CN113543811A - 制剂中的人血清白蛋白 - Google Patents

制剂中的人血清白蛋白 Download PDF

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Publication number
CN113543811A
CN113543811A CN202080018514.3A CN202080018514A CN113543811A CN 113543811 A CN113543811 A CN 113543811A CN 202080018514 A CN202080018514 A CN 202080018514A CN 113543811 A CN113543811 A CN 113543811A
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formulation
fatty acid
polysorbate
protein
particles
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Pending
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CN202080018514.3A
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Chinese (zh)
Inventor
D·金
M·马洛
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN202080018514.3A 2019-03-05 2020-03-03 制剂中的人血清白蛋白 Pending CN113543811A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962813843P 2019-03-05 2019-03-05
US62/813,843 2019-03-05
PCT/US2020/020752 WO2020180850A1 (en) 2019-03-05 2020-03-03 Human serum albumin in formulations

Publications (1)

Publication Number Publication Date
CN113543811A true CN113543811A (zh) 2021-10-22

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ID=70190088

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080018514.3A Pending CN113543811A (zh) 2019-03-05 2020-03-03 制剂中的人血清白蛋白

Country Status (13)

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US (2) US11241499B2 (https=)
EP (1) EP3934620A1 (https=)
JP (2) JP7561748B2 (https=)
CN (1) CN113543811A (https=)
AU (2) AU2020232683B2 (https=)
BR (1) BR112021015790A2 (https=)
CA (1) CA3130457A1 (https=)
EA (1) EA202192422A1 (https=)
IL (2) IL321704A (https=)
MX (1) MX2021010558A (https=)
SG (1) SG11202109004TA (https=)
WO (1) WO2020180850A1 (https=)
ZA (1) ZA202106012B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202192422A1 (ru) 2019-03-05 2021-12-09 Ридженерон Фармасьютикалз, Инк. Человеческий сывороточный альбумин в составах
CN116457020A (zh) * 2020-11-16 2023-07-18 W.L.戈尔及同仁股份有限公司 不含脂肪酸颗粒的制剂、方法和预填充注射装置
KR20240021921A (ko) * 2021-06-14 2024-02-19 리제너론 파아마슈티컬스, 인크. 초고감도 비추출 지방산 정량화 방법을 사용한 제약 제형 중 폴리소르베이트 가수분해 모니터링

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108472379A (zh) * 2015-12-30 2018-08-31 豪夫迈·罗氏有限公司 减少聚山梨酯降解的制剂

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