KR101456655B1 - Preventing and Treating Composition for dandruff and itchy scalp - Google Patents

Abstract

The present invention relates to a composition for preventing and treating dandruff and itchy scalp. A herb medicine fermented liquor prepared according to the present invention removes unique smell of a herb medicine extract, has excellent usability because of little repulsion of children, and is effective in preventing dandruff and treating itchy scalp. Accordingly, a hair cosmetic composition such as a shampoo or a hair tonic including the herb medicine fermented liquor prepared according to the present invention can be effectively used for preventing dandruff and treating itchy scalp. Also, when applying the herb medicine fermented liquor prepared by using a nontoxic and safe ferment bacillus to a human body, the present invention can be safely used compared to an existing material.

Description

TECHNICAL FIELD The present invention relates to a composition for prevention and treatment of dandruff and scalp itch,

The present invention relates to a composition for preventing and treating dandruff and scalp itch. More particularly, the present invention relates to a composition for preventing and treating dandruff and scalp itching, which comprises a herbal fermentation broth obtained by fermenting a herbal medicine containing omija, alfalfa, green tea leaves, ginger and ginseng with lactic acid bacteria of Kimchi.

Dandruff usually refers to a type of dermatosis that occurs when the skin or skin that naturally falls off the scalp surface is covered with fat or dust. In addition, dandruff refers to an abnormal scalp state characterized by excessive keratinization of the scalp without accompanied by inflammation. Features of dandruff include small, dry, white dandruff scarring and irritant itching. If the hair follicle does not supply enough nutrition to the scalp due to deepening of the dandruff phenomenon, it develops as a cause of non-rigid hair loss .

The cause of dandruff has been attributed to dystonia, Pityrosporum Ovale , and most dandruff remedies have used zinc pyrithione or pyrrothonolamine to inhibit phytosphingoformals.

Causes of scalp inflammation include, but are not limited to, various pollutants, abnormal skin irritation to bacteria, excessive sebum production due to circulatory disorders such as endocrine abnormality, autonomic nervous system disorder, blood circulation disorder, hair follicle malnutrition, allergy, , Environmental factors such as genetic factors such as physical factors and hormonal effects and various pollution, food such as processed food, shampoo, soap, mousse hair gel, hair spray, permanent hair dye, hair dryer, detergent and excessive stress And mental factors due to the combination of these factors are known to appear.

In the case of hair cosmetics intended for the treatment and prevention of dandruff and scalp itching, it is possible to effectively inhibit the proliferation and activity of the yeast PHYTHROUS FORMOVALE, the main cause of dandruff, and to normalize the abnormal metabolism activity of the scalp cells Is required. In a study using herbal medicine extracts inhibiting the proliferation and activity of phytosphorus formovalere, the present inventors found that the fermentation broth fermented by inoculating Kimchi lactic acid bacteria with the above extract is effective for preventing dandruff and scalp itch without specific herbal medicine odor. .

It is an object of the present invention to provide a composition for treating and improving dandruff and scalp conditions that can prevent and treat dandruff and scalp itch as well as improve scalp condition. More specifically, the object of the present invention is to provide a composition for the treatment and improvement of dandruff and scalp conditions comprising an herbal fermented product having excellent effects on dandruff reduction and scaly itching, .

In order to accomplish the object of the present invention, in one embodiment of the present invention, there is provided a method for producing a ginger tea comprising 30 to 70 parts by weight of ginger, 2 to 20 parts by weight of omija, 5 to 40 parts by weight of an alabaster, 5 to 30 parts by weight of green tea leaves, 10 parts by weight of herbal medicine dried product was finely ground and 2 to 10 times of purified water of 100 parts by weight of the herbal powder was added and weissella cibaria ( KCTC 3746) , a fermented kimchi fermented lactic acid bacterium, was inoculated , And fermenting at 20 to 40 ° C for 24 hours to 48 hours to produce dandruff reduction and scalp itching inhibiting effect.

In another embodiment, there is provided a composition for improving dandruff and scalp itching comprising the herbal fermentation broth as an active ingredient. In this embodiment, the herbal fermentation broth comprises 2 to 4 parts by weight based on 100 parts by weight of the total composition. In this embodiment, the composition is a shampoo or a hair tonic.

The herbal fermentation broth according to the present invention is excellent in usability because it has little resistance to those used by eliminating the specific odor of herbal medicine extract, and has excellent effect of preventing dandruff and scalp itching symptoms. Accordingly, hair cosmetic compositions such as shampoos, hair tonics, etc. containing the herbal medicine fermentation liquid prepared according to the present invention can be effectively used for preventing dandruff and treating scalp itch. In addition, when a herbal fermented product produced using a safe fermenting bacteria free from toxicity is applied to a human body, it can be safely used as compared with the conventional method.

The fermenting bacteria which can be used in the present invention are lactobacillus ( Lactobacillus plantarum , Leuconostoc mesenteroides and Weissella < RTI ID = 0.0 > cibaria ). More preferably, as the above fermenting bacteria, Weissella cibaria ) strain.

As used in the present invention, 'Omiza' is a deciduous vine plant of Omiza, and contains ingredients such as isozyndrein, hypericin, citral, malic acid and citric acid to strengthen the heart, lower the blood pressure and improve the immunity, It is known that it strengthens the function and helps the cough and thirst by treatment of Jinhae and Gadam.

As used herein, the term " mulberry bark ", as a bark and root of mulberry, acts as a blood pressure lowering agent and is known to be good for hypertension and diabetes.

The 'green tea leaves' used in the present invention exhibit various effects such as antibacterial action and deodorization action, and are known to be excellent in sterilizing effect and effective in removing odor.

As used in the present invention, 'Gosam' is a perennial herb of soybean, and its roots are dried in a herb, and it tastes as gosam, and it tastes and is prescribed to digestive defects, neuralgia, hepatitis, jaundice and hemorrhoids. I used it as an analgesic.

As used in the present invention, 'ginger' is a root of perennial herbaceous plants belonging to the ginger family, and has a unique flavor and taste, and is one of the spices widely used in the world.

When the composition for preventing and treating dandruff and scalp itching according to the present invention is a medicinal composition, it is preferable to apply the appropriate amount in morning and evening according to the once-a-day to several-times returning with a usual external agent such as ointment or cream .

The composition of the present invention may have conventional formulations and may be formulated into, for example, shampoos, rinses, hair tonics, hair treatments, and the like. The composition of each of these formulations may contain a variety of agents and additives that are necessary and appropriate for the formulation of the formulation, and the type and amount of these ingredients may be readily selected by those skilled in the art. Hereinafter, typical base ingredients and additives will be described by taking as an example the composition of a typical ophthalmic formulation of a hair cosmetic composition. For example, in the case of having an ointment formulation, it may be a shampoo composition including a synthetic surfactant which is a cleaning component and preservatives, thickeners and viscosity regulators, pH adjusting agents, flavors, dyes, hair conditioning agents and water, As the active agent, any selected from anionic, amphoteric, nonionic, and cationic surfactants is usable, and these surfactants may be contained in an amount of 10 to 50% by weight, more preferably 10 to 30% by weight of the composition .

Hereinafter, the components and technical features of the present invention will be described in more detail with reference to the following examples. However, the following examples are intended to illustrate the contents of the present invention and are not intended to limit the scope of the invention.

Manufacture of Fermentation Liquid Derived from Natural Products

50 parts by weight of ginger, 10 parts by weight of omega, 20 parts by weight of corn syrup, 15 parts by weight of green tea leaves and 5 parts by weight of ginseng were finely pulverized on the basis of the whole herbal extract (100 parts by weight). Thereafter, 2 to 10 times of purified water of 100 parts by weight of the total dry raw material was added. The kimchi fermenter, Weissella cibaria , KCTC 3746) were inoculated and fermented in a shaking incubator at 20 to 24 ° C and 24 to 48 hours. The fermented product was centrifuged at 20 ° C and 5000 rpm for 20 minutes to remove the solid matter of the herbal medicine and the culture solution, and the supernatant was taken to prepare a herbal fermentation broth. A composition comprising 2 parts by weight (Example 1) or 4 parts by weight (Example 2) of the herbal fermentation broth was prepared in comparison with the whole composition (100 parts by weight).

Experimental Example  1. Comparison test of antimicrobial activity against sickle cells of herbal medicine fermentation broth

In order to measure the antimicrobial activity of the fermentation broth of Example 1 described above, each of the samples listed in the following table was inoculated with agar dilution method (agar dilution), incubated at 37 ° C in an anaerobic condition for 48 hours, Was determined as the minimum growth inhibitory concentration (MIC), and the antibacterial activity was measured. In the determination, the well in which the inoculated bacteria propagated is positive (+) and the well not proliferated is marked as negative (-). At this time, the concentration of the sample in the first well in which the inoculating bacteria did not proliferate is defined as MIC. Table 1 shows the results of measurement of anticlastic activity according to the content of herbal fermentation broth.

MIC measurement Dilution concentration of herbal fermentation broth 8% 4% 2% One% 0.5% 0.1% - - + + + +

As shown in Table 1, the MIC of the herbal fermentation broth is 4%.

Experimental Example  2. Measurement of effect of cosmetic composition (shampoo formulation) containing fermented extract

As shown in Table 2 below, cosmetic compositions of shampoo formulations containing the fermented extract of the present invention were prepared.

Shampoo composition (unit: parts by weight) Raw material name Comparative Example 1 Example 1 Example 2 Ammonium laureth sulfate 17 17 17 Cocoyl diethanolamide 13 13 13 Cocamide miai 5 5 5 Disodium laureth sulfosuccinate 5 5 5 Cocamidopropyl betaine 10 10 10 Propylene glycol 4 4 4 Sodium lauryl oxyethylene sulfate 4 4 4 Ethylene glycol monostearate 3 3 3 Sodium chloride One One One Guar hydroxypropyltrimonium chloride 0.7 0.7 0.7 Polyquaternium-10 0.7 0.7 0.7 menthol 0.1 0.1 0.1 Panthenol 0.5 0.5 0.5 Disodium iodide 0.1 0.1 0.1 Mineral oil 0.05 0.05 0.05 lecithin 0.05 0.05 0.05 Spices Suitable amount Suitable amount Suitable amount Herbal fermentation broth - 2 4 Purified water Lt; RTI ID = 0.0 > 100 parts < / RTI &
Weight portion Lt; RTI ID = 0.0 > 100 parts < / RTI &
Weight portion Weight parts added such that the total composition is 100 parts by weight synthesis 100 100 100

Experimental Example  2.1 Measurement of dandruff reduction rate

Ten men and women with relatively large amounts of dandruff were selected, and the shampoos of Comparative Example 1, Example 1 and Example 2 in Table 2 were used for 20 days, respectively. Before the start of the test, the dandruff was sampled with a normal shampoo and collected for 3 days. The dandruff weight was sampled once each day with the shampoo of the examples and comparative examples, and the dandruff weight accumulated for 3 days after the test was compared Respectively.

At this time, the accumulated dandruff was sampled by a skilled tester using a shampoo of about 5 g, then washed with about 2 to 3 liters of water, and the washed water was filtered with 800 micro-pore size The dry weight of the dandruff on the filter was sieved, and the dandruff reduction rate was determined by the following equation, and the results are shown in Table 3.

(%) = [(Weight of pre-test dandruff (mg) - weight of dandruff (mg) 1 month after start of test) / weight of pre-test dandruff (mg)] x 100

Results of dandruff reduction rate measurement division Comparative Example 1 Example 1 Example 2 Dandruff reduction rate 0.5% 12.2% 32.3%

As shown in Table 3, the dandruff reduction rate was much higher than that of the shampoo containing no herbal fermentation broth according to the present invention, and the dandruff reduction rate was increased as the content of the herbal fermentation broth increased.

Experimental Example  2.2 Assessment of dandruff prevention effect and itching reduction effect

20 randomly selected men and women who usually feel dandruff and itching were randomly selected to use the shampoo of Comparative Example 1, Example 1 and Example 2 of Table 2 for 10 days for each product once a day for 10 days, Dandruff prevention effect and itching reduction effect were evaluated according to the following criteria (Table 4 and Table 5), and the average values thereof are shown in Tables 6 and 7. < tb > < TABLE >

Dandruff Prevention Criteria division score Dandruff prevention effect is very good 5 Good anti-dandruff effect 4 The dandruff effect is normal. 3 There is little dandruff effect 2 There is no anti-dandruff effect. One

Criteria for reducing itching division score Itching effect is very good 5 Good for reducing itching 4 The itching effect is normal. 3 There is a slight reduction in itching 2 There is no effect of reducing itching One

Anti-dandruff effect division Comparative Example 1 Example 1 Example 2 Anti-dandruff effect 0 1.2 3.5

Scalp itching reduction effect division Comparative Example 1 Example 1 Example 2 Scalp itching
Reduction effect 0 2.2 3.7

As shown in Tables 6 and 7, when the herbal fermentation broth was added at 2% or 4%, it was confirmed that there was a significant dandruff preventing effect and scalp itching reduction effect.

Experimental Example  3. Measurement of effect of cosmetic composition (hair tonic formulation) containing fermented extract

As shown in Table 8 below, a hair tonic cosmetic composition containing the fermented extract of the present invention was prepared.

Hairtonic composition (unit: parts by weight) Raw material name Comparative Example 2 Example 3 Example 4 ethanol 50 50 50 L-menthol 0.05 0.05 0.05 Propylene glycol One One One Panthenol 0.5 0.5 0.5 Polyoxyethylene hardened castor oil 0.5 0.5 0.5 Spices Suitable amount Suitable amount Suitable amount Citric acid Suitable amount Suitable amount Suitable amount Herbal fermentation broth - 2 4 Purified water 100 parts by weight of the total composition
Weight added 100 parts by weight of the total composition
Weight added 100 parts by weight of the total composition
Weight added synthesis 100 100 100

Experimental Example  3.1 Measurement of dandruff reduction rate

Ten male and female dandelions were selected, and the hair tonics of Comparative Example 2, Example 3 and Example 4 in Table 8 were used for 20 days, respectively. Before the start of the test, the hair was smeared with a normal shampoo and collected for 3 days. The collected dandruff was weighed and the test was performed using the hair tonic according to Table 5 twice a day twice daily while shaking the hair with usual shampoo once a day The dandruff weight accumulated over 3 days was compared and evaluated. During this test period, the shampoo used a general shampoo with no dandruff inhibiting activity.

At this time, the collected dandruff can be measured by a skilled tester using a shampoo of about 5 g, followed by rinsing with about 2 to 3 liters of water. The washed water is then filtered through an 800 micro-pore size filter The dry weight of the dandruff on the filter paper was measured, and the dandruff reduction rate was determined by the following equation, and the results are shown in Table 6.

(%) = [(Weight of the dandruff before the test (mg) - weight of the dandruff (mg) 1 month after the start of the test) / weight of the dandruff before the test (mg)] × 100

Dandruff reduction effect division Comparative Example 2 Example 3 Example 4 Dandruff reduction rate 0.2% 15.2% 52.3%

Table 9 shows that the reduction rate of dandruff was much higher than that of the hair tonic not including the hair tonic containing the herbal fermentation liquid according to the present invention, and the dandruff reduction rate also increased as the content of the herbal fermentation broth increased. The use of hair tonic was more effective than dandruff shampoo in reducing dandruff.

Experimental Example  3.2 Dandruff prevention effect and itching reduction effect

The anti-dandruff effect and the itching effect of the hair tonic compositions shown in Table 3 were measured according to the criteria described in Tables 4 and 5 above.

Anti-dandruff effect division Comparative Example 2 Example 3 Example 4 Anti-dandruff effect 0 1.3 2.9

Scalp itching reduction effect division Comparative Example 1 Example 1 Example 2 Scalp itching
Reduction effect 0 2.8 4.3

As shown in the results of Table 10 and Table 11, it was confirmed that when 2% or 4% of herbal liquid fermentation broth was added, there was a significant dandruff preventing effect and scalp itching reduction effect.

While the present invention has been described with reference to exemplary embodiments, those skilled in the art will be able to make various changes without departing from the scope of the invention, . In addition, many modifications may be made to adapt a particular situation and material to the teachings of the invention without departing from the essential scope thereof. Accordingly, it is intended that the invention not be limited to the particular embodiment disclosed as the best mode contemplated for carrying out this invention, but that the invention will include all embodiments falling within the scope of the appended claims.

Claims (4)

100 parts by weight of herbal medicine dried material containing 40 to 60 parts by weight of ginger, 5 to 15 parts by weight of omija, 10 to 30 parts by weight of herbal tea, 10 to 20 parts by weight of green tea leaves and 2 to 8 parts by weight of ginseng is finely pulverized, A dandruff reduction produced by adding 2 to 10 times of purified water to 100 parts by weight of water and inoculating with Weissella cibaria ( KCTC 3746) and fermenting at 20 to 40 DEG C for 24 to 48 hours in a shaking incubator And a method for producing a herbal fermentation broth having a scalp itching inhibiting effect.
The herbal medicine dried product comprising 40 to 60 parts by weight of ginger, 5 to 15 parts by weight of omija, 10 to 30 parts by weight of an alabaster, 10 to 20 parts by weight of green tea leaves and 2 to 8 parts by weight of high ginseng was treated with Weissella cibaria ( KCTC 3746 ) At 20 to 40 째 C for 24 to 48 hours as an active ingredient. The composition for improving dandruff and scalp itching comprises a herbal fermentation broth having dandruff reduction and scalp itching inhibitory effect.
3. The method of claim 2,
Wherein the herbal fermentation broth comprises 2 to 4 parts by weight based on 100 parts by weight of the total composition.
3. The method according to claim 2 or 3,
A composition for improving dandruff and scalp itching, characterized in that the composition is a shampoo or a hair tonic.