CN112494384A - Composition for removing dark eye circles, eye mask and preparation method of eye mask - Google Patents
Composition for removing dark eye circles, eye mask and preparation method of eye mask Download PDFInfo
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- CN112494384A CN112494384A CN202011429475.4A CN202011429475A CN112494384A CN 112494384 A CN112494384 A CN 112494384A CN 202011429475 A CN202011429475 A CN 202011429475A CN 112494384 A CN112494384 A CN 112494384A
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- 239000000203 mixture Substances 0.000 title claims abstract description 83
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 239000000284 extract Substances 0.000 claims abstract description 37
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims abstract description 24
- 108010087806 Carnosine Proteins 0.000 claims abstract description 24
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims abstract description 24
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims abstract description 24
- 229940044199 carnosine Drugs 0.000 claims abstract description 24
- 229920001184 polypeptide Polymers 0.000 claims abstract description 19
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 19
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 19
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims abstract description 18
- 241000195480 Fucus Species 0.000 claims abstract description 10
- 239000003961 penetration enhancing agent Substances 0.000 claims abstract description 9
- 239000002904 solvent Substances 0.000 claims abstract description 7
- 239000002537 cosmetic Substances 0.000 claims abstract description 6
- 229910003460 diamond Inorganic materials 0.000 claims description 20
- 239000010432 diamond Substances 0.000 claims description 20
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 20
- 229940118127 fucus vesiculosus extract Drugs 0.000 claims description 13
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- 238000000034 method Methods 0.000 claims description 11
- 229940116257 pepper extract Drugs 0.000 claims description 11
- SCAKQYSGEIHPLV-IUCAKERBSA-N (4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-(carboxymethylcarbamoyl)pyrrolidin-1-yl]-5-oxopentanoic acid Chemical group NCC(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)NCC(O)=O SCAKQYSGEIHPLV-IUCAKERBSA-N 0.000 claims description 10
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical group NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims description 9
- 239000012752 auxiliary agent Substances 0.000 claims description 8
- 239000002738 chelating agent Substances 0.000 claims description 4
- 239000003906 humectant Substances 0.000 claims description 4
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 4
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- 230000000694 effects Effects 0.000 abstract description 11
- 230000007774 longterm Effects 0.000 abstract description 2
- 210000001508 eye Anatomy 0.000 description 43
- YPFDHNVEDLHUCE-UHFFFAOYSA-N propane-1,3-diol Chemical compound OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 description 34
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 34
- 238000010438 heat treatment Methods 0.000 description 29
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 27
- 238000002156 mixing Methods 0.000 description 19
- 239000000843 powder Substances 0.000 description 19
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 description 18
- 210000003491 skin Anatomy 0.000 description 18
- 229920002385 Sodium hyaluronate Polymers 0.000 description 17
- 229920000058 polyacrylate Polymers 0.000 description 17
- 229940010747 sodium hyaluronate Drugs 0.000 description 17
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 17
- 239000008367 deionised water Substances 0.000 description 16
- 229910021641 deionized water Inorganic materials 0.000 description 16
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 11
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 11
- 241000723353 Chrysanthemum Species 0.000 description 10
- 241000628997 Flos Species 0.000 description 8
- 239000011570 nicotinamide Substances 0.000 description 6
- 229960003966 nicotinamide Drugs 0.000 description 6
- 235000005152 nicotinamide Nutrition 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 5
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- 229920006037 cross link polymer Polymers 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- YXIBXUGCDCJBPD-JYJNAYRXSA-N (2s)-2,6-diamino-n-[2-[[(2s)-1-[[(2s)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1h-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]hexanamide Chemical group NCCCC[C@H](N)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(N)=O)CC1=CN=CN1 YXIBXUGCDCJBPD-JYJNAYRXSA-N 0.000 description 1
- 229940015975 1,2-hexanediol Drugs 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical group OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- 108010005094 Advanced Glycation End Products Proteins 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 108010018924 Heme Oxygenase-1 Proteins 0.000 description 1
- 102100028006 Heme oxygenase 1 Human genes 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- 239000000232 Lipid Bilayer Substances 0.000 description 1
- 206010040829 Skin discolouration Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
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- 238000005282 brightening Methods 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000037319 collagen production Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
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- 238000005562 fading Methods 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000006206 glycosylation reaction Methods 0.000 description 1
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
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- 210000002780 melanosome Anatomy 0.000 description 1
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- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 239000002052 molecular layer Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- MEXQWQLMJYIYPG-UHFFFAOYSA-M potassium;2-oxopyrrolidine-1-carboxylate Chemical compound [K+].[O-]C(=O)N1CCCC1=O MEXQWQLMJYIYPG-UHFFFAOYSA-M 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 description 1
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention belongs to the field of cosmetics and discloses a composition for removing dark eye circles, an eye mask and a preparation method thereof. The composition for removing dark circles comprises the following components: polypeptide mixture, nicotinamide, fucus extract, penetration enhancer and solvent, wherein the polypeptide mixture comprises carnosine, tripeptide and tetrapeptide. The composition provided by the invention has the effect of quickly removing black eye circles, when the eye mask contains the composition, the eye mask can effectively remove the black eye circles, and the effect is obvious within 15 minutes and quick; the black eye can be removed and the function of good control can be achieved after long-term use.
Description
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to a composition for removing dark eye circles, an eye mask and a preparation method thereof.
Background
The eyes are the first of five sense organs and are the important embodiment of the human spirit and appearance. However, many people develop dark circles with high working stress, improper living habits, and aging. The dark eye circles are the pigmentation of the eyes caused by the fact that the blood flow velocity of the vein blood vessels is too slow, the oxygen supply of the erythrocyte cells of the skin of the eyes is insufficient, the accumulation of carbon dioxide and metabolic wastes in the vein blood vessels is excessive, chronic oxygen deficiency is formed, the blood is dark and stagnation is formed.
After the age of 25, the skin begins to slowly slide down, the metabolism of the body is gradually slowed down, the moisture content of the skin is reduced, and the skin becomes dry, dull and lusterless; the skin condition of the eyes will be more obvious and the dark circles will be more obvious.
Many people choose to use the eye mask to improve the problem of dark circles around the eyes. The eye mask can replenish water and eliminate fatigue in a short time, and can play a role in cleaning and protecting eyes at the same time. However, the current eye mask has little effect on eliminating black eyes, and particularly cannot achieve the effect of quickly eliminating the black eyes after the black eyes appear in night-out and other conditions.
Therefore, it is desirable to provide an eye mask capable of rapidly removing dark circles.
Disclosure of Invention
The present invention is directed to solving at least one of the problems of the prior art described above. Therefore, the invention provides a composition for removing black eyes, which can quickly remove the black eyes. The invention also provides an eye mask for removing black eye circles.
In a first aspect of the invention, a composition for removing dark circles is provided.
Specifically, the composition for removing dark circles comprises the following components: polypeptide mixture, nicotinamide, fucus extract, a penetration enhancer and a solvent, wherein the polypeptide mixture is carnosine, tripeptide and tetrapeptide.
Preferably, in the polypeptide mixture, the tetrapeptide is tetrapeptide-4, and the tripeptide is tripeptide-1 and/or palmitoyl tripeptide-8.
Preferably, the penetration enhancer is pepper extract.
Preferably, the composition for removing black eye circles comprises the following components in parts by weight: 0.5-2.5 parts of polypeptide mixture, 1-5 parts of nicotinamide, 0.5-2 parts of Fucus vesiculosus extract, 0.005-0.03 part of penetration enhancer and 65-80 parts of solvent.
Further preferably, the composition for removing black eye circles comprises the following components in parts by weight: 0.5-2 parts of polypeptide mixture, 2-4 parts of nicotinamide, 1-1.5 parts of Fucus vesiculosus extract, 0.01-0.02 part of penetration enhancer and 70-80 parts of solvent.
Preferably, in the polypeptide mixture, the carnosine accounts for 50-90% of the polypeptide mixture by mass; further preferably, in the polypeptide mixture, the carnosine accounts for 60-85% of the polypeptide mixture by mass.
Preferably, the composition for removing dark circles further comprises an auxiliary agent, and the auxiliary agent accounts for 10-30 parts. The content of the preservative in the auxiliary agent accounts for less than 1% of the total mass of the composition. The addition amount of each component in the auxiliary agent meets the requirement of the cosmetic industry standard.
Preferably, the auxiliary agent is selected from at least one of a chelating agent, a humectant, a thickener, a preservative, or a pH adjuster.
Preferably, the chelating agent is EDTA-2 Na.
Preferably, the humectant comprises at least one of propylene glycol, 1, 3-propylene glycol, sodium hyaluronate, butylene glycol, 1, 2-pentanediol, 1, 2-hexanediol, potassium pyrrolidone carboxylate, or sodium pyrrolidone carboxylate.
Preferably, the thickener is at least one of polyacrylate cross-linked polymer-6, cellulose or xanthan gum.
Preferably, the preservative is phenoxyethanol or p-hydroxyacetophenone.
Preferably, the pH regulator is citric acid or sodium citrate.
Preferably, the black eye removing composition further comprises at least one of oligopeptide, gold foil, diamond powder or chrysanthemum extract. The oligopeptide is selected from oligopeptide-1 or oligopeptide-29, and the oligopeptide-1 promotes toxin discharge from the basal layer of the skin and repairs the skin. The gold foil and the diamond powder can enhance the efficacy of the polypeptide mixture and the nicotinamide; the chrysanthemum extract has the function of relieving eyes.
In a second aspect, the present invention provides a method for preparing a composition for removing dark circles.
Specifically, the preparation method of the composition for removing dark circles comprises the following steps:
stirring and dissolving the components to prepare the composition for removing the black eye circles.
Further preferably, the preparation method of the composition for removing dark circles comprises the following steps:
(1) heating and mixing the thickening agent, the chelating agent and the humectant to prepare a phase A;
(2) adding gold foil and diamond powder into solvent, heating and mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) heating and dissolving the penetration enhancer, nicotinamide, polypeptide mixture and the rest components, then adding the phase C, homogenizing, and stirring to obtain the composition for removing dark circles.
Preferably, the temperature for heating and mixing in the step (1) and the step (2) is 75-85 ℃; further preferably 75 to 80 ℃.
Preferably, the temperature for heating and dissolving in the step (3) is below 40 ℃; further preferably 30 to 40 ℃.
In a third aspect of the present invention, there is provided a cosmetic comprising the black eye removing composition.
An eye mask comprising the composition for removing dark circles.
The invention also provides an application of the composition in preparing cosmetics.
Excessive sugar in human body can be combined with collagen, enzyme and DNA through non-enzymatic glycosylation reaction to finally generate advanced glycosylation end products AGEs, the AGEs can destroy collagen to cause skin to lack elasticity, and the damage of the AGEs to human skin is irreversible. It is produced and accumulated in serum tissues with age. This is one of the reasons for the formation of dark circles.
The carnosine is adopted to play a role in resisting sugar, and the carnosine is an effective AGEs inhibitor, can inhibit the generation of AGEs and can be combined with the formed AGEs to inactivate the AGEs; tripeptides and tetrapeptides enhance the anti-carbohydrate depigmenting ability of carnosine; the Fucus vesiculosus extract can promote HO-1 protein accumulation in fibroblast, promote I type collagen production, make eye collagen abundant, and reduce eye shadow; niacinamide inhibits melanosome migration to the skin surface and has a skin lightening effect. The pepper extract can increase the fluidity of lipid cream molecular layer by interfering intercellular lipid of skin stratum corneum, and the increased fluidity can promote the diffusion of carnosine, tripeptide, tetrapeptide, Fucus vesiculosus extract and nicotinamide, and pass through the hydrocarbon part of lipid bilayer to achieve the effects of promoting the rapid and effective permeation of functional components and eliminating the dark eye circles of eyes in a short time.
Compared with the prior art, the invention has the following beneficial effects:
the composition has the effect of quickly removing black eye circles, when the eye mask contains the composition, the eye mask can effectively remove the black eye circles, and the effect is obvious within 15 minutes and quick; the black eye can be removed and the function of good control can be achieved after long-term use.
Detailed Description
In order to make the technical solutions of the present invention more apparent to those skilled in the art, the following examples are given for illustration. It should be noted that the following examples are not intended to limit the scope of the claimed invention.
The starting materials, reagents or apparatuses used in the following examples are conventionally commercially available or can be obtained by conventionally known methods, unless otherwise specified.
Example 1
A composition for removing dark circles comprises the following components: carnosine 1.25 parts, tripeptide-10.3 parts, tetrapeptide-40.35 parts, fucus extract 1.2 parts, nicotinamide 3 parts, pepper extract 0.01 part, deionized water 75 parts, polyacrylate cross-linked polymer-60.6 parts, EDTA-2Na0.02 part, 1, 3-propylene glycol 1 part, sodium hyaluronate 1 part, gold foil 2 parts, diamond powder 0.001 part, chrysanthemum extract 5 parts, citric acid 0.1 part, and p-hydroxyacetophenone 0.12 part.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) dissolving flos Chrysanthemi extract, carnosine, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C under heating, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Example 2
A composition for removing dark circles comprises the following components: carnosine 1.25 parts, palmitoyl tripeptide-80.3 parts, tetrapeptide-40.35 parts, nicotinamide 1 part, fucus extract 1.2 parts, pepper extract 0.01 part, deionized water 75 parts, polyacrylate cross-linked polymer-60.6 parts, EDTA-2Na0.02 part, 1, 3-propylene glycol 1 part, sodium hyaluronate 1 part, gold foil 2 part, diamond powder 0.001 part, chrysanthemum extract 5 parts, citric acid 0.1 part, and p-hydroxyacetophenone 0.12 part.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) dissolving flos Chrysanthemi extract, carnosine, palmitoyl tripeptide-8, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C under heating, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Example 3
A composition for removing dark circles comprises the following components: 0.6 part of carnosine, 10.3 parts of tripeptide, 40.35 parts of tetrapeptide, 5 parts of nicotinamide, 1.5 parts of fucus extract, 0.02 part of pepper extract, 75 parts of deionized water, 60.6 parts of polyacrylate cross-linked polymer, 0.02 part of EDTA-2Na, 1, 3-propylene glycol, 1 part of sodium hyaluronate, 2 parts of gold foil, 0.001 part of diamond powder, 5 parts of chrysanthemum extract, 0.1 part of citric acid and 0.12 part of p-hydroxyacetophenone.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) dissolving flos Chrysanthemi extract, carnosine, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C under heating, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Example 4
A composition for removing dark circles comprises the following components: carnosine 1.25 parts, tripeptide-10.3 parts, tetrapeptide-40.35 parts, fucus extract 0.5 part, nicotinamide 3 parts, pepper extract 0.01 part, deionized water 75 parts, polyacrylate cross-linked polymer-60.6 parts, EDTA-2Na0.02 part, 1, 3-propylene glycol 1 part, sodium hyaluronate 1 part, gold foil 2 parts, diamond powder 0.001 part, chrysanthemum extract 5 parts, citric acid 0.1 part, and p-hydroxyacetophenone 0.12 part.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) dissolving flos Chrysanthemi extract, carnosine, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C under heating, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Example 5
A composition for removing dark circles comprises the following components: carnosine 1.25 parts, tripeptide-10.8 parts, tetrapeptide-40.7 parts, nicotinamide 0.5 parts, fucus extract 1.2 parts, pepper extract 0.01 parts, deionized water 75 parts, polyacrylate cross-linked polymer-60.6 parts, EDTA-2Na0.02 parts, 1, 3-propylene glycol 1 part, sodium hyaluronate 1 part, gold foil 2 parts, diamond powder 0.001 part, chrysanthemum extract 5 parts, citric acid 0.1 part, and p-hydroxyacetophenone 0.12 part.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) dissolving flos Chrysanthemi extract, carnosine, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C under heating, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Comparative example 1
A composition for removing dark circles comprises the following components: 11 parts of tripeptide-11 parts, 40.9 parts of tetrapeptide-3 parts of nicotinamide, 1.2 parts of fucus extract, 0.01 part of pepper extract, 75 parts of deionized water, 60.6 parts of polyacrylate cross-linked polymer, 0.02 part of EDTA-2Na, 1 part of 1, 3-propylene glycol, 1 part of sodium hyaluronate, 2 parts of gold foil, 0.001 part of diamond powder, 5 parts of chrysanthemum extract, 0.1 part of citric acid and 0.12 part of p-hydroxyacetophenone.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) heating flos Chrysanthemi extract, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C for dissolving, adding phase C, homogenizing, and stirring to obtain composition for removing black eye.
Comparative example 2
A composition for removing dark circles comprises the following components: 2.4 parts of carnosine, 11.2 parts of tripeptide, 40.8 parts of tetrapeptide, 1.5 parts of fucus extract, 0.01 part of pepper extract, 75 parts of deionized water, 60.6 parts of polyacrylate cross-linked polymer, 0.02 part of EDTA-2Na, 1 part of 1, 3-propylene glycol, 1 part of sodium hyaluronate, 2 parts of gold foil, 0.001 part of diamond powder, 5 parts of chrysanthemum extract, 0.1 part of citric acid and 0.12 part of p-hydroxyacetophenone.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) heating flos Chrysanthemi extract, carnosine, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, fructus Piperis extract and the rest components in water bath at 40 deg.C for dissolving, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Comparative example 3
A composition for removing dark circles comprises the following components: 1.4 parts of carnosine, 10.3 parts of tripeptide, 40.4 parts of tetrapeptide, 4 parts of nicotinamide, 0.01 part of pepper extract, 75 parts of deionized water, 60.6 parts of polyacrylate cross-linked polymer, 0.02 part of EDTA-2Na0, 1 part of 1, 3-propylene glycol, 1 part of sodium hyaluronate, 2 parts of gold foil, 0.001 part of diamond powder, 5 parts of chrysanthemum extract, 0.1 part of citric acid and 0.12 part of p-hydroxyacetophenone.
A method for preparing a composition for removing dark circles comprises the following steps:
(1) heating deionized water, polyacrylate cross-linked polymer-6, EDTA-2Na, 1, 3-propylene glycol and sodium hyaluronate to 80 ℃, and mixing to obtain phase A;
(2) adding gold foil and diamond powder into water, heating to 80 deg.C, mixing to obtain phase B, adding phase B into phase A, stirring, and homogenizing to obtain phase C;
(3) dissolving flos Chrysanthemi extract, carnosine, tripeptide-1, tetrapeptide-4, Fucus vesiculosus extract, nicotinamide, fructus Piperis extract and the rest components in water bath at 40 deg.C under heating, adding phase C, homogenizing, and stirring to obtain composition for removing dark eye circle.
Product effectiveness testing
The black eye removing compositions prepared in examples 1 to 5 and comparative examples 1 to 3 were formed into eye masks by a conventional method, respectively. 24 subjects aged between 25-35 were then organized for efficacy testing. The subjects were randomly divided into 8 groups of 3 persons each, and the effect of removing dark circles was tested with one eye membrane per group, and the specific groups are shown in table 1. The test conditions were: keeping the temperature at 25 ℃ and the humidity at 40-60%; after the subjects cleaned their faces with warm water, they were allowed to rest in a constant temperature and humidity room for 0.5 to 1 hour before use. The eye mask was then applied to the lower eyelid and outer canthus of the test subjects for 15 minutes and then removed and massaged for absorption, and tested and self-rated after use. The skin quality, brightness of the skin was tested using the C-Cube multifunctional skin imaging analysis system from PIXIENCE, Inc., and the testers were self-rated for periocular skin gloss and black eye rating. The test results are shown in Table 1.
TABLE 1
Note: the L value represents luminance, where completely dark (L ═ 0) to absolutely white (L ═ 100);
ITA ° (individual type angle) represents skin tone: less than 10 deg. is brown, 10-28 deg. is brown, 28-41 deg. is normal color, 41-55 deg. is white, and more than 55 deg. is very white.
As can be seen from Table 1, the L value and ITA DEG of the eye skin of the testers using the eye masks prepared from the compositions of examples 1-5 are obviously increased, which indicates that the skin at the black eye part is brighter and whiter, and the composition for removing the black eye part has the effects of quickly fading the black eye part and brightening the skin color of the eye part; and the effects of examples 1-5 are significantly better than those of comparative examples 1-3.
Claims (10)
1. The composition for removing dark eye circles is characterized by comprising the following components: polypeptide mixture, nicotinamide, fucus extract, penetration enhancer and solvent, wherein the polypeptide mixture comprises carnosine, tripeptide and tetrapeptide.
2. The composition of claim 1, wherein in the mixture of polypeptides the tetrapeptide is tetrapeptide-4 and the tripeptide is tripeptide-1 and/or palmitoyl tripeptide-8.
3. The composition of claim 1, wherein the penetration enhancer is pepper extract.
4. The composition according to claim 1, characterized by comprising the following components in parts by weight: 0.5-2.5 parts of polypeptide mixture, 1-5 parts of nicotinamide, 0.5-2 parts of Fucus vesiculosus extract, 0.005-0.03 part of penetration enhancer and 65-80 parts of solvent.
5. The composition according to claim 1, wherein the carnosine is present in the mixture of polypeptides in an amount of 50% to 90% by weight of the mixture of polypeptides.
6. The composition according to claim 1, wherein the composition for removing dark circles further comprises an auxiliary agent, the auxiliary agent is 10-30 parts, and the auxiliary agent is at least one selected from a chelating agent, a humectant, a thickener, a preservative or a pH regulator.
7. The composition of claim 6, further comprising at least one of an oligopeptide, gold foil, diamond dust, or chrysanthemum extract.
8. A process for the preparation of a composition according to any one of claims 1 to 7, characterized in that it comprises the following steps:
and stirring and dissolving the components to prepare the composition.
9. An ophthalmic membrane comprising the composition of any one of claims 1 to 7.
10. Use of a composition according to any one of claims 1 to 7 for the preparation of a cosmetic product.
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| CN113827541A (en) * | 2021-09-26 | 2021-12-24 | 湖北省麦诗特生物科技有限公司 | Essence emulsion composition with black eye and pouch removing effects and preparation method thereof |
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