CN110693777A - Anti-hair loss and dandruff removing shampoo and preparation method thereof - Google Patents

Anti-hair loss and dandruff removing shampoo and preparation method thereof Download PDF

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CN110693777A
CN110693777A CN201911021308.3A CN201911021308A CN110693777A CN 110693777 A CN110693777 A CN 110693777A CN 201911021308 A CN201911021308 A CN 201911021308A CN 110693777 A CN110693777 A CN 110693777A
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parts
extract
hair loss
shampoo
dandruff
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李双峰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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Abstract

The invention provides an anti-hair loss and dandruff removing shampoo and a preparation method thereof, and belongs to the field of cosmetics. The shampoo provided by the invention comprises the following components in percentage by mass: 20-25% of a surfactant, 25-30% of a natural extract, 10-15% of an auxiliary agent and the balance of water; the natural extracts include centella asiatica extract, rice fermentation product filtrate, scutellaria baicalensis root extract, and tea leaf extract. The natural extract in the shampoo cream provided by the invention is compounded by the centella extract, the rice fermentation product filtrate, the scutellaria root extract and the tea extract, has a synergistic effect, has an obvious anti-alopecia effect, obviously enhances the sterilization capability, can reduce excessive sebum secretion of scalp, inhibits the reproduction of bacteria, fundamentally blocks an external channel generated by dandruff, and thus effectively removes dandruff and relieves itching.

Description

Anti-hair loss and dandruff removing shampoo and preparation method thereof
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to a shampoo capable of preventing alopecia and removing dandruff and a preparation method thereof.
Background
With the acceleration of life pace, the increase of life pressure and the increasing of environmental pollution, the incidence of hair diseases such as alopecia and withered and yellow hair of modern people is higher and higher. More than 3 hundred million typical alopecia patients and premature graying hair patients exist in adult people in China. Alopecia and poliosis are pathological phenomena, which need to be treated as early as possible, and the number of alopecia people is increased at a rate of about 15% per year, and the alopecia people tend to be younger. The alopecia not only seriously affects normal work and life of people, but also seriously destroys the psychological health of patients, and causes different influences on work, life, social activities and the like.
Disclosure of Invention
In view of the above, the invention aims to provide a shampoo for preventing alopecia and removing dandruff and a preparation method thereof. The shampoo provided by the invention has a remarkable anti-hair loss effect.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides an anti-hair loss and dandruff removing shampoo, which comprises the following components in percentage by mass:
20-25% of a surfactant, 25-30% of a natural extract, 10-15% of an auxiliary agent and the balance of water;
the natural extracts include centella asiatica extract, rice fermentation product filtrate, scutellaria baicalensis root extract, and tea leaf extract.
Preferably, the natural extract consists of the following components in parts by mass: 3-10 parts of a centella asiatica extract, 10-25 parts of a rice fermentation product filtrate, 3-15 parts of a scutellaria baicalensis root extract and 8-20 parts of a tea leaf extract.
Preferably, the natural extract consists of the following components in parts by mass: 5-8 parts of a centella asiatica extract, 15-20 parts of a rice fermentation product filtrate, 5-10 parts of a scutellaria baicalensis root extract and 10-15 parts of a tea leaf extract.
Preferably, the concentration of centella asiatica extract, scutellaria baicalensis root extract and tea extract is independently 0.8-1.5 g/mL.
Preferably, the surfactant is composed of the following components in parts by mass: 5-20 parts of ammonium laureth sulfate, 5-20 parts of sodium laureth sulfate, 5-10 parts of cocamide DEA, 5-10 parts of cocamide MEA and 2-5 parts of cocamidopropyl betaine.
Preferably, the surfactant is composed of the following components in parts by mass: 10-15 parts of ammonium laureth sulfate, 10-15 parts of sodium laureth sulfate, 7-8 parts of cocamide DEA, 7-8 parts of cocamide MEA and 3-4 parts of cocamidopropyl betaine.
Preferably, the auxiliary agent consists of the following components in parts by mass: 0.8-2 parts of bacteriostatic agent, 0.1-0.2 part of sodium chloride, 0.1-0.2 part of magnesium nitrate, 0.5-0.8 part of polyquaternium-10, 0.5-0.8 part of DMDM hydantoin, 0.3-0.5 part of allantoin, 0.3-0.5 part of zinc pyrithione, 1-2 parts of essence, 0.5-0.8 part of guar gum hydroxypropyl trimethyl ammonium chloride and 0.5-0.8 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer.
Preferably, the bacteriostatic agent comprises 0.4-1 part of methyl chloroisothiazolinone and 0.4-1 part of methyl isothiazolinone.
The invention also provides a preparation method of the anti-hair loss and dandruff removing shampoo in the technical scheme, which comprises the following steps:
mixing the natural extract, the surfactant, the auxiliary agent and water to obtain the anti-hair loss and dandruff removing shampoo.
The invention provides an anti-hair loss and dandruff removing shampoo, which comprises the following components in percentage by mass: 20-25% of a surfactant, 25-30% of a natural extract, 10-15% of an auxiliary agent and the balance of water; the natural extracts include centella asiatica extract, rice fermentation product filtrate, scutellaria baicalensis root extract, and tea leaf extract. The asiaticoside and the madecassoside are main components of the asiatic pennywort herb extract, have the functions of sterilization and inflammation diminishing, can effectively promote blood circulation, inhibit bacteria from breeding on the surface of the scalp and eliminate scalp inflammation; the rice fermentation product filtrate has high permeability to scalp, can maintain the softness and moisture of scalp cells, promote scalp metabolism, and inhibit scalp inflammation; the scutellaria root extract is rich in baicalin, has good effects of resisting inflammation and relieving skin, has a certain oil control effect, can reduce excessive sebum secretion of scalp and inhibit bacterial reproduction; the tea extract has effects of astringing skin, keeping moisture, inhibiting bacteria and resisting inflammation, and can effectively inhibit bacteria from breeding on scalp surface and eliminate scalp inflammation. The natural extract in the shampoo cream provided by the invention is compounded by the centella extract, the rice fermentation product filtrate, the scutellaria root extract and the tea extract, has a synergistic effect, has an obvious anti-alopecia effect, obviously enhances the sterilization capability, can reduce excessive sebum secretion of scalp, inhibits the reproduction of bacteria, fundamentally blocks an external channel generated by dandruff, and thus effectively removes dandruff and relieves itching. The shampoo provided by the invention can continuously improve symptoms such as alopecia, dandruff removal, oil removal and the like. Meanwhile, the shampoo provided by the invention has the characteristics of fragrant smell, and smooth and unharmful hair after being washed by moisture.
Detailed Description
The invention provides an anti-hair loss and dandruff removing shampoo, which comprises the following components in percentage by mass:
20-25% of a surfactant, 25-30% of a natural extract, 10-15% of an auxiliary agent and the balance of water.
In the present invention, the starting materials used are all commercially available products which are conventional in the art, and are not specifically described.
The anti-hair loss and dandruff removing shampoo provided by the invention comprises 25-30% of natural extract by mass, more preferably 27-29% of natural extract by mass, and even more preferably 28% of natural extract by mass. In the present invention, the natural extracts include centella asiatica extract, rice fermentation product filtrate, scutellaria baicalensis root extract, and tea leaf extract; the natural extract is preferably composed of the following components in parts by mass: 3-10 parts of a centella asiatica extract, 10-25 parts of a rice fermentation product filtrate, 3-15 parts of a scutellaria baicalensis root extract and 8-20 parts of a tea extract, and further preferably 5-8 parts of a centella asiatica extract, 15-20 parts of a rice fermentation product filtrate, 5-10 parts of a scutellaria baicalensis root extract and 10-15 parts of a tea extract; the concentration of centella asiatica extract, scutellaria baicalensis root extract and tea extract is preferably 0.8-1.5 g/mL, and more preferably 1-1.2 g/mL. The asiaticoside and the madecassoside are used as main components of the asiatic pennywort herb extract, have the functions of sterilization and inflammation diminishing, can effectively promote blood circulation, inhibit bacteria from breeding on the surface of the scalp and eliminate scalp inflammation; the rice fermentation product filtrate has high permeability to scalp, can maintain the softness and moisture of scalp cells, promote scalp metabolism, and inhibit scalp inflammation; the scutellaria root extract is rich in baicalin, has good effects of resisting inflammation and relieving skin, has a certain oil control effect, can reduce excessive sebum secretion of scalp and inhibit bacterial reproduction; the tea extract has effects of astringing skin, keeping moisture, inhibiting bacteria and resisting inflammation, and can effectively inhibit bacteria from breeding on scalp surface and eliminate scalp inflammation. The natural extract in the shampoo paste provided by the invention is compounded by the centella extract, the rice fermentation product filtrate, the scutellaria root extract and the tea extract with specific component contents, has a synergistic effect, has a remarkable anti-alopecia effect, remarkably enhances the sterilization capability, can reduce excessive sebum secretion of scalp, inhibits the reproduction of bacteria, fundamentally blocks an external channel generated by dandruff, and thus effectively removes dandruff and relieves itching. The source of the natural extract is not particularly limited in the present invention, and the natural extract can be prepared by a method well known to those skilled in the art or a commercially available product conventionally used in the art.
The anti-hair loss and dandruff removing shampoo provided by the invention comprises 20-25% of a surfactant by mass, preferably 22-24% of the surfactant by mass, and more preferably 23% of the surfactant by mass. In the present invention, the surfactant is preferably composed of the following components in parts by mass: 5-20 parts of ammonium laureth sulfate, 5-20 parts of sodium laureth sulfate, 5-10 parts of DEA cocoamide, 5-10 parts of MEA cocoamide and 2-5 parts of cocamidopropyl betaine, and further preferably 10-15 parts of ammonium laureth sulfate, 10-15 parts of sodium laureth sulfate, 7-8 parts of DEA cocoamide, 7-8 parts of MEA cocoamide and 3-4 parts of cocamidopropyl betaine.
The anti-hair loss and dandruff removing shampoo provided by the invention comprises 10-15% of an auxiliary agent by mass, more preferably 12-14% of the auxiliary agent by mass, and even more preferably 13% of the auxiliary agent by mass. In the invention, the auxiliary agent preferably comprises the following components in parts by mass: 0.8-2 parts of bacteriostatic agent, 0.1-0.2 part of sodium chloride, 0.1-0.2 part of magnesium nitrate, 0.5-0.8 part of polyquaternium-10, 0.5-0.8 part of DMDM hydantoin, 0.3-0.5 part of allantoin, 0.3-0.5 part of zinc pyrithione, 1-2 parts of essence, 0.5-0.8 part of guar gum hydroxypropyl trimethyl ammonium chloride and 0.5-0.8 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, further preferably 1-1.5 parts of bacteriostatic agent, 0.12-0.18 part of sodium chloride, 0.12-0.18 part of magnesium nitrate, 0.6-0.7 part of polyquaternium-10, 0.6-0.7 part of DMDM hydantoin, 0.35-0.45 part of allantoin, 0.35-0.45 part of zinc pyrithione, 1.2-1.8 parts of essence, 0.6-0.7 part of guar gum hydroxypropyl trimethyl ammonium chloride and 0.6-0.7 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer. In the invention, the bacteriostatic agent preferably comprises 0.4-1 part of methylchloroisothiazolinone and 0.4-1 part of methylisothiazolinone, and further preferably 0.5-0.8 part of methylchloroisothiazolinone and 0.5-0.8 part of methylisothiazolinone. The invention has no special limitation on the types of the essences, and can adopt the conventional essence types in the field.
In the present invention, the water is preferably deionized water.
The invention also provides a preparation method of the anti-hair loss and dandruff removing shampoo in the technical scheme, which comprises the following steps:
mixing the natural extract, the surfactant, the auxiliary agent and water to obtain the anti-hair loss and dandruff removing shampoo.
In the embodiment of the present invention, the mixing order is preferably that the surfactant, water, sodium chloride, magnesium nitrate, polyquaternium-10, DMDM hydantoin, allantoin, zinc pyrithione, guar hydroxypropyltrimonium chloride and acrylic acid/C10-30 alkanol acrylate cross-linked polymer are first mixed, then sequentially mixed with the natural extract for the second time, and finally mixed with the bacteriostatic agent and the essence for the third time. In the present invention, the order of the first mixing is not particularly limited, and any mixing order may be adopted. In the present invention, the temperature of the first mixing is preferably 70 to 85 ℃. The time and the speed of the first mixing are not specially limited, and the raw materials can be uniformly mixed. The operation mode of the first mixing is not particularly limited in the invention, and a conventional mixing operation mode in the field can be adopted. In the present invention, the temperature of the second mixing is preferably 45 to 55 ℃. The time and the speed of the second mixing are not specially limited, and the raw materials can be uniformly mixed. The operation mode of the second mixing and the third mixing is not particularly limited in the present invention, and a conventional mixing mode in the art can be adopted.
After the completion of the mixing, the present invention preferably adjusts the pH of the resulting mixed product. In the invention, the pH value after adjustment is preferably 5.5-7.5. The reagent for adjusting the pH value is not particularly limited in the invention, and the reagent for adjusting the pH value can be adjusted by adopting the conventional reagent in the field. The present invention is not limited to the above-mentioned adjustment method, and the adjustment method known to those skilled in the art can be adopted.
The anti-alopecia and anti-dandruff shampoo and the preparation method thereof provided by the present invention will be described in detail with reference to the following examples, but they should not be construed as limiting the scope of the present invention.
Example 1
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
20% of surfactant, 25% of natural extract, 10% of auxiliary agent and 45% of water;
weighing 3 parts of 1.5g/mL asiatic pennywort herb extract, 10 parts of rice fermentation product filtrate, 3 parts of 1.5g/mL baical skullcap root extract and 8 parts of 1.5g/mL tea extract according to the mass parts, and mixing to obtain a natural extract mixture;
weighing 5 parts of ammonium laureth sulfate, 5 parts of sodium laureth sulfate, 5 parts of cocamide DEA, 5 parts of cocamide MEA and 2 parts of cocamidopropyl betaine according to parts by weight, and mixing to obtain a surfactant mixture;
weighing 0.8 part of bacteriostatic agent, 0.1 part of sodium chloride, 0.1 part of magnesium nitrate, 0.5 part of polyquaternium-10, 0.5 part of DMDM hydantoin, 0.3 part of allantoin, 0.3 part of zinc pyrithione, 1 part of essence, 0.5 part of guar hydroxypropyl trimethyl ammonium chloride and 0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 0.4 part of methyl chloro isothiazolinone and 0.4 part of methyl isothiazolinone.
Mixing the surfactant mixture, sodium chloride, magnesium nitrate, polyquaternium-10, DMDM hydantoin, allantoin, zinc pyrithione, guar gum hydroxypropyl trimethyl ammonium chloride, acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer and water in parts by weight at 70 ℃, mixing the mixture with the natural extract mixture at 45 ℃, mixing the mixture with a bacteriostatic agent and a essence, and adjusting the pH value to 5.5 to obtain the anti-hair loss and dandruff removing shampoo.
Example 2
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
25% of surfactant, 30% of natural extract, 15% of auxiliary agent and 30% of water;
weighing 10 parts of centella asiatica extract 0.8g/mL, 25 parts of rice fermentation product filtrate, 15 parts of scutellaria baicalensis root extract 0.8g/mL and 20 parts of tea extract 0.8g/mL according to parts by weight, and mixing to obtain a natural extract mixture;
weighing 20 parts of ammonium laureth sulfate, 20 parts of sodium laureth sulfate, 10 parts of cocamide DEA, 10 parts of cocamide MEA and 5 parts of cocamidopropyl betaine according to parts by mass, and mixing to obtain a surfactant mixture;
weighing 2 parts of bacteriostatic agent, 0.2 part of sodium chloride, 0.2 part of magnesium nitrate, 0.8 part of polyquaternium-10, 0.8 part of DMDM hydantoin, 0.5 part of allantoin, 0.5 part of zinc pyrithione, 2 parts of essence, 0.8 part of guar hydroxypropyl trimethyl ammonium chloride and 0.8 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 1 part of methylchloroisothiazolinone and 1 part of methylisothiazolinone.
The preparation method of the shampoo for preventing alopecia and removing dandruff is the same as that of the example 1.
Example 3
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
23% of surfactant, 28% of natural extract, 13% of auxiliary agent and 36% of water;
weighing 6 parts of 1.1g/mL asiatic pennywort herb extract, 17 parts of rice fermentation product filtrate, 8 parts of 1.1g/mL baical skullcap root extract and 12 parts of 1.1g/mL tea extract according to the mass parts, and mixing to obtain a natural extract mixture;
weighing 12 parts of ammonium laureth sulfate, 12 parts of sodium laureth sulfate, 8 parts of cocamide DEA, 8 parts of cocamide MEA and 3 parts of cocamidopropyl betaine according to parts by mass, and mixing to obtain a surfactant mixture;
weighing 1.5 parts of bacteriostatic agent, 0.15 part of sodium chloride, 0.15 part of magnesium nitrate, 0.7 part of polyquaternium-10, 0.7 part of DMDM hydantoin, 0.4 part of allantoin, 0.4 part of zinc pyrithione, 1.5 parts of essence, 0.7 part of guar gum hydroxypropyl trimethyl ammonium chloride and 0.7 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 1.2 parts of methylchloroisothiazolinone and 1.3 parts of methylisothiazolinone.
The preparation method of the shampoo for preventing alopecia and removing dandruff is the same as that of the example 1.
Comparative example 1
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
20% of surfactant, 25% of natural extract, 10% of auxiliary agent and 45% of water;
weighing 3 parts of 1.5g/mL centella asiatica extract according to the mass part;
weighing 5 parts of ammonium laureth sulfate, 5 parts of sodium laureth sulfate, 5 parts of cocamide DEA, 5 parts of cocamide MEA and 2 parts of cocamidopropyl betaine according to parts by weight, and mixing to obtain a surfactant mixture;
weighing 0.8 part of bacteriostatic agent, 0.1 part of sodium chloride, 0.1 part of magnesium nitrate, 0.5 part of polyquaternium-10, 0.5 part of DMDM hydantoin, 0.3 part of allantoin, 0.3 part of zinc pyrithione, 1 part of essence, 0.5 part of guar hydroxypropyl trimethyl ammonium chloride and 0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 0.4 part of methyl chloro isothiazolinone and 0.4 part of methyl isothiazolinone.
The preparation method of the shampoo for preventing alopecia and removing dandruff is the same as that of the example 1.
Comparative example 2
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
20% of surfactant, 25% of natural extract, 10% of auxiliary agent and 45% of water;
weighing 10 parts of rice fermentation product filtrate according to parts by weight;
weighing 5 parts of ammonium laureth sulfate, 5 parts of sodium laureth sulfate, 5 parts of cocamide DEA, 5 parts of cocamide MEA and 2 parts of cocamidopropyl betaine according to parts by weight, and mixing to obtain a surfactant mixture;
weighing 0.8 part of bacteriostatic agent, 0.1 part of sodium chloride, 0.1 part of magnesium nitrate, 0.5 part of polyquaternium-10, 0.5 part of DMDM hydantoin, 0.3 part of allantoin, 0.3 part of zinc pyrithione, 1 part of essence, 0.5 part of guar hydroxypropyl trimethyl ammonium chloride and 0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 0.4 part of methyl chloro isothiazolinone and 0.4 part of methyl isothiazolinone.
The preparation method of the shampoo for preventing alopecia and removing dandruff is the same as that of the example 1.
Comparative example 3
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
20% of surfactant, 25% of natural extract, 10% of auxiliary agent and 45% of water;
weighing 3 parts of 1.5g/mL scutellaria baicalensis root extract according to the mass part;
weighing 5 parts of ammonium laureth sulfate, 5 parts of sodium laureth sulfate, 5 parts of cocamide DEA, 5 parts of cocamide MEA and 2 parts of cocamidopropyl betaine according to parts by weight, and mixing to obtain a surfactant mixture;
weighing 0.8 part of bacteriostatic agent, 0.1 part of sodium chloride, 0.1 part of magnesium nitrate, 0.5 part of polyquaternium-10, 0.5 part of DMDM hydantoin, 0.3 part of allantoin, 0.3 part of zinc pyrithione, 1 part of essence, 0.5 part of guar hydroxypropyl trimethyl ammonium chloride and 0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 0.4 part of methyl chloro isothiazolinone and 0.4 part of methyl isothiazolinone.
The preparation method of the shampoo for preventing alopecia and removing dandruff is the same as that of the example 1.
Comparative example 4
The embodiment provides an anti-hair loss and dandruff removing shampoo which comprises the following components in percentage by mass:
20% of surfactant, 25% of natural extract, 10% of auxiliary agent and 45% of water;
weighing 8 parts of 1.5g/mL tea extract according to the parts by weight;
weighing 5 parts of ammonium laureth sulfate, 5 parts of sodium laureth sulfate, 5 parts of cocamide DEA, 5 parts of cocamide MEA and 2 parts of cocamidopropyl betaine according to parts by weight, and mixing to obtain a surfactant mixture;
weighing 0.8 part of bacteriostatic agent, 0.1 part of sodium chloride, 0.1 part of magnesium nitrate, 0.5 part of polyquaternium-10, 0.5 part of DMDM hydantoin, 0.3 part of allantoin, 0.3 part of zinc pyrithione, 1 part of essence, 0.5 part of guar hydroxypropyl trimethyl ammonium chloride and 0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, wherein the bacteriostatic agent comprises 0.4 part of methyl chloro isothiazolinone and 0.4 part of methyl isothiazolinone.
The preparation method of the shampoo for preventing alopecia and removing dandruff is the same as that of the example 1.
First, irritation detection
The shampoo cream prepared in the embodiment 1-3 is sampled and is suitable for being smeared on the back of the hands of 100 volunteers aged 18-50 years, and is observed for 30min to see whether allergic phenomena such as red swelling, eruption, blistering and the like appear, and the observation result shows that: all volunteers have no allergy within 30min, which shows that the shampoo is mild and non-irritant, and does not cause irritation and allergy to skin.
Second, bacteriostatic effect
The shampoo prepared in examples 1 to 3 and comparative examples 1 to 4 were tested for bacteriostatic properties, and the bacterial species were provided by the institute for skin diseases in China. The test method comprises the following steps: the bacteriostatic effect detection is carried out by adopting a bacteriostatic ring method, the used strain is a pityrosporum Malassezia furfur ATCC 44344, the used culture medium is a Leeming and Notman agar culture medium, and the test result is shown in Table 1.
TABLE 1 results of tests on bacteriostatic properties of shampoos prepared in examples 1 to 3 and comparative examples 1 to 4
Diameter of bacterium (mm)
Example 1 19.1
Example 2 18.5
Example 3 18.7
Comparative example 1 15.4
Comparative example 2 14.3
Comparative example 3 14.9
Comparative example 4 14.1
As can be seen from the bacteriostatic effect of the table 1, the shampoos in the embodiments 1 to 3 of the invention have better inhibitory effect on malassezia, and the effect of the comparative examples 1 to 4 and the effect of the embodiment 1 are compared, so that the composition of the components in the natural extract can generate synergistic effect, and the inhibitory effect on the malassezia is obviously better than any one of the four.
Third, anti-dandruff effect
350 volunteers with dandruff and scalp itching problems were selected, randomly divided into 7 groups, and 50 individuals were selected, and the creams prepared in examples 1 to 3 and comparative examples 1 to 4 were used, respectively, and after use, the anti-dandruff and antipruritic effects of the creams were evaluated. The anti-dandruff effect is scored according to the amount and size of dandruff, and the anti-itching effect is scored according to the time when the head itch starts and the degree of the head itch. The evaluation period is 4 weeks, the evaluation is divided into 5 points, 5 points are the highest points, 1 point is the lowest point, and the higher the point is, the better the effect is. The evaluation results are shown in Table 2.
TABLE 2 results of the anti-dandruff antipruritic property test of the shampoos prepared in examples 1 to 3 and comparative examples 1 to 4
Cleanliness Degree of compliance Moisture retention Antidandruff property Richness of foam
Example 1 4.95 4.94 4.94 4.93 4.94
Example 2 4.94 4.93 4.94 4.91 4.94
Example 3 4.96 4.96 4.93 4.92 4.92
Comparative example 1 4.89 4.94 4.95 4.86 4.95
Comparative example 2 4.90 4.92 4.94 4.88 4.94
Comparative example 3 4.92 4.95 4.94 4.83 4.95
Comparative example 4 4.91 4.91 4.93 4.84 4.91
As can be seen from the effects of the table 2, compared with comparative examples 1 to 4, the anti-dandruff and itching-relieving effects of the shampoos in examples 1 to 3 are significantly better, and the anti-dandruff effect of the shampoo provided by the invention is significant due to the synergistic effect among the components in the natural extract adopted in the invention.
Fourth, the effect of preventing alopecia
The hair loss prevention effect of the shampoos prepared in examples 1 to 3 and comparative examples 1 to 4 was tested.
210 volunteers with average hair loss of more than 100/day were selected as subjects, randomly divided into 7 groups of 30 persons each, and the shampoos prepared in examples 1 to 3 and comparative examples 1 to 4 were tried respectively.
The test method comprises the following steps: the hair was washed every two days, combed 2 times in the morning and evening, the shed hair was collected and counted for a test period of 4 weeks (28 days), and finally the average was taken and the test results are shown in table 3.
TABLE 3 anti-alopecia test results of the shampoos prepared in examples 1-3 and comparative examples 1-4
As can be seen from the results in table 3, the shampoos prepared in examples 1 to 3 had significant anti-hair loss effect, and the average hair loss number per day was reduced to 85 or less after 4 weeks of use; the results of comparative examples 1 to 4 show that the components of the natural extract have synergistic effect, and the shampoo provided by the invention has remarkable anti-hair loss effect. In addition, it can be seen that the anti-hair loss effect of the shampoo in each example is different, which indicates that the ratio of each component in the important composition is different, and the anti-hair loss effect of the shampoo is also influenced to a certain extent.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (9)

1. The anti-hair loss and dandruff removing shampoo is characterized by comprising the following components in percentage by mass:
20-25% of a surfactant, 25-30% of a natural extract, 10-15% of an auxiliary agent and the balance of water;
the natural extracts include centella asiatica extract, rice fermentation product filtrate, scutellaria baicalensis root extract, and tea leaf extract.
2. The anti-hair loss and dandruff removing shampoo as claimed in claim 1, wherein the natural extract comprises the following components in parts by mass: 3-10 parts of a centella asiatica extract, 10-25 parts of a rice fermentation product filtrate, 3-15 parts of a scutellaria baicalensis root extract and 8-20 parts of a tea leaf extract.
3. The anti-hair loss and dandruff removing shampoo as claimed in claim 1 or 2, wherein the natural extract is composed of the following components in parts by mass: 5-8 parts of a centella asiatica extract, 15-20 parts of a rice fermentation product filtrate, 5-10 parts of a scutellaria baicalensis root extract and 10-15 parts of a tea leaf extract.
4. The shampoo for preventing hair loss and removing dandruff as claimed in claim 1 or 2, wherein the concentration of centella asiatica extract, scutellaria baicalensis root extract and tea extract is independently 0.8-1.5 g/mL.
5. The anti-hair loss and dandruff removing shampoo as claimed in claim 1, wherein the surfactant is composed of the following components in parts by mass: 5-20 parts of ammonium laureth sulfate, 5-20 parts of sodium laureth sulfate, 5-10 parts of cocamide DEA, 5-10 parts of cocamide MEA and 2-5 parts of cocamidopropyl betaine.
6. The anti-hair loss and dandruff removing shampoo as claimed in claim 1 or 5, wherein the surfactant is composed of the following components in parts by mass: 10-15 parts of ammonium laureth sulfate, 10-15 parts of sodium laureth sulfate, 7-8 parts of cocamide DEA, 7-8 parts of cocamide MEA and 3-4 parts of cocamidopropyl betaine.
7. The anti-hair loss and dandruff removing shampoo as claimed in claim 1, wherein the auxiliary agent comprises the following components in parts by mass: 0.8-2 parts of bacteriostatic agent, 0.1-0.2 part of sodium chloride, 0.1-0.2 part of magnesium nitrate, 0.5-0.8 part of polyquaternium-10, 0.5-0.8 part of DMDM hydantoin, 0.3-0.5 part of allantoin, 0.3-0.5 part of zinc pyrithione, 1-2 parts of essence, 0.5-0.8 part of guar gum hydroxypropyl trimethyl ammonium chloride and 0.5-0.8 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer.
8. The anti-hair loss and dandruff removing shampoo cream as claimed in claim 7, wherein the bacteriostatic agent comprises 0.4-1 part of methyl chloro isothiazolinone and 0.4-1 part of methyl isothiazolinone.
9. The preparation method of the anti-hair loss and dandruff removing shampoo as claimed in any one of claims 1 to 8, which is characterized by comprising the following steps:
mixing the natural extract, the surfactant, the auxiliary agent and water to obtain the anti-hair loss and dandruff removing shampoo.
CN201911021308.3A 2019-10-25 2019-10-25 Anti-hair loss and dandruff removing shampoo and preparation method thereof Pending CN110693777A (en)

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CN113842342A (en) * 2021-09-14 2021-12-28 广州锦同生物科技有限公司 Plant dandruff-removing and itching-relieving agent as well as preparation method and application thereof
CN114099402A (en) * 2021-11-19 2022-03-01 头道汤科技有限公司 Scalp cleaning and smoothing milk and preparation method thereof
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CN114558068A (en) * 2022-03-16 2022-05-31 薛辉 Preparation technology of ointment for removing dandruff and treating stubborn tinea and pruritus

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