CN113164448A - 作为il-17的小分子调节剂的氨基酸苯胺类化合物 - Google Patents

作为il-17的小分子调节剂的氨基酸苯胺类化合物 Download PDF

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CN113164448A
CN113164448A CN201980081538.0A CN201980081538A CN113164448A CN 113164448 A CN113164448 A CN 113164448A CN 201980081538 A CN201980081538 A CN 201980081538A CN 113164448 A CN113164448 A CN 113164448A
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pyrazol
preparation
compound
ethyl
alkyl
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K·N·达克
梁锡富
M·拉森
M·安德鲁斯
A·S·杰西曼
M·N·伯哈德特
P·S·约翰逊
P·安德森
L·约尔根森
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Leo Pharma AS
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    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/4164—1,3-Diazoles
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CN201980081538.0A 2018-12-19 2019-12-19 作为il-17的小分子调节剂的氨基酸苯胺类化合物 Pending CN113164448A (zh)

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EP18214002 2018-12-19
EP18214002.0 2018-12-19
EP19187352.0 2019-07-19
EP19187352 2019-07-19
PCT/EP2019/086239 WO2020127685A1 (en) 2018-12-19 2019-12-19 Amino-acid anilides as small molecule modulators of il-17

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CN113929598A (zh) * 2021-11-24 2022-01-14 上海吉奉生物科技有限公司 一种（s）-2-叔丁氧羰基氨基-3-（4,4-二氟环己基）丙酸的合成方法
CN116547275A (zh) * 2020-05-27 2023-08-04 赛诺菲 Il-17a调节剂
CN116568676A (zh) * 2020-05-27 2023-08-08 赛诺菲 Il-17a调节剂
CN116840382A (zh) * 2023-07-13 2023-10-03 北京市农产品质量安全中心 同时检测水产品中11种药物及代谢物残留量的方法
CN117279889A (zh) * 2022-04-28 2023-12-22 深圳湾实验室 经取代的氟硫酸盐及其用途
CN119192167A (zh) * 2024-11-28 2024-12-27 英矽智能科技(上海)有限公司 一类抑制il-17的化合物

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WO2017087885A1 (en) 2015-11-19 2017-05-26 Dana-Farber Cancer Institute, Inc. Methods of identifying compounds that interfere with erg-driven misguidance of baf complexes in tmprss2-erg driven prostate cancers
US11497752B2 (en) 2018-01-30 2022-11-15 Foghorn Therapeutics Inc. Compounds and uses thereof
AU2019224354A1 (en) * 2018-02-22 2020-10-08 Nippon Zoki Pharmaceutical Co., Ltd. IL-17a activity inhibitor and use thereof
WO2020081588A1 (en) 2018-10-17 2020-04-23 Dana-Farber Cancer Institute, Inc. Swi/snf family chromatin remodeling complexes and uses thereof
TWI752400B (zh) 2019-01-07 2022-01-11 美商美國禮來大藥廠 Il-17a抑制劑
CN113645971B (zh) * 2019-01-29 2024-10-18 福宏治疗公司 化合物及其用途
US12509453B2 (en) 2019-01-29 2025-12-30 Foghorn Therapeutics Inc. BRM/BRG1 inhibitors and uses thereof
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