CN112823666A - 一种同时含叶黄素和蛹虫草醇提物的纳米脂质体及其制备方法 - Google Patents

一种同时含叶黄素和蛹虫草醇提物的纳米脂质体及其制备方法 Download PDF

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Publication number
CN112823666A
CN112823666A CN201911145526.8A CN201911145526A CN112823666A CN 112823666 A CN112823666 A CN 112823666A CN 201911145526 A CN201911145526 A CN 201911145526A CN 112823666 A CN112823666 A CN 112823666A
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Prior art keywords
alcohol extract
cordyceps militaris
lutein
militaris alcohol
liposome
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Pending
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CN201911145526.8A
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Chinese (zh)
Inventor
宋江峰
徐鹏翔
戴竹青
吴彩娥
李大婧
刘春泉
张钟元
王琨
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Jiangsu Academy of Agricultural Sciences
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Jiangsu Academy of Agricultural Sciences
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Priority to CN201911145526.8A priority Critical patent/CN112823666A/zh
Priority to PCT/CN2020/092080 priority patent/WO2021098174A1/fr
Priority to LU101863A priority patent/LU101863B1/en
Publication of CN112823666A publication Critical patent/CN112823666A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A23L31/10Yeasts or derivatives thereof
    • A23L31/15Extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03Organic compounds
    • A23L29/035Organic compounds containing oxygen as heteroatom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03Organic compounds
    • A23L29/05Organic compounds containing phosphorus as heteroatom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/10Foods or foodstuffs containing additives; Preparation or treatment thereof containing emulsifiers
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201911145526.8A 2019-11-21 2019-11-21 一种同时含叶黄素和蛹虫草醇提物的纳米脂质体及其制备方法 Pending CN112823666A (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201911145526.8A CN112823666A (zh) 2019-11-21 2019-11-21 一种同时含叶黄素和蛹虫草醇提物的纳米脂质体及其制备方法
PCT/CN2020/092080 WO2021098174A1 (fr) 2019-11-21 2020-05-25 Nanoliposome contenant de la lutéine et un extrait d'alcool de cordyceps militaris, et son procédé de préparation
LU101863A LU101863B1 (en) 2019-11-21 2020-05-25 Nano-liposome simultaneously containing lutein and cordyceps militaris alcohol extract, and preparation method therefor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911145526.8A CN112823666A (zh) 2019-11-21 2019-11-21 一种同时含叶黄素和蛹虫草醇提物的纳米脂质体及其制备方法

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CN112823666A true CN112823666A (zh) 2021-05-21

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CN (1) CN112823666A (fr)
LU (1) LU101863B1 (fr)
WO (1) WO2021098174A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116473231A (zh) * 2023-03-15 2023-07-25 武汉林宝莱生物科技有限公司 一种蓝莓叶黄素酯纳米脂质体及其制备方法和应用

Citations (9)

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EP0678295A2 (fr) * 1994-04-22 1995-10-25 Ugo Citernesi Procédé de préparation de complexes d'un phospholipide avec une substance active utilisables pour la fabrication de liposomes
CN1294133A (zh) * 2000-11-06 2001-05-09 吉林东北虎药业股份有限公司 虫草素提取工艺及制剂
CN101816632A (zh) * 2010-04-23 2010-09-01 广东药学院 一种复合功能脂质体及其制备方法和应用
CN103689554A (zh) * 2013-12-25 2014-04-02 广州安德健康科技有限公司 一种蛹虫草脂质体的制备方法及其应用
US20150086611A1 (en) * 2013-09-26 2015-03-26 Samsung Electronics Co., Ltd. Liposome including complex of hydrophobic active ingredient and polypeptide and use of the liposome
CN105726482A (zh) * 2016-01-27 2016-07-06 江苏省农业科学院 一种叶黄素纳米脂质体及其制备方法
CN106798725A (zh) * 2015-11-26 2017-06-06 王春梅 一种虫草素纳米脂质体及其制备方法与抗肿瘤活性应用
CN108851072A (zh) * 2018-04-18 2018-11-23 江苏师范大学 一种紫甘薯花青素纳米脂质体及其制备方法
CN110302161A (zh) * 2019-07-08 2019-10-08 大连理工大学 一种复合纳米脂质体及其应用

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CN102793177B (zh) * 2012-09-07 2013-11-27 广州安德生物科技有限公司 一种生物黏附型蛹虫草脂质体及其制备方法
CN107927739A (zh) * 2017-12-26 2018-04-20 北京牧笛生物科技有限公司 一种食品营养强化剂及其制备方法

Patent Citations (9)

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EP0678295A2 (fr) * 1994-04-22 1995-10-25 Ugo Citernesi Procédé de préparation de complexes d'un phospholipide avec une substance active utilisables pour la fabrication de liposomes
CN1294133A (zh) * 2000-11-06 2001-05-09 吉林东北虎药业股份有限公司 虫草素提取工艺及制剂
CN101816632A (zh) * 2010-04-23 2010-09-01 广东药学院 一种复合功能脂质体及其制备方法和应用
US20150086611A1 (en) * 2013-09-26 2015-03-26 Samsung Electronics Co., Ltd. Liposome including complex of hydrophobic active ingredient and polypeptide and use of the liposome
CN103689554A (zh) * 2013-12-25 2014-04-02 广州安德健康科技有限公司 一种蛹虫草脂质体的制备方法及其应用
CN106798725A (zh) * 2015-11-26 2017-06-06 王春梅 一种虫草素纳米脂质体及其制备方法与抗肿瘤活性应用
CN105726482A (zh) * 2016-01-27 2016-07-06 江苏省农业科学院 一种叶黄素纳米脂质体及其制备方法
CN108851072A (zh) * 2018-04-18 2018-11-23 江苏师范大学 一种紫甘薯花青素纳米脂质体及其制备方法
CN110302161A (zh) * 2019-07-08 2019-10-08 大连理工大学 一种复合纳米脂质体及其应用

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阴婷婷等: "中链脂肪酸-VC复合脂质体制备及初步稳定性", 《食品科学》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116473231A (zh) * 2023-03-15 2023-07-25 武汉林宝莱生物科技有限公司 一种蓝莓叶黄素酯纳米脂质体及其制备方法和应用

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LU101863B1 (en) 2021-06-03

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