JP2021525787A - β−ラクタム化合物とプロベネシドの組み合わせとその使用 - Google Patents

β−ラクタム化合物とプロベネシドの組み合わせとその使用 Download PDF

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JP2021525787A
JP2021525787A JP2020568390A JP2020568390A JP2021525787A JP 2021525787 A JP2021525787 A JP 2021525787A JP 2020568390 A JP2020568390 A JP 2020568390A JP 2020568390 A JP2020568390 A JP 2020568390A JP 2021525787 A JP2021525787 A JP 2021525787A
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pharmaceutically acceptable
acceptable salt
lactam compound
administered
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JPWO2019234240A5 (https=
JP2021525787A5 (https=
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マイケル　ダン
ダン マイケル
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イテルム セラピューティクス インターナショナル リミティド
イテルム セラピューティクス インターナショナル リミティド
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Publication of JPWO2019234240A5 publication Critical patent/JPWO2019234240A5/ja
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
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  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020568390A 2018-06-07 2019-06-07 β−ラクタム化合物とプロベネシドの組み合わせとその使用 Pending JP2021525787A (ja)

Priority Applications (1)

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JP2024075901A JP2024107004A (ja) 2018-06-07 2024-05-08 β－ラクタム化合物とプロベネシドの組み合わせとその使用

Applications Claiming Priority (5)

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US201862682116P 2018-06-07 2018-06-07
US62/682,116 2018-06-07
US201962804970P 2019-02-13 2019-02-13
US62/804,970 2019-02-13
PCT/EP2019/065016 WO2019234240A1 (en) 2018-06-07 2019-06-07 Combinations of beta-lactam compounds and probenecid and uses thereof

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JP2021525787A true JP2021525787A (ja) 2021-09-27
JPWO2019234240A5 JPWO2019234240A5 (https=) 2022-06-15
JP2021525787A5 JP2021525787A5 (https=) 2022-06-15

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US (3) US11554112B2 (https=)
EP (1) EP3801486A1 (https=)
JP (2) JP2021525787A (https=)
CN (2) CN112739338A (https=)
AU (1) AU2019281018B2 (https=)
BR (1) BR112020024498A2 (https=)
TW (1) TW202005970A (https=)
WO (1) WO2019234240A1 (https=)

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Publication number Priority date Publication date Assignee Title
US11554112B2 (en) 2018-06-07 2023-01-17 Herum Therapeutics International Limited Combinations of β-lactam compounds and probenecid and uses thereof
MX2021009755A (es) 2019-02-13 2021-11-17 Iterum Therapeutics International Ltd Combinaciones de compuestos beta-lactámicos y probenecid, y usos de los mismos.
CA3169900A1 (en) * 2020-03-11 2021-09-16 Iterum Therapeutics International Limited Combinations of beta-lactam compounds, probenecid, and valproic acid and uses thereof
WO2021207606A1 (en) * 2020-04-10 2021-10-14 University Of Georgia Research Foundation, Inc. Methods for treatment of coronavirus infections
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
CN111840236B (zh) * 2020-08-07 2022-09-02 安徽康正康仁药业有限公司 一种注射用美罗培南丙磺舒钠复方冻干制剂
CN111821462A (zh) * 2020-08-07 2020-10-27 安徽康正康仁药业有限公司 青霉素类钠盐与丙磺舒钠组成的复方冻干制剂
CN112076161B (zh) * 2020-08-07 2022-10-18 安徽康正康仁药业有限公司 一种头孢菌素类钠盐与丙磺舒钠组成的复方冻干制剂

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JPS58128387A (ja) * 1982-01-26 1983-07-30 レオ・フア−マシユ−テイカル・プロダクツ・リミテツド・エイ／エス（レ−ベンス・ケミスケ・フアブリツク・プロデユクチオンスアクチ−セルスカブ） 新規β−ラクタム化合物およびその製法と用途
US20050031685A1 (en) * 2001-11-19 2005-02-10 Himadri Sen Pharmaceutical composition for controlled release of a beta-lactam antibiotic
CN1813700A (zh) * 2006-03-01 2006-08-09 吴晓辉 丙磺舒钠与青霉素类抗生素组成复方针剂
CN1853724A (zh) * 2004-12-01 2006-11-01 吴晓辉 丙磺舒钠、钾与β－内酰胺类抗生素组成复方针剂及其用途
JP2009542616A (ja) * 2006-06-28 2009-12-03 ファイザー・プロダクツ・インク ペネムプロドラッグ

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