CN103494924A - Chinese medicine composition for treating damp-heat stagnation acne - Google Patents

Abstract

The invention discloses a Chinese medicine composition for treating damp-heat stagnation acne. The Chinese medicine composition is prepared from thalictrum aquilegifolium, herba andrographitis, adnate cudweed, cortex dictamni, common pearleverlasting herb, honeysuckle, ailanthus altissima swingle, rhizoma atractylodis, golden cypress and dichondra repens. The Chinese medicine composition can be clinically applied to treatment of the damp-heat stagnation acne.

Description

A kind of Chinese medicine composition for the treatment of damp and hot pent-up type acne

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of damp and hot pent-up type acne.

Background technology

Acne is commonly called as " comedo ", is a kind of chronic struvite pilosebaceous unit disease, is also one of more common disease of department of dermatologry clinically.Acne is mainly in teenager, and relevant report claims the nearly 80-90% patients with acne age at 14-25 between year, and it is middle age that small number of patients is also arranged.Acne is mainly sent out in face, and the many places such as also be everlasting chest and back occur, not only affect the healthy of patient, are also having a strong impact on patient's mental health and quality of life, and therefore curing acne in time is the fervent serious hope of patient.Treated damp and hot pent-up type acne single western medicine therapy commonly used, but effect is not satisfactory in the past, draws through inventor's long-term practice, Chinese medicine is controlled damp and hot pent-up type acne and is had better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide the Chinese medicine composition of the damp and hot pent-up type of the treatment acne that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Thalictrum aquilegifolium L. var. sibiricum Regel, Herba Andrographis, Herba Gnaphalii Adnati, Cortex Dictamni, Herba Anaphalidis Margaritaceae, Flos Lonicerae, Fructus Ailanthi, Rhizoma Atractylodis, Cortex Phellodendri, Herba Dichondrae Repentis according to certain compatibility requirement, through being processed into.

Prepare Chinese medicine composition of the present invention and make Thalictrum aquilegifolium L. var. sibiricum Regel 20-30 part, Herba Andrographis 20-30 part, Herba Gnaphalii Adnati 20-30 part, Cortex Dictamni 10-20 part, Herba Anaphalidis Margaritaceae 10-20 part, Flos Lonicerae 10-20 part, Fructus Ailanthi 10-20 part, Rhizoma Atractylodis 10-20 part, Cortex Phellodendri 10-20 part, Herba Dichondrae Repentis 5-10 part by following raw material medicaments.

Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 25 parts of Thalictrum aquilegifolium L. var. sibiricum Regel, 25 parts of Herba Andrographis, 25 parts of Herba Gnaphalii Adnatis, 15 parts of Cortex Dictamni, 15 parts of Herba Anaphalidis Margaritaceaes, 15 parts of Flos Loniceraes, 15 parts of Fructus Ailanthi, 15 parts of Rhizoma Atractylodis, 15 parts of Cortex Phellodendris, 8 parts of Herba Dichondrae Repentiss.

The pharmacological action of Chinese medicine of the present invention is as follows:

Thalictrum aquilegifolium L. var. sibiricum Regel: bitter, cold.GUIXIN, liver, large intestine channel.Clearing away heat-fire, the dampness removing toxic substances.Clinical vexed for calentura, hygropyretic dysentery, cough due to lung-heat, conjunctival congestion and swelling pain, carbuncle furuncle.

Herba Andrographis: bitter, cold.GUIXIN, lung, large intestine, urinary bladder channel.Heat-clearing and toxic substances removing, pathogenic fire purging, dampness.Clinical in anemopyretic cold, epidemic febrile disease heating, cough due to lung-heat, pertussis, lung abscess, laryngopharynx swelling and pain, jaundice due to damp-heat, stranguria, erysipelas, skin infection carbuncle, eczema, venom etc.

Herba Gnaphalii Adnati: bitter, cold.Heat clearing and damp drying, detoxicating and resolving stagnation of pathogens, hemostasis.Clinical in hygropyretic dysentery, detoxicating and resolving stagnation of pathogens, the diseases such as hemostasis.Cortex Dictamni: bitter, cold, return spleen, stomach warp.Heat clearing and damp drying, the removing toxic substances of dispeling the wind.Outward for herpes simplex poison, eczema scabies.

Herba Anaphalidis Margaritaceae: bitter, hot, cool.Clearing away heat-fire, dampness, anthelmintic.For toothache, damp-heat dysentery, ascariasis, the diseases such as scrofula.

Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.For carbuncle furuncle, toxic-heat and blood stasis.

Fructus Ailanthi: bitter, puckery, cool.Heat clearing and damp drying, dysentery relieving, hemostasis.Clinical in dysentery, nebulousurine, leukorrhagia, have blood in stool, hematuria, the diseases such as metrorrhagia.

Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach warp.Drying damp and strengthening spleen, wind-damp dispelling.For the burnt card of humidity hysteresis, the rheumatism arthromyodynia, affection of exogenous wind-cold is held wet exterior syndrome under the arm.

Cortex Phellodendri: bitter, cold.Return kidney, urinary bladder channel.Heat clearing and damp drying, eliminating fire and detoxication.Cure mainly hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema.

Herba Dichondrae Repentis: bitter, hot, cool.Return lung, Liver Channel.Heat clearing away, dampness removing, removing toxic substances.Clinical in jaundice, dysentery, nebulousurine, edema, furuncle swelling toxin, the diseases such as traumatic injury.

By eating and drinking without temperance, the thing of the pungent delicious food savoury of surfeit, help humidogene heat, makes the gastrointestinal intrinsic heat, and accumulated heat follows the large intesting channel of Hand-Yangming and the stomach channel of foot-Yang-ming is up in face, strongly fragrantly in pore, causes acne.Control the heat clearing and damp drying pathogenic fire purging to be main.Thalictrum aquilegifolium L. var. sibiricum Regel clearing away heat-fire, dampness removing toxic substances, Herba Andrographis heat-clearing and toxic substances removing, pathogenic fire purging, dampness, Herba Gnaphalii Adnati dampness, detoxicating and resolving stagnation of pathogens in the present invention, for monarch drug, Cortex Dictamni heat clearing away, dampness, Herba Anaphalidis Margaritaceae heat clearing away, pathogenic fire purging, dampness, Flos Lonicerae clearing away heat-fire, the Fructus Ailanthi heat clearing and damp drying, Rhizoma Atractylodis are drying damp and strengthening spleen, Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, Herba Dichondrae Repentis dampness removing, removing toxic substances.Through clinical practice, find, damp and hot pent-up type acne is had to unique curative effect, and all medicines are played the effect of heat-clearing and toxic substances removing, dampness pathogenic fire purging altogether, reach the purpose of the damp and hot pent-up type acne for the treatment of.

Chinese medicine composition of the present invention was in 2006 to 2012 the damp and hot pent-up type of clinical observation acne 124 routine patients, and clinical report is as follows:

1, physical data

In 124 routine patients, age 17-30 year, the course of disease is many at 3 months to 2 years, 23 years old mean age.

2, diagnostic criteria

2.1 " traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:

1. the initial stage presents the red pimple of grain of rice size at follicular orifice, also can develop into pustule, after this can form hoary hair's acne or the blackhead of scleroma sample, and serious case can form scleroma property cyst;

2. be mainly in young men and women's adolescence, be distributed in face and chest and back, often with seborrhea;

3. have the thick greasy or exopathogen of eating and drinking without temperance, surfeit delicious food etc. to bring out more;

4. the women is many with menoxenia.

Clinical manifestation: be more common in teenager, be apt to occur in face amount, forehead, visible pimple, pustule, cyst etc., the face light is greasy, doublely sees the xerostomia desire for cold drinks, halitosis, diet is more, yellow urine, constipation, red tongue, yellow fur or yellow greasy, slippery and rapid pulse.

2.2 inclusive criteria:

1. 11～30 years old age; 2. meet the diagnostic criteria of the damp and hot pent-up type of homeliness type acne; 3. observe in first 4 weeks and do not use the Chinese and western drugs relevant with primary disease; 4. the patient agrees to participate in voluntarily, and can coordinate clinical observation.

2.3 exclusion standard:

1. known to the Viaminate allergy sufferers; 2. enter to try the first 2 weeks once heat resistance pent-up type acne medicine persons such as external corticosteroid hormone, antibiotic; 3. enter to try first 4 weeks once oral corticosteroid hormone, gonadal hormone, antibiotic medicine persons; 4. gestation or women breast-feeding their children; 5. the damp and hot pent-up type of the occupational due to chemical substance acne, drug-induced damp and hot pent-up type acne.

3, Therapeutic Method

3.1 prescription: Thalictrum aquilegifolium L. var. sibiricum Regel 25g, Herba Andrographis 25g, Herba Gnaphalii Adnati 25g, Cortex Dictamni 15g, Herba Anaphalidis Margaritaceae 15g, Flos Lonicerae 15g, Fructus Ailanthi 15g, Rhizoma Atractylodis 15g, Cortex Phellodendri 15g, Herba Dichondrae Repentis 8g.

3.2 method of preparation and use: said medicine technique is routinely made decoction, 1 dose of every day, every day 2 times, within 7 days, is 1 course for the treatment of.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Recovery from illness: skin lesion extinction rate >=95%, or only leave over a little pigmentation, transference cure;

Produce effects: the skin lesion major part disappears, extinction rate 70%～95%, and symptom obviously alleviates;

Effectively: skin lesion partly disappears, extinction rate 50%～70%, doing well,improving;

Invalid: skin lesion disappears not obvious or increases the weight of, extinction rate<50%, and symptom has no variation.

4.2 result: in 124 routine patients, clinical cure 65 examples (52.3%), produce effects 30 examples (24.2%), 21 examples that take a turn for the better (16.9%), invalid 8 examples (6.4%), total effective rate is 93.6%.

Model case

1, Zhang, the man, 21 years old, the skin oil and fat secretion was vigorous, the intensive a plurality of pimple pustules of buccal section, forehead, lower jaw also have a little lesser tubercle, suffer from constipation simultaneously, the symptoms such as mouth and nose drying, halitosis.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.

2, Lee, the female, 18 years old, face was greasy, corse sweat pore, face is except nose and eye, and all red color visible or pale red pimple, can extrude white lead color grease, and greater tubercle is extruded with thin purulence and courageous and upright secretions, red tongue, yellow fur or yellow greasy, slippery and rapid pulse.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.

3, Liu, the man, 23 years old, suffer from acne existing for many years, buccal section acne merges in flakes, and color is red, and there is pustule tip, red tongue, yellow and thin fur, the floating-rolling pulse number, with symptoms such as constipation.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.

The specific embodiment

Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.

Embodiment 1, a kind of Chinese medicine composition for the treatment of damp and hot pent-up type acne is to be made by Thalictrum aquilegifolium L. var. sibiricum Regel 20g, Herba Andrographis 20g, Herba Gnaphalii Adnati 20g, Cortex Dictamni 10g, Herba Anaphalidis Margaritaceae 10g, Flos Lonicerae 10g, Fructus Ailanthi 10g, Rhizoma Atractylodis 10g, Cortex Phellodendri 10g, Herba Dichondrae Repentis 5g.

Embodiment 2, a kind of Chinese medicine composition for the treatment of damp and hot pent-up type acne is to be made by Thalictrum aquilegifolium L. var. sibiricum Regel 25g, Herba Andrographis 25g, Herba Gnaphalii Adnati 25g, Cortex Dictamni 15g, Herba Anaphalidis Margaritaceae 15g, Flos Lonicerae 15g, Fructus Ailanthi 15g, Rhizoma Atractylodis 15g, Cortex Phellodendri 15g, Herba Dichondrae Repentis 8g.

Embodiment 3, a kind of Chinese medicine composition for the treatment of damp and hot pent-up type acne is to be made by Thalictrum aquilegifolium L. var. sibiricum Regel 30g, Herba Andrographis 30g, Herba Gnaphalii Adnati 30g, Cortex Dictamni 20g, Herba Anaphalidis Margaritaceae 20g, Flos Lonicerae 20g, Fructus Ailanthi 20g, Rhizoma Atractylodis 20g, Cortex Phellodendri 20g, Herba Dichondrae Repentis 10g.

Claims (2)

1. a Chinese medicine composition for the treatment of damp and hot pent-up type acne is characterized in that it is to be made by following raw material medicaments:

Thalictrum aquilegifolium L. var. sibiricum Regel 20-30 part, Herba Andrographis 20-30 part, Herba Gnaphalii Adnati 20-30 part, Cortex Dictamni 10-20 part, Herba Anaphalidis Margaritaceae 10-20 part, Flos Lonicerae 10-20 part, Fructus Ailanthi 10-20 part, Rhizoma Atractylodis 10-20 part, Cortex Phellodendri 10-20 part, Herba Dichondrae Repentis 5-10 part.

2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:

25 parts of Thalictrum aquilegifolium L. var. sibiricum Regel, 25 parts of Herba Andrographis, 25 parts of Herba Gnaphalii Adnatis, 15 parts of Cortex Dictamni, 15 parts of Herba Anaphalidis Margaritaceaes, 15 parts of Flos Loniceraes, 15 parts of Fructus Ailanthi, 15 parts of Rhizoma Atractylodis, 15 parts of Cortex Phellodendris, 8 parts of Herba Dichondrae Repentiss.