KR20130069518A - A composition for treating skin diseases comprising complex extract and a cosmetic and skin externals using the same - Google Patents

Abstract

PURPOSE: A composition containing a complex extract is provided to alleviate and treat skin diseases, and to manufacture a cosmetic material or an external use skin formulation for alleviating skin diseases. CONSTITUTION: A composition for treating skin diseases contains 5-50wt% of a complex extract containing Torilidis Fructus, Phaseoli radiati semen, Glycyrrhizae radix, Cimicifugae rhizoma, Persicae semen, Lithospermi radix, Bletillae rhizoma, Dictamni radicis cortx, Aconiti koreani tuber, Angelicae dahuricae radix, Coptidis rhizoma, Angelicae tenuissimae radix, green tea, Nardostachyos rhizoma, Scutellariae radix, Lonicerae flos, Phellodendri cortex, Ampelopsis radix, Forsythiae fructus, Kalopanax pictus nakai, Ginkgonis folium, Mori folium, Portulacae herba, and Kochiae fructus. Skin diseases include atopic dermatitis, acne, melasma, skin erosion, skin trouble, eczema, athlete's foot, dermatitis, or itching. A cosmetic composition for alleviating skin diseases contains the complex extract as an active ingredient.

Description

Composition for treating skin diseases comprising complex extract and a cosmetic and skin externals using the same}

The present invention relates to a composition for improving skin diseases containing a complex extract, and a cosmetic and an external preparation for skin using the same.

Skin diseases are a general term for all diseases of the skin. Since the skin covers the surface of the body, there are many opportunities for direct contact with stimuli or various pathogens from the outside, and greatly affected by the body. Therefore, the causes of skin diseases are very diverse, and accordingly there are many kinds of diseases. Types of skin diseases include atopy, acne, eczema, spots, tumors, urticaria, rashes, blemishes, freckles, skin erosion, skin troubles, dermatitis, athlete's foot, and skin itching.

In order to improve such skin diseases, various treatment methods have been used since ancient times. For example, Korean Patent Publication No. 2010-0059188 discloses an external composition for skin using natural products, but in order to find a more effective treatment method, Research is being done. As one of the methods of treating skin diseases, cosmetics using a composition effective for skin diseases may be used. As a raw material of such cosmetics, synthetic materials or natural materials are used. However, when synthetic materials are applied to human skin for a long period of time, stability is problematic and its use is limited.

Therefore, not only can be used as a cosmetic material for improving or treating skin diseases, there have been many studies to find a natural material that can exhibit a better effect.

KR 2010-0059188 A

One object of the present invention is to provide a more effective composition for improving skin diseases.

Still another object of the present invention is to provide a cosmetic and a skin external preparation using the composition.

The present invention is mung bean, juniper fruit, licorice, horseback riding, doin, root, white, white line skin, white man, white paper, rhubarb, old book, green tea, saenghyang, golden, gold and silver, yellow baek, baekryeom, yeonkyo, yin, ginkgo biloba, upper leaf Provides a composition for improving skin diseases containing complex extracts of March, branch and casualty.

In addition, the present invention provides a cosmetic prepared using the composition.

The present invention also provides a skin external preparation prepared using the composition.

The composition containing the complex extract according to the present invention has an excellent effect on the improvement and treatment of skin diseases, it can be very useful in the preparation of cosmetics or skin external preparations for skin disease improvement.

1 is a photograph of the skin condition before using the composition of Example 1.
Figure 2 is a photograph of the skin after using the composition of Example 1 for 8 weeks.
Figure 3 is a photograph of the skin condition before using the external preparation of the skin of Example 2.
Fig. 4 is a photograph of the skin condition after using the external preparation for skin of Example 2 for 4 weeks. Fig.

Hereinafter, the present invention will be described more specifically.

The present invention is mung bean, juniper fruit, licorice, horseback riding, doin, root, white, white line skin, white man, white paper, rhubarb, old book, green tea, saenghyang, golden, gold and silver, yellow baek, baekryeom, yeonkyo, yin, ginkgo biloba, upper leaf Provides a composition for improving skin diseases containing complex extracts of March, branch and casualty.

First, each component included in the composite extract included in the composition according to the present invention will be described.

Phaseolus radiatus ) is a perennial plant of the dicotyledonous rosemary legume, which has the effect of calming the skin, shrinking the pores and clearing the skin.

The juniper fruit is also called johyeop, and the fruit of the juniper tree Dried As a herbal medicine, it is effective for treating boils, skin ulcers, constipation, and the like.

The licorice (甘草) is a perennial herb (Glycyrrhiza uralensis) belonging to the legumes (Leguminosae) and the roots or root stems of the same plant, alleviate various pains, antipyretic action, detoxification of toxic substances, etc. It is said to be effective.

The horse riding (升麻) is dried root stems of perennial herb with Buttercup Jabber, detoxification, it is known to have the effect of releasing the heat and poison of the lungs and stomach, it is used in the urticaria, rashes of the skin.

The phosphorus (桃仁) is dried in the peach seed (子 仁), remove the blood, and it is said to be effective in skin itching, drying, blemishes, freckles and the like.

The root of the tooth The root of perennial herb is called dry and it is called 'chichi', and it is said that it cools heat, releases poison, and is effective in skin disease repulsion, eczema, burns and frostbite.

The weight is the tuber of overgrown (紫 ta, Bletilla striata) As dry, it is known to have the effect of stopping blood and boosting new flesh, and can be used for hemostasis of local bleeding, and boil surgical diseases.

The ringworm (白 鮮 皮) is a dry bark of the ringworm, to remove moisture and heat in the body, it is said to be effective in eczema, boils, abscesses, skin itching.

Aconitum koreanum ), also known as yellow stone , is a perennial herb of the dicotyledonous plant of the genus Buttercup, a tuber of Aconitum koreanum R. Raymond. The rich man has no smell, tastes hot and warm. Baekbuja removes wind and phlegm and is used for facial nerve palsy, cramps, seizures, strokes, tetanus, migraine headaches, headaches and habitual quadriplegia, joint pain, scrotum, skin itching, cervical lymphadenitis, and detoxification when bitten by snakes. have.

The white paper (白芷) is to dry the roots of the billet, it is used for skin spear, skin disease, pruritus and the like.

The yellow lotus (連) is a dry root of the perennial herbaceous plant (Coptis japonica) and related plants of the genus Ranuncluaceae, it is known to have the effect of antipyretic effect, moisture removal effect, inflammation, eczema, pruritus Used for

The Gobon (藁 本) dried perennial grass roots of the mountain-type family, it is known that the anti-inflammatory effect, strong inhibitory effect against ringworm.

The green tea (綠茶) is dried tea leaves, it is known that the anti-cancer effect, inflammation inhibition, bacterial infection inhibition, antioxidant action, detoxification effect, and the like, is used in diet, skin care and the like.

The sense songhyang (甘松香) is spikenard (Nardostachys chinensis Batalin) or dried roots and roots of the same plant, known to be effective in blotch, blemishes, swelling with malnutrition, keratosis, knee edema.

The golden (芩) is the root of the perennial herbaceous golden (Scutellaria baicalensis) belonging to the Lamiaceae (Labiatae) and dried relatives, the taste is bitter, has a cold nature, moisture removal, heat removal, etc. It is known that this is.

The gold and silver (金 銀花) is a honeysuckle ( Lonicera) japonica Thunberg) or its buds are dried and are known to be effective in boils, skin toxins, heat poisoning due to heat poisoning, and swelling.

The baekbaek (柏) is a bark of the yellow bark as a dry, to remove moisture, soothing a lot of heat, it is known to be effective in eczema and pruritus.

The baekryeom (白 斂) is a deciduous non-fertility plant belonging to the grape family, the scientific name Ampelopsis japonica. It is MAKINO, and it is also called white root, white vine, salt, and ash chain. The name Kahoe saw originated from the shape of a saw, with the leaves splitting into idols. Its root is used as a herbal medicine, and is used for anti-inflammatory, analgesic, or surgical inflammatory treatments such as boils, dermatitis, otitis media, burns, or swelling.

The Yeongyo (連翹) is dried fruit of forsythia, known to have the effect of antipyretic action, detoxification, etc., is used for skin rash, boil, single, etc. caused by acute febrile infectious diseases.

The wood is a dry bark of the wood, also called Haedongpi (海桐 皮), removes the custom, has the effect of passing through the meridians, and is known to be effective even if the waist or knee is cold and tingling, eczema, skin diseases, etc. Is also used.

The ginkgo leaves are dried leaves of ginkgo biloba, and are known to be good for heart and blood clots, and to be effective in blood vessels and blood flow disorders.

The upper leaf (桑葉) is dried leaves of the mulberry, it is known to have the effect of removing the heat of the human body, reducing the heat of the liver, and is effective in skin urticaria and the like.

The gusset is purslane with purslane ( Portulaca oleracea L.) is known to be effective in antipyretic, detoxification, etc., and is used to improve dryness, athlete's foot, eczema, and boils.

The branch (地膚 子) is dried seed of Dapsari, is known to be effective in moist heat of the skin, it is used to improve pruritus, eczema and the like.

The casualty (蛇床子) is dried fruit of the biennial herb of the dicotyledonous plant Asteraceae, has a bactericidal effect and is used for skin pruritus, eczema, allergic dermatitis, and ulcers.

The cosmetic composition for improving skin diseases of the present invention is characterized in that it contains a complex extract obtained by mixing and extracting the 25 kinds of medicinal herbs as an active ingredient.

Here, the 25 kinds of medicines are defined as 'raw material of the complex extract'. In addition, the following weight percent is based on the total weight of solids of the raw material of the composite extract.

At this time, the mung bean is preferably contained in 3 to 40% by weight based on the total weight of the raw material of the composite extract, the juniper fruit is contained in 3 to 40% by weight relative to the total weight of the raw material of the composite extract It is preferable.

The licorice is preferably contained in 3 to 40% by weight relative to the total weight of the raw material of the composite extract, the horse riding is preferably included in 3 to 40% by weight relative to the total weight of the raw material of the composite extract.

Preferably, the phosphorus is included in an amount of 2 to 30% by weight based on the total weight of the raw material of the composite extract, and the roots are preferably included in an amount of 2 to 30% by weight based on the total weight of the raw material of the composite extract. It is preferable to include 2 to 30% by weight based on the total weight of the raw material of the silver composite extract, the white skin is preferably contained in 2 to 30% by weight based on the total weight of the raw material of the composite extract, the white rich is complex It is preferably included in 2 to 30% by weight relative to the total weight of the raw material of the extract.

The white paper is preferably contained in 1 to 20% by weight based on the total weight of the raw material of the composite extract, the sulfur is preferably contained in 3 to 40% by weight relative to the total weight of the raw material of the composite extract, It is preferably included in 1 to 20% by weight relative to the total weight of the raw material of the silver composite extract, the green tea is preferably included in 1 to 20% by weight relative to the total weight of the raw material of the composite extract.

It is preferable that the persimmon aroma is included in an amount of 2 to 30% by weight based on the total weight of the raw material of the composite extract, and the golden silver is preferably contained in an amount of 3 to 40% by weight based on the total weight of the raw material of the composite extract. Gold and silver is preferably included in 2 to 30% by weight based on the total weight of the raw material of the composite extract, the sulfur white is preferably included in 3 to 40% by weight relative to the total weight of the raw material of the composite extract.

The baekryeom is preferably included in 3 to 40% by weight relative to the total weight of the raw material of the composite extract, the duct bridge is preferably included in 1 to 20% by weight relative to the total weight of the raw material of the composite extract, Is preferably contained in 2 to 30% by weight relative to the total weight of the raw material of the composite extract, the ginkgo leaves are preferably included in 1 to 20% by weight based on the total weight of the raw material of the composite extract.

The upper leaf is preferably included in 1 to 20% by weight relative to the total weight of the raw material of the composite extract, the gusset is preferably included in 1 to 20% by weight relative to the total weight of the raw material of the composite extract, The ruler is preferably included in an amount of 1 to 20% by weight based on the total weight of the raw material of the composite extract, the casualty is preferably included in 1 to 20% by weight relative to the total weight of the raw material of the composite extract.

When the components are used as a raw material of the composite extract in the above content, the obtained composite extract can exhibit the desired efficacy in the present invention.

In addition, the complex extract is preferably contained in 5 to 50% by weight relative to the total weight of the composition.

Skin diseases in which the compositions of the present invention can be used include, but are not limited to, atopy, acne, skin erosion, skin troubles, blemishes, freckles, eczema, athlete's foot, dermatitis, skin itching, and the like.

The skin erosion refers to a defect in the surface of the skin or mucous membrane, and often occurs in the place of small blisters or pus due to dermatitis or fistula, burns, traumas, etc. It is a symptom that can progress to.

The composition of the present invention has an excellent effect on the improvement and treatment of skin diseases, it can be very useful as a raw material of the cosmetic for improving skin diseases.

The composition of the present invention may comprise one or two or more selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, polymer peptides, polymer polysaccharides, sphingolipids, and seaweed extracts as additional compounding ingredients. However, the compounding component which may be further included in the cosmetic and external skin composition of the present invention is not limited thereto.

In addition, the cosmetic composition of the present invention may include components conventionally used in the cosmetic composition in addition to the additional blending components, specific examples of such components are stabilizers, solubilizers, vitamins, pigments, flavors, diluents, carriers, humectants Etc., but is not necessarily limited thereto. The said component can be mix | blended within the range which does not impair the objective and effect of this invention.

On the other hand, the complex extract of the present invention may be obtained by extracting after mixing the 25 kinds of medicinal herbs, or may be obtained by mixing after preparing each medicinal extract.

Specific examples of the production method of the composition of the present invention are as follows, but are not necessarily limited to the following method.

The complex extract contained in the composition of the present invention may be prepared by putting the 25 kinds of medicinal herbs in a solvent, extracting by applying heat for 1 to 6 hours at a temperature of about 80 ℃ to 140 ℃, and then concentrated it .

Here, the solvent is a polar solvent such as purified water, water, methanol, ethanol, butanol; And non-polar solvents such as hexane, glycerin, chloroform, ethyl acetate, and the like, but may be used, but is not limited thereto.

The present invention provides a cosmetic prepared using the composition.

Cosmetics produced using the composition of the present invention may take the form of solutions, emulsions, viscous mixtures and the like.

The cosmetic composition of the present invention may be prepared in any formulation commonly prepared in the art, for example, latex, cream, lotion, pack, foundation, lotion, essence, hair cosmetic and the like. Specific examples of the cosmetic of the present invention include skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisturizing lotion, nutrition lotion, massage cream, nutrition cream, moisturizing cream, hand cream, foundation, essence, pack, soap, Cleansing foam, cleansing lotion, cleansing cream, body lotion, body cleanser and the like, but is not limited thereto.

The present invention also provides a skin external preparation prepared using the composition.

The external preparation for skin of the present invention may be applied to the human body in various ways or forms, but preferably it can be formulated into a topical external application form applied topically to the skin. For example, powders, ointments, gels, creams, linings, lotions, liquids, or aerosols, but are not limited thereto.

When formulated with the external preparation for skin, additives and the like can be appropriately formulated in addition to the composition of the present invention. The additives are commonly used in the art, and can be blended within the scope of not impairing the object and effect of the present invention.

Hereinafter, the present invention will be described in more detail with reference to Examples. The following examples are intended to illustrate the invention but do not limit the scope of the invention.

< Example  1> Preparation of a composition for improving skin diseases

Each raw material was weighed and mixed as follows.

Mung bean 800g, juniper fruit 800g, licorice 800g, ringworm 800g, horse riding 400g, doin 400g, root 400g, white weight 400g, white man 400g, white paper 400g, rhubarb 400g, original 400g, golden 400g, yellow white 400g, white rye 400g, yeonkyo 400g , 400g green tea, 200g green tea, 200g persimmon incense, 200g gold and silver coin, 200g ginkgo biloba, 200g upper leaf, machi 200g, branch 200g, casualty 200g

After washing the mixed raw materials in clean running water, put the mixed raw materials in a high-pressure extractor, poured 7 times purified water, and heated to 97 ℃. After 1 hour, the temperature was increased to 109 ° C., and after 30 minutes, water vapor was discharged three times every 15 minutes to obtain a liquid extract. The liquid extract was filtered using a cotton mesh of 300 mesh, then aged for 3 days at 7 ~ 15 ° C to obtain a final extract.

The mung bean was well dried with seeds of the fruit of the perennial herb of the dicotyledonous rosemary legume was used to pick out the malformed grain and foreign matter. The juniper fruit was used as a flat and slightly bent bean pod shape and foreign matters. The licorice was dried by peeling a portion of the stem with a peeled 2mm thick. The horse riding was used as the horsetail of the Cannabis family (Cimicifuga heracleifolia Komarov) or the root stem of the same plant, washed thoroughly with water and dried and then sliced to 2-3mm. The cabbage was dried well with Prunus persica Batsch seeds. The root root was a root stem of perennial herb of the dicotyledon plant calliphytic plant, washed with water, dried and cut into 3 cm. The white rat was used to wash the tubers of the orchid family (Bletilla striata (Thunberg) Reichenbach fil.) Washed with water, dried and cut into appropriate sizes. The ringworm was used to wash the roots of ringworm (Dictamnus dasycarpus Turcz.) With water and then peeled and dried finely peeled. The white man was washed with water and then chopped a tuber of Aconitum koreanum R. Raymond of the buttercup family. The white paper was used to thinly wash the roots of Angelica dahurica Bentham et Hooker washed with water and dried. The rhubarb used to wash the roots of the perennial herbaceous plant (Coptis Chinensis FRANCH) belonging to the buttercup family, washed with water and dried finely. The Gobon was used by thinly drying the root stem of Angelica tenuissima Nakai, which is a perennial herb of the dicotyledonous plant Asteraceae. The green tea was used by picking the young leaves of the evergreen arboretum of the dicotyledonous plant stem membrane tea tree. The persimmon scent was used to cut the root stems of persimmon (Nardostachys chinensis Batalin) or the same plant with water, dried and cut short. The golden was used to cut the roots of Scutellaria baicalensis GEORGE of perennial herbaceous plants belonging to the Lamiaceae, washed with water and dried to a certain size. The gold and silver coins were used after picking the buds of the Lonera japonica Thunberg. The baekbaek was used to cut a bark from the tree trunk of the deciduous shrub Phellodendron amurense belonging to the Unhyang family and dried to a certain size. The baekryeom was used to cut the roots of the deciduous vine stem belonging to the family Ampelopsis japonica. The duct was dried by picking the mature fruit of the forsythia viridissima Lindley or Forsythia suspensa Vahl. The Yin-Mak was used to cut tree trunks of Yin-Mak or Kalopanax pictus, which is a deciduous tree of the dicotyledonous plant, Arboraceae. The ginkgo leaves were dried and picked from the mature leaves of Ginkgo biloba L., a deciduous tree belonging to the genus Ginkgo biloba. The upper leaves were dried by picking mature leaves of the mulberry (Morus alba L.) which is a deciduous tree belonging to the mulberry family. The gusset was used to dry the outpost of purslane (Portulaca oleracea L.) with purslane. The locust broth was dried after the mature fruit of Kochia scoparia Scharder, an annual herb of the mackerel. The casualties were dried after the mature fruit of Torilis japonica Decandolle, a biennial paste of the dicotyledonous plant.

< Example  2> External skin preparations  Produce

50 liters of purified water was put into this kiln, and it heated at 60 degreeC. Then, 50 liters of purified water was added to a separate kiln, 2 kg of Aloe (aloe), 2 kg of Sodium Hyaluronate (hyaluronic acid), 2 kg of Allantoin (alantoin), and 25 kg of Betaine (betaine) were completely dissolved, and then put into the kiln. Subsequently, 50 liters of the composition of Example 1 and 10 kg of Beta-Glucan (betaglucan) were added and dissolved in a separate kiln, and then put into the kiln. Subsequently, the remaining amount of purified water and the thickener 2kg were put in a separate kiln and sufficiently dissolved, and then put into the kiln. Subsequently, 10 kg of nanolipophilic Ceramide 3 (ceramide) was added to the kiln. Subsequently, 13 kg of an emulsifier, 2 kg of an auxiliary emulsifier, 10 kg of a natural preservative, and an appropriate amount of fragrance were added to the kiln and then dissolved in a sufficient amount, and then put into the kiln. Subsequently, the raw materials put into the kiln are mixed with the remaining amount of purified water while maintaining 60 ° C, and then dissolved at 4 rpm for more than 4 hours at 15 rpm rotation. Was prepared.

< Experimental Example  1> Acne  Confirmation of dermatitis improvement effect

50-acne patients aged 12-32 years old using the composition of Example 1 was applied twice a day for 8 weeks morning and evening to the affected area to confirm the improvement effect of acne dermatitis. Evaluation of the effect was used acne improvement effect evaluation method (Local SCORAD) before and after using the composition of Example 1.

The clinical evaluation included (1) Hyperpigmentation, (2) Pustule acne, (3) Cyst acne, and (4) Papule acne. Was performed.

According to the improvement of acne dermatitis, it was evaluated in 5 stages (0 = no symptoms, 1 = some symptoms, 2 = half of symptoms, 3 = lots of symptoms, 4 = is the same), Clinical Evaluation The total values of all four items were evaluated. The total improvement rate for each individual is calculated by subtracting the total 4 items after use and subtracting the total of 4 items after use (Equation 1), and the average improvement rate per person (% / person) is calculated by dividing the total of individual improvement rates by the number of subjects. One thing (Equation 2) is shown in Table 1 below.

< Equation  1>

% Improvement = (Score of 4 items before use-Total score of 4 items after use)

                 ÷ Total score of 4 items before use × 100

< Equation 2>

Average improvement rate per person (%) = Total improvement rate (%) ÷ Number of people (person)

sample Item Total improvement rate Target number Average improvement rate per person (%) Example 1 Hyperpigmentation 1525 20 76.25 Example 1 Purulent acne 325 5 65 Example 1 Cystic acne 675 10 67.5 Example 1 Papular acne 1075 15 71.67

From the results of Table 1, it can be seen that the composition of Example 1 has an excellent effect of improving acne dermatitis. Twelve people who used the composition of Example 1 for dying or perm on the scalp-like itchy scalp for one week were reported to have improved their symptoms. Eighteen out of 50 patients using the composition of Example 1 were reported to have improved symptoms as a result of eczema, tumors, rashes, blemishes, freckles, skin erosions, skin problems, dermatitis, and skin itch. Twelve of the 50 people who used the composition of Example 1 were used in the same manner until further cured for 6-8 weeks, and after 3 months of cured, the recurrence or side effects of acne were investigated, but there was no problem. It was investigated. One out of 50 patients using the composition of Example 1 was photographed before and after 8 weeks of use. 1 is a photograph of the skin condition before using the composition of Example 1, Figure 2 is a photograph of the skin condition after using the composition of Example 1 for eight weeks. As a result, it can be seen visually that acne is effectively improved in using the composition of Example 1. In conclusion, it was confirmed that the composition of the present invention is effective for acne of various symptoms and there is no problem of recurrence or side effects.

< Experimental Example  2> Confirmation of atopic dermatitis improvement effect

The topical skin preparation of Example 2 was treated twice daily (morning and evening) for 120 atopic dermatitis patients (aged 2 to 60 years old), such as skin erythema, pruritus (itch) and dry skin. Experiments were conducted to confirm the improvement effect of atopic dermatitis by using for 4 weeks while applying to the site. As for the effect evaluation, the atopic improvement effect evaluation method (Local SCORAD) was used before and after using the external preparation for skin of Example 2.

Clinical evaluation includes (1) Erythema, (2) Xeroderma, (3) Pruritus Cutaneous, (4) Exudation, (5) Lichenification, and (6) Keratolysis was performed on a total of six items.

According to the improvement of atopic dermatitis, it was evaluated in five stages (0 = no symptoms, 1 = some symptoms, 2 = half symptoms, 3 = a lot of symptoms, 4 = the symptoms remain), Clinical Evaluation The total values of all six items were evaluated. The sum of six item scores before use was subtracted from the sum of six item scores after use (%) (Equation 3), and the average improvement rate per person (% / person) was calculated by dividing the total of individual improvement rates by the number of subjects. (Equation 4) is shown in Table 2 below.

< Equation  3>

% Improvement = (Score of 4 items before use -Score of 4 items after use)

÷ Total score of 4 items before use × 100

< Equation  4>

Average improvement rate per person (%) = total improvement rate ÷ number of persons

sample Item Improvement total Target number Average improvement rate per person (%) Example 2 Skin erythema 1,575 20 78.75 Example 2 Dry skin 1,725 20 86.25 Example 2 Skin pruritus 1,775 20 88.75 Example 2 Effusion 1,450 20 72.5 Example 2 Taesun 1,350 20 67.5 Example 2 Epidermal detachment 1,650 20 82.5

From the results of Table 2, it can be seen that the external preparation for skin of Example 2 has an excellent effect of improving atopic dermatitis.

External skin preparation of Example 2. 16 people who used it for 3 days on heat, hot and itchy red skin exposed to the sun were getting better and 3 people who used it for 1 week on the skin damaged by laser surgery reported that the skin disappeared, calmed down and improved to normal skin. .

Ten of the 120 people who used the external preparation of Example 2 were used in the same manner until they were cured for an additional 4 weeks, and after 3 months of treatment, the recurrence or side effects of atopic dermatitis were examined, but there was no problem. It was investigated. One of the subjects using the external preparation for skin of Example 2 was photographed before and after 4 weeks of use. 3 is a photograph of the skin condition before using the topical skin preparation of Example 2, Figure 4 is a photograph of the skin condition after using the topical skin preparation of Example 2 for four weeks. As a result, it can be confirmed visually that atopic dermatitis is effectively improved by using the external preparation for skin of Example 2.

In conclusion, it has been confirmed that the external preparation for skin of the present invention is effective for various atopic dermatitis and has no problem of recurrence or side effects.

Claims (7)

Mung bean, apricot tree fruit, licorice, horseback riding, cinnabar root, white root, white pine, white rich man, white paper, yellow lotus, old book, green tea, saenghyanghyang, golden, gold and silver, yellow white, baekryeom, yeonkyo, yin, ginkgo leaf, upper leaf, machi, A composition for improving skin diseases containing complex extracts of branch and casualty. The method according to claim 1, wherein the composite extract is based on the total weight of the raw material of the composite extract 3 to 40% by weight, 3 to 40% by weight of juniper berries, 3 to 40% by weight licorice, 3 to 40% by weight, horse riding 2 to 30% by weight, roots 2 to 30% by weight, white to 2 to 30% by weight, white skin 2 to 30% by weight, white tofu 2 to 30% by weight, white paper 1 to 20% by weight, rhubarb 3 to 40% by weight 1 to 20% by weight, green tea 1 to 20% by weight, persimmon fragrance 2 to 30% by weight, golden 3 to 40% by weight, gold and silver coins 2 to 30% by weight, yellow and white 3 to 40% by weight, baekryeom 3 to 40% by weight, soft bridge 1 to 20% by weight, 2 to 30% by weight of ginkgo biloba, 1 to 20% by weight of ginkgo biloba, 1 to 20% by weight of upper leaves, 1 to 20% by weight of machi, 1 to 20% by weight of branch and 1 to 20% by weight of casualty A composition for improving skin diseases, which is prepared by extracting it from raw materials. The method according to claim 1,
The complex extract is a composition for improving skin diseases, characterized in that contained in 5 to 50% by weight based on the total weight of the composition. The method according to claim 1,
The skin disease is atopic dermatitis, acne, blemishes, freckles, skin erosion, skin troubles, eczema, athlete's foot, dermatitis or skin itching composition, characterized in that for improving the skin disease. Mung bean, apricot tree fruit, licorice, horseback riding, cinnabar root, white root, white pine, white rich man, white paper, yellow lotus, old book, green tea, saenghyanghyang, golden, gold and silver, yellow white, baekryeom, yeonkyo, yin, ginkgo leaf, upper leaf, machi, Cosmetic composition for improving skin diseases containing a complex extract of the branch and casualty as an active ingredient. Cosmetic preparation prepared using the composition according to any one of claims 1 to 4. An external preparation for skin prepared using the composition according to any one of claims 1 to 4.

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