ATE371022T1 - Fy7 polymerase - Google Patents

Fy7 polymerase

Info

Publication number
ATE371022T1
ATE371022T1 AT99928766T AT99928766T ATE371022T1 AT E371022 T1 ATE371022 T1 AT E371022T1 AT 99928766 T AT99928766 T AT 99928766T AT 99928766 T AT99928766 T AT 99928766T AT E371022 T1 ATE371022 T1 AT E371022T1
Authority
AT
Austria
Prior art keywords
polymerase
dna
activity
nucleic acid
recombinant
Prior art date
Application number
AT99928766T
Other languages
German (de)
English (en)
Inventor
Maria Davis
Carl W Fuller
Joseph A Mamone
Lin Huang
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Application granted granted Critical
Publication of ATE371022T1 publication Critical patent/ATE371022T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
AT99928766T 1998-06-17 1999-06-17 Fy7 polymerase ATE371022T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8955698P 1998-06-17 1998-06-17

Publications (1)

Publication Number Publication Date
ATE371022T1 true ATE371022T1 (de) 2007-09-15

Family

ID=22218300

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99928766T ATE371022T1 (de) 1998-06-17 1999-06-17 Fy7 polymerase

Country Status (9)

Country Link
US (1) US6479267B1 (enExample)
EP (1) EP1086209B1 (enExample)
JP (1) JP4349545B2 (enExample)
CN (1) CN1134538C (enExample)
AT (1) ATE371022T1 (enExample)
AU (1) AU768993B2 (enExample)
CA (1) CA2330735C (enExample)
DE (1) DE69936919T2 (enExample)
WO (1) WO1999065938A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
CA2440754A1 (en) 2001-03-12 2002-09-19 Stephen Quake Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension
EP1404824A2 (en) 2001-07-06 2004-04-07 Amersham Biosciences Corp. Novel dna polymerases having amino acid substitutions and homologs thereof
AU2002347981A1 (en) * 2001-11-07 2003-05-19 Applera Corporation Universal nucleotides for nucleic acid analysis
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
DE602005020421D1 (de) 2004-02-19 2010-05-20 Helicos Biosciences Corp Verfahren zur analyse von polynukleotidsequenzen
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
DE602005027700D1 (de) 2004-05-25 2011-06-09 Helicos Biosciences Corp Verfahren zur nukleinsäureimmobilisierung
DE602005020011D1 (de) * 2004-06-10 2010-04-29 Ge Healthcare Bio Sciences Verfahren zur nukleinsäureanalyse
JP2008522628A (ja) * 2004-12-11 2008-07-03 サイトジェニックス， インコーポレイテッド 高品質核酸のセルフリー生合成及びその使用
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
EP3447141B1 (en) 2013-03-18 2020-08-05 PreAnalytiX GmbH Stabilisation of biological samples
GB201721053D0 (en) * 2017-12-15 2018-01-31 Univ I Tromsø - Norges Arktiske Univ DNA polymerases
CN110093410A (zh) * 2019-05-21 2019-08-06 通用生物系统（安徽）有限公司 一种dna测序反应试剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795762A (en) 1986-08-22 1998-08-18 Roche Molecular Systems, Inc. 5' to 3' exonuclease mutations of thermostable DNA polymerases
US5618711A (en) 1986-08-22 1997-04-08 Hoffmann-La Roche Inc. Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
JP2531246B2 (ja) * 1988-08-26 1996-09-04 東洋紡績株式会社 耐熱性ｄｎａポリメラ―ゼおよびその製法
SG46627A1 (en) 1989-12-22 1998-02-20 Hoffmann La Roche Recombinant expression vectors and purification methods for thermus thermophilus dna polymerase
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5593840A (en) 1993-01-27 1997-01-14 Oncor, Inc. Amplification of nucleic acid sequences
US5610066A (en) 1993-12-10 1997-03-11 Amersham Life Science, Inc. Nucleic acid modifying proteins from Pyrococcus furiosus
WO1995030756A1 (en) 1994-04-18 1995-11-16 United States Biochemical Corporation Thermostable alkaline phosphatase of thermus thermophilus
WO1996038568A1 (en) * 1995-05-31 1996-12-05 Amersham Life Science, Inc. Thermostable dna polymerases
WO1997009451A1 (en) * 1995-09-08 1997-03-13 Life Technologies, Inc. Cloned dna polymerases from thermotoga and mutants thereof
DE69613856T2 (de) 1995-12-15 2002-04-04 Amersham Pharmacia Biotech Inc., Piscataway Thermostabile dna polymerase aus thermoanaerobacter thermohydrosulfuricus und davon abgeleitete mutierte enzyme mit entfernter exonukleaseaktivität
US6294325B1 (en) 1996-07-05 2001-09-25 The Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of thermostable multi genes and proteins and uses thereof

Also Published As

Publication number Publication date
DE69936919D1 (en) 2007-10-04
WO1999065938A9 (en) 2000-06-08
DE69936919T2 (de) 2008-05-15
JP2002517997A (ja) 2002-06-25
EP1086209A2 (en) 2001-03-28
CN1134538C (zh) 2004-01-14
CA2330735A1 (en) 1999-12-23
WO1999065938A3 (en) 2000-04-06
AU4575799A (en) 2000-01-05
CN1313893A (zh) 2001-09-19
EP1086209B1 (en) 2007-08-22
US6479267B1 (en) 2002-11-12
CA2330735C (en) 2010-05-11
WO1999065938A2 (en) 1999-12-23
AU768993B2 (en) 2004-01-15
JP4349545B2 (ja) 2009-10-21

Similar Documents

Publication Publication Date Title
ATE371022T1 (de) Fy7 polymerase
BG100188A (bg) Ензими за секвениране на днк
ATE302279T1 (de) Kälteempfindliche dna-polymerasemutanten
ATE466948T1 (de) Dns-basiertes transposon-system für die einführung von nucleinsäure in die dns einer zelle
DE69133204D1 (en) Gereinigtes thermostabiles nukleinsäure-polymeraseenzym aus thermotoga maritima
WO1999020766A3 (en) NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
GB2363795A (en) Process for nucleic acid purification using silicon carbide
ATE181106T1 (de) Mutationen in der 5'-3'-exonukleaseaktivität thermostabiler dna-polymerasen
DE69426400D1 (de) Thermostable Nukleinsäure Polymerase
ATE557084T1 (de) Modifizierte dna-polymerasen zur verbesserten inkorporation von nukleotidanaloga
ATE418563T1 (de) Nik proteine, nukleinsäure sowie verfahren
IL115643A0 (en) Dna polymerase having modified nucleotide binding site for dna sequencing
EP1005540A4 (en) IKK-BETA PROTEINS, NUCLEIC ACIDS AND METHODS
EP0973794A4 (en) NETRIN RECEPTORS
ATE211174T1 (de) Thymidin-kinase-mutanten
BR0003943A (pt) Sequências de nucleotìdeo que codificam para o gene thre e processo para a produção enzimática de l-treonina usando bactérias corineforma
CA2281895A1 (en) Ikb kinases
EP0754765A3 (en) DNA sequencing and DNA terminators
AU1204600A (en) Systems and methods for sequencing by hybridization
DK1235916T3 (da) Isolerede polynukleotider med et formindsket indhold af 5'CpG3' epigenitiske kontrolmotiver og anvendelser deraf
ATE463572T1 (de) Rekombinanter faktor viii mit erhöhter spezifischer aktivität
DE60130465D1 (de) Mutierte muskelspezifische enhancer
ATE408621T1 (de) Dna moleküle
WO2003054181A3 (en) Nucleic acid labeling by thermoanaerobacter thermohydrosulfuricus dna polymerase i variants
Shankar et al. MhaAI, a novel isoschizomer of PstI from Mycobacterium habana recognizing 5'-CTGCA/G-3'

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties