CN113952277A - Microcrystalline peptide anti-wrinkle face cream and preparation method thereof - Google Patents
Microcrystalline peptide anti-wrinkle face cream and preparation method thereof Download PDFInfo
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- CN113952277A CN113952277A CN202111430123.5A CN202111430123A CN113952277A CN 113952277 A CN113952277 A CN 113952277A CN 202111430123 A CN202111430123 A CN 202111430123A CN 113952277 A CN113952277 A CN 113952277A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention relates to microcrystalline peptide anti-wrinkle face cream, and belongs to the technical field of daily chemical products. The microcrystalline peptide anti-wrinkle face cream is prepared from the following raw materials in percentage by weight: emulsifier: 2-2.5%, thickener: 1-1.5% and a humectant: 10-18% of oil and fat: 6-10% and preservative: 1.5-2%, anti-allergy repair: 1-2%, hydrolyzed sponge: 1-3.5%, carnosine: 0.5-3%, recombinant collagen: 0.5-3%, hexapeptide-9: 0.5-3%, dendrobium officinale extract: 0.5-3%, water: and (4) the balance. The microcrystalline peptide anti-wrinkle face cream disclosed by the invention can stimulate the bone collagen proliferation without damaging the surface layer of the skin so as to awaken and improve the regeneration capacity of the skin, promotes the absorption of active substances such as carnosine, recombinant collagen, hexapeptide-9, dendrobium officinale extract and the like, and has the effects of remarkably improving the texture of the skin, uniformly mixing the skin color and increasing the elasticity of the skin so as to reduce wrinkles; solves the problem that the skin becomes sensitive due to excessive cutin removal in the anti-wrinkle process of the existing skin care product.
Description
Technical Field
The invention relates to microcrystalline peptide anti-wrinkle face cream and a preparation method thereof, belonging to the technical field of daily chemical products.
Background
With the aging, the collagen content in the skin is less and less, the skin is easy to relax and droop, wrinkles appear, and the process of skin aging is the process of collagen loss. The key step of anti-aging is to supplement lost collagen. Various anti-aging products are also available on the market, but most of these products act on the stratum corneum of the skin, are absorbed through the stratum corneum and reach the epidermis and dermis layers. When the horny layer is too thick, the skin care product is difficult to permeate and absorb, so a series of exfoliating products are derived from the market, but excessive exfoliating can cause the skin to be thin, red blood streaks appear, the skin becomes sensitive easily, and the skin care product is easy to cause allergy. Therefore, it is necessary to develop a microcrystalline peptide anti-wrinkle cream to solve the above problems.
Disclosure of Invention
The invention aims to: provides a microcrystalline peptide anti-wrinkle face cream which does not need to remove cutin and is easy to be absorbed by skin so as to solve the problem that the skin becomes sensitive due to excessive cutin removal in the anti-wrinkle process of the existing skin care products and a preparation method thereof.
The technical scheme of the invention is as follows:
the microcrystalline peptide anti-wrinkle face cream is characterized in that: the paint comprises the following components in percentage by weight:
emulsifier: 2-2.5% thickener: 1 to 1.5 percent
Humectant: 10-18% of grease: 6 to 10 percent
Preservative: 1.5-2% anti-allergy repair: 1 to 2 percent
Hydrolyzing the sponge: 1-3.5% carnosine: 0.5 to 3 percent
Recombinant collagen protein: 0.5-3% hexapeptide-9: 0.5 to 3 percent
The dendrobium officinale extract: 0.5-3% water: and (4) the balance.
The microcrystalline peptide anti-wrinkle face cream is characterized in that: the paint comprises the following components in percentage by weight:
emulsifier: 2-2.5% thickener: 1 to 1.5 percent
Humectant: 10-18% of grease: 6 to 10 percent
Preservative: 1.5-2% anti-allergy repair: 1 to 2 percent
Hydrolyzing the sponge: 2% carnosine: 2 percent of
Recombinant collagen protein: 2% hexapeptide-9: 1 percent of
The dendrobium officinale extract: 1% of water: and (4) the balance.
The emulsifier comprises Emulfeel SGP CHI and polysorbate-60.
Said Emulfeel SGP CHI comprises sunflower (Helianthus ANNUUS) seed oil, sodium polyacrylate, xylitol, caprylic acid, glyceryl stearate, and tocopherol (vitamin E).
The thickening agent comprises xanthan gum, acryloyl dimethyl ammonium taurate/VP copolymer and hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer.
The humectant comprises glycerin, glyceryl polyether-26, trehalose, sodium hyaluronate and Gerber gum-CG.
The Gemba-CG comprises glycerol polymethacrylate and glycerol.
The grease comprises polydimethylsiloxane and ethylhexyl palmitate.
The preservative comprises p-hydroxyacetophenone and 1, 2-hexanediol.
The anti-allergy repairing agent is oat (AVENA SATIVA) kernel extract and oligopeptide-1.
A preparation method of microcrystalline peptide anti-wrinkle face cream is characterized by comprising the following steps: it comprises the following steps:
1) weighing the components in proportion;
2) homogenizing the humectant, the thickener and water at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials;
3) heating the emulsifier and the grease to 80-85 ℃, then adding the heated emulsifier and the grease into the material obtained in the step 2), homogenizing for 3-4min at the rotating speed of 20-25r/min, stirring at the rotating speed of 20-30r/min after homogenizing, and keeping the temperature for 20-30 min;
4) naturally cooling the heat-insulated materials, adding a preservative into the materials obtained in the step 3) when the temperature is reduced to 65-70 ℃, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials;
5) and continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the preservative, the anti-allergy repair, the hydrolyzed sponge, the carnosine, the recombinant collagen, the hexapeptide-9 and the dendrobium officinale extract into the materials obtained in the step 4), stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
Carnosine in the microcrystalline peptide anti-wrinkle cream is water-soluble dipeptide, can effectively inhibit glycosylation reaction, can inhibit the generation of AGEs (advanced glycosylation end products), and can be combined with the produced AGEs to inactivate the AGEs, so that glycosylation of other proteins and polypeptides is prevented, breakage and disorder of collagen are reduced, and the consequences of skin relaxation, wrinkles and dark yellow skin are avoided.
The recombinant collagen takes a type III collagen gene as a template, and is highly consistent with the collagen of a human body through microbial fermentation engineering and purification, so that the recombinant collagen is more beneficial to skin absorption and can promote the skin to supplement exogenous collagen.
Hexapeptide-9 is a very stable collagen peptide, and the structure of this peptide exists in both collagen IV and XVII (two key basement membrane collagens) of the human body, thus increasing the production of both types of collagen, and thus being effective against skin laxity, making the skin more elastic and firmer.
The dendrobium officinale extract contains rich active polysaccharide, enhances the activity of cells, and ensures that epidermal tissues consisting of the cells are plump and glossy; a large amount of colloid contained in the dendrobium officinale, and the colloid is the most main source for supplementing collagen in human skin; in the traditional Chinese medicine, yin and yang are balanced, water belongs to the scope of yin, the water of human bodies and skin is lost, the root of the dendrobium officinale is yin deficiency, the dendrobium officinale has a very good yin nourishing effect in all traditional Chinese medicinal materials, the skin is naturally moistened and whitened in a balanced state, and the dendrobium officinale is powdery and tender.
The hydrolysis sponge is a siliceous microcrystalline spicule, acts on the epidermis skin to form a large number of tiny pipelines, thereby forming a delivery channel between the epidermis and the subcutaneous tissue, promoting the introduction of active ingredients, and penetrating and blocking hair follicles.
The invention has the beneficial effects that:
the microcrystalline peptide anti-wrinkle cream stimulates the skin through a plurality of tiny bone needles formed by the hydrolyzed sponge, and micro needles can make over millions of micro pipelines in a short time, so that the hydrolyzed sponge penetrates through the cortex, a channel of the skin is opened, active ingredients effectively permeate into the skin, act on the epidermal skin, perform epidermal circulation, and promote the microcirculation of the muscle bottom, so that the active ingredients can be better and faster absorbed, the utilization rate of the active ingredients is improved, particularly the absorptivity and the utilization rate of carnosine, recombinant collagen and hexapeptide-9 are improved, and the formation of more collagens is promoted, so that the cutin of the skin is not required to be removed; meanwhile, the sponge micro-needle stimulates the dermis layer to stimulate the skin, shortens the metabolic cycle of the skin, improves the regeneration capability of the skin, activates the regeneration of collagen and elastin and promotes the collagen proliferation by stimulating the self-healing capability of the skin; through the design idea of 'first resistance, second supplement and third balance', firstly, the carnosine is used for preventing the collagen glycosylation reaction of the skin, and the loss of the existing collagen is blocked or reduced; then, hexapeptide-9 and recombinant collagen are utilized to promote the absorption and synthesis of the collagen; finally, through the concept of yin-yang balance in the traditional Chinese medicine, the dendrobium officinale extract is used for supplementing a large amount of colloid and water at the same time, so that the condition of yin deficiency of women generally over 25 years old is improved, the skin is plump and glossy, and the effect of resisting wrinkles is achieved; solves the problem that the skin becomes sensitive due to excessive cutin removal in the anti-wrinkle process of the existing skin care product.
In order to highlight the efficacy of the microcrystalline peptide anti-wrinkle face cream, the following comparative verification is carried out, and the process is as follows:
setting 5 test groups and 4 control groups, and weighing the following components in percentage by weight:
TABLE 1 ingredient table
Preparing the microcrystalline peptide anti-wrinkle face cream for later use by the preparation method of the microcrystalline peptide anti-wrinkle face cream;
and (3) testing:
the experimental population is as follows: 108 persons, screening conditions: volunteers aged 25-35 years, 54 males and 54 females, all of whom had not used other anti-aging products within the last three months.
The testing process comprises the following steps:
dividing the experimental population into 9 groups randomly, wherein 6 males and 6 females in each group are obtained;
each group uses the corresponding face cream, and the face cream is used once in the morning and at the evening each day for 28 days continuously;
during the use of the cream, all people were documented by ANTSCI VISIA (image analyzer) by photographing at 10:00 am every 7 days, and the average change of wrinkles in each group was counted.
The test results are given in the following table:
TABLE 2 statistical table of test results
The comparison of the statistical results shows that: when the formula system only contains carnosine, recombinant collagen, hexapeptide-9 and the dendrobium officinale extract or only contains hydrolyzed sponge, the anti-wrinkle effect is not obvious as shown in the test results of the control group 2 and the control group 3; however, when the carnosine, the recombinant collagen, the hexapeptide-9, the dendrobium officinale extract and the hydrolyzed sponge are compounded in the formula system, from the results of the control group 2, the control group 3 and the test group 2, the anti-wrinkle effect is better than that of single use, and wrinkles are obviously reduced, so that the carnosine, the recombinant collagen, the hexapeptide-9, the dendrobium officinale extract and the hydrolyzed sponge can play a role in synergy; when the component ratio of carnosine, recombinant collagen, hexapeptide-9, the dendrobium officinale extract and the hydrolyzed sponge is 4:4:4:2, the wrinkle reduction effect can exceed 20% after the composition is continuously used for 28 days, and the effect is optimal.
Detailed Description
Example 1
Weighing the components according to the following weight percentage:
after weighing, homogenizing the group A materials at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials; dissolving group A materials, heating group B materials to 80-85 deg.C, adding into the dissolved group A materials, homogenizing at 20-25r/min for 3-4min, stirring at 20-30r/min, and maintaining the temperature for 20-30 min; naturally cooling the heat-insulated materials, when the temperature is reduced to 65-70 ℃, adding the group C materials into the materials, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials; and after uniformly stirring, continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the D materials into the materials, stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
Example 2
Weighing the components according to the following weight percentage:
after weighing, homogenizing the group A materials at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials; dissolving group A materials, heating group B materials to 80-85 deg.C, adding into the dissolved group A materials, homogenizing at 20-25r/min for 3-4min, stirring at 20-30r/min, and maintaining the temperature for 20-30 min; naturally cooling the heat-insulated materials, when the temperature is reduced to 65-70 ℃, adding the group C materials into the materials, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials; and after uniformly stirring, continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the D materials into the materials, stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
Example 3
Weighing the components according to the following weight percentage:
after weighing, homogenizing the group A materials at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials; dissolving group A materials, heating group B materials to 80-85 deg.C, adding into the dissolved group A materials, homogenizing at 20-25r/min for 3-4min, stirring at 20-30r/min, and maintaining the temperature for 20-30 min; naturally cooling the heat-insulated materials, when the temperature is reduced to 65-70 ℃, adding the group C materials into the materials, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials; and after uniformly stirring, continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the D materials into the materials, stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
Example 4
Weighing the components according to the following weight percentage:
after weighing, homogenizing the group A materials at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials; dissolving group A materials, heating group B materials to 80-85 deg.C, adding into the dissolved group A materials, homogenizing at 20-25r/min for 3-4min, stirring at 20-30r/min, and maintaining the temperature for 20-30 min; naturally cooling the heat-insulated materials, when the temperature is reduced to 65-70 ℃, adding the group C materials into the materials, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials; and after uniformly stirring, continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the D materials into the materials, stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
Example 5
Weighing the components according to the following weight percentage:
after weighing, homogenizing the group A materials at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials; dissolving group A materials, heating group B materials to 80-85 deg.C, adding into the dissolved group A materials, homogenizing at 20-25r/min for 3-4min, stirring at 20-30r/min, and maintaining the temperature for 20-30 min; naturally cooling the heat-insulated materials, when the temperature is reduced to 65-70 ℃, adding the group C materials into the materials, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials; and after uniformly stirring, continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the D materials into the materials, stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
Claims (9)
1. The microcrystalline peptide anti-wrinkle face cream is characterized in that: the paint comprises the following components in percentage by weight:
emulsifier: 2-2.5% thickener: 1 to 1.5 percent
Humectant: 10-18% of grease: 6 to 10 percent
Preservative: 1.5-2% anti-allergy repair: 1 to 2 percent
Hydrolyzing the sponge: 1-3.5% carnosine: 0.5 to 3 percent
Recombinant collagen protein: 0.5-3% hexapeptide-9: 0.5 to 3 percent
The dendrobium officinale extract: 0.5-3% water: and (4) the balance.
2. The microcrystalline peptide anti-wrinkle cream according to claim 1, characterized in that: the paint comprises the following components in percentage by weight:
emulsifier: 2-2.5% thickener: 1 to 1.5 percent
Humectant: 10-18% of grease: 6 to 10 percent
Preservative: 1.5-2% anti-allergy repair: 1 to 2 percent
Hydrolyzing the sponge: 2% carnosine: 2 percent of
Recombinant collagen protein: 2% hexapeptide-9: 1 percent of
The dendrobium officinale extract: 1% of water: and (4) the balance.
3. A microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, characterized in that: the emulsifier comprises Emulfeel SGP CHI and polysorbate-60;
the Emulfeel SGP CHI comprises sunflower seed oil, sodium polyacrylate, xylitol, caprylic acid, glyceryl stearate and tocopherol.
4. A microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, characterized in that: the thickening agent comprises xanthan gum, acryloyl dimethyl ammonium taurate/VP copolymer and hydroxyethyl acrylate/acryloyl dimethyl sodium taurate copolymer.
5. A microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, characterized in that: the humectant comprises glycerin, glyceryl polyether-26, trehalose, sodium hyaluronate and Gerber gum-CG;
the Gemba-CG comprises glycerol polymethacrylate and glycerol.
6. A microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, characterized in that: the grease comprises polydimethylsiloxane and ethylhexyl palmitate.
7. A microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, characterized in that: the preservative comprises p-hydroxyacetophenone and 1, 2-hexanediol.
8. A microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, characterized in that: the anti-allergy repairing agent comprises oat kernel extract and oligopeptide-1.
9. The method for preparing the microcrystalline peptide anti-wrinkle cream according to any one of claims 1-2, wherein the microcrystalline peptide anti-wrinkle cream comprises the following components: it comprises the following steps:
1) weighing the components in proportion;
2) homogenizing the humectant, the thickener and water at a rotation speed of 20-25r/min for 2-3min, and heating the materials to 80-85 ℃ to completely dissolve the materials;
3) heating the emulsifier and the grease to 80-85 ℃, then adding the heated emulsifier and the grease into the material obtained in the step 2), homogenizing for 3-4min at the rotating speed of 20-25r/min, stirring at the rotating speed of 20-30r/min after homogenizing, and keeping the temperature for 20-30 min;
4) naturally cooling the heat-insulated materials, adding a preservative into the materials obtained in the step 3) when the temperature is reduced to 65-70 ℃, and stirring at the rotating speed of 20-30r/min for 10-15min to uniformly stir the materials;
5) and continuously naturally cooling the materials, when the temperature is reduced to 40-45 ℃, adding the preservative, the anti-allergy repair, the hydrolyzed sponge, the carnosine, the recombinant collagen, the hexapeptide-9 and the dendrobium officinale extract into the materials obtained in the step 4), stirring for 15-20min at the rotating speed of 20-30r/min, and sequentially detecting, filtering and discharging the obtained materials to obtain the face cream.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115487348A (en) * | 2022-09-23 | 2022-12-20 | 广东粤港澳大湾区黄埔材料研究院 | Composition containing recombinant humanized collagen and preparation method and application thereof |
| CN116617147A (en) * | 2023-06-02 | 2023-08-22 | 上海春之葆生物科技有限公司 | Skin soothing and repairing composition and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040213753A1 (en) * | 2000-04-04 | 2004-10-28 | Kenji Nakamura | Method for stimulating cell growth using sponge protein hydrolysates |
| CN110393689A (en) * | 2019-05-31 | 2019-11-01 | 广东盛美化妆品有限公司 | It is a kind of to have effects that anti-ageing essence composition and preparation method thereof |
| CN110882195A (en) * | 2019-12-23 | 2020-03-17 | 广州倍健医疗用品有限公司 | Collagen moisturizing and anti-wrinkle composition and preparation method thereof |
| CN111840193A (en) * | 2020-07-13 | 2020-10-30 | 杭州芊颜化妆品有限公司 | Skin care cream capable of improving skin absorption rate |
| CN113546153A (en) * | 2021-07-30 | 2021-10-26 | 陈翠华 | Anti-aging composition capable of activating cells and preparation method thereof |
-
2021
- 2021-11-29 CN CN202111430123.5A patent/CN113952277A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040213753A1 (en) * | 2000-04-04 | 2004-10-28 | Kenji Nakamura | Method for stimulating cell growth using sponge protein hydrolysates |
| CN110393689A (en) * | 2019-05-31 | 2019-11-01 | 广东盛美化妆品有限公司 | It is a kind of to have effects that anti-ageing essence composition and preparation method thereof |
| CN110882195A (en) * | 2019-12-23 | 2020-03-17 | 广州倍健医疗用品有限公司 | Collagen moisturizing and anti-wrinkle composition and preparation method thereof |
| CN111840193A (en) * | 2020-07-13 | 2020-10-30 | 杭州芊颜化妆品有限公司 | Skin care cream capable of improving skin absorption rate |
| CN113546153A (en) * | 2021-07-30 | 2021-10-26 | 陈翠华 | Anti-aging composition capable of activating cells and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115487348A (en) * | 2022-09-23 | 2022-12-20 | 广东粤港澳大湾区黄埔材料研究院 | Composition containing recombinant humanized collagen and preparation method and application thereof |
| CN116617147A (en) * | 2023-06-02 | 2023-08-22 | 上海春之葆生物科技有限公司 | Skin soothing and repairing composition and preparation method thereof |
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