CN113015906A - 一种凝血分析仪及其纤维蛋白原浓度检测方法 - Google Patents
一种凝血分析仪及其纤维蛋白原浓度检测方法 Download PDFInfo
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Abstract
一种凝血分析仪及其纤维蛋白原浓度检测方法,在PT检测完成后,重新驱动磁珠在凝固后的被测试样中运动,通过检测磁珠的运动情况确定样本中纤维蛋白原浓度,从而实现了基于磁珠法的检测纤维蛋白原浓度的PT衍算法。
Description
PCT国内申请,说明书已公开。
Claims (27)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
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CNPCT/CN2018/124787 | 2018-12-28 | ||
PCT/CN2018/124787 WO2020133188A1 (zh) | 2018-12-28 | 2018-12-28 | 一种凝血分析仪及其纤维蛋白原浓度检测方法 |
PCT/CN2019/084127 WO2020133842A1 (zh) | 2018-12-28 | 2019-04-24 | 一种凝血分析仪及其纤维蛋白原浓度检测方法 |
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CN113015906A true CN113015906A (zh) | 2021-06-22 |
CN113015906B CN113015906B (zh) | 2023-10-03 |
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Cited By (1)
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CN113484527A (zh) * | 2021-06-23 | 2021-10-08 | 江苏鸿恩医疗器械有限公司 | 一种基于凝血分析仪用试剂的双对数定标方法 |
Families Citing this family (1)
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CN115078702A (zh) * | 2021-03-12 | 2022-09-20 | 重庆南方数控设备股份有限公司 | 一种基于磁珠的血栓弹力图检测装置及方法 |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06141895A (ja) * | 1992-11-12 | 1994-05-24 | Tokuyama Soda Co Ltd | フィブリノゲンの定量方法 |
JPH06209794A (ja) * | 1993-01-19 | 1994-08-02 | Tokuyama Soda Co Ltd | フィブリノゲンの定量方法 |
CN1936580A (zh) * | 2005-09-22 | 2007-03-28 | 天津市美德太平洋精密仪器制造有限公司 | 利用磁珠法检测全血标本凝血项目的方法 |
CN101308149A (zh) * | 2008-07-16 | 2008-11-19 | 上海凯颐医疗仪器有限公司 | 血液凝固时间测量装置及其测量方法 |
US20140308680A1 (en) * | 2011-10-14 | 2014-10-16 | Koninklijke Philips N.V. | Method for detection of coagulation activity and biomarkers |
CN105548582A (zh) * | 2014-10-31 | 2016-05-04 | 陕西盛迈石油有限公司 | 一种凝血分析仪 |
US20160291008A1 (en) * | 2013-11-15 | 2016-10-06 | President And Fellows Of Harvard College | Methods and assays for factor viii activity |
CN107003297A (zh) * | 2014-12-15 | 2017-08-01 | 斯塔戈诊断公司 | 用于确定血液样品的凝结时间的方法和设备,以及反应容器 |
CN108020675A (zh) * | 2017-11-30 | 2018-05-11 | 迈克医疗电子有限公司 | 一种凝血时间测定方法、装置及系统 |
CN109085368A (zh) * | 2018-08-14 | 2018-12-25 | 王振华 | 一种凝血分析装置 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5110727A (en) * | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
US6524861B1 (en) * | 1999-01-22 | 2003-02-25 | Medical Laboratory Automation, Inc. | Blood coagulation analyzer |
CN102262090B (zh) * | 2010-05-24 | 2012-09-12 | 北京普利生仪器有限公司 | 一种血小板聚集性和凝血因子的测定方法及设备 |
CN102565317B (zh) * | 2010-12-24 | 2013-08-14 | 北京普利生仪器有限公司 | 一种凝血因子和d-二聚体的测定方法 |
CN203148811U (zh) * | 2013-03-27 | 2013-08-21 | 山西亚森实业有限公司 | 血凝分析仪 |
CN205157563U (zh) * | 2015-12-10 | 2016-04-13 | 吕铝淼 | 一种新型血凝杯 |
CN207636616U (zh) * | 2017-07-27 | 2018-07-20 | 深圳传世生物医疗有限公司 | 凝血分析仪 |
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2018
- 2018-12-28 WO PCT/CN2018/124787 patent/WO2020133188A1/zh active Application Filing
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2019
- 2019-04-24 WO PCT/CN2019/084127 patent/WO2020133842A1/zh active Application Filing
- 2019-04-24 CN CN201980073589.9A patent/CN113015906B/zh active Active
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06141895A (ja) * | 1992-11-12 | 1994-05-24 | Tokuyama Soda Co Ltd | フィブリノゲンの定量方法 |
JPH06209794A (ja) * | 1993-01-19 | 1994-08-02 | Tokuyama Soda Co Ltd | フィブリノゲンの定量方法 |
CN1936580A (zh) * | 2005-09-22 | 2007-03-28 | 天津市美德太平洋精密仪器制造有限公司 | 利用磁珠法检测全血标本凝血项目的方法 |
CN101308149A (zh) * | 2008-07-16 | 2008-11-19 | 上海凯颐医疗仪器有限公司 | 血液凝固时间测量装置及其测量方法 |
US20140308680A1 (en) * | 2011-10-14 | 2014-10-16 | Koninklijke Philips N.V. | Method for detection of coagulation activity and biomarkers |
US20160291008A1 (en) * | 2013-11-15 | 2016-10-06 | President And Fellows Of Harvard College | Methods and assays for factor viii activity |
CN105548582A (zh) * | 2014-10-31 | 2016-05-04 | 陕西盛迈石油有限公司 | 一种凝血分析仪 |
CN107003297A (zh) * | 2014-12-15 | 2017-08-01 | 斯塔戈诊断公司 | 用于确定血液样品的凝结时间的方法和设备,以及反应容器 |
CN108020675A (zh) * | 2017-11-30 | 2018-05-11 | 迈克医疗电子有限公司 | 一种凝血时间测定方法、装置及系统 |
CN109085368A (zh) * | 2018-08-14 | 2018-12-25 | 王振华 | 一种凝血分析装置 |
Non-Patent Citations (3)
Title |
---|
LEANNE F. HARRIS 等: "Coagulation monitoring devices: Past, present, and future at the point of care", 《TRENDS IN ANALYTICAL CHEMISTRY》 * |
LIANQING ZHU等: "Dual magnetic circuit magnetic bead coagulation test method", 《PROCEEDINGS OF SPIE》 * |
蒙长虹 等: "磁珠法测定纤维蛋白原的局限性探讨", 《检验医学》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113484527A (zh) * | 2021-06-23 | 2021-10-08 | 江苏鸿恩医疗器械有限公司 | 一种基于凝血分析仪用试剂的双对数定标方法 |
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WO2020133842A1 (zh) | 2020-07-02 |
CN113015906B (zh) | 2023-10-03 |
WO2020133188A1 (zh) | 2020-07-02 |
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