CN112741324A

CN112741324A - Ginseng and rhizoma polygonati cream and preparation method thereof

Info

Publication number: CN112741324A
Application number: CN202110188542.6A
Authority: CN
Inventors: 曹希久; 张大宁
Original assignee: Beijing Heniantang Traditional Chinese Medicine Hospital Management Group Co ltd
Current assignee: Beijing Heniantang Traditional Chinese Medicine Hospital Management Group Co ltd
Priority date: 2021-02-19
Filing date: 2021-02-19
Publication date: 2021-05-04

Abstract

The invention provides ginseng and rhizoma polygonati cream and a preparation method thereof. The ginseng and rhizoma polygonati cream comprises a concentrated solution and auxiliary materials, wherein the concentrated solution is prepared by decocting raw materials in water and concentrating, and the raw materials comprise the following components in parts by weight: 155 portions of sun-dried ginseng 145-containing materials, 310 portions of sealwort 290-containing materials, 75-85 portions of polygonatum odoratum, 160 portions of fingered citron 140-containing materials, 125 portions of Chinese yam 115-containing materials and 210 portions of Chinese date 190-containing materials are artificially planted for 4-5 years. The ginseng and rhizoma polygonati cream disclosed by the invention is prepared according to the requirement of four-time conditioning, and the formula is used for supplementing qi, nourishing yin and tonifying deficiency of viscera, so that the ginseng and rhizoma polygonati cream has universality; in addition, the ginseng and rhizoma polygonati cream has high material selection standard and scientific and rigorous boiling process, the drug effect of each raw material can be completely extracted, and the product has the advantages of good cream forming property, high drug effect, difficult deterioration, long storage time and the like.

Description

Ginseng and rhizoma polygonati cream and preparation method thereof

Technical Field

The invention relates to the technical field of health-care food, in particular to ginseng and rhizoma polygonati paste and a preparation method thereof.

Background

Deficiency syndrome is the symptom of weakened disease resistance and hypophysiology caused by deficiency of vital qi, and is mainly manifested by pale face and lips, listlessness, palpitation, short breath, spontaneous perspiration, night sweat, loose stool, frequent micturition, tender tongue without fur, weak pulse, etc. Deficiency syndrome can be divided into four types of qi deficiency, blood deficiency, yin deficiency and yang deficiency, wherein qi deficiency and yang deficiency indicate the decline of the activity ability of the body, yin deficiency and blood deficiency indicate the loss of essence, blood and body fluids of the body, and both qi and blood deficiency and both yin and yang deficiency are common syndromes.

Qi deficiency is mainly manifested by fatigue, lassitude, short breath, easy sweating, dizziness, palpitation, sallow complexion, inappetence, spontaneous sweating due to asthenic fever, pale and swollen tongue with teeth marks on the edge of tongue, weak pulse, etc.; it is usually caused by congenital deficiency, acquired malnutrition, overstrain, chronic disease, or hypofunction of the lung, spleen and kidney. The blood deficiency mainly turns into sallow and pale complexion, pale color of lips, tongue, nails, dizziness, palpitation, insomnia, dreaminess, numb hands and feet, little color and light color during menstrual period, slippery tongue coating, little saliva, thready and weak pulse and the like; it is caused by improper diet, overstrain, emotional distress, excessive blood loss, and chronic illness. Yin deficiency is usually caused by blood deficiency, and yin deficiency generates internal heat, commonly called deficient fire; it is mainly manifested as low fever, irritability, feverish sensation in the palms and soles, dry mouth, dry throat, dry stool, scanty or yellow urine, night sweat, vexation, insomnia, dizziness, tinnitus, red tongue with little coating, and thready and rapid pulse. Yang deficiency, intolerance of cold, cold extremities, undigested food, lassitude, pale and swollen tongue with teeth marks, deep and thready pulse, etc.; it is usually caused by congenital deficiency, overstrain, improper diet, deficiency of qi and blood, and malnutrition after illness.

The traditional Chinese medicine theory is well balanced, the qi, blood, yin and yang of a human body are balanced and healthy, and the qi, blood, yin and yang are weak due to deficiency and need to be nourished; in view of this, the invention is particularly proposed.

Disclosure of Invention

The invention aims to provide ginseng sealwort ointment and a preparation method thereof, and the ginseng sealwort ointment has the effects of tonifying qi and yin, tonifying deficiency of internal organs and the like.

The invention provides a ginseng and rhizoma polygonati cream which comprises a concentrated solution and auxiliary materials, wherein the concentrated solution is prepared by decocting raw materials in water and concentrating, and the raw materials comprise the following components in parts by weight: 155 parts of sun-dried ginseng 145-containing materials, 310 parts of rhizoma polygonati 290-containing materials, 75-85 parts of polygonatum odoratum, 160 parts of fingered citron 140-containing materials, 125 parts of Chinese yam 115-containing materials and 210 parts of Chinese date 190-containing materials are artificially planted for 4-5 years; preferably, the raw materials comprise the following components in parts by weight: 150 parts of sun-dried ginseng, 300 parts of rhizoma polygonati, 80 parts of polygonatum odoratum, 150 parts of fingered citron, 120 parts of Chinese yam and 200 parts of Chinese date are artificially planted in 4-5 years.

The effects of the raw materials of the invention are as follows:

sun-dried ginseng: the product is prepared by cleaning and sun drying ginseng root, has effects of invigorating primordial qi, invigorating spleen, benefiting lung, promoting fluid production, and tranquilizing, and can be used for treating spleen qi deficiency, listlessness, debilitation, anorexia, loose stool, and syndromes such as lung qi deficiency, short breath, dyspnea, laziness in speaking, weak pulse, spontaneous perspiration, etc.; it also has the effects of benefiting qi for promoting production of body fluid, benefiting qi for tranquillization, benefiting qi for promoting production of blood, benefiting qi for controlling blood, invigorating qi for tonifying yang, and can be used for treating thirst and diabetes due to qi and fluid injury, palpitation, insomnia, amnesia due to deficiency of both qi and blood and uneasiness, blood deficiency syndrome, hemorrhage syndrome due to qi failing to control blood, impotence, etc.

Rhizoma polygonati: has the effects of tonifying qi and yin, strengthening spleen, moistening lung, tonifying kidney and the like, and is commonly used for spleen and stomach qi deficiency, tiredness and hypodynamia, stomach yin deficiency, dry mouth and poor appetite, lung deficiency and dry cough, overstrain cough and hemoptysis, essence and blood deficiency, soreness and weakness of waist and knees, early white beard and hair, internal heat and thirst quenching and the like.

Fragrant solomonseal rhizome: has the effects of nourishing yin, moistening dryness, promoting fluid production, quenching thirst, etc.; it is mainly used for treating dry cough with little phlegm due to yin deficiency and lung dryness, and can tonify stomach, promote fluid production to quench thirst, and treat fever impairment of body fluid, dysphoria with smothery sensation, thirst, diabetes, etc.; it is good at nourishing yin without affecting pathogen, and can be indicated for syndrome of yin deficiency with exogenous wind-heat.

Fingered citron: has the effects of soothing liver, regulating qi, harmonizing stomach, relieving pain, eliminating dampness and phlegm and the like; it is mainly used for treating qi stagnation of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach, anorexia, emesis, cough, excessive phlegm, etc.

Chinese yam: has the effects of supplementing qi and nourishing yin, tonifying spleen, lung and kidney, securing essence and stopping leukorrhagia, and the like, not only can tonify qi of spleen and stomach, but also can benefit yin of spleen and stomach, and is also astringent; it is commonly used for spleen and stomach deficiency, spleen deficiency with poor appetite, fatigue with loose stool, and diarrhea due to children dyspepsia; chronic cough and asthma due to lung deficiency or lung and kidney deficiency, nocturnal emission due to kidney deficiency, frequent micturition, clear and thin leukorrhea, lingering leukorrhea, etc.; it is also indicated for diabetes.

Chinese date: has the effects of tonifying spleen and stomach, benefiting qi for promoting production of body fluid, regulating yingfen and weifen, and relieving drug toxicity, and is mainly used for treating stomach deficiency and poor appetite, spleen weakness and loose stool, deficiency of qi, blood and body fluid, disharmony between ying and wei, palpitation and severe palpitation and the like.

In the ginseng and rhizoma polygonati cream, ginseng tonifies primordial qi to provide power for internal organs, is mild in nature and is mostly used for qi and yin deficiency patients, and tonifies spleen, benefits lung and spleen qi; the sealwort upper, middle and lower triple energizers are all nourished as ministers, and the sealwort upper, middle and lower triple energizers are used for tonifying qi, nourishing yin, moistening lung, strengthening spleen, tonifying kidney, tonifying spleen, spleen and stomach, and tonifying kidney, kidney and essence; rhizoma Polygonati Odorati has effects in nourishing yin, moistening dryness, promoting fluid production, quenching thirst, and treating yin deficiency of lung and stomach; the Chinese yam is used for tonifying qi and yin, not only tonifying qi of spleen and lung, but also benefiting yin of lung and kidney; the Chinese date has the effects of tonifying middle-jiao, benefiting qi, nourishing blood and calming nerves; the fingered citron has the effects of soothing liver-qi stagnation, regulating qi and reducing phlegm, is mainly used for treating qi stagnation of liver, spleen, lung and stomach, and is used as a guiding drug in the formula for specially regulating qi activity so as to ensure that all the drugs run smoothly in the body. The whole formula has the effects of tonifying qi, nourishing yin and tonifying deficiency of viscera.

The material selection standard of the invention for each raw material is as follows: the genuine medicinal materials grow naturally, are picked in full years and comply with the regulations. Genuine medicinal materials require that medicinal materials must come from medicinal material origin places which are clearly recorded in medical books, and the growth requirements of good medicinal materials can be met only by the geographical environment, water and soil, climate, sunshine and biological distribution; the selected medicinal materials are wild as much as possible according to natural growth requirements, and if the wild medicinal materials cannot meet the quantity requirements, the selected cultivated medicinal materials also grow naturally but cannot be used for promoting the growth of chemical fertilizers and pesticides; the requirement of sufficient-year picking is that the medicine standard is required to be met, namely the best service life recorded in medical books is met, and the picking can be carried out; following the rules of law, the time and mode of picking must be recorded according to the ancient law in order to avoid affecting the efficacy of the drug.

In the present invention, the adjuvant may include honey, preferably refined honey. The honey has the effects of seasoning, moistening, tonifying and the like, and also has certain functions of moderation and corrosion prevention; the honey is prepared into refined honey through a specific process, and the refined honey has the effects of dispelling the bias of drug properties to neutralize the honey, and removing water and impurities in the honey, so that the product is superior in quality, good in quality and durable in storage.

In the present invention, the preparation method of the refined honey may include: heating Mel to completely melt, removing froth when boiling, adding 5-15% cold water when turning into large bubbles and having a color of old red, further heating to boil, pouring out when it is hot, and filtering to obtain refined Mel. The refined honey prepared by the method has appropriate aging and tenderness degree, has sufficient viscosity, and can be fully fused with the medicinal juice.

In addition, optionally, the auxiliary material may further include at least one of brown sugar and yellow wine, and may be added according to actual needs.

In the invention, the mass ratio of the concentrated solution to the auxiliary materials can be 1: (0.9-1.1), preferably 1: 1.

in the invention, the raw materials and auxiliary materials meet the following requirements: the sun-dried ginseng artificially planted in 4-5 years meets the relevant regulations of DBS 22/024; rhizoma Polygonati, rhizoma Polygonati Odorati, fructus Citri Sarcodactylis, and rhizoma Dioscoreae meet the related regulations of pharmacopoeia of the people's republic of China (2010 version); the Chinese dates conform to the relevant regulations of GB/T5835; the honey conforms to the relevant regulations of GB 14963; the process water meets the relevant regulations of GB 5749.

In the present invention, the specific gravity of the concentrated solution is 1.1 to 1.3, preferably 1.2. In the process of concentrating the medicinal juice, if the medicinal juice is collected when the water content is too much, the medicinal juice cannot be prepared into paste, the concentration is not enough, the medicinal effect is low, and the medicinal juice is easy to deteriorate and cannot be stored; when the fire is too hot, the taste may be changed and the nature of the drug may be changed.

The ginseng and rhizoma polygonati cream has the soluble solid content of 63-80 percent; the content of total ginsenoside is more than or equal to 0.3%; has the effects of supplementing qi, nourishing yin, tonifying deficiency of viscera and the like.

The invention also provides a preparation method of the ginseng and rhizoma polygonati cream, which comprises the following steps:

A) preparing raw materials in parts by weight;

B) adding water into each raw material respectively for soaking until each raw material is soaked;

C) mixing the soaked materials, decocting, and filtering to obtain medicinal liquid;

D) concentrating the medicinal liquid to obtain concentrated solution;

E) mixing the concentrated solution and auxiliary materials according to the parts by weight, and collecting the paste to obtain the ginseng and rhizoma polygonati paste.

In the step A), after the raw materials are prepared, the raw materials can be rinsed by clean water to remove dust and impurities in the raw materials as required.

In the step B), the container for soaking the Chinese herbal medicines is preferably a barrel or a pot made of ceramic, copper, stainless steel and the like, and an iron container is not used; before soaking, adding appropriate amount of water to soak the medicinal materials, making them fully absorb swelling, and soaking later; when soaking, the raw materials can be soaked respectively, the water adding amount can be controlled to be 10-20cm higher than the water surface, the soaking time is not less than 4h, and the soaking time can be 24h, for example, based on the soaking of the raw materials.

In the step C), a purple copper pot, a stainless steel pot or a marmite can be adopted for decoction, an iron pot is forbidden, and a small-sized decoction machine can be selected; the decocting may be carried out at least three times; boiling with strong fire, decocting with slow fire for at least 1 hr, decocting with slow fire for 2-4 hr, and filtering to obtain decoction; mixing the obtained decoctions, standing for at least 6 hr, and filtering. The decoction mode of the first decoction of the root and bone seeds, the second decoction of the stem and fruit branches and the third decoction of the leaves and flowers can ensure that the drug effect of the root and bone seeds is completely extracted and the drug effect of the leaves and the flowers is not flying.

Preferably, the ginseng and the Chinese date can be decocted independently in the same way as other raw materials; the decoction obtained by decoction can be added together when the paste is collected, so that the effect and the efficacy can be fully exerted. The practice proves that the ginseng is decocted, extracted and concentrated separately, and then added when the paste is collected, so that the ginseng has better efficacy; the Chinese dates are traditional Chinese medicine raw materials which are high in sugar content and easy to separate out, the Chinese dates are high in proportion in the formula, the Chinese dates are prone to being separated out more in the decocting and extracting process, the concentration of decoction is increased, and the efficiency of separation of other traditional Chinese medicine materials is affected, so that in practice, the Chinese dates are decocted independently and added during concentration, and the extraction rate of active ingredients of other traditional Chinese medicine materials can be guaranteed.

Step D) may comprise: heating the medicinal liquid to boil, decocting with slow fire, and stirring to obtain concentrated solution; wherein, the stirring rod for stirring is preferably made of bamboo chips or a copper spoon, and the size of the bamboo chips or the copper spoon is adapted to the size of the pot. The invention controls the specific gravity of the concentrated solution to be 1.1-1.3; at the moment, a wooden stick is inserted into the concentrated solution and stirred, the wooden stick can be thinly wrapped by the medicinal liquid after being taken out, and the medicinal liquid drops are not scattered on paper and have a certain degree of formation; the concentrated solution with the specific gravity has good paste forming property, high drug effect, difficult deterioration and long storage time.

In the step E), the paste collection comprises the following steps: adding adjuvants into the concentrated solution, decocting with slow fire and stirring until the concentrated solution is "flag-hanging" or "dripping water into bead"; at this time, the decoction can be added, stirred sufficiently, extinguished and stopped to obtain the soft extract.

Further, the soft extract can be subpackaged and cooled; wherein, the split charging can be carried out by placing the soft extract to about 80 ℃ and quickly pouring the soft extract into a finished product container which is cleaned and disinfected in advance, wherein the finished product container is preferably a wide-mouth ceramic jar, a glass bottle or a food grade plastic jar bag and the like, and can also be filled into a vacuum plastic packaging bag by an automatic split charging machine; and putting the subpackaged paste prescription finished product into a purified paste cooling area for cooling, sealing after completely cooling to room temperature, and sending to a cold storage area for later use.

When the paste cooling and packaging operations are carried out, the indoor temperature is preferably controlled below the normal temperature, the humidity is preferably controlled to be 45-65%, and the configuration of an ultraviolet disinfection lamp can be properly added; the cold storage area for storing and distributing the packaged paste product can control the indoor temperature below the normal temperature, the humidity is preferably controlled to be 45-65%, and an ultraviolet disinfection lamp can be properly configured.

The implementation of the invention has at least the following advantages:

1. the ginseng and rhizoma polygonati cream disclosed by the invention is selected according to the requirement of four-hour conditioning, has universality in application, and is capable of tonifying qi, nourishing yin and tonifying deficiency of viscera;

2. the ginseng and polygonatum sibiricum paste disclosed by the invention is high in material selection standard, scientific and rigorous in boiling process, good in paste forming property, high in drug effect, not easy to deteriorate and long in storage time, and the drug effects of all the raw materials can be completely extracted.

Detailed Description

It should be noted that the following detailed description is exemplary and is intended to provide further explanation of the disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms also include the plural forms unless the context clearly dictates otherwise, and further, it is understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of the stated features, steps, operations, devices, components, and/or combinations thereof.

The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The raw material requirements for each example are as follows:

4-5 years of artificial planting of sun-dried ginseng: compliance with DBS22/024 related regulations;

rhizoma polygonati, radix polygonati officinalis, fingered citron and Chinese yam: meets the related regulation of the first part of pharmacopoeia of the people's republic of China 2010 edition;

chinese date: the relevant regulation of GB/T5835 is met;

honey: compliance with relevant regulations of GB 14963;

production and processing water: in compliance with the relevant provisions of GB 5749.

Example 1

1. Stock preparation

Preparing the following materials in parts by weight:

150 parts of sun-dried ginseng, 300 parts of rhizoma polygonati, 80 parts of polygonatum odoratum, 150 parts of fingered citron, 120 parts of Chinese yam and 200 parts of Chinese date are artificially planted in 4-5 years.

2. Rinsing

Rinsing the raw materials with clear water to remove dust and impurities in the raw materials.

3. Soaking

Putting the rinsed raw materials into a clean casserole with the same volume, adding a proper amount of water to soak the medicinal materials, and fully absorbing and swelling the medicinal materials.

Later, water is added until the height is about 10 cm higher than the medicine surface, and the medicine is soaked for 24 hours, so that all the raw materials are fully soaked.

4. Decocting and decocting

Decocting the soaked materials except Ginseng radix and fructus Jujubae with fire; boiling with strong fire, then boiling with slow fire for about 1 hr, boiling with slow fire for about 3 hr, and filtering with gauze to obtain first decoction; adding clear water to soak the original medicine residues, and then decocting with fire, wherein the decoction method is as above, and the decoction is a second decoction; when the third decoction is carried out, the smell is thin, and the decoction is completely filtered, namely the decoction dregs are poured away (if the decoction is still thick, the decoction can be further decocted for 1 time); mixing the decoctions, standing, precipitating, and filtering to obtain medicinal liquid.

Meanwhile, the ginseng and the Chinese date are decocted separately in the above way to obtain ginseng medicinal juice and Chinese date medicinal juice respectively.

5. Concentrating

Pouring the filtered medicinal liquid into a pot for concentration, decocting with strong fire, accelerating water evaporation, removing floating foam at any time, slowly making the medicinal liquid become thick, further concentrating with slow fire, stirring continuously, introducing a wooden stick similar to a chopstick into the medicinal liquid, stirring, taking out, and determining whether the medicinal liquid can wrap the wooden stick with a thin layer; if the medicinal juice can be dripped on paper, the medicinal juice does not spread and forms a proper degree, and then concentrated solution (namely clear paste) is prepared, and the specific gravity of the concentrated solution is about 1.2.

6. Refined honey

Heating Mel in a pot to completely melt, removing the floating foam with mesh screen or silk screen when boiling, boiling until most of water in Mel is evaporated, turning into big bubbles, adding about 10% cold water, heating to boil, pouring out when it is hot, filtering with silk screen, and removing impurities to obtain refined Mel.

7. Recovery cream

According to the mass ratio of 1: 1 pour into the clear paste with the honey refining, put slowly to decoct on the small fire, constantly stir with the shovel, ladle out the juice with the ladle and up to raise and splash the aqueous vapor condition in the cream, have aqueous vapor then continue to decoct if vaporific too much, can ladle out the juice with the ladle at this moment and pour slowly at intervals, draw the pot in and constantly from the ladle border as the juice, be "draw the flag" form promptly.

After the paste juice is 'flag-pulled', the paste juice is dripped into clear water by a wooden stick and is condensed into beads without scattering, or is dripped on reed paper, such as dark pearls, and is individually formed, moistened without paralysis, slightly shaken without water stain marks, namely, the paste juice is 'dripping into beads', and the ginseng medicinal juice and the Chinese date medicinal juice which are separately decocted are timely added, fully stirred, extinguished and stopped boiling, so that the paste is prepared.

8. Subpackaging, cooling, storing

Placing the soft extract at about 80 deg.C, quickly pouring into cleaned and sterilized container, and packaging.

And (4) placing the subpackaged paste prescription finished product in a purified paste cooling area for cooling, sealing after completely cooling to room temperature, and sending to a cold storage area for later use.

Example 2

1. Stock preparation

Preparing the following materials in parts by weight:

145 parts of sun-dried ginseng, 310 parts of rhizoma polygonati, 85 parts of polygonatum odoratum, 140 parts of fingered citron, 125 parts of Chinese yam and 190 parts of Chinese date are artificially planted in 4-5 years.

2. Rinsing

3. Soaking

And later, adding water until the water level is about 15 cm higher than the medicine surface, and soaking for 24 hours to fully soak the raw materials.

4. Decocting and decocting

Decocting the soaked materials except Ginseng radix and fructus Jujubae with fire; boiling with strong fire, then boiling with slow fire for about 1 hr, boiling with slow fire for about 2 hr, and filtering with gauze to obtain first medicinal liquid; adding clear water to soak the original medicine residues, and then decocting with fire, wherein the decoction method is as above, and the decoction is a second decoction; when the third decoction is carried out, the smell is thin, and the decoction is completely filtered, namely the decoction dregs are poured away (if the decoction is still thick, the decoction can be further decocted for 1 time); mixing the decoctions, standing, precipitating, and filtering to obtain medicinal liquid.

Meanwhile, ginseng and Chinese date are decocted separately in the following mode to obtain ginseng medicinal juice and Chinese date medicinal juice respectively.

5. Concentrating

Pouring the filtered medicine juice into a pot for concentration, decocting with strong fire, accelerating water evaporation, removing floating foam at any time, slowly changing the medicine juice into thick liquid, further concentrating with slow fire, stirring continuously, introducing a wooden stick similar to a chopstick into the medicine soup for stirring, taking out the medicine soup, and judging whether the wooden stick can be wrapped by a thin layer; if the medicinal juice can be dripped on paper, the medicinal juice does not spread and forms a proper degree, and then concentrated solution (namely clear paste) is prepared, and the specific gravity of the concentrated solution is about 1.1.

6. Refined honey

7. Recovery cream

According to the mass ratio of 1: 0.9 pour into the clear paste with the honey, put slowly to decoct on the small fire, constantly stir with the shovel, scoop out the juice with the ladle and up to raise and splash the aqueous vapor condition in the cream, have aqueous vapor if vaporific too much then continue to decoct, can scoop out the juice with the ladle at this moment and pour slowly, draw the pot and constantly from the ladle border when the juice, be "draw the flag" form promptly.

8. Subpackaging, cooling, storing

Example 3

1. Stock preparation

Preparing the following materials in parts by weight:

155 parts of sun-dried ginseng, 290 parts of rhizoma polygonati, 75 parts of polygonatum odoratum, 160 parts of fingered citron, 115 parts of Chinese yam and 210 parts of Chinese date are artificially planted in 4-5 years.

2. Rinsing

3. Soaking

Later, water is added until the height is about 10 cm higher than the medicine surface, and the medicine is soaked for 20 hours, so that all the raw materials are fully soaked.

4. Decocting and decocting

Decocting the soaked materials with fire (decocting Ginseng radix and fructus Jujubae and other materials simultaneously); boiling with strong fire, then boiling with slow fire for about 1 hr, boiling with slow fire for about 4 hr, and filtering with gauze to obtain first decoction; adding clear water to soak the original medicine residues, and then decocting with fire, wherein the decoction method is as above, and the decoction is a second decoction; when the third decoction is carried out, the smell is thin, and the decoction is completely filtered, namely the decoction dregs are poured away (if the decoction is still thick, the decoction can be further decocted for 1 time); mixing the decoctions, standing, precipitating, and filtering to obtain medicinal liquid.

5. Concentrating

Pouring the filtered medicine juice into a pot for concentration, decocting with strong fire, accelerating water evaporation, removing floating foam at any time, slowly changing the medicine juice into thick liquid, further concentrating with slow fire, stirring continuously, introducing a wooden stick similar to a chopstick into the medicine soup for stirring, taking out the medicine soup, and judging whether the wooden stick can be wrapped by a thin layer; if the medicinal juice can be dripped on paper, the medicinal juice does not spread and forms a proper degree, and then concentrated solution (namely clear paste) is prepared, and the specific gravity of the concentrated solution is about 1.3.

6. Refined honey

7. Recovery cream

According to the mass ratio of 1: 1.1 pour into the clear paste with the honey refining, put slowly to decoct on the small fire, constantly stir with the shovel, scoop out the juice with the ladle and up to raise and splash the aqueous vapor condition in the cream, have aqueous vapor if vaporific too much then continue to decoct, can scoop out the juice with the ladle at this moment and pour slowly, pull the pot in and constantly from the ladle border as the juice, be "pull the flag" form promptly.

8. Subpackaging, cooling, storing

Test example 1

The new ginseng and rhizoma polygonati cream prepared in the example 1 (tested immediately after preparation and not refrigerated) is subjected to quality detection, and the results are shown in tables 1 to 5.

TABLE 1 sensory indices

TABLE 2 physical and chemical indexes

Item	Index (I)	Inspection method
			Soluble solids (20 ℃, refractometer method)%	63-80	GB/T 12143
Total ginsenoside content ≧	0.3	NY 318

TABLE 3 pollutant limits

Item	Index (I)	Inspection method
			Lead (in terms of Pb), mg/kg	≤0.29	GB 5009.12

TABLE 4 microbial limits

TABLE 5 nutrient composition Table

Item	Each 100 g	NRV％
			(Energy)	1290 KJ	15％
Protein	1.2 g	2％
			Fat	2.7 g	5％
Carbohydrate compound	68.8 g	23％
			Sodium salt	14 mg of	1％

Test example 2

The ginseng and rhizoma polygonati cream prepared in example 1 was stored in a cold storage area for three years, and then taken out for quality inspection according to the method of test example 1.

The results show that: the quality difference between the product of the ginseng sealwort cream after being stored for three years and the newly prepared ginseng sealwort cream is less than or equal to 3 percent, thereby showing that: the ginseng and rhizoma polygonati paste product prepared by the preparation method has long storage time and stable product quality.

Comparative example 1

The process is substantially the same as example 1 except that the honey refining step is not performed, and honey is directly poured into the clear paste for paste collection.

Referring to the method of test example 1, the newly prepared ginseng radix polygonati cream of this control example 1 and the ginseng radix polygonati cream stored in a cold storage area for three months were subjected to quality inspection, and the results showed that: after the ginseng radix polygonati cream of the comparison example is stored for 3 months, the difference between the quality of the product and the quality of a newly prepared ginseng radix polygonati cream is more than or equal to 20 percent, thereby showing that: the ginseng and rhizoma polygonati cream prepared in the comparison example has poor cream forming performance, short preservation time and poor product quality.

Test example 3

The ginseng and rhizoma polygonati cream prepared in the examples 1 to 3 and the comparative example 1 is applied to the patients with deficiency symptoms respectively, and the ginseng and rhizoma polygonati cream is taken once in the morning and at night, 15g (about 1 spoon) each time, and is continuously taken for 7 days (namely one treatment course).

The criteria for diagnosis and evaluation of efficacy are as follows:

diagnostic criteria: has the symptoms of pale face and lips, listlessness, palpitation, short breath, spontaneous perspiration, night sweat, diarrhea, frequent micturition, tender tongue without fur, weak pulse, etc.;

the effect is shown: more than 70% of symptoms are eliminated;

the method has the following advantages: more than 30% and less than 70% of symptoms are eliminated;

and (4) invalidation: the symptom is eliminated by less than 30 percent.

The therapeutic effect of each ginseng and rhizoma polygonati cream is shown in table 6.

TABLE 6 therapeutic effect of Ginseng radix and rhizoma Polygonati extract

As can be seen from the results of table 6:

the ginseng and rhizoma polygonati cream prepared by the embodiments of the invention has high significant efficiency in treating deficiency, particularly has significant efficiency of more than 97 percent when the ginseng and the Chinese date are decocted independently, which indicates that the mode is particularly beneficial to the extraction and the effect exertion of effective components in the raw materials; in addition, compared with the comparative example 1, the honey is prepared into the refined honey through a specific process, so that bias of drug properties can be effectively eliminated, neutralization is realized, and the quality and curative effect of the product are greatly improved. The ginseng and sealwort ointment disclosed by the invention has the advantages of good ointment forming property, high drug effect, difficulty in deterioration, long storage time and the like, and can tonify qi, drive yin and tonify various deficiency of internal organs.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. The ginseng and rhizoma polygonati cream is characterized by comprising a concentrated solution and auxiliary materials, wherein the concentrated solution is prepared by decocting raw materials in water and concentrating, and the raw materials comprise the following components in parts by weight: 155 portions of sun-dried ginseng 145-containing materials, 310 portions of sealwort 290-containing materials, 75-85 portions of polygonatum odoratum, 160 portions of fingered citron 140-containing materials, 125 portions of Chinese yam 115-containing materials and 210 portions of Chinese date 190-containing materials are artificially planted for 4-5 years.

2. The ginseng radix polygonati cream according to claim 1, wherein the auxiliary materials comprise honey, preferably refined honey, and optionally at least one of brown sugar and yellow wine;

preferably, the preparation method of the refined honey comprises the following steps: heating Mel to completely melt, removing froth when boiling, adding 5-15% cold water when turning into large bubbles and having a color of old red, further heating to boil, pouring out when it is hot, and filtering to obtain refined Mel.

3. The ginseng radix polygonati cream according to claim 1, wherein the specific gravity of the concentrated solution is 1.1-1.3.

4. The ginseng radix polygonati cream according to claim 1, wherein the mass ratio of the concentrated solution to the auxiliary materials is 1: (0.9-1.1).

5. The ginseng radix polygonati cream according to claim 1, wherein the content of soluble solids is 63-80%; the content of total ginsenoside is not less than 0.3%.

6. The method for preparing ginseng radix polygonati cream according to any one of claims 1 to 5, comprising the steps of:

A) preparing raw materials in parts by weight;

D) concentrating the medicinal liquid to obtain concentrated solution;

7. The preparation method according to claim 6, wherein in the step B), water is added during soaking until the water level is 10-20cm higher than that of the raw material, and the soaking time is not less than 4h, preferably 24 h.

8. The method according to claim 6, wherein in step C), the decoction is carried out at least three times; boiling with strong fire, decocting with slow fire for at least 1 hr, decocting with slow fire for 2-4 hr, and filtering to obtain decoction; mixing the medicinal juices, standing for at least 6 hr, and filtering;

preferably, the ginseng and the Chinese date are decocted separately, and the decoction obtained by decoction is added when the paste is collected.

9. The method of claim 6, wherein step D) comprises: heating the medicinal liquid to boil, decocting with slow fire, and stirring to obtain concentrated solution.

10. The preparation method according to claim 6, wherein in the step E), the paste collection comprises: adding adjuvants into the concentrated solution, decocting with slow fire, and stirring until the concentrated solution is "flag-hanging" or "dripping water and beading".