CN115569105A

CN115569105A - Composition containing rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites

Info

Publication number: CN115569105A
Application number: CN202211490496.6A
Authority: CN
Inventors: 范新雨; 熊源泉; 张平; 范明; 刘雨辉; 黄犟兵; 何方舟; 张锋
Original assignee: Jiangxi Bajiu New Material Technology Co ltd; Guangzhou Heli Biotechnology Co ltd
Current assignee: Jiangxi Bajiu New Material Technology Co ltd
Priority date: 2022-11-25
Filing date: 2022-11-25
Publication date: 2023-01-06
Anticipated expiration: 2042-11-25
Also published as: CN115569105B

Abstract

The invention discloses a composition containing a rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites, which relates to the field of daily chemicals and comprises the following components in parts by weight: 0.5-5 parts of rice hull extract, 0.1-1 part of silver-containing antibacterial agent, 0.1-0.6 part of white willow bark extract, 1-5 parts of cacumen biotae extract, 0.2-0.8 part of soybean lecithin and 0.1-3 parts of lactobacillus fermentation lysate. The rice hull extract, the silver-containing antibacterial agent, the white willow bark extract, the cacumen biotae extract, the soybean lecithin and the lactobacillus fermentation lysate are matched for use, and the obtained composition has good effects of controlling oil, removing dandruff, inhibiting bacteria and removing mites, and is mild and non-irritant.

Description

Composition containing rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites

Technical Field

The invention belongs to the field of daily chemicals, and particularly relates to a composition containing a rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites.

Background

Dandruff occurs mainly due to the destruction of the lipid, flora and metabolic balance of the scalp. The healthy scalp ecosystem is maintained by three major balances: oil, flora and metabolic balance. When the scalp grease secretion is unbalanced and the scalp grease secretion is excessive, the scalp becomes greasy; when the scalp flora is unbalanced in environment and a large amount of harmful bacteria are bred, the phenomenon of itching can occur; the stratum corneum of the scalp is metabolized too quickly, and falls off to form dandruff. Abnormal activity of malassezia is also believed to be one of the major causes of dandruff formation. In addition, there are data showing that the presence of mites has a certain effect on sebum lipid secretion, dandruff and abnormal hair loss. After the mites are bred on the scalp, the skin sebaceous glands are stimulated to secrete a large amount of oil, and the oil secretion imbalance appears, so that the problems of excessive oil secretion and the like can be balanced radically only by comprehensively, systematically and scientifically conditioning and maintaining the scalp, and the healthy normality of the scalp is kept.

Although a plurality of shampoos alleged to have the functions of removing dandruff and controlling oil are available in the market, the effect is poor, dandruff is more after some shampoos are used, and the scalp is itchy. Most shampoos on the market today do not really remove dandruff because they are cosmetic in nature, and their basic function is only cleansing and not effective in killing microorganisms on the skin surface. The formula contains the active ingredients for inhibiting bacteria and removing mites, so that the propagation of fungi can be inhibited, and the breeding of the mites can be effectively controlled, thereby effectively conditioning the scalp environment and helping to relieve the scurf problem. Therefore, it is a current trend to add natural active substances having bacteriostatic and acaricidal effects to alleviate the above problems.

The patent (CN 115006267A) discloses a composition for removing dandruff and controlling oil, which comprises the following components in parts by weight: 0.1-7 parts of white willow bark extract, 0.1-5 parts of peony root extract and 0.02-0.5 part of colloidal silver. The anti-dandruff oil-control composition has a synergistic effect by compounding colloidal silver, the salix alba extract and the peony root extract, so that the composition has a remarkable anti-inflammatory anti-dandruff oil-control effect.

The patent (CN 114617805A) discloses a hair growth functional shampoo taking cacumen biotae liposome as a core, which can promote the rapid growth of hair and blacken the hair while treating alopecia. The shampoo does not contain preservative and hormone, has no stimulation to scalp, has good treatment effect and quick response, and has certain effects of removing dandruff and relieving itching.

The patent (CN 110876695A) discloses a probiotic bacteria dandruff-removing shampoo, which contains inactivated lactobacillus paracasei, maltotetraose and soybean oil, and helps to restore the microecological balance of scalp flora and radically solve the dandruff problem by jointly using the inactivated lactobacillus paracasei, the soybean oil and the maltotetraose.

Patent No. 111096940 discloses a mild, healthy, long-lasting-efficacy shampoo preparation for removing mites and relieving itching. The shampoo preparation comprises the following components by weight: surfactant, softener, thickener, zinc sulfate, acrylic acid (ester) copolymer, glycerol, zinc pyrithione, essence, ethoxy diglycol, sweet wormwood herb extract, conditioner for hair, preservative, purified water and pH regulator, wherein the pH value of the regulating system is 6-7. Because the sweet wormwood herb extract is added for removing the mites, the purposes of persistent itching relieving, bacteriostasis and mite removal can be achieved, and the scalp and the hair are not injured.

The patent (CN 111686049A) provides an antibacterial mite-killing shampoo, which comprises the following raw materials: sodium laureth sulfate, decyl glucoside, behenamidopropyl dimethylamine, cocamide MEA, polyquaternium-52, cocamidopropyl betaine, common jujube bark extract, piroctone olamine, gentian extract, guar hydroxypropyltrimonium chloride, polyquaternium-10, cnidium fruit extract, dimethiconol, amodimethicone, plant extract, niacinamide, hydroxyethyldiphosphonic acid, carbomer, sodium hydroxide, preservative, essence, hexamidine di (isethionic acid) salt, menthol and water; wherein the plant extract is flos Caryophylli bud extract, fructus Zanthoxyli extract, herba Thymi extract and radix Sophorae Flavescentis extract. The shampoo obtained by mutually matching the components and optimizing the preparation method has good bacteriostatic and mite-killing effects.

Although the prior art has certain improvement on removing the dandruff and the mites, the adopted active substances have the same or similar functions, and the improvement degree is still limited. Therefore, it is necessary to provide a hair washing and caring product with excellent effects of removing dandruff, controlling oil, inhibiting bacteria and removing mites. Researches show that the newly developed new raw material rice hull extract can inhibit scurf caused by malassezia, has the mite killing rate of 99.99 percent, and is a novel mite remover with higher cost performance and natural plant sources. Therefore, the application aims to provide the composition containing the rice hull extract for removing the oil, controlling the bacteria and removing the mites, and the good effects of controlling the oil, removing the dandruff, controlling the bacteria and removing the mites are realized.

Disclosure of Invention

Aiming at the problems in the prior art, the invention provides a composition containing a rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites. The rice hull extract, the silver-containing antibacterial agent, the white willow bark extract, the cacumen biotae extract, the soybean lecithin and the lactobacillus fermentation lysate are matched for use, and the obtained composition has good effects of controlling oil, removing dandruff, inhibiting bacteria and removing mites, and is mild and non-irritant.

In order to realize the purpose, the technical scheme adopted by the invention is as follows:

in a first aspect, the invention provides a composition containing a rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites, which is characterized by comprising the following components in parts by weight: 0.5-5 parts of rice hull extract, 0.1-1 part of silver-containing antibacterial agent, 0.1-0.6 part of white willow bark extract, 1-5 parts of cacumen biotae extract, 0.2-0.8 part of soybean lecithin and 0.1-3 parts of lactobacillus fermentation lysate.

The rice hull extract contains various components such as organic acid, polyphenol and the like, is a natural antibacterial agent, and has the functions of inhibiting bacteria and removing mites. Silver in the silver-containing antibacterial agent breaks cell walls by destroying charge balance of bacterial cell walls and is chelated at active sites of protease in cells for sterilization, and the silver-containing antibacterial agent also has a certain effect on malassezia. The main active substance of the white willow bark extract is salicin which has the functions of diminishing inflammation, inhibiting bacteria, removing dead skin, supplementing skin moisture, enhancing the moistening degree of the skin and increasing the barrier function of the skin. The cacumen biotae extract has the pharmacological effects of inhibiting bacteria, resisting inflammation, dilating blood vessels, removing dandruff, preventing alopecia, proliferating beard and hair and the like. Soybean lecithin directly contacts skin cells, and can enter deep skin through transdermal absorption to repair damaged cell membrane and improve organism regeneration capability. The lactobacillus fermentation lysate has the effects of resisting oxidation, protecting and repairing human skin fibroblasts, improving collagen production, preserving moisture and the like. The rice hull extract, the silver-containing antibacterial agent and the white willow bark extract have good antibacterial action, the cacumen biotae extract and the lactobacillus fermentation lysate can effectively repair scalp, and the oil control effect is good, and the rice hull extract also has excellent mite removing effect.

Through the matching use of the components, particularly the rice hull extract, the silver-containing antibacterial agent, the white willow bark extract, the cacumen biotae extract and the lactobacillus fermentation lysate, on one hand, the damaged scalp can be repaired, the inflammation of the scalp can be eliminated, and the scalp can be recovered to be healthy, on the other hand, microorganisms on the surface of the scalp can be effectively killed, the fungus reproduction can be inhibited, the breeding of mites can be controlled, the scalp flora environmental balance can be maintained, on the third hand, the skin moisture can be supplemented, the skin moistening degree can be enhanced, and the skin barrier function can be increased, so that the scalp can be comprehensively, systematically and scientifically conditioned and maintained, the scalp problems such as head oil, scurf and the like can be eliminated from the root source, and the healthy normal state of the scalp can be maintained.

In addition, the organic components such as acids, polyphenols, alcohols and the like contained in the rice hull extract have certain inhibition capability on malassezia and other pathogenic bacteria. The preservative has a synergistic effect on the existing preservative system when added into a product, and the dosage of the preservative can be properly reduced.

Preferably, the silver-containing antimicrobial agent is the model AgD538.

Further, the composition also comprises the following components in parts by weight: 0.1 to 0.5 portion of allantoin and 0.15 to 1.25 portions of preservative.

Preferably, the preservative is selected from methylparaben and/or phenoxyethanol.

Preferably, the preservative is methyl hydroxybenzoate and phenoxyethanol, and the mass ratio of the methyl hydroxybenzoate to the phenoxyethanol is 0.05-0.25.

Further, the composition also comprises the following components in parts by weight: 0.05-0.3 part of EDTA disodium, 1-6 parts of organic solvent and 0.2-0.7 part of solubilizer.

Preferably, the organic solvent is methyl propylene glycol, and the solubilizer is hydrogenated castor oil CO40.

Further, the composition also comprises a pH value regulator, essence and pure water.

Preferably, the pH value regulator is arginine, the pure water is selected from distilled water and/or deionized water, and the essence is selected from at least one of costustoot, flower fragrance and marine flavor.

Preferably, the composition comprises the following components in percentage by mass:

on the other hand, the invention also provides a preparation method of the composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites, which is characterized by comprising the following steps: the method comprises the following steps:

(1) Adding pure water with formula ratio into a stirring pot, heating, adding powdery raw materials of EDTA disodium, allantoin and methylparaben, heating, preserving heat and cooling to obtain phase A;

(2) Adding cacumen Platycladi extract, soybean lecithin, lactobacillus fermentation lysate and white willow bark extract into organic solvent, and stirring to obtain phase B;

(3) And adding the phase B into the phase A when the temperature of the materials in the stirring pot is reduced to be within 50 ℃. Cooling to below 45 deg.C, adding testa oryzae extract, phenoxyethanol, silver-containing antibacterial agent, essence and solubilizer, adjusting pH with pH regulator until pH is 6.2-6.8, and discharging.

Preferably, in the step (1), the mixture is heated to 80 ℃ and kept for 10 minutes.

Finally, the invention also provides the application of the composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites in the preparation of cosmetics with the effect of repairing scalp.

Compared with the prior art, the invention has the following beneficial effects:

1. the invention adopts a plurality of active ingredients of rice hull extract, silver-containing antibacterial agent, white willow bark extract, cacumen biotae extract, soybean lecithin and lactobacillus fermentation lysate to be matched for use, on one hand, the damaged scalp can be repaired, inflammation of the scalp can be eliminated, and the scalp can be recovered to be healthy, on the other hand, microorganisms on the surface of the scalp can be effectively killed, fungus reproduction can be inhibited, breeding of mites can be controlled, and scalp flora environmental balance can be maintained through a plurality of action mechanisms, on the third hand, skin moisture can be supplemented, skin moistening degree can be enhanced, and skin barrier function can be increased, so that comprehensive, systematic and scientific conditioning and maintenance can be realized on the scalp, scalp problems such as head oil, head scurf and the like can be eliminated radically, healthy and normal state of the scalp can be maintained, and the obtained composition has good effects of oil control, scurf removal, bacteriostasis and mite removal, and is mild and has no stimulation.

2. The rice hull extract contains organic components such as acids, polyphenols, alcohols and the like, and has certain inhibition capacity on malassezia and other pathogenic bacteria. The preservative has a synergistic effect on the existing preservative system when added into a product, and the dosage of the preservative can be properly reduced.

3. The functional components adopted by the composition of the invention are hormone-free, mild, free of side effect and simple to use.

Detailed Description

It should be noted that the raw materials used in the present invention are all common commercial products, and the sources thereof are not particularly limited.

The following sources of raw materials are exemplary:

rice hull extract: husk 101H, available from Jiangxi Bajiu New Material science and technology Co., ltd;

silver-containing antibacterial agents: agD538, available from dimei biotechnology ltd, guangzhou;

white willow bark extract: salix ALBA (Salix ALBA) bark extract, available from Guangzhou Kaibo Biotech limited;

biota orientalis leaf extract: biota ORIENTALIS (PLATYCLADUS ORIENTALIS) leaf extract, available from Yunnan white bioscience, guangzhou;

soybean lecithin: lysofit, available from nanotechnology, inc;

lactic acid bacteria fermentation lysate: proRenew Complex CLRTM, available from Guangzhou Yangzhou Biotech Inc.;

essence: floral, commercially available;

pH regulator: arginine, commercially available;

solubilizer: hydrogenated castor oil CO40, commercially available;

preservative: methylparaben, phenoxyethanol, commercially available;

EDTA disodium, allantoin, methylparaben, methyl propylene glycol, phenoxyethanol, deionized water: it is commercially available.

Example 1

The formula of the composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites in this example is shown in table 1.

The preparation process comprises the following steps:

(1) Adding deionized water according to the formula amount into a stirring pot, heating, adding powdery raw materials of EDTA disodium, allantoin and methylparaben, heating to 80 ℃, preserving heat for 10 minutes, and cooling to obtain a phase A;

(2) Adding folium Platycladi extract, soybean lecithin, lactobacillus fermentation lysate and white willow bark extract into methyl propylene glycol, and stirring to obtain phase B;

(3) And adding the phase B into the phase A when the temperature of the materials in the stirring pot is reduced to be within 50 ℃. Cooling to below 45 deg.C, adding testa oryzae extract, phenoxyethanol, silver-containing antibacterial agent, essence, and CO40, adjusting pH with arginine until the pH value is 6.2-6.8, and discharging.

Example 2

The formula of the composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites in this example is shown in table 1, and the preparation process is the same as that in example 1.

Example 3

Comparative example 1

The procedure of example 1 was repeated except that rice hull extract was used instead of white willow bark extract and silver-containing antibacterial agent was used.

Comparative example 2

The same as in example 1 was repeated except that rice hull extract was used instead of white willow bark extract.

Comparative example 3

The procedure of example 1 was repeated except that the silver-containing antibacterial agent was replaced with the rice hull extract.

Comparative example 4

The same procedure as in example 1 was repeated except that the cell lysate obtained by fermentation with lactic acid bacteria was used instead of the silver-containing antibacterial agent, the rice hull extract and the white willow bark extract.

Comparative example 5

The procedure of example 1 was repeated, except that 0.34g of a silver-containing antibacterial agent, 1.02g of an extract of rice husk and 0.14g of an extract of white willow bark were used in place of the lactic acid bacteria fermentation lysate.

Comparative example 6

The procedure of example 1 was repeated except that the cacumen Platycladi extract was used instead of the silver-containing antibacterial agent, the rice hull extract, the white willow bark extract, and the lactic acid bacteria fermentation lysate.

Comparative example 7

The procedure of example 1 was repeated, except that 0.51g of a silver-containing antibacterial agent, 1.53g of an extract of rice husk, 0.2g of an extract of white willow bark and 0.76g of a lactic acid bacterium fermentation lysate were used in place of the extract of cacumen Platycladi.

TABLE 1 formula of composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites of examples 1-3 and comparative examples 1-5

Application example

1. Oil control evaluation: 14 individuals with scalp problems were selected and oil control evaluation tests were sequentially conducted on the compositions of each example and comparative example in a 7-day cycle. For example, after 7 days from the time when 14 persons were collectively participating in the oil control evaluation test of the composition of example 1 (hair and scalp were cleaned with a base shampoo), 14 persons were further participating in the oil control evaluation test of the composition of example 2, and the results were obtained by averaging the oil control times of 14 persons after the completion of the test. Before each sample plate is tested, firstly, cleaning hair and scalp by using basic shampoo which is specially provided twice (the basic shampoo does not contain an anti-dandruff agent, an anti-mite agent and an oil control component), continuously using for two days, drying the hair after the second washing, uniformly smearing the scalp by using a graduated tip bottle which is filled with the anti-dandruff oil control, anti-bacteria and anti-mite composition, massaging until the scalp is absorbed, wherein the usage amount is 10ml each time, and the retention time of the refreshing degree of the scalp is tested, namely the oil control time, and the specific method is as follows: inserting fingers into hair or hair roots, and judging according to the greasiness degree of the fingers, wherein the fingers are not greasy and are fresh. Day 0.5 is the test unit and each composition is observed for differences, giving the corresponding oil control time for each composition.

2. Evaluation of dandruff removal and bacteriostasis: abnormal activity of malassezia is also considered to be a main reason for dandruff formation, so the dandruff removing effect is evaluated through the malassezia bacteriostasis rate, and the test is carried out according to the evaluation method for the antibacterial and bacteriostatic effect of the light industry standard QB/T2738-2012 daily chemical products of the people's republic of China, the action concentration is 1%, and the action time is 10min.

3. Mite removal evaluation: with reference to NY/T1151.2-2006, sample pre-treatment: adding mite (dust mite) into 5mL of sample stock solutionDermatophagoides farinaeFemale and male adult mites and nymph), and acts for 48 hours.

TABLE 2 oil control, anti-dandruff, bacteriostatic and anti-mite results for the compositions of examples 1-3 and comparative examples 1-7

As can be seen from the table 2, the anti-dandruff oil-control and anti-bacteria mite-removing composition prepared in the examples 1 to 3 of the application has excellent effects of controlling bacteria, removing mites, controlling oil and removing dandruff, wherein the comprehensive effect of the example 1 is the best, and the comprehensive improvement effects of the comparative examples 1 to 7 are poor due to the lack of one or more important components.

Finally, it should be noted that the above-mentioned contents are only used for illustrating the technical solutions of the present invention, and do not limit the protection scope of the present invention, and those skilled in the art can make simple modifications or equivalent substitutions on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. A composition containing a rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites is characterized by comprising the following components in parts by weight: 0.5-5 parts of rice hull extract, 0.1-1 part of silver-containing antibacterial agent, 0.1-0.6 part of white willow bark extract, 1-5 parts of cacumen biotae extract, 0.2-0.8 part of soybean lecithin and 0.1-3 parts of lactobacillus fermentation lysate; wherein the silver-containing antimicrobial agent is AgD538.

2. The composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites according to claim 1, which is characterized by further comprising the following components in parts by weight: 0.1 to 0.5 portion of allantoin and 0.15 to 1.25 portions of preservative.

3. A composition according to claim 2, wherein the preservative is selected from methylparaben and/or phenoxyethanol.

4. A composition according to claim 3, wherein the preservative is methylparaben and phenoxyethanol, and the mass ratio of methylparaben to phenoxyethanol is (0.05-0.25) to (0.1-1).

5. The composition for removing dandruff, controlling oil, inhibiting bacteria and removing mites according to claim 1, which is characterized by further comprising the following components in parts by weight: 0.05-0.3 part of EDTA disodium, 1-6 parts of organic solvent and 0.2-0.7 part of solubilizer.

6. A composition according to claim 5, wherein the organic solvent is methyl propylene glycol.

7. A composition according to claim 5, wherein the solubilising agent is hydrogenated castor oil CO40.

8. A composition according to claim 1, further comprising pH modifier, perfume and purified water.

9. A composition according to claim 8, wherein the pH regulator is arginine and the purified water is selected from distilled water and/or deionized water.

10. The composition according to claim 8, wherein the essence is at least one of radix aucklandiae, flowery odour and marine flavor.

11. A composition containing rice hull extract for removing dandruff, controlling oil, inhibiting bacteria and removing mites is characterized by comprising the following components in parts by weight:

wherein the silver-containing antimicrobial agent is AgD538.

12. A method of preparing a composition according to claim 11, wherein the composition comprises: the method comprises the following steps:

1) Adding pure water with formula ratio into a stirring pot, heating, adding powdery raw materials of EDTA disodium, allantoin and methylparaben, heating, preserving heat and cooling to obtain phase A;

2) Adding cacumen Platycladi extract, soybean lecithin, lactobacillus fermentation lysate and white willow bark extract into organic solvent, and stirring to obtain phase B;

3) And (3) when the temperature of the materials in the stirring pot is reduced to be within 50 ℃, adding the phase B into the phase A, reducing the temperature to be below 45 ℃, adding the rice hull extract, phenoxyethanol, silver-containing antibacterial agent, essence and solubilizer, adjusting the pH value by using a pH regulator until the pH value is 6.2-6.8, and discharging after the detection is qualified.

13. The method according to claim 12, wherein in the step (1), the mixture is heated to 80 ℃ and kept at the temperature for 10 minutes.

14. Use of a composition according to any one of claims 1 to 11 for removing dandruff, controlling oil, inhibiting bacteria and removing mites for the preparation of a cosmetic product having a scalp-repairing effect.