CN104873446A - Cinnamon oil containing toothpaste - Google Patents
Cinnamon oil containing toothpaste Download PDFInfo
- Publication number
- CN104873446A CN104873446A CN201510277040.5A CN201510277040A CN104873446A CN 104873446 A CN104873446 A CN 104873446A CN 201510277040 A CN201510277040 A CN 201510277040A CN 104873446 A CN104873446 A CN 104873446A
- Authority
- CN
- China
- Prior art keywords
- toothpaste
- oleum cinnamomi
- parts
- chinese medicine
- propolis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- HUTYZQWCTWWXND-NCTFTGAASA-N taraxasterol Natural products C[C@H]1[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@H](O)[C@@]2(C)CCC1=C HUTYZQWCTWWXND-NCTFTGAASA-N 0.000 description 1
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Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of toothpaste, particularly to cinnamon oil containing toothpaste which is prepared from the following raw materials in percentage by weight: 0.2-1.5% of cinnamon oil, 20-30% of light calcium carbonate, 20-30% of silica, 0.1-0.7% of mint oil, 20-30% of a humectant, 1.5-2.5% of a foaming agent, 1.2-2.7% of a thickener, 0.03-0.15% of xylitol, 0.01% of saccharin, 0.02-0.05% of propolis, 0.05-0.15% of methyl 4-hydroxybenzoate and the balance of distilled water. Traditional Chinese medicine components are further added in the cinnamon oil containing toothpaste; the cinnamon oil containing toothpaste prepared through a preparation method disclosed by the invention has the efficacities of clearing away heat and toxic materials, antisepsis and anti-inflammation, can clear heat and downbear fire, restrain oral cavity malignant bacteria and protect teeth, and can effectively prevent and treat oral diseases including dental ulcer, tooth gall, alveolar abscess, gingivitis, periodontitis and pulpitis.
Description
Technical field
The present invention relates to technical field of toothpaste, be specifically related to a kind of toothpaste containing Oleum Cinnamomi.
Background technology
Toothpaste commonly uses in people's daily life, and improved being formed by dentifrice, early stage dentifrice mainly uses calcium carbonate to be surfactant as abrasivus, with soap.Along with developing rapidly of science and technology, toothpaste industry also obtains very large improvement, is the development and application of new abrasivus, wetting agent, thickening agent and surfactant on the one hand, tooth paste product quality is constantly upgraded; On the other hand, toothpaste also from the common function development that cleans the teeth be add medicine become the dental care product preventing and treating odontopathy, the most outstanding is add fluorine toothpaste, and dental caries sickness rate is greatly reduced.
The tooth that a bite is firm, pure and fresh implication, everybody wants to have.But enter the manhood, the sickness rate of periodontal rises gradually, and with advancing age, its order of severity is also constantly deepened.Protection gingiva, periodontal tissue, seem more urgent for adult.Part Chinese herbal toothpaste really can play the effect of general protection tooth, tooth age, periodontal tissue.Such as, mica filled polypropylene, it is hemorrhage for age that it can prevent rapidly tooth, the oral problem such as prevention tooth inflammation in age, periodontitis, tooth atrophy in age.Certainly, this depends on the active component of YUNNAN BAIYAO in toothpaste, effectively can improve tooth age, periodontal tissue and the oral cavity blood circulation with regard to film, improve the supply of periodontal tissue and oral cavity mucous membrane tissue nutrient, strengthen tooth age, periodontal, tooth and the oral cavity resistance against diseases with regard to film.
The patent retrieved about toothpaste is as follows:
1, Chinese patent, title: Chinese medicinal toothpaste application number 03159651.7 applies for (patent right) people: Liuzhou Radiz Zanthoxyli Co., Ltd. makes a summary: the present invention relates to Chinese medicinal toothpaste technical field, the content of its Chinese herbal medicine composite in its lotion of toothpaste is 0.05-1.5%, at least includes the murraya paniculata concrete of 10% in this Chinese herbal medicine composite; This murraya paniculata concrete is by the granule materials of Folium Et Cacumen Murrayae pulverizing medicinal materials to 0.1-l0 mm in size; Ethanol using 40-90% is as solvent, and be l-l00 milliliter seepage pressure effects per minute with percolation speed, percolate is through decompression recycling ethanol, being concentrated into relative density is after the clear paste of 1.0-1.3, regulate acid-base value, make pH value be 7-l0, and control the obtained thing that yield is 50-150%.This toothpaste in use has stronger subduing swelling and detoxicating, promoting the circulation of QI to relieve pain, eliminating stagnation removing blood stasis dredging collateral dispel the wind, the effect of diuretic parasite killing,, tooth hemorrhage to toothache, tooth age age scorching, periodontal abscess, the oral cavities such as pericoronitis, oral ulcer, pharyngolaryngitis and dental disorders have more significant prophylactic-therapeutic effect, and can use chronically safely.
2, Chinese patent, title: a kind of toothpaste containing Chinese medicine extract and preparation method thereof and application; Application number 03128352.7 applies for (patent right) people: make a summary in Beijing Jiangzhong High-Tech Investment Limited Liability Company: the present invention relates to a kind of toothpaste containing Chinese medicine extract, especially containing the toothpaste of Radix Curcumae class Chinese medicine extract, and preparation method thereof control the application of tooth with whitening.The addition that can be used as the Chinese medicine extract that Radix Curcumae class is used as medicine is 0.1-10% of toothpaste gross weight.This Chinese medicine extract is specially adapted to except smoking patch, tea speckle, and the tooth paste product be made up of it, appearance luster is light, constant product quality, and the whitening effect that cleans the teeth is obvious.
3, Chinese patent, title: for the toothpaste and preparation method thereof of auxiliary treatment gingivitis; Application number 2013l0ll3804.8 applies for that (patent right) people: Liu Bingtian makes a summary: the invention provides a kind of toothpaste for auxiliary treatment gingivitis, described toothpaste comprises the traditional Chinese medicine composition extract liquid of the auxiliary treatment gingivitis of 20%-30%, 2%-4% binding agent, 18%-28% abrasivus, 40%-50% wetting agent, 1%-3% surfactant, 1%-2% sweeting agent, the water of 0.5%-1.5% stabilizing agent, 1.5%-2.5% antibacterial and surplus.Toothpaste provided by the invention can effectively improve gingival index and plaque index, alleviates gingivitis degree, has well help effect to treatment gingivitis.
Periodontitis, toothache, the oral diseases such as hemodia annoying the life of people always; Current Chinese herbal toothpaste kind is a lot, and its active ingredient, mostly from natural animal-plant, is compared other chemical synthetic drug, had zest little, and the feature that toxic and side effects is little is accepted extensively by people; It mainly adds corresponding Chinese medicine ingredients to form Chinese medicinal toothpaste in the toothpaste blind body substrate of composition toothpaste, although these compositions have certain suppression oral cavity noxious bacteria, and control periodontitis, the effect of anti-inflammatory analgesic; But possess multi-efficiency at present, the toothpaste of comprehensive solution oral disease is actually rare.
Summary of the invention
The object of the present invention is to provide a kind of toothpaste containing Oleum Cinnamomi; Oleum Cinnamomi is added in toothpaste; play the effect killing harmful levels of pathogens in skin and oral cavity; the effect that the toothpaste that the present invention prepares has resolving heat and reducing pathogenic fire, suppresses oral cavity noxious bacteria, fresh breath, takes care of one's teeth, can also treat the oral diseases such as oral ulcer, gingival swelling and pain, alveolar abscess, tooth inflammation in age, periodontitis, pulpitis by effectively preventing.
In order to realize object of the present invention, the present invention adopts following technical scheme:
Containing a toothpaste for Oleum Cinnamomi, it is characterized in that, comprise the raw material of following weight percentage:
Oleum Cinnamomi 0.2% ~ 1.5%; Precipitated calcium carbonate 20% ~ 30%; Silicon dioxide 20% ~ 30%; Oleum menthae 0.1% ~ 0.7%; Wetting agent 20% ~ 30%; Foaming agent 1.5% ~ 2.5%; Thickening agent 1.2% ~ 2.7%; Xylitol 0.03% ~ 0.15%; Glucide 0.01%; Propolis 0.02% ~ 0.05%; Methyl parahydroxybenzoate 0.05% ~ 0.15%; Distilled water surplus.
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, also add Chinese medicine ingredients further in toothpaste, its weight ratio mark is 5% ~ 10%.
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, described Chinese medicine ingredients comprises the component of following parts by weight: Calyx Seu Fructus Physalis 10 ~ 17 parts, Indigo Naturalis 10 ~ 15 parts, Herba Asari 12 ~ 18 parts, Herba Taraxaci 6 ~ 10 parts, Rhizoma Begoniae Fimbristipulatae 2 ~ 5 parts, Radix Platycodonis 3 ~ 5 parts, Cortex Moutan 5 ~ 8 parts.
Above-mentioned propolis is ground into 100 ~ 120 object propolis powder.
Above-mentioned wetting agent is one or more in glycerol, propylene glycol and sorbitol; Described foaming agent is dioctyl sodium sulphosuccinate or lauroyl sulfoacetic acid sodium; Described thickening agent is one or more in sodium alginate, xanthan gum, guar gum, carrageenin, Cornu Cervi pectin and carrageenan.
The preparation method step of the above-mentioned toothpaste containing Oleum Cinnamomi is as follows:
(1) respectively each component in Chinese medicine ingredients is ground into 50 ~ 80 orders with pulverizer, then the abundant mix homogeneously of each component pulverized is got by weight, obtain mixture, in mixture, add determining alcohol is 80% ~ 90% ethanol, the addition of ethanol is 2 ~ 3 times of volume of mixture, reflux 4 ~ 7 hours at 60 ~ 85 DEG C, filter, obtain backflow;
(2) backflow is carried out distilling under reduced pressure, remove ethanol, obtain solid fraction object, solid fraction object is carried out drying then powder
Be broken into powder, obtain the Chinese medicine ingredients for the preparation of the toothpaste containing Oleum Cinnamomi;
(3) by the Chinese medicine ingredients that obtains according to proportioning and silicon dioxide; Precipitated calcium carbonate; Oleum Cinnamomi; Oleum menthae; Wetting agent; Foaming agent; Thickening agent; Xylitol; Glucide; Propolis; Methyl parahydroxybenzoate fully mixes, and then adds distilled water, even with blender strong stirring, makes the mastic of certain viscosity;
(4) the mastic grinder obtained is carried out twice grinding, first time grinding 1 ~ 2 hour, and then carry out second time grinding, second time grinding 1 hour, carry out vacuum outgas after second time grinding, until vacuum reaches-0.097Mpa, the vacuum outgas time is about 40 ~ 45 minutes; Mastic degassed rear standing a period of time, obtain product.
The volatile oil that above-mentioned Oleum Cinnamomi is the dry branch of canella Cortex Cinnamomi Cinnamomum cassia Presl, leaf obtains through steam distillation.Oleum Cinnamomi is widely used in medicine, food and light industry industry.All be classified as top grade in history tree, think have mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, the effects such as promoting blood circulation to restore menstrual flow.The traditional Chinese medical science is as controlling sexual impotence, and cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathe heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, and emmenagogue uses.Modern study shows, and Cortex Cinnamomi has the multiple effect such as antibacterial, antitumor, antiulcer, antipyretic, analgesia spasmolytic, tonifying YANG, parasite killing.Oleum Cinnamomi has natural insect-repelling parasite killing, fungicidal effect, again can not contaminated food.Oleum Cinnamomi is to common bacteria (escherichia coli, Salmonella, bacillus subtilis, Bacillus thuringiensis etc.), yeast (beer yeast, bakery yeast etc.), mycete (aspergillus niger, aspergillus oryzae, Aspergillus flavus, penicillium sp, Trichoderma spp., Mucor, rhizopus etc.) all have very strong inhibitory action, Oleum Cinnamomi is added in toothpaste, there is the effect killing harmful levels of pathogens in skin and oral cavity.
In above-mentioned Chinese medicine ingredients, described Calyx Seu Fructus Physalis Classification system is:
physalis alkekengi L.var.franchetiianother name: Calyx seu Fructus physalis, Radix Ribis manschurici, red lantern, Miss, golden Miss, golden lamp, aunt grind, cluck bird; Calyx Seu Fructus Physalis is Solanaceae Physalis perennial root herbaceous plant, medicinal fruit, have heat-clearing and toxic substances removing, sore-throat relieving, reduce phlegm, diuresis, soothing the liver and antitussive diuresis function.Cure mainly depression of liver-QI, nephritis, hepatitis; Vitamin C deficiency, phlegm-heat cough.Calyx Seu Fructus Physalis plant as Chinese medicine, containing Calyx seu fructus physalis alcohol (
physanol) A, B; In seed containing this sterol of standing grain (
gramisterol), obtusifoliol (
obtusifoliol), cycloartanol (
cycloartanol), cycloartenol (
cycloartenol) etc. chemical composition.Cold in nature, bitter in the mouth, cures mainly lung-heat laryngalgia, pneumonopathy, parotitis, hot hernia, stranguria with blood; External treatment skin sore swells, pemphigus, gingival swelling and pain.There is heat-clearing and toxic substances removing, sore-throat relieving, reduce phlegm, effect of diuresis.Seedling, leaf, stem, root all can be used as medicine, bitter in the mouth, cold, nontoxic.Seedling, leaf, stem are containing physagulin A0.02%, B0.002%, C (deoxidation physagulin A).Sour in the mouth, hardship, cold in nature, there are heat-clearing and toxic substances removing, diuresis function.Cough, jaundice, malaria, edema, furuncle, erysipelas etc. can be controlled.Root bitter in the mouth, cold in nature, there are heat clearing away, diuretic function.Can treating malaria disease, jaundice, hernia.Seed is sour, flat, nontoxic.The persistent calyx expanded can be used as medicine, have refrigerant, reduce phlegm, antitussive, diuresis effect.Fruity is sour-sweet, slightly bitterness, and peel taste is extremely bitter, and both all can be used as medicine, and bright and beautiful lamp fruit claims " I " on Chinese medicine, can heat-clearing and toxic substances removing, clearing phlegm and relieving cough, treatment chronic tracheitis.
Described Indigo Naturalis: be acanthaceous vegetable acanthaceous indigo
baphicacanthus cusia (Nees) Bremek.polygonaceae plant polygonum tinctorium ait.
polygonum tinctorium Aitor cruciferae isatis
isatis indigotica Fort.Leaf or stem and leaf through processing obtained dried powder, agglomerate or granule.Another name: indigo flower, Concha Meretricis Seu Cyclinae powder, blue or green cylinder flower, Lan Lu, shallow lake flower, indigo foam flower; The effects such as nature and flavor are salty-cold, have heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, pathogenic fire purging arresting convulsion.It is mainly used in epidemic febrile disease intenseness of heat, macule, and spit blood, spit blood, pharyngalgia aphtha, pediatric epilepsy scared, skin ulcer swells, erysipelas, snake bite and insect sting etc." Kaibao Bencao ": " heating of fainting from fear, pestilent headache cold and heat, decoct water and grind and take it for all poison of drug of principal solution, infantile pyretic diseases.Also rub deposited herpes simplex, dislike the poison such as swollen, incised wound, hematochezia, Serpentis dog.4 " book on Chinese herbal medicine covers bamboo fish trap ": " drive epidemic disease headache, hold back the red speckle of typhoid fever, water is taken after mixing with liquid it for eliminating pathogen in the liver, only spouting diarrhea, expectorant water on the diaphragm that disappears.”
Compendium of Material Medica: " reduce phlegm and internal heat tired, spit blood, spitting of blood, speckle skin ulcer, the erosion of vulva, kill and dislike worm." " book on Chinese herbal medicine is stated ": " control apoplexy, wind syndrome of head, hypochondriac pain, clonic convulsion, tremor, dizzy, cough, chronic cough, vomiting, tongue bleeding, cough blood, colic of cold type." Indigo Naturalis all has stronger inhibitory action to microsporum canis, disconnected tineatonsurans, microsporon gypseum, purple tinea bacterium, trichophyton gypseum, red mentagrophytes, acrothesium floccosum etc., can treat gingivitis.
Described Herba Asari, another name: magnificent Herba Asari, basin grass Herba Asari, Latin literary fame:
asarum sieboldii Miq.aristolochiaceae, asarum perennial herb; Herba Asari is as medicinal plants, and Shi Zai Qin Han Shennong's Herbal, Shennong's Herbal is classified as top grade.Herba Asari root is thin, color sallow, leaf color are green, the peppery numb tongue of acrid in the mouth.Warm in nature, slightly poisonous.GUIXIN, lung, kidney channel.Dispel the wind, cold expelling, warming the lung, Hang Shui, have one's ideas straightened out, the effect of antipyretic-antalgic, has the curative effects such as antibacterial, antiinflammatory, hemostasis, analgesia.Control headche due to wind-cold, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.In addition, Herba Asari also has anti inflammatory immunity, local anesthesia, raising metabolism, antibacterial action, also can be used for the leukopenia of Chemotherapy of Tumor Patients and caused by radiation.Calm, analgesic activity Herba Asari volatile oil has obvious central inhibitory action, and low dose can make animal peace and quiet, taming, autonomic activities minimizing; Heavy dose can make animal sleep, and has obvious anticonvulsant action.Herba Asari decoct gavages also has analgesic activity.Its stronger analgesic activity is the valuable pharmacological basis of its treatment head general pain, toothache etc.. antiinflammatory, immunosuppressant and antiallergic action Herba Asari volatile oil gavage or inject all obvious antiinflammatory action.. antibacterial, antivirus action kakuol preserved material, volatilization wet goods have certain In-vitro Inhibitory Effect to gram positive bacteria, bacillus subtilis and Bacillus typhi, and decoct also has inhibitory action to tubercule bacillus and Bacillus typhi.Herba Asari volatile oil is to multiple fungus as Aspergillus flavus, Aspergillus niger, Candida albicans etc. all have inhibitory action, and antibacterial effective ingredient is safrole.α-asaricin has the effect suppressing respiratory syncytial virus propagation.
Described Herba Taraxaci (Classification system:
taraxacum mongolicum Hand.-Mazz.) Compositae,
Dandelion herbaceos perennial.Herba Taraxaci another name Herba crotalariae albidae, Po Poding, Hua Hualang etc.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant.Containing taraxol, taraxerol, ψ-Portugal's Herba Taraxaci sterol, taraxasterol, β-Amyrin, stigmasterol, cupreol, choline, organic acid, fructose, sucrose, glucose, glycoside and resin, rubber etc. in root.Leaf is containing phylloxanthin, violaxanthin, phylloquinone, vitamin C (50 ~ 70 milligrams/100 grams) and vitamin D (5 ~ 9 milligrams/100 grams).Nature and flavor are sweet, micro-hardship, cold.Return liver, stomach warp.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.Herba Taraxaci is raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.
Described Rhizoma Begoniae Fimbristipulatae (formal name used at school:
begonia fimbristipula) have another name called Radix Semiaquilegiae, red autumnal leaves, loose blood, dragon and tiger leaf, night crosses red, red water certain herbaceous plants with big flowers, is a kind of Chinese crude drug.For bulb or the Herb of Begoniaceae plant Radix Semiaquilegiae.Function cures mainly clearing away heat and cooling blood, promoting blood circulation and detoxication.Control summer-heat hyperpyrexia, cough due to lung-heat, spitting of blood, osteopatia sprain, blood stasis pain, sore scabies, burn due to hot liquid or fire.Property sweet-puckery flavor is cool, nontoxic.Guangzhou army " conventional Chinese herbal medicine handbook ": " heat-clearing and toxic substances removing, moistens dryness and relieve cough, dissipating blood stasis for subsidence of swelling.Control exogenous high fever.Heatstroke is had a fever, cough due to lung-heat, treating swelling and pain by traumatic injury.Fresh goods is mashed, and can apply malignant boil furunculosis." " conventional Chinese herbal medicine color atlas ": " controls pneumonia cough, spitting of blood, chronic bronchitis." " the practical Chinese herbal medicine in Guangxi newly selects ": " removing heat from blood and promoting blood circulation, anti-inflammatory analgetic.Cure mainly spitting of blood, abdominal pain due to blood stasis, bruise, fracture, burn, tinea scabies ".
Described Radix Platycodonis, Classification system:
platycodon grandiflorus (Jacq.) A. DC. another name burden flower, Radix Platycodonis, mitral flower, be herbaceos perennial, function cures mainly: lung qi dispersing, and sore-throat relieving eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.Pharmacological action: 1. eliminate the phlegm and antitussive effect, cause stimulation to a certain degree to pharyngolaryngeal mucosa and gastric mucosa when Saponin is oral contained by Radix Platycodonis, cause respiratory mucosa hypersecretion reflectingly, sputum is diluted, impel it to discharge, rough kikyosaponin has antitussive effect; 2. hypoglycemic activity; 3. antiinflammatory action: thick kikyosaponin has antiinflammatory action, and Radix Platycodonis is without direct antibacterial action, but its water extract can strengthen macrophage phagocytic function, strengthens the sterilizing power of neutrophilic leukocyte.Improve the activity of lysozyme.4. suppress gastric secretion and antiulcer action; 5. other effect: thick kikyosaponin has calmness, analgesia and refrigeration function.
Described Cortex Moutan, has another name called Cortex Moutan, Chinese medicine name.For ranunculaceae peony (Classification system: Paeonia
Suffruticosa Andr.) dry root bark.Compendium of Material Medica: " nourishing YIN to lower pathogenic fire separates speckle poison, throat, diuresis stasis.Descendant specially controls fire mutually with yellow tiller, does not know that the merit of Cortex Moutan more wins also.Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it." modern study, contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action; The methanolic extract of Cortex Moutan has suppression Platelet; Paeonol has the effects such as central inhibitory action and atherosclerosis, diuresis, antiulcer such as calmness, cooling, antipyretic, analgesia, spasmolytic.Cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.The caused various inflammatory reactions such as Cortex Moutan water decoction on Carrageenan edema, adjuvant-induced arthritis and Arthus reaction are inhibited, and Cortex Moutan can increase coronary flow to the anesthetized dog heart, reduces cardiac output, reduces the effect of left room work done.Cortex Moutan decoct all has stronger antibacterial action to bacillus subtilis, escherichia coli, Bacillus typhi, Salmonella paratyphi, Bacillus proteus, bacillus pyocyaneus, staphylococcus, Hemolytic streptococcus, streptococcus pneumoniae, vibrio cholera etc., leaf of paeonia suffruticosa ardr. decoct has remarkable antibacterial action to dysentery bacterium, bacillus pyocyaneus and staphylococcus aureus, and its active ingredient is gallic acid.
Described propolis is the resin that Apis gathers from plant spore or trunk, is mixed into palatine gland on it, wax
A kind of colloidal solid thing with aromatic odor that the secretions of gland processes.Classification system is: Colla Apis, is the yellowish-brown of repairing secreted by Nidus Vespae or the stickums of pitchy such as Apidae animal apis cerana, can be used as medicine.It is cold in nature, bitter in the mouth, pungent, has skin moistening granulation promoting, effect of anti-inflammatory analgetic, can treat gastric ulcer, oral ulcer, burn and scald, skin splitting pain, the diseases such as radioprotective; Propolis ethanol soluble extraction 100 mcg/ml concentration has inhibitory action to 20 kinds in 25 kinds in 39 kinds of antibacterials and 39 kind of plant funguses, its be to gram-positive bacterium and acid fast bacteria the most responsive.The propolis alcohol of 1%-10% or ether extract have inhibitory action to the fungus, tinea bacterium, floccus mentagrophyte, red mentagrophytes, Microsporum ferrugineum, microsporon gypseum, microsporum canis, brain shape tinea bacterium, trichophyton gypseum, trichophyton tonsurans, purple tinea bacterium etc. that the mankind are common.Good killing action is had to cucumber mosaic virus, tobacco mottle virus, tobacco necrosis virus and influenza A.The breeding of herpesvirus can be suppressed and significantly alleviate the infection of vaccinia virus; As far back as the fifties, the oral diseases such as recurrent aphtha, oral erosion, ulcer successfully treated by external just application propolis ointment.Abundant contained by propolis and the bioactive substance of uniqueness, make it have the several functions such as antibacterial, antiinflammatory, antipruritic, antioxidation, enhancing immunity, blood sugar lowering, blood fat reducing, antitumor, have medical, health-care effect widely to human body.
compared with prior art, the invention has the beneficial effects as follows:
1, Oleum Cinnamomi adds in toothpaste by the present invention, and Oleum Cinnamomi has natural insect-repelling parasite killing, fungicidal effect, again can not contaminated food; Oleum Cinnamomi is to common bacteria (escherichia coli, Salmonella, bacillus subtilis, Bacillus thuringiensis etc.), yeast (beer yeast, bakery yeast etc.), mycete (aspergillus niger, aspergillus oryzae, Aspergillus flavus, penicillium sp, Trichoderma spp., Mucor, rhizopus etc.) all have very strong inhibitory action, Oleum Cinnamomi is added in toothpaste, there is the effect killing harmful levels of pathogens in skin and oral cavity.Also Chinese medicine ingredients is added further in toothpaste, and add Oleum menthae, the Oleum menthae added can not only play the taste of Chinese medicine of the Chinese medicine ingredients that antibacterial action can also effectively comprehensively add, taste of Chinese medicine is subtracted light, improve the abnormal smells from the patient of toothpaste, make toothpaste have a kind of light Herba Menthae delicate fragrance, use the effect playing fresh breath during toothpaste; Adding propolis can make the antibacterial action of toothpaste be enhanced, and propolis has good therapeutical effect to oral disease.
2, the Chinese medicine ingredients that the present invention adopts combines Calyx Seu Fructus Physalis; Indigo Naturalis; Herba Asari; Herba Taraxaci, Rhizoma Begoniae Fimbristipulatae, the active ingredient of Radix Platycodonis and this several Chinese medicinal material of Cortex Moutan; heat-clearing and toxic substances removing; anti-inflammation, the effect can play resolving heat and reducing pathogenic fire, suppressing oral cavity noxious bacteria, take care of one's teeth, can also treat the oral diseases such as oral ulcer, gingival swelling and pain, alveolar abscess, tooth inflammation in age, periodontitis, pulpitis by effectively preventing.
3, the toothpaste that the present invention obtains has stronger subduing swelling and detoxicating, anti-inflammation, the effect of anti-inflammatory and antalgic, the formation of halitosis and speckle can better be controlled, effective mitigation can be played to gingival hemorrhage, inflamed, pain, oral ulcer symptom, to dental disorders, there is more significant prophylactic-therapeutic effect, and Chinese medicine is lightly seasoned, can use chronically safely.
Detailed description of the invention
embodiment 1
Containing a toothpaste for Oleum Cinnamomi, it is characterized in that, comprise the raw material of following weight percentage:
Oleum Cinnamomi 0.2%; Precipitated calcium carbonate 20%; Silicon dioxide 20%; Oleum menthae 0.1%; Wetting agent glycerol 20%; Foaming agent dioctyl sodium sulphosuccinate 1.5%; Thickening agent sodium alginate 1.2%; Xylitol 0.03%; Glucide 0.01%; Propolis 0.02%; Methyl parahydroxybenzoate 0.05%; Distilled water surplus;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, also add Chinese medicine ingredients further in toothpaste, its weight ratio mark is 5%;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, described Chinese medicine ingredients comprises the component of following parts by weight: Calyx Seu Fructus Physalis 10 parts, Indigo Naturalis 10 parts, Herba Asari 12 parts, Herba Taraxaci 6 parts, Rhizoma Begoniae Fimbristipulatae 2 parts, Radix Platycodonis 3 parts, Cortex Moutan 5 parts;
Above-mentioned propolis is ground into 100 ~ 120 object propolis powder;
The preparation method step of the above-mentioned toothpaste containing Oleum Cinnamomi is as follows:
(1) respectively each component in Chinese medicine ingredients is ground into 50 ~ 80 orders with pulverizer, then the abundant mix homogeneously of each component pulverized is got by weight, obtain mixture, in mixture, add determining alcohol is 80% ~ 90% ethanol, the addition of ethanol is 2 ~ 3 times of volume of mixture, reflux 7 hours at 60 DEG C, filter, obtain backflow;
(2) backflow is carried out distilling under reduced pressure, remove ethanol, obtain solid fraction object, solid fraction object is carried out drying then powder
Be broken into powder, obtain the Chinese medicine ingredients for the preparation of the toothpaste containing Oleum Cinnamomi;
(3) by the Chinese medicine ingredients that obtains according to proportioning and silicon dioxide; Precipitated calcium carbonate; Oleum Cinnamomi; Oleum menthae; Wetting agent glycerol; Foaming agent dioctyl sodium sulphosuccinate; Thickening agent sodium alginate; Xylitol; Glucide; Propolis; Methyl parahydroxybenzoate fully mixes, and then adds distilled water, even with blender strong stirring, makes the mastic of certain viscosity;
(4) the mastic grinder obtained is carried out twice grinding, by levigate for granule excessively thick, really up to the mark, make mastic fine and smooth,
Evenly, stablize, first time grinding 1 ~ 2 hour, and then carry out second time grinding, second time is ground 1 hour, and carry out vacuum outgas after second time grinding, until vacuum reaches-0.097Mpa, the vacuum outgas time is about 40 minutes; Mastic degassed rear standing a period of time, obtain product.
embodiment 2
Containing a toothpaste for Oleum Cinnamomi, it is characterized in that, comprise the raw material of following weight percentage:
Oleum Cinnamomi 0.7%; Precipitated calcium carbonate 23%; Silicon dioxide 24%; Oleum menthae 0.3%; Wetting agent 23%; Foaming agent 1.7%; Thickening agent 1.7%; Xylitol 0.07%; Glucide 0.01%; Propolis 0.03%; Methyl parahydroxybenzoate 0.08%; Distilled water surplus;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, also add Chinese medicine ingredients further in toothpaste, its weight ratio mark is 6%;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, described Chinese medicine ingredients comprises the component of following parts by weight: described Chinese medicine ingredients comprises the component of following parts by weight: Calyx Seu Fructus Physalis 13 parts, Indigo Naturalis 11 parts, Herba Asari 14 parts, Herba Taraxaci 7 parts, Rhizoma Begoniae Fimbristipulatae 3 parts, Radix Platycodonis 3.5 parts, Cortex Moutan 6 parts;
Above-mentioned propolis is ground into 100 ~ 120 object propolis powder;
Above-mentioned wetting agent is one or more in glycerol, propylene glycol and sorbitol; Described foaming agent is dioctyl sodium sulphosuccinate or lauroyl sulfoacetic acid sodium; Described thickening agent is one or more in sodium alginate, xanthan gum, guar gum, carrageenin, Cornu Cervi pectin and carrageenan;
The preparation method step of the above-mentioned toothpaste containing Oleum Cinnamomi is as follows:
(1) respectively each component in Chinese medicine ingredients is ground into 50 ~ 80 orders with pulverizer, then the abundant mix homogeneously of each component pulverized is got by weight, obtain mixture, in mixture, add determining alcohol is 80% ~ 90% ethanol, the addition of ethanol is 2 ~ 3 times of volume of mixture, reflux 6 hours at 70 DEG C, filter, obtain backflow;
(2) backflow is carried out distilling under reduced pressure, remove ethanol, obtain solid fraction object, solid fraction object is carried out drying and is then ground into powder, obtain the Chinese medicine ingredients for the preparation of the toothpaste containing Oleum Cinnamomi;
(3) by the Chinese medicine ingredients that obtains according to proportioning and silicon dioxide; Precipitated calcium carbonate; Oleum Cinnamomi; Oleum menthae; Wetting agent; Foaming agent; Thickening agent; Xylitol; Glucide; Propolis; Methyl parahydroxybenzoate fully mixes, and then adds distilled water, even with blender strong stirring, makes the mastic of certain viscosity;
(4) the mastic grinder obtained is carried out twice grinding, by levigate for granule excessively thick, really up to the mark, make
Mastic is fine and smooth, even, stable, first time grinding 1 ~ 2 hour, and then carries out second time grinding, grinding for the second time 1 hour, and carry out vacuum outgas after second time grinding, until vacuum reaches-0.097Mpa, the vacuum outgas time is about 42 minutes; Mastic degassed rear standing a period of time, obtain product.
embodiment 3
Containing a toothpaste for Oleum Cinnamomi, it is characterized in that, comprise the raw material of following weight percentage:
Oleum Cinnamomi 1.1%; ; Precipitated calcium carbonate 26%; Silicon dioxide 27%; Oleum menthae 0.5%; Wetting agent sorbitol 27%; Foaming agent lauroyl sulfoacetic acid sodium 2.1%; Thickening agent carrageenin 2.3%; Xylitol 0.11%; Glucide 0.01%; Propolis 0.04%; Methyl parahydroxybenzoate 0.12%; Distilled water surplus;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, also add Chinese medicine ingredients further in toothpaste, its weight ratio mark is 8%;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, described Chinese medicine ingredients comprises the component of following parts by weight: Calyx Seu Fructus Physalis 15 parts, Indigo Naturalis 13 parts, Herba Asari 16 parts, Herba Taraxaci 8 parts, Rhizoma Begoniae Fimbristipulatae 4 parts, Radix Platycodonis 4 parts, Cortex Moutan 7 parts;
Above-mentioned propolis is ground into 100 ~ 120 object propolis powder;
The preparation method step of the above-mentioned toothpaste containing Oleum Cinnamomi is as follows:
(1) respectively each component in Chinese medicine ingredients is ground into 50 ~ 80 orders with pulverizer, then the abundant mix homogeneously of each component pulverized is got by weight, obtain mixture, in mixture, add determining alcohol is 80% ~ 90% ethanol, the addition of ethanol is 2 ~ 3 times of volume of mixture, reflux 5 hours at 80 DEG C, filter, obtain backflow;
(2) backflow is carried out distilling under reduced pressure, remove ethanol, obtain solid fraction object, solid fraction object is carried out drying then powder
Be broken into powder, obtain the Chinese medicine ingredients for the preparation of the toothpaste containing Oleum Cinnamomi;
(3) by the Chinese medicine ingredients that obtains according to proportioning and silicon dioxide; Precipitated calcium carbonate; Oleum Cinnamomi; Oleum menthae; Wetting agent sorbitol; Foaming agent lauroyl sulfoacetic acid sodium; Thickening agent carrageenin; Xylitol; Glucide; Propolis; Methyl parahydroxybenzoate fully mixes, and then adds distilled water, even with blender strong stirring, makes the mastic of certain viscosity;
(4) the mastic grinder obtained is carried out twice grinding, by levigate for granule excessively thick, really up to the mark, make mastic fine and smooth,
Evenly, stablize, first time grinding 1 ~ 2 hour, and then carry out second time grinding, second time is ground 1 hour, and carry out vacuum outgas after second time grinding, until vacuum reaches-0.097Mpa, the vacuum outgas time is about 43 minutes; Mastic degassed rear standing a period of time, obtain product.
embodiment 4
containing a toothpaste for Oleum Cinnamomi, it is characterized in that, comprise the raw material of following weight percentage:
Oleum Cinnamomi 1.5%; Precipitated calcium carbonate 30%; Silicon dioxide 30%; Oleum menthae 0.7%; Wetting agent 30%; Foaming agent 2.5%; Thickening agent 2.7%; Xylitol 0.15%; Glucide 0.01%; Propolis 0.05%; Methyl parahydroxybenzoate 0.15%; Distilled water surplus;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, also add Chinese medicine ingredients further in toothpaste, its weight ratio mark is 10%;
The above-mentioned toothpaste containing Oleum Cinnamomi, it is characterized in that, described Chinese medicine ingredients comprises the component of following parts by weight: Calyx Seu Fructus Physalis 17 parts, Indigo Naturalis 15 parts, Herba Asari 18 parts, Herba Taraxaci 10 parts, Rhizoma Begoniae Fimbristipulatae 5 parts, Radix Platycodonis 5 parts, Cortex Moutan 8 parts;
Above-mentioned propolis is ground into 100 ~ 120 object propolis powder;
Described wetting agent is propylene glycol and sorbitol; Described foaming agent is dioctyl sodium sulphosuccinate or lauroyl sulfoacetic acid sodium; Described thickening agent is sodium alginate and xanthan gum;
The preparation method step of the described toothpaste containing Oleum Cinnamomi is as follows:
(1) respectively each component in Chinese medicine ingredients is ground into 50 ~ 80 orders with pulverizer, then the abundant mix homogeneously of each component pulverized is got by weight, obtain mixture, in mixture, add determining alcohol is 80% ~ 90% ethanol, the addition of ethanol is 2 ~ 3 times of volume of mixture, reflux 4 hours at 85 DEG C, filter, obtain backflow;
(2) backflow is carried out distilling under reduced pressure, remove ethanol, obtain solid fraction object, solid fraction object is carried out drying and is then ground into powder, obtain the Chinese medicine ingredients for the preparation of the toothpaste containing Oleum Cinnamomi;
(3) by the Chinese medicine ingredients that obtains according to proportioning and silicon dioxide; Precipitated calcium carbonate; Oleum Cinnamomi; Oleum menthae; Wetting agent; Foaming agent; Thickening agent; Xylitol; Glucide; Propolis; Methyl parahydroxybenzoate fully mixes, and then adds distilled water, even with blender strong stirring, makes the mastic of certain viscosity.
(4) the mastic grinder obtained is carried out twice grinding, by levigate for granule excessively thick, really up to the mark, make mastic fine and smooth, even, stable, first time grinding 1 ~ 2 hour, and then carry out second time grinding, second time grinding 1 hour, carry out vacuum outgas after second time grinding, until vacuum reaches-0.097Mpa, the vacuum outgas time is about 45 minutes; Mastic degassed rear standing a period of time, obtain product.
Effect:
For verifying the effect that the Chinese medicinal toothpaste that the present invention protects plays oral disease further, further illustrate good result of the present invention through overtesting below.Specific as follows:
Select the volunteer suffering from oral ulcer, gingival swelling and pain, alveolar abscess, tooth inflammation in age, periodontitis, pulpitis oral disease participated in voluntarily, Chinese medicinal toothpaste obtained by Example 1-4, test, test method is: every day sooner or later respectively once, consumption is the half of ordinary toothpaste, use after 5-7 days, observed result.Clinical statistics standard is as shown in table l, and curative effect clinical data statistics is as shown in table 2.
From above-mentioned clinical data, the present invention has good curative effect for oral diseases such as treatment oral ulcer, gingival swelling and pain, alveolar abscess, tooth inflammation in age, periodontitis, pulpitiss.
Claims (6)
1., containing a toothpaste for Oleum Cinnamomi, it is characterized in that, comprise the raw material of following weight percentage:
Oleum Cinnamomi 0.2% ~ 1.5%; Precipitated calcium carbonate 20% ~ 30%; Silicon dioxide 20% ~ 30%; Oleum menthae 0.1% ~ 0.7%; Wetting agent 20% ~ 30%; Foaming agent 1.5% ~ 2.5%; Thickening agent 1.2% ~ 2.7%; Xylitol 0.03% ~ 0.15%; Glucide 0.01%; Propolis 0.02% ~ 0.05%; Methyl parahydroxybenzoate 0.05% ~ 0.15%; Distilled water surplus.
2. the toothpaste containing Oleum Cinnamomi as claimed in claim 1, it is characterized in that, also add Chinese medicine ingredients further in toothpaste, its weight ratio mark is 5% ~ 10%.
3. the toothpaste containing Oleum Cinnamomi according to claim 2, it is characterized in that, described Chinese medicine ingredients comprises the component of following parts by weight: Calyx Seu Fructus Physalis 10 ~ 17 parts, Indigo Naturalis 10 ~ 15 parts, Herba Asari 12 ~ 18 parts, Herba Taraxaci 6 ~ 10 parts, Rhizoma Begoniae Fimbristipulatae 2 ~ 5 parts, Radix Platycodonis 3 ~ 5 parts, Cortex Moutan 5 ~ 8 parts.
4. the toothpaste containing Oleum Cinnamomi according to claim 1, it is characterized in that, described propolis is ground into 100 ~ 120 object propolis powder.
5. the toothpaste containing Oleum Cinnamomi according to claim 1, is characterized in that, described wetting agent is one or more in glycerol, propylene glycol and sorbitol; Described foaming agent is dioctyl sodium sulphosuccinate or lauroyl sulfoacetic acid sodium; Described thickening agent is one or more in sodium alginate, xanthan gum, guar gum, carrageenin, Cornu Cervi pectin and carrageenan.
6. the toothpaste containing Oleum Cinnamomi as claimed in claim 1, is characterized in that, the preparation method step of the described toothpaste containing Oleum Cinnamomi is as follows:
(1) respectively each component in Chinese medicine ingredients is ground into 50 ~ 80 orders with pulverizer, then the abundant mix homogeneously of each component pulverized is got by weight, obtain mixture, in mixture, add determining alcohol is 80% ~ 90% ethanol, the addition of ethanol is 2 ~ 3 times of volume of mixture, reflux 4 ~ 7 hours at 60 ~ 85 DEG C, filter, obtain backflow;
(2) backflow is carried out distilling under reduced pressure, remove ethanol, obtain solid fraction object, solid fraction object is carried out drying then powder
Be broken into powder, obtain the Chinese medicine ingredients for the preparation of the toothpaste containing Oleum Cinnamomi;
(3) by the Chinese medicine ingredients that obtains according to proportioning and silicon dioxide; Precipitated calcium carbonate; Oleum Cinnamomi; Oleum menthae; Wetting agent; Foaming agent; Thickening agent; Xylitol; Glucide; Propolis; Methyl parahydroxybenzoate fully mixes, and then adds distilled water, even with blender strong stirring, makes the mastic of certain viscosity;
(4) the mastic grinder obtained is carried out twice grinding, first time grinding 1 ~ 2 hour, and then carry out second time grinding, second time grinding 1 hour, carry out vacuum outgas after second time grinding, until vacuum reaches-0.097Mpa, the vacuum outgas time is about 40 ~ 45 minutes; Mastic degassed rear standing a period of time, obtain product.
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| TWI730287B (en) * | 2019-01-31 | 2021-06-11 | 楊曉婷 | Preparation method and usage of oral composition |
| TWI730286B (en) * | 2019-01-31 | 2021-06-11 | 楊曉婷 | Preparation method and usage of oral composition |
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| CN104873446B (en) | 2018-02-06 |
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Effective date of registration: 20210513 Address after: No. 86, Zhenhua North Road, Shenshan Industrial Park, Jianggao Town, Baiyun District, Guangzhou, Guangdong 510450 Patentee after: GUANGZHOU CHINA HAN ORAL PRODUCTS Co.,Ltd. Address before: 530300 No.80, Liuming Road, Hengzhou Town, Heng County, Nanning City, Guangxi Zhuang Autonomous Region Patentee before: Mo Mingxin |