CN112805567A - 红细胞模拟粒子、其制备方法及含其的质控物或校准物 - Google Patents
红细胞模拟粒子、其制备方法及含其的质控物或校准物 Download PDFInfo
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- CN112805567A CN112805567A CN201880098394.5A CN201880098394A CN112805567A CN 112805567 A CN112805567 A CN 112805567A CN 201880098394 A CN201880098394 A CN 201880098394A CN 112805567 A CN112805567 A CN 112805567A
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- Prior art keywords
- red blood
- erythrocyte
- blood cell
- treatment
- acid
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Images
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
Abstract
一种红细胞模拟粒子、其制备方法及含有该红细胞模拟粒子的质控物或校准物。制备红细胞模拟粒子的方法包括采用pH为5.0～9.0、渗透压为300～800Osm/kg·H2O的红细胞处理液对红细胞进行氧化处理和固定处理，其中，该红细胞处理液含有选自卤素含氧酸盐的至少一种氧化剂和选自醛或酸的至少一种固定剂；和将经该红细胞处理液处理后的红细胞洗涤并悬浮在保存液中。该方法采用环境友好的卤素含氧酸盐作为氧化剂，获得了能够长期稳定保存的且在红细胞检测通道中与天然血液红细胞粒子性质类似的红细胞模拟粒子。
Description
PCT国内申请，说明书已公开。
Claims (20)
- PCT国内申请，权利要求书已公开。
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| PCT/CN2018/123529 WO2020132875A1 (zh) | 2018-12-25 | 2018-12-25 | 红细胞模拟粒子、其制备方法及含其的质控物或校准物 |
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| CN112805567A true CN112805567A (zh) | 2021-05-14 |
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| CN114591906B (zh) * | 2022-05-09 | 2022-09-16 | 深圳市帝迈生物技术有限公司 | 红细胞模拟物、其制备方法及质控物或校准物 |
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| WO2020132875A1 (zh) | 2020-07-02 |
| US20210311080A1 (en) | 2021-10-07 |
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