CN106309349A - Compound for removing black eye and relieving wrinkles, preparation method and application thereof - Google Patents
Compound for removing black eye and relieving wrinkles, preparation method and application thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract
The invention relates to a compound for removing black eye and relieving wrinkles, a preparation method and an application thereof. The compound for removing black eye and relieving wrinkles comprises the following components in parts by weight: 0.01-0.05% of sodium hyaluronate, 1-5% of glycerinum, 1-5% of butanediol, 1-10% of European horse chestnut extracts, 0.5-10% of long carob bean seed extracts, 0.5-10% of purslane extracts, 1-10% of ceramide, 1-10% of beta-glucan, 1-10% of decarboxylation carnosine, 0.1-1% of cell growth factor stock solution, 0.1-2% of astaxanthin, 1-10% of cocoa extracts, 1-10% of olibanum extracts, 1-10% of lactobacillus/North America eriodictyon fermented extracts, 0.2-1% of preservatives and the balance of water. The compound provided by the invention can restrain the forming of melanin by restraining the activity of inflammatory reaction enzyme, can enhance skin barrier and can supplement eye skin nutrition so as to achieve the effect of removing black eye and relieving wrinkles.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of compositions and preparation side thereof going black eye and desalinating microgroove
Method and application.
Background technology
Black eye are also that we often say " panda eye ", and black eye divide two kinds: one is cyan black eye, its mainly by
Stay up late, emotional instability, eye strain, aging, eye part skin red blood cell for hypoxgia, in vein blood vessel carbon dioxide and
Metabolic waste accumulation too much, forms chronic hypoxia, and blood is dark and venous blood in vein blood vessel or blood capillary is detained and makes
Become.Another kind is dark brown black eye, and its main cause is the eye pigmentation that melanin generates or metabolism causes the most entirely.Year
Record the biggest people, and the subcutaneous fat around eyes becomes the thinnest, so black eye just become apparent from.
Two kinds of black eye Producing reason are entirely different.Cyan black eye usually occur in about 20 years old, and daily life system is not
Normal people You Nan avoids.Students ' Learning pressure is relatively big now, and youngster is stayed up late and had become as homely food, so there is black eye
There is the trend moved down at the age of the crowd of circle, and in the crowd of more than 18 years old, black eye are the most universal.Dark brown black-eyed one-tenth
Because then increasing closely bound up with the age, chronic sun exposure causes pigementation near the eyes, will be formed in the course of time and can't get rid of
Black eye.Additionally, the pigmentation after the inflammatory reactions such as erythema, in skin corium, Melanin Metabolism is slow, skin is over-drying, also can
Cause or increase the weight of dark brown black-eyed formation.
At present, market occurs in that whitening product miscellaneous, but these whitening series products major parts with face are
Main, little whitening series products is the qualitative modification done for circumference of eyes skin.And the lightening mechanism of existing whitening product
Mainly suppress generation or its activity, the melanin that reduction has generated of tryrosinase, accelerate the decomposition of tryrosinase.Existing
Alleviate that black-eyed product can not well alleviate that the pigmentation caused by inflammatory reaction or metabolism slowly cause is black
Eyelet problem.Therefore, still need to research and develop a kind of novel can removing black eye and desalinate compositions and the preparation thereof of microgroove
Method.
Summary of the invention
It is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of combination removing black eye and desalination microgroove
Thing, the compositions that the present invention provides can suppress melanic formation by the activity of suppression proinflammatory enzyme, strengthen skin
Skin barrier, supplements eye part skin nutrition thus reaches the effect of black eye desalination microgroove.
Another object of the present invention is to provide the preparation method of the above-mentioned compositions removing black eye and desalination microgroove.
Another object of the present invention is to provide above-mentioned goes the compositions of black eye and desalination microgroove at eye skin-protection product
In application.
Another object of the present invention is to provide a kind of eye skin-protection product removing black eye and desalination microgroove.
For achieving the above object, the present invention adopts the following technical scheme that
A kind of go black eye and desalination microgroove compositions, described in go black eye and desalination microgroove compositions by following matter
The component composition of amount percentage ratio:
Hyaluronate sodium 0.01～0.05%；Glycerol 1～5%；Butanediol 1～5%；Aesculus hippocastanum L. extract 1～
10%；Algaroba seed extract 0.5～10%；Herba portulacae extract 0.5～10%；Cer EOS～10%；Beta glucan 1
～10%；Decarboxylation carnosine 1～10%；Cell growth factor stock solution 0.1～1%；Astaxanthin 0.1～2%；Cocoa extract 1～
10%；Olibanum extract 1～10%；Lactobacillus/bear's weed fermented product extract 1～10%；Preservative 0.2～1%, surplus
For water.
Skin tissue below eye is the thinnest and converges trickle blood capillary tip, and this makes the skin at this position different
Often fragile and sensitive, eye pressure is excessive or sunlight is illuminated is all easy to damage eye skin for a long time.And these wounds
Evil would generally cause local inflammation, and if 5-lipoxygenase is the proinflammatory enzyme of inflammatory factor leukotriene, it is Semen arachidis hypogaeae
The Major Enzymes matter of tetraenoic acid pathways of inflammation, 5-lipoxygenase can promote the generation of leukotrienes material, and leukotriene is the strongest
One of strong inflammation courier, can cause the seepage of blood capillary and leukocyte, thus cause the inflammation such as local is red and swollen, itch.
Leukocyte elastase is a kind of serine protease that can cause tissue injury, can trigger inflammation mistake after tissue injury successively
Journey, leukocyte elastase also can decompose elastin and Collagen type IV albumen necessary to healthy skin, destroy skin
Elasticity and texture, in turn result in black eye, eye pouch and wrinkle etc..
The generation of existing eye skin-protection product mainly suppression tryrosinase and activity, the melanin that reduction has generated,
Accelerating the decomposition of tryrosinase, these can not be inherently eliminated black eye and desalination microgroove.The compositions that the present invention provides
Different from the mechanism of current eye skin-protection product, the compositions that the present invention provides is on the one hand by suppressing 5-lipoxygenase with white
The activity of cell elastase both proinflammatory enzymes, effective inflammation eliminated below eye and then fading are made because of inflammation
The symptoms such as black eye, eye pouch and the wrinkle become；On the other hand desalination is reached by eliminating free radical and supplementary skin nutrition
The effect of microgroove.
In the present invention, the primary efficacy of each raw material components is as follows:
Aesculus hippocastanum L. (Venocin) has another name called sal tree, hippocastanum, Aesculus etc..The fruit of this tree i.e. seed is referred to as horse
Chestnut or Semen Aesculi, be generally wrapped in peel in units of one to three.In Europe, Aesculus chinensis Bunge extract is traditional treatment
Varicosis, spider vein, hemorrhoid and relevant blood circulation disease or the medicine of chronic venous insufficiency (CVI), and
Carry out a large amount of clinical research.Varicosis, arachnoid vein, injury with blood-stasis, spot, black eye, cellulitis are had by Aesculus chinensis Bunge
Mitigation.
Algaroba seed extract can promote that hyaluronic acid is expressed, and for aquaporin and water-stop, has water and fills and water
Regeneration effect.Under stress, algaroba seed extract contributes to maintaining cellular morphology and cell adhesion, promotes and epidermal differentiation
The protein expression relevant with horny layer plasticity.Clinical proof, algaroba seed extract can promote skin hydration and skin gloss
Sense.It addition, it can also improve skin for self the adaptation ability under water deprivation stress.
Herba portulacae extract is natural botanical source, containing norepinephrine, linolenic acid, have antiinflammatory, irritation and
Antianaphylactic effect.
Cocoa extract contains theobromine and caffeine alkaloid, has defying age, antioxidation, effect of radiating vigour.
Astaxanthin has strong antioxidation, and it can effectively suppress free radical, suppress melanic generation, light
Change wrinkle, recover skin elasticity, lifting skin smoothness.
Water solublity ceramide is a kind of defying age and impaired renovation agent at sunshine, and its permeability is strong, has natural moisture preserving
Effect with protection skin corium integrity, additionally it is possible to reduce wrinkle.
Beta glucan has preferable film property, and it can help skin to keep moisture, has the laudatory title of stealthy skin.Its
There is anti-oxidation efficacy, it is possible to substantially reduce wrinkle of skin, improve skin elasticity；Protect the skin from the injury of ultraviolet, support
The tolerance of imperial environmental stimuli；Beta glucan can also give the use skinfeel that product is good, increases the Transdermal absorption of activity.
Decarboxylation carnosine has antioxidation, anti-saccharifying, the effect of revolution oxidation saccharification product, and it can also protect DNA, anti-color
Speckle, anti-light aging, uv-resistant B injure, and increase cell metabolism and recover cell viability, increase collagen protein and generate.It addition, decarboxylation
Carnosine also has the extracellular matrix effect of compacting, keeps skin to smooth, and suppresses inflammatory factor overreaction.
Cell growth factor stock solution can improve skin microcirculation, strengthens skin-nourishing supply, improves the colour of skin.Promote corium
The fibroblast synthesis of layer and secretion collagen protein, elastic fiber albumen and substrate, strengthen skin elasticity, effectively prevent wrinkle
Being formed, slowing down skin aging process, life-time service even can eliminate the shallow wrinkle of table.Cell growth factor stock solution supplemented with
Skin NMF, improves the dry and soft unsound skin such as coarse, matt, aging, makes skin more smooth, moistening, delicate.
Promote skin cell metabolism, accelerate melanin catabolism, reduce melanin and generate.
Lactobacillus/bear's weed fermented product extract has higher activity and more preferably skin-friendliness, can improve
Skin moisture-keeping, strengthens skin barrier performance, improves skin smoothness, make skin present younger, vigorous outward appearance.
Olibanum extract can remove black eye, Shu Min, antiinflammatory, defying age.
The present invention is by the activity of Olibanum extract suppression proinflammatory enzyme, thus eliminates the inflammation below eye；Europe
Continent extract can improve blood circulation, eliminates edema, provides the nutrition required for metabolism for skin, improves eye part skin
Aging state.Astaxanthin can suppress melanic formation, extra-nutrition, improves eye comfort level, thus reaches black eye
Circle effect.Decarboxylation carnosine and cell growth factor stock solution can increase cell metabolism and recover cell viability, increases collagen protein
Generate, improve the dry and soft unsound skin such as coarse, matt, aging, make skin more smooth, moistening, delicate.Water-soluble
Property ceramide have natural moisture preserving and protection skin corium integrity, have moisturizing defying age and reduce wrinkle produce work
With.Lactobacillus/bear's weed fermented product extract can strengthen skin screen protection barrier performance, improves skin smoothness.
The compositions that the present invention provides suppresses melanic formation by the activity of suppression proinflammatory enzyme, strengthens skin
Skin barrier, supplements eye part skin nutrition thus reaches the effect of black eye desalination microgroove.
As a kind of preferred version, described in go the compositions of black eye and desalination microgroove by the component of following mass percent
Composition:
Hyaluronate sodium 0.02～0.05%；Glycerol 2～5%；Butanediol 2～5%；Aesculus hippocastanum L. extract 1～
3%；Algaroba seed extract 1～2%；Herba portulacae extract 1～2%；Cer NS～10%；Beta glucan 2～10%；
Decarboxylation carnosine 1～5%；Cell growth factor stock solution 0.2～0.5%；Astaxanthin 0.5～1%；Cocoa extract 0.5～1%；
Olibanum extract 1～3%；Lactobacillus/bear's weed fermented product extract 1～3%；Preservative 0.2～0.5%；Surplus is water.
As a kind of preferred version, described in go the compositions of black eye and desalination microgroove by the component of following mass percent
Composition:
Hyaluronate sodium 0.05%；Glycerol 5%；Butanediol 5%；Aesculus hippocastanum L. extract 2%；Algaroba seed extract
1%；Herba portulacae extract 1%；Ceramide 4%；Beta glucan 4%；Decarboxylation carnosine 4%；Cell growth factor stock solution
0.3%；Astaxanthin 0.5%；Cocoa extract 1%；Olibanum extract 2%；Lactobacillus/bear's weed fermented product extract 3%；
Preservative 0.3%；Surplus is water.
The preparation method of the above-mentioned compositions removing black eye and desalination microgroove, described method comprises the steps:
S1: water, hyaluronate sodium, glycerol and butanediol are mixed and stirred for uniformly, is heated to 80～85 DEG C and makes each component
Dissolve, and be incubated 10～20 minutes；
S2: when the mixture temperature in S1 is reduced to 45～50 DEG C, adds other each component in compositions, and stirring is all
Even；When temperature of charge is reduced to 38～40 DEG C, filter discharging, black eye and the compositions of desalination microgroove must be gone.
Preferably, the mixing speed in S1 is 1400r/m；In S1 heating-up temperature be 80～85 DEG C with ensure each component dissolve
Completely, high temperature can also play the effect of sterilizing simultaneously.
The above-mentioned compositions application in eye skin-protection product removing black eye and desalination microgroove.
A kind of eye skin-protection product removing black eye and desalination microgroove, in described eye skin-protection product, above-mentioned goes black eye
And the consumption of the compositions of desalination microgroove is 1～10%.
Preferably, the consumption going the compositions of black eye and desalination microgroove described in is 6%.
Preferably, described eye skin-protection product is made up of the component of following mass percent:
0.1～0.3% AVC, 2～the propylene glycol of 5%, 0.2～0.5% propylene
The macadimia nut seed oil of acid hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers, 1～3% isononyl isononanoate, 1～3%, 1
～the dicaprylyl carbonate of 3%, go black eye and the compositions of desalination microgroove described in 1～10%, surplus is water.
It is further preferable that described eye skin-protection product is made up of the component of following mass percent:
The AVC of 0.25%, the propylene glycol of 5%, 0.5% 2-(Acryloyloxy)ethanol/
Sodium acryloyldimethyl taurate copolymers, the isononyl isononanoate of 3%, 3% macadimia nut seed oil, 3% carbonic acid two pungent
The compositions of ester, 1～10%, surplus is water.
In the present invention, conventional method of the prior art can be used to prepare the above-mentioned eye removing black eye and desalination microgroove
Portion's skin-protection product.
Compared with prior art, there is advantages that
On the one hand the compositions that the present invention provides is promoted by suppression 5-lipoxygenase and leukocyte elastase both
The activity of inflammatory reaction enzyme, black eye, eye pouch and the wrinkle that effective inflammation eliminated below eye and then fading cause because of inflammation
Etc. symptom；On the other hand reach to desalinate the effect of microgroove by eliminating free radical and supplementary skin nutrition.The present invention provides
Compositions suppress melanic formation by the activity of suppression proinflammatory enzyme, strengthen skin barrier, supplement eye skin
Skin nutrition thus reach black eye desalination microgroove effect.
Accompanying drawing explanation
The eye essence that Fig. 1 provides for application test example 2 go the compositions addition of black eye and desalination microgroove to going
The impact of black eye effect；
The eye essence that Fig. 2 provides for application test example 2 go the compositions addition of black eye and desalination microgroove with right
The impact of desalination microgroove effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.These embodiments are only that the typical case to the present invention retouches
State, but the invention is not restricted to this.Test method used in following embodiment if no special instructions, is conventional method, is made
Raw material, reagent etc., if no special instructions, be the raw material and reagent that can obtain from the routine commercial sources such as commercial.
A kind of make-up composition that can remove black eye and desalination microgroove, by the following raw material system of weight percentage
For forming:
Component A: hyaluronate sodium 0.01～0.05%, glycerol 1～5%, butanediol 1～5%, the deionized water of surplus；
B component: Aesculus hippocastanum L. extract 1～10%, algaroba seed extract 0.5～10%, Herba portulacae extract 0.5
～10%, Cer EOS～10%, beta glucan 1～10%, decarboxylation carnosine 1～10%, cell growth factor stock solution 0.1～
1%, astaxanthin 0.1～2%, cocoa extract 1～10%, Olibanum extract 1～10%；Lactobacillus/bear's weed fermentation
Extract 1～10%, preservative 0.2～1%.
Embodiment 1～14: a kind of compositions removing black eye and desalination microgroove
Take the following raw material in terms of weight/mass percentage composition respectively:
Component A: hyaluronate sodium 0.05%, glycerol 5%, butanediol 5%, the water of surplus；
In B component, preservative is 0.6%, and the concrete proportioning of other composition sees below Tables 1 and 2.
The formula of B component in the compositions that table 1 embodiment 1～7 provides
The formula of B component in the compositions that table 2 embodiment 8～14 provides
The formula of B component in the compositions that table 3 reference examples 1～7 provides
The preparation method of the above-mentioned compositions removing black eye and desalination microgroove is as follows:
(1) according to formula ratio the deionized water in component A, hyaluronate sodium, glycerol, butanediol added and mix in pot,
It is heated with stirring to 80～85 DEG C, stirs speed for 1400r/m；
(2) the component A raw material dissolved is cooled to 45～50 DEG C, then by the raw material of B component in formula according to formula
Middle mass ratio adds in agitated kettle, stirs, and stirs speed constant；
(3) temperature of the mixture in (2) is reduced to when 38～40 DEG C filter discharging, and black eye and desalination must be gone thin
The compositions of stricture of vagina.
Application test example 1 removes security test and the efficacy test of the compositions of black eye and desalination microgroove
(1) security test
Choose 14 black eye and the eye person that has microgroove is as voluntary tester, do comparison test with right and left eyes, be coated with every day
Compositions in the most each embodiment, the eye part skin reacting phenomenon after record 8h, 12h.
The using method of above-mentioned each compositions is as follows:
Dipping eye cream small rice grain size with the third finger, first tap in side now, left hand is lightly by past for the lower eyelid of eye
More drop-down, then do annular massage gently along inner eye corner, upper eyelid, eye tail, lower eyelid, about generally 4～5 circles；Finally
Again with the third finger of two handss, corresponding eyes, particularly eye pouch part are clapped in place gently, allow skin fully absorb.
Result shows: after being coated with compositions 8h in various embodiments of the present invention, 12h, has no that the allergy such as eye part skin is rubescent are anti-
Should, illustrate that product of the present invention goes black eye desalination microgroove compositions to be safe, there is no any bad phenomenon.
(2) efficacy test
Subject Population: eye has the people of black eye and microgroove to participate in experiment test, totally 21 people
Method of testing:
Test sites is the eye socket skin having black eye and microgroove.Adhering to every day sooner or later using, using method, with (1), is held
Continuous use 14 days, and respectively these 14 experimenters persistently used the 0th day, the 7th day, the eye black eye colourity of the 14th day and
The situation desalinating microgroove after 14th day is tested, and other 7 people carry out test test by the one in above-mentioned 7 groups of reference examples respectively
Result such as following table.
Table 4 embodiment 1～14 and the performance test of compositions that provides of reference examples 1～7
General Asian skin colours's colourity is close to 6, from upper table 1, in each embodiment, the colourity of test all close to 6, this
Show that the compositions removing black eye and desalination microgroove that various embodiments of the present invention prepare has and preferably go black-eyed effect
Really；By contrast, each reference examples go black-eyed effect poor.Meanwhile, the combination in each embodiment that the present invention provides
Thing also has the effect preferably desalinating microgroove.
Application test example 2 one kinds removes black eye and the eye essence of desalination microgroove
A kind of eye essence removing black eye and desalination microgroove, this elite is by the following raw material system of weight percentage
For forming:
The AVC of 0.25%, the propylene glycol of 5%, 0.5% 2-(Acryloyloxy)ethanol/
Sodium acryloyldimethyl taurate copolymers, the isononyl isononanoate of 3%, the macadimia nut seed oil of 3%, the carbonic acid two of 3% is pungent
Ester, 1～10% embodiment 1 provide compositions, surplus is deionized water.
The preparation method of described eye essence uses conventional method of the prior art to be prepared from.
Fig. 1 is the addition of the compositions removing black eye and desalination microgroove in the eye essence shadow to going black eye effect
Ring, Fig. 2 be in eye essence the addition of compositions for desalinate microgroove impact.
As seen from Figure 1, Figure 2, when the addition of the compositions in eye essence is 6%, go black eye desalination microgroove effect
Fruit is optimal.It follows that the compositions that the present invention provides can suppress the activity of two kinds of proinflammatory enzymes effectively, eliminate eye
Portion's skin inflammation, removes free radical, nutrition skin, reaches the effect of black eye desalination microgroove.
For a person skilled in the art, can technical scheme as described above and design, make other
Various corresponding changes and deformation, and all these change all should belong to the claims in the present invention protection domain it
In.
Claims (8)
1. one kind go black eye and desalination microgroove compositions, it is characterised in that described in go black eye and desalination microgroove combination
Thing is made up of the component of following mass percent:
Hyaluronate sodium 0.01～0.05%；Glycerol 1～5%；Butanediol 1～5%；Aesculus hippocastanum L. extract 1～10%；Algaroba
Seed extract 0.5～10%；Herba portulacae extract 0.5～10%；Cer EOS～10%；Beta glucan 1～10%；Decarboxylation carnosine 1
～10%；Cell growth factor stock solution 0.1～1%；Astaxanthin 0.1～2%；Cocoa extract 1～10%；Olibanum extract 1～
10%；Lactobacillus/bear's weed fermented product extract 1～10%；Preservative 0.2～1%, surplus is water.
Go black eye and the compositions of desalination microgroove the most according to claim 1, it is characterised in that described in go black eye and light
The compositions changing microgroove is made up of the component of following mass percent:
Hyaluronate sodium 0.02～0.05%；Glycerol 2～5%；Butanediol 2～5%；Aesculus hippocastanum L. extract 1～3%；Algaroba
Seed extract 1～2%；Herba portulacae extract 1～2%；Cer NS～10%；Beta glucan 2～10%；Decarboxylation carnosine 1～5%；
Cell growth factor stock solution 0.2～0.5%；Astaxanthin 0.5～1%；Cocoa extract 0.5～1%；Olibanum extract 1～3%；Breast
Acidfast bacilli/bear's weed fermented product extract 1～3%；Preservative 0.2～0.5%；Surplus is water.
Go black eye and the compositions of desalination microgroove the most according to claim 1, it is characterised in that described in go black eye and light
The compositions changing microgroove is made up of the component of following mass percent:
Hyaluronate sodium 0.05%；Glycerol 5%；Butanediol 5%；Aesculus hippocastanum L. extract 2%；Algaroba seed extract 1%；Dens Equi
Herba Amaranthi tricoloris extract 1%；Ceramide 4%；Beta glucan 4%；Decarboxylation carnosine 4%；Cell growth factor stock solution 0.3%；Astaxanthin 0.5%；
Cocoa extract 1%；Olibanum extract 2%；Lactobacillus/bear's weed fermented product extract 3%；Preservative 0.3%；Surplus is water.
4. claims 1 to 3 arbitrary described in go black eye and the preparation method of compositions of desalination microgroove, it is characterised in that institute
The method of stating comprises the steps:
S1: water, hyaluronate sodium, glycerol and butanediol are mixed and stirred for uniformly, is heated to 80～85 DEG C and makes each component dissolve,
And it is incubated 10～20 minutes；
S2: when the mixture temperature in S1 is reduced to 45～50 DEG C, adds other each component in compositions, stirs；
When temperature of charge is reduced to 38～40 DEG C, filter discharging, black eye and the compositions of desalination microgroove must be gone.
5. claims 1 to 3 arbitrary described in go black eye and the compositions application in eye skin-protection product of desalination microgroove.
6. the eye skin-protection product removing black eye and desalination microgroove, it is characterised in that in described eye skin-protection product, right
The consumption going the compositions of black eye and desalination microgroove described in requirement 1～3 is arbitrary is 1～10%.
Remove black eye and the eye skin-protection product of desalination microgroove the most according to claim 6, it is characterised in that described eye protects
Skin product is made up of the component of following mass percent:
0.1～0.3% AVC, 2～the propylene glycol of 5%, 0.2～0.5% acrylic acid hydroxyl second
Macadimia nut seed oil, 1～the carbon of 3% of ester/sodium acryloyldimethyl taurate copolymers, 1～3% isononyl isononanoate, 1～3%
Dioctyl phthalate, going black eye and the compositions of desalination microgroove described in 1～10%, surplus is water.
Remove black eye and the eye skin-protection product of desalination microgroove the most according to claim 7, it is characterised in that described eye protects
Skin product is made up of the component of following mass percent:
The AVC of 0.25%, the propylene glycol of 5%, 0.5% 2-(Acryloyloxy)ethanol/acryloyl two
N-methyltaurine sodium copolymer, the isononyl isononanoate of 3%, the macadimia nut seed oil of 3%, the dicaprylyl carbonate of 3%, go described in 6%
Black eye and the compositions of desalination microgroove, surplus is water.
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| CN201610881269.4A CN106309349B (en) | 2016-09-30 | 2016-09-30 | A kind of composition and its preparation method and application for going black eye and desalinating microgroove |
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| CN201610881269.4A CN106309349B (en) | 2016-09-30 | 2016-09-30 | A kind of composition and its preparation method and application for going black eye and desalinating microgroove |
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| CN107184411A (en) * | 2017-04-21 | 2017-09-22 | 韩后化妆品股份有限公司 | A kind of preparation method of the tender factor of Compound Water, cosmetics and cosmetics |
| CN107260569A (en) * | 2017-05-25 | 2017-10-20 | 珀莱雅化妆品股份有限公司 | A kind of preparation method of eye-care compositions liposome |
| CN107737031A (en) * | 2017-11-23 | 2018-02-27 | 上海合轩品牌管理有限公司 | A kind of ight pad pasting compositions useful of Vitamin K and preparation method thereof |
| CN110179735A (en) * | 2019-07-10 | 2019-08-30 | 湖北省吉美化妆品有限公司 | Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care |
| CN110403872A (en) * | 2019-08-29 | 2019-11-05 | 湖北省麦诗特生物科技有限公司 | A kind of preparation method and application of the bear's weed tunning extract with moisture-keeping efficacy |
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| CN111617023A (en) * | 2020-07-14 | 2020-09-04 | 北昊干细胞与再生医学研究院有限公司 | Eye composition and preparation method thereof |
| CN111991286A (en) * | 2020-08-20 | 2020-11-27 | 上海致新生物科技有限公司 | Eye cream composition for fading fine wrinkles and preparation method thereof |
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| CN107184411A (en) * | 2017-04-21 | 2017-09-22 | 韩后化妆品股份有限公司 | A kind of preparation method of the tender factor of Compound Water, cosmetics and cosmetics |
| CN107260569A (en) * | 2017-05-25 | 2017-10-20 | 珀莱雅化妆品股份有限公司 | A kind of preparation method of eye-care compositions liposome |
| CN107737031A (en) * | 2017-11-23 | 2018-02-27 | 上海合轩品牌管理有限公司 | A kind of ight pad pasting compositions useful of Vitamin K and preparation method thereof |
| CN110179735A (en) * | 2019-07-10 | 2019-08-30 | 湖北省吉美化妆品有限公司 | Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care |
| CN110403872A (en) * | 2019-08-29 | 2019-11-05 | 湖北省麦诗特生物科技有限公司 | A kind of preparation method and application of the bear's weed tunning extract with moisture-keeping efficacy |
| CN111529455A (en) * | 2020-06-18 | 2020-08-14 | 广州鹰远生物科技有限公司 | Multi-effect washing and protecting composition and application thereof |
| CN111617023A (en) * | 2020-07-14 | 2020-09-04 | 北昊干细胞与再生医学研究院有限公司 | Eye composition and preparation method thereof |
| CN111991286A (en) * | 2020-08-20 | 2020-11-27 | 上海致新生物科技有限公司 | Eye cream composition for fading fine wrinkles and preparation method thereof |
| CN112353725A (en) * | 2020-11-19 | 2021-02-12 | 广州领衔生物科技有限公司 | Efficacy composition in eye cream, eye cream and preparation method thereof |
| CN112494384A (en) * | 2020-12-09 | 2021-03-16 | 珠海为你而美丽化妆品有限公司 | Composition for removing dark eye circles, eye mask and preparation method of eye mask |
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