CN114668695B

CN114668695B - Anti-dandruff composition, shampoo containing anti-dandruff composition and preparation method of shampoo

Info

Publication number: CN114668695B
Application number: CN202210304603.5A
Authority: CN
Inventors: 刘伟平
Original assignee: Guangzhou Jinxiang Cosmetics Co ltd
Current assignee: Guangzhou Jinxiang Cosmetics Co ltd
Priority date: 2022-03-26
Filing date: 2022-03-26
Publication date: 2023-01-20
Anticipated expiration: 2042-03-26
Also published as: CN114668695A

Abstract

The invention relates to the field of cosmetics, and particularly discloses an anti-dandruff composition, shampoo containing the anti-dandruff composition and a preparation method of the shampoo. Wherein the anti-dandruff composition comprises the following components: ammonium laureth sulfate; decyl glucoside; hydrolyzing jojoba esters; dimethiconol; gentian extract; extract of gentiana macrophylla; herba Swertiae Bimaculatae extract. The shampoo containing the anti-dandruff composition comprises the following components: an anti-dandruff composition; acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer; polyethylene glycol-12; a thickener; a foam booster; a preservative; a softening agent; a chelating agent; a pH adjusting agent; and (3) water. The preparation method comprises the following steps: mixing the components in sequence to obtain shampoo containing the anti-dandruff composition. The composition has the advantage of long-lasting anti-dandruff effect; in addition, the preparation method of the invention also has the advantages of simple and convenient preparation and easy industrial production.

Description

Anti-dandruff composition, shampoo containing anti-dandruff composition and preparation method of shampoo

Technical Field

The invention relates to the field of shampoo, in particular to an anti-dandruff composition, shampoo containing the anti-dandruff composition and a preparation method of the shampoo.

Background

Shampoos, also known as shampoos and shampoos, are the most widely used hair washing products, and are also one of the most commonly used hair cosmetics, and are mainly used for washing off fats and oils, sweat scales, cells exfoliated from the scalp, foreign dust, microorganisms, residues of styling products, bad smells, etc., which are attached to the hair in decimetre, thereby keeping the scalp and the hair clean and beautiful.

Among them, the anti-dandruff effect is one of the most concerned effects among the effects of the existing shampoos, and the anti-dandruff effect of the existing shampoos is generally realized by adding surfactants with stronger cleaning power. However, the surfactant having a strong cleansing power can only remove dandruff strongly during hair washing, so that the amount of dandruff after the hair is washed is reduced, but in daily life, keratinocytes of the scalp are continuously exfoliated and dandruff is continuously generated, so that the dandruff removing effect can only maintain a good effect for a short time, and the state of low amount of dandruff of the hair cannot be maintained continuously. Thus, there is still room for improvement.

Disclosure of Invention

In order to improve the long-acting and lasting anti-dandruff effect of the shampoo, the application provides an anti-dandruff composition, the shampoo containing the anti-dandruff composition and a preparation method.

In a first aspect, the present application provides an anti-dandruff composition, which adopts the following technical scheme:

an anti-dandruff composition comprises the following components in parts by mass:

8-12 parts of ammonium laureth sulfate;

decyl glucoside 0.3-0.7 parts;

0.1-0.3 part of hydrolyzed jojoba esters;

0.7-1.2 parts of dimethiconol;

0.2-0.5 parts of gentian extract;

0.1-0.3 parts of gentiana macrophylla extract;

0.1-0.3 part of swertia extract.

By adding the ammonium laureth sulfate and the decyl glucoside, the oil removal, stain removal and dandruff removal capabilities of the dandruff removing composition can be better improved, the instant dandruff removing effect of the dandruff removing composition is better, and dandruff is less likely to remain on hair after cleaning; through adding hydrolysis jojoba esters and dimethiconol, be favorable to improving the nourishing effect of antidandruff composition better, thereby make the scalp be difficult to because the cleaning power of laureth ammonium sulfate and decyl glucoside is too strong and the dry condition appears, be favorable to the scalp to be in moist state all the time after the hair is washd and is accomplished, and then be favorable to reducing the drop of scalp stratum corneum better, be favorable to suppressing the lasting production of dandruff better, and simultaneously, still make the hair be difficult to appear frizzy owing to too dry more, knot, the condition of branching.

The gentiana scabra bunge extract, the gentiana macrophylla extract and the swertia davidi extract are added for synergistic compounding, so that the growth of the dandruff spore bacteria is favorably inhibited, the dandruff spore bacteria are more difficultly bred on the scalp, the pathological dandruff is favorably reduced, and the dandruff removing effect of the dandruff removing composition is more lasting and long-acting; meanwhile, the gentiana scabra bunge extract, the gentiana macrophylla bunge extract and the swertia davidii extract are also beneficial to better conditioning the scalp, so that the water and oil of the scalp are more balanced, the scalp is more difficult to excessively produce oil due to the nourishing of hydrolyzed jojoba esters and dimethiconol, the environment where fungi grow is favorably damaged, the fungi on the scalp are less prone to propagation, and the anti-dandruff effect of the anti-dandruff composition is more lasting and long-acting.

In addition, the water-oil balance of the scalp is adjusted, the growth of scalp fungi is inhibited, and the scalp itching condition of the scalp is favorably reduced to a certain extent, so that the alopecia caused by scratching the scalp is favorably reduced, and the alopecia condition is favorably reduced to a certain extent.

Preferably, the anti-dandruff composition further comprises the following components in parts by mass:

0.5-0.9 part of cocoyl hydroxyethyl imidazoline;

0.1-0.4 part of hydroxypropyl distearyl dimethyl ammonium chloride.

By adopting the technical scheme, the cocoyl hydroxyethyl imidazoline and the hydroxypropyl distearyl dimethyl ammonium chloride are added for mutual synergistic compounding, so that the synergistic effect of the gentiana scabra bunge extract, the gentiana macrophylla extract and the swertia japonica extract can be better promoted, the water-oil balance of the scalp can be better adjusted, and meanwhile, the antibacterial and bactericidal effects of the anti-dandruff composition are better, so that the anti-dandruff effect of the anti-dandruff composition is longer-lasting and longer-acting, and the hair loss can be favorably reduced to a certain extent.

In a second aspect, the application provides a shampoo containing the anti-dandruff composition, and the following technical scheme is adopted:

a shampoo containing the anti-dandruff composition comprises the following components in percentage by mass:

10-15% of an anti-dandruff composition;

acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer 0.1-0.4%;

polyethylene glycol-12.01-0.04%;

1 to 1.5 percent of thickening agent;

1-2% of a foam booster;

0.7-1.1% of preservative;

0.6 to 1.0 percent of softener;

0.05 to 0.15 percent of chelating agent;

0.01 to 0.05 percent of pH regulator;

the balance being water.

By adding the composition into shampoo, the instant anti-dandruff effect of the shampoo is favorably improved, so that the residual dandruff after hair cleaning is less; meanwhile, the scalp is better nourished, so that the scalp is not easy to be dried and the cutin of the scalp is not easy to fall off due to over-cleaning; in addition, the water-oil balance of the scalp can be better adjusted, so that the scalp is not easy to breed fungi due to excessive oil of the scalp caused by excessive nourishing; the shampoo is also beneficial to better bacteriostasis and sterilization, so that the anti-dandruff effect of the shampoo is longer-lasting and long-acting, and the hair loss is also favorably reduced to a certain extent.

Preferably, the softener comprises one or more of guar hydroxypropyl trimethyl ammonium chloride, cyclopentadimethyl siloxane, amino-terminated dimethyl siloxane and behenyl trimethyl ammonium chloride.

By adopting one or more substances as the softener, the hair softener is beneficial to better softening the hair, so that the hair is less prone to frizziness, knotting and bifurcation caused by over-cleaning.

Preferably, the softener is prepared from guar hydroxypropyl trimethyl ammonium chloride, cyclopentadimethylsiloxane, amino-terminated polydimethylsiloxane and behenyl trimethyl ammonium chloride, wherein the ratio of 1 (0.7-1): (0.5-0.7): (0.5-0.7) in a mass ratio.

By adopting the synergistic compounding of the substances in a specific ratio, the scalp nourishing liquid is beneficial to better nourishing the scalp and better regulating and controlling the water-oil balance of the scalp, so that the scalp is less prone to being too greasy due to over-nourishing.

Preferably, the shampoo containing the anti-dandruff composition further comprises the following components in percentage by mass:

0.4 to 0.7 percent of essence.

By adding the essence, the fragrance of the shampoo is more pleasant, so that the shampoo is favorably welcomed by consumers, and the economic value of the shampoo is higher.

Preferably, the preservative comprises one or more of sodium salicylate, climbazole, sodium benzoate, and benzyl alcohol.

By adopting one or more substances as the preservative, the preservative effect of the shampoo is favorably improved, and simultaneously, the scalp is not easy to be stimulated, so that the scalp is favorably protected.

Preferably, the foam booster is cocamide MEA and sodium C12-14 olefin sulfonate.

The coconut oil amide MEA and the C12-14 olefin sodium sulfonate are compounded to serve as the foam enhancer, so that the shampoo can be better foamed in use, the use experience of the shampoo is better, the popularity of the shampoo to consumers is better improved, and the economic value of the shampoo is higher.

In a third aspect, the application provides a preparation method of a shampoo containing an anti-dandruff composition, and the following technical scheme is adopted:

a method for preparing shampoo containing anti-dandruff composition comprises the following steps:

step 1, taking 20% of the total mass of water, and dissolving acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer in the water to form a pre-dissolved substance for later use;

step 2, adding 30 percent of the total mass of water into a container, and adding the guar propyl trimethyl ammonium chloride into the container for dissolving;

step 3, continuously adding the cocamide MEA, the decyl glucoside, the hydroxypropyl distearyl dimethyl ammonium chloride, the hydrolyzed jojoba esters, the behenyl trimethyl ammonium chloride, the chelating agent and the pH regulator into a container, uniformly mixing, and raising the temperature to 83-87 ℃;

step 4, continuously adding the pre-dissolved substance obtained by dissolving in the step 1 into the container, and uniformly mixing;

step 5, mixing the thickening agent and the polyethylene glycol-12 to form a pre-mixture, adding the pre-mixture into a container, and uniformly mixing;

step 6, continuously adding ammonium laureth sulfate into the container, homogenizing until the ammonium laureth sulfate is completely dissolved, continuously adding the remaining water, uniformly mixing, and reducing the temperature in the container;

and 7, mixing cocoyl hydroxyethyl imidazoline and climbazole, heating until climbazole is completely dissolved to form a pre-dissolved mixture, adding the pre-dissolved mixture under the stirring condition when the temperature in the container is reduced to be below 50 ℃, then sequentially adding dimethiconol, C12-14 olefin sodium sulfonate, essence, gentiana scabra bunge extract, cyclopentadimethylsiloxane, sodium benzoate, benzyl alcohol, gentiana macrophylla extract, swertia japonica extract and amodimethicone, and uniformly mixing to obtain the shampoo containing the anti-dandruff composition.

The substances are added step by step, and the adding temperature of each substance is controlled, so that the components can better mutually cooperate and better play a role, the shampoo can achieve a better instant dandruff removing effect and a lasting and long-acting dandruff removing effect, and meanwhile, the shampoo is beneficial to better maintaining hair and adjusting the water-oil balance of the hair, so that the hair is not easy to have an excessively greasy condition, and the alopecia can be reduced to a certain extent.

In summary, the present application has the following beneficial effects:

1. the laureth sulfate ammonium, the decyl glucoside, the hydrolyzed jojoba esters, the dimethiconol, the gentian extract, the gentiana macrophylla extract and the swertia davidi extract in a specific proportion are adopted to be compounded in a synergistic manner, so that the instant anti-dandruff effect of the anti-dandruff composition is better improved, the scalp is better nourished, and physiological dandruff caused by dryness of the scalp is reduced; in addition, the composition is beneficial to better inhibiting the growth of the dandruff spore bacteria, so that pathological dandruff is reduced, and the anti-dandruff effect of the anti-dandruff composition is longer and longer lasting.

2. By adding the gentiana scabra bunge extract, the gentiana macrophylla extract and the swertia davidi extract, the water and oil of the scalp can be better regulated and controlled to be more balanced, so that the scalp is less prone to excessive oil production due to nourishing, the fungus breeding of the scalp can be better reduced, and the alopecia can be better reduced to a certain extent.

3. The coconut oil hydroxyethyl imidazoline and the hydroxypropyl distearyl dimethyl ammonium chloride are added for synergistic compounding, so that the compounding effect of the gentiana scabra bunge extract, the gentiana macrophylla extract and the swertia japonica thunb extract can be better promoted, and the long-lasting and long-acting anti-dandruff effect of the anti-dandruff composition can be better promoted.

4. By adding the composition into shampoo, the shampoo can achieve better instant dandruff removing effect, better nourishing effect, better long-lasting and long-acting dandruff removing effect and better alopecia reduction to a certain extent.

5. By controlling the adding sequence and the adding temperature of the components, the components can better cooperate and act, so that the prepared shampoo has better instant anti-dandruff effect, nourishing effect, long-lasting anti-dandruff effect and alopecia reduction effect.

Detailed Description

The present application will be described in further detail with reference to examples.

The source of the raw materials for the following examples and comparative examples are detailed in table 1.

TABLE 1

Example 1

The embodiment of the application discloses an anti-dandruff composition, which consists of the following components in parts by mass:

8kg of ammonium laureth sulfate; decyl glucoside 0.3kg; 0.1kg of jojoba esters is hydrolyzed; 0.7kg of dimethiconol; 0.2kg of gentian extract; 0.1kg of gentiana macrophylla extract; 0.1kg of swertia extract.

Example 2

12kg of ammonium laureth sulfate; decyl glucoside 0.7kg; 0.3kg of jojoba esters are hydrolyzed; 1.2kg of dimethiconol; 0.5kg of gentian extract; 0.3kg of gentiana macrophylla extract; 0.3kg of swertia extract.

Example 3

10kg of ammonium laureth sulfate; decyl glucoside 0.5kg; 0.2kg of jojoba esters are hydrolyzed; 1kg of dimethiconol; 0.3kg of gentian extract; 0.2kg of gentiana macrophylla extract; 0.2kg of swertia herb extract.

Example 4

The difference from example 3 is that:

the anti-dandruff composition also comprises the following components in parts by mass: 0.5kg of cocoyl hydroxyethyl imidazoline; 0.1kg of hydroxypropyl distearyl dimethyl ammonium chloride.

Example 5

The difference from example 3 is that:

the anti-dandruff composition also comprises the following components in parts by mass: 0.9kg of cocoyl hydroxyethyl imidazoline; 0.4kg of hydroxypropyl distearyl dimethyl ammonium chloride.

Example 6

The difference from example 3 is that:

the anti-dandruff composition also comprises the following components in parts by mass: 1.3kg of cocoyl hydroxyethyl imidazoline.

Example 7

The difference from example 3 is that:

the anti-dandruff composition also comprises the following components in parts by mass: 1.3kg of hydroxypropyl distearyl dimethyl ammonium chloride.

Comparative example 1

The application discloses an anti-dandruff composition, which consists of the following components in parts by mass:

10kg of ammonium laureth sulfate; decyl glucoside 0.5kg.

Comparative example 2

0.2kg of jojoba esters are hydrolyzed; 1kg of dimethiconol.

Comparative example 3

10kg of ammonium laureth sulfate; decyl glucoside 0.5kg; 0.2kg of jojoba esters are hydrolyzed; 1kg of dimethiconol.

Comparative example 4

The difference from example 3 is that: equal amount of gentiana extract is used to replace gentiana macrophylla extract.

Comparative example 5

The difference from example 3 is that: equal amount of gentiana macrophylla extract is used for replacing the swertia japonica extract.

Comparative example 6

The difference from example 3 is that: equal amount of swertia extract is used to replace radix Gentianae extract.

Experimental example 1

The application experimental example discloses a shampoo containing an anti-dandruff composition, which comprises the following components in parts by mass:

10kg of anti-dandruff composition; 0.1kg of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer; 0.01kg of polyethylene glycol-12; 1kg of thickening agent; 1kg of foam booster; 0.7kg of preservative; 0.6kg of softener; 0.05kg of chelating agent; 0.01kg of pH regulator; 86.53kg of water.

In this example, an antidandruff composition was prepared for example 1.

The thickening agent may be any thickening agent conventional in the art, and in this example, is specifically cocamide DEA.

Any foaming agent conventional in the art can be used as the foaming agent, and in this embodiment, cocamide MEA and sodium C12-14 olefin sulfonate are specifically used, and the mass ratio of the cocamide MEA to the sodium C12-14 olefin sulfonate is 8:7.

The preservative can be any preservative conventional in the field, in this embodiment, sodium salicylate, climbazole, sodium benzoate and benzyl alcohol are specifically selected, and the mass ratio of sodium salicylate, climbazole, sodium benzoate and benzyl alcohol is 3.

Any softener conventional in the field can be selected as the softener, in this embodiment, guar hydroxypropyl trimonium chloride and behenyl trimonium chloride are specifically selected, and the mass ratio of the guar hydroxypropyl trimonium chloride to the behenyl trimonium chloride is 2:1.

The chelating agent may be any chelating agent conventional in the art, and in this example, disodium EDTA is particularly preferred.

The pH adjuster may be any pH adjuster conventional in the art, and in this embodiment, citric acid is specifically selected.

The application also discloses a preparation method of the shampoo containing the anti-dandruff composition, which comprises the following steps:

step 1, cleaning production equipment such as an emulsifying pot and a stirring kettle required by production, taking 20% of the total mass of water, adding acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer into the water, and stirring until the acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer is completely dissolved to form a pre-dissolved substance for later use.

And 2, adding 30 percent of the total mass of the water into an emulsifying pot, adding the guar gum propyl trimethyl ammonium chloride into the emulsifying pot, and uniformly stirring.

And 3, continuously adding the cocamide MEA, the decyl glucoside, the hydroxypropyl distearyl dimethyl ammonium chloride, the hydrolyzed jojoba esters, the behenyl trimethyl ammonium chloride, the EDTA disodium and the citric acid into the emulsifying pot while stirring, uniformly stirring and mixing, and raising the temperature to 83 ℃.

And 4, continuously adding the pre-dissolved substance obtained by dissolving in the step 1 into an emulsifying pot while stirring, and uniformly stirring and mixing.

And 5, mixing the cocamide DEA and the polyethylene glycol-12, uniformly stirring to form a pre-mixture, adding the pre-mixture into an emulsifying pot, and continuously stirring the mixture in the emulsifying pot until the pre-mixture is uniformly mixed with the mixture in the emulsifying pot.

And 6, continuously adding ammonium laureth sulfate into the emulsifying pot, homogenizing until the ammonium laureth sulfate is completely dissolved, continuously adding the rest water, stirring and mixing uniformly, and cooling the emulsifying pot under natural conditions.

And 7, mixing cocoyl hydroxyethyl imidazoline and climbazole, heating until climbazole is completely dissolved to form a pre-dissolved mixture, adding the pre-dissolved mixture into an emulsifying pot under the stirring condition when the temperature in the emulsifying pot is reduced to be below 50 ℃, then sequentially adding dimethiconol, C12-14 olefin sodium sulfonate, a gentian extract, sodium benzoate, benzyl alcohol, a gentiana macrophylla extract and a swertia extract, and uniformly mixing to obtain the shampoo containing the anti-dandruff composition.

Experimental example 2

The difference from experimental example 1 is that: the addition quality of each component is different, and the specific quality is as follows:

15kg of anti-dandruff composition; 0.4kg of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer; polyethylene glycol-12.04kg; 1.5kg of thickening agent; 2kg of foam booster; 1.1kg of preservative; 1kg of softener; 0.15kg of chelating agent; 0.05kg of pH regulator; water 78.76kg.

Experimental example 3

12kg of anti-dandruff composition; 0.3kg of acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer; polyethylene glycol-12.02kg; 1.2kg of thickening agent; 1.5kg of foam booster; 1kg of preservative; 0.8kg of softener; 0.1kg of chelating agent; 0.03kg of pH regulator; 83.05kg of water.

Experimental example 4

The difference from experimental example 3 is that:

the shampoo containing the anti-dandruff composition also contains 0.4kg of component essence.

The softener is specifically selected from guar hydroxypropyl trimethyl ammonium chloride, cyclopentadimethylsiloxane, amino-terminated polydimethylsiloxane and behenyl trimethyl ammonium chloride, and the mass ratio of the guar hydroxypropyl trimethyl ammonium chloride to the cyclopentadimethylsiloxane to the amino-terminated polydimethylsiloxane to the behenyl trimethyl ammonium chloride is 1:0.7:0.5:0.5.

the perfume is added in step 7 after the addition of the sodium C12-14 olefin sulfonate and before the addition of the gentian extract; cyclopentadimethylsiloxane is added in step 7 after the addition of the gentian extract and before the sodium benzoate; the amino-terminated polydimethylsiloxane is added after the addition of the swertia extract in step 7.

Experimental example 5

The difference from experimental example 3 is that:

the shampoo containing the anti-dandruff composition also contains 0.7kg of essence.

The softener is specifically selected from guar hydroxypropyl trimethyl ammonium chloride, cyclopentadimethylsiloxane, amino-terminated polydimethylsiloxane and behenyl trimethyl ammonium chloride, and the mass ratio of the guar hydroxypropyl trimethyl ammonium chloride to the cyclopentadimethylsiloxane to the amino-terminated polydimethylsiloxane to the behenyl trimethyl ammonium chloride is 1:1:0.7:0.7.

the essence is added in step 7 after the addition of the sodium C12-14 olefin sulfonate and before the addition of the gentian extract; cyclopentadimethylsiloxane is added in step 7 after the addition of the gentian extract and before the sodium benzoate; the amino-terminated polydimethylsiloxane is added after the addition of the swertia extract in step 7.

Experimental example 6

The difference from experimental example 5 is that: the mass ratio of the guar hydroxypropyl trimethyl ammonium chloride, the cyclopentadimethyl siloxane, the amino-terminated dimethyl siloxane and the behenyl trimethyl ammonium chloride is 1:0.5:0.3:0.3.

experimental example 7

The difference from experimental example 5 is that: the mass ratio of the guar hydroxypropyl trimethyl ammonium chloride, the cyclopentadimethyl siloxane, the amino-terminated dimethyl siloxane and the behenyl trimethyl ammonium chloride is 1:1.5:1:1.

experimental example 8

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in example 2.

Experimental example 9

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in example 3.

Experimental example 10

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in example 4.

Experimental example 11

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in example 5.

Experimental example 12

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in example 6.

Experimental example 13

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in example 7.

Comparative Experimental example 1

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in comparative example 1.

Comparative experiment example 2

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in comparative example 2.

Comparative experiment example 3

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in comparative example 3.

Comparative experiment example 4

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in comparative example 4.

Comparative experiment example 5

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in comparative example 5.

Comparative experiment example 6

The difference from experimental example 3 is that: an anti-dandruff composition was prepared as in comparative example 6.

Experiment 1

Inoculating the spore bacteria of the dandruff in a nutrient broth culture medium to form a culture solution. And the nutrient broth culture medium is a nutrient broth culture medium purchased from Kyowa Kagaku microbial science Co., ltd., product number 022010.

Then, the number of spores of Pityrosporum ovale (CFU/mL) in the culture solution was measured by dilution plating, and then, the amount of the dandruff was measuredThe number of spore bacteria is 3.0 × 10 ⁶ CFU/mL。

Then, 13 parts of the above culture solution were taken, 10mL in each part, and 0.1mL of the antidandruff composition obtained in the above example or comparative example was added, respectively, and the spores of Pityrosporum ovale were aerobically cultured at 37 ℃ for 5 days, and finally the number of spores of Pityrosporum ovale (CFU/mL) in the culture solution after 2 days of culture was measured and recorded by dilution plating.

The data from the above experiments are detailed in table 2.

TABLE 2

	Number of Pityrosporum ovale after 2 days of culture (CFU/mL)
		Example 1	5.2×10 ³
Example 2	5.1×10 ³
		Example 3	5.0×10 ³
Example 4	3.3×10 ³
		Example 5	3.1×10 ³
Example 6	4.8×10 ³
		Example 7	4.7×10 ³
Comparative example 1	9.1×10 ⁷
		Comparative example 2	9.5×10 ⁷
Comparative example 3	9.3×10 ⁷
		Comparative example 4	8.2×10 ⁷
Comparative example 5	8.0×10 ⁷
		Comparative example 6	7.9×10 ⁷

According to the comparison of the data of example 3 and comparative examples 1-6 in Table 2, the ammonium laureth sulfate having an anti-dandruff effect and decyl glucoside added alone do not have the effect of inhibiting the growth of dandruff bacilli; hydrolyzed jojoba esters and dimethiconol with nourishing effect are added independently, so that the growth of the dandruff spore bacteria cannot be inhibited; meanwhile, substances with the anti-dandruff effect and the nourishing effect are added, and the effect of inhibiting the growth of the dandruff spore bacteria is avoided; any two extracts of the gentiana scabra bunge extract, the gentiana macrophylla bunge extract and the swertia davidii extract are added, so that the growth of the scurf spores is inhibited to a certain extent, but the inhibition effect is not as fast as the growth speed of the scurf spores, and the scurf spores still grow. Therefore, only by adopting the synergistic compounding of the gentiana scabra bunge extract, the gentiana macrophylla extract and the swertia davidi extract, the growth of the dandruff spore bacteria can be better inhibited, a better antibacterial and bactericidal effect is achieved, any substance is lacked, the bacteriostatic and bactericidal effect is easily greatly influenced, and further, the effects of water-oil balance, long-lasting and long-acting dandruff removal and alopecia reduction of the scalp are influenced.

According to the comparison of the data of the examples 3-7 in the table 2, the antibacterial and bactericidal effects of the anti-dandruff composition can be better promoted only by adding cocoyl hydroxyethyl imidazoline and hydroxypropyl distearyl dimethyl ammonium chloride to be compounded with each other, and any substance is lacked, so that the antibacterial and bactericidal effects of the anti-dandruff composition are easily greatly influenced.

Experiment 2

Randomly selecting 190 long-hair female volunteers with similar scurf problems, wherein the age is 25-45 years, randomly dividing the volunteers into 19 groups of 10 persons, respectively using commercially available shampoo commonly used at ordinary times for each group of volunteers, and observing and recording the scurf visible condition on hair after the hair is dried; then after washing the hair for 24 hours, washing the hair once again by using the common shampoo sold in the market at ordinary times, filtering the washed clean water by using a filter cloth bag, collecting the washed dandruff, drying, weighing and recording (mg); then, after collecting the dandruff for 48 hours, using the common shampoo sold in the market to wash the hair again, filtering the washed clean water by using a filter cloth bag, collecting the washed dandruff, drying, weighing and recording (mg); after the 2 nd dandruff collection is completed for 72 hours, the hair is washed once again by using the common shampoo sold in the market at ordinary times, the clean water washed off is filtered by using the filter cloth bag, the washed dandruff is collected, dried and weighed for recording (mg); after which the hair was re-rinsed at 72h intervals for one month and the amount of dandruff (mg) collected on day 15 and day 30 was recorded.

Then, each group of volunteers respectively uses the shampoo containing the anti-dandruff composition of the experimental example or the comparative experimental example, and observes and records the condition of visible dandruff on hair after the hair is dried; then, after the hair is washed for 24 hours, the hair is washed once again by using the shampoo containing the anti-dandruff composition corresponding to the experimental example or the comparative experimental example, the washed clean water is filtered by using a filter cloth bag, the washed dandruff is collected, dried and weighed and recorded (mg); then, after collecting dandruff for 48 hours, re-washing the hair once by using shampoo containing the dandruff removing composition corresponding to the experimental example or the comparative experimental example, filtering the washed clean water by using a filter cloth bag, collecting the washed dandruff, drying, and weighing and recording (mg); after 72 hours of the 2 nd dandruff collection, re-washing the hair once by using shampoo containing the dandruff removing composition of the corresponding experimental example or the comparative experimental example, filtering the washed clean water by using a filter cloth bag, collecting the washed dandruff, drying, and weighing and recording (mg); after which the hair was re-rinsed at 72h intervals for one month and the amount of dandruff (mg) collected on day 15 and on day 30 was recorded.

The data from the above experiments are detailed in table 3.

TABLE 3

Experiment 3

After the volunteers of experiment 2 used the shampoo containing the anti-dandruff composition for one month in the last continuous use, the greasiness of the hair was observed and recorded after 3 days of the shampoo used for the last time; and combing the hair from the top to the tail of the hair by using the comb with the same force, repeating the combing for 10 times, recording the smoothness degree of the comb in the hair combing process, and simultaneously recording the number (root) of the hair falling off in the hair combing process.

The data from the above experiments are detailed in table 4.

TABLE 4

According to the comparison of the data of the experimental example 3 and the comparative experimental examples 1-6 in the tables 3 and 4, the anti-dandruff composition in the comparative experimental example 1 only adds the substance with the anti-dandruff effect, the immediate anti-dandruff effect of the comparative experimental example 1 is excellent, but the problems of dry hair, knotting and even bifurcation are caused, the condition that the scalp is too dry due to over-cleaning is easy to occur, and the problem that the physiological dandruff is increased is easy to occur; the anti-dandruff composition in the comparative experiment example 2 is only added with substances with nourishing effects, the nourishing effect of the comparative experiment example 2 is excellent, but the anti-dandruff composition has poor anti-dandruff effect due to the fact that the substances with anti-dandruff effect do not exist, and the scalp is easy to oil easily due to scalp nourishing, so that the water-oil balance of the scalp is difficult to control, and further the greasiness of the scalp and the effect of reducing alopecia are easily influenced; the anti-dandruff composition in the comparative experiment example 3 is added with the substances with anti-dandruff effect and the substances with nourishing effect, and the comparative experiment example 3 realizes better instant anti-dandruff effect and better hair moisturizing effect at the same time, so that the hair is less prone to frizzy, knotted and even forked; any two extracts of the gentiana scabra bunge extract, the gentiana macrophylla bunge extract and the swertia davidii bunge extract are added in the comparative experiment examples 4-6, but the lasting long-acting anti-dandruff effect of the comparative experiment examples 4-6 is not obvious, which shows that only when the gentiana scabra bunge extract, the gentiana macrophylla bunge extract and the swertia davidi bunge extract are compounded with each other in a synergistic manner, the water-oil balance of the scalp can be better adjusted, the growth of dandruff spore bacteria of the scalp can be better inhibited, and the anti-dandruff effect is more lasting and long-acting.

In conclusion, the synergistic compounding of the substances is beneficial to improving the instant anti-dandruff effect of the shampoo and nourishing the scalp better, so that the scalp is not easy to generate physiological dandruff due to over-dry scalp caused by over-strong anti-dandruff cleaning power; meanwhile, the scalp can be better conditioned, so that the water and oil of the scalp are balanced, and the scalp is less prone to being too greasy and losing hair; in addition, the shampoo is beneficial to better inhibiting the growth of the dandruff spore bacteria, so that the pathological dandruff of the scalp is reduced, and the dandruff removing effect of the shampoo is longer and longer lasting.

According to the comparison of the data in the experimental examples 3-7 in the tables 2 and 3, the synergistic combination of the guar hydroxypropyl trimonium chloride, the cyclopentadecyl dimethyl siloxane, the amino-terminated dimethyl siloxane and the behenyl trimethyl ammonium chloride in a specific ratio is beneficial to better reducing the influence of the softener on the water-oil balance of the scalp, so that the scalp is less prone to being too greasy due to excessive nourishing and alopecia.

According to the comparison of the data of the experimental example 3 and the experimental examples 8-14 in the tables 2 and 3, the synergistic combination of the gentiana scabra bunge extract, the gentiana macrophylla extract and the swertia japonica extract can be better promoted by adding the cocoyl hydroxyethyl imidazoline and the hydroxypropyl distearyl dimethyl ammonium chloride compounded in a specific ratio, so that the effects of bacteriostasis and sterilization of the shampoo and regulation of the water-oil balance of the scalp are better, and the effect of lasting and long-acting anti-dandruff of the shampoo is better.

The above embodiments are preferred embodiments of the present application, and the protection scope of the present application is not limited by the above embodiments, so: all equivalent changes made according to the structure, shape and principle of the present application shall be covered by the protection scope of the present application.

Claims

1. An anti-dandruff composition characterized by: the composition comprises the following components in parts by mass:

8-12 parts of ammonium laureth sulfate;

decyl glucoside 0.3-0.7 parts;

0.1-0.3 part of hydrolyzed jojoba esters;

0.7-1.2 parts of dimethiconol;

0.2-0.5 parts of gentian extract;

0.1-0.3 parts of gentiana macrophylla extract;

0.1-0.3 part of swertia extract.

2. An anti-dandruff composition characterized by: the composition comprises the following components in parts by mass:

8-12 parts of ammonium laureth sulfate;

decyl glucoside 0.3-0.7 parts;

0.1-0.3 part of hydrolyzed jojoba esters;

0.7-1.2 parts of dimethiconol;

0.2-0.5 parts of gentian extract;

0.1-0.3 parts of gentiana macrophylla extract;

0.1-0.3 part of swertia extract;

0.5-0.9 part of cocoyl hydroxyethyl imidazoline;

0.1-0.4 part of hydroxypropyl distearyl dimethyl ammonium chloride.

3. A shampoo containing an anti-dandruff composition according to any of claims 1 to 2, characterized in that: the composite material comprises the following components in percentage by mass:

10-15% of an anti-dandruff composition;

acrylic acid (ester)/C10-30 alkanol acrylate crosslinked polymer 0.1-0.4%;

polyethylene glycol-12.01-0.04%;

1 to 1.5 percent of thickening agent;

1-2% of a foam booster;

0.7-1.1% of preservative;

0.6 to 1.0 percent of softener;

0.05 to 0.15 percent of chelating agent;

0.01 to 0.05 percent of pH regulator;

the balance being water.

4. A shampoo containing an anti-dandruff composition according to claim 3, wherein: the softener comprises one or more of guar hydroxypropyl trimethyl ammonium chloride, cyclopentadimethylsiloxane, amino-terminated polydimethylsiloxane and behenyl trimethyl ammonium chloride.

5. Shampoo containing an anti-dandruff composition according to claim 4, characterized in that: the softener is prepared from guar hydroxypropyl trimethyl ammonium chloride, cyclopentadidimethyl siloxane, amino-terminated dimethyl siloxane and behenyl trimethyl ammonium chloride, wherein the ratio of 1 (0.7-1) to the total weight of the softener is as follows: (0.5-0.7): (0.5-0.7) in a mass ratio.

6. Shampoo containing an anti-dandruff composition according to any one of claims 3 to 5, characterized in that: the shampoo containing the anti-dandruff composition also comprises the following components in percentage by mass:

0.4 to 0.7 percent of essence.

7. Shampoo containing an anti-dandruff composition according to any one of claims 3 to 5, characterized in that: the preservative is selected from sodium salicylate, climbazole, sodium benzoate and benzyl alcohol, and the mass ratio of the sodium salicylate to the climbazole to the sodium benzoate to the benzyl alcohol is 3.

8. Shampoo containing an anti-dandruff composition according to any one of claims 3 to 5, characterized in that: the foam booster is cocamide MEA and C12-14 olefin sodium sulfonate.

9. A method for preparing a shampoo containing an anti-dandruff composition according to claim 6, wherein: the method comprises the following steps:

step 2, taking 30% of the total mass of water into a container, and adding guar hydroxypropyl trimethyl ammonium chloride into the container for dissolving;