CN112076298A - Ginseng and rhizoma polygonati cream and preparation method and application thereof - Google Patents

Ginseng and rhizoma polygonati cream and preparation method and application thereof Download PDF

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Publication number
CN112076298A
CN112076298A CN202011023939.1A CN202011023939A CN112076298A CN 112076298 A CN112076298 A CN 112076298A CN 202011023939 A CN202011023939 A CN 202011023939A CN 112076298 A CN112076298 A CN 112076298A
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parts
ginseng
rhizoma polygonati
stomach
raw materials
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李学武
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Xi'an Lianhu Wuchao Jiuti National Medical Center Co ltd
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Xi'an Lianhu Wuchao Jiuti National Medical Center Co ltd
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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Abstract

The invention discloses ginseng and rhizoma polygonati cream which is prepared from the following raw materials: ginseng, rhizoma polygonati, Chinese yam, gordon euryale seed, endothelium corneum gigeriae galli, poria cocos, dried orange peel, liquorice, stir-fried hyacinth bean, malt, scorched hawthorn fruit, sea-buckthorn, fructus amomi, radish seed, dandelion, polygonatum odoratum, fingered citron, lily, walnut kernel, black sesame, donkey-hide gelatin, honey and yellow wine. The invention also discloses a preparation method of the ginseng and rhizoma polygonati cream. The components in the formula are precise in compatibility, simple in medicine taking, moderate in reinforcing and reducing, mild in medicine property, and complementary to each other, and play a role in invigorating the stomach and nourishing the stomach, wherein the Chinese yam, the poria cocos and the ginseng are used for invigorating the spleen and tonifying qi, the gorgon fruit is used for transforming qi, promoting diuresis and drying dampness, the endothelium corneum gigeriae galli, the malt and the hawthorn contain digestive enzymes, the sea buckthorn has the functions of invigorating the spleen, nourishing the stomach, helping digestion, promoting blood circulation and removing blood stasis, and the components are used in a matched mode, so that the purposes of nourishing the stomach and conditioning the spleen and stomach can be achieved, the recovery of the stomach illness.

Description

Ginseng and rhizoma polygonati cream and preparation method and application thereof
Technical Field
The invention relates to the field of health-care food, in particular to ginseng and rhizoma polygonati cream as well as a preparation method and application thereof.
Background
China is a large country with stomach illness, people suffering from stomach illness account for 42 percent of the total population on average, more than half of people are thought to suffer from different stomach illness, and the theory that 'ten people and nine stomach illness' exist among people is common. The stomach diseases are characterized by 'three-fending seven-nourishing', which fully indicates that the root of the stomach diseases treatment lies in nourishing the stomach, and the best method for nourishing the stomach is to take the traditional Chinese medicine health food. However, the traditional Chinese medicine health-care foods on the market at present are few, the hawthorn cake, the poria cake, the clove tea, the sea-buckthorn tea and the like are common, the traditional Chinese medicines are designed to supplement and play a role together, and the purpose of conditioning the body is achieved.
Disclosure of Invention
The invention aims to solve the problems of stomach nourishing and poor stomach disease treatment effects of traditional Chinese medicine health-care food in the prior art, and provides ginseng and rhizoma polygonati paste and a preparation method and application thereof.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows: a ginseng and rhizoma polygonati cream is prepared from the following raw materials: ginseng, rhizoma polygonati, Chinese yam, gordon euryale seed, endothelium corneum gigeriae galli, poria cocos, dried orange peel, liquorice, stir-fried hyacinth bean, malt, scorched hawthorn fruit, sea-buckthorn, fructus amomi, radish seed, dandelion, polygonatum odoratum, fingered citron, lily, walnut kernel, black sesame, donkey-hide gelatin, honey and yellow wine.
Preferably, the feed consists of the following raw materials in parts by weight: 7-12 parts of ginseng, 8-12 parts of rhizoma polygonati, 10-14 parts of Chinese yam, 4-8 parts of gordon euryale seed, 18-25 parts of endothelium corneum gigeriae galli, 13-18 parts of poria cocos, 10-15 parts of dried orange peel, 4-9 parts of liquorice, 10-15 parts of fried hyacinth bean, 10-15 parts of malt, 8-13 parts of scorched hawthorn fruit, 13-18 parts of sea-buckthorn, 4-8 parts of fructus amomi, 13-16 parts of semen raphani, 3-19 parts of dandelion, 7-11 parts of radix polygonati officinalis, 6-10 parts of fingered citron, 11-18 parts of lily, 8-13 parts of walnut kernel, 3-7 parts of black sesame, 18-22 parts of donkey-hide gelatin, 18-23 parts of honey and 15.
The invention also provides a preparation method of the ginseng and rhizoma polygonati cream, which comprises the following steps:
s1, weighing the raw materials according to the formula, and pulverizing walnut kernels and black sesame in the raw materials to obtain walnut kernel and black sesame mixed powder;
s2, melting colla Corii Asini in the raw materials with yellow wine;
s3, grinding rhizoma polygonati in the raw materials into powder, adding ginseng, mixing and decocting for 20 minutes, and taking rhizoma polygonati and ginseng decoction;
s4, adding 8-10 times of water into Chinese yam, semen euryales, endothelium corneum gigeriae galli, poria cocos, pericarpium citri reticulatae, liquorice, stir-fried hyacinth beans, malt, scorched hawthorn fruits, sea buckthorn, fructus amomi, semen raphani, dandelion, radix polygonati officinalis, fingered citron and lily in the raw materials to soak for 12 hours to obtain a soaking mixture;
s4, decocting the soaked mixture in the step S4 twice, combining the decocted liquid medicines for two times, precipitating, sieving the precipitated liquid medicine with a sieve of 80-100 meshes, adding the sealwort and ginseng decoction, uniformly mixing, decocting and concentrating with strong fire, and filtering again with a sieve of 100 meshes when the concentrated liquid is in a state close to paste collection to obtain concentrated liquid;
s5, uniformly mixing the concentrated solution obtained in the step S4, the walnut kernel and black sesame mixed powder obtained in the step S1 and the yellow wine melted by the donkey-hide gelatin and the honey obtained in the step S2, concentrating the mixture by slow fire, and cooling the mixture at room temperature.
Preferably, in step S4, the two-time decoction specifically includes: boiling the soaked mixture, decocting for 1 hr, and separating to obtain first medicinal liquid and residue; adding 5-6 times of water into the residue, decocting for 30-45 min, and collecting the second medicinal liquid.
The invention also provides application of the ginseng and rhizoma polygonati paste in preparing a medicine for treating chronic gastritis.
The invention also provides application of the ginseng and rhizoma polygonati paste in preparing a medicine for treating atrophic gastritis.
The invention also provides application of the ginseng and rhizoma polygonati paste in preparing a medicine for treating bile reflux.
The invention also provides application of the ginseng and rhizoma polygonati paste in preparing a medicine for treating insomnia.
Ginseng: sweet and slightly cold in flavor, it enters spleen, stomach and lung meridians. Modern researches have shown that ginseng contains various ginsenoside and polysaccharide components, and has the effects of invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, and tranquilizing mind. According to clinical observation, for patients with chronic gastritis accompanied with achlorhydria or achlorhydria, the stomach-receiving capacity is increased and the symptoms are relieved or disappeared after the ginseng is taken. Ginseng has also been reported to cause the disappearance of stomachache, the enhancement of appetite, the normal defecation and the increase of total acidity of gastric juice in patients with chronic gastritis.
Rhizoma polygonati: rhizome of Polygonatum sibiricum contains steroid saponin, and 2 furostanol type saponins and 2 spirostanol type saponins are separated. The sealwort polysaccharide A, B, C contains glucose, mannose and galacturonic acid, and sealwort oligosaccharide A, B, C, mainly has the functions of invigorating spleen and nourishing kidney yin, promotes the recovery of gastrointestinal function and improves the constitution of human body by tonifying spleen and kidney, and sealwort and Chinese yam are jointly used for moistening the body fluid of spleen and lung.
Tuckahoe, poria cocos: eliminating dampness and promoting diuresis; strengthening the spleen and stomach; tranquilizing mind. Poria can be used as adjuvant drug for tonifying lung and spleen and treating qi deficiency. Modern research: poria has direct relaxation effect on rabbit isolated intestinal canal, and can be used for preventing ulcer formed by rat pylorus ligation and reducing gastric acid.
Yam has the effects of tonifying kidney-qi, strengthening spleen and stomach, relieving diarrhea and dysentery, resolving paralysis and saliva, and moistening fur. Research in recent years shows that the Chinese yam has the effects of inducing the generation of interferon and enhancing the immune function of human bodies. The choline and the lecithin contained in the health-care food are helpful for improving the memory of people, can build the body and delay aging after being frequently eaten, and are good health-care products favored by people.
Dandelion: sweet in flavor and cold in nature, entering liver and stomach meridians. Has the effects of clearing away heat and toxic materials, eliminating carbuncle and resolving hard mass. Modern research contains xanthofural, vitamin B2, various kinds of terpineol, inositol, asparagine, bitter substance, saponin, resin, inulin, pectin, choline, etc. Has good stomach invigorating effect, and has different degrees of protective effect on rat gastric mucosa injury model observation caused by absolute ethyl alcohol and rat gastric ulcer model observation by rat emergency method and ligation method with dandelion.
In the formula, the ginseng, the poria cocos, the fried hyacinth bean, the Chinese yam, the gordon euryale seed and the liquorice have the spleen tonifying effect;
according to the formula, the dried orange peel, the fructus amomi and the fingered citron have the effects of tonifying spleen and regulating qi.
The chicken's gizzard-membrane, the malt, the scorched hawthorn fruit, the radish seed and the sea-buckthorn in the formula have the effects of tonifying spleen and eliminating food retention.
In the formula of the invention, the sealwort, the yam, the lily, the walnut kernel and the black sesame have the effects of nourishing yin and tonifying kidney.
The dandelion in the formula has the effects of clearing away heat and toxic materials, disinfecting and resolving masses and resolving food toxicity.
The donkey-hide gelatin and the honey in the formula have the effects of enriching blood, moistening dryness, tonifying qi and nourishing spleen.
In conclusion, the components in the formula are all medicinal and edible, the compatibility is strict, the medicine taking is simplified, the reinforcing and reducing are moderate, the medicine properties are mild, the components supplement each other, the effects of invigorating the stomach and nourishing the stomach are exerted together, the aims of nourishing the stomach and conditioning the spleen and stomach can be achieved, the rehabilitation of the stomach disease is promoted, and the obvious treatment effect on the stomach disease is achieved.
The invention has the following beneficial effects:
firstly), the components in the formula are precise in compatibility, simple in medicine taking, moderate in reinforcing and reducing, mild in medicine property, and complementary to each other, and play a role in invigorating the stomach and nourishing the stomach, wherein the Chinese yam, the poria cocos, the ginseng invigorate the spleen and tonify qi, the gorgon fruit is capable of transforming qi, promoting diuresis and drying dampness, the endothelium corneum gigeriae galli, the malt and the hawthorn contain digestive enzymes, and the sea buckthorn has the functions of invigorating the spleen, nourishing the stomach, helping digestion, promoting blood circulation and removing blood stasis.
And secondly), all the components in the formula are homologous in medicine and food, can be eaten for a long time, and have no toxic or side effect on a human body.
Thirdly), the raw materials in the formula are prepared into the paste, so that the paste is convenient to take, good in taste and easy to absorb.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
Weighing the following raw materials according to a formula: 12 parts of ginseng, 10 parts of rhizoma polygonati, 14 parts of Chinese yam, 6 parts of gordon euryale seed, 18 parts of endothelium corneum gigeriae galli, 18 parts of poria cocos, 15 parts of dried orange peel, 5 parts of liquorice, 10 parts of fried hyacinth bean, 12 parts of malt, 8 parts of scorched hawthorn fruit, 18 parts of sea-buckthorn, 5 parts of fructus amomi, 14 parts of radish seed, 3 parts of dandelion, 9 parts of polygonatum odoratum, 6 parts of fingered citron, 11 parts of lily, 13 parts of walnut kernel, 3 parts of black sesame, 22 parts of donkey-hide gelatin, 18 parts of honey and 25.
Pulverizing semen Juglandis and semen Sesami Niger to obtain semen Juglandis and semen Sesami Niger mixed powder; melting colla Corii Asini with yellow wine; pulverizing rhizoma Polygonati, adding Ginseng radix, decocting for 20 min, and collecting rhizoma Polygonati and Ginseng radix decoction.
Soaking rhizoma Dioscoreae, semen euryales, endothelium corneum Gigeriae Galli, Poria, pericarpium Citri Tangerinae, Glycyrrhrizae radix, parched semen lablab album, fructus Hordei Germinatus, fructus crataegi preparata, fructus Hippophae, fructus Amomi, Raphani semen, herba Taraxaci, rhizoma Polygonati Odorati, fructus Citri Sarcodactylis, and Bulbus Lilii in 8 times of water for 12 hr to obtain soaking mixture; boiling the soaked mixture, decocting for 1 hr, and separating to obtain first medicinal liquid and residue; adding 5 times of water into the dregs of a decoction, decocting for 45 minutes, taking the second liquid medicine, combining the liquid medicines decocted twice, precipitating, sieving the precipitated liquid medicine with a 100-mesh sieve, adding the sealwort and ginseng decoction, uniformly mixing, decocting with strong fire, concentrating, and filtering again with the 100-mesh sieve when the concentrated liquid medicine is in a state close to paste collection to obtain the concentrated liquid.
Mixing the concentrated solution, semen Juglandis and semen Sesami Niger mixed powder, yellow wine melted colla Corii Asini and Mel, concentrating with slow fire, and cooling at room temperature to obtain Ginseng radix rhizoma Polygonati extract.
Example 2
Weighing the following raw materials according to a formula: 7 parts of ginseng, 12 parts of rhizoma polygonati, 10 parts of Chinese yam, 4 parts of gordon euryale seed, 20 parts of endothelium corneum gigeriae galli, 15 parts of poria cocos, 12 parts of dried orange peel, 9 parts of liquorice, 13 parts of fried hyacinth bean, 10 parts of malt, 10 parts of scorched hawthorn fruit, 15 parts of sea-buckthorn, 4 parts of fructus amomi, 16 parts of radish seed, 9 parts of dandelion, 7 parts of polygonatum odoratum, 10 parts of fingered citron, 13 parts of lily, 10 parts of walnut kernel, 5 parts of black sesame, 20 parts of donkey-hide gelatin, 20 parts of honey and 15.
Pulverizing semen Juglandis and semen Sesami Niger to obtain semen Juglandis and semen Sesami Niger mixed powder; melting colla Corii Asini with yellow wine; pulverizing rhizoma Polygonati, adding Ginseng radix, decocting for 20 min, and collecting rhizoma Polygonati and Ginseng radix decoction.
Soaking rhizoma Dioscoreae, semen euryales, endothelium corneum Gigeriae Galli, Poria, pericarpium Citri Tangerinae, Glycyrrhrizae radix, parched semen lablab album, fructus Hordei Germinatus, fructus crataegi preparata, fructus Hippophae, fructus Amomi, Raphani semen, herba Taraxaci, rhizoma Polygonati Odorati, fructus Citri Sarcodactylis, and Bulbus Lilii in 10 times of water for 12 hr to obtain soaking mixture; boiling the soaked mixture, decocting for 1 hr, and separating to obtain first medicinal liquid and residue; adding 5 times of water into the dregs of a decoction, decocting for 30 minutes, taking the second liquid medicine, combining the liquid medicines decocted twice, precipitating, sieving the precipitated liquid medicine with a 80-mesh sieve, adding the sealwort and ginseng decoction, uniformly mixing, decocting with strong fire, concentrating, and filtering again with a 100-mesh sieve when the concentrated liquid medicine is in a state close to paste collection to obtain the concentrated liquid.
Mixing the concentrated solution, semen Juglandis and semen Sesami Niger mixed powder, yellow wine melted colla Corii Asini and Mel, concentrating with slow fire, and cooling at room temperature to obtain Ginseng radix rhizoma Polygonati extract.
Example 3
Weighing the following raw materials according to a formula: 11 parts of ginseng, 8 parts of rhizoma polygonati, 12 parts of Chinese yam, 8 parts of gordon euryale seed, 25 parts of chicken's gizzard-membrane, 13 parts of poria cocos, 10 parts of dried orange peel, 4 parts of liquorice, 15 parts of fried hyacinth bean, 15 parts of malt, 13 parts of scorched hawthorn fruit, 13 parts of sea-buckthorn, 8 parts of fructus amomi, 13 parts of radish seed, 19 parts of dandelion, 11 parts of polygonatum odoratum, 8 parts of fingered citron, 18 parts of lily, 8 parts of walnut kernel, 7 parts of black sesame, 18 parts of donkey-hide gelatin, 23 parts of honey.
Pulverizing semen Juglandis and semen Sesami Niger to obtain semen Juglandis and semen Sesami Niger mixed powder; melting colla Corii Asini with yellow wine; pulverizing rhizoma Polygonati, adding Ginseng radix, decocting for 20 min, and collecting rhizoma Polygonati and Ginseng radix decoction.
Soaking rhizoma Dioscoreae, semen euryales, endothelium corneum Gigeriae Galli, Poria, pericarpium Citri Tangerinae, Glycyrrhrizae radix, parched semen lablab album, fructus Hordei Germinatus, fructus crataegi preparata, fructus Hippophae, fructus Amomi, Raphani semen, herba Taraxaci, rhizoma Polygonati Odorati, fructus Citri Sarcodactylis, and Bulbus Lilii in 9 times of water for 12 hr to obtain soaking mixture; boiling the soaked mixture, decocting for 1 hr, and separating to obtain first medicinal liquid and residue; adding 6 times volume of water into the dregs of a decoction, decocting for 40 minutes, taking the second liquid medicine, combining the liquid medicines decocted twice, precipitating, sieving the precipitated liquid medicine with a 100-mesh sieve, adding the sealwort and ginseng decoction, uniformly mixing, decocting with strong fire, concentrating, and filtering again with the 100-mesh sieve when the concentrated liquid medicine is in a state close to paste collection to obtain the concentrated liquid.
Mixing the concentrated solution, semen Juglandis and semen Sesami Niger mixed powder, yellow wine melted colla Corii Asini and Mel, concentrating with slow fire, and cooling at room temperature to obtain Ginseng radix rhizoma Polygonati extract.
In the embodiment, auxiliary materials are also added, and the auxiliary materials are auxiliary materials conventionally used in the field.
Example 4
The ginseng and rhizoma polygonati cream prepared according to the embodiment 1 of the invention is used for treating chronic gastritis.
Example 5
The ginseng radix polygonati cream prepared according to the embodiment 1 of the invention is added with oldenlandia diffusa, barbed skullcap herb, zedoary, folium cycas and akebia fruit to be used for treating atrophic gastritis.
Example 6
The ginseng radix polygonati cream prepared according to the invention in example 2 is used for treating bile reflux together with the lysimachia christinae and the curcuma aromatica.
Example 7
The ginseng and rhizoma polygonati paste prepared according to the embodiment 3 of the invention is added with fried jujube kernels for treating insomnia.
The invention is used for testing the treatment effect of the stomach illness
Test subjects: 100 patients with gastropathy, wherein 51 male patients and 49 female patients have the age distribution of 32-76 years and the course of disease is 3-34 years, and the patients with gastropathy are diagnosed by gastroscopy.
The test method comprises the following steps: the patient takes the ginseng and rhizoma polygonati cream prepared in the embodiment 1 of the invention once in the morning and at night, takes the ginseng and rhizoma polygonati cream on an empty stomach, and takes 10g of the ginseng and rhizoma polygonati cream each time; the medicine is taken for three months as a course of treatment and is continuously taken for two courses of treatment.
Symptom observation indexes are as follows: observe stomach ache, scorching heat, acid regurgitation, belching, anorexia, emesis, tiredness, debilitation, abnormal stool, sleep and tongue fur pulse. Gastroscope observation indexes are as follows: mainly observe the change of gastric mucosa before and after gastroscopy and pathological treatment.
The criteria for therapeutic effect are as follows:
the effect is shown: the clinical symptoms such as stomachache, burning heat, acid regurgitation, belching, anorexia, emesis, tiredness, hypodynamia, abnormal stool and the like disappear; the gastritis, the intestinal metaplasia and the hyperplasia disappear through gastroscopy, and the atypical hyperplasia disappears.
The method has the following advantages: relieving clinical symptoms such as stomach ache, scorching heat, acid regurgitation, belch, anorexia, emesis, tiredness, debilitation, abnormal stool, etc.; the gastritis, the intestinal metaplasia and the hyperplasia are reduced by gastroscopy.
And (4) invalidation: the clinical symptoms and the gastroscopy result are not obviously improved.
And (3) test results: after two treatment courses, the effect is obvious for 55 cases; effective 42 cases; and 3 cases of invalidation. The test results show that the traditional Chinese medicine composition has an obvious treatment effect on stomach diseases, is convenient to take and has no toxic or side effect on human bodies.
Clinical typical cases
Sunjiao, female, age 38, married, white collar, work in Xian City. The doctor visits 3 months and 5 days in 2017. Mainly complaining of stomachache, acid regurgitation, anorexia and hypodynamia for 3 years, aggravating for 6 months. The patient has suffered from stomachache and sour regurgitation after eating cold, cool and spicy food 3 years ago, and has taken western medicine for inhibiting acid, but has repeated attack after stopping taking the medicine. It has been increasingly emphasized for half a year. The symptoms of stomachache, acid regurgitation, anorexia, hypodynamia, difficulty in falling asleep and loose stool are treated twice a day. Gastroscopy: chronic superficial gastritis. Helicobacter pylori examination of breath (yin). And (3) Western diagnosis: chronic superficial gastritis, functional dyspepsia. Traditional Chinese medicine diagnosis: weakness of the spleen and stomach. Treatment: taking the ginseng and rhizoma polygonati cream prepared in the embodiment 1 of the invention twice a day, 10g each time; after two treatment courses of continuous administration, the disease disappears after 6 months. Stomachache does not appear in the latter half of the period of stopping taking the medicine, the appetite is recovered, the physical strength is normal, the sleep is obviously improved, and the stool is normal.
Wang somebody, man, 65 years old. Shanxi blue field people. First diagnosis in 2016, 1 month and 20 days. Chief complaints about the fullness and pain of the stomach, anorexia for 4 years, aggravated by a month. Before 4 years, patients have epigastric discomfort, fullness, dull pain, belching, anorexia, vexation, hypodynamia, poor sleep, frequent stool shaping, obvious intolerance of cold, sallow complexion, listlessness, pale tongue, swollen white fur and deep pulse due to improper diet. Gastroscopy: (antrum of the stomach) mucosa severe chronic inflammation, moderate atrophy, moderate intestinal metaplasia. And (3) Western diagnosis: chronic atrophic gastritis (moderate) with enterogenization (moderate); traditional Chinese medicine diagnosis: the spleen and stomach are weak, and the stomach-qi goes upwards reversely. Treatment: taking the ginseng and rhizoma polygonati cream prepared in the embodiment 2 of the invention twice a day, 10g each time, and taking oldenlandia diffusa, barbed skullcap herb, zedoary, folium aconiti szechenyiani and akebia fruit together; two treatment courses are continuously taken, namely 6 months. The symptoms are obviously relieved, the fullness is relieved, the appetite is increased, the eructation is reduced, the pain frequency is reduced, the stool is formed, and the spirit and the physical strength are obviously improved.
Zhao somesome, woman 56 years old. Shanxi province, copper city. The physician needs to take a doctor in 17 years, 6 months and 8 months after the patient suffers from anorexia, stomach ache, gastrectasia, hiccup and acid regurgitation for 12 years. Chief complaints about anorexia, heartburn, dull pain in the stomach, fullness and distention, poor sleep, irregular stool, and dry stool. The heartburn of western medicines is relieved, but the fullness and dull pain are not reduced, and the curative effect of the traditional Chinese medicines is not satisfactory. The complexion is sallow and lusterless, and the body is emaciated. Swollen tongue with teeth marks, white coating and deep and thready pulse. Gastroscopy: chronic superficial-atrophic gastritis. Treatment: the ginseng and rhizoma polygonati cream prepared in the embodiment 3 is taken 10g each time twice a day for 6 months. The symptoms are relieved, stomachache is improved, hiccups are obviously reduced, flatulence and acid regurgitation are relieved, and stool is normal once a day. After the oral liquid is taken for 3 months, the diet is recovered to be normal, the stomach pain and the stomach distension are cured, the hiccup is obviously relieved, the sleep is improved, the weight is increased, the face color is better, and the stool is normal.
The present description is to be considered as illustrative and not restrictive, and it is within the scope of the present invention that certain changes and modifications may be made in the details of the invention without departing from the spirit and scope of the invention.

Claims (8)

1. The ginseng and rhizoma polygonati cream is characterized by comprising the following raw materials: ginseng, rhizoma polygonati, Chinese yam, gordon euryale seed, endothelium corneum gigeriae galli, poria cocos, dried orange peel, liquorice, stir-fried hyacinth bean, malt, scorched hawthorn fruit, sea-buckthorn, fructus amomi, radish seed, dandelion, polygonatum odoratum, fingered citron, lily, walnut kernel, black sesame, donkey-hide gelatin, honey and yellow wine.
2. The ginseng radix polygonati cream according to claim 1 is characterized by comprising the following raw materials in parts by weight: 7-12 parts of ginseng, 8-12 parts of rhizoma polygonati, 10-14 parts of Chinese yam, 4-8 parts of gordon euryale seed, 18-25 parts of endothelium corneum gigeriae galli, 13-18 parts of poria cocos, 10-15 parts of dried orange peel, 4-9 parts of liquorice, 10-15 parts of fried hyacinth bean, 10-15 parts of malt, 8-13 parts of scorched hawthorn fruit, 13-18 parts of sea-buckthorn, 4-8 parts of fructus amomi, 13-16 parts of semen raphani, 3-19 parts of dandelion, 7-11 parts of radix polygonati officinalis, 6-10 parts of fingered citron, 11-18 parts of lily, 8-13 parts of walnut kernel, 3-7 parts of black sesame, 18-22 parts of donkey-hide gelatin, 18-23 parts of honey and 15.
3. The preparation method of the ginseng and rhizoma polygonati cream is characterized by comprising the following steps:
s1, weighing the raw materials according to the formula, and pulverizing walnut kernels and black sesame in the raw materials to obtain walnut kernel and black sesame mixed powder;
s2, melting colla Corii Asini in the raw materials with yellow wine;
s3, grinding rhizoma polygonati in the raw materials into powder, adding ginseng, mixing and decocting for 20 minutes, and taking rhizoma polygonati and ginseng decoction;
s4, adding 8-10 times of water into Chinese yam, semen euryales, endothelium corneum gigeriae galli, poria cocos, pericarpium citri reticulatae, liquorice, stir-fried hyacinth beans, malt, scorched hawthorn fruits, sea buckthorn, fructus amomi, semen raphani, dandelion, radix polygonati officinalis, fingered citron and lily in the raw materials to soak for 12 hours to obtain a soaking mixture;
s4, decocting the soaked mixture in the step S4 twice, combining the decocted liquid medicines for two times, precipitating, sieving the precipitated liquid medicine with a sieve of 80-100 meshes, adding the sealwort and ginseng decoction, uniformly mixing, decocting and concentrating with strong fire, and filtering again with a sieve of 100 meshes when the concentrated liquid is in a state close to paste collection to obtain concentrated liquid;
s5, uniformly mixing the concentrated solution obtained in the step S4, the walnut kernel and black sesame mixed powder obtained in the step S1 and the yellow wine melted by the donkey-hide gelatin and the honey obtained in the step S2, concentrating the mixture by slow fire, and cooling the mixture at room temperature.
4. The method for preparing the ginseng and rhizoma polygonati cream according to claim 3, wherein in the step S4, the two decoction steps are as follows: boiling the soaked mixture, decocting for 1 hr, and separating to obtain first medicinal liquid and residue; adding 5-6 times of water into the residue, decocting for 30-45 min, and collecting the second medicinal liquid.
5. The use of the ginseng and polygonatum paste according to any one of claims 1 to 4 in the preparation of a medicament for treating chronic gastritis.
6. The use of the ginseng and polygonatum paste according to any one of claims 1 to 4 in the preparation of a medicament for treating atrophic gastritis.
7. The use of the ginseng polygonatum cream according to any one of claims 1 to 4 in the preparation of a medicament for treating bile reflux.
8. The use of the ginseng and polygonatum sibiricum paste according to any one of claims 1 to 4 in the preparation of a medicament for treating insomnia.
CN202011023939.1A 2020-09-25 2020-09-25 Ginseng and rhizoma polygonati cream and preparation method and application thereof Pending CN112076298A (en)

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CN112890180A (en) * 2021-03-04 2021-06-04 北京汉后中医研究院 Donkey-hide gelatin, sea cucumber and polygonatum odoratum paste and preparation method thereof
CN113318204A (en) * 2021-06-07 2021-08-31 云南中医药大学 Compound fructus amomi tea for enhancing gastrointestinal motility function and preparation method thereof
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CN113951505A (en) * 2021-02-19 2022-01-21 北京鹤年堂中医医院管理(集团)有限公司 Donkey-hide gelatin red ginseng paste and preparation method thereof
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CN114794458A (en) * 2022-03-09 2022-07-29 北京仲伊本草科技有限公司 Ginseng and radix polygonati fine food pill and preparation method thereof
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CN113951505A (en) * 2021-02-19 2022-01-21 北京鹤年堂中医医院管理(集团)有限公司 Donkey-hide gelatin red ginseng paste and preparation method thereof
CN112890180A (en) * 2021-03-04 2021-06-04 北京汉后中医研究院 Donkey-hide gelatin, sea cucumber and polygonatum odoratum paste and preparation method thereof
CN113318204A (en) * 2021-06-07 2021-08-31 云南中医药大学 Compound fructus amomi tea for enhancing gastrointestinal motility function and preparation method thereof
CN113694162A (en) * 2021-09-10 2021-11-26 哈尔滨物粹堂药业有限公司 Traditional Chinese medicine formula for conditioning body functions
CN114404518A (en) * 2022-02-08 2022-04-29 和也健康科技有限公司 Spleen-tonifying and lung-benefiting paste formula and preparation process thereof
CN114404518B (en) * 2022-02-08 2024-01-02 和也健康科技有限公司 Spleen-tonifying and lung-benefiting paste prescription and preparation process thereof
CN114794458A (en) * 2022-03-09 2022-07-29 北京仲伊本草科技有限公司 Ginseng and radix polygonati fine food pill and preparation method thereof
CN114868920A (en) * 2022-05-26 2022-08-09 金华市食品药品检验检测研究院 Lotus seed kidney-tonifying and spleen-invigorating paste and preparation method thereof
CN115105575A (en) * 2022-07-14 2022-09-27 中山市中智药业集团有限公司 Chinese yam and rhizoma polygonati herbal composition, Chinese yam and rhizoma polygonati wall-broken herbal tea substitute and preparation method thereof
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