ 20 parts, common perilla 10 ~ 20 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts.

The face mask of traditional Chinese medicine of described skin care speckle removing of invigorating blood circulation, also the crude drug of following parts by weight can be comprised: 10 ~ 30 parts, Flos Rosae Rugosae in facial film described in it, Radix Angelicae Sinensis 10 ~ 20 parts, Radix Rhodiolae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, Flos Albiziae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, Herba Leonuri 10 ~ 20 parts, Flos Pelargonii 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 15 parts, Radix Ampelopsis 10 ~ 15 parts, Radix Angelicae Pubescentis 10 ~ 15 parts, the Radix Angelicae Dahuricae 10 ~ 15 parts, 10 ~ 15 parts, Flos Carthami, Flos Rosae Chinensis 10 ~ 15 parts, common perilla 10 ~ 15 parts, Fructus Atriplicis Sibiricae 10 ~ 15 parts.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of face mask of traditional Chinese medicine of skin care speckle removing of invigorating blood circulation, and it is characterized in that, the preparation method of described facial film comprises:

A, get Radix Rhodiolae, Radix Saposhnikoviae, common perilla and Pseudobulbus Bletillae (Rhizoma Bletillae) steam method and distill, obtain crystallization, for subsequent use as component 1;

B, the roseleaf alcohol extraction will gathered again are component 2;

C, all the other raw materials are added ethanol extraction 2 times, merge concentrated extracting solution, as component 3;

D, above-mentioned three kinds of components merge stirring, and the Cera Flava that is in harmonious proportion makes facial film, cold preservation after ultraviolet sterilization.

In described step a, first Radix Rhodiolae, Radix Saposhnikoviae, common perilla and Pseudobulbus Bletillae (Rhizoma Bletillae) steam method can be distilled according to described number, obtain crystal, cross 100-120 order dusting cover, for subsequent use as component 1.

In described step b, comprise the step of extraction, the chopping of the roseleaf of collection be placed in lid stainless steel cask, added 70% ethanol, quality is 0.8-1 times of coarse powder, and stir, moistening airtight placement more than 1 hour, makes abundant expansion; Drug sample after moistening expansion is mixed pine by filter plate gauze bag parcel again bottom percolator after paving does loose, then powder is contained with rustless steel spoon, uniform loading percolator, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitable pressurization, medicated powder must not load 2/3 eminence exceeding percolator; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, then slowly add 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, control percolation speed and be generally 1000g medical material outflow 2 ~ 3ml per minute, filtrate puts into liquid container, and pours ethanol time emptying into liquid container; Merged by percolate and leave standstill, heating is concentrated into paste, stand for standby use, becomes component 2.

In described step c, all the other raw materials can be added the soak with ethanol 4-6 hour accounting for its quality 5-10 times amount, heating extraction 2 times, each 1-2 hour, merge extractive liquid, supernatant is removed after leaving standstill, then 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.25 filtrate, leave standstill and put into economic benefits and social benefits vacuum concentrator and mix, when first filtrate being concentrated into 80 DEG C, relative density is the concentrated solution of 1.32, then inserts 0 ~ 5 DEG C of deepfreeze 24 hours; Cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g extractum, as component 3.

In described steps d, three kinds of component mixing above-mentioned steps can extracted, stir, heating, mediation substrate, and substrate selects propolis, ultraviolet sterilization bottling cold preservation.

The preparation method of the face mask of traditional Chinese medicine of described skin care speckle removing of invigorating blood circulation, it is propolis or Mel that the present invention is in harmonious proportion substrate used.

The using method of the face mask of traditional Chinese medicine of described skin care speckle removing of invigorating blood circulation, because facial film of the present invention is not containing antiseptic, necessary cold preservation, each just before going to bed after clean, by facial film uniform application in face, and by middle finger finger belly at face message 15-20 minute, after fully absorbing to it, wash away.

The present invention, in line with the therapeutic rules for the treatment of must aim at the pathogenesis of disease, controls from gas, stasis of blood opinion, holds concurrently with tonify deficiency righting.By vital energy regualting and blood circulation-promoting, adjust smooth QI and blood, dredging the meridian, hold concurrently with nourishing the liver and kidney, make human body adjust to lastingly, the state that stable equilibrium between yin and yang, QI and blood are unobstructed.Thus reach spot-removing beautifying face, beautify the object of appearance.The present invention, by vital energy regualting and blood circulation-promoting, adjusts smooth QI and blood, dredging the meridian, holds concurrently with nourishing the liver and kidney, makes human body adjust to lastingly, the state that stable equilibrium between yin and yang, QI and blood are unobstructed.Thus reach spot-removing beautifying face, blood circulation promoting and blood stasis dispelling, beautify the object of appearance.Blood-activating and qi-promoting of the present invention, treating chloasma and acne.For chloasma, the acne of caused by energy stagnation and blood stasis.Butterfly spot.External blood stasis dispelling, dispel the wind speckle removing.

Detailed description of the invention

Chloasma: also known as butterfly spot, chloasma hepaticum, presents filbert, and in the form of sheets, patch differs in size, sharpness of border, and out-of-shape does not exceed skin, is common in face, is symmetrical in two cheeks, and main cause is relevant with endocrine, estrogen imbalance.Chinese medicine is also referred to as chloasma hepaticum, also known as " chloasma ", betides the filbert or brown macules of face, be mainly in middle-aged women.Because the age of people increases, the fine circulation between histiocyte is by resistance of becoming silted up, and cytolysis is dead, and melanin increases and forms that mottle calmness causes, and is the pigmentation spots occurring in face.Long-term Oral contraceptive, suffers from women's also easy long chloasma of the disease such as pelvic inflammatory disease, hysteromyoma.

Freckle: 99% from heredity, formed between 5 ~ 6 years old greatly, the white people sent out in indigo plant are quite common, but Aisan is also found almost everywhere.The age occurred, the position that sun obtains produced the light brown speckle of size about 1 to 2nm, and its size, number and the pigment degree of depth increased the weight of in summer, took a turn for the better in the winter time at preadolescence.。

Sunburn: occur erythra erythema, the edematous condition such as visible, the sharp-edged erythema of naked eyes, pimple by shining skin, color is pale red, cerise or peony, present oval projections or level and smooth, finally become broken brown speckle after a couple of days, easily appear at outside forearm, on front side of the back of the hand, shank and the exposure portion such as face.

Cholasma uterinum (cyasma): occur when pregnancy, but just can decorporate in puerperal; The time formed due to black speck is very close with age time conceived, and therefore some people also can occur black speck while cholasma uterinum occurs, what therefore some people produced after takeing for conceived production is cholasma uterinum.

Hydrargyrum speckle: the skin of some people creates black speck; and be ignorant of protection how; some products that can bleach of hearsay; but whether these products do not contain the composition of hydrargyrum through chemical examination; although it can temporarily whitening; residual hydrargyrum and toxin but can make skin be subject to larger injury, even can hurt kidney.Hydrargyrum can be added in inside skin whitener by some bad manufacturer, and short time bleaching effect can clearly, if but life-time service, mercury element can Shen Dian in skin, to crack down upon evil forces and more black, the hydrargyrum speckle be namely commonly called as.

Tinea versicolor: tinea versicolor is quite common disease, is especially apt to occur in summer.In Dermatology Outpatient Department some sufferer normal, with for all erythra caused by sweat, be all tinea versicolor, this is incorrect in fact.Tinea versicolor is really easier to occur in sweat and smoulders place, similarly is neck, shirtfront, back, but it refers in particular to the erythra caused by a kind of fungal infection skin of yeast-like fungi sample.Typical tinea versicolor can show with the white of raindrop shape or coffee-like speckle.If sweat or heat time sometimes after affected part can be rubescent or itch suddenly, be its characteristic.

Mongolian oak: during birth, especially buttocks, lower back portion have nattier blue spot with it, just like bumping against " black green grass or young crops, congestion ", can disappear completely before usual four years old and taking off, not needing treatment.

Field mother's mark: the scope of this kind of melanocyte proliferation, upwards all may join together to the position of forehead from the corners of the mouth speckle of slaty, the overwhelming majority is one-sided, also has minority case bilateral to have, and the part that it is characterized by the sclera (white of the eye) of eyes also has navy blue speckle.May be very light during birth, can get more and more more dark.When some people is birth not, childhood, even adolescence just slowly produced.

Black speck: thinner, the more dry people of skin can be obvious, may be failure to maintain, sun-proof work does imperfect, and the top layer making melanin easily float to skin is caused, be the modal cosmetic problem of female middle-aged (male also can produce black speck but rarely found).Usually at two cheeks, forehead, upper lip and chin, the reddish brown brown speckle of whole piece is produced, because the relation of color is commonly called as chloasma hepaticum again.The factor of Producing reason and deterioration comprises: pregnancy, oral contraceptive, some drugs (as antuepileptic) and Exposure to Sunlight.Most people is just difficult to nature once generation and disappears and take off.Opsonizing method, comprises Tretinoin A, azelaic acid, hydroquinone, fruit acid, L-ascorbic acid, kojic acid etc., coordinates sun-proof measure thoroughly, can obtain goodish therapeutic effect.

Senile plaque: full name is " senile pigmented spots ", be medically otherwise known as seborrheic keratosis.Refer to a kind of lipofuscin pigment speckle occurred on old people's skin, belong to a kind of benign epidermic's hyperplastic tumours, generally have more present face, forehead, back, cervical region front etc., sometimes also may appear at the positions such as upper limb.Major part is after 50 years old, start length, and be more common in man at an advanced age, people are called again " senile plagues ".Modern medicine study result shows, this elegant name is had an undeserved reputation, the mark that it is not long-lived, and brainstrust finds, along with the growth of population mean age, senile plaque is not general in old people, only accounts for 27%.

Pathogen and pathology of tcm is analyzed: in the classical documents of the traditional Chinese medical science, have following discussion to the etiology and pathogenesis of primary disease." General Treatise on the Cause and Symptoms of Diseases " is said: " dark complexion person, or internal organs have phlegm retention, or skin is by ailment said due to cold or exposure, all makes qi and blood disorder, causes raw black.The vital organs of the human body 12 menses, all go up in face, the trip of husband's blood, all flourish the exterior and the interior.People or phlegm retention waterlogging possession, or space between skin and muscles wind-engaging hyperamization gas discord, puckery or turbid, can not be flourish in skin, therefore become raw black ".Golden Mirror of Medicine is said: " depressed by troubled thoughts, blood is weak not magnificent, and fiery dryness accumulated in the stomach and intestine is stagnant and be born on face, and women has it more." " surgery great achievement " say: " and chloasma is born in the face of woman more, weak not magnificent by blood, and fiery dryness accumulated in the stomach and intestine becomes, doubtful thing certainly caused by." " Waike Zhengzong, Orthodox Manual of External Diseases " say: " and chloasma person, water thanks to can not fire processed, blood are weak can not magnificent meat so that fiery dryness accumulated in the stomach and intestine spotting is black, and color is withered not damp." motherland's medical science thinks, this pathogenetic endogenous cause of ill with liver,spleen,kidney three is dirty and QI-blood circulation not normal in close relations, therefore treatment by oral administration of medicines internal organs many from liver spleen kidney by controlling, start with from nourshing blood and promoting blood circulation of regulating the flow of vital energy QI and blood is many; This pathogenetic exopathogenic factor is because of " space between skin and muscles wind-engaging hyperamization gas is got along well, puckery or turbid, can not be flourish in skin ", or " blood is weak not magnificent, and fiery dryness accumulated in the stomach and intestine becomes ", namely because blood deficiency or skin are supported by ailment said due to cold or exposure or not smooth the caused passages through which vital energy circulates mistake of QI-blood circulation.Therefore, external treatment should carry out prescription from the angle of promoting the circulation of blood wind dispelling of enriching blood.

Theory of Chinese medical science is thought " have Zhu Neibi shape all outer ", and " vital organs of the human body 12 are through QI and blood, all up in face." to stop in the generation of chloasma and human body depression of liver-QI, stagnation of blood stasis, caused by liver and kidney deficiency, insufficiency of vital energy and blood, expectorant are turbid etc. multiple because of Suo Youguan.Its pathogenesis or by depression of liver-QI, with the passing of time heat-transformation, fumigates and give birth in face; Or because of qi depression to blood stasis, battalion defends and becomes estranged, and stops up stagnant channels, ties and send out in face; Or because of Liver and kidney deficient, Chong and Ren channel disorder, asthenia of essence and blood, can not go up and flourish to form in face; Or be that insufficiency of the spleen mistake is good for, raw in phlegm-damp, turbid pathogen blocks and causes in face.It is clinical adopts the therapy approach such as treatment by oral administration of medicines, external treatment, acupuncture, massage more, lays particular emphasis on from liver,spleen,kidney and starts with, and it is disorderly to correct function, eliminates gas, the stasis of blood, expectorant, the pathological factor such as wet, hot.Conventional method for the treatment of has that dispersing the stagnated live-QI to relieve the stagnation of QI, vital energy regualting and blood circulation-promoting, nourishing the liver and kidney, soothing liver and strengthening spleen, warming YANG activating the spleen, dampness removing reduce phlegm, eliminating damp-heat etc.

Traditional Chinese medical science QI and blood theory is thought, qi-blood circulating process is the material base that all histoorgans of human body carry out work, QI-blood circulating regularly freely balances as expensive, if QI and blood is not smooth will produce blood stasis, blood stasis hinders in body, will cause the deterioration of qi-blood circulating further, cause more serious stasis of blood plug, therefore the traditional Chinese medical science take QI and blood as guiding principle, make it smooth balance by regulating qi and activating blood, can disease-relieving and physique enhancing, beauty treatment of nourishing blood.Skin speckle basic in the stasis of blood, move back speckle must first blood stasis dispelling, blood stasis dispelling when invigorating blood circulation, invigorate blood circulation more must QI invigorating, regulate the flow of vital energy, qi being the governor of blood, blood runs thereupon; Blood is keeping of gas, be so incensed that and quiet, depressed then blood clotting, the deficiency of vital energy then blood prostration, gas compel then blood walk.QI and blood and then all and.And regulate the flow of vital energy liver, QI invigorating at lung kidney, lung governing skin and hair.Because of qi depression to blood stasis, have influence on the QI-blood circulation function of lung spleen Liver and kidney, and cause face and occur the mottle such as chloasma, freckle, even occur alopecia, alopecia areata.The present invention mainly identifies and corrects the principle treated according to Chinese medicine, collect many doctor chiefs, extensively adopts the strange medicine wonderful recipe in rich receipts area, skims the cream off milk; Based on Chinese medicine to pathogenetic understanding of facial colour spot and Therapeutic Principle, reference is Chinese medicine pharmacological research achievement at all times, the natural Chinese medicine of screening inrigorating qi and promoting blood circulation, tonifying Qi and lifting yang, dispersing the stagnated live-QI to relieve the stagnation of QI, suppressing the hyperactive liver and subsiding YANG, enriching yin and nourishing kidney, heat-clearing and toxic substances removing, clearing away heat-fire, strengthening vital QI to eliminate pathogenic factors, purging FU-organs lets out poison, promoting blood circulation to remove blood stasis, regulates the metabolism function of human body, improve blood circulation of human body and liver detoxification ability, and form through the clinical practice summary of long-term diagnosis and treatment case.

Primary disease is called " chloasma ", " chloasma hepaticum ", " dusty face " etc. by motherland's medical science.Occur in the classical documents of the traditional Chinese medical science due to primary disease, have following discussion to the etiology and pathogenesis of primary disease." General Treatise on the Cause and Symptoms of Diseases " is said: " dark complexion person, or internal organs have phlegm retention, or skin is by ailment said due to cold or exposure, all makes qi and blood disorder, causes raw black.The vital organs of the human body 12 menses, all go up in face, the trip of husband's blood, all flourish the exterior and the interior.People or phlegm retention waterlogging possession, or space between skin and muscles wind-engaging hyperamization gas discord, puckery or turbid, can not be flourish in skin, therefore become raw black ".Golden Mirror of Medicine is said: " depressed by troubled thoughts, blood is weak not magnificent, and fiery dryness accumulated in the stomach and intestine is stagnant and be born on face, and women has it more." " surgery great achievement " say: " and chloasma is born in the face of woman more, weak not magnificent by blood, and fiery dryness accumulated in the stomach and intestine becomes, doubtful thing certainly caused by." " Waike Zhengzong, Orthodox Manual of External Diseases " say: " and chloasma person, water thanks to can not fire processed, blood are weak can not magnificent meat so that fiery dryness accumulated in the stomach and intestine spotting is black, and color is withered not damp." motherland's medical science thinks; this pathogenetic endogenous cause of ill is with liver,spleen,kidney three is dirty and QI-blood circulation not normal in close relations; therefore treatment by oral administration of medicines is controlled from liver spleen kidney opinion internal organs are many, although be in the skin lesion on skin of face surface in gas chloasma, is also the external reflection of body interior dysequilibrium.So will from entirety in treatment, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Liver spleen essence and blood is full, punching appoints tune smooth, then the money of medicine carrying had by oneself by blood network.Liver controlling conveyance and dispersion, can adjust and reach QI and blood, happy feelings will.If depression of liver-QI, qi-blood disharmony. qi depression to blood stasis. stop up stagnant channels, on tie and then cause speckle in face.Liver storing blood.Liver blood fill and, then body be good for face profit.If deficiency of the liver and kindey, blood and essence asthenia, can not go up Rong Ze easily raw speckle.

The Radix Astragali, can invigorating QI to consolidate the body surface resistance based on tonify deficiency, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Cave in for insufficiency of vital energy and blood, skin infection, difficulty in discharging of pus or burst for a long time and do not hold back person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration strengthening, i.e. the abscess suppuration granulation promoting of disunion for a long time.Modern medicine study shows, the Radix Astragali includes and multiple antibiotic effective ingredient, and the immunologic function of energy enhancing body, therefore can also be used for the generation preventing some infectious disease." book on Chinese herbal medicine meets former " carries: " all void of Radix Astragali energy tonifying five ZANG-organs, controls stringy pulse spontaneous perspiration, rush down YIN-fire, remove lung-heat, lossless, sends out, and has antiperspirant then to stop." be the good medicine promoting resistance and defence disease.

Radix Angelicae Sinensis: its sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, and invigorating middle warmer has, has benefit, the gas medicine in sincere blood, the panacea also in blood in row.Then mending to mend of about assistant, therefore can nutrition blood be supported, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, unsuitable without institute.Assistant to attack, lead to, therefore pain relieving constipation of dispelling, relieving rigidity of muscles and joints, controls contracture, paralysis, the card such as dry, puckery.Nutrient QI being deficient and exterior syndrome being not relieved person, help with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, and can fall apart greatly Biao Weire, and show not hold back person, helps with Radix Et Rhizoma Rhei and so on, again can consolidating superficial resistance.Precisely because gas Xin Erdong, therefore for its quiet person when keeping away it, the sliding benefaction of property, stool does not consolidate person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, and cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.

Rhizoma Chuanxiong is pungent, temperature.Return liver, gallbladder, pericardium channel.Function blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Rhizoma Chuanxiong is warm in nature, is gynecological's common drug, has the effect of activating blood cirulation to regulate QI flow, but can not be multiplex, and especially health has the people of bleeding to be not suitable for taking, as female menstrual period.Meanwhile, Rhizoma Chuanxiong is again one of medical material conventional in medicated diet, with Gallus Domesticus with eating, can nourishing yin and activating blood, and be women's excellent tonic product.

Flos Pelargonii, Classification system: Pelargoniumhortorum, has hemostasis, vasoconstrictive, asthma, liver and expelling toxin, cholelithiasis, kidney toxin expelling, renal calculus, diuresis, muscular soreness, oily skin, aging skin activates, herpes, palor, fat-reducing, promotes to scab, eczema, sunburn of burning, tinea, menstruation has some setbacks, engorgement of breasts inflammation, alleviates melancholy uneasy, drives demon, mend body, deodorization, antibacterial, sterilization, smoking cessation (wine).The major function of Flos Pelargonii is to adjust skin, and the effective ingredient in Flos Pelargonii extracting solution and natural alicyclic organic have very strong affinity, and therefore, the normal combination with alicyclic organic of Flos Pelargonii makes lipoid product.General cleaning supplies are after cleaned, the functional components major part of skin protection can be rinsed by water and be run off, the scientific research personnel of Switzerland is on the basis of three-hypers fresh extractor technology, select to hands sections such as organized enzymes by adding, the effective ingredient of Flos Pelargonii is made also to produce affinity with skin epidermal area while affine with lipoid, this affinity has surmounted the affinity with water, therefore, in the process of cleaning, most of effective ingredient of Flos Pelargonii still can be absorbed by the skin, play the effect adjusting skin, Flos Pelargonii is almost applicable to various skin, because it can balance sebum secretion and make turgor.May to eczema, burn, herpes zoster, herpes, tinea and chilblain be useful.Slack and undisciplined, pore is blocked and oily skin also fine, because Flos Pelargonii can pore refining, blood circulation promoting, can allow after using pale skin is comparatively ruddy vigor, makes the glossy exquisiteness of skin.

Radix Rhodiolae, Chinese medicine name.For the dry root welding technology of Crassulaceae Radix Rhodiolae, autumn scape withered after excavate, removing rough bark, clean, dry.Sweet in the mouth, hardship, property is put down, and returns lung, heart channel.There is benefiting QI for activating blood circulation, the merit of relievining asthma of promoting blood circulation.Be mainly used in blood stasis due to qi deficiency, obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, asthenia is panted." Chinese medicine voluminous dictionary " is recorded: and Radix Rhodiolae " cold in nature, sweet-puckery flavor.Promoting blood circulation and hemostasis, clearing away lung-heat to relieve cough.Control hemoptysis, spitting of blood, pneumonia is coughed.

Herba Leonuri acrid in the mouth is bitter, cool.Invigorate blood circulation, silt of dispelling, regulating menstruation, disappear water.Treatment menoxenia, vaginal bleeding during pregnancy is had difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, and metrorrhagia and metrostaxis, rushes down blood, carbuncle skin infection at hematuria.Herba Leonuri, containing the material such as leonurine, Fumaric acid, has the effects such as promoting blood flow to regulate menstruation, blood pressure lowering, inducing diuresis to remove edema.

Flos Albiziae contains Herba Albiziae glycoside, tannin, resolving stagnation for tranquilization, appetizing of regulating the flow of vital energy, activating collaterals to relieve pain, for irritability, melancholy insomnia.Control pent-up uncomfortable in chest, insomnia, forgetful, acute conjunctivitis, can settling five organs, and will, improving healthy complexion, have keep fit preferably, calm, the effect of calming the nerves, improve looks, be also treat neurasthenic good merchantable brand.Also have clearing away summer-heat, face-beautifying and spot-removing such as to relieve the effect of alcohol at the effect." herbal warp " is said: " Flos Albiziae energy settling five organs, and will, improving healthy complexion." especially to anemia of pregnant woman, have keep fit preferably, calm, the effect of calming the nerves, improve looks, be also treat neurasthenic good merchantable brand.

The Radix Paeoniae Alba enters liver, spleen channel, nourishing blood to suppress the hyperactive liver, pain relieving in slow, and yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, and spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia, married woman's blood closes obstructed, repercussive blood, can lose pus, beneficial woman's blood." Japan hanako materia medica ": control wind, mend labor, all diseases of main woman, and antenatal rear all diseases, Tong Yueshui, brings down a fever, relieving restlessness, QI invigorating, the capable hot disease in sky, pestilence miasma, mania and irritation, and married woman's blood is transported, and hemorrhoidal hamorrhage, rushes down blood, hemorrhoid complicated by anal fistula.Carbuncle on the back, skin ulcer scabies, headache, improving eyesight, conjunctival congestion exerts meat.The many QI invigorating of redness of the skin or complexion person, white person controls blood.

Pseudobulbus Bletillae (Rhizoma Bletillae) property is bitter, sweet, puckery, is slightly cold.Return lung, liver, stomach warp.Function cures mainly astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.Shennong's Herbal: " main carbuncle, malignant boil, lose cellulitis, the dead flesh of impairment of YIN, pathogen in stomach "; Compendium of Material Medica: " abnormal smells from the patient (root) is bitter, flat, nontoxic.

Radix Angelicae Dahuricae meridian distribution of property and flavor: pungent, temperature.Attach to the lung and stomach meridians.Expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping." Japan hanako materia medica ": control conjunctival congestion bulbar conjunctiva polyp, and tire patching leaks landing, broken stagnated blood, mend fresh blood, acute mastitis, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, evacuation of pus, desolation, scabies, pain relieving granulation promoting, goes face Shao-defect scar.

Bombyx Batryticatus enters liver, lung, stomach warp.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Control apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble.Sore throat, scrofula tuberculosis.Wind skin ulcer urticaria, erysipelas, mastitis." herbal classic ": main pediatric epilepsy scared night cry, goes three worms, Mie Hei über, and the cloudy infections of man is sick." not Lu ": woman's metrorrhagia is in vain red, puerperal remaining pain, all skin ulcer cicatrixs of going out.Not it, envelope furuncle swell, root ought go out certainly." property of medicine opinion ": control locked mouth, diaphoresis, housewife people's metrorrhagia hematochezia is more than.

Radix Ampelopsis returns through heart channel; Lung meridian; Liver Channel; Spleen channel.Function: heat-clearing and toxic substances removing; Removing obstruction for relieving pain; Promoting tissue regeneration and ulcer healing.Cure mainly: sore swollen toxin, scrofula, scald, eczema, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula, leucorrhea, traumatic injury, traumatic hemorrhage.Radix Ampelopsis is the root of vitaceae Radix Ampelopsis, and annual spring, autumn excavate, and removing stem and thin fibrous root, after cleaning, many rip cuttings become two lobes, pintongs or inclined tab, dry and can be used as medicine.It is cool in nature, and bitter but sweet flavor is pungent, has effect of heat clearing away, removing toxic substances, eliminating stagnation, granulation promoting, pain relieving, is used for the treatment of the diseases such as carbuncle, furuncle, scrofula, scald, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula

Flos Rosae Rugosae: road in " herbal text ": " Flos Rosae Rugosae, turbid clearly and not, and and not violent; easing the affected liver is waken up stomach, and thin gas is invigorated blood circulation, and a surname is logical stops up stagnant and absolutely not pungent temperature is just dry fraud; disconnectedly push away among edema caused by disorder of QI medicine, has prompt effect and the most tractable, fragrant all product; there is no equal most " in Flos Rosae Rugosae containing 300 various chemical components, as the alcohol of fragrance, aldehyde, fatty acid, phenol and containing the oil of essence and fat, to wake up stomach with easing the affected liver in normal food Flos Rosae Rugosae goods, have a respite and invigorate blood circulation, looks improving and the skin nourishing, makes us refreshing refreshing.The flower opened at the beginning of Flos Rosae Rugosae and root can be used as medicine, and regulate the flow of vital energy, invigorate blood circulation, Thyme Extract, cure mainly menoxenia, and traumatic injury, irritability are had a stomachache, the diseases such as newborn too fat to move pain.The sarcocarp of Rosehips, can be made into fruit jam, has flavour, and fruit contains abundant vitamin C and Citrin, and acute and chronic infectious disease, coronary heart disease, hepatopathy and prevention can be prevented to produce carcinogen etc.With the Flos Rosae Rugosae quintessence oil (title Liquor Rosae Rugosae Distillata) that roseleaf obtains with way of distillation refinement, androgen and sperm can be activated.Liquor Rosae Rugosae Distillata can also improve skin texture, blood circulation promoting and metabolism.

Flos Rosae Chinensis, Chinese medicine name.For the dried floral of rosaceous plant Chinese rose RosachinensisJacq..The whole year all can gather, and plucks, dry in the shade or cold drying when spending crack.Be cultivation.There is promoting blood flow to regulate menstruation, effect of dispersing the stagnated live-QI to relieve the stagnation of QI.Be usually used in qi depression to blood stasis, menoxenia, dysmenorrhea, amenorrhea, distending pain in the chest and hypochondrium.

Radix Angelicae Pubescentis, Chinese medicine name.For the dry root of samphire Angelica pubescens.Main product in Sichuan, Hubei, the ground such as Anhui.At the beginning of spring or autumn end excavate, removing fibrous root and silt, a heatable brick bed, to half-dried, is banked up 2 ~ 3 days, after feeling like jelly again a heatable brick bed to absolutely dry.Section, raw use." book on Chinese herbal medicine just ": " specially reason part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels rheumatism, two pain in foot numbness, pruritus due to damp pathogen contracture." modern study, Radix Angelicae Pubescentis has antiinflammatory, analgesia and sedation; Inhibitory action is had to platelet aggregation; And it is not have hypotensive effect, but lasting; Contained bergapten, xanthotoxin etc. have photosensitive and antitumor action.

Common perilla: Latin literary fame FoliumPerillaeFrutescentisPerillaeFoliumPerillaeFrutesce ntis, cures mainly cold; Cough and asthma; Gastral cavity abdominal distention is vexed; Accumulation of food in the stomach and intes tine due to indigestion; Vomit and diarrhoea; Cold-dysentery; Middle fish Eriocheir sinensis poison; Man's swelling of the vulva; Limb edema due to disorder of QI poison; Snake bite and insect sting." Japan hanako materia medica ": regulating QI, profit cardiopulmonary, longue skin, beneficial color, disappear dyspepsia, only upper gas cough, and go bromhidrosis, deposited Serpentis stings." the southern regions of the Yunnan Province book on Chinese herbal medicine ": cure the wound cold heating, lossless, headache, and all wind and cold expectorant gush and tie, cramp caused by acute vomiting and diarrhea, and cough is spat, little eclampsia disease.Analgesic therapy, Zhichuan.

Fructus Atriplicis Sibiricae is the mature fruit of the annual or herbaceos perennial Fructus Tribuli Tribuluster-restrisL. of zygophyllaceae.Whole nation most area is all produced, but more with North of Yangtze River.Bitter, pungent, flat, enter Liver Channel.Function effect suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.

Radix Saposhnikoviae, Chinese medicine name.Another name copper rue, Hui Yun, return grass, Rhizoma Cibotii, hundred kinds.The name of a kind of medicinal herbs, herbaceos perennial, the nice and cool weather of its happiness, cold-resistant, drought-resistant, main product in Hebei, Heilungkiang, Sichuan, the ground such as Inner Mongol.The Gen Kesheng of Radix Saposhnikoviae uses.Acrid in the mouth, sweet, slightly warm in nature.There is expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.Compendium of Material Medica: " wind as 36, goes part of the body cavity above the diaphragm housing the heart and lungs ailment said due to cold or exposure, the stagnant gas of the head, and meridians stay wet, all over the body pain all over the joints.Except wind dries elixir." " medicine class on the analogy of natural things ": " control wind general.Eliminating the pathogens from the lung is real, stagnant gas in the loose head, except the part of the body cavity above the diaphragm housing the heart and lungs is evil.”

The Rhizoma Atractylodis Macrocephalae (zh ú), Classification system Atractylodesmacrocephala.Another name small wooden raft Ji, Rhizoma Atractylodis Macrocephalae, the winter Rhizoma Atractylodis Macrocephalae, wash rice art, poplar small wooden raft, Wu Shu, sheet art, Rhizoma Atractylodis etc., belong to Compositae, [WTBX herbaceos perennial.The nice and cool weather of happiness, is used as medicine with rhizome, has multinomial medicinal function.Mainly be distributed in the mountain area wetlands such as Sichuan, Yunnan, Guizhou.The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, and for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement." medicine origin " is recorded: " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, go in taste wet, except gastric heat, strong taste, enter diet, antiabortive.”

Specific embodiment 1

Preparation of the present invention: Xia Qiu gathers roseleaf, and dry preparation, steeps into alcohol extraction, as component 1;

Get Radix Rhodiolae, common perilla, Radix Saposhnikoviae, the Pseudobulbus Bletillae (Rhizoma Bletillae) way of distillation be vaporized into crystallization, pulverize dusting cover stand-by, as component 2;

By all the other raw material Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Radix Astragali, Flos Albiziae, Bombyx Batryticatus, Herba Leonuri, Flos Pelargonii, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Ampelopsis, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Flos Carthami, Flos Rosae Chinensis, Fructus Atriplicis Sibiricae ethanol extraction 2 times, merges concentrated extracting solution, as component 3;

Component 1, component 2 are added substrate propolis after mixing with component 3 or Mel is in harmonious proportion, ultraviolet sterilization tinning, the present invention, must cold preservation not containing antiseptic.

Specific embodiment 2

Get Radix Rhodiolae 1000g, common perilla 1000g, Radix Saposhnikoviae 1000g, the Pseudobulbus Bletillae (Rhizoma Bletillae) 1000g way of distillation be vaporized into crystallization, pulverize dusting cover stand-by, as component 1.

The roseleaf 1000g of collection chopping be placed in lid stainless steel cask, added 70% ethanol, quality is 0.8-1 times of coarse powder, and stir, moistening airtight placement more than 1 hour, makes abundant expansion; Drug sample after moistening expansion is mixed pine by filter plate gauze bag parcel again bottom percolator after paving does loose, then powder is contained with rustless steel spoon, uniform loading percolator, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitable pressurization, medicated powder must not load 2/3 eminence exceeding percolator; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, then slowly add 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, control percolation speed and be generally 1000g medical material outflow 2 ~ 3ml per minute, filtrate puts into liquid container, and pours ethanol time emptying into liquid container; Merged by percolate and leave standstill, heating is concentrated into paste, stand for standby use, becomes component 2.

By all the other raw material Radix Angelicae Sinensis 1000g, Rhizoma Chuanxiong 1000g, Radix Astragali 1000g, Flos Albiziae 1000g, Bombyx Batryticatus 1000g, Herba Leonuri 1000g, Flos Pelargonii 1000g, Rhizoma Atractylodis Macrocephalae 1000g, Radix Paeoniae Alba 1000g, Radix Ampelopsis 1000g, Radix Angelicae Pubescentis 1000g, Radix Angelicae Dahuricae 1000g, Flos Carthami 1000g, Flos Rosae Chinensis 1000g, Fructus Atriplicis Sibiricae 1000g, adds 10 times amount ethanol extractions, heating and refluxing extraction 2 times, each 1 ~ 2 hour, 2 extracting solution are merged and leaves standstill, become component 2.By the merging of component 1 and component 2, then put into concentrating under reduced pressure tank, decompression recycling ethanol, being concentrated into liquor strength is 0.6g crude drug/mL, when sucking filtration to the relative density of filtrate is 20 DEG C 1.06; Above-mentioned filtrate is after the macroporous adsorptive resins absorption that volume is 10L, and with deionized water or the distilled water eluting of 10 times of resin column volumes, then use 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove solvent, obtaining concentrated solution, is component 3.

Component 1, component 2 are added substrate propolis after mixing with component 3 or Mel is in harmonious proportion, ultraviolet sterilization tinning, because the present invention is not containing antiseptic, so must cold preservation.

Specific embodiment 3

The manufacturing process of face film agent of the present invention is: first Radix Rhodiolae 1300g, common perilla 1200g, Radix Saposhnikoviae 1200g and Pseudobulbus Bletillae (Rhizoma Bletillae) 1300g steam method are distilled according to described number, obtain crystal, for subsequent use as component 1, get the medicinal residues mixing surplus stock Radix Angelicae Sinensis 1400g after distillation, Rhizoma Chuanxiong 1300g, Radix Astragali 1200g, Flos Albiziae 1300g, Bombyx Batryticatus 1300g, Herba Leonuri 1300g, Flos Pelargonii 1200g, Rhizoma Atractylodis Macrocephalae 1200g, Radix Paeoniae Alba 1300g, Radix Ampelopsis 1200g, Radix Angelicae Pubescentis 1300g, Radix Angelicae Dahuricae 1200g, Flos Carthami 1300g, Flos Rosae Chinensis 1300g, Fructus Atriplicis Sibiricae 1300g, add the 60-90% soak with ethanol 1-2 hour of 5-10 times amount, heating extraction 2 times, each 1-2 hour, remove supernatant, merge extractive liquid, 80-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.36 extractum, heating is concentrated, 30 minutes ~ 45 minutes, concentrated solution is settled into extractum shape, mass continues heating and is concentrated into extractum shape, stand for standby use, become component 2, the component 1 of distillation extraction and the component 2 of ethanol extraction are mixed, mixing Cera Flava, ultraviolet sterilization is bottled.Because the present invention is not containing antiseptic, so must cold preservation.

Pharmacological toxicity is tested

Toxicology test:

Test example 1: acute toxicity test of the present invention

One, test material:

Animal: Kunming mouse, body weight 21-24g, male and female half and half, Shandong University's biology laboratory breeding.Medicine: cosmetic cream of the present invention.

Two, method:

1, LD50 calculates: adopt improvement karber's method, mice is divided into 5 groups at random, often organize 10, male and female half and half, dissolve lotion, are made into Cmax, by the administration of mice maximum permission capacity, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml, observes animal dead situation.

2, maximum tolerated dose measures (MTD value): get mice 20, each 10 of male and female.Tablet adding distil water is dissolved, is made into maximum concentration, by the maximum tolerated dose of animal, feed device and can twitch to inject to fill with and be as the criterion.In animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml (every ml containing crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption.Continuous Observation 7 days after administration.

Three, result of the test:

In LD50 calculates when giving mice with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, namely LD50 is not measured, ask maximum tolerated dose only, in 7 day observation period, its appetite of animal, activity, hair color, the mental status etc. are all normal, grow normal, there are no death.Namely select the 300 times of doses being equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD > 18g/Kg.d.

Test example 2: acute skin irritation test report of the present invention

1, experiment purpose: detect the present invention to the stimulation/corrosiveness of laboratory animal skin and intensity

2, materials and methods:

2.1. tested material title: cosmetic cream of the present invention (embodiment method 2 obtains)

2.2. laboratory animal: one grade of large ear white race rabbit, 10, female, body weight 2.1-2.3kg; Thered is provided by Affiliated Hospital of Qingdao University biology department Experimental Animal Center;

2.3. test method:

Its spinal column both sides, back are cut by hair in test by the healthy rabbits selecting skin intact 10 for first 24 hours, the left and right each about 4cm × 4cm of unhairing area.Get tested material 0.2ml during test to be applied on two layers of gauze of 2.5cm × 2.5cm, be applied to skin of unhairing surface, side, oilpaper covers, immobilization with adhesive tape.Opposite side skin is as blank.Close after 4 hours, dismantle, and go residual tested material with warm water cleaning, within 1,24 and 48 hour after removing tested material, observe and smear position dermoreaction, and mark.

3, experimental result: any erythema does not appear in laboratory animal skin, red and swollen, inflammation phenomenon.

4, brief summary: judge according to skin wound repair standards of grading in " disinfection technology standard " (1999), ointment of the present invention belongs to nonirritant to animal skin stimulus intensity.

Embodiment 3: vaginal mucomembranous irritant test result

1. test method:

After laboratory animal is quarantined 3 days, select 18 above-mentioned healthy rabbits, be divided into three groups at random, often organize each 6, be respectively: blank, excipient control, eye cream of the present invention.Be placed in excipient control group and the intravaginal of tested material treated animal with the sterilizing cotton sliver leaching of suitable size with sterile saline and tested material respectively, contact 6 hours with vaginal mucosa, after 24 hours, put to death animal.Taking-up topical vaginal tissue, observes pathological changes situation.

2, result of the test: vaginal mucomembranous irritant test result

Embodiment 4: skin anaphylactic test result

Use cosmetic cream of the present invention, carry out inducing and exciting contact test, viewing test mice after 24 hours and 48 hours, all loseing skin has the phenomenon such as erythema and edema, with negative control group zero difference.Result shows, this unguentum is bordering on zero, namely without skin allergic reaction to dermoreaction intensity.

Embodiment 5: long term toxicity test data

1, experimental technique

Random for Cavia porcellus part is become 4 groups, often organizes 15.In guinea pig back spinal column both sides, depilatory is evenly coated, make its scope about 40 square centimeters of losing hair or feathers.Clean depilatory, observe and often organize Cavia porcellus after 24 hours and be coated with eye cream 0.2,0.4 of the present invention and 0.8ml respectively, respectively containing crude drug 92,184 and 368mg, another group is coated with the every twice-daily of solvent 0.8ml, continuous 30 days, observe the ordinary circumstance of Cavia porcellus, experiment terminates rear execution animal and carries out hematology, blood biochemical and pathological examination.

2, result

Above-mentioned three groups of medication Cavia porcellus trunk unhairing districts, having no local skin has edema, hyperemia, erythema, petechia and ulcer.Medication group and control animals chroma of hair, ingest, the matched group no significant difference such as extremity are movable, blood biochemistry checking, medication group and matched group are all in normal range.Histopathologic examination, tests each group of heart, liver, kidney and local skin and is showed no obvious pathological changes.Prompting, Chinese medicine facial cream long-term prescription of the present invention is showed no obvious toxic action to local skin and whole body important organ.

Pharmacological experiment illustrates:

1 material

1.1 animals: healthy 3 monthly age pure lines Kunming kind female mice 60, body weight 25 ~ 35g, the laboratory animal department of the Chinese Academy of Sciences of Shandong University provides.Animal feeding condition: often organize mice by group sub-cage rearing.When natural conditions are identical, routine raises food drinking-water, keeps natural lighting, without undesirable element impact, raises after within 1 week, adapting to experimental situation and starts to test,

1.2 experimental drugs: facial film of the present invention, by the preparation of embodiment 2 method, concentration: 0.12mg/ml, Pharmacy department of the court produces.3% Hydrochinone Cream: Pharmacy department of Wuhan Hospital of Traditional Chinese Medicine produces, lot number 20050905.Progesterone injection: Zhejiang Province XianJu Pharmacy stock Co., Ltd, lot number: 20050115.

1.3 reagent: sodium sulfide (NaS): the limited public affairs of extra large Ling Feng chemical reagent can, lot number: 20020118, is made into 10% aqueous solution before use.Superoxide dismutase (SOD), malonaldehyde (MDA) test kit: Bioengineering Research Institute is built up in Nanjing, lot number: 20059116.

1.4 key instruments: DY89-II type electric driven glass refiner: Xin Lan biotech inc, Ningbo.System biological microscope: OLYMPUS; BX50F4 Beijing Institute of Aeronautics Pathologic image analysis system.

2 experimental techniques

2.1 modellings: with reference to chloasma experimental animal model clone method.After the anesthesia of mice 2.5% pentobarbital sodium, the progesterone injection with 0.4% presses the intramuscular injection of 0.02g/kg dosage mouse hind leg, 6 times weekly, continuous 4 weeks.Normal group presses 0.02g/kg intramuscular injection sterilized water for injection.

2.2 animal grouping and administrations: get Healthy female mice 60,3 dosage groups, are divided into 6 groups at random, often organize 10.Normal group, model group, capsule of the present invention 3 dosage groups (0.15,0.3,0.6mg/ml), 3% hydroquinone positive controls (0.6mg/ml).The present invention's 3 dosage treatment groups respectively in mice modeling medication on the same day, every day 2 times, 6 times weekly, continuous use 30 days.Normal group and model group give distilled water in the corresponding time; 3% hydroquinone positive drug control group started local application in modeling the same day, and time and the course for the treatment of are with spot-removing beautifying face oral liquid treatment group.

2.3 observation index and detection: medication is after 30 days, and cervical dislocation puts to death mice, back unhairing, get rapidly each 2 pieces of the skin histology at hepatic tissue and coating position, wherein one piece with ice-cold normal saline flushing, removing blood, and filter paper blots, cut liver and each 0.5g of skin, put into the beaker of the pre-cold saline of 2.0ml respectively, shred tissue, then pour in test tube, with high speed disperser 10r/min homogenate twice, each 10 seconds; With 3500r/min rotating speed centrifugal 15 minutes again, get supernatant.Adopt xanthine oxidase, detect description method by test kit and measure SOD; Adopt thiobarbituricacidα-method, detect description method by test kit and measure MDA value.Meanwhile, separating mouse skin of back, get plucked skin histology one piece (about 2cm*1cm), 10% paraformaldehyde is fixed, routine paraffin wax embeds, section, and HE dyes, routine histopathologic detects, om observation, counting epithelial proliferation, dermal vascular number and chorionitis cell number; Immunohistochemical staining, (positive cell: nothing, counts 0 point for the dyeing of observation melanocyte and number; < 15%, counts 0.5 point, < 30%, counts 1 point; > 30% 2 points).

2.4 statistical methods: compare t inspection between measurement data employing group; Layered method data adopts rank test to carry out statistical disposition.

3 results

3.1 respectively organize mouse skin, hepatic tissue MDA, SOD content mensuration in table 1.

The mensuration (-x ± s) of mouse skin and hepatic tissue MDA, SOD content respectively organized by table 1

* P < 0.05, * * P < 0.01 is compared with model group; #**P < 0.05 is compared with positive group

3.2 respectively group mouse skin Pathomorphologics and immunohistochemistry views PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM visible: the epithelial layer cell arrangement of normal group mouse skin is neat, and without hypertrophy, have no thin vessels in skin corium and expand, inflammatory cell is rare.The epithelial layer hyperplasia of model group mouse skin is obvious, and the large and arrangement disorder of core, visible thin vessels expansion in skin corium, inflammatory cell is common.The epithelial layer hyperplasia of dosage group big or middle and positive controls mouse skin alleviates to some extent, and arrangement disorder alleviates, and in skin corium, thin vessels expansion alleviates, and inflammatory cell is rare.The results are shown in Table 2.

Immunohistochemical PATHOMORPHOLOGICAL OBSERVATION OF PULLORUM is visible: visible a little melanocyte in normal group mouse epithelial layer, the painted sepia of endochylema.Visible a large amount of melanocyte in model group mouse epithelial layer, the painted dark brown of endochylema, and positive cell number > 30%.Visible black color element cell in dosage group big or middle and positive controls mouse epithelial layer, the painted dark brown of endochylema, positive cell number reduces, in table 2.

Table 2 is group mice skin tissue pathomorphology and melanocyte observed result (n) respectively

Rank test; * P < 0.05, * * P < 0.01 is compared with model group

4, the microcirculation experimental technique of topical agent:

4.1 materials and methods: get 50 mices, be divided into 5 groups at random, often organize 10 (male and female half and half), and it is a little that matched group every Mus auris dextra is coated with normal saline; Positive controls every Mus auris dextra gives the white speckle dispelling ointment of commercially available silk (production of Nanjing Pharmaceutical), and test component is facial film dosage group 400mg/kg/h of the present invention, facial film 600mg/kg/h of the present invention, facial film high dose 800mg/kg/h of the present invention.15min pneumoretroperitoneum injects 0.1% pentobarbital sodium 0.1ml/10g anesthetized animal, subsequently tail vein injection 0.1% epinephrine 0.1mL/10g, observes mouse right ear fine motion vein bore (μm) and 0.2mm immediately ²blood capillary net number .t checks process experimental data.

4.2 results and discussion

4.2.1. on microcirculatory impact

Compared with matched group, tested group 1 pair mice capillary open number has showed increased (P < 0.01); Tested group of 2 pairs of venule bores and capillary open number have remarkable increase (P < 0.01); Tested group of 3 pairs of mice fine motions, vein bore and capillary open number all have increase (P < 0.01); Illustrate and be subject to reagent to improve microcirculation, have function of promoting blood circulation to disperse blood clots (table 1).

Table 3, externally used paste of the present invention are on the impact of mice fine motion, vein bore and capillary open number

4 discuss

The chloasma traditional Chinese medical science is called " chloasma hepaticum ", belongs to motherland's medical science " dark speckle " or " dusty face " category.It is generally acknowledged that primary disease occurs with liver,spleen,kidney three dirty in close relations.

Chloasma, chloasma hepaticum are a kind of dyskinetic dermatosis of metabolism of pigment being common in face, and be apt to occur in female middle-aged, its cause of disease and pathogeny are illustrated not yet completely.It is generally acknowledged morbidity and the endocrine disturbance of chloasma, ultraviolet radiation, inherited genetic factors is relevant.But research is in recent years thought, the generation of chloasma, chloasma hepaticum also changes relevant with oxygen-derived free radicals.Under normal physiological conditions, free radical constantly produces, but is also constantly eliminated, and makes it to be in a kind of dynamic equilibrium.And chloasma, chloasma hepaticum patient lipid peroxide (LPO) or Free Radical Level increases time, or antioxidase is as declines such as superoxide dismutase (SOD), catalase (CAT), glutathion (CSH) in body, the oxidation products such as lipid peroxide can not be removed in time, LPO is piled up in vivo.Thus accelerate the reaction of tyrosine series of oxidation.Blackening pigment cell produces melanin and increases; Its product malonaldehyde (MDA) of LPO extremely unstable can cause protein molecule to occur to be cross-linked simultaneously, forms fluorescent chromophore-pigment.

Thus point out the present invention can scavenging activated oxygen and reduce free radical produce; Pathologic examination shows it can obviously improve histiocytic pathological change, alleviates epithelial hyperplasia, alleviates the expansion of skin corium thin vessels, reduces inflammatory cell number; SABC detection display its obviously can reduce melanin positive cell number and optical density in epithelial layer.Show that the present invention has freckle removing and whitening effect.

Clinical data:

Thinner, the more dry people of skin can be obvious, may be failure to maintain, sun-proof work does imperfect, and the top layer making melanin easily float to skin caused, and is the modal cosmetic problem of female middle-aged (male also can produce black speck but rarely found).Usually at two cheeks, forehead, upper lip and chin, the reddish brown brown speckle of whole piece is produced, because the relation of color is commonly called as chloasma hepaticum again.The factor of Producing reason and deterioration comprises: pregnancy, oral contraceptive, some drugs (as antuepileptic) and Exposure to Sunlight.Most people is just difficult to nature once generation and disappears and take off.Opsonizing method, comprises Tretinoin A, azelaic acid, hydroquinone, fruit acid, L-ascorbic acid, kojic acid etc., coordinates sun-proof measure thoroughly, can obtain goodish therapeutic effect.

For reaching comparatively ideal therapeutic effect, take multiple method from Chinese medicine aspect, the present invention's facial film reaches treating both the principal and secondary aspects of a disease.Now be described below.

1 data and method

1.1 physical data

This group case is totally 50 examples, is women, 22 ~ 38 years old 28 age example; 38 ~ 45 years old 12 examples; More than 46 years old 10 examples.The course of disease is the shortest 6 months, reaches 10 years most.

1.2 clinical symptoms

Butterfly spot, chloasma show as differ in size, come in every shape, patch that the depth is indefinite, have and be dispersed in, merge in flakes or strip.Mainly be distributed in buccal both sides or mouth week or forehead.Skin lesion boundary is clear, and not swelling, nothing come off, and smooth surface, is not in the way.

1.3 method

1.3.1 external facial film: Flos Rosae Rugosae 15g, Radix Angelicae Sinensis 12g, Radix Rhodiolae 12g, Rhizoma Chuanxiong 13g, Radix Astragali 12g, Flos Albiziae 12g, Bombyx Batryticatus 13g, Herba Leonuri 12g, Flos Pelargonii 12g, Radix Saposhnikoviae 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 13g, Rhizoma Atractylodis Macrocephalae 13g, Radix Paeoniae Alba 12g, Radix Ampelopsis 13g, Radix Angelicae Pubescentis 12g, Radix Angelicae Dahuricae 12g, Flos Carthami 13g, Flos Rosae Chinensis 13g, common perilla 12g, Fructus Atriplicis Sibiricae 13g, by embodiment 2 one-tenth face film agent.This side has the effect of benefiting QI for activating blood circulation, face-beautifying and spot-removing.

1.3.3 the main acupuncture point of acupoint massage is coordinated to be the sun, yang white, Zanzhu, Baihui, Yingxiang, Sibai, ShiShimonoseki, dicang, cheek car, cheekbone Liao etc.Massage manipulation adopts the maneuver of Chinese and western combination, and wherein Chinese style maneuver is based on acupoint massage, and Western-style maneuver is to pacify massage, lympha toxin expelling.

The method treatment in every 2 days 1 time 2 months was 1 course for the treatment of, and all the other carry out the moisturizing of skin of face, sun-proof, isolation every day time.

2 results

In 50 routine patients, recovery from illness, speckle disappears 28 examples entirely, accounts for 56%, effectively (skin lesion disappearances) 14 example, and account for 28, invalid (raw hide damages and slightly improves) 8 is routine, and account for 16%, total effective rate is 84%.

3 discuss

The traditional Chinese medical science is thought, butterfly spot, chloasma are more common in and are educated menstrual woman, this aged women due to cause, housework busy, breed loss, many depression of liver-QI, stagnation of liver-QI is blood stasis then in addition.Golden Mirror of Medicine is said, and " be worried depressed, blood is weak not magnificent, and fiery dryness accumulated in the stomach and intestine is stagnant and be born on face, and women has it more." therefore I am based on SIWU TANG, enrich blood and invigorate blood circulation, help the medicine with dispersing the stagnated live-QI to relieve the stagnation of QI.Women's major part pressure of this age level is excessive, the impetuous irritability of disposition, and ZHU Dan-xi is said: through water person, also, the moon must from sun, therefore its color is red for cloudy blood .... through joining for gas, go because of gas, in bulk person is solidifying, will go and pain person's gas stagnant, the person of having a pain after row, also, also, reversed menstruation person gas is disorderly for the light also void of color for all void of QI and blood, purple person's gas stagnant, black then heat very also.The store blood of liver, main catharsis.Irritability is not dredged, disorder of movement of QI, qi depression to blood stasis, and kidney is the congenital foundation, and what punching was appointed is originally kidney, and collaterals of the uterus lies in kidney, and directly impact punching of suffering from a deficiency of the kidney is appointed, disharmony of Chong and Conception Channels, and qi depression to blood stasis is not smooth through water running.And the vital organs of the human body, the gas of extraordinary Fu-organ all can be gone up all in face, outside being revealed in, gradually in piebaldism.Radix Angelicae Sinensis with hemopoietic, the Radix Rehmanniae to grow blood, Radix Paeoniae yin fluid astringing, the logical gas up and down and in promoting the circulation of blood of Rhizoma Chuanxiong.Assistant is with Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, and Ramulus Cinnamomi can harmonizing yingfen and weifen, warm promoting blood circulation." " Yizong Jinjian surgery heart method " cloud: " and as in dirt dark, former in troubled thoughts depressed become ", stagnation of liver-QI blood stasis, strongly fragrant and fire-transformation, helps with Herba Leonuri clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, Fructus Gardeniae pathogenic fire purging relieving restlessness.

Claims

1. the face mask of traditional Chinese medicine of skin care speckle removing of invigorating blood circulation, it is characterized in that, described facial film comprises the crude drug of following parts by weight: 10 ~ 20 parts, Flos Rosae Rugosae, Radix Angelicae Sinensis 10 ~ 20 parts, Radix Rhodiolae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, Flos Albiziae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, Herba Leonuri 10 ~ 20 parts, Flos Pelargonii 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Ampelopsis 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Flos Rosae Chinensis 10 ~ 20 parts, common perilla 10 ~ 20 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts.

2. to invigorate blood circulation according to claim 1 the face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, described facial film comprises the crude drug of following parts by weight: 10 ~ 15 parts, Flos Rosae Rugosae, Radix Angelicae Sinensis 10 ~ 15 parts, Radix Rhodiolae 10 ~ 15 parts, Rhizoma Chuanxiong 10 ~ 15 parts, the Radix Astragali 10 ~ 15 parts, Flos Albiziae 10 ~ 15 parts, Bombyx Batryticatus 10 ~ 15 parts, Herba Leonuri 10 ~ 15 parts, Flos Pelargonii 10 ~ 15 parts, Radix Saposhnikoviae 10 ~ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 15 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Ampelopsis 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Flos Rosae Chinensis 10 ~ 20 parts, common perilla 10 ~ 20 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts.

3. to invigorate blood circulation according to claim 1 the face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, described facial film comprises the crude drug of following parts by weight: 10 ~ 20 parts, Flos Rosae Rugosae, Radix Angelicae Sinensis 10 ~ 20 parts, Radix Rhodiolae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, the Radix Astragali 10 ~ 20 parts, Flos Albiziae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, Herba Leonuri 10 ~ 20 parts, Flos Pelargonii 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 15 parts, Radix Ampelopsis 10 ~ 15 parts, Radix Angelicae Pubescentis 10 ~ 15 parts, the Radix Angelicae Dahuricae 10 ~ 15 parts, 10 ~ 15 parts, Flos Carthami, Flos Rosae Chinensis 10 ~ 15 parts, common perilla 10 ~ 15 parts, Fructus Atriplicis Sibiricae 10 ~ 15 parts.

4. invigorate blood circulation according to any one of claims 1 to 3 the preparation method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, the preparation method of described facial film comprises:

B, the roseleaf alcohol extraction will gathered again are component 2;

5. to invigorate blood circulation according to claim 4 the preparation method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, in described step a, first Radix Rhodiolae, Radix Saposhnikoviae, common perilla and Pseudobulbus Bletillae (Rhizoma Bletillae) steam method are distilled according to described number, obtain crystal, cross 100-120 order dusting cover, for subsequent use as component 1.

6. to invigorate blood circulation according to claim 4 the preparation method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, in described step b, comprise the step of extraction, the chopping of the roseleaf of collection has been placed in lid stainless steel cask, has added 70% ethanol, quality is 0.8-1 times of coarse powder, stir, moistening airtight placement more than 1 hour, makes abundant expansion; Drug sample after moistening expansion is mixed pine by filter plate gauze bag parcel again bottom percolator after paving does loose, then powder is contained with rustless steel spoon, uniform loading percolator, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitable pressurization, medicated powder must not load 2/3 eminence exceeding percolator; Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, then slowly add 70% ethanol; Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, control percolation speed and be generally 1000g medical material outflow 2 ~ 3ml per minute, filtrate puts into liquid container, and pours ethanol time emptying into liquid container; Merged by percolate and leave standstill, heating is concentrated into paste, stand for standby use, becomes component 2.

7. to invigorate blood circulation according to claim 4 the preparation method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, in described step c, all the other raw materials add the soak with ethanol 4-6 hour accounting for its quality 5-10 times amount, heating extraction 2 times, each 1-2 hour, merge extractive liquid, supernatant is removed after leaving standstill, then 100-120 order filters, be the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.25 filtrate, leave standstill and put into economic benefits and social benefits vacuum concentrator and mix, when first filtrate being concentrated into 80 DEG C, relative density is the concentrated solution of 1.32, insert 0 ~ 5 DEG C of deepfreeze again 24 hours, cold preservation liquid is added the filter aid kieselguhr of 0.3%, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 0.1g extractum, as component 3.

8. to invigorate blood circulation according to claim 4 the preparation method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, in described steps d, three kinds of component mixing of above-mentioned steps being extracted, stir, heating, mediation substrate, substrate selects propolis, ultraviolet sterilization bottling cold preservation.

9. to invigorate blood circulation according to claim 8 the preparation method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, it is propolis or Mel that the present invention is in harmonious proportion substrate used.

10. to invigorate blood circulation according to any one of claim 1 ~ 9 using method of face mask of traditional Chinese medicine of skin care speckle removing, it is characterized in that, facial film of the present invention is not containing antiseptic, necessary cold preservation, each just before going to bed after clean, by facial film uniform application in face, and by middle finger finger belly at face message 15-20 minute, after fully absorbing to it, wash away.