CN1134538C - Fy7聚合酶 - Google Patents

Fy7聚合酶 Download PDF

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Publication number
CN1134538C
CN1134538C CNB998098124A CN99809812A CN1134538C CN 1134538 C CN1134538 C CN 1134538C CN B998098124 A CNB998098124 A CN B998098124A CN 99809812 A CN99809812 A CN 99809812A CN 1134538 C CN1134538 C CN 1134538C
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CN
China
Prior art keywords
dna
polymerase
dna polymerase
sequencing
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998098124A
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English (en)
Chinese (zh)
Other versions
CN1313893A (zh
Inventor
���廪
M·达维斯
C·W·福勒
J·A·马莫尼
L·黄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
Amersham Bioscience AB
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Publication date
Application filed by Amersham Bioscience AB filed Critical Amersham Bioscience AB
Publication of CN1313893A publication Critical patent/CN1313893A/zh
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Publication of CN1134538C publication Critical patent/CN1134538C/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
CNB998098124A 1998-06-17 1999-06-17 Fy7聚合酶 Expired - Fee Related CN1134538C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8955698P 1998-06-17 1998-06-17
US60/089,556 1998-06-17

Publications (2)

Publication Number Publication Date
CN1313893A CN1313893A (zh) 2001-09-19
CN1134538C true CN1134538C (zh) 2004-01-14

Family

ID=22218300

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998098124A Expired - Fee Related CN1134538C (zh) 1998-06-17 1999-06-17 Fy7聚合酶

Country Status (9)

Country Link
US (1) US6479267B1 (enExample)
EP (1) EP1086209B1 (enExample)
JP (1) JP4349545B2 (enExample)
CN (1) CN1134538C (enExample)
AT (1) ATE371022T1 (enExample)
AU (1) AU768993B2 (enExample)
CA (1) CA2330735C (enExample)
DE (1) DE69936919T2 (enExample)
WO (1) WO1999065938A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
CA2440754A1 (en) 2001-03-12 2002-09-19 Stephen Quake Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension
EP1404824A2 (en) 2001-07-06 2004-04-07 Amersham Biosciences Corp. Novel dna polymerases having amino acid substitutions and homologs thereof
AU2002347981A1 (en) * 2001-11-07 2003-05-19 Applera Corporation Universal nucleotides for nucleic acid analysis
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
DE602005020421D1 (de) 2004-02-19 2010-05-20 Helicos Biosciences Corp Verfahren zur analyse von polynukleotidsequenzen
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
DE602005027700D1 (de) 2004-05-25 2011-06-09 Helicos Biosciences Corp Verfahren zur nukleinsäureimmobilisierung
DE602005020011D1 (de) * 2004-06-10 2010-04-29 Ge Healthcare Bio Sciences Verfahren zur nukleinsäureanalyse
JP2008522628A (ja) * 2004-12-11 2008-07-03 サイトジェニックス， インコーポレイテッド 高品質核酸のセルフリー生合成及びその使用
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
EP3447141B1 (en) 2013-03-18 2020-08-05 PreAnalytiX GmbH Stabilisation of biological samples
GB201721053D0 (en) * 2017-12-15 2018-01-31 Univ I Tromsø - Norges Arktiske Univ DNA polymerases
CN110093410A (zh) * 2019-05-21 2019-08-06 通用生物系统（安徽）有限公司 一种dna测序反应试剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795762A (en) 1986-08-22 1998-08-18 Roche Molecular Systems, Inc. 5' to 3' exonuclease mutations of thermostable DNA polymerases
US5618711A (en) 1986-08-22 1997-04-08 Hoffmann-La Roche Inc. Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
JP2531246B2 (ja) * 1988-08-26 1996-09-04 東洋紡績株式会社 耐熱性ｄｎａポリメラ―ゼおよびその製法
SG46627A1 (en) 1989-12-22 1998-02-20 Hoffmann La Roche Recombinant expression vectors and purification methods for thermus thermophilus dna polymerase
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5593840A (en) 1993-01-27 1997-01-14 Oncor, Inc. Amplification of nucleic acid sequences
US5610066A (en) 1993-12-10 1997-03-11 Amersham Life Science, Inc. Nucleic acid modifying proteins from Pyrococcus furiosus
WO1995030756A1 (en) 1994-04-18 1995-11-16 United States Biochemical Corporation Thermostable alkaline phosphatase of thermus thermophilus
WO1996038568A1 (en) * 1995-05-31 1996-12-05 Amersham Life Science, Inc. Thermostable dna polymerases
WO1997009451A1 (en) * 1995-09-08 1997-03-13 Life Technologies, Inc. Cloned dna polymerases from thermotoga and mutants thereof
DE69613856T2 (de) 1995-12-15 2002-04-04 Amersham Pharmacia Biotech Inc., Piscataway Thermostabile dna polymerase aus thermoanaerobacter thermohydrosulfuricus und davon abgeleitete mutierte enzyme mit entfernter exonukleaseaktivität
US6294325B1 (en) 1996-07-05 2001-09-25 The Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of thermostable multi genes and proteins and uses thereof

Also Published As

Publication number Publication date
DE69936919D1 (en) 2007-10-04
WO1999065938A9 (en) 2000-06-08
DE69936919T2 (de) 2008-05-15
ATE371022T1 (de) 2007-09-15
JP2002517997A (ja) 2002-06-25
EP1086209A2 (en) 2001-03-28
CA2330735A1 (en) 1999-12-23
WO1999065938A3 (en) 2000-04-06
AU4575799A (en) 2000-01-05
CN1313893A (zh) 2001-09-19
EP1086209B1 (en) 2007-08-22
US6479267B1 (en) 2002-11-12
CA2330735C (en) 2010-05-11
WO1999065938A2 (en) 1999-12-23
AU768993B2 (en) 2004-01-15
JP4349545B2 (ja) 2009-10-21

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C56 Change in the name or address of the patentee

Owner name: GE HEALTHCARE AS,BIOSCIENCES CORP.

Free format text: FORMER NAME OR ADDRESS: AMERSHAM PHARMACIA BIOTECH AB

CP01 Change in the name or title of a patent holder

Address after: New jersey, USA

Patentee after: GE HEALTHCARE BIO-SCIENCES Corp.

Address before: New jersey, USA

Patentee before: Amersham Biosciences AB

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20040114

Termination date: 20180617