CN110840754B

CN110840754B - Anti-dandruff oil-control shampoo and preparation method thereof

Info

Publication number: CN110840754B
Application number: CN201911188347.2A
Authority: CN
Inventors: 陈武辉
Original assignee: Guangzhou Fayasi Fine Chemical Co ltd
Current assignee: Guangzhou Fayasi Fine Chemical Co ltd
Priority date: 2019-11-28
Filing date: 2019-11-28
Publication date: 2020-08-04
Anticipated expiration: 2039-11-28
Also published as: CN110840754A

Abstract

The invention provides an anti-dandruff oil-control shampoo and a preparation method thereof, and relates to the field of daily chemicals. The shampoo prepared from the raw materials has excellent effects on removing dandruff and controlling oil, is high in safety, cannot generate stimulation and sensitization, and is good in public experience.

Description

Anti-dandruff oil-control shampoo and preparation method thereof

Technical Field

The invention relates to the field of daily chemicals, and particularly relates to an anti-dandruff oil-control shampoo and a preparation method thereof.

Background

Dandruff is the exfoliative keratinocytes of the scalp. Normally, the keratinocyte is little and slow to fall off and can not be obviously seen, but under certain stimulation, a large amount of immature keratinocyte is generated, and cakes fall off; the scalp oil is greasy phenomenon caused by the damaged ecological balance of scalp and unbalanced scalp oil secretion. The existing shampoo is often milky and highly viscous emulsion, is difficult to clean or has the problems of skin irritation, sensitization, toxicity or poor persistence and the like.

Chinese patent CN106236659A discloses an anti-dandruff oil-control shampoo, which is prepared by conventionally mixing the following raw materials in percentage by weight: 21 percent of sodium laureth sulfate, 3.2 percent of extract of the root of lightyellow sophora root, 3.5 percent of extract of cacumen biotae, 2.2 percent of extract of ginger, 2 percent of cocoamide, 0.8 percent of ethylene glycol distearate, 0.6 percent of cetyl stearyl alcohol, 4.5 percent of cocamidopropyl betaine, 0.5 percent of guar hydroxypropyltrimonium chloride, 100.2 percent of polyquaternium, 0.05 percent of sodium hyaluronate, 0.1 percent of citric acid, 0.25 percent of sodium citrate, 0.35 percent of bipyridinethione, 1.2 percent of dimethiconol, 61.5 percent of vitamin B, 0.2 percent of carbomer, 0.5 percent of panthenol, 0.1 percent of methylisothiazolinone, 0.5 percent of essence, 0.1 percent of EDTA-2NA and the balance of water, and by selecting proper raw materials to form a formula, the shampoo has good effects of removing dandruff and controlling oil, good skin-friendly ability and strong penetrability, is a mild cleaning product and can better clean the shampoo and the scalp, but the shampoo of the invention can generate certain irritation to organisms, thereby affecting the sensory experience.

Chinese patent CN109568219A discloses a biological anti-dandruff antipruritic compound and application thereof, wherein the biological anti-dandruff antipruritic compound comprises the following components in percentage by mass: 2-4% of sweet wormwood herb extract, 2-4% of pseudo-ginseng root extract, 2-3% of divaricate saposhnikovia root extract, 2-3% of argy wormwood leaf extract, 2-3% of common cnidium fruit extract, 1-3% of tetrandra root extract, 1-3% of kushen root extract, 0.6% of phenoxyethanol and the balance of water. The compound agent can be used as functional raw material for preparing shampoo, hair conditioner and gel water, is rich in multiple natural compound plant polyphenols, and has effects of regulating hormone level and sebum metabolism, resisting inflammation, killing bacteria, removing dandruff and relieving itching. However, the composition of each substance in the complexing agent in the invention cannot bring better experience to the public in the aspects of smell sense and vision.

Chinese patent CN110063921A discloses a ginger nourishing shampoo and a preparation method thereof, wherein the ginger nourishing shampoo comprises the following raw materials: the shampoo is warm and low in stimulation, so that stimulation to the scalp is reduced while the scalp is cleaned, and fresh ginger extract can promote scalp blood circulation. However, the invention mainly takes ginger extract as a functional raw material, and the anti-dandruff oil control function of the invention is relatively weak.

According to the problems of poor safety, poor anti-dandruff oil control capability, complex preparation method and the like in the prior art, an anti-dandruff oil control shampoo and a preparation method thereof are sought, so that the preparation method is simple and convenient, the anti-dandruff and oil control effects of the prepared shampoo are stronger, and meanwhile, the shampoo is higher in safety, does not generate irritation and sensitization, and is better in public experience.

Disclosure of Invention

The invention provides an anti-dandruff oil-control shampoo and a preparation method thereof, aiming at the problems in the prior art. The preparation method of the shampoo is simple and convenient, the prepared shampoo has excellent effects on removing dandruff and controlling oil, and the shampoo is high in safety, does not produce irritation and sensitization, and is good in public experience.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

the invention provides an anti-dandruff oil-control shampoo which comprises the following raw materials: ginger extract, sophora flavescens root extract, clerodendranthus spicatus extract, fructus cnidii extract, propylene glycol, detergent, cocamide MEA, PCA zinc, guar hydroxypropyl trimonium chloride, polyquaternium-10, zinc pyrithione, dimethiconol, zinc gluconate, carbomer, erythritol, benzyl alcohol, sodium benzoate, ethylene glycol diphosphate, colorant, sodium hydroxide, essence and the balance of water.

Further, the anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 9-12% of ginger extract, 1.8-3% of sophora flavescens root extract, 0.8-1.5% of clerodendranthus spicatus extract, 0.2-1% of fructus cnidii extract, 0.2-0.8% of propylene glycol, 10.3-17.3% of cleaning agent, 0.8-2% of cocamide MEA, 0.2-0.8% of PCA zinc, 0.1-0.5% of guar hydroxypropyl trimonium chloride, 0.05-0.3% of polyquaternium-10, 0.2-0.6% of zinc pyrithione, 1-1.8% of dimethiconol, 0.2-0.6% of zinc gluconate, 0.1-0.5% of carbomer, 1-3% of erythritol, 0.1-0.5% of benzyl alcohol, 0.2-0.6% of sodium benzoate, 0.001-0.005% of hydroxyethyldiphosphonic acid, 0.0012-0.7% of coloring agent, 0.02-0.005% of sodium hydroxide and the balance of water essence.

Preferably, the anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 10-11% of ginger extract, 2-2.8% of sophora flavescens root extract, 1-1.4% of clerodendranthus spicatus extract, 0.3-0.8% of cnidium monnieri fruit extract, 0.3-0.5% of propylene glycol, 12.2-15.5% of cleaning agent, 1-1.8% of cocamide MEA, 0.3-0.6% of PCA zinc, 0.2-0.3% of guar hydroxypropyl trimonium chloride, 0.1-0.2% of polyquaternary ammonium salt-10, 0.3-0.5% of zinc pyrithione, 1.1-1.6% of dimethiconol, 0.3-0.55% of zinc gluconate, 0.15-0.25% of carbomer, 1.8-2.2% of erythritol, 0.2-0.4% of benzyl alcohol, 0.3-0.5% of benzene, 0.0015-0.003% of hydroxyethyl diphosphate, 0.0023-0.00355% of sodium hydroxide, 0.015-0.15% of sodium hydroxide and the balance of water essence.

Still more preferably, the anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 10.5% ginger extract, 2.5% kuh-seng root extract, 1.2% clerodendranthus spicatus extract, 0.5% cnidium fruit extract, 0.48% propylene glycol, 14.375% detergent, 1.5% cocamide MEA, 0.5% zinc PCA, 0.25% guar hydroxypropyltrimonium chloride, 0.15% polyquaternium-10, 0.48% zinc pyrithione, 1.5% dimethiconol, 0.5% zinc gluconate, 0.2% carbomer, 2% erythritol, 0.3% benzyl alcohol, 0.4% sodium benzoate, 0.002% hydroxyethyldiphosphonic acid, 0.0268% colorant, 0.01% sodium hydroxide and 0.2% essence, and the balance water.

Further, the weight ratio of the ginger extract to the sophora flavescens root extract to the clerodendranthus spicatus extract to the cnidium monnieri extract is 9-12:2-3:1-1.5: 0.5-1.

Preferably, the weight ratio of the ginger extract to the sophora flavescens ait root extract to the clerodendranthus spicatus extract to the cnidium monnieri fruit extract is 10-12:2-3:1-1.5: 0.5.

Further preferably, the weight ratio of the ginger extract, the sophora flavescens root extract, the clerodendranthus spicatus extract and the fructus cnidii extract is 10.5:2.5:1.2: 0.5.

Further, the weight ratio of the zinc pyrithione to the polydimethylsiloxane alcohol to the zinc gluconate is 0.2-0.6:1-1.5: 0.2-0.6.

Preferably, the weight ratio of the zinc pyrithione, the polydimethylsiloxane alcohol and the zinc gluconate is 0.2-0.5:1.5: 0.5.

Further preferably, the weight ratio of zinc pyrithione, dimethicone alcohol, and zinc gluconate is 0.48:1.5: 0.5.

Further, the colorant is one or more of CI16255, CI19140 and CI 42090; the detergent is one or more of sodium laureth sulfate, decyl glucoside, sodium trideceth sulfate and cocamidopropyl betaine. The cleanser is 8-12% of sodium laureth sulfate, 0.8-2% of decyl glucoside, 0.5-1.5% of sodium trideceth sulfate and 1-1.8% of cocamidopropyl betaine (the percentage of the cleanser to the total amount of the raw materials of the dandruff-removing oil-controlling shampoo).

Preferably, the colorants are 0.001-0.005% CI16255, 0.0001-0.0005% CI19140 and 0.0001-0.0002% CI42090 (the percentages being percentages of each colorant based on the total amount of the desquamation oil-control shampoo stock), and the cleansers are 10.5% sodium laureth sulfate, 1.5% decyl glucoside, 0.975% sodium trideceth sulfate and 1.4% cocamidopropyl betaine (the percentages being percentages of each cleanser based on the total amount of the desquamation oil-control shampoo stock).

Further preferably, the colorants are 0.00222% CI16255, 0.00036% CI19140 and 0.0001% CI42090 (the percentages being percentages of each colorant based on the total amount of the desquamation oil-control shampoo stock), and the cleansers are 10.5% sodium laureth sulfate, 1.5% decyl glucoside, 0.975% sodium trideceth sulfate and 1.4% cocamidopropyl betaine (the percentages being percentages of each cleanser based on the total amount of the desquamation oil-control shampoo stock).

Further, the extraction method of the ginger extract comprises the following steps: putting ginger into a decocting tool, adding 5 times of water by weight, decocting for 3 times, each time for 1h, filtering, mixing filtrates, concentrating under reduced pressure to obtain concentrated solution with relative density of 1.12, vacuum drying, pulverizing, and sieving with 80 mesh sieve to obtain the final product; the extraction method of the sophora flavescens root extract comprises the following steps: putting radix Sophorae Flavescentis into a decocting tool, adding 10 times of water, decocting for 2 times, each time for 1 hr, filtering, mixing filtrates, concentrating under reduced pressure to obtain concentrated solution with relative density of 1.25, vacuum drying, pulverizing, and sieving with 80 mesh sieve to obtain the final product; the extraction method of the clerodendranthus spicatus extract comprises the following steps: putting ginger into a decocting tool, adding 8 times of water by weight, decocting for 2 times, each time for 1h, filtering, mixing filtrates, concentrating under reduced pressure to obtain concentrated solution with relative density of 1.2, vacuum drying, pulverizing, and sieving with 80 mesh sieve to obtain the final product; the extraction method of the fructus cnidii extract comprises the following steps: putting ginger into a decocting tool, adding 5 times of water by weight, decocting for 2 times, each time for 1h, filtering, mixing filtrates, concentrating under reduced pressure to obtain concentrated solution with relative density of 1.3, vacuum drying, pulverizing, and sieving with 80 mesh sieve.

The invention also provides a preparation method of the anti-dandruff oil-control shampoo, which comprises the following steps:

(1) respectively dissolving the ginger extract and the sophora flavescens root extract in water to obtain an extracting solution A and an extracting solution B, dissolving the clerodendranthus spicatus extract in water and propylene glycol to obtain an extracting solution C, and mixing the extracting solution A, the extracting solution B, the extracting solution C and the fructus cnidii extract to obtain a mixed solution A;

(2) mixing a cleaning agent with water to obtain a mixed solution B; mixing zinc pyrithione and water to obtain a mixed solution C;

(3) heating water, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, CI16255, CI19140, CI42090, sodium hydroxide and essence, cooling, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, stirring uniformly, heating in stages, and cooling to obtain the anti-dandruff oil control shampoo.

Further, heating to 80-85 ℃ in the step (1); cooling to 30-35 ℃; the staged heating comprises the steps of heating to 40 ℃ for 3-5min for the first time, heating to 45 ℃ for 5-8min again, heating to 50-55 ℃ for the third time, and keeping for 3-5 min; and cooling to 25 ℃.

Preferably, the heating in step (1) is carried out to 82 ℃; cooling to 32 ℃; the staged heating comprises the steps of heating to 40 ℃ for 4min for the first time, heating to 45 ℃ for 6min again, and heating to 52 ℃ for 4min for the third time; and cooling to 25 ℃.

Further, the water compatible with the ginger extract, the sophora flavescens root extract and the clerodendranthus spicatus extract in the step (1) respectively accounts for 4-5%, 2-3% and 6-8% of the total amount of the shampoo raw material, the water mixed with the detergent in the step (2) accounts for 8-10% of the total amount of the shampoo raw material, and the water mixed with the zinc pyrithione accounts for 0.2-1% of the total amount of the shampoo raw material.

Preferably, the water soluble in the ginger extract, the sophora flavescens root extract and the clerodendranthus spicatus extract in step (1) accounts for 4.5%, 2.5% and 7.2% of the total amount of the shampoo raw material, respectively, the water mixed with the detergent in step (2) accounts for 9.125% of the total amount of the shampoo raw material, and the water mixed with zinc pyrithione accounts for 0.52% of the total amount of the shampoo raw material.

The technical effects obtained by the invention are as follows:

1. the preparation method is simple and convenient, and the shampoo prepared by reasonably proportioning the ginger extract, the sophora flavescens root extract, the clerodendranthus spicatus extract and the fructus cnidii extract has good dandruff removing and oil control capabilities;

2. the shampoo in the application has high safety, cannot generate stimulation and sensitization, and is good in public experience.

Detailed Description

It should be noted that the raw materials in the present invention are all common commercially available products, and therefore, the sources thereof are not particularly limited, and among them, ginger extract, sophora flavescens root extract, clerodendranthus spicatus extract, and cnidium monnieri fruit extract are prepared in the manner described in the specification.

Example 1

An anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 9% ginger extract, 1.8% sophora flavescens root extract, 0.8% clerodendrum spicatum extract, 0.2% cnidium fruit extract, 0.2% propylene glycol, 8% sodium laureth sulfate, 0.8% decyl glucoside, 0.5% sodium trideceth sulfate, 1% cocamidopropyl betaine, 0.8% cocamide MEA, 0.2% zinc PCA, 0.1% guar hydroxypropyltrimonium chloride, 0.05% polyquaternium-10, 0.2% zinc pyrithione, 1% dimethiconol, 0.2% zinc gluconate, 0.1% carbomer, 1% erythritol, 0.1% benzyl alcohol, 0.2% sodium benzoate, 0.001% hydroxyethyl diphosphate, 0.001% CI16255, 0.0001% CI19140, 0.0001% CI42090, 0.005% sodium hydroxide and 0.1% essence, the balance being water.

The preparation method of the anti-dandruff oil-control shampoo comprises the following steps:

(3) heating water to 80 ℃, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, CI16255, CI19140, CI42090, sodium hydroxide and essence, cooling to 30 ℃, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, uniformly stirring, primarily heating to 40 ℃ for 3min, heating to 45 ℃ for 5min, thirdly heating to 50 ℃ for 3min, and cooling to 25 ℃ to obtain the anti-dandruff oil-control shampoo.

Wherein, the water which is compatible with the ginger extract, the sophora flavescens root extract and the clerodendranthus spicatus extract in the step (1) respectively accounts for 4 percent, 2 percent and 6 percent of the total amount of the raw materials of the shampoo, the water which is mixed with the cleaning agent in the step (2) accounts for 8 percent of the total amount of the raw materials of the shampoo, and the water which is mixed with the zinc pyrithione accounts for 0.2 percent of the total amount of the raw materials of the shampoo.

Example 2

An anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 12% ginger extract, 3% sophora flavescens root extract, 1.5% clerodendrum spicatum extract, 1% cnidium fruit extract, 0.8% propylene glycol, 12% sodium laureth sulfate, 2% decyl glucoside, 1.5% sodium trideceth sulfate, 1.8% cocamidopropyl betaine, 2% cocamide MEA, 0.8% zinc PCA, 0.5% guar hydroxypropyltrimonium chloride, 0.3% polyquaternium-10, 0.6% zinc pyrithione, 1.8% dimethiconol, 0.6% zinc gluconate, 0.5% carbomer, 3% erythritol, 0.5% benzyl alcohol, 0.6% sodium benzoate, 0.005% hydroxyethyl diphosphate, 0.005% CI16255, 0.0005% CI19140, 0.0002% CI42090, 0.02% sodium hydroxide, 0.4% essence, and the balance water.

(3) heating water to 85 ℃, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, CI16255, CI19140, CI42090, sodium hydroxide and essence, cooling to 35 ℃, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, uniformly stirring, primarily heating to 40 ℃ for 5min, heating to 45 ℃ for 8min again, heating to 50 ℃ for 5min for the third time, and cooling to 25 ℃ to obtain the anti-dandruff oil control shampoo.

Wherein, the water which is compatible with the ginger extract, the sophora flavescens root extract and the clerodendranthus spicatus extract in the step (1) respectively accounts for 5 percent, 3 percent and 8 percent of the total amount of the shampoo raw material, the water which is mixed with the cleaning agent in the step (2) accounts for 10 percent of the total amount of the shampoo raw material, and the water which is mixed with the zinc pyrithione accounts for 1 percent of the total amount of the shampoo raw material.

Example 3

An anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 10.5% ginger extract, 2.5% sophora flavescens root extract, 1.2% clerodendrum spicatum extract, 0.5% cnidium fruit extract, 0.48% propylene glycol, 10.5% sodium laureth sulfate, 1.5% decyl glucoside, 0.975% sodium trideceth sulfate, 1.4% cocamidopropyl betaine, 1.5% cocamide MEA, 0.5% zinc PCA, 0.25% guar hydroxypropyltrimonium chloride, 0.15% polyquaternium-10, 0.48% zinc pyrithione, 1.5% dimethiconol, 0.5% zinc gluconate, 0.2% carbomer, 2% erythritol, 0.3% benzyl alcohol, 0.4% sodium benzoate, 0.002% ethylene glycol diphosphate, 0.00222% CI16255, 0.00036% CI19140, 0.0001% CI42090, 0.01% sodium hydroxide and 0.2% essence, the balance being water.

(3) heating water to 82 ℃, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, CI16255, CI19140, CI42090, sodium hydroxide and essence, cooling to 32 ℃, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, uniformly stirring, primarily heating to 40 ℃ for 4min, heating to 45 ℃ for 6min, thirdly heating to 50 ℃ for 4min, and cooling to 25 ℃ to obtain the anti-dandruff oil-control shampoo.

Wherein, the water which is compatible with the ginger extract, the sophora flavescens root extract and the clerodendranthus spicatus extract in the step (1) respectively accounts for 4.5 percent, 2.5 percent and 7.2 percent of the total amount of the shampoo raw material, the water which is mixed with the cleaning agent in the step (2) accounts for 9.125 percent of the total amount of the shampoo raw material, and the water which is mixed with the zinc pyrithione accounts for 0.52 percent of the total amount of the shampoo raw material.

Example 4

An anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 10% ginger extract, 2% sophora flavescens root extract, 1% clerodendranthus spicatus extract, 0.3% cnidium fruit extract, 0.3% propylene glycol, 9% sodium laureth sulfate, 1.2% decyl glucoside, 0.8% sodium trideceth sulfate, 1.2% cocamidopropyl betaine, 1% cocamide MEA, 0.3% zinc PCA, 0.2% guar hydroxypropyltrimonium chloride, 0.1% polyquaternium-10, 0.3% zinc pyrithione, 1.1% dimethiconol, 0.3% zinc gluconate, 0.15% carbomer, 1.8% erythritol, 0.2% benzyl alcohol, 0.3% sodium benzoate, 0.0015% hydroxyethyldiphosphonic acid, 0.002% CI 42055, 0.0002% CI19140, 0.0001% CI42090, 0.008% sodium hydroxide and 0.15% essence, the balance being water.

(3) heating water to 81 ℃, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, CI16255, CI19140, CI42090, sodium hydroxide and essence, cooling to 31 ℃, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, uniformly stirring, primarily heating to 40 ℃ for 3min, secondarily heating to 45 ℃ for 5min, thirdly heating to 50 ℃ for 5min, and cooling to 25 ℃ to obtain the anti-dandruff oil control shampoo.

Example 5

An anti-dandruff oil-control shampoo comprises the following raw materials in percentage by weight: 11% ginger extract, 2.8% sophora flavescens root extract, 1.4% clerodendrum spicatum extract, 0.8% cnidium fruit extract, 0.5% propylene glycol, 11% sodium laureth sulfate, 1.8% decyl glucoside, 1.2% sodium trideceth sulfate, 1.5% cocamidopropyl betaine, 1.8% cocamide MEA, 0.6% zinc PCA, 0.3% guar hydroxypropyltrimonium chloride, 0.2% polyquaternium-10, 0.5% zinc pyrithione, 1.6% dimethiconol, 0.55% zinc gluconate, 0.25% carbomer, 2.2% erythritol, 0.4% benzyl alcohol, 0.5% sodium benzoate, 0.003% ethylene glycol diphosphate, 0.003% CI16255, 0.0004% CI19140, 0.00015% CI42090, 0.015% sodium hydroxide and 0.3% essence, the balance being water.

(3) heating water to 83 ℃, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, CI16255, CI19140, CI42090, sodium hydroxide and essence, cooling to 33 ℃, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, uniformly stirring, primarily heating to 40 ℃ for 3min, secondarily heating to 45 ℃ for 5min, thirdly heating to 50 ℃ for 5min, and cooling to 25 ℃ to obtain the anti-dandruff oil control shampoo.

Comparative example 1

The difference from the example 3 is only that the raw materials comprise the following components in percentage by weight: 8% ginger extract, 4% sophora flavescens root extract, 0.5% clerodendranthus spicatus extract, 1.5% cnidium fruit extract, 0.1% propylene glycol, 13% sodium laureth sulfate, 0.5% decyl glucoside, 1.8% sodium trideceth sulfate, 0.8% cocamidopropyl betaine, 0.5% cocamide MEA, 1% zinc PCA, 0.05% guar hydroxypropyltrimonium chloride, 0.4% polyquaternium-10, 0.1% zinc pyrithione, 2% dimethiconol, 0.1% zinc gluconate, 0.6% carbomer, 0.5% erythritol, 0.6% benzyl alcohol, 0.1% sodium benzoate, 0.008% ethylene glycol diphosphate, 0.0005% CI16255, 0.0006% CI19140, 0.0001% CI42090, 0.03% sodium hydroxide and 0.05% essence, the balance being water.

Comparative example 2

The difference from the example 3 is only that the raw materials comprise the following components in percentage by weight: 14% ginger extract, 1.5% sophora flavescens root extract, 2% clerodendranthus spicatus extract, 0.1% cnidium fruit extract, 1% propylene glycol, 7% sodium laureth sulfate, 2.2% decyl glucoside, 0.4% sodium trideceth sulfate, 2% cocamidopropyl betaine, 3% cocamide MEA, 0.1% zinc PCA, 0.6% guar hydroxypropyltrimonium chloride, 0.03% polyquaternium-10, 0.8% zinc pyrithione, 0.5% dimethiconol, 0.8% zinc gluconate, 0.05% carbomer, 4% erythritol, 0.05% benzyl alcohol, 0.8% sodium benzoate, 0.001% hydroxyethyl diphosphate, 0.006% CI16255, 0.00005% CI19140, 0.0003% CI42090, 0.003% sodium hydroxide, and 0.5% of essence, the balance being water.

Comparative example 3

The only difference from example 3 is that the weight ratio of ginger extract, sophora flavescens root extract, clerodendranthus spicatus extract and cnidium monnieri fruit extract is 8:4:0.8:1.2 (the total weight of ginger extract, sophora flavescens root extract, clerodendranthus spicatus extract and cnidium monnieri fruit extract is identical to example 3).

Comparative example 4

The only difference from example 3 is that the weight ratio of zinc pyrithione, dimethicone alcohol and zinc gluconate is 0.8:0.5:0.8 (the median weight of zinc pyrithione, dimethicone alcohol and zinc gluconate is consistent with example 3).

Comparative example 5

The only difference from example 3 is that in the preparation method, the heating to 75 ℃ is carried out in step (1); cooling to 40 ℃; heating to 40 deg.C for 2min, heating to 45 deg.C for 10min, and heating to 60 deg.C for 6 min; cooled to 25 ℃.

Comparative example 6

The only difference from example 3 is that the staged temperature increase was replaced by a direct temperature increase to 52 ℃ for 14 min.

Comparative example 7

The anti-dandruff oil-control shampoo disclosed in patent CN106236659A in example 1.

Skin irritation and allergy test

Test animals: 96 young guinea pigs weighing about 200g were obtained.

The test method comprises dividing guinea pigs into 12 groups randomly, shaving the backs of the guinea pigs (shaving area is 3 × 3cm), applying the shampoo of examples 1-5 or comparative examples 1-7 on hair-removed areas of the guinea pigs after 24h, washing the shampoo with warm water after 30min, observing whether the skin of the guinea pigs has erythema or edema after washing the shampoo for 1h and 24h, judging the stimulation intensity according to the scoring standard and the intensity standard, and observing whether the skin has allergy or not at the same time, and observing whether the skin has allergy or not after 24h (i.e. symptoms such as uneasiness, nasal scratching, sneezing, dyspnea, hair erection, incontinence of urine and feces, spasmodic jump or death), and counting the observation results to table 2.

TABLE 1 criteria

TABLE 2

Note: the data in the table are mean values.

As can be seen from table 2, the shampoos of examples 1 to 5 and comparative examples 3 to 6 were non-irritating and sensitizing to guinea pigs, the guinea pigs of comparative example 1 exhibited moderate irritation characteristics, and at the same time, slight restlessness, sneezing or hair-lifting, and the guinea pigs of comparative example 2 and comparative example 7 exhibited slight irritation, but no allergy occurred.

Second, the oil control effect test

220 volunteers with more scurf and oily hair were selected and aged 15-60 years, and the volunteers were randomly divided into 11 groups of 20 persons each, and the shampoos of examples 1-5 and comparative examples 2-7 were used, respectively, to perform hair washing once a day in the morning, and the oily condition of hair was observed in the morning the next day after one week of continuous hair washing, and the evaluation criteria of the effects are shown in Table 3, and the number of persons was counted in Table 4. At the same time, the volunteers were investigated for their sensory experience with respect to smell, sight and feel of the shampoo, and the scores were counted in table 4.

TABLE 3 evaluation criteria for Effect

Effect	Standard of merit
		Show effect	The hair has no greasy, dandruff, dryness, and greasy feeling
Is effective	The hair oiliness is improved compared with that before the test, the greasy feeling is not obvious, and the dandruff is less
		Invalidation	The hair oiliness and dandruff are not changed any more than before the test

TABLE 4

Note: the scores in the table are all average scores.

As can be seen from table 4, the shampoo in examples 1 to 5 has good anti-dandruff and oil-control effects, the total effective rate is more than 90%, and the experience sensory score is more than 9%, wherein the shampoo in example 3 has the best effect, the effective rate of anti-dandruff and oil-control is 100%, and the experience sensory score is 9.7%. Compared with the shampoo prepared in the embodiment 3, the shampoo prepared in the comparative examples 2-7 has poor effect, so that the raw material proportion and the preparation method of the shampoo greatly influence the efficacy of the shampoo, and the shampoo has excellent anti-dandruff and oil control effects and good public experience.

Finally, it should be noted that the above-mentioned contents are only used for illustrating the technical solutions of the present invention, and not for limiting the protection scope of the present invention, and that the simple modifications or equivalent substitutions of the technical solutions of the present invention by those of ordinary skill in the art can be made without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. An anti-dandruff oil-control shampoo is characterized in that: the raw materials comprise the following components in percentage by weight: 10-11% of ginger extract, 2-2.8% of sophora flavescens root extract, 1-1.4% of clerodendranthus spicatus extract, 0.3-0.8% of cnidium monnieri extract, 0.3-0.5% of propylene glycol, 12.2-15.5% of cleaning agent, 1-1.8% of cocamide MEA, 0.3-0.6% of PCA zinc, 0.2-0.3% of guar hydroxypropyl trimonium chloride, 0.1-0.2% of polyquaternium-10, 0.3-0.5% of zinc pyrithione, 1.1-1.6% of dimethiconol, 0.3-0.55% of zinc gluconate, 0.15-0.25% of carbomer, 1.8-2.2% of erythritol, 0.2-0.4% of benzyl alcohol, 0.3-0.5% of benzene, 0.0015-0.003% of hydroxyethyl diphosphate, 0.0023-0.00355% of sodium hydroxide, 0.015-0.015% of sodium hydroxide and the balance of water essence; the weight ratio of the ginger extract to the sophora flavescens root extract to the clerodendranthus spicatus extract to the fructus cnidii extract is 9-12:2-3:1-1.5: 0.5-1; the cleanser is 8-12% of sodium laureth sulfate, 0.8-2% of decyl glucoside, 0.5-1.5% of sodium trideceth sulfate and 1-1.8% of cocamidopropyl betaine.

2. The anti-dandruff oil-control shampoo according to claim 1, characterized in that: the weight ratio of the ginger extract to the sophora flavescens root extract to the clerodendranthus spicatus extract to the fructus cnidii extract is 10-12:2-3:1-1.5: 0.5.

3. The anti-dandruff oil-control shampoo according to claim 1, characterized in that: the colorant is one or more of CI16255, CI19140 and CI 42090.

4. A process for the preparation of an anti-dandruff, oil-control shampoo according to any of claims 1 to 3, characterized in that: the method comprises the following steps:

(3) heating water, adding carbomer, cocamide MEA, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternium-10, dimethiconol, zinc gluconate, PCA zinc salt, erythritol, benzyl alcohol, sodium benzoate, hydroxyethyl diphosphate, a colorant, sodium hydroxide and essence, cooling, adding the mixed solution A in the step (1), the mixed solution B in the step (2) and the mixed solution C, uniformly stirring, heating by stages, and cooling to obtain the anti-dandruff oil control shampoo.

5. The method of claim 4, wherein: heating to 80-85 ℃ in the step (3); cooling to 30-35 ℃; the staged heating comprises the steps of heating to 40 ℃ for 3-5min for the first time, heating to 45 ℃ for 5-8min again, heating to 50-55 ℃ for the third time, and keeping for 3-5 min; and cooling to 25 ℃.