CN109893464A - It is a kind of to block the whitening spot-removing skin care item and preparation method thereof for inhibiting reduction melanin - Google Patents

Abstract

The present invention relates to a kind of whitening spot-removing skin care item and preparation method thereof for blocking and inhibiting to restore melanin, more particularly to the one kind has blocking, inhibit, restore the whitening spot-removing prescription of melanin, the prescription is by niacinamide, glycine betaine, beta glucan, Radix Cynanchi Atrati extract, Cortex Mori extract, overlay film saccharomycetes to make fermentation Product filtrate, Bo Nate spirulina extract, chlorella extract, rice germ extracts, Maltsupex, the composition such as wheat malt extract, blocking can be played, inhibit, restore melanin, accelerate cell metabolism, accelerate melanin horn cell to fall off；Skin ageing phenomenon is eliminated, inhibits, delay and reduces wrinkle generation, the skin condition of skin regeneration is promoted to act on；Skin care item of the invention are not limited by product forms, can be made an addition to aqua, lotion, cream, essence etc., be can be used in multiple use, and the obvious shortcoming that commercial product has a single function is compensated for.

Description

It is a kind of to block the whitening spot-removing skin care item and preparation method thereof for inhibiting reduction melanin

Technical field

The present invention relates to a kind of skin care item more particularly to it is a kind of block inhibit reduction melanin whitening spot-removing skin care item and Preparation method.

Background technique

Liking to be beautiful is the nature of the people of the world, and for the Asia women partially yellow to the colour of skin, " beauty " often be unable to do without " white ", common saying It all says " a white screening three is ugly ", describes often to use when people's U.S., " white touched with red ", " skin smooth like lard ", " white matter is revealed " etc. are described The white and tender fine word of skin.However as the deterioration of environment, the radiation of ultraviolet light, the growth at age, the pollution of tail gas, skin Skin is encroached at first, water shortage, saccharification, obscure, sensitive, long spot, relaxation, general red, the nursing that skin has needed in a hurry.Mesh Most of the cosmetics of preceding use have that effect is indefinite and certain adverse reaction occur, and people, which are highly desirable to, has effect Fruit is clear, act on by way of multiplicity, safely, the blocking that has no adverse reaction inhibit the whitening spot-removing skin care item of reduction melanin.This hair It is bright to be mentioned by adding niacinamide, glycine betaine, beta glucan, radix cynanchi atrati (CYNANCHUM ATRATUM) in being formulated in moisturizing is formulated Take object, mulberry (MORUS ALBA) bark extract, overlay film saccharomycetes to make fermentation Product filtrate, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) extract, rice (ORYZA SATIVA) germ extracts, Barley (HORDEUM VULGARE) bud extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, sea-buckthorn (HIPPOPHAE RHAMNOIDES) fruit are extracted Object, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS-IDAEA) leaf extract, purslane (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, Adenosine, palmityl tetrapeptide -7, allantoin, silantriol, hyaluronic acid at subassembly, extend the function of product, Ji Nengbao It is wet and whitening and can releive；Simultaneously because this is water solubility at subassembly, so not limited by product forms, can make an addition to Aqua, lotion, cream, essence etc..

Summary of the invention

The purpose of the present invention is to solve the above problems, and provide a kind of definite effect, purposes multiplicity, safety, invariably The blocking of good reaction inhibits the whitening spot-removing skin care item and preparation method thereof of reduction melanin.

To achieve the goals above, the present invention adopts the following technical scheme:

It is a kind of to block the whitening spot-removing skin care item for inhibiting reduction melanin, including have block below, inhibit, restores black The whitening spot-removing component of element effect: niacinamide, glycine betaine, beta glucan, Radix Cynanchi Atrati extract, Cortex Mori extract, overlay film yeast Bacterium tunning filtrate, Bo Nate spirulina extract, chlorella extract, rice germ extracts, Maltsupex, wheat Bud extract, Wild soybean bud extract, sesame bud extract, seabuckthorn fruit extract, tomato berry extract, pomegranate berry extract, Blueberry leaf extract, purslane extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, silantriol, hyalomitome Acid.

Further, described that there is blocking, inhibit, the whitening spot-removing component of reduction melanin effect is blocking inhibition reduction Weight percent in the whitening spot-removing skin care item of melanin are as follows: niacinamide 1~6%, glycine betaine 0.75~4.5%, beta glucan 0.75~4.5%, Radix Cynanchi Atrati extract 0.5~3%, Cortex Mori extract 0.5~3%, overlay film saccharomycetes to make fermentation Product filtrate 0.5 ~3%, Bo Nate spirulina extract 0.0075~0.045%, chlorella extract 0.0075~0.045%, rice plumule mention Take object 0.0075~0.045%, Maltsupex 0.0075~0.045%, wheat malt extract 0.0075~0.045%, Wild soybean bud extract 0.0075~0.045%, sesame bud extract 0.0075~0.045%, seabuckthorn fruit extract 0.0075 ~0.045%, tomato berry extract 0.0075~0.045%, pomegranate berry extract 0.0075~0.045%, blueberry leaf extract Object 0.0075~0.045%, purslane extract 0.125~0.75%, dipotassium glycyrrhizinate 0.125~0.75%, adenosine 0.125 ~0.75%, palmityl tetrapeptide -7 0.125~0.75%, allantoin 0.125~0.75%, EPIDERMOSIL 0.125~ 0.75%.

Further, described that there is blocking, inhibit, the whitening spot-removing component of reduction melanin effect is blocking inhibition reduction Weight percent in the whitening spot-removing skin care item of melanin are as follows: niacinamide 4%, glycine betaine 3%, beta glucan 0.03%, radix cynanchi atrati Extract 0.1%, Cortex Mori extract 2%, overlay film saccharomycetes to make fermentation Product filtrate 2%, Bo Nate spirulina extract 0.03%, chlorella extract 0.03%, rice germ extracts 0.03%, Maltsupex 0.03%, wheat malt extract 0.03%, Wild soybean bud extract 0.03%, sesame bud extract 0.03%, seabuckthorn fruit extract 0.03%, tomato fruit are extracted Object 0.03%, pomegranate berry extract 0.03%, blueberry leaf extract 0.03%, purslane extract 0.5%, dipotassium glycyrrhizinate 0.5%, adenosine 0.5%, palmityl tetrapeptide -7 0.5%, allantoin 0.5%, EPIDERMOSIL 0.5%.

Further, described that there is blocking, inhibit, the whitening spot-removing component of reduction melanin effect is blocking inhibition reduction Weight percent in the whitening spot-removing skin care item of melanin are as follows: niacinamide 3%, glycine betaine 2.25%, beta glucan 0.0225%, Radix Cynanchi Atrati extract 0.075%, Cortex Mori extract 1.5%, overlay film saccharomycetes to make fermentation Product filtrate 1.5%, Bo Nate spirulina Extract 0.0225%, chlorella extract 0.0225%, rice germ extracts 0.0225%, Maltsupex 0.0225%, wheat malt extract 0.0225%, Wild soybean bud extract 0.0225%, sesame bud extract 0.0225%, sand Spine berry extract 0.0225%, tomato berry extract 0.0225%, pomegranate berry extract 0.0225%, blueberry leaf extract 0.0225%, purslane extract 0.375%, dipotassium glycyrrhizinate 0.375%, adenosine 0.375%, palmityl tetrapeptide -7 0.375%, allantoin 0.375%, EPIDERMOSIL 0.375%.

Further, described that there is blocking, inhibit, the whitening spot-removing component of reduction melanin effect is blocking inhibition reduction Weight percent in the whitening spot-removing skin care item of melanin are as follows: niacinamide 2%, glycine betaine 1.5%, beta glucan 0.015%, white Common vetch extract 0.05%, Cortex Mori extract 1%, overlay film saccharomycetes to make fermentation Product filtrate 1%, Bo Nate spirulina extract 0.015%, chlorella extract 0.015%, rice germ extracts 0.015%, Maltsupex 0.015%, wheat malt mention Take object 0.015%, Wild soybean bud extract 0.015%, sesame bud extract 0.015%, seabuckthorn fruit extract 0.015%, kind Solanberry extract 0.015%, pomegranate berry extract 0.015%, blueberry leaf extract 0.015%, purslane extract 0.25%, Dipotassium glycyrrhizinate 0.25%, adenosine 0.25%, palmityl tetrapeptide -7 0.25%, allantoin 0.25%, EPIDERMOSIL 0.25%.

Further, described that there is blocking, inhibit, the whitening spot-removing component of reduction melanin effect is blocking inhibition reduction It include silantriol and hyaluronic acid, the silantriol in the EPIDERMOSIL in the whitening spot-removing skin care item of melanin It is 90~100:1~10 with hyaluronic acid ratio.

It is a kind of to block the preparation method for inhibiting the whitening spot-removing skin care item of reduction melanin, which is characterized in that including as follows Step:

(1) various raw materials in precise formula are held with vessel that are clean and disinfecting；

(2) oily phase pot, side is added in polymethyl methacrylate, PEG-60 rilanit special, octyl dodecanol polyethers -16 Stirring side is warming up to 80 DEG C~85 DEG C, is uniformly mixed it, keeps the temperature 10 minutes；

(3) by water, dipropylene glycol, glycerol, glycerin polyether -26, polyethylene glycol -32, double-PEG-18 methyl ether dimethyl-silicons Alkane, glucomannans, Sodium Hyaluronate, EDETATE SODIUM, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, Water phase pot is added in parahydroxyacet-ophenone, and warming while stirring makes it dissolve sufficiently to 85 DEG C~90 DEG C, keeps the temperature 10 minutes；

(4) water phase pot mixture is first pumped into 75~85 DEG C, then slowly takes out oily phase pot mixture by preheating emulsion pot Enter, emulsifying 15~30 minutes, keeps the temperature 20 minutes；

(5) 45 DEG C are cooled to, water, glycerol, 1,2- hexylene glycol, 1,2- pentanediol, beta glucan, butanediol, radix cynanchi atrati is added It is extract, Cortex Mori extract, overlay film saccharomycetes to make fermentation Product filtrate, propylene glycol, caprylic/capric triglyceride, butanediol, double It is third glycol, 1,2- pentanediol, lecithin, glycerol, Bo Nate spirulina extract, chlorella extract, rice germ extracts, big Malt extract, wheat malt extract, Wild soybean bud extract, sesame bud extract, seabuckthorn fruit extract, tomato fruit are extracted Object, pomegranate berry extract, blueberry leaf extract, purslane extract, EPIDERMOSIL, niacinamide, glycine betaine, glycyrrhizic acid two Potassium, adenosine, palmityl tetrapeptide -7, allantoin, tromethamine, 1,3- propylene glycol, decoyl hydroximic acid, 1,2- hexylene glycol, pungent glycol, Sensiva SC50, Phenoxyethanol, essence, and be sufficiently stirred；

(6) 38 DEG C are cooled to, is discharged, is stood；

(7) after the assay was approved, filling, packaging, coding, storage are stand-by.

Niacinamide is also known as vitamin B3, as a kind of medical components have very high safety and clinic skin The basic vitamins replenishers of one of section's treatment, are ready for use on treatment photosensitive dermatitis, acne etc. relatively broadly.In recent years Come research have shown that, it inhibit melanin pigmentation, in terms of also have good curative effect；Based on this feature, niacinamide Further extension has been obtained in the application of cosmetic field, other than traditional whitening effect, also be used to reduce raw At the melanin of, precipitating, its transfer to cells of superficial layer is obstructed, accelerate that cell metabolism, to accelerate melanin horn cell de- It falls.Niacinamide is able to maintain that skin water content, promotes skin corium microcirculation.Niacinamide can also greatly reduce or to eliminate skin old Change phenomenon, for example wrinkle, peeling, pore are coarse etc., reduce injury of the free radical to skin, play pre- anti-aging, repair skin The effect obscure with face is reduced.

Glycine betaine is the moisturizing ingredient extracted from beet root, which is easy and water phase interaction, generates moisturizing Ability.Glycine betaine has an outstanding moisture-retaining capacity, and using when there is no the feeling of sticky paste.Face can be made more smooth after use, And the combination of it and other compositions can be used for mitigating skin allergy, be ideal calm moisturizer.It can statocyte infiltration Pressure, skin meet with adverse circumstances, Premeabilisation of cells pressure is unbalance, cell dehydration when helper cell reply balance and moisturizing state.

Beta glucan is the natural polysaccharides being present in oat, barley, wheat, yeast and fungi, always for a long time It is considered as the nonspecific stimulant in immune system, it will usually cause macrophage activation.In the past twenty years, β-Portugal The effect of glycan stimulating human body immune system has been found.1991, Czop and coworkers identify β-(1, 3) oligosaccharide in-D- glucan series is specific Macrophage Surface receptor.Beta glucan promotes fibroblast and angle The migration for changing cell has the function of promoting wound healing, the activation of stimulating expression of macrophage, i.e., with sensitive increase skin of releiving The effect of skin immunity, the skin care that moisturizing can be applied to, releived.The Radican (I) bought to RADINT company

The effect of radix cynanchi atrati (CYNANCHUM ATRATUM) extract can remarkably promote angle for that can promote skin regeneration Matter forms the migration and update of cell, shows the extraordinary curative effect for promoting wound healing, has good anti-inflammatory, anti-thorn Swash effect, there is the curative effect for promoting wound healing well.Tradition application is upper, and radix cynanchi atrati can be with fall fire, therefore can be after typhoid fever Phase or postpartum consume energy and blood of human body and body fluid and internal low fever has a fever after not weakening and curing physical fatigue symptom, due to lung heat Caused cough, useless fellow, malignant sore, sphagitis, is used diuresis on wound that snake stings.In skin care, related to inflammatory reaction The growth of the factor hinders in the research of effect, and radix cynanchi atrati (CYNANCHUM ATRATUM) extract is to IL-1 (Interleukin-1) Growth have an apparent inhibitory effect, i.e., radix cynanchi atrati (CYNANCHUM ATRATUM) extract has good anti-inflammatory effect of releiving Fruit.The HI-CLERA bought to RADINT company

Mulberry (MORUS ALBA) bark extract can inhibit the enzymatic activity of tyrosinase, there is skin-whitening outstanding Effect.And the antioxidant effect of mulberry (MORUS ALBA) bark extract can prevent UV-induced pigmentation phenomenon And skin cell damage, and antibacterial, antiphlogistic effects are also very outstanding, and it can effective calm various skins excessive internal heats.Mulberry (MORUS ALBA) bark extract can inhibit the formation of melanin to have outstanding whitening effect, and mulberry (MORUS ALBA) bark extracts Object can absorb UV-B (280~320 nanometers) field for causing sunburn, absorb the extensive neck in the field UV-A (320~400m) Domain.Mulberry (MORUS ALBA) bark extract can anti-harmful light, while there is prevention skin aging, prevention black mole, freckle etc. Function, mulberry (MORUS ALBA) bark extract is good whitening raw materials.

Overlay film saccharomycetes to make fermentation Product filtrate is wherein protein, nucleic acid, vitamin etc. will to extract product after broken wall.It should Various nutritional ingredient cel l proliferations in ingredient natural amino acid rich in, are able to suppress tyrosinase activity, from And reach inhibition melanin, have the function that whitening, long-acting moisturizing and accelerated ageing corneocyte update.

Bo Nate spirulina is the green black colour microorganism containing various nutrients, in World Health Organization (WHO) and joint State's grain<food>and agricultural organization (UNFAO) are appointed as the following grain, US National Aeronautics and Space Administration (NASA) and Japan's boat Empty space research is chosen to be " universe food ".SOD contains 11,000Unit, Bo Nate in every 100g in Bo Nate spirulina Spirulina is on earth than any cereal, and vanilla is all containing more rich and varied nutrients, including vegetable protein, various dimensions His life, minerals necessary fatty acid, phytochrome, SOD etc. are very brilliant to the white-skinned face function of skin.Bo Nate spirulina (SPIRULINA PLATENSIS) extract is to extract product in Bo Nate spirulina, in skin care can moisturizing, make its richness Flexible, the soft and smooth water of moisturizing is tender, while providing nutritional ingredient for skin, desalinates obscure phenomenon, keeps skin youth vibrant.Bead Algae (chlorella) belongs to green algae, the SOD containing white-skinned face function, can be by DOPA quinone, the 5.6- bis- in melanin synthesis process The intermediate reductions such as oxyindole, 5.6- dihydroindole -2- carboxylic acid are at DOPA and dopachrome, to inhibit the shape of pigment granule At.With feature is inhibited tyrosinase activity, melanin can be made to take off by the adjacent benzene diquinone construction recovery of melanin at phenolic structure Color can make oxidisability melanin be reduced to colourless reproducibility melanin.Its photosynthetic performance power and numerous identical as higher plant Grow that ability is very strong, as long as having certain solar radiation and nutrition that can rise to 100 times in 10 days.Chlorella A kind of pure natural product that (CHLORELLA VULGARIS) extract is extracted by chlorella has and promotes collagen and elastic force Albumen synthesis, increases skin elasticity and compact sense, can be used for dispelling striae of pregnancy, eliminates fat line and obscure product, has good Moisturizing and conditioning skin effect.Germination rice is the food of anti-oxidant brilliance, and inhibitory activity oxygen is generated in germination process Antioxidase SOD.Increase the activity that zinc concentration improves SOD especially in germination, it is also rich in plumule to tie up him B1 is ordered, all having will be in DOPA quinone, 5.6- dihydroxy indole, 5.6- dihydroindole -2- carboxylic acid in melanin synthesis process etc. Mesosome is reduced into the ability of DOPA and dopachrome, to inhibit the formation of pigment granule.With inhibiting tyrosinase activity spy Sign, can make melanin fade, oxidisability melanin can be made to be reduced to by the adjacent benzene diquinone construction recovery of melanin at phenolic structure Colourless reproducibility melanin.Rice (ORYZA SATIVA) germ extracts are the products of the extract from rice plumule, are facilitated The soft and moist degree of skin is improved, wherein the activity and vitamin of SOD abundant, have anti-oxidant, skin whitening tune in skin care Reason effect, can be intermediate by DOPA quinone, 5.6- dihydroxy indole, 5.6- dihydroindole -2- carboxylic acid in melanin synthesis process etc. Body is reduced into DOPA and dopachrome, to inhibit the formation of pigment granule.It, can will be black with inhibiting tyrosinase activity feature The adjacent benzene diquinone construction recovery of pigment makes melanin fade at phenolic structure, and oxidisability melanin can be made to be reduced to colourless go back Originality melanin.The content of the SOD of fructus hordei germinatus: active unit 110,111~310,000/100g, the chlorophyll of fructus hordei germinatus contain Amount: 1600 times of spinach, contain a large amount of SOD and chlorophyll by 2400 times of collard in fructus hordei germinatus, whitening effect is significant, The content beta-carotene of fructus hordei germinatus: 5511ug (this be 600 times of cabbage, 3 times of collard), the vitamin of fructus hordei germinatus C content: contain 328.8mg in 100g.Barley (HORDEUM VULGARE) bud extract is the production of the extract from fructus hordei germinatus Object, wherein SOD active constituent abundant and Vitamin C activity ingredient have, good skin is anti-oxidant, whitening effect.Wheat malt In SOD rich in, be not only whitening, it is anti-aging, also have extraordinary effect to hereditary atopic dermatitis.Wheat (TRITICUM VULGARE) bud extract is that extract is product from wheat malt, preferable to fibrous bud cel l proliferation, Show preferable skin-active Antiageing effect；Inhibition to Collagenase and the elimination effect to DPPH, the nutritional ingredient contained have Enhance human metabolism, adjustment nervous function, it is smooth to play skin delicacy, inhibits, wrinkle is delayed to generate；It is thin to B-16 Cytoactive has inhibition, and rejection ability is more weaker than arbutin, but also has the function of skin whitening.Soya bean can help new old generation It thanks, containing various enzymes, blood can be made peace and quiet, healthy blood vessel desalinates will, beautifying skin.There is extraordinary skin resurfacing effect To the pre- anti-aging highly significant of skin, skin-nourishing is attacked, skin clear and transparent is maintained to moisten.The protein of soya bean is high-quality Protein prevents the generation of will, and helpful to blood circulation containing abundant vitamin e, also there is brilliant effect to senile plaque. Wild soybean (GLYCINE SOJA) bud extract is that extract is product from Wild soybean bud, can promote the life of fiber sprout cell It is long, there is skin-active, the effect of anti-aging, while being able to maintain the moisture of skin, Saccharideisomerate.Contain the spy of lignan in sesame Very (lignan) ingredient, it is existed in the form of sesamin, sesamolin.The anti-oxidation efficacy of sesamin is to be recognized by people Card, can improve wrinkle of skin.Vitamin e content in sesame is higher than other cereal, and the ingredient of fiber and calcium is abundant, can be to prevent Only skin aging can effectively treat callosity.The ovum of Phospholipids, phosphatide is abundant to can be enhanced skin resistance, can prevent old Change, having improves will, the effect of wrinkle.Sesame (SESAMUM INDICUM) bud extract is the product extracted from sesame bud, mistake The dysfunction of oxidase activation receptor (PPAR) is many diseases, a key factor including scytitis, sesame (SESAMUM INDICUM) bud extract shows the activation of PPAR to promote the proliferation of bud fibrocyte, tool with anti-inflammatory properties There is skin-active, also play the role of inhibition to tyrosinase, whitening agent can be made in cosmetics.Seabuckthorn tree is called vitamin Tree, in dead soil and Extreme drought, it is the current world that air Temperature Difference is big, which to wait a kind of shrub that can also be grown in mal-conditions, On the precious nonwood forest trees containing natural vitamin most species, be considered containing in the vitamin tree of " vitamin treasure-house " The beneficial active material of 100 kinds of human bodies.Its fruit is also known as fructus hippophae, sour bur, and ascorbic content is significantly larger than fresh dates and Mi Monkey peach, so that it is known as the treasure-house of natural vitamin, it is full of nutrition.Sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract is The product extracted from fructus hippophae contains various vitamin amino acids, SOD, flavonoids, unsaturated fatty acid, minerals etc. Rich in Multiple components, 5 kinds of vitamins abundant are especially rich in, white-skinned face function is widely known for these vitamin ingredients.To gold Proteases also have good inhibiting effect, and the activation of metalloproteinases is an index of skin aging, in conjunction with to super oxygen from By the elimination of base, show the function of having anti-ageing；Has the function of antibacterial anti-inflammatory simultaneously.1 glass of tomato juice of SOD content exists 4800unit, the blacking up red of black tomato is higher than general tomato antioxidant content of material, to white-skinned face function brilliance.The β-of black tomato Carrotene (β-carotene), the antioxidant content of lycopene (lycopene) etc. it is higher than general tomato content, cellulosic It is abundant.Tomato (SOLANUM LYCOPERSICUM) berry extract is the product extracted from black tomato fruit, has good beauty White skin lightening effect.Tomato (SOLANUM LYCOPERSICUM) berry extract is to the proliferation function of epidermal keratinocyte and to tissue The activation of protease shows that skin cell metabolism can be enhanced have Antiageing effect；There is activation to make luciferase element With illustrating there is anti-inflammatory；There is certain inhibiting effect to aromatase enzyme, can be used for preventing and treating because Corticosteroids are improper or cosmetics use It is improper and occur estrogen extremely increase the case where.Pomegranate has anti-oxidation efficacy abundant, is poison expelling and beautifying new trend, and new Mas' whitening or anti-aging care program.It can be the extra residual toxin of bride's skin venting with pomegranate beauty, to absorb battalion Feeding essence establishes better basis.Pomegranate (PUNICA GRANATUM) berry extract is the product extracted from pomegranate fruit, to B- 16 melanocyte activities show strong inhibition, are good cosmetics whitening additives, have to skin-whitening good Effect also has good lipoid peroxidization resistant, can play delaying senility function.Cowberry ericad originates in north Beauty, it is widely distributed regional from the arctic to tropical alpine on the Northern Hemisphere, containing having anthocyanin, pectin, tannin, arbutin, dimension life The Multiple components such as plain C and B family vitamin see ingredient it is known that its effect multiplicity is effective.Cranberry contains abundant nutrition, Including Multiple components such as anthocyanin, pectin, tannin, arbutin, vitamin C and B family vitamins, wherein bioactive ingredients are main It is colored glycosides.Its main component has natural visual purple (Rhodopsin) and flavonoids (Flavonoid).Also containing rich in blueberry leaf Rich arbutin ursolic acid, blueberry (VACCINIUM VITIS-IDAEA) leaf extract is the product extracted from cowberry leaf, tool There is brilliant white skin, promotes texture of skin and other effects.The RA-EX Liposome bought to RADINT company

Purslane (PORTULACA OLERACEA) extract has the antibiotic property of wide spectrum, and has antiinflammation, can prevent and treat The skin diseases such as skin eczema, allergic dermatitis, contact dermatitis；There is good oxygen radical removing ability, illustrates that it has obviously Oxidation resistant effect；There is good skin moisture-keeping.

Dipotassium glycyrrhizinate dipotassium glycyrrhizinate is used as skin conditioning agent, predominantly the glycyrrhizin of Radix Glycyrrhizae root and stem Plain (glycyrrhizic acid) ingredient is suitble to anaphylaxis skin, anti-irritant and oil-control, moves back red and swollen antiphlogistic healing effect.Can effectively prevent skin by Sensitivity inflammation phenomenon when stimulation.Inflammation caused by counterglow has anti-inflammatory sedation, is commonly used for the makeup of Shu Min and maintenance In product.

Adenosine is a kind of trophism auxiliary agent, extensive compatibility for conditioning skin, anti-aging, it is wrinkle resistant, the facial treatment milk such as brighten； The effect of irritating hair also can inhibit the generation of dandruff；The synthesis that can interfere with viral nucleic acid is the antiviral work of Chinese medicine Property ingredient, there is antibacterial and releive effect；

Palmityl tetrapeptide -7, can by stimulating Laminin lens (LamininV) IV, VII collagen type to make skin consolidation The generation for reducing interleukins (interleukin-6), diminishes inflammation.Antisitic defect, prevention form wrinkle, relaxation and the colour of skin not ?.

Allantoin, which has, promotes cell growth, accelerates wound healing, the physiological functions such as cutin-softening albumen can help skin Skin is anti-inflammatory, releives and promotes cell repair.Allantoin can reduce the adhesion strength of corneocyte, and epidermal cell is accelerated to update.

Silantriol, hyaluronic acid, by the hyaluronic acid (150-600 thousand of three alcohol groups of methyl-monosilane and low molecular weight It Er Dun) combines and is formed.The characteristics of by silanol, small-molecular-weight hyaluronic acid, is optimised, improves its permeability and biology benefit With rate.Epidermis caused by aging can be prevented thinning, promote update of the hyaluronic acid to epidermis and cell, promote skin keratin thin Born of the same parents generate more hyaluronic acids and Portugal's ammonia polyose of candy.Prevent the formation of hyaluronic acid proinflammatory segment.This product is in addition to there is moisturizing Effect is outer, and main function is resistant to aging, promotes epidermal renewal, reaches and subtracts compact, the effect of plentiful Q bullet of wrinkling.To Exsymol The EPIDERMOSIL of company's buying.

The present invention complies fully with the indices in " cosmetics health specification " (2015 editions) of country's promulgation, the skin care item Without containing any noxious material.

Beneficial effects of the present invention: by adding niacinamide, glycine betaine, beta glucan, Radix Cynanchi Atrati extract, mulberry in formula Bark extract, overlay film saccharomycetes to make fermentation Product filtrate, Bo Nate spirulina extract, chlorella extract, rice plumule extract Object, Maltsupex, wheat malt extract, Wild soybean bud extract, sesame bud extract, seabuckthorn fruit extract, tomato fruit Extract, pomegranate berry extract, blueberry leaf extract, purslane extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, urine The compositions such as Bursin, silantriol, hyaluronic acid can play blocking, inhibit, and restore melanin, accelerate cell new old generation It thanks, accelerate melanin horn cell and fall off；Eliminate skin ageing phenomenon, inhibit, delay and reduce wrinkle generate, prevent peeling, Pore is coarse etc., and it is obscure to reduce face, promotes skin regeneration；Moisturizing provides nutritional ingredient, anti-oxidant, whitening for skin The opsonic action of skin；Skin care item of the invention are not limited by product forms, can make an addition to aqua, lotion, cream, essence Deng can be used in multiple use, compensate for the obvious shortcoming that commercial product has a single function.

Specific embodiment

The present invention is illustrated below with reference to embodiment, but the present invention is not limited to these embodiments.

The present invention is achieved through the following technical solutions: it is a kind of to block the whitening spot-removing skin care item for inhibiting reduction melanin, It is prepared by following materials by weight percentage using conventional method:

1 composition of raw materials table of table

Wherein: (water, glycerol, 1,2- hexylene glycol, 1,2- pentanediol, β-Portugal are poly- by niacinamide, glycine betaine, Radican (I) Sugar), HI-CLERA (water, butanediol, radix cynanchi atrati (CYNANCHUM ATRATUM) extract), mulberry (MORUS ALBA) bark extract Object, overlay film saccharomycetes to make fermentation Product filtrate, RA-EX Liposome (water, propylene glycol, caprylic/capric triglyceride, butanediol, Dipropylene glycol, 1,2- pentanediol, lecithin, glycerol, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, bead Algae (CHLORELLA VULGARIS) extract, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) Bud extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS- IDAEA) leaf extract), purslane (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide- 7, the weight percent of allantoin, EPIDERMOSIL (silantriol, hyaluronic acid) are as follows: 20%, 15%, 15%, 10%, 10%, 10%, 5%, 2.5%, 2.5%, 2.5%, 2.5%, 2.5%, 2.5%.

Niacinamide, glycine betaine, Radican (I) (water, glycerol, 1,2- hexylene glycol, 1,2- pentanediol, beta glucan), HI- CLERA (water, butanediol, radix cynanchi atrati (CYNANCHUM ATRATUM) extract), mulberry (MORUS ALBA) bark extract, overlay film Saccharomycetes to make fermentation Product filtrate, RA-EX Liposome are (water, propylene glycol, caprylic/capric triglyceride, butanediol, double third sweet Alcohol, 1,2- pentanediol, lecithin, glycerol, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) extract, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) bud Extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS- IDAEA) leaf extract), purslane (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide- 7, the percentage composition in (water, cream, frost) skin-protection product is added in allantoin, EPIDERMOSIL (silantriol, hyaluronic acid) are as follows: 5~30%)

Blocking of the invention inhibits the specific preparation process of whitening spot-removing skin care item of reduction melanin as follows:

(1) various raw materials in precise formula are held with vessel that are clean and disinfecting；

(2) oily phase pot, side is added in polymethyl methacrylate, PEG-60 rilanit special, octyl dodecanol polyethers -16 Stirring side is warming up to 80 DEG C~85 DEG C, is uniformly mixed it, keeps the temperature 10 minutes；

(3) by water, dipropylene glycol, glycerol, glycerin polyether -26, polyethylene glycol -32, double-PEG-18 methyl ether dimethyl-silicons Alkane, glucomannans, Sodium Hyaluronate, EDETATE SODIUM, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, Water phase pot is added in parahydroxyacet-ophenone, and warming while stirring makes it dissolve sufficiently to 85 DEG C~90 DEG C, keeps the temperature 10 minutes；

(4) water phase pot mixture is first pumped into 75~85 DEG C, then slowly takes out oily phase pot mixture by preheating emulsion pot Enter, emulsifying 15~30 minutes, keeps the temperature 20 minutes；

(5) be cooled to 45 DEG C, be added Radican (I) (water, glycerol, 1,2- hexylene glycol, 1,2- pentanediol, beta glucan), HI-CLERA (water, butanediol, radix cynanchi atrati (CYNANCHUM ATRATUM) extract), it mulberry (MORUS ALBA) bark extract, covers Film saccharomycetes to make fermentation Product filtrate, RA-EX Liposome are (water, propylene glycol, caprylic/capric triglyceride, butanediol, double third sweet Alcohol, 1,2- pentanediol, lecithin, glycerol, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) extract, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) bud Extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS- IDAEA) leaf extract), purslane (PORTULACA OLERACEA) extract, EPIDERMOSIL (silantriol, hyalomitome Acid), it is niacinamide, glycine betaine, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, tromethamine, 1,3- propylene glycol, pungent Acyl hydroximic acid, 1,2- hexylene glycol, pungent glycol, Sensiva SC50, Phenoxyethanol, essence, and be sufficiently stirred；

(6) 38 DEG C are cooled to, is discharged, is stood；

(7) after the assay was approved, filling, packaging, coding；

(8) after the assay was approved, it is put in storage.

Embodiment 1

Component in embodiment 1 is constituted by following weight percent: niacinamide: 1~6%, glycine betaine: 0.75~4.5%, Beta glucan: 0.75~4.5%, radix cynanchi atrati (CYNANCHUM ATRATUM) extract: 0.5~3%, mulberry (MORUS ALBA) is set Bark extract: 0.5~3%, overlay film saccharomycetes to make fermentation Product filtrate: 0.5~3%, Bo Nate spirulina (SPIRULINA PLATENSIS) extract: 0.0075~0.045%, chlorella (CHLORELLA VULGARIS) extract: 0.0075~ 0.045%, rice (ORYZA SATIVA) germ extracts: 0.0075~0.045%, barley (HORDEUM VULGARE) bud mentions Take object: 0.0075~0.045%, wheat (TRITICUM VULGARE) bud extract: 0.0075~0.045%, Wild soybean (GLYCINE SOJA) bud extract: 0.0075~0.045%, sesame (SESAMUM INDICUM) bud extract: 0.0075~ 0.045%, sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract: 0.0075~0.045%, tomato (SOLANUM LYCOPERSICUM) berry extract: 0.0075~0.045%, pomegranate (PUNICA GRANATUM) berry extract: 0.0075~ 0.045%, blueberry (VACCINIUM VITIS-IDAEA) leaf extract: 0.0075~0.045%, purslane (PORTULACA OLERACEA) extract: 0.125~0.75%, dipotassium glycyrrhizinate: 0.125~0.75%, adenosine: 0.125~0.75%, brown Palmitic acid acyl tetrapeptide -7:0.125~0.75%, allantoin: 0.125~0.75%, EPIDERMOSIL (silantriol, hyaluronic acid): 0.125~0.75%.

Embodiment 2

Component in embodiment 2 is constituted by following weight percent: niacinamide: 1~6%, glycine betaine: 0.75~4.5%, Beta glucan: 0.75~4.5%, radix cynanchi atrati (CYNANCHUM ATRATUM) extract: 0.5~3%, mulberry (MORUS ALBA) is set Bark extract: 0.5~3%, overlay film saccharomycetes to make fermentation Product filtrate: 0.5~3%, Bo Nate spirulina (SPIRULINA PLATENSIS) extract: 0.0075~0.045%, chlorella (CHLORELLA VULGARIS) extract: 0.0075~ 0.045%, rice (ORYZA SATIVA) germ extracts: 0.0075~0.045%, barley (HORDEUM VULGARE) bud mentions Take object: 0.0075~0.045%, wheat (TRITICUM VULGARE) bud extract: 0.0075~0.045%, Wild soybean (GLYCINE SOJA) bud extract: 0.0075~0.045%, sesame (SESAMUM INDICUM) bud extract: 0.0075~ 0.045%, sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract: 0.0075~0.045%, tomato (SOLANUM LYCOPERSICUM) berry extract: 0.0075~0.045%, pomegranate (PUNICA GRANATUM) berry extract: 0.0075~ 0.045%, blueberry (VACCINIUM VITIS-IDAEA) leaf extract: 0.0075~0.045%, purslane (PORTULACA OLERACEA) extract: 0.125~0.75%, dipotassium glycyrrhizinate: 0.125~0.75%, adenosine: 0.125~0.75%, brown Palmitic acid acyl tetrapeptide -7:0.125~0.75%, allantoin: 0.125~0.75%, EPIDERMOSIL (silantriol, hyaluronic acid): 0.125~0.75%.

Embodiment 3

Component in embodiment 3 is constituted by following weight percent: niacinamide: 1~6%, glycine betaine: 0.75~4.5%, Beta glucan: 0.75~4.5%, radix cynanchi atrati (CYNANCHUM ATRATUM) extract: 0.5~3%, mulberry (MORUS ALBA) is set Bark extract: 0.5~3%, overlay film saccharomycetes to make fermentation Product filtrate: 0.5~3%, Bo Nate spirulina (SPIRULINA PLATENSIS) extract: 0.0075~0.045%, chlorella (CHLORELLA VULGARIS) extract: 0.0075~ 0.045%, rice (ORYZA SATIVA) germ extracts: 0.0075~0.045%, barley (HORDEUM VULGARE) bud mentions Take object: 0.0075~0.045%, wheat (TRITICUM VULGARE) bud extract: 0.0075~0.045%, Wild soybean (GLYCINE SOJA) bud extract: 0.0075~0.045%, sesame (SESAMUM INDICUM) bud extract: 0.0075~ 0.045%, sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract: 0.0075~0.045%, tomato (SOLANUM LYCOPERSICUM) berry extract: 0.0075~0.045%, pomegranate (PUNICA GRANATUM) berry extract: 0.0075~ 0.045%, blueberry (VACCINIUM VITIS-IDAEA) leaf extract: 0.0075~0.045%, purslane (PORTULACA OLERACEA) extract: 0.125~0.75%, dipotassium glycyrrhizinate: 0.125~0.75%, adenosine: 0.125~0.75%, brown Palmitic acid acyl tetrapeptide -7:0.125~0.75%, allantoin: 0.125~0.75%, EPIDERMOSIL (silantriol, hyaluronic acid): 0.125~0.75%.

Table 2: each component content table of Examples 1 to 3

Technical effect

Divide the effect of the skin care item and certain commercially available brand skin care item (reference examples) of implementing 1~3 to comparison of testing, In, the skin care item of implementation 1~3 and the constituent content of certain commercially available brand skin care item are referring to table 2.

1, replenishing water and preserving moisture performance test

Female volunteers of 10 ages between 18~50 are looked for, in 20 DEG C, the indoor environment of relative humidity 50%, point The fixed area for not drawing one 2 square centimeters in forehead inhibits reduction melanin using blocking of the invention in fixed area It after whitening spot-removing skin care item and commercially available common skin care item, is tested with Corneometer CM285 skin moisture detector, synthesis takes Humidity of skin delta data, test result is as follows table:

Table 3: the replenishing water and preserving moisture performance control test table of Examples 1 to 3

From the above experimental result as can be seen, make-up water percentage of the present invention and moisturizing rate, are relatively not added with niacinamide, glycine betaine, β- Glucan, radix cynanchi atrati (CYNANCHUM ATRATUM) extract, mulberry (MORUS ALBA) bark extract, overlay film saccharomycetes to make fermentation Product filtrate, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) mention Take object, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) bud extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, Sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS-IDAEA) leaf extract, purslane It is (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, silantriol, transparent The moisturizing of the reference examples of matter acid composition and commercially available common skin care item and moistening effect are significant.

2, inhibit melanin performance test

Female volunteers of 15 ages between 18-50 years old are looked for, inhibit vat black using above block in face respectively The whitening spot-removing skin care item of pigment and commercially available common skin care item, study subject use once daily, are used continuously 30 days, test the phase Between do not use other any products.Under the conditions of 25 ± 1 DEG C of environment temperature, humidity 50 ± 5%, using MEXAMETER MX 16 Skin pigment analyzer, 1 day before using the whitening spot-removing skin care item and commercially available common skin care item that block inhibition reduction melanin After continuous use 30 days, measure the melanin content (being averaged) of its facial skin, to the white-skinned face function of the said goods into Row evaluation.Test obtained melanin inhibiting rate the result is as follows:

Table 4: the melanin rejection control test table of Examples 1 to 3

Sample	Embodiment 1	Embodiment 2	Embodiment 3	Reference examples	Commercially available common skin care item
						Melanin inhibiting rate (%)	76	65	60	3	16

From the above experimental result as can be seen, the present invention is high to melanin inhibiting rate, be relatively not added with niacinamide, glycine betaine, Beta glucan, radix cynanchi atrati (CYNANCHUM ATRATUM) extract, mulberry (MORUS ALBA) bark extract, overlay film saccharomycete hair Ferment Product filtrate, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) Extract, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) bud extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, Sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS-IDAEA) leaf extract, purslane It is (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, silantriol, transparent The whitening effect of the reference examples of matter acid composition and commercially available common skin care item is significant.

3, melanin reduction experiment

Female volunteers of 15 ages between 18-50 years old are looked for, is exposed to the sun after 3 hours under the sun, takes human cuticular tissue, It can be seen that the obvious coloration of epidermal tissue is deepened, its melanocyte is marked with fluorescent marker method, is then inhibited respectively with above block The whitening spot-removing skin care item and commercially available common skin care item for restoring melanin smear the epidermal tissue after removing, environment temperature 25 ± It 1 DEG C, under the conditions of humidity 50 ± 5%, using 16 skin pigment analyzer of MEXAMETER MX, observes melanin and reduces situation.It surveys Try obtained melanin reduction rate the result is as follows:

Table 5: the melanin reducing property control test table of Examples 1 to 3

Sample	Embodiment 1	Embodiment 2	Embodiment 3	Reference examples	Commercially available common skin care item
						Melanin inhibiting rate (%)	70	52	34	1	3

From the above experimental result as can be seen, the present invention is high to melanin reduction rate, be relatively not added with niacinamide, glycine betaine, Beta glucan, radix cynanchi atrati (CYNANCHUM ATRATUM) extract, mulberry (MORUS ALBA) bark extract, overlay film saccharomycete hair Ferment Product filtrate, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) Extract, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) bud extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, Sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS-IDAEA) leaf extract, purslane It is (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, silantriol, transparent The whitening effect of the reference examples of matter acid composition and commercially available common skin care item is significant.

4, melanin blocking experiment

Female volunteers of 15 ages between 18-50 years old are looked for, respectively with the above beauty for blocking and inhibiting to restore melanin White spot-eliminating skin care product and commercially available common skin care item smear skin of back, so that skin of back is exposed to the sun after 3 hours under the sun, in environment It 25 ± 1 DEG C of temperature, under the conditions of humidity 50 ± 5%, using 16 skin pigment analyzer of MEXAMETER MX, observes melanin and increases Add situation.Test obtained melanin blocking rate the result is as follows:

Table 5: the melanin of Examples 1 to 3 blocks performance control test table

Sample	Embodiment 1	Embodiment 2	Embodiment 3	Reference examples	Commercially available common skin care item
						Melanin blocking rate (%)	53	34	22	-20	-13

From the above experimental result as can be seen, the present invention is high to melanin blocking rate, be relatively not added with niacinamide, glycine betaine, Beta glucan, radix cynanchi atrati (CYNANCHUM ATRATUM) extract, mulberry (MORUS ALBA) bark extract, overlay film saccharomycete hair Ferment Product filtrate, Bo Nate spirulina (SPIRULINA PLATENSIS) extract, chlorella (CHLORELLA VULGARIS) Extract, rice (ORYZA SATIVA) germ extracts, barley (HORDEUM VULGARE) bud extract, wheat (TRITICUM VULGARE) bud extract, Wild soybean (GLYCINE SOJA) bud extract, sesame (SESAMUM INDICUM) bud extract, Sea-buckthorn (HIPPOPHAE RHAMNOIDES) berry extract, tomato (SOLANUM LYCOPERSICUM) berry extract, pomegranate (PUNICA GRANATUM) berry extract, blueberry (VACCINIUM VITIS-IDAEA) leaf extract, purslane It is (PORTULACA OLERACEA) extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, silantriol, transparent The whitening effect of the reference examples of matter acid composition and commercially available common skin care item is significant.

The foregoing is merely better embodiments of the invention, and the invention is not limited to above embodiment, are implementing The structural modification small there may be part in the process, if various changes or modifications of the invention are not departed from essence of the invention Mind and range, and belong within the scope of claim and equivalent technologies of the invention, then the present invention is also intended to encompass these changes And modification.

Claims (7)

1. a kind of block the whitening spot-removing skin care item for inhibiting reduction melanin, which is characterized in that including having blocking, suppression below The whitening spot-removing prescription that system, reduction melanin act on: niacinamide, glycine betaine, beta glucan, Radix Cynanchi Atrati extract, paper mulberry bark are extracted Object, overlay film saccharomycetes to make fermentation Product filtrate, Bo Nate spirulina extract, chlorella extract, rice germ extracts, fructus hordei germinatus Extract, wheat malt extract, Wild soybean bud extract, sesame bud extract, seabuckthorn fruit extract, tomato berry extract, stone Pomegranate berry extract, blueberry leaf extract, purslane extract, dipotassium glycyrrhizinate, adenosine, palmityl tetrapeptide -7, allantoin, silane Triol, hyaluronic acid.

2. according to claim 1 block the whitening spot-removing skin care item for inhibiting reduction melanin, which is characterized in that the tool There is the whitening spot-removing component of blocking, inhibition, reduction melanin effect blocking the whitening spot-removing skin care item for inhibiting reduction melanin In weight percent are as follows: niacinamide 1~6%, glycine betaine 0.75~4.5%, beta glucan 0.75~4.5%, radix cynanchi atrati extract Object 0.5~3%, Cortex Mori extract 0.5~3%, overlay film saccharomycetes to make fermentation Product filtrate 0.5~3%, Bo Nate spirulina mention Take object 0.0075~0.045%, chlorella extract 0.0075~0.045%, rice germ extracts 0.0075~0.045%, Maltsupex 0.0075~0.045%, wheat malt extract 0.0075~0.045%, Wild soybean bud extract 0.0075 ~0.045%, sesame bud extract 0.0075~0.045%, seabuckthorn fruit extract 0.0075~0.045%, tomato fruit are extracted Object 0.0075~0.045%, pomegranate berry extract 0.0075~0.045%, blueberry leaf extract 0.0075~0.045%, horse Sativa extract 0.125~0.75%, dipotassium glycyrrhizinate 0.125~0.75%, adenosine 0.125~0.75%, palmityl tetrapeptide- 7 0.125~0.75%, allantoin 0.125~0.75%, EPIDERMOSIL0.125~0.75%.

3. according to claim 2 block the whitening spot-removing skin care item for inhibiting reduction melanin, which is characterized in that the tool There is the whitening spot-removing component of blocking, inhibition, reduction melanin effect blocking the whitening spot-removing skin care item for inhibiting reduction melanin In by weight percentage are as follows: niacinamide 4%, glycine betaine 3%, beta glucan 0.03%, Radix Cynanchi Atrati extract 0.1%, paper mulberry bark mention Take object 2%, overlay film saccharomycetes to make fermentation Product filtrate 2%, Bo Nate spirulina extract 0.03%, chlorella extract 0.03%, rice germ extracts 0.03%, Maltsupex 0.03%, wheat malt extract 0.03%, Wild soybean bud extract Object 0.03%, sesame bud extract 0.03%, seabuckthorn fruit extract 0.03%, tomato berry extract 0.03%, pomegranate fruit are extracted Object 0.03%, blueberry leaf extract 0.03%, purslane extract 0.5%, dipotassium glycyrrhizinate 0.5%, adenosine 0.5%, palm Acyl tetrapeptide -7 0.5%, allantoin 0.5%, EPIDERMOSIL0.5%.

4. moisturizing according to claim 2, whitening, the skin care item releived, which is characterized in that it is described have block, inhibit, Restore the whitening spot-removing component of the melanin effect percentage by weight in blocking the whitening spot-removing skin care item for inhibiting reduction melanin Than are as follows: niacinamide 3%, glycine betaine 2.25%, beta glucan 0.0225%, Radix Cynanchi Atrati extract 0.075%, Cortex Mori extract 1.5%, overlay film saccharomycetes to make fermentation Product filtrate 1.5%, Bo Nate spirulina extract 0.0225%, chlorella extract 0.0225%, rice germ extracts 0.0225%, Maltsupex 0.0225%, wheat malt extract 0.0225%, open country are big Bean sprouts extract 0.0225%, sesame bud extract 0.0225%, seabuckthorn fruit extract 0.0225%, tomato berry extract 0.0225%, pomegranate berry extract 0.0225%, blueberry leaf extract 0.0225%, purslane extract 0.375%, glycyrrhizic acid Dipotassium 0.375%, adenosine 0.375%, palmityl tetrapeptide -7 0.375%, allantoin 0.375%, EPIDERMOSIL0.375%.

5. according to claim 2 block the whitening spot-removing skin care item for inhibiting reduction melanin, which is characterized in that the tool There is the whitening spot-removing component of blocking, inhibition, reduction melanin effect blocking the whitening spot-removing skin care item for inhibiting reduction melanin In by weight percentage are as follows: niacinamide 2%, glycine betaine 1.5%, beta glucan 0.015%, Radix Cynanchi Atrati extract 0.05%, mulberry tree Bark extract 1%, overlay film saccharomycetes to make fermentation Product filtrate 1%, Bo Nate spirulina extract 0.015%, chlorella extract 0.015%, rice germ extracts 0.015%, Maltsupex 0.015%, wheat malt extract 0.015%, Wild soybean bud Extract 0.015%, sesame bud extract 0.015%, seabuckthorn fruit extract 0.015%, tomato berry extract 0.015%, stone Pomegranate berry extract 0.015%, blueberry leaf extract 0.015%, purslane extract 0.25%, dipotassium glycyrrhizinate 0.25%, gland Glycosides 0.25%, palmityl tetrapeptide -7 0.25%, allantoin 0.25%, EPIDERMOSIL0.25%.

6. the blocking according to any one of claim 2-5 inhibits the whitening spot-removing skin care item of reduction melanin, feature It is, includes silantriol and hyaluronic acid in the EPIDERMOSIL, the silantriol and hyaluronic acid ratio be 90~ 99:1~10.

7. a kind of preparation side for the whitening spot-removing skin care item as claimed in claims 1-5 for blocking inhibition reduction melanin Method, which comprises the steps of:

(1) various raw materials in precise formula are held with vessel that are clean and disinfecting；

(2) oily phase pot, side stirring is added in polymethyl methacrylate, PEG-60 rilanit special, octyl dodecanol polyethers -16 While being warming up to 80 DEG C~85 DEG C, it is uniformly mixed it, keeps the temperature 10 minutes；

(3) by water, dipropylene glycol, glycerol, glycerin polyether -26, polyethylene glycol -32, double-PEG-18 methyl ether dimethylsilanes, Glucomannans, Sodium Hyaluronate, EDETATE SODIUM, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, to hydroxyl Water phase pot is added in benzoylformaldoxime, and warming while stirring makes it dissolve sufficiently to 85 DEG C~90 DEG C, keeps the temperature 10 minutes；

(4) water phase pot mixture is first pumped into 75~85 DEG C, is then slowly pumped into oily phase pot mixture by preheating emulsion pot, Emulsifying 15~30 minutes, keep the temperature 20 minutes；

(5) 45 DEG C are cooled to, water, glycerol, 1,2- hexylene glycol, 1,2- pentanediol, beta glucan, butanediol, radix cynanchi atrati is added and extracts It is object, Cortex Mori extract, overlay film saccharomycetes to make fermentation Product filtrate, propylene glycol, caprylic/capric triglyceride, butanediol, double third sweet Alcohol, 1,2- pentanediol, lecithin, glycerol, Bo Nate spirulina extract, chlorella extract, rice germ extracts, fructus hordei germinatus Extract, wheat malt extract, Wild soybean bud extract, sesame bud extract, seabuckthorn fruit extract, tomato berry extract, stone Pomegranate berry extract, blueberry leaf extract, purslane extract, EPIDERMOSIL, niacinamide, glycine betaine, dipotassium glycyrrhizinate, gland Glycosides, palmityl tetrapeptide -7, allantoin, tromethamine, 1,3- propylene glycol, decoyl hydroximic acid, 1,2- hexylene glycol, pungent glycol, ethyl Hexyl glycerol, Phenoxyethanol, essence, and be sufficiently stirred；

(6) 38 DEG C are cooled to, is discharged, is stood；

(7) after the assay was approved, filling, packaging, coding, storage are stand-by.