CN113167772A - 具有多个色谱仪的分析装置及其控制方法 - Google Patents

具有多个色谱仪的分析装置及其控制方法 Download PDF

Info

Publication number
CN113167772A
CN113167772A CN201980076460.3A CN201980076460A CN113167772A CN 113167772 A CN113167772 A CN 113167772A CN 201980076460 A CN201980076460 A CN 201980076460A CN 113167772 A CN113167772 A CN 113167772A
Authority
CN
China
Prior art keywords
chromatographic separation
column
separation
unit
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201980076460.3A
Other languages
English (en)
Chinese (zh)
Inventor
绪方泉
杉目和之
野上真
秋枝大介
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi High Tech Corp
Original Assignee
Hitachi High Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi High Technologies Corp filed Critical Hitachi High Technologies Corp
Publication of CN113167772A publication Critical patent/CN113167772A/zh
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/86Signal analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/24Automatic injection systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/30Control of physical parameters of the fluid carrier of temperature
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • G01N30/46Flow patterns using more than one column
    • G01N30/466Flow patterns using more than one column with separation columns in parallel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6034Construction of the column joining multiple columns
    • G01N30/6043Construction of the column joining multiple columns in parallel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N2030/022Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027Liquid chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/52Physical parameters
    • G01N30/54Temperature
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
CN201980076460.3A 2018-11-20 2019-11-20 具有多个色谱仪的分析装置及其控制方法 Withdrawn CN113167772A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018-217175 2018-11-20
JP2018217175 2018-11-20
PCT/JP2019/045363 WO2020105661A1 (ja) 2018-11-20 2019-11-20 複数のクロマトグラフを有する分析装置及びその制御方法

Publications (1)

Publication Number Publication Date
CN113167772A true CN113167772A (zh) 2021-07-23

Family

ID=70773137

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980076460.3A Withdrawn CN113167772A (zh) 2018-11-20 2019-11-20 具有多个色谱仪的分析装置及其控制方法

Country Status (5)

Country Link
US (1) US20220011280A1 (https=)
EP (1) EP3885764A4 (https=)
JP (1) JPWO2020105661A1 (https=)
CN (1) CN113167772A (https=)
WO (1) WO2020105661A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230136667A1 (en) * 2021-10-29 2023-05-04 Shimadzu Corporation Method of cleaning liquid chromatographic system and liquid chromatographic system
CN117310061A (zh) * 2023-10-27 2023-12-29 广州智达实验室科技有限公司 样品进样的控制方法、装置、计算机设备和存储介质
CN117929610A (zh) * 2023-06-16 2024-04-26 常州三泰科技有限公司 一种液相色谱仪系统控制方法及装置
US12259372B2 (en) 2021-10-29 2025-03-25 Shimadzu Corporation Method of cleaning liquid chromatographic system and liquid chromatographic system
US12292423B2 (en) 2021-10-29 2025-05-06 Shimadzu Corporation Liquid chromatographic system and method of cleaning the same, and computer readable medium

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113396328B (zh) * 2019-02-22 2024-09-10 株式会社日立高新技术 分析装置
JP2024081805A (ja) * 2021-03-03 2024-06-19 株式会社日立ハイテク 液体クロマトグラフ質量分析装置の制御方法、および液体クロマトグラフ質量分析装置
WO2022190605A1 (ja) * 2021-03-08 2022-09-15 株式会社日立ハイテク 自動分析装置の制御方法
CN120586446B (zh) * 2025-08-07 2025-10-21 中粮生化(成都)有限公司 一种顺序式模拟移动床色谱分离系统及其独立反洗方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06324027A (ja) * 1993-05-12 1994-11-25 Hitachi Ltd 自動液体クロマトグラフ
JP2001208738A (ja) * 2000-01-28 2001-08-03 Sumitomo Chem Co Ltd 分析条件選択方法および高速液体クロマトグラフィ装置
JP2002014084A (ja) * 2000-06-30 2002-01-18 Shimadzu Corp 液体クロマトグラフ
CN103370616A (zh) * 2010-10-29 2013-10-23 恩姆菲舍尔科技公司 用于样品制备和分析的自动化系统
US20180284079A1 (en) * 2017-03-30 2018-10-04 Shimadzu Corporation Liquid chromatograph

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3841059A (en) * 1972-09-25 1974-10-15 W Mccabe Compressed and thermostated air regulated gas liquid chromatography oven with simultaneously operated multiple chromatography columns
JP2800509B2 (ja) * 1990-11-30 1998-09-21 株式会社日立製作所 液体クロマトグラフ装置
AU2986400A (en) * 1999-02-08 2000-08-25 Admetric Biochem Inc. Chromatographic system with pre-detector eluent switching
JP3898374B2 (ja) * 1999-04-16 2007-03-28 株式会社島津製作所 自動分析装置
EP1269171B1 (en) * 2000-03-07 2006-05-31 Northeastern University Parallel array of independent thermostats for column separations
US6635173B2 (en) * 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
US7261812B1 (en) * 2002-02-13 2007-08-28 Nanostream, Inc. Multi-column separation devices and methods
US7132650B1 (en) * 2003-09-26 2006-11-07 Nanostream, Inc. High throughput multi-dimensional sample analysis
US7214320B1 (en) * 2002-08-08 2007-05-08 Nanostream, Inc. Systems and methods for high throughput sample analysis
US20050048669A1 (en) * 2003-08-26 2005-03-03 Nanostream, Inc. Gasketless microfluidic device interface
WO2004040295A1 (en) * 2002-10-31 2004-05-13 Nanostream, Inc. Parallel detection chromatography systems
US6936167B2 (en) * 2002-10-31 2005-08-30 Nanostream, Inc. System and method for performing multiple parallel chromatographic separations
US6987263B2 (en) * 2002-12-13 2006-01-17 Nanostream, Inc. High throughput systems and methods for parallel sample analysis
JP3816883B2 (ja) * 2003-03-06 2006-08-30 株式会社日立ハイテクノロジーズ 液体クロマトグラフ質量分析装置
WO2004101151A1 (en) * 2003-05-08 2004-11-25 Nanostream, Inc. Sample preparation for parallel chromatography
US20050032238A1 (en) * 2003-08-07 2005-02-10 Nanostream, Inc. Vented microfluidic separation devices and methods
FI117179B (fi) * 2004-01-23 2006-07-14 Environics Oy Kaasukromatografi
JP2006125856A (ja) * 2004-10-26 2006-05-18 Sumitomo Chemical Co Ltd 液体クロマトグラフィー装置
JP6314989B2 (ja) * 2013-09-25 2018-04-25 株式会社島津製作所 ガスクロマトグラフ質量分析装置
JP6331485B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ及び液体クロマトグラフ分析方法
CN107110830B (zh) * 2015-01-26 2019-11-22 株式会社岛津制作所 气相色谱仪
DE112016006847T5 (de) * 2016-06-16 2019-02-07 Hitachi High-Technologies Corporation Chromatographie-Massenanalysevorrichtung und Steuerverfahren
EP3523646B1 (en) * 2016-10-04 2023-05-10 The Regents of The University of Michigan Multi-channel multi-dimensional comprehensive gas chromatography
JP7035951B2 (ja) * 2018-10-16 2022-03-15 株式会社島津製作所 前処理装置およびこれを備えた分析システム
US12130267B2 (en) * 2018-11-28 2024-10-29 Shimadzu Corporation Analyzing method for azo compound
CN113396328B (zh) * 2019-02-22 2024-09-10 株式会社日立高新技术 分析装置
JP7388206B2 (ja) * 2020-01-22 2023-11-29 株式会社島津製作所 液体クロマトグラフおよび分析方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06324027A (ja) * 1993-05-12 1994-11-25 Hitachi Ltd 自動液体クロマトグラフ
JP2001208738A (ja) * 2000-01-28 2001-08-03 Sumitomo Chem Co Ltd 分析条件選択方法および高速液体クロマトグラフィ装置
JP2002014084A (ja) * 2000-06-30 2002-01-18 Shimadzu Corp 液体クロマトグラフ
CN103370616A (zh) * 2010-10-29 2013-10-23 恩姆菲舍尔科技公司 用于样品制备和分析的自动化系统
US20180284079A1 (en) * 2017-03-30 2018-10-04 Shimadzu Corporation Liquid chromatograph

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230136667A1 (en) * 2021-10-29 2023-05-04 Shimadzu Corporation Method of cleaning liquid chromatographic system and liquid chromatographic system
CN116060344A (zh) * 2021-10-29 2023-05-05 株式会社岛津制作所 液体层析系统的清洗方法以及液体层析系统
US12259372B2 (en) 2021-10-29 2025-03-25 Shimadzu Corporation Method of cleaning liquid chromatographic system and liquid chromatographic system
US12287314B2 (en) * 2021-10-29 2025-04-29 Shimadzu Corporation Method of cleaning liquid chromatographic system and liquid chromatographic system
CN116060344B (zh) * 2021-10-29 2025-04-29 株式会社岛津制作所 液体层析系统的清洗方法以及液体层析系统
US12292423B2 (en) 2021-10-29 2025-05-06 Shimadzu Corporation Liquid chromatographic system and method of cleaning the same, and computer readable medium
CN117929610A (zh) * 2023-06-16 2024-04-26 常州三泰科技有限公司 一种液相色谱仪系统控制方法及装置
WO2024255529A1 (zh) * 2023-06-16 2024-12-19 常州三泰科技有限公司 一种液相色谱仪系统控制方法及装置
CN117310061A (zh) * 2023-10-27 2023-12-29 广州智达实验室科技有限公司 样品进样的控制方法、装置、计算机设备和存储介质

Also Published As

Publication number Publication date
WO2020105661A1 (ja) 2020-05-28
US20220011280A1 (en) 2022-01-13
EP3885764A4 (en) 2022-08-17
EP3885764A1 (en) 2021-09-29
JPWO2020105661A1 (ja) 2021-09-30

Similar Documents

Publication Publication Date Title
CN113167772A (zh) 具有多个色谱仪的分析装置及其控制方法
JP6790963B2 (ja) 液体クロマトグラフ
JP7224434B2 (ja) 分析装置
CN111868517B (zh) 具有多个色谱仪的分析装置
US20110306146A1 (en) Parallel Screening Supercritical Fluid Chromatography
CN104897788B (zh) 液相色谱仪和液相色谱仪分析方法
US10890566B2 (en) Automatic analysis control device and program
JP7574321B2 (ja) 自動分析装置の制御方法
CN104897822B (zh) 液相色谱仪控制系统和液相色谱仪控制方法
WO2021209373A1 (en) Analytical system and method including switching between liquid chromatography fluidic streams
JP7262472B2 (ja) 液体クロマトグラフを有する分析装置および液体クロマトグラフの分析方法
WO2015063886A1 (ja) 液体クロマトグラフ装置
WO2017122261A1 (ja) 液体クロマトグラフ分析装置
EP3992627B1 (en) Liquid chromatography - stream equivalence by single stream calibration
JPWO2018051610A1 (ja) 液体クロマトグラフ
JP5202272B2 (ja) 液体クロマトグラフ、液体クロマトグラフ用送液ポンプおよび液体クロマトグラフの洗浄方法
JP7492646B2 (ja) 自動分析装置の制御方法
EP4270000B1 (en) Liquid chromatograph control method and liquid chromatograph
JP2022171634A (ja) カラムのバックフラッシュを有するlcシステムおよび方法
JP2018197669A (ja) ガスクロマトグラフ装置
JP2021110548A (ja) 分析装置及び分析装置の使用方法
WO2026078978A1 (ja) 自動分析装置
JP2007121192A (ja) 液体クロマトグラフ装置

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20210723

WW01 Invention patent application withdrawn after publication