CN112739338A - β-内酰胺化合物与丙磺舒的组合及其用途 - Google Patents
β-内酰胺化合物与丙磺舒的组合及其用途 Download PDFInfo
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- CN112739338A CN112739338A CN201980052188.5A CN201980052188A CN112739338A CN 112739338 A CN112739338 A CN 112739338A CN 201980052188 A CN201980052188 A CN 201980052188A CN 112739338 A CN112739338 A CN 112739338A
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- lactam compound
- pharmaceutically acceptable
- acceptable salt
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- beta
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Physiology (AREA)
- Psychology (AREA)
- Inorganic Chemistry (AREA)
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- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410957648.1A CN118903120A (zh) | 2018-06-07 | 2019-06-07 | β-内酰胺化合物与丙磺舒的组合及其用途 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862682116P | 2018-06-07 | 2018-06-07 | |
| US62/682116 | 2018-06-07 | ||
| US201962804970P | 2019-02-13 | 2019-02-13 | |
| US62/804970 | 2019-02-13 | ||
| PCT/EP2019/065016 WO2019234240A1 (en) | 2018-06-07 | 2019-06-07 | Combinations of beta-lactam compounds and probenecid and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410957648.1A Division CN118903120A (zh) | 2018-06-07 | 2019-06-07 | β-内酰胺化合物与丙磺舒的组合及其用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112739338A true CN112739338A (zh) | 2021-04-30 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980052188.5A Pending CN112739338A (zh) | 2018-06-07 | 2019-06-07 | β-内酰胺化合物与丙磺舒的组合及其用途 |
| CN202410957648.1A Pending CN118903120A (zh) | 2018-06-07 | 2019-06-07 | β-内酰胺化合物与丙磺舒的组合及其用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410957648.1A Pending CN118903120A (zh) | 2018-06-07 | 2019-06-07 | β-内酰胺化合物与丙磺舒的组合及其用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11554112B2 (https=) |
| EP (1) | EP3801486A1 (https=) |
| JP (2) | JP2021525787A (https=) |
| CN (2) | CN112739338A (https=) |
| AU (1) | AU2019281018B2 (https=) |
| BR (1) | BR112020024498A2 (https=) |
| TW (1) | TW202005970A (https=) |
| WO (1) | WO2019234240A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112076161A (zh) * | 2020-08-07 | 2020-12-15 | 安徽康正康仁药业有限公司 | 一种头孢菌素类钠盐与丙磺舒钠组成的复方冻干制剂 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11554112B2 (en) | 2018-06-07 | 2023-01-17 | Herum Therapeutics International Limited | Combinations of β-lactam compounds and probenecid and uses thereof |
| MX2021009755A (es) | 2019-02-13 | 2021-11-17 | Iterum Therapeutics International Ltd | Combinaciones de compuestos beta-lactámicos y probenecid, y usos de los mismos. |
| CA3169900A1 (en) * | 2020-03-11 | 2021-09-16 | Iterum Therapeutics International Limited | Combinations of beta-lactam compounds, probenecid, and valproic acid and uses thereof |
| WO2021207606A1 (en) * | 2020-04-10 | 2021-10-14 | University Of Georgia Research Foundation, Inc. | Methods for treatment of coronavirus infections |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| CN111840236B (zh) * | 2020-08-07 | 2022-09-02 | 安徽康正康仁药业有限公司 | 一种注射用美罗培南丙磺舒钠复方冻干制剂 |
| CN111821462A (zh) * | 2020-08-07 | 2020-10-27 | 安徽康正康仁药业有限公司 | 青霉素类钠盐与丙磺舒钠组成的复方冻干制剂 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101479279A (zh) * | 2006-06-28 | 2009-07-08 | 辉瑞产品公司 | 培南前药 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3302335A1 (de) * | 1982-01-26 | 1983-07-28 | Leo Pharmaceutical Products Ltd. A/S (Loevens kemiske Fabrik Produktionsaktieselskab), 2750 Ballerup | Ss-lactamverbindungen, ihre herstellung und sie enthaltendes arzneimittel |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| UA59394C2 (uk) | 1998-03-27 | 2003-09-15 | Каділа Фармацевтікелс (І.Ей) Лтд. | Стійка у фіксованих дозах оральна фармацевтична композиція, що містить антибактеріальний засіб і мікроорганізм одночасно, та спосіб її одержання (варіанти) |
| DE60103299T2 (de) | 2000-10-30 | 2005-05-12 | Lupin Ltd., Mumbai | Schnell zerfallende cefuroxim axetil enthaltende arzneizusammensetzung mit verzögerter wirkstoffabgabe |
| WO2002041876A1 (en) | 2000-11-22 | 2002-05-30 | Lupin Limited | Pharmaceutical composition for controlled release of an active ingredient |
| AU2002224011B2 (en) | 2001-11-19 | 2008-05-01 | Lupin Limited | A pharmaceutical composition for controlled release of a beta-lactam antibiotic |
| CN1853724A (zh) | 2004-12-01 | 2006-11-01 | 吴晓辉 | 丙磺舒钠、钾与β-内酰胺类抗生素组成复方针剂及其用途 |
| CN1813700A (zh) | 2006-03-01 | 2006-08-09 | 吴晓辉 | 丙磺舒钠与青霉素类抗生素组成复方针剂 |
| PE20080940A1 (es) * | 2006-06-28 | 2008-07-09 | Pfizer Prod Inc | Profarmacos de penem |
| US20080125408A1 (en) * | 2006-11-14 | 2008-05-29 | Pfizer Inc | Penem prodrug |
| EP3315124B1 (en) | 2009-11-13 | 2021-01-06 | Astrazeneca AB | Bilayer tablet formulations |
| WO2014149789A1 (en) | 2013-03-15 | 2014-09-25 | Janssen Pharmaceutica Nv | Combination of canagliflozin and probenecid for the treament of hyperuricemia |
| TR201605632A1 (tr) | 2016-04-28 | 2017-11-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Flurbi̇profen ve tramadolün yavaş salinimli kombi̇nasyonlari |
| US11554112B2 (en) | 2018-06-07 | 2023-01-17 | Herum Therapeutics International Limited | Combinations of β-lactam compounds and probenecid and uses thereof |
| MX2021009755A (es) | 2019-02-13 | 2021-11-17 | Iterum Therapeutics International Ltd | Combinaciones de compuestos beta-lactámicos y probenecid, y usos de los mismos. |
| CA3169900A1 (en) | 2020-03-11 | 2021-09-16 | Iterum Therapeutics International Limited | Combinations of beta-lactam compounds, probenecid, and valproic acid and uses thereof |
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2019
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- 2019-06-06 TW TW108119817A patent/TW202005970A/zh unknown
- 2019-06-07 EP EP19733967.4A patent/EP3801486A1/en active Pending
- 2019-06-07 WO PCT/EP2019/065016 patent/WO2019234240A1/en not_active Ceased
- 2019-06-07 CN CN201980052188.5A patent/CN112739338A/zh active Pending
- 2019-06-07 AU AU2019281018A patent/AU2019281018B2/en active Active
- 2019-06-07 BR BR112020024498-8A patent/BR112020024498A2/pt unknown
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- 2019-06-07 CN CN202410957648.1A patent/CN118903120A/zh active Pending
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2022
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2024
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- 2024-08-29 US US18/819,716 patent/US20250127764A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101479279A (zh) * | 2006-06-28 | 2009-07-08 | 辉瑞产品公司 | 培南前药 |
Non-Patent Citations (2)
| Title |
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| MICHAEL DUNNE ET AL.: "A Phase 1 Study to Assess the Pharmacokinetics of Sulopenem Etzadroxil (PF-03709270)" * |
| R CHANDRA ET AL.: "Pharmacokinetics(PK), safety and tolerability of single oral doses of PF-03709270,with and without co-administration of probenecid introduction" * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112076161A (zh) * | 2020-08-07 | 2020-12-15 | 安徽康正康仁药业有限公司 | 一种头孢菌素类钠盐与丙磺舒钠组成的复方冻干制剂 |
| CN112076161B (zh) * | 2020-08-07 | 2022-10-18 | 安徽康正康仁药业有限公司 | 一种头孢菌素类钠盐与丙磺舒钠组成的复方冻干制剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| US11554112B2 (en) | 2023-01-17 |
| JP2021525787A (ja) | 2021-09-27 |
| BR112020024498A2 (pt) | 2021-03-02 |
| US20230218588A1 (en) | 2023-07-13 |
| JP2024107004A (ja) | 2024-08-08 |
| CN118903120A (zh) | 2024-11-08 |
| US20190374516A1 (en) | 2019-12-12 |
| AU2019281018B2 (en) | 2025-01-30 |
| AU2019281018A1 (en) | 2020-12-10 |
| TW202005970A (zh) | 2020-02-01 |
| EP3801486A1 (en) | 2021-04-14 |
| US12109197B2 (en) | 2024-10-08 |
| US20250127764A1 (en) | 2025-04-24 |
| WO2019234240A1 (en) | 2019-12-12 |
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