CA3130457A1 - Human serum albumin in formulations - Google Patents

Human serum albumin in formulations Download PDF

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Publication number
CA3130457A1
CA3130457A1 CA3130457A CA3130457A CA3130457A1 CA 3130457 A1 CA3130457 A1 CA 3130457A1 CA 3130457 A CA3130457 A CA 3130457A CA 3130457 A CA3130457 A CA 3130457A CA 3130457 A1 CA3130457 A1 CA 3130457A1
Authority
CA
Canada
Prior art keywords
formulation
fatty acid
polysorbate
particles
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3130457A
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English (en)
French (fr)
Inventor
Dorothy KIM
Michael Marlow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Regeneron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Publication of CA3130457A1 publication Critical patent/CA3130457A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CA3130457A 2019-03-05 2020-03-03 Human serum albumin in formulations Pending CA3130457A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962813843P 2019-03-05 2019-03-05
US62/813,843 2019-03-05
PCT/US2020/020752 WO2020180850A1 (en) 2019-03-05 2020-03-03 Human serum albumin in formulations

Publications (1)

Publication Number Publication Date
CA3130457A1 true CA3130457A1 (en) 2020-09-10

Family

ID=70190088

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3130457A Pending CA3130457A1 (en) 2019-03-05 2020-03-03 Human serum albumin in formulations

Country Status (13)

Country Link
US (2) US11241499B2 (https=)
EP (1) EP3934620A1 (https=)
JP (2) JP7561748B2 (https=)
CN (1) CN113543811A (https=)
AU (2) AU2020232683B2 (https=)
BR (1) BR112021015790A2 (https=)
CA (1) CA3130457A1 (https=)
EA (1) EA202192422A1 (https=)
IL (2) IL321704A (https=)
MX (1) MX2021010558A (https=)
SG (1) SG11202109004TA (https=)
WO (1) WO2020180850A1 (https=)
ZA (1) ZA202106012B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022104388A3 (en) * 2020-11-16 2022-06-30 W. L. Gore & Associates, Inc. Formulations, methods, and pre-filled injection devices without fatty acid particles

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202192422A1 (ru) 2019-03-05 2021-12-09 Ридженерон Фармасьютикалз, Инк. Человеческий сывороточный альбумин в составах
KR20240021921A (ko) * 2021-06-14 2024-02-19 리제너론 파아마슈티컬스, 인크. 초고감도 비추출 지방산 정량화 방법을 사용한 제약 제형 중 폴리소르베이트 가수분해 모니터링

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US11241499B2 (en) 2022-02-08
US20200282063A1 (en) 2020-09-10
WO2020180850A1 (en) 2020-09-10
IL285938B1 (en) 2025-07-01
CN113543811A (zh) 2021-10-22
JP2022523962A (ja) 2022-04-27
JP7561748B2 (ja) 2024-10-04
US20220118097A1 (en) 2022-04-21
IL285938A (en) 2021-10-31
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MX2021010558A (es) 2021-10-13
US12594337B2 (en) 2026-04-07
ZA202106012B (en) 2025-04-30
EA202192422A1 (ru) 2021-12-09
IL321704A (en) 2025-08-01
EP3934620A1 (en) 2022-01-12
KR20210135543A (ko) 2021-11-15
BR112021015790A2 (pt) 2021-10-05
AU2020232683A1 (en) 2021-09-02

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