CN113768846A - Nourishing anti-dandruff shampoo and preparation method thereof - Google Patents

Nourishing anti-dandruff shampoo and preparation method thereof Download PDF

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CN113768846A
CN113768846A CN202111249560.7A CN202111249560A CN113768846A CN 113768846 A CN113768846 A CN 113768846A CN 202111249560 A CN202111249560 A CN 202111249560A CN 113768846 A CN113768846 A CN 113768846A
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water
mixture
nourishing
shampoo
agent
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CN113768846B (en
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简经红
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Hunan Benmei Bio Tech Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention provides a nourishing anti-dandruff shampoo, and relates to the technical field of cosmetics. The shampoo comprises the following components in percentage by weight: 18-22% of conditioning agent, 15-28% of surfactant, 2.0-2.5% of antistatic agent, 0.8-1.2% of thickening agent, 0.10-0.15% of pH regulator, 0.4-0.7% of preservative, 0.05-0.12% of chelating agent, 1-2% of essence, 0.5-2% of softener and the balance of water. The components are added with the camellia extract, so that the shampoo has the advantages of nourishing hair follicles, enabling hairs to be smooth, enhancing hair toughness, preventing hair loss and the like while maintaining the scalp, and the obtained shampoo can be used for cleaning and protecting the scalp, enabling the hairs to be smooth and lasting fragrance by controlling the proportion of the components.

Description

Nourishing anti-dandruff shampoo and preparation method thereof
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to a nourishing anti-dandruff shampoo and a preparation method thereof.
Background
Researches find that the shampoo for improving scalp problems such as scurf, greasy head and itchy head cannot meet consumer appeal, in the current shampoo market, besides the traditional hair flexibility effect, the shampoo capable of relieving the load of the scalp and nursing the scalp is a new pursuit direction of consumers, but the product on the market has relatively single function: the soft shampoo generally generates scurf, the anti-dandruff shampoo generally generates hair loss, and the anti-hair loss shampoo also generates rough hair, so that all in all, various requirements of consumers cannot be met.
In addition, most of the anti-dandruff antipruritic agents adopted by anti-dandruff products in domestic and foreign markets are chemical synthetic substances such as Zinc Pyrithione (ZPT), piroctone olamine salt (OCT) and the like, and the substances have many defects such as certain sensitization, irritation and instability and are easy to relapse after being stopped. Through years of research and research, the applicant finds that all hair problems are caused by the fact that scalp is not well maintained, and in order to maintain the scalp well, firstly, plant type and biological type components are preferably selected from component selection materials, and in addition, the surfactant must not irritate the scalp.
Meanwhile, the scalp care is met, the experience of consumers needs to be improved, and if the scalp care product is rich in foam, easy to wash, lasting in fragrance and fresh and pleasant in fragrance, the important research points of the shampoo industry are provided, but according to the survey, most of the products on the market which declare that the plant dandruff removing agent is mainly a chemical dandruff removing agent and is combined with a small amount of plant dandruff removing components, the products really exert the effective dandruff removing and itching relieving effects by using natural plant extracts are very few, and the products which really realize the scalp conditioning effects of dandruff removing and itching in the market at present are very few.
The oil tea is a unique oil tree species in China, the whole body of the oil tea is precious, and the oil tea prepared by processing the tea seeds is high-quality edible oil, has good color, fragrant taste and rich nutrition, and has the effects of reducing blood pressure and blood fat, softening blood vessels and the like. Tea bran, also called tea seed cake, is purple brown granule, is residue left after oil extraction from wild camellia oil fruit, tea saponin obtained by extracting tea bran through scientific process belongs to triterpenoid, which is an excellent nonionic natural surfactant and has the effects of washing hair, protecting hair, blackening hair, removing dandruff, preventing alopecia and the like.
For example, Chinese patent application 202011111946.7 discloses a formula of a smoothing and anti-dandruff tea bran shampoo and a preparation process thereof, which relate to the technical field of cleaning products and comprise the following raw materials in parts by weight: 5-10 parts of tea seed powder, 6-10 parts of sodium lauroyl sarcosinate, 5-8 parts of sodium cocoyl isethionate, 5-8 parts of sodium methyl lauroyl taurate, 5-8 parts of decyl glucoside, 0.2-1 part of polyquaternary ammonium salt, 1.5-3 parts of cocamide DEA, 0.1 part of EDTA-2Na, 0.1-0.3 part of allantoin, 10-15 parts of cocamidopropyl betaine, 1-2 parts of polygonum multiflorum extract, 1-3 parts of burley leaf extract, 1-2 parts of liquorice extract, 0.2-1 part of angelica sinensis extract, 0.2-1 part of ginseng extract, 0.2-1 part of camellia extract, 0.3-0.6 part of phenoxyethanol, 0.3-0.6 part of benzoic acid, 0.02-0.2 part of citric acid, 0.1-0.5 part of tea oil and the balance of water to 100 parts. The application adds a preservative to the shampoo components, is easy to cause uncomfortable reactions, and does not pay attention to the anti-dandruff effect of the shampoo.
Further, as disclosed in chinese patent application 201910523588.1, a dandruff-removing and itching-relieving scalp conditioning solution, a preparation method and an application thereof are disclosed, wherein the dandruff-removing and itching-relieving scalp conditioning solution comprises chamomile essential oil, camellia extract, juniper berry extract and kunzea leaf extract. The anti-dandruff itching-relieving scalp conditioning solution disclosed by the invention adopts four plant extracts, so that four effects of anti-dandruff itching relieving, bacteriostasis, sterilization, moisture retention and antioxidation are effectively exerted, and meanwhile, the four plant extracts are mutually synergistic to realize timely and effective scalp anti-dandruff itching-relieving conditioning effect.
Therefore, the tea bran shampoo capable of nourishing hair follicles and effectively removing dandruff and the preparation method thereof are needed.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide the nourishing anti-dandruff shampoo and the preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the nourishing anti-dandruff shampoo comprises the following components in percentage by weight: 18-22% of conditioning agent, 15-28% of surfactant, 2.0-2.5% of antistatic agent, 0.8-1.2% of thickening agent, 0.10-0.15% of pH regulator, 0.4-0.7% of preservative, 0.05-0.12% of chelating agent, 1-2% of essence, 0.5-2% of softener and the balance of water.
Preferably, the nourishing anti-dandruff shampoo comprises the following components in percentage by weight: 19-21% of conditioner, 18-27% of surfactant, 2.2-2.5% of antistatic agent, 1-1.1% of thickening agent, 0.12-0.15% of pH regulator, 0.5-0.6% of preservative, 0.08-0.10% of chelating agent, 1-2% of essence, 1-2% of softener and the balance of water.
Preferably, the nourishing anti-dandruff shampoo comprises the following components in percentage by weight: 19.2% of conditioner, 20% of surfactant, 2.5% of antistatic agent, 1.05% of thickening agent, 0.15% of pH regulator, 0.6% of preservative, 0.1% of chelating agent, 1% of essence, 2% of softener and 53.4% of water.
Wherein the conditioning agent is selected from the group consisting of polyethylene glycol-14M, butylated hydroxytoluene, and silica complex, camellia extract, a mixture of di (hydrogenated tallow) phthalic acid amide and water, ethylene glycol distearate, ethylene glycol stearate, a mixture of ethylene glycol and water, lauramidopropyl betaine, a mixture of sodium chloride and water, cocamidopropyl betaine, polydimethylsiloxane, dimethiconol, amodimethicone, sodium chloride, TEA dodecylbenzenesulfonate, C12-14 sec-alkanoleth-9, diamino PEG/PPG-41/3 aminoethyl PG-propyl dimethicone, dipropylene glycol, laureth-5, laureth-23, PEG-55 stearate, trideceth-12, glyceryl polyether, Laureth-4, phenoxyethanol, caprylyl glycol, methyl chloro isothiazolinone, the mixture of methyl isothiazolinone, magnesium chloride and magnesium nitrate, and one or more of polyquaternium-10.
The camellia extract comprises a camellia extract A and a camellia extract B;
the CAMELLIA extract A is a mixture of CAMELLIA (Camellia JAPONICA) flower extract, decyl glucoside, sodium PCA, water and a mixture of methylchloroisothiazolinone, methylisothiazolinone, magnesium chloride and magnesium nitrate;
the flos Camelliae Japonicae extractive solution B is a mixture of flos Camelliae Japonicae (Camellia JAPONICA) extract, propylene glycol, hexylene glycol, phenoxyethanol, ethylhexylglycerin and water.
In some preferred embodiments, the mass ratio of the camellia extract A to the camellia extract B is 0.05-2: 10; preferably 2: 10.
In the implementation process, the two camellia extracts with different compositions are added into the components, the known camellia extracts in the field have good antibacterial effect, and the implementation process of the invention unexpectedly discovers that the maintenance effect of the shampoo can be improved by mixing the two camellia extracts provided by the invention, the water-oil balance of the scalp can be effectively adjusted, the scalp is activated, the scalp is helped to recover normal metabolism, and a protective barrier is formed.
The surfactant is selected from one or more of sodium laureth sulfate, PPG-25-laureth-25, a mixture of sodium sulfate and water, a mixture of sodium lauroamphoacetate, sodium chloride and water, cocamide MEA, a mixture of cocoglycerides, glycerol and cocamide DEA;
the antistatic agent is selected from one or more of coconut acyl sodium isethionate, hydrogenated coconut oil, a mixture of sodium isethionate and water, and a mixture of behenyl trimethyl ammonium chloride, isopropyl alcohol and water;
preferably, the antistatic agent is a mixture of sodium cocoyl isethionate, hydrogenated coconut oil, sodium isethionate and water and a mixture of behenyl trimethyl ammonium chloride, isopropyl alcohol and water in a mass ratio of 1:1.
The thickening agent is selected from one or more of a mixture of guar hydroxypropyl trimethyl ammonium chloride, sodium chloride and water, and a mixture of acrylic acid (ester) copolymer and water.
The pH regulator is citric acid.
The preservative is selected from a mixture of methylparaben and/or DMDM hydantoin, formaldehyde and water.
The chelating agent is disodium EDTA.
The softener is polyquaternium-1.
The essence is conventional in the field.
The solvent is water.
In the implementation process, the invention unexpectedly discovers that the mass ratio of the conditioner to the surfactant in the shampoo components influences the performance of the shampoo to a certain extent, and the conditioner and the surfactant can be controlled to improve the absorption of the hair on the active ingredients in the shampoo, so that the effects of nourishing hair follicles and enhancing hair toughness are achieved
In some preferred embodiments, the mass ratio of the conditioning agent to the surfactant is 1:0.8-1.5, preferably the mass ratio of the conditioning agent to the surfactant is 1:1.0-1.2, further preferably the mass ratio of the conditioning agent to the surfactant is 1: 1-1.05.
The invention also provides a preparation method of the nourishing anti-dandruff shampoo, which comprises the following steps:
(1) adding the conditioner and water with the formula dosage into a stirring pot, soaking for 30 minutes, adding the surfactant and the antistatic agent, slowly stirring, heating to 85 ℃, keeping the temperature, stirring for 30 minutes, adding the thickening agent, the pH conditioner, the preservative and the chelating agent, continuing to keep the temperature, stirring for 30 minutes, and cooling after the components are uniformly dissolved;
(2) when the temperature is reduced to 45 ℃, adding essence and a softener, uniformly stirring, and continuously reducing to room temperature to obtain the nourishing anti-dandruff shampoo.
Compared with the prior art, the invention has the beneficial effects that:
(1) the components in the shampoo provided by the invention can obviously improve the interaction among the components by adjusting the types of the components, and the components are added with the camellia extract, so that the shampoo has the advantages of nourishing hair follicles, enabling hairs to be smooth, enhancing the toughness of hair strands, preventing hair loss and the like while maintaining the scalp;
(2) according to the invention, two camellia extracts are added into the shampoo, and the two camellia extracts are mixed for use, so that the maintenance effect of the shampoo can be improved, the water-oil balance of the scalp can be effectively adjusted, the scalp is activated, the scalp is helped to recover normal metabolism, and a protective barrier is formed;
(3) the quality ratio of the conditioner to the surfactant in the components of the shampoo can influence the performance of the shampoo to a certain extent, and the conditioner and the surfactant can be controlled to improve the absorption of the hair on effective components in the shampoo, so that the effects of nourishing hair follicles, enhancing hair toughness and improving long-term bacteriostasis are achieved.
Detailed Description
The features mentioned above in the description, or the features mentioned in the embodiments, may be combined arbitrarily. All the features disclosed in this specification may be combined in any suitable manner and each feature disclosed in this specification may be replaced by an alternative feature serving the same, equivalent or similar purpose. Thus, unless expressly stated otherwise, the features disclosed are merely generic examples of equivalent or similar features.
The invention will be further illustrated with reference to the following specific examples. These examples are intended to illustrate the invention and are not intended to limit the scope of the invention. The following examples are conducted under conditions specified, usually according to conventional conditions or according to conditions recommended by the manufacturer. All percentages and fractions are by weight unless otherwise specified.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. In addition, any methods and materials similar or equivalent to those described herein can be used in the methods of the present invention. The preferred embodiments and materials described herein are exemplary only.
The formulation of polyethylene glycol-14M, butylated hydroxytoluene and silica used in the following examples was purchased from Dow chemical (Shanghai) Inc. under the trade designation WSR-205; the camellia extract A is purchased from Jinchang biotechnology limited, Hunan, and has the commercial model of SC 01; the camellia extract B is purchased from Jinchang biotechnology limited, Hunan, and has the commercial model of SC 02; the mixture of di (hydrogenated tallow) phthalic acid amide and water was purchased from new materials, inc, hua nan, and is commercially available as TAB-2; the mixture of ethylene glycol distearate, ethylene glycol stearate, ethylene glycol and water was purchased from Guangzhou Star science and technology GmbH with a commercial model number of EGDS; a mixture of lauramidopropyl beet, sodium chloride and water was purchased from Shanghai King Chemicals, Inc. under a 20AB commercial model; cocamidopropyl betaine, dimethicone, dimethiconol, amodimethicone, sodium chloride, dodecylbenzene sulfonate TEA salt, C12-14 sec-alkanoleth-9, bisaminoPEG/PPG-41/3 aminoethyl PG-propyldimethicone, dipropylene glycol, laureth-5, laureth-23, PEG-55 stearate, trideceth-12, glycerin, laureth-4, phenoxyethanol, octylglycol and methylchloroisothiazolinone, and a mixture of methylisothiazolinone with magnesium chloride and magnesium nitrate were purchased from Cinchaku Biotech, Inc. of Hunan, and commercially available as emulsified silicone oil ES 65A; polyquaternium-10 is available from Dow chemical (Shanghai) Co., Ltd under the trade designation JR 400; the mixture of sodium laureth sulfate, PPG-25-laureth-25, sodium sulfate and water is available from Ostwald Korea, Guangdong, Chen, Onwei industries, Inc., and has a commercial model of AES (BASF/KAO); the mixture of sodium lauroamphoacetate, sodium chloride and water was purchased from Guangzhou Star science and technology GmbH with a commercial model of AMC; cocoamide MEA is purchased from Guangzhou Star science and technology Co., Ltd, and the commodity model is CMEA; a mixture of cocoglycerides, glycerin and cocamide DEA was purchased from wo odand odor studies pteltd, model 6501; the mixture of cocoyl sodium isethionate, hydrogenated coconut oil, sodium isethionate and water is purchased from Huanggang Yongan daily chemical Co Ltd, and the product model is ISELUX; the mixture of behenyl trimethyl ammonium chloride, isopropyl alcohol and water was purchased from clariant chemical (china) ltd and has a commercial model number of BT 85; a mixture of guar hydroxypropyltrimonium chloride, sodium chloride and water was purchased from Miwon Commercial co., Ltd, and is available under the Commercial model number guar C-14S; the mixture of acrylic acid (ester) copolymer and water has a commercial model of SF-1; methylparaben was purchased from clariant chemical (china) ltd; a mixture of DMDM hydantoin, formaldehyde, and water was purchased from Lonza Inc, with a commercial model of DMDMH; disodium EDTA was purchased from aksunobel chemicals (ningbo) ltd; the product model of polyquaternium-1 is C802; fragrances are available under the tradenames 5004489, 5004490 and 5004491.
Example 1 nourishing type anti-dandruff shampoo and preparation method thereof
The paint comprises the following components in percentage by weight:
Figure BDA0003322172570000061
Figure BDA0003322172570000071
the preparation method comprises the following steps:
(1) cleaning and sterilizing production equipment
(2) Accurately weighing water, WSR-205, JR400, camellia extract A, camellia extract B, EGDS, 20AB and ES65A, putting into a stirring pot, soaking for 30 minutes, adding AES, AEC, CMEA, 6501, ISELUX and BT85, stirring at a low speed and heating to 85 ℃, stirring at a high temperature for 30 minutes, adding C-14S, SF-1, citric acid, hydroxymethyl, DMDMH and EDTA disodium, stirring at a high temperature and stirring at a low speed for 30 minutes, cooling after the components are dissolved uniformly, (note that if the components are not completely dissolved, stirring at a low speed and keeping the temperature until the components are completely dissolved)
(3) Cooling to 45 deg.C, adding essence 5004489, 5004490, 5004491 and C802, stirring, comparing with standard sample, cooling to room temperature, and discharging.
Example 2 nourishing type anti-dandruff shampoo and preparation method thereof
The paint comprises the following components in percentage by weight:
Figure BDA0003322172570000072
Figure BDA0003322172570000081
the preparation method comprises the following steps:
(1) cleaning and sterilizing production equipment
(2) Accurately weighing water, WSR-205, JR400, camellia extract A, camellia extract B, EGDS, 20AB and ES65A, putting into a stirring pot, soaking for 30 minutes, adding AES, AEC, CMEA, 6501, ISELUX and BT85, stirring at a low speed and heating to 85 ℃, stirring at a high temperature for 30 minutes, adding C-14S, SF-1, citric acid, hydroxymethyl, DMDMH and EDTA disodium, stirring at a high temperature and stirring at a low speed for 30 minutes, cooling after the components are dissolved uniformly, (note that if the components are not completely dissolved, stirring at a low speed and keeping the temperature until the components are completely dissolved)
(3) Cooling to 45 deg.C, adding essence 5004489, 5004490, 5004491 and C802, stirring, comparing with standard sample, cooling to room temperature, and discharging.
Example 3 nourishing type anti-dandruff shampoo and preparation method thereof
The paint comprises the following components in percentage by weight:
Figure BDA0003322172570000082
Figure BDA0003322172570000091
the preparation method comprises the following steps:
(1) cleaning and sterilizing production equipment
(2) Accurately weighing water, WSR-205, JR400, camellia extract A, camellia extract B, EGDS, 20AB and ES65A, putting into a stirring pot, soaking for 30 minutes, adding AES, AEC, CMEA, 6501, ISELUX and BT85, stirring at a low speed and heating to 85 ℃, stirring at a high temperature for 30 minutes, adding C-14S, SF-1, citric acid, hydroxymethyl, DMDMH and EDTA disodium, stirring at a high temperature and stirring at a low speed for 30 minutes, cooling after the components are dissolved uniformly, (note that if the components are not completely dissolved, stirring at a low speed and keeping the temperature until the components are completely dissolved)
(3) Cooling to 45 deg.C, adding essence 5004489, 5004490, 5004491 and C802, stirring, comparing with standard sample, cooling to room temperature, and discharging.
Comparative example 1
The difference from example 3 is that only one camellia extract a is added to the composition, and camellia extract B is not added, and other steps and methods are the same as example 3.
Comparative example 2
The difference from example 3 is that only one camellia extract B is added to the composition, camellia extract a is not added, and other steps and methods are the same as example 3.
Comparative example 3
The difference from the example 3 is that the mass ratio of the camellia extract A to the camellia extract B in the components is 3:1, and other steps and methods are the same as the example 3.
Comparative example 4
The difference from example 3 is that: the mass ratio of the conditioning agent to the surfactant was 1:0.5, and the other steps and methods were the same as in example 3.
Namely:
Figure BDA0003322172570000101
comparative example 5
The difference from example 3 is that: the mass ratio of conditioning agent to surfactant was 1:1.5 and the other steps and methods were the same as in example 3.
Namely:
Figure BDA0003322172570000102
Figure BDA0003322172570000111
comparative example 6
A shampoo disclosed in prior art CN 110141541A.
Effect verification:
the detection methods described in the present invention are all detection methods disclosed in the prior art, and the applicant verifies the performance of the shampoo described in the present invention according to the related experimental methods.
1. Verification of antidandruff Effect-detection experiment for Pityrosporum ovale (Malassezia)
The test method comprises the following steps: plate contact method
The operation method comprises the following steps: removing hair and fat on pigskin, cutting into 4cm × 4cm square pieces, and sterilizing with Co 60-gamma ray irradiation.
Weighing Leeming-Notman culture medium base 44.0g in 1L deionized water, boiling to dissolve completely, adding 1.6mL olive oil per 80mL, autoclaving, cooling to about 50 deg.C, adding 40mg cycloheximide solution per 80mL under aseptic operation, and preparing LN plate (90mm × 15mm) for use. 100. mu.L of 1X 10 beads were each added dropwise to LN plates5-3×105And (3) uniformly coating the Marasmius bacterial suspension of CFU/mL for later use.
After uniformly wiping the surface of the pigskin with 0.5g of the shampoo sample prepared in application examples 1 to 3 and comparative examples 1 to 6 for 1min, rinsing the liquid soap on the pigskin with 100mL of sterile water for 1min for 2 times; after rinsing, the pigskin is placed in a biological safety cabinet to be aired in a ventilating mode until no obvious water drops exist on the surface of the pigskin, then the pigskin is attached to a bacteria-contaminated flat plate, the attaching time is 15min, the pigskin is removed after the attaching is finished, the flat plate is placed in a constant temperature box of (32 +/-2) DEG C to be cultured for 48 hours, the growth condition of malassezia is observed, the bacteriostasis rate is calculated (one decimal point is reserved in the calculation result), and the specific detection result is shown in the following table 1.
TABLE 1
Figure BDA0003322172570000112
Figure BDA0003322172570000121
According to the detection data in the table 1, the shampoo prepared in the embodiment 1-3 of the invention has obvious bacteriostatic effect, wherein the shampoo prepared in the embodiment 3 has the best bacteriostatic effect, can better adjust the micro-ecology of hair, the bacteriostatic rate of malassezia after 48 hours can still reach more than 90%, the bacteriostatic effect of the shampoo can be obviously influenced by changing the type or the mass ratio of the camellia extract in the comparative examples 1-3, and the durability of the bacteriostatic effect of the shampoo can be obviously influenced by changing the mass ratio of the surfactant to the conditioner in the comparative examples 4-5, so that the long-term bacteriostatic effect is influenced.
2. Hair follicle nourishing Performance test-Hair follicle improving Effect test
(1) Experimental animals: hair belongs to resting Kunming rats.
(2) Mouse hair loss model: the rats were subjected to a depilation treatment, and the growth period of hair was confirmed to be in the telogen phase.
(3) Grouping and administration: after 24 hours after depilation, 25 rats with smooth and skin-free depilated areas were selected, randomly divided into 5 groups of 5, and washed with the shampoo products prepared in application examples 1-5, respectively, at an area of 2cm × 3cm, once for 2 days, for 10 days. The blank groups were washed with clear water, and on day 10, skin tissue blocks were taken from the same positions on the backs of the mice in each group, fixed with 10% formalin, paraffin-embedded, sliced to a thickness of about 4-5 μm, stained by HE, and observed under light. Hair follicle counts, the number of follicles in 3 high power fields (. times.400) per case, were averaged and statistically processed as shown in Table 2.
TABLE 2
Examples of the invention Number of follicles (number/high power field)
Blank group 12.85±1.04
Example 1 18.48±1.10*
Example 2 18.76±1.13*
Example 3 20.56±0.95**
Comparative example 1 15.21±1.14
Comparative example 2 15.82±0.98
Comparative example 3 17.05±1.17
Comparative example 4 17.68±0.86*
Comparative example 5 17.89±0.94*
Comparative example 6 14.08±0.96
Note: p < 0.05, with significant differences compared to the blank control group; p < 0.001, with a very significant difference compared to the blank control group.
According to the detection data in the table 2, when the variety or the mass ratio of the camellia extract is not within the protection range of the invention, the hair follicle growth promoting effect of the prepared shampoo is obviously reduced, so that the camellia extract can obviously influence the hair growth promoting effect of the shampoo and can obviously influence the hair follicle growth promoting effect. The mass ratio of the surfactant to the conditioner affects the absorption of the effective components in the shampoo by the hair to a certain extent, and therefore affects the hair follicle growth promoting effect.
3. Shampoo performance test
The test method comprises the following steps: the shampoos prepared in examples 1-3 and comparative examples 4-6 were experienced by a group of 10 persons randomly searching for 60 volunteers, and were used every three days, and after 2 uses, the shampoo was scored at 10 points in the highest score and 0 point in the lowest score, and the scores of the respective volunteers were averaged (1 position after the decimal point was retained) and recorded in table 3, respectively.
TABLE 3
Wet combing property Dry combing property Antipruritic effect Anti-dandruff effect
Example 1 8.5 8.2 8.6 8.5
Example 2 8.6 8.4 8.4 8.6
Example 3 9.5 9.2 9.0 9.2
Comparative example 4 8.2 8.0 8.0 8.1
Comparative example 5 8.0 8.1 8.2 8.2
Comparative example 6 7.5 7.3 7.8 7.5
As can be seen from the detection data in the table 3, the washing water prepared by the invention has good dry/wet combing property, and good itching relieving effect and dandruff removing effect. Especially, the shampoo prepared in the embodiment 3 has better user experience and best comprehensive effect.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims (10)

1. A nourishing anti-dandruff shampoo is characterized in that: the paint comprises the following components in percentage by weight: 18-22% of conditioning agent, 15-28% of surfactant, 2.0-2.5% of antistatic agent, 0.8-1.2% of thickening agent, 0.10-0.15% of pH regulator, 0.4-0.7% of preservative, 0.05-0.12% of chelating agent, 1-2% of essence, 0.5-2% of softener and the balance of water.
2. The nourishing and anti-dandruff shampoo as claimed in claim 1, wherein: the paint comprises the following components in percentage by weight: 19-21% of conditioner, 18-27% of surfactant, 2.2-2.5% of antistatic agent, 1-1.1% of thickening agent, 0.12-0.15% of pH regulator, 0.5-0.6% of preservative, 0.08-0.10% of chelating agent, 1-2% of essence, 1-2% of softener and the balance of water.
3. The nourishing and anti-dandruff shampoo as claimed in claim 2, characterized in that: the paint comprises the following components in percentage by weight: 19.2% of conditioner, 20% of surfactant, 2.5% of antistatic agent, 1.05% of thickening agent, 0.15% of pH regulator, 0.6% of preservative, 0.1% of chelating agent, 1% of essence, 2% of softener and 53.4% of water.
4. The nourishing and anti-dandruff shampoo as claimed in claim 3, characterized in that: the conditioning agent is selected from the group consisting of polyethylene glycol-14M, butylated hydroxytoluene, and silica complex, camellia extract, a mixture of di (hydrogenated tallow) phthalic acid amide and water, ethylene glycol distearate, ethylene glycol stearate, a mixture of ethylene glycol and water, lauramidopropyl betaine, a mixture of sodium chloride and water, cocamidopropyl betaine, polydimethylsiloxane, dimethiconol, amodimethicone, sodium chloride, TEA dodecylbenzenesulfonate, C12-14 sec-alkanoleth-9, diamino PEG/PPG-41/3 aminoethyl PG-propyl dimethicone, dipropylene glycol, laureth-5, laureth-23, PEG-55 stearate, trideceth-12, glycerol, laureth-4, laureth-12, and mixtures thereof, Phenoxyethanol, octyl glycol, methyl chloro isothiazolinone, the mixture of methyl isothiazolinone, magnesium chloride and magnesium nitrate, and one or more of polyquaternium-10.
5. The nourishing and anti-dandruff shampoo as claimed in claim 4, wherein: the camellia extract is a mixture of a camellia extract A and a camellia extract B.
6. The nourishing and anti-dandruff shampoo as claimed in claim 5, wherein: the mass ratio of the camellia extract A to the camellia extract B is 0.05-2: 10.
7. The nourishing and anti-dandruff shampoo as claimed in claim 3, characterized in that: the surfactant is selected from one or more of sodium laureth sulfate, PPG-25-laureth-25, a mixture of sodium sulfate and water, a mixture of sodium lauroamphoacetate, sodium chloride and water, cocamide MEA, a mixture of cocoglycerides, glycerol and cocamide DEA;
the antistatic agent is selected from one or more of coconut acyl sodium isethionate, hydrogenated coconut oil, a mixture of sodium isethionate and water, and a mixture of behenyl trimethyl ammonium chloride, isopropyl alcohol and water;
the thickening agent is selected from one or more of a mixture of guar hydroxypropyl trimethyl ammonium chloride, sodium chloride and water, and a mixture of acrylic acid (ester) copolymer and water.
8. The nourishing and anti-dandruff shampoo as claimed in claim 1, wherein: the mass ratio of the conditioner to the surfactant is 1: 1.0-1.2.
9. The nourishing and anti-dandruff shampoo as claimed in claim 1, wherein: the mass ratio of the conditioner to the surfactant is 1: 1.0-1.05.
10. A method for preparing a nourishing type anti-dandruff shampoo as claimed in any one of claims 1 to 8, which is characterized in that: the method comprises the following steps:
(1) adding the conditioner and water with the formula dosage into a stirring pot, soaking for 30 minutes, adding the surfactant and the antistatic agent, slowly stirring, heating to 85 ℃, keeping the temperature, stirring for 30 minutes, adding the thickening agent, the pH conditioner, the preservative and the chelating agent, continuing to keep the temperature, stirring for 30 minutes, and cooling after the components are uniformly dissolved;
(2) when the temperature is reduced to 45 ℃, adding essence and a softener, uniformly stirring, and continuously reducing to room temperature to obtain the nourishing anti-dandruff shampoo.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114668695A (en) * 2022-03-26 2022-06-28 广州市金翔化妆品有限公司 Anti-dandruff composition, shampoo containing anti-dandruff composition and preparation method of shampoo

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JP2002020243A (en) * 2000-07-06 2002-01-23 Lion Corp Agent for preventing and improving gray hair
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Publication number Priority date Publication date Assignee Title
JP2002020243A (en) * 2000-07-06 2002-01-23 Lion Corp Agent for preventing and improving gray hair
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CN112043647A (en) * 2020-10-16 2020-12-08 湖南金昌生物技术有限公司 Formula and preparation process of smoothing and anti-dandruff tea bran shampoo

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114668695A (en) * 2022-03-26 2022-06-28 广州市金翔化妆品有限公司 Anti-dandruff composition, shampoo containing anti-dandruff composition and preparation method of shampoo
CN114668695B (en) * 2022-03-26 2023-01-20 广州市金翔化妆品有限公司 Anti-dandruff composition, shampoo containing anti-dandruff composition and preparation method of shampoo

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