CN110141541A - A kind of anti-dandruff and itching-relieving scalp conditioning liquid and its preparation method and application - Google Patents
A kind of anti-dandruff and itching-relieving scalp conditioning liquid and its preparation method and application Download PDFInfo
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9761—Cupressaceae [Cypress family], e.g. juniper or cypress
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Abstract
The present invention provides a kind of anti-dandruff and itching-relieving scalp conditioning liquid and its preparation method and application, and the anti-dandruff and itching-relieving scalp conditioning liquid includes chamomile essential oil, camellia flower extract, needle juniper berry extract and card slave's card leaf extract.Anti-dandruff and itching-relieving scalp conditioning liquid of the invention, using Four Plants extract, effectively performance anti-dandruff and itching-relieving, restraining and sterilizing bacteria, moisturizing, anti-oxidant four aspects effect, while mutually synergy are to realize timely and effectively scalp anti-dandruff and itching-relieving opsonic action.
Description
Technical field
The invention belongs to daily cosmetics field, it is related to a kind of anti-dandruff and itching-relieving scalp conditioning liquid and preparation method thereof and answers
With.
Background technique
The study found that at present in China, improves the dandruff hair oil head scalp problems such as itch and have become that consumer is maximum to tell
It asks, therefore anti-dandruff and itching-relieving product occupies a large amount of market, but anti-dandruff and itching-relieving used by the anti-dandruff product on domestic and international market
Agent is mostly chemical synthesis substance such as zinc pyrithione (ZPT), piroctone olamine salt (OCT) etc., these substances exist very much
Drawback, such as certain sensitization, irritation and unstability, and easily recurred after stopping using.With environmentally friendly, low in recent years
The prevalence of carbon, green and natural tendency has the products such as hair-washing hair-care currently on the market and declares that plant is anti-dandruff.But it shows according to investigations
Show, declares the anti-dandruff product overwhelming majority of plant in the market or based on chemical anti-dandruff agent, in conjunction with a small amount of plant anti-dandruff component,
And product is really then considerably less with the effective anti-dandruff and itching-relieving efficacies of natural plant extracts performance, existing market is really realized anti-dandruff
The product that antipruritic scalp improves effect is very few.
CN102429843A discloses biological environmental production anti-dandruff and itching-relieving shampoo and preparation method thereof, and it is sweet that ocean is added in the invention
The plant components such as chrysanthemum essential oil have preferable anti-dandruff and itching-relieving efficacies, but can added plant component be complicated, and realize for a long time
Conditioning effect it is on the knees of the gods.
CN108403495A discloses a kind of camellia flower extract and the Chinese herbal medicine cosmetic comprising the camellia flower extract,
Added camellia flower extract can effectively remove free radical in the invention, antioxidant and anti-aging effect, but it is for head
The effect of skin relieving itching and removing dandruff is not studied directly.
CN108904402A discloses a kind of Hair-loss-preventingshampoo shampoo, is containing mass percentage in the shampoo formula
3%~10% Anti-hair loss active constituent, the Anti-hair loss active constituent is by grape seed extract, hamamelis extract, camellia
Flower extract and camomile extract composition.Added camomile extract plays the role of anti-inflammatory, anti-anaphylaxis and sterilization in the invention,
Camellia flower extract has the effective removing oxidation resistant effect of free radical, but the formula acts on simultaneously scalp relieving itching and removing dandruff
It is not studied directly, the improvement of the unimpeded aspect of seborrhea and pore for scalp is also general.
CN109223622A discloses a kind of compound essential oil for reducing alopecia, is made of the component of following parts by weight: fan changes
15-20 parts of essential oil, 12-15 parts of cupressus sempervirens essential oil, 10-12 parts of needle juniper fruit essential oil, flower essential oil 10-15 parts of Yilan, north African
12-15 parts of deodar bark absolute oil, 55-70 parts of plant base oil.Added needle juniper fruit essential oil has sterilization reconciliation in the invention
Effect of poison, but added plant component is complicated, and moisture-retaining capacity is poor, and antioxidant and anti-aging effect is not also carried out
Direct research.
Therefore it provides one kind can either anti-dandruff and itching-relieving, restraining and sterilizing bacteria in time, while the oxidation resistant head of moisturizing can be played again
The scalp conditioning liquid of skin opsonic action has great importance and vast market prospect in daily cosmetics field.
Summary of the invention
In view of the deficiencies of the prior art, the purpose of the present invention is to provide a kind of anti-dandruff and itching-relieving scalp conditioning liquid and its preparations
Methods and applications, the scalp conditioning formula of liquid are synergistic to realize by using Four Plants extract, while mutually
Timely and effectively scalp anti-dandruff and itching-relieving opsonic action.
To achieve this purpose, the present invention adopts the following technical scheme:
In a first aspect, the present invention provides a kind of anti-dandruff and itching-relieving scalp conditioning liquid, the conditioning liquid includes chamomile essential oil, mountain
Flos Camelliae Japonicae extract, needle juniper berry extract and card slave's card leaf extract.
In the present invention, the chamomile essential oil of compositae plant has stronger antioxidation, while having and relaxing well
Quick, the sensitive skin of maintenance reduces thin red capillary, reduces the effects of rubescent, is rich in flavones saponin(e, polysaccharide and volatile oil isoreactivity
Ingredient, these active constituents have anti-oxidant, anti-inflammatory, anti-allergy and antiviral effect, can quickly pacify rubescent skin, right
The skin easily itched has good soothing effect；Camellia flower extract extracts the flower that source is camellia section plant camellia, contains
There are the ingredients such as flavones, saponin(e, catechuic acid, vitamin C, tannic acid and amino acid abundant, there is antibacterial, free radical resisting antioxygen
Change, Bergamot Mint Extract, helps the effect for improving scalp grease balance；Needle juniper berry extract not only purifying skin, it is antibacterial, convergence
Effect it is prominent, and there are detoxicating functions, the pore of acne and obstruction can be effectively improved, reach deep layer cleaning purification, change
The seborrhea and other effects of kind scalp；Blocking slave's card leaf extract has the energy for reducing sebum amount and processing acne that sebaceous glands generates
Power, while can also quickly make pore unimpeded under the synergistic effect of camellia flower extract.
Contain chamomile essential oil, camellia flower extract, needle juniper berry extract and the anti-dandruff and itching-relieving head for blocking slave's card leaf extract
Skin conditioning liquid, each functional components also unexpectedly show synergy in addition to playing basic effect possessed by itself
Effect effectively mostly can add chemical anti-dandruff agent for anti-dandruff and itching-relieving product in washing shield product or a little plant of collaboration is anti-dandruff
Ingredient, it is existing stop using after recur, be easy to develop drug resistance, chemical anti-dandruff agent leads to scalp microenvironment, microbial environment
Imbalance, and then cause more scalp problems and hair problem etc., while solving the problems, such as that head is itched and being difficult to the problem of eradicating in time.It is comprehensive
The upper present invention uses Four Plants extract, can effectively play anti-dandruff and itching-relieving, restraining and sterilizing bacteria, moisturizing, anti-oxidant four aspects
Effect, at the same it is mutually synergistic to realize timely and effectively scalp anti-dandruff and itching-relieving opsonic action.
In the present invention, the conditioning liquid includes: chamomile essential oil 0.5-5.0%, camellia extraction by weight percentage
Object 0.5-5.0%, needle juniper berry extract 0.5-5.0% and card slave's card leaf extract 0.5-5.0%.
Preferably, weight percent of the chamomile essential oil in the conditioning liquid is 0.5-5.0%, such as be can be
0.5%, 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, 2.2%, 2.4%, 2.6%,
2.8%, 3.0%, 3.2%, 3.4%, 3.6%, 3.8%, 4.0%, 4.2%, 4.4%, 4.6%, 4.8%, 5.0%.
Preferably, weight percent of the camellia flower extract in the conditioning liquid is 0.5-5.0%, such as can be with
0.5%, 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, 2.2%, 2.4%, 2.6%,
2.8%, 3.0%, 3.2%, 3.4%, 3.6%, 3.8%, 4.0%, 4.2%, 4.4%, 4.6%, 4.8%, 5.0%.
Preferably, weight percent of the needle juniper berry extract in the conditioning liquid is 0.5-5.0%, such as can be with
0.5%, 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, 2.2%, 2.4%, 2.6%,
2.8%, 3.0%, 3.2%, 3.4%, 3.6%, 3.8%, 4.0%, 4.2%, 4.4%, 4.6%, 4.8%, 5.0%.
Preferably, weight percent of the card slave's card leaf extract in the conditioning liquid is 0.5-5.0%, such as can
Be 0.5%, 0.6%, 0.8%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, 2.2%, 2.4%, 2.6%,
2.8%, 3.0%, 3.2%, 3.4%, 3.6%, 3.8%, 4.0%, 4.2%, 4.4%, 4.6%, 4.8%, 5.0%.
In the present invention, the conditioning liquid further include in permeation enhancers, moisturizer or aromatic any one or at least
Two kinds of combination.
Preferably, weight percent of the permeation enhancers in the anti-dandruff and itching-relieving scalp conditioning liquid is 10-60%, example
It such as can be 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%.
Preferably, the permeation enhancers be ethyl alcohol, ethylene glycol, in menthol any one or at least two combination,
Preferably ethyl alcohol.
In the present invention, permeation enhancers can be improved or conditioning liquid is accelerated to penetrate through skin, promote the absorption of effective substance.
It is preferred that penetration enhancer is ethyl alcohol, the absorption of effective substance can be advantageously promoted, and faint, nothing is stimulated to skin zero damage
Anaphylaxis, stable in physicochemical property, and have good compatibility with the conditioning liquid containing Four Plants extract, rapid-action, effect
Time is long.
Preferably, weight percent of the moisturizer in the anti-dandruff and itching-relieving scalp conditioning liquid is 0.01-5%, example
Such as can be 0.01%, 0.1%, 0.5%, 1.0%, 1.2%, 1.4%, 1.6%, 1.8%, 2.0%, 2.2%, 2.4%,
2.6%, 2.8%, 3.0%, 3.2%, 3.4%, 3.6%, 3.8%, 4.0%, 4.2%, 4.4%, 4.6%, 4.8%,
5.0%.
Preferably, the moisturizer be panthenol, it is xylitol, hexylene glycol, butanediol, glycerol, macromolecular Sodium Hyaluronate, small
In numerator sodium hyaluronate or aloe extract any one or at least two combination.
Preferably, the moisturizer is the combination of panthenol, xylitol and hexylene glycol.
In the present invention, moisturizer is by absorbing and keeping moisture to reach moisturizing, moist, recovery elasticity of skin and other effects.
Especially panthenol, xylitol, they have efficient mild moisturizing effect, and in addition to this there are also hexylene glycols, or without anti-corrosion
Anti-corrosion in agent prescription substitutes ingredient, is both that moisturizer has born antisepsis again.Four in the moisturizer collaboration present invention
Plant Extracts, be better achieved scalp moisturization moisturizing, cleaning, it is anti-oxidant, sterilization releive, Sage Extract effect.
Preferably, the moisturizer includes with the conditioning liquid total weight for absolutely panthenol 0.05-0.3%, wood
Sugar alcohol 0.01-0.3% and hexylene glycol 0.1-1.2%.
Preferably, weight percent of the panthenol in the conditioning liquid is 0.05-0.3%, such as be can be
0.05%, 0.06%, 0.08%, 0.10%, 0.12%, 0.14%, 0.16%, 0.18%, 0.20%, 0.22%, 0.24%,
0.26%, 0.28%, 0.30%.
Preferably, weight percent of the xylitol in the conditioning liquid is 0.05-0.3%, such as be can be
0.05%, 0.06%, 0.08%, 0.10%, 0.12%, 0.14%, 0.16%, 0.18%, 0.20%, 0.22%, 0.24%,
0.26%, 0.28%, 0.30%.
Preferably, weight percent of the hexylene glycol in the conditioning liquid is 0.1-1.2%, such as be can be
0.10%, 0.15%, 0.20%, 0.25%, 0.30%, 0.35%, 0.40%, 0.45%, 0.50%, 0.55%, 0.60%,
0.65%, 0.70%, 0.75%, 0.80%, 0.85%, 0.90%, 1.0%, 1.2%.
Preferably, weight percent of the aromatic in the anti-dandruff and itching-relieving scalp conditioning liquid is 0.05%-
0.15%, for example, can be 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.10%, 0.11%, 0.12%,
0.13%, 0.14%, 0.15%.
In the present invention, the scalp conditioning liquid includes: that chamomile essential oil 0.5-5.0%, camellia mention by weight percentage
Take object 0.5-5.0%, needle juniper berry extract 0.5-5.0%, card slave's card leaf extract 0.5-5.0%, permeation enhancers 10-60%,
Moisturizer 0.01-5.0%, aromatic 0.05-0.15%, surplus are deionized water.
In the present invention, the scalp conditioning liquid includes: ethyl alcohol 10-60%, chamomile essential oil 0.5- by weight percentage
5.0%, camellia flower extract 0.5-5.0%, needle juniper berry extract 0.5-5.0%, card slave's card leaf extract 0.5-5.0%, general
Alcohol 0.05-0.3%, xylitol 0.01-0.3%, hexylene glycol 0.1-1.2%, aromatic 0.05-0.15%, surplus are deionization
Water.
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.0%, needle juniper fruit by weight percentage
Extract 2.0%, camellia flower extract 2.0%, card slave's card leaf extract 2.0%, panthenol 0.15%, xylitol 0.1%, oneself two
Alcohol 1.0%, aromatic 0.1%, surplus are deionized water.
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.5%, needle juniper fruit by weight percentage
Extract 1.5%, camellia flower extract 2.0%, card slave's card leaf extract 2.0%, panthenol 0.15%, xylitol 0.1%, oneself two
Alcohol 1.0%, aromatic 0.1%, surplus are deionized water.
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.0%, needle juniper fruit by weight percentage
Extract 2.0%, camellia flower extract 1.5%, card slave's card leaf extract 2.5%, panthenol 0.15%, xylitol 0.1%, oneself two
Alcohol 1.0%, aromatic 0.1%, surplus are deionized water.
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.5%, needle juniper fruit by weight percentage
Extract 2.5%, camellia flower extract 1.5%, card slave's card leaf extract 1.5%, panthenol 0.15%, xylitol 0.1%, oneself two
Alcohol 1.0%, aromatic 0.1%, surplus are deionized water.
Second aspect, the present invention provides a kind of preparation method of anti-dandruff and itching-relieving scalp conditioning liquid as described in relation to the first aspect,
The preparation method is that: chamomile essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf extract are mixed, stirred
It mixes and uniformly obtains the anti-dandruff and itching-relieving scalp conditioning liquid.
Preferably, permeation enhancers, chamomile essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf are extracted
Object mixing, is uniformly mixing to obtain the anti-dandruff and itching-relieving scalp conditioning liquid after supplying moisture.
Preferably, permeation enhancers, chamomile essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf are extracted
Object mixing, is then added moisturizer and aromatic, is uniformly mixing to obtain the anti-dandruff and itching-relieving scalp conditioning liquid after supplying moisture.
The third aspect, the present invention provides a kind of anti-dandruff and itching-relieving scalp conditioning liquids as described in relation to the first aspect in hair products
Application.
In the present invention, additive amount of the conditioning liquid in hair products is the 0.1- of hair products total weight
30%, for example, can be 0.1%, 0.5%, 1%, 2%, 4%, 6%, 10%, 12%, 14%, 16%, 18%, 20%,
22%, 24%, 26%, 28%, 30%, preferably 15%.
In the present invention, the hair products include shampoo, hair conditioner, hair film, hair oil or take care of hair any in by spraying
One kind, preferably shampoo.
Compared with the existing technology, the invention has the following advantages:
(1) present invention uses Four Plants extract, can effectively play anti-dandruff and itching-relieving, restraining and sterilizing bacteria, moisturizing, anti-oxidant
Four aspect effects, it is mutually synergistic to realize timely and effectively scalp anti-dandruff and itching-relieving opsonic action: the scalp conditioning liquid
In to chlosma bacteriostasis test process, obtained antibacterial circle diameter is up to 18.38mm；Clear using DPPH free radical
When being tested except power, the antioxidant DPPH clearance rate of conditioning liquid of the present invention is up to 75% or more；For keeping scalp moisture side
Mask has greatly improved, and remains to reach 23% or more using scalp moisture content after 12h；In anti-dandruff and itching-relieving scalp conditioning liquid to reality
Border finds that it can timely and effectively improve people of the scalp to achieve the effect that anti-dandruff and itching-relieving, suitable for most of age bracket when testing
Group.
(2) anti-dandruff and itching-relieving scalp conditioning liquid of the present invention, the anti-oxidant anti-inflammatory of flavones ingredient contained by chamomile essential oil
It is antipruritic, quickly pacify sensitive rubescent skin, mild moisturizing, skin of releiving；Needle juniper berry extract is softly cleaned, restrains, is sterilized, and is changed
Kind sebum microenvironment；Camellia flower extract, card slave's card leaf extract effectively play bacteriostasis antibiosis effect；In conjunction with panthenol, xylitol
Efficient mild moisturizing, ethanol in proper amount promotes the absorption of effective substance, realizes that antipruritic, restraining and sterilizing bacteria, the conditioning of anti-dandruff, scalp are made in time
With.
(3) anti-dandruff and itching-relieving scalp conditioning liquid of the present invention can not only be improved due to its extremely weak irritation separately as scalp
Liquid also can be applied to the hair washing such as shampoo, hair conditioner, scalp Essence, take care of hair, in scalp care product outside.
Detailed description of the invention
Fig. 1 is Scavenging activity test result figure of the scalp conditioning liquid to DPPH free radical.
Fig. 2 is scalp moisture content test result statistical chart.
Specific embodiment
The technical scheme of the invention is further explained by means of specific implementation.Those skilled in the art should be bright
, the described embodiments are merely helpful in understanding the present invention, should not be regarded as a specific limitation of the invention.
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It is not limitation of the present invention.Unless stated otherwise, content described in embodiment is mass percentage content.It is not specified specific
The experimental method of condition, usually according to normal condition or manufacturer's recommendations condition carries out.
Embodiment 1-4
The anti-dandruff and itching-relieving scalp conditioning liquid of the present embodiment 1-4, (number represents weight to weight percent i.e. in table as shown in Table 1
Percentage is measured, such as 30 components that represent 30%) are made.
Table 1
Anti-dandruff and itching-relieving scalp conditioning liquid described in any of the above-described embodiment 1-4 the preparation method comprises the following steps: by formula ratio by second
Alcohol, chamomile essential oil, needle juniper berry extract, camellia flower extract, card slave's card leaf extract be mixed, then be added panthenol,
Xylitol, hexylene glycol and aromatic stir evenly after supplying moisture.
Comparative example 1-6
The scalp conditioning liquid of this comparative example 1-6, the component of weight percent is made as shown in Table 2, preparation method with it is above-mentioned
The preparation method of anti-dandruff and itching-relieving scalp conditioning liquid described in any one embodiment 1-4 is identical.
Table 2
Embodiment 5
The antibacterial test of chlosma is carried out to the scalp conditioning liquid of embodiment 1-5 and comparative example 1-6 in the present embodiment
The present embodiment recommends the instruction experiment of Odontothrips loti inhibition zone referring to U.S. clinical standard committee (NCCLS): sterile
Under the conditions of, it draws 200 μ L indicator bacteria uniform suspensions and is coated on plating medium；0.1mL is added dropwise respectively to Oxford cup by reality
Apply the sample solution of a 1-4 Yu comparative example 1-6, wherein indicator bacteria is that the culture of chlosma is based on 37 DEG C of culture 48h；It removes
Oxford cup compares fungistatic effect with the diameter of each inhibition zone of vernier caliper accurate measuring.
Wherein experimental strain and the bacterial concentration configured by the strain are as shown in table 1.To embodiment 1-4 and comparison
Example 1-6 carries out the antibacterial test of chlosma, using comparative example 5 as blank control group.It takes 0.1mL to be tested respectively, lists
All given the test agent are 1.0 × 106Fungistatic effect analysis under cfu/g bacterial concentration is as a result, as shown in table 3.
Table 3
| Test sample | Antibacterial circle diameter/mm | Whether result judgement (has fungistatic effect) |
| Embodiment 1 | 17.13 | There is apparent inhibition zone |
| Embodiment 2 | 16.34 | There is apparent inhibition zone |
| Embodiment 3 | 17.76 | There is apparent inhibition zone |
| Embodiment 4 | 18.38 | There is apparent inhibition zone |
| Comparative example 1 | 12.86 | There is certain bacteriostasis |
| Comparative example 2 | 15.03 | There is apparent inhibition zone |
| Comparative example 3 | 15.34 | There is apparent inhibition zone |
| Comparative example 4 | 13.31 | There is certain bacteriostasis |
| Comparative example 5 (blank control) | 5.85 | Faint bacteriostasis |
| Comparative example 6 | 15.11 | There is apparent inhibition zone |
By table 3 statistics indicate that, embodiment 1-4 have apparent chlosma bacteriostasis, comparative example 2, comparative example 3
With preferable bacteriostasis, this illustrates individual chamomile essential oil and needle juniper berry extract, and there is also certain chlosmas to inhibit
Effect, but the bacteriostasis of individual plant extracts contains the suppression of the conditioning liquid of Four Plants extract than embodiment 1-4
Bacterium effect wants low；For the comparative example 6 for lacking card slave's card leaf extract, there is also certain bacteriostasis, but
It is effect not as good as embodiment 1-4 sample bacteriostasis, illustrates chamomile essential oil, needle juniper berry extract, the collaboration of camellia flower extract
Card slave's card leaf extract, which is formed by system, can play synergistic effect more effectively to which that better chlosma is presented is antibacterial
Effect, the chlosma bacteriostasis having especially with embodiment 3,4 is the most excellent, and antibacterial circle diameter respectively reaches 17.76mm
And 18.38mm.
Embodiment 6
In the present embodiment, DPPH radicals scavenging survey is carried out to the scalp conditioning liquid of embodiment 1-4 and comparative example 1-6
Examination
Test philosophy are as follows: DPPH is a kind of stable organic free radical, and most strong absworption peak is in 519nm, this free radical
Darkviolet can be shown after ethanol solution is added, and when a certain amount of antioxidant is added, antioxidant can be measured at 519nm
Absorbance value after removing lighter caused by DPPH.Quantitative analysis is carried out using spectrophotometry, to detect free radical
Situation is removed, to evaluate the ability that the active constituent in product with anti-oxidation efficacy removes free radical, clearance rate is bigger, then
Show that its removing free radical oxidation resistance is stronger, wherein blank sample DPPH clearance rate is 0.Finally obtain scalp conditioning liquid pair
The Scavenging activity test result of DPPH free radical, as shown in Figure 1.
By Fig. 1's, statistics indicate that, the anti-dandruff and itching-relieving scalp conditioning liquid in embodiment 1-4 containing Four Plants extract has
Potent Scavenging ability, embodiment 1,4 scalp conditioning liquid of embodiment have better advantage in terms of removing free radical.It is right
Ratio 1 can equally play preferable effect of scavenging radical, and chamomile essential oil has preferable effect of scavenging radical；Comparative example
6 without card slave's card leaf extract scalp conditioning liquid there is stronger radicals scavenging effect but its scavenging effect to be weaker than embodiment 1-
4 scalp conditioning liquids show that card slave's card leaf extract can cooperate with chamomile essential oil, needle juniper berry extract, camellia flower extract to increase
The radicals scavenging power of strong system；And the radicals scavenging power of the system of embodiment 1-4 is generally higher than comparative example 1-6, illustrates to apply
It turns round after skin conditioning liquid, there is better advantage in terms of removing free radical, chamomile essential oil, needle juniper berry extract, camellia mention
It takes object and blocks effect of the removing free radical aspect than being used alone or lacking a component after these four substances of slave's card leaf extract compounding
Fruit is good, plays synergistic function.
Embodiment 7
Anti-dandruff and itching-relieving Contrast on effect is carried out to the scalp conditioning liquid of embodiment 1-4 and comparative example 1-6 in the present embodiment
Evaluation
There are problems that head is itched or/and dandruff volunteer carries out embodiment 1-4, comparative example 1-6 scalp conditioning liquid to 270,
Scalp spraying test is carried out, is tried out 2 months time, daily to spray, the symmetrical area in the left side is adopted as comparative example 5 as control, the right
Compared for anti-dandruff and itching-relieving scalp conditioning liquid is on probation, every group of 30 people, to itched during two months using back and dandruff situation into
Row evaluation record, comparative analysis find that anti-dandruff and itching-relieving scalp conditioning liquid of the present invention itches problem improvement shape to volunteer's dandruff and head
Condition, the results are shown in Table 4.
Table 4
Embodiment 8
Scalp moisturization aptitude tests
This test is referring to light industry standard " cosmetics moisture-keeping efficacy evaluation guide " to embodiment 1-4 and comparative example 1-6
Carry out moisture-keeping efficacy test；The principle of the method is: the moisture content using capacitance method measurement human skin keratinocyte's layer is to be based on
The difference in dielectric constant of water and other substances is significant, according to the difference of keratoderma moisture content, the capacitor of the skin measured
Value is different, and parameter can represent scalp moisture levels.
Using opinion poll point system, choose the people of 130 25-65 years old age brackets as object on probation, recipient site without
Any exception, entire test process are carried out in laboratory with constant temperature and constant humidity, and room temperature is 20 ± 2 DEG C, humidity 50-60%；It is divided into 4
Group, every group of 30 people use embodiment 1-4 scalp conditioning liquid respectively；Using half a head control methods, the left side: it is not added with chamomile essence
Oil, needle juniper berry extract, camellia flower extract and block slave's card leaf extract common aqua conditioning liquid (other raw material additive amounts with
It is consistent that Application Example scalp improves formula of liquid), the right: embodiment 1-4 scalp conditioning liquid；Using the skin water of German CK company
Tester Corneometer CM825 is divided to carry out scalp moisturization detection；Numerical value is bigger, shows that water content of stratum corneum is higher；To making
It is tested with rear 1h, 4h, 8h, 12h moisture content of skin, its average value is taken to map, the scalp moisture of different time measurement
Content results statistical chart is as shown in Figure 2.
As shown in Figure 2, as time increases, the tested region water content of blank control group is without significant change, and implements
Water content testing result of the example 1-4 scalp conditioning liquid after use in 12h shows that embodiment 1-4 scalp conditioning liquid is in holding head
The severe edema due to hypofunction of the spleen point aspect tool has greatly improved, and the moisture content of embodiment 1-4 is generally higher than comparative example 1-6, illustrates to smear scalp
After conditioning liquid, the moisture content of scalp all be increased, and have certain moisture retention, and chamomile essential oil, needle juniper berry extract,
Moistening effect after camellia flower extract and card these four substances of slave's card leaf extract compounding is than being used alone or lacking a component
Effect is good, plays synergistic function.Embodiment 2, embodiment 4 have better scalp moisturization effect, after use in 12h
Water content testing result be respectively 27.6% and 26.3%.
Embodiment 9
Scalp conditioning liquid irritation-erythrocyte hemolysis test
Erythrocyte hemolysis test method: rabbit is replaced using erythrocyte hemolysis experiment (Red blood cell test RBC)
Eye irritation experiment carries out eye irritation assessment to scalp conditioning liquid mildness, and basic principle is by measurement chemicals to cell
The damage (haemolysis) of film and damage (hemoglobin denaturation) degree to hemoglobin evaluate the eye irritation of tested material.It is international
On mainly by RBC experiment be used for the chemicals such as cosmetic product and raw material eye irritation study.Therefore the present invention passes through red thin
Cell lysis blood experimental method measures the mildness of formula, and is contrasted, evaluating product mildness.It calculates and causes at 410nm
The A value ratio under tested material weight concentration (HC50, mg/L) and 575,540nm wavelength when haemolysis occurs for 50% red blood cell obtains
Hemoglobin denaturation rate (DI), and calculate the ratio L/D (L50/DI) of 2 variables, embodiment 1-4 provided by the invention with
And after the shampoo of Comparison study example 1-6 offer is tested, obtained L/D value is as shown in table 5.
Table 5
| Tested material | L/D | Irritation grade |
| Embodiment 1 | 86 | Mired irritation |
| Embodiment 2 | 94 | Mired irritation |
| Embodiment 3 | 79 | Mired irritation |
| Embodiment 4 | 67 | Mired irritation |
| Comparative example 1 | 37 | Mired irritation |
| Comparative example 2 | 56 | Mired irritation |
| Comparative example 3 | 32 | Mired irritation |
| Comparative example 4 | 24 | Mired irritation |
| Comparative example 5 (blank control) | 9 | Slight stimulation |
| Comparative example 6 | 69 | Mired irritation |
Cell hemolytic experiment statistics indicate that, chamomile essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf mention
Take object to be formed by scalp conditioning liquid system irritation low, at the same when four kinds of substances exist simultaneously its irritation significantly lower than independent
A kind of irritation of extract, card slave's card leaf extract cooperate other three Plant Extracts to play very in terms of reducing irritation
Good synergistic effect.
In conclusion chamomile essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf extract are formed by
Anti-dandruff and itching-relieving scalp conditioning liquid has anti-dandruff and itching-relieving, inhibits chlosma, anti-oxidant, moisture-keeping function, while chamomile essential oil, Du
There are potent synergistic effects for pine cone extract, camellia flower extract and card slave's card leaf extract.
The Applicant declares that the present invention is explained by the above embodiments method detailed of the invention, but the present invention not office
It is limited to above-described embodiment, that is, does not mean that the present invention must rely on above-described embodiment and could implement.The technology of technical field
Personnel it will be clearly understood that any improvement in the present invention, the addition of equivalence replacement and auxiliary element to each raw material of product of the present invention,
The selection etc. of concrete mode, all of which fall within the scope of protection and disclosure of the present invention.
Claims (10)
1. a kind of anti-dandruff and itching-relieving scalp conditioning liquid, which is characterized in that the conditioning liquid includes chamomile essential oil, camellia extraction
Object, needle juniper berry extract and card slave's card leaf extract.
2. anti-dandruff and itching-relieving scalp conditioning liquid according to claim 1, which is characterized in that the conditioning liquid is by weight percentage
It include: chamomile essential oil 0.5-5.0%, camellia flower extract 0.5-5.0%, needle juniper berry extract 0.5-5.0% and card slave's card
Leaf extract 0.5-5.0%.
3. anti-dandruff and itching-relieving scalp conditioning liquid according to claim 1 or 2, which is characterized in that the conditioning liquid further includes promoting
In bleeding agent, moisturizer or aromatic any one or at least two combination；
Preferably, weight percent of the permeation enhancers in the anti-dandruff and itching-relieving scalp conditioning liquid is 10-60%；
Preferably, the permeation enhancers be ethyl alcohol, ethylene glycol, in menthol any one or at least two combination, preferably
For ethyl alcohol；
Preferably, weight percent of the moisturizer in the anti-dandruff and itching-relieving scalp conditioning liquid is 0.01-5%；
Preferably, the moisturizer is panthenol, xylitol, hexylene glycol, butanediol, glycerol, macromolecular Sodium Hyaluronate, small molecule
In Sodium Hyaluronate or aloe extract any one or at least two combination；
Preferably, the moisturizer is the combination of panthenol, xylitol and hexylene glycol；
Preferably, the moisturizer includes with the conditioning liquid total weight for absolutely panthenol 0.05-0.3%, xylitol
0.01-0.3% and hexylene glycol 0.1-1.2%；
Preferably, weight percent of the aromatic in the anti-dandruff and itching-relieving scalp conditioning liquid is 0.05%-0.15%.
4. anti-dandruff and itching-relieving scalp conditioning liquid according to any one of claim 1-3, which is characterized in that the scalp conditioning
Liquid includes: chamomile essential oil 0.5-5.0%, Flos Camelliae Japonicae extract 0.5-5.0%, needle juniper berry extract 0.5- by weight percentage
5.0%, block slave's card leaf extract 0.5-5.0%, permeation enhancers 10-60%, moisturizer 0.01-5.0%, aromatic 0.05-
0.15%, surplus is deionized water.
5. anti-dandruff and itching-relieving scalp conditioning liquid described in any one of -4 according to claim 1, which is characterized in that the scalp conditioning
Liquid includes: ethyl alcohol 10-60%, chamomile essential oil 0.5-5.0%, camellia flower extract 0.5-5.0%, needle juniper by weight percentage
Berry extract 0.5-5.0%, card slave's card leaf extract 0.5-5.0%, panthenol 0.05-0.3%, xylitol 0.01-0.3%, oneself
Glycol 0.1-1.2%, aromatic 0.05-0.15%, surplus are deionized water；
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.0%, the extraction of needle juniper fruit by weight percentage
Object 2.0%, camellia flower extract 2.0%, card slave's card leaf extract 2.0%, panthenol 0.15%, xylitol 0.1%, hexylene glycol
1.0%, aromatic 0.1%, surplus are deionized water；
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.5%, the extraction of needle juniper fruit by weight percentage
Object 1.5%, camellia flower extract 2.0%, card slave's card leaf extract 2.0%, panthenol 0.15%, xylitol 0.1%, hexylene glycol
1.0%, aromatic 0.1%, surplus are deionized water；
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.0%, the extraction of needle juniper fruit by weight percentage
Object 2.0%, camellia flower extract 1.5%, card slave's card leaf extract 2.5%, panthenol 0.15%, xylitol 0.1%, hexylene glycol
1.0%, aromatic 0.1%, surplus are deionized water；
Preferably, the scalp conditioning liquid includes: ethyl alcohol 30%, chamomile essential oil 2.5%, the extraction of needle juniper fruit by weight percentage
Object 2.5%, camellia flower extract 1.5%, card slave's card leaf extract 1.5%, panthenol 0.15%, xylitol 0.1%, hexylene glycol
1.0%, aromatic 0.1%, surplus are deionized water.
6. a kind of preparation method of the anti-dandruff and itching-relieving scalp conditioning liquid as described in any one of claim 1-5, which is characterized in that institute
It states the preparation method comprises the following steps: chamomile essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf extract are mixed, stirring
Uniformly obtain the anti-dandruff and itching-relieving scalp conditioning liquid.
7. preparation method according to claim 6, which is characterized in that the preparation method is that: by permeation enhancers, chamomile
Essential oil, needle juniper berry extract, camellia flower extract and card slave's card leaf extract mixing, supply be uniformly mixing to obtain after moisture it is described
Anti-dandruff and itching-relieving scalp conditioning liquid；
Preferably, the preparation method is that: by permeation enhancers, chamomile essential oil, needle juniper berry extract, camellia flower extract and card
The mixing of slave's card leaf extract, is then added moisturizer and aromatic, is uniformly mixing to obtain the anti-dandruff and itching-relieving head after supplying moisture
Skin conditioning liquid.
8. a kind of application of anti-dandruff and itching-relieving scalp conditioning liquid according to any one of claims 1 to 5 in hair products.
9. application according to claim 8, which is characterized in that additive amount of the conditioning liquid in hair products is hair care
The 0.1-30% of product total weight, preferably 15%.
10. application according to claim 8 or claim 9, which is characterized in that the hair products include shampoo, hair conditioner, hair
Film, hair oil or any one taken care of hair in by spraying, preferably shampoo.
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