CN110179735A - Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care - Google Patents
Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care Download PDFInfo
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- CN110179735A CN110179735A CN201910618821.4A CN201910618821A CN110179735A CN 110179735 A CN110179735 A CN 110179735A CN 201910618821 A CN201910618821 A CN 201910618821A CN 110179735 A CN110179735 A CN 110179735A
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- raw material
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- dispelling
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care the invention discloses a kind of.By weight, it is described have effects that Vitamin K, the plant composition for eye pouch of dispelling is composed of the following components: 5~50 parts of Honegsukle flower P.E, 5~90 parts of gadol extract, 1~20 part of 5~50 parts of Saussurea involucrata extract and carnosine and saccharomycete/10~90 parts of rice fermentation liquid.Plant prescription provided by the invention is obscure to blee, pigmentation improves significantly；Have and removes free radical, cell viability that is anti-oxidant, improving horn cell, the effect of repairing skin tissue；Wrinkle caused by the atrophy of skin of face organizational slack can be improved, there is a degree of expeling effect to eye pouch.Plant prescription provided by the invention is process by natural plant raw material, be can be used for eye haustra -dsipelling and is repaired in the external use skin care of skin lightening.
Description
Technical field
The present invention relates to plant society field of pharmaceutical chemistry technology, have Vitamin K, eye of dispelling more particularly, to one kind
The plant composition of bag effect and its application in external use skin care.
Background technique
With the improvement of living standards, being promoted to the pursuit of beauty, especially women, people are more next to face skin nursing
More pay attention to.Whitening product, because its can bright color, improve that skin is obscure, nti-freckle, be always the very favorite skin care of Nails
Product mainstream, the market space are huge.
The genesis mechanism of eye pouch is more complicated.With advancing age, eye part skin muscle relaxes gradually, and orbital fat moves
Position prolapsus.In addition, eye socket bone reduces, it can also allow lipochondrion more prominent, eye pouch is the preferential performance of human face's aging.Eye pouch
Generation it is also closely bound up with life style, if staying up late, having not enough sleep for a long time, ceaselessly people is also easier to grow eye tobacco and wine
Bag.How effectively to drive away eye pouch is also the hot spot that modern female is extremely paid close attention to.
Functional cosmetics also have certain given efficacy, are pushed away while meeting daily beautify product demand
It is high.The usage history that Chinese medicine has more than 2,000 years in China, also has more accumulation, safely and effectively in terms of skin care.How sufficiently
The mechanism of action of Chinese medicine multicomponent multipath multiple target point is played, developing, there are the skin care item of composite efficacy to be one practical meaning very much
The research topic of justice.
Therefore, how to develop it is a kind of can effectively eye haustra -dsipelling repair skin lightening natural skin care product, can be to avoid operation
Hidden danger reaches healing purpose, and before capable of should also being had bigger application by the popular welcome of consumer, this kind of cosmetics
Scape is current art technical staff technical problem urgently to be solved.
Summary of the invention
Of the existing technology in order to solve the problems, such as, the object of the present invention is to provide one kind to have Vitamin K, eye of dispelling
The plant composition of bag effect is the characteristics of giving full play to the advantage of natural plants, play multicomponent, multipath, multiple target point
Pure plant raw material, can be used for Vitamin K, eye pouch effect of dispelling a variety of external use skin cares in.
The present invention also provides the above-mentioned plant compositions with Vitamin K, eye pouch of dispelling in external use skin care
Application.
To achieve the goals above, the following technical solution is employed by the present invention:
It is a kind of to have effects that Vitamin K is dispelled the plant prescription of eye pouch, is grouped as by the group of following parts by weight:
5~50 parts of Honegsukle flower P.E, 5~90 parts of gadol extract, 5~50 parts of Saussurea involucrata extract and carnosine 1~20
Part and saccharomycete/10~90 parts of rice fermentation liquid.
Preferably, a kind of plant composition with Vitamin K, eye pouch of dispelling, is by the group of following parts by weight
It is grouped as:
10~25 parts of Honegsukle flower P.E, 10~50 parts of gadol extract, 10~25 parts of Saussurea involucrata extract and carnosine 5~
15 parts and saccharomycete/20~60 parts of rice fermentation liquid.
Preferably, the Honegsukle flower P.E is that honeysuckle is extracted with water, and after filtering out the dregs of a decoction, concentration；By concentrate
Drying forms after filtering；Or it is formed with drying after macroporous resin enrichment；
The gadol extract is that root of kirilow rhodiola is extracted with water, after filtering out the dregs of a decoction, concentration；It is dry after concentrate is filtered
It forms；Or it is formed with drying after macroporous resin enrichment；
The Saussurea involucrata extract is that saussurea involucrata is extracted with water, after filtering out the dregs of a decoction, concentration；After concentrate is filtered it is dry and
At；Or it is formed with drying after macroporous resin enrichment.
Preferably, on the basis of single extract gross mass, the content of the Honegsukle flower P.E Content of Chlorogenic Acid is 5~
80wt%；The content of rhodioside is 5~80wt% in the gadol extract；Organic acid contains in the Saussurea involucrata extract
Amount is 5~80wt%；The purity of the carnosine is 90-100%；Polyoses content 5 in the saccharomycete/rice fermentation liquid~
40wt%.
Furthermore, a kind of to have effects that Vitamin K is dispelled the plant composition of eye pouch, it is by technique below
Step is made:
1) it is weighed respectively according to following weight:
5~50 parts of Honegsukle flower P.E, 5~90 parts of gadol extract, 5~50 parts of Saussurea involucrata extract and carnosine 1~20
Part and saccharomycete/10~90 parts of rice fermentation liquid；
2) raw material in step 1) is merged, add heating after 10~100 parts of water and 5~60 parts of dihydric alcohol, ultrasound or
Stirring, makes sufficiently to dissolve；
3) extracting solution for obtaining step 2) is filtered or is centrifuged, and obtains corresponding extracting solution；
4) preservative is added in the extracting solution that step 3) obtains, stirs evenly to get with Vitamin K, eye pouch of dispelling
The plant composition of effect.
In addition, the present invention also provides a kind of above-mentioned plant compositions with Vitamin K, eye pouch of dispelling in external application
Application in skin care item, by have effects that Vitamin K dispel eye pouch external use skin care gross mass on the basis of, external application shield
Plant composition in skin product containing 0.5~10wt% and 90%~95.5% external use skin care field customary adjuvant.
Preferably, the external use skin care is face cream, facial mask, Essence, lotion or aqua.
According to using approach different, plant composition provided by the invention as external-use skin care product made of raw material, and
It is not limited to lotion, can also be fabricated to face cream, facial mask, Essence etc..Can also be according to known method in skin care industry field, it will
A variety of different external-use skin care products are made in above-mentioned plant prescription.
A kind of lotion with Vitamin K, eye pouch of dispelling, to have effects that Vitamin K is dispelled the lotion of eye pouch
On the basis of gross mass, the lotion is made of the raw material of following mass percentage:
A phase raw material: EDTA-2Na 0.1~0.3%, carbomer 0.2~1%, glycerol 1~5%, panthenol 0.1~1%, sea
Algae sugar 1~2%, 1,3-BDO 2~4% have effects that Vitamin K is dispelled the plant prescription 1~8% of eye pouch, water 60~
80%；
B phase raw material: PEG-100 stearate 1~3%, cetostearyl alcohol 0.5~1.5%, tristerin 0.5~
1%, polyisobutene 2~7%, caprylic capric glyceryl ester 1~5%, Butyrospermum parkii 0.5~3%, isohexadecane 2~7%；
C phase raw material: 10%NaOH 0.4~2.5%, preservative 0.1~0.2%.
Preferably, it is described have effects that Vitamin K dispel eye pouch lotion in containing 5-8wt% have desalinate it is black
Eyelet is dispelled the plant prescription of eye pouch effect.
The preparation method of the above-mentioned lotion with Vitamin K, eye pouch of dispelling, comprising the following steps:
1) it adds water in kettle, carbomer is added, impregnate 10min, heating stirring is to raw material at a temperature of 80~85 DEG C
All dissolution is complete；
2) A phase raw material is continuously added, keeping the temperature 80~85 DEG C of stirrings, all dissolution is complete to raw material, after heat preservation 10min sterilizing
A phase feedstock processing object is obtained, is kept the temperature spare；
3) B phase raw material is added in oily phase pot, 80~85 DEG C of agitating and heating dissolutions completely, are kept the temperature spare；
4) A phase feedstock processing object obtained in step 2) is pumped into emulsion pot, is pumped into B phase raw material under homogeneous stirring
In emulsion pot, start to cool down after homogeneous 5min, stirring heat preservation 10min；
5) when temperature drops to 40~45 DEG C, C phase raw material is added in emulsion pot, discharges after mixing evenly, obtains tool
There is Vitamin K to dispel the lotion of eye pouch effect.
By above-mentioned technical proposal, the invention has the following beneficial effects:
1) plant composition provided by the invention has stronger removing free radical, oxidation resistant ability, adjusts fatty generation
It thanks, inhibits pigmentation, improve the cell viability of horn cell, the effect of repairing skin tissue；Skin of face tissue can be improved
Wrinkle caused by relaxation atrophy has a degree of expeling effect to eye pouch；
2) plant composition provided by the invention is pure plant raw material, according to using approach different, can be used for adding
Into a variety of cosmetics, skin care item and other external-use skin care products, however it is not limited to which lotion or aqua can also be fabricated to face cream, face
Film, Essence etc.；A variety of different external applications can be made in above-mentioned plant prescription according to known method in skin care industry field
Product, application range and its wide；
3) by the experience of many years clinical use, it has been found that the prescription is obscure to blee, pigmentation have it is bright
Aobvious improvement result；Also have and removes free radical, cell viability that is anti-oxidant, improving horn cell, the work of repairing skin tissue
With；The expeling effect of face skin wrinkle and eye pouch can also be improved.
Detailed description of the invention
Fig. 1 is that the present invention has effects that the plant composition of Vitamin K, eye pouch of dispelling to the antioxidation of ABTS
Power curve figure.
Fig. 2 is that the present invention has effects that the plant composition of Vitamin K, eye pouch of dispelling to the antioxidation of ABTS
Efficacy assessments figure.
Specific embodiment
Below by specific preferred embodiment combination attached drawing, the technical solutions of the present invention will be further described.
In the present invention, if not refering in particular to, all devices and raw material is commercially available or the industry is common are following
Method in embodiment is unless otherwise instructed the common process method of this field.
A kind of plant composition with Vitamin K, eye pouch of dispelling is grouped as by the group of following parts by weight:
5~50 parts of Honegsukle flower P.E, 5~90 parts of gadol extract, 5~50 parts of Saussurea involucrata extract and carnosine 1~20
Part and saccharomycete/10~90 parts of rice fermentation liquid.
The present invention selects honeysuckle, root of kirilow rhodiola and three taste plant of saussurea involucrata to retain original function using modern extraction and separation technology
Ingredient is imitated, three Plant Extracts with Vitamin K, eye pouch of dispelling are made；Compound addition carnosine and saccharomycete/big
Rice fermentation liquid is made the composition, while providing the cosmetic product containing the plant composition.
The pharmacological effect of each component is as follows:
1) honeysuckle is bitter in taste for Caprifoliaceae woodbine honeysuckle and congener dry flower or with the flower just opened
It is cold, there is the effect of heat-clearing and damp-drying drug, desinsection, diuresis.Honeysuckle is just extensive and famous with its medical value since ancient times, and the modern times grind
Study carefully and show that it has the effects that antibacterial anti-inflammatory, antipyretic, reducing blood lipid adjust fat metabolism, reinforce functioning immune, additionally have compared with
The ability of strong oxidation and removing free radicals.
2) root of kirilow rhodiola is the root and rhizome of Rhodida plant root of kirilow rhodiola, originates from Tibet, northwestern Yunnan Province, western Sichuan etc.
Himalaya highlands.Nature and flavor sweetness and bitterness is flat, be mainly used for improving sleep, blood-enriching and blood-promoting circulation, anti-cerebral anoxia, it is antifatigue, invigorate blood circulation and stop
Blood, remove blood stasis and detumescence, antipyretic bring down a fever, nourishes vigour and other effects at clearing lung and relieving cough.Effect is mainly anti anoxia, antifatigue, antibacterial, resists
Radiation delays senescence, removes free radical, inhibits lipid peroxide generation and the dual regulation to endocrine system.
3) lanatechead saussurea herb with flower, Uighur is entitled " Ta Gelailisi ", is composite family herbaceos perennial, is world-famous
Rare plant.Main active includes: flavonoids, saussurea involucrata lactones, organic acid, volatile oil, polysaccharide etc..Saussurea involucrata extract can be deep
Enter skin histology, Cell membrane lipids peroxidating, delaying skin aging can be prevented significantly to the generation of free radical resisting.In addition,
Saussurea involucrata extract also has the function of anti-inflammatory, analgesia and detumescence.Lanatechead saussurea herb with flower contains protein, amino acid, flavone compound, life
Alkaloids etc. have clearing and activating the channels and collaterals, dispelling cold and removing dampness, hemostasia and detumescence, isostere endotoxin and other effects.
4) carnosine is a kind of active peptide of multifunctional antisenescence, has stronger oxidation resistance, stimulation collagen
Synthesis inhibits MMP-1 effect.
5) rice is after the fermentation of natural S. cervisiae, rich in a variety of active ingredients needed for skin for example oligosaccharide, organic acid,
Polypeptide, amino acid etc. have a variety of function such as moisturizing, whitening and anti-aging also containing to the vital ceramide ingredient of skin
Effect.
Plant composition provided by the invention is pure plant raw material, can be used for Vitamin K, eye pouch effect of dispelling
A variety of external-use skin care products in.
A kind of external use skin care with Vitamin K, eye pouch of dispelling, to have effects that Vitamin K is dispelled eye pouch
External use skin care gross mass on the basis of, containing 0.5~10wt% there is Vitamin K to dispel eye in the external use skin care
The plant composition of bag effect.
Plant group object provided by the invention, the skin problem such as, pigmentation obscure to blee tool improve significantly
Effect；Also have and removes free radical, cell viability that is anti-oxidant, improving horn cell, the effect of repairing skin tissue；It can improve
Wrinkle caused by the atrophy of skin of face organizational slack has a degree of expeling effect to eye pouch.
Plant composition provided by the invention is process by natural plant raw material, and it is bright to can be used for eye haustra -dsipelling reparation
In the external-use skin care product of skin.
The unit of following parts by weight is g or kg.
Embodiment 1
A kind of plant composition with Vitamin K, eye pouch of dispelling is made by following processing step:
1) it is weighed respectively according to following weight:
5 parts of Honegsukle flower P.E, 5 parts of gadol extract, 1 part of 5 parts of Saussurea involucrata extract and carnosine and saccharomycete/rice are sent out
10 parts of zymotic fluid；The preparation process of the Honegsukle flower P.E, gadol extract and Saussurea involucrata extract is: respectively by honeysuckle,
Root of kirilow rhodiola, saussurea involucrata add 20 parts of water to extract, after filtering out the dregs of a decoction, concentration；Drying forms after concentrate is filtered；Or use macroreticular resin
Drying forms after enrichment；
2) raw material in step 1) is merged, adds heating, ultrasound or stirring after 10 parts of water and 5 parts of dihydric alcohol, makes to fill
Divide dissolution；
3) extracting solution for obtaining step 2) is filtered or is centrifuged, and obtains corresponding extracting solution；
4) preservative is added in the extracting solution that step 3) obtains, stirs evenly and dispels eye pouch to get with Vitamin K
The plant composition of effect.
Wherein, on the basis of single extract gross mass, the content of the Honegsukle flower P.E Content of Chlorogenic Acid is 20wt%,
The content of rhodioside is 30wt% in the gadol extract, and the content of organic acid is in the Saussurea involucrata extract
30wt%, the carnosine purity is 99%, polyoses content 20wt% in saccharomycete/rice fermentation liquid.
Embodiment 2
A kind of plant composition with Vitamin K, eye pouch of dispelling is made by following processing step:
1) it is weighed respectively according to following weight:
10 parts of Honegsukle flower P.E, 10 parts of gadol extract, 50 parts of 10 parts of Saussurea involucrata extract and carnosine and saccharomycete/big
30 parts of fermentation liquid of rice；The preparation process of the Honegsukle flower P.E, gadol extract and Saussurea involucrata extract is: respectively by gold and silver
Flower, root of kirilow rhodiola, saussurea involucrata add 40 parts of water to extract, after filtering out the dregs of a decoction, concentration；Drying forms after concentrate is filtered；Or use macropore
Drying forms after resin concentration；
2) raw material in step 1) is merged, adds heating, ultrasound or stirring after 20 parts of water and 10 parts of dihydric alcohol, makes to fill
Divide dissolution；
3) extracting solution for obtaining step 2) is filtered or is centrifuged, and obtains corresponding extracting solution；
4) preservative is added in the extracting solution that step 3) obtains, stirs evenly and dispels eye pouch to get with Vitamin K
The plant prescription of effect.
Wherein, on the basis of single extract gross mass, the content of the Honegsukle flower P.E Content of Chlorogenic Acid is 40wt%,
The content of rhodioside is 40wt% in the gadol extract, and the content of organic acid is in the Saussurea involucrata extract
20wt%, the carnosine purity is 98%, polyoses content 25wt% in saccharomycete/rice fermentation liquid.
Embodiment 3
A kind of plant composition with Vitamin K, eye pouch of dispelling is made by following processing step:
1) weigh respectively according to following weight: 15 parts of Honegsukle flower P.E, 5 parts of gadol extract, saussurea involucrata mentions
Take 10 parts of 5 parts of object and carnosine and saccharomycete/40 parts of rice fermentation liquid；The Honegsukle flower P.E, gadol extract and saussurea involucrata
The preparation process of extract is: add 30 parts of water to extract honeysuckle, root of kirilow rhodiola, saussurea involucrata respectively, after filtering out the dregs of a decoction, and concentration；It will
Drying forms after concentrate filtering；Or it is formed with drying after macroporous resin enrichment；
2) raw material in step 1) is merged, adds heating, ultrasound or stirring after 30 parts of water and 15 parts of dihydric alcohol, makes to fill
Divide dissolution；
3) extracting solution for obtaining step 2) is filtered or is centrifuged, and obtains corresponding extracting solution；
4) preservative is added in the extracting solution that step 3) obtains, stirs evenly and dispels eye pouch to get with Vitamin K
The plant composition of effect.
Wherein, on the basis of single extract gross mass, the content of the Honegsukle flower P.E Content of Chlorogenic Acid is 50wt%,
The content of rhodioside is 50wt% in the gadol extract, and the content of organic acid is in the Saussurea involucrata extract
30wt%, the carnosine purity is 99%, polyoses content 20wt% in saccharomycete/rice fermentation liquid.
Embodiment 4 (have effects that Vitamin K dispel the lotion of eye pouch)
A kind of preparation method of the lotion with Vitamin K, eye pouch of dispelling, comprising the following steps:
1) it adds water in kettle, carbomer is added, impregnate 10min, heating stirring is whole to raw material at a temperature of 80 DEG C
Dissolution is complete；
2) A phase raw material is continuously added, keeping the temperature 80 DEG C of stirrings, all dissolution completely, obtains A after heat preservation 10min sterilizing to raw material
Phase feedstock processing object is kept the temperature spare；
A phase raw material: EDTA-2Na 0.1%, carbomer 0.2%, glycerol 1%, panthenol 0.1%, trehalose 1%, 1,3- fourth
Glycol 2%, the plant composition 5% of embodiment 1, surplus is water；
3) B phase raw material is added in oily phase pot, 80~85 DEG C of agitating and heating dissolutions completely, are kept the temperature spare；
B phase raw material: PEG-100 stearate 1%, cetostearyl alcohol 0.5%, tristerin 0.5%, polyisobutene
2%, caprylic capric glyceryl ester 1%, Butyrospermum parkii 0.5%, isohexadecane 2%；
4) A phase feedstock processing object obtained in step 2) is pumped into emulsion pot, is pumped into B phase raw material under homogeneous stirring
In emulsion pot, start to cool down after homogeneous 5min, stirring heat preservation 10min；
5) when temperature drops to 40 DEG C, C phase raw material is added in emulsion pot, discharges after mixing evenly；
C phase raw material: 10%NaOH 0.4%, preservative 0.1% obtain lotion.
Embodiment 5 (have effects that Vitamin K dispel the lotion of eye pouch)
A kind of preparation method of the lotion with Vitamin K, eye pouch of dispelling, comprising the following steps:
1) it adds water in kettle, carbomer is added, impregnate 10min, heating stirring is whole to raw material at a temperature of 85 DEG C
Dissolution is complete；
2) A phase raw material is continuously added, keeping the temperature 85 DEG C of stirrings, all dissolution completely, obtains A after heat preservation 10min sterilizing to raw material
Phase feedstock processing object is kept the temperature spare；
A phase raw material: EDTA-2Na 0.3%, carbomer 1%, glycerol 5%, panthenol 1%, trehalose 2%, 1,3-BDO
4%, the plant composition 5% of embodiment 2, surplus is water；
3) B phase raw material is added in oily phase pot, 85 DEG C of agitating and heating dissolutions completely, are kept the temperature spare；
B phase raw material: PEG-100 stearate 3%, cetostearyl alcohol 1.5%, tristerin 1%, polyisobutene
7%, caprylic capric glyceryl ester 5%, Butyrospermum parkii 3%, isohexadecane 7%；
4) A phase feedstock processing object obtained in step 2) is pumped into emulsion pot, is pumped into B phase raw material under homogeneous stirring
In emulsion pot, start to cool down after homogeneous 5min, stirring heat preservation 10min；
5) when temperature drops to 45 DEG C, C phase raw material is added in emulsion pot, discharges after mixing evenly；
C phase raw material: 10%NaOH 2.5%, preservative 0.2% obtain lotion.
Embodiment 6 (lotion with Vitamin K, eye pouch of dispelling)
A kind of preparation method of the lotion with Vitamin K, eye pouch of dispelling, comprising the following steps:
1) it adds water in kettle, carbomer is added, impregnate 10min, heating stirring is whole to raw material at a temperature of 83 DEG C
Dissolution is complete；
2) A phase raw material is continuously added, keeping the temperature 82 DEG C of stirrings, all dissolution completely, obtains A after heat preservation 10min sterilizing to raw material
Phase feedstock processing object is kept the temperature spare；
A phase raw material: EDTA-2Na 0.2%, carbomer 0.6%, glycerol 3%, panthenol 0.8%, trehalose 1.5%, 1,3-
Butanediol 3%, the plant composition 5% of embodiment 3, surplus is water；
3) B phase raw material is added in oily phase pot, 82 DEG C of agitating and heating dissolutions completely, are kept the temperature spare；
B phase raw material: PEG-100 stearate 2%, cetostearyl alcohol 1%, tristerin 0.8%, polyisobutene
5%, caprylic capric glyceryl ester 3%, Butyrospermum parkii 2%, different ten six 5%；
4) A phase feedstock processing object obtained in step 2) is pumped into emulsion pot, is pumped into B phase raw material under homogeneous stirring
In emulsion pot, start to cool down after homogeneous 5min, stirring heat preservation 10min；
5) when temperature drops to 42 DEG C, C phase raw material is added in emulsion pot, discharges after mixing evenly；
C phase raw material: 10%NaOH 2%, preservative 0.15% obtain lotion.
Embodiment 7 (have effects that Vitamin K dispel the Essence of eye pouch)
It is a kind of have effects that Vitamin K, eye pouch of dispelling Essence preparation method, comprising the following steps:
1) it adds water in kettle, is heated to 80~85 DEG C；
2) other raw materials of A phase are added, keeps the temperature 80~85 DEG C of stirrings and is all dissolved to raw material completely, after heat preservation 10min sterilizing
Cool to 40~45 DEG C；
3) B phase raw material is added in kettle, stirring and dissolving is complete；
4) C phase raw material is added in kettle, stirs evenly discharging, obtains Essence.
Wherein:
A phase raw material: EDTA- disodium 0.01~0.3%, xanthan gum 0.02~1%, butanediol 1~5%, panthenol 0.1~
1%, 0.1~2%, 1,2- pentanediol 0.2~4% of parahydroxyacet-ophenone, water 60~90%；
B phase raw material: biological carbohydrate gum 11~5%, the plant composition 1~8% of embodiment 1；
C phase raw material: Cremophor RH40 0.1~2.5%, (daily) essence 0.01~0.2%.
Effete test embodiment
1, the anti-oxidant experiment of ABTS
Have effects that the dispel plant composition of eye pouch of Vitamin K is adopted by the anti-oxidant experiment of ABTS to of the invention
With half-inhibitory concentration IC50Method examine its antioxidation.
Experimental principle:
ABTS is oxidized to the ABTS of green under oxidant appropriate effect+, ABTS in the presence of antioxidant+?
Generation can be suppressed, and measure ABTS in 405nm+Absorbance can measure and calculate the total antioxidant capacity of sample.
Experimental method: for trying object+ABTS+Room temperature is protected from light 10min.
The plant composition can effectively inhibit the oxidation of ABTS, IC to experimental result as shown in Figure 1:50For 1.43ug/mL.
2, the Scavenging activity of free radical is tested
Have effects that Vitamin K is dispelled the plant composition of eye pouch, and ABTS is passed through to of the invention+Radicals scavenging
Experiment, calculates to free radical scavenging activity.
Experimental principle:
ABTS+The a length of 734nm of the maximum absorption wave of radical ion, so, can with the maximum absorbance A at this come
Detect ABTS+The concentration of radical ion.If the absorbance that 734nm goes out reduces, so that it may show ABTS+Free radical from
Son is removed.
Experimental procedure:
25mL ABTS stock solution and 25mL K are taken respectively2S2O8Stock solution, room temperature is protected from light 12- after the two uniformly mixes
16h obtains ABTS working solution.ABTS working solution 2mL made from previous step is taken uniformly to mix with plant composition 1mL, room temperature is kept away
Light measures its absorbance A after placing half an hour at 734nm1；Parallel test takes 2mL ethyl alcohol uniformly to mix with plant composition 1mL
It closes, room temperature measures its absorbance A after avoid light place half an hour at 734nm0。
Clearance rate calculation formula are as follows: free radical scavenging activity (%)=[(A0-A1)/A0] × 100%；
As shown in Fig. 2, having effects that the plant composition of Vitamin K, eye pouch of dispelling to the anti-oxidant of ABTS for the present invention
The effect of effect evaluation figure.By in Fig. 2 it can be seen that absorbance A1It is 0.756, absorbance A2It is 0.219, passes through clearance rate meter
Calculating formula and can calculating free radical scavenging activity is 71.02%, and it is apparent to illustrate that the plant composition has ABTS free radical
Scavenging effect.
3, Vitamin K is tested
120 more serious volunteers of black eye are chosen, every group 20 are divided into six groups, respectively using embodiment 4, implementation
The proportion of example 5 and embodiment 6 is prepared using above-mentioned preparation method, and comparative example 4,5,6 is respectively by being added without plant society
The thing 4,5,6 of object is prepared, and volunteers obtain 1 experimental result of table using after product 28 days.1 comparative example 4-6 of table and implementation
The Vitamin K test of example 4-6
Known to 1 experimental result of table: embodiment 4, embodiment 5, embodiment 6 respectively with comparative example 4, comparative example 5, comparative example 6
Compared to the effect for having apparent Vitamin K, illustrate that the plant composition has the effect of apparent Vitamin K.
The above described is only a preferred embodiment of the present invention, be not intended to limit the present invention in any form, therefore
Without departing from the technical solutions of the present invention, to the above embodiments according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (10)
1. a kind of plant composition with Vitamin K, eye pouch of dispelling, which is characterized in that by weight percentage, institute
Plant composition is stated to be made of following material component:
5~50 parts of Honegsukle flower P.E, 5~90 parts of gadol extract, 1~20 part of 5~50 parts of Saussurea involucrata extract and carnosine and
Saccharomycete/10~90 parts of rice fermentation liquid.
2. having effects that the plant composition of Vitamin K, eye pouch of dispelling as described in claim 1, which is characterized in that by weight
Percentages are measured, the plant composition is made of following material component:
10~25 parts of Honegsukle flower P.E, 10~50 parts of gadol extract, 10~25 parts and 5~15 parts of carnosine of Saussurea involucrata extract
With saccharomycete/20~60 parts of rice fermentation liquid.
3. having effects that the plant composition of Vitamin K, eye pouch of dispelling as claimed in claim 1 or 2, it is characterised in that:
The Honegsukle flower P.E is that honeysuckle is extracted with water, after filtering out the dregs of a decoction, concentration；After concentrate is filtered it is dry and
At；Or it is formed with drying after macroporous resin enrichment；
The gadol extract is that root of kirilow rhodiola is extracted with water, after filtering out the dregs of a decoction, concentration；After concentrate is filtered it is dry and
At；Or it is formed with drying after macroporous resin enrichment；
The Saussurea involucrata extract is that saussurea involucrata is extracted with water, after filtering out the dregs of a decoction, concentration；Drying forms after concentrate is filtered；Or
It is formed with drying after macroporous resin enrichment.
4. having effects that the plant composition of Vitamin K, eye pouch of dispelling as claimed in claim 3, it is characterised in that:
On the basis of the gross mass of single extract, the content of the Honegsukle flower P.E Content of Chlorogenic Acid is 5~80wt%；
The content of rhodioside is 5~80wt% in the gadol extract；
The content of organic acid is 5~80wt% in the Saussurea involucrata extract；
The purity of the carnosine is 90-100%；
5~40wt% of content of polysaccharide in the saccharomycete/rice fermentation liquid.
5. having effects that the plant composition of Vitamin K, eye pouch of dispelling as claimed in claim 3, which is characterized in that be logical
Following processing step is crossed to be made:
1) it is weighed respectively according to following weight: 5~50 parts of Honegsukle flower P.E, 5~90 parts of gadol extract, saussurea involucrata
5~50 parts of extract and 1~20 part of carnosine and saccharomycete/10~90 parts of rice fermentation liquid；
2) raw material in step 1) is merged, adds heating, ultrasound or stirring after 10~100 parts of water and 5~60 parts of dihydric alcohol,
Make sufficiently to dissolve；
3) extracting solution for obtaining step 2) is filtered or is centrifuged, and obtains corresponding extracting solution；
4) step 3) obtain extracting solution in preservative is added, stir evenly to get have effects that Vitamin K, eye pouch of dispelling
Plant composition.
6. the plant composition with Vitamin K, eye pouch of dispelling of any of claims 1-5 is in external application shield
Application in skin product, it is characterised in that:
By have effects that Vitamin K dispel eye pouch external use skin care gross mass on the basis of, contain in the external use skin care
The plant composition of 0.5~10wt% and 90%~95.5% external use skin care field customary adjuvant.
7. application as claimed in claim 6, it is characterised in that: the customary adjuvant is selected from emulsifier, surfactant, moisturizing
Agent, solubilizer, thickener, skin conditioning agent, moisturizer, pH adjusting agent, preservative, chelating agent, essence, deionized water one kind
Or a variety of mixing.
8. application as claimed in claim 6, it is characterised in that: the external use skin care is face cream, facial mask, Essence, lotion
Or aqua.
9. application as claimed in claim 8, it is characterised in that: the lotion is by the raw material system of following mass percentage
At:
A phase raw material: EDTA-2Na 0.1~0.3%, carbomer 0.2~1%, glycerol 1~5%, panthenol 0.1~1%, trehalose
1~2%, 1,3-BDO 2~4% has effects that Vitamin K is dispelled the plant prescription 1~8% of eye pouch, water 60~80%；
B phase raw material: PEG-100 stearate 1~3%, cetostearyl alcohol 0.5~1.5%, tristerin 0.5~1%,
Polyisobutene 2~7%, caprylic capric glyceryl ester 1~5%, Butyrospermum parkii 0.5~3%, isohexadecane 2~7%；
C phase raw material: 10%NaOH 0.4~2.5%, preservative 0.1~0.2%.
10. application as claimed in claim 9, which is characterized in that the lotion is through the following steps that be made:
1) it adds water in kettle, carbomer is added, impregnate 10min, heating stirring is whole to raw material at a temperature of 80~85 DEG C
Dissolution is complete；
2) A phase raw material is continuously added, keeping the temperature 80~85 DEG C of stirrings, all dissolution completely, obtains A after heat preservation 10min sterilizing to raw material
Phase feedstock processing object is kept the temperature spare；
3) B phase raw material is added in oily phase pot, 80~85 DEG C of agitating and heating dissolutions completely, are kept the temperature spare；
4) A phase feedstock processing object obtained in step 2) is pumped into emulsion pot, B phase raw material is pumped under homogeneous stirring and is emulsified
In pot, start to cool down after homogeneous 5min, stirring heat preservation 10min；
5) when temperature drops to 40~45 DEG C, C phase raw material is added in emulsion pot, discharges, is obtained with light after mixing evenly
Change black eye to dispel the lotion of eye pouch effect.
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| CN201910618821.4A CN110179735A (en) | 2019-07-10 | 2019-07-10 | Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care |
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| CN201910618821.4A CN110179735A (en) | 2019-07-10 | 2019-07-10 | Have effects that Vitamin K, the plant composition for eye pouch of dispelling and its application in external use skin care |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023170311A1 (en) * | 2022-03-11 | 2023-09-14 | Progelife | Anti-aging compositions |
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