CN106377599A - Trollflower chewing gum and preparation method thereof - Google Patents
Trollflower chewing gum and preparation method thereof Download PDFInfo
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- CN106377599A CN106377599A CN201611062665.0A CN201611062665A CN106377599A CN 106377599 A CN106377599 A CN 106377599A CN 201611062665 A CN201611062665 A CN 201611062665A CN 106377599 A CN106377599 A CN 106377599A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The invention belongs to the technical field of traditional Chinese medicine chewing gums and particularly relates to a trollflower chewing gum and a preparation method thereof. The trollflower chewing gum is prepared from the following main raw materials in parts by weight: 120-140 parts of edible gum base, 6-10 parts of lecithin, 10-15 parts of glycerinum, 14-20 parts of xylitol, 30-40 parts of trollflower, 5-9 parts of lotus leaf, 10-14 parts of folium eriobotryae, 7-10 parts of radix glycyrrhizae, 5-9 parts of fructus gardeniae, 8-12 parts of radix puerariae, 4-8 parts of herba menthae, 6-9 parts of radix platycodi, 3-6 parts of herba portulacae, 5-9 parts of folium perillae, 3-5 parts of fructus citri sarcodactylis and 3-5 parts of isomaltitol. The trollflower chewing gum is safe, and is mild in medicine property, free of irritation and convenient to carry; clinical application proves that the trollflower chewing gum has the effects of obviously improving the main symptoms such as dry cough, throat itching and pharyngalgia and the like of patients with chronic pharyngitis and obviously improving the symptoms such as retropharyneal folliculosis, excreta and throat congestion and the like.
Description
Technical field
The invention belongs to Chinese medicine chewing gum technical field is and in particular to a kind of trollflower chewing gum and preparation method thereof.
Background technology
Chronic pharyngitis is pharynx mucous membrane, under mucous membrane and adenoid chronic inflammation.Chronic pharyngitis is more common in adult, children
Also may occur in which.Constitutional symptom is all inconspicuous, based on local symptom.Various chronic pharyngitis symptom is substantially similar and varied,
Be difficult to bring up as pharyngeal sense of discomfort, foreign body sensation, pharyngeal secretion, pharyngeal gargalesthesia, burn feeling, dry sensation or excitement, also can have
Hypodynia sense.Because pharynx rear wall is generally because pharyngeal chronic inflammation causes compared with thick secretions adhesion, and due to nose, nasal sinus, nasopharynx
Portion's pathology causes night mouth breathing, irritable cough and nausea when Chang Chen rises.Because foreign body in pharynx sense can behave as
Frequently swallow.Pharyngeal secretion is few and is difficult expectoration person and often shows as habitually dry cough and action of coughing up phlegm of clearing one's throat, if firmly
Cough or clear one's throat and can cause pharyngeal mucosa hemorrhage, cause to carry blood in secretion.
Chinese patent application 201210235845.X discloses a kind of Chinese medicine chewing gum, and this invention is by Feng Dan, peppermint, the leaves of pulse plants
The concentrate that fragrant, four kinds of Chinese medicines of green tea process and the basic ingredient of the composition chewing gum such as Arabic gum, glue nurse base are made.
Chinese patent application 201210140796.1 discloses a kind of chewing gum treating chronic pharyngitis, and it is by glue system
Agent, emulsifying agent, glycerine and Chinese medicine proportioning form, and the optimum ratio by weight of the Chinese medicine in its chewing gum is：8 parts of radix polygonati officinalis, profound
13 parts of ginseng, 15 parts of the tuber of dwarf lilyturf, 11 parts of radix rehmanniae recen, 13 parts of balloonflower root, 10 parts of Rhizoma Sparganii, 14 parts of moutan bark, 10 parts of the radix paeoniae rubrathe, 8 parts of cicada slough, peppermint
10 parts, 13 parts of dried orange peel, 7 parts of Radix Glycyrrhizae, 7 parts of glue preparation, 8 parts of emulsifying agent, 5 parts of glycerine.
Chinese patent application 201410477225.6 discloses a kind of Chinese medicine odor type chewing gum, raw materials used in contain Buddha's warrior attendant
Rattan 3-5 part, Chinese mugwort 5-8 part, Momordica grosvenori 2-4 part, root of large-flowered skullcap 2-4 part, Radix Isatidis 2-4 part, honeycomb 7-11 part, Herba Andrographitis 7-11 part,
Peppermint 3-5 part, ambergris 1-3 part, rosemary 1-3 part.
The leisure product that chewing gum is liked as people, are accepted by increasing people.But, traditional at present chewing gum
Mainly it is made by edible glue and essence, can be ptyalized by chewing, promote digestion, simultaneously cleaning tooth and sky
The bacterium in chamber, but long-term chewing, essence therein and noxious material can reach throat, result in blockage, and throat is caused hinder
Evil, and the chewing gum product for patients with chronic pharyngitis is less, and effect is undesirable.So, develop that a kind of effect is good, be directed to
The chewing gum of patients with chronic pharyngitis is necessary.
Content of the invention
For the deficiencies in the prior art, it is an object of the invention to provide a kind of trollflower chewing gum.Lily feet fancy top of the present invention
Fragrant sugar safety, the property of medicine are gentle, and non-stimulated, it is very convenient to take and carry.Confirm through clinical, to patients with chronic pharyngitis dry cough, pharynx
Itch, the cardinal symptom such as pharyngalgia improves significantly and confirms through clinical, to pharynx rear wall FH, secretion, congestion of throat
Obvious etc. the improvement result of sign.
A kind of trollflower chewing gum, is prepared from by the primary raw material of following weight parts：
Edible matrix 120-140 part, lecithin 6-10 part, glycerine 10-15 part, xylitol 14-20 part, trollflower 30-40
Part, lotus leaf 5-9 part, loguat leaf 10-14 part, Radix Glycyrrhizae 7-10 part, cape jasmine 5-9 part, root of kudzu vine 8-12 part, peppermint 4-8 part, balloonflower root 6-9
Part, purslane 3-6 part, perilla leaf 5-9 part, Buddha's hand 3-5 part and hydroxyl isomaltulose 3-5 part.
A kind of trollflower chewing gum, preferred scheme is to be prepared from by the primary raw material of following weight parts：
128 parts of edible matrix, 8 parts of lecithin, 13 parts of glycerine, 18 parts of xylitol, 33 parts of trollflower, 7 parts of lotus leaf, loguat leaf
11 parts, 8 parts of Radix Glycyrrhizae, 7 parts of cape jasmine, 9 parts of the root of kudzu vine, 6 parts of peppermint, 7 parts of balloonflower root, 4 parts of purslane, 7 parts of perilla leaf, 4 parts of Buddha's hand and different
4 parts of maltitol.
The preparation method of described trollflower chewing gum is：
S1 takes trollflower, is ground into meal, sieves, and adds ethanol, the volume fraction of ethanol is 50%～75%, ethanol
Weight is 12～15 times of above-mentioned trollflower meal weight, extracts at 65～75 DEG C, extracts three times, extracts 1.5 hours every time,
Merge No. three extracts, be condensed into the thick paste that relative density is 1.32～1.36；
Lotus leaf, loguat leaf, Radix Glycyrrhizae, cape jasmine, balloonflower root, purslane, perilla leaf and Buddha's hand are cleaned by S2, are placed in extractor,
The decocting adding 9～13 times of above-mentioned 8 kinds of raw materials boils three times, decocts 2 hours for the first time, and second and third time decoct 1 hour, filter
Cross, merging filtrate, being evaporated to relative density is 1.15～1.22, plus 95% ethanol, make alcohol content reach 65%, stirring is all
Even, stand 24 hours, take supernatant liquor, decompression recycling ethanol, be condensed into the thick paste that relative density is 1.33～1.37；
S3 takes the root of kudzu vine, is ground into meal, crosses 50 mesh sieves, takes peppermint, is ground into meal, crosses 70 mesh sieves, will be thick for the above-mentioned root of kudzu vine
Powder and the mixing of peppermint meal, add ethanol, the volume fraction of ethanol is 60%～80%, and the weight of ethanol is above-mentioned root of kudzu vine meal
With 10～14 times of peppermint meal gross weight, extract at 60～75 DEG C, extract twice, extract 2 hours for the first time, carry for the second time
Take 1 hour, merge extract twice, be condensed into the thick paste that relative density is 1.34～1.40；
Step S1 gained thick paste, step S2 gained thick paste and step S3 gained thick paste are mixed by S4；
Edible matrix is placed in dry in 55～65 DEG C of baking oven and softens by S5, and the edible matrix after softening is put into mixer
Interior stirring, sequentially adds step S4 gained, xylitol, hydroxyl isomaltulose, glycerine, lecithin stir in mixer, pressure
Sheetmolding, obtains final product.
Preferably, the volume fraction of described step S1 ethanol is 65%.
Preferably, the weight of described step S1 ethanol is 14 times of above-mentioned trollflower meal weight.
Preferably, described step S1 is extracted at 70 DEG C.
Preferably, step S1 described in described step S1 is condensed into the thick paste that relative density is 1.35.
Preferably, described step S2 adds the decocting of 11 times of above-mentioned 8 kinds of raw materials to boil three times.
Preferably, described step S2 is evaporated to relative density is 1.18.
Preferably, described step S2 is condensed into the thick paste that relative density is 1.35.
Preferably, the volume fraction of described step S3 ethanol is 75%.
Preferably, the weight of described step S3 ethanol is 13 times of above-mentioned root of kudzu vine meal and peppermint meal gross weight.
Preferably, described step S3 is extracted at 70 DEG C.
Preferably, described step S3 is condensed into the thick paste that relative density is 1.35.
Preferably, edible matrix is placed in dry in 60 DEG C of baking oven and softens by described step S5.
The effect of primary raw material used by the present invention：
Trollflower：Ji Yuan：For ranunculaceae plant trollflower and party's lobe trollflower, short trollflower, Trollius ledebouri flower.Property
Taste：Bitter；Cold nature.Return lung；Stomach.Indication：Clearing heat and detoxicating；Detumescence；Improving eyesight.Cure mainly cold, fever；Abscess of throat；Mouthful
Sore；Swelling and aching of gum；Bleeding gums；Red eye, swell pain；Furuncle swelling toxin；Acute myringitis；Acute lymphangitis.
Lotus leaf：Base：Dried leaf for nymphaeaceae plant lotus.The property of medicine：Hardship, puts down.Return liver, spleen, stomach.Function cures mainly：Clearly
Pyrolysis heat, sending up the lucid yang, cooling blood and hemostasis.For multiple haemorrhages and postpartum anemic fainting.
Loguat leaf：Base：Leaf for rosaceous plant loquat.The property of medicine：Bitter, pungent；Cold；Nontoxic.Return lung, the heart, stomach.Function
Cure mainly：Removing heat from the lung to relieve cough, harmonizing stomach and lowering adverse Qi, quench the thirst.Main lung feverish cough, deficiency of Yin labor is coughed, hemoptysis, bleeding from five sense organs or subcutaneous tissue, stomach energy is vomitted the sound of vomiting.
Radix Glycyrrhizae：Base：Root and rhizome is dried for glycyrrhizic legume, swollen fruit Radix or glycyrrhiza glabra.The property of medicine：Sweet, put down.
The thoughts of returning home, lung, spleen, stomach.Function cures mainly：Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For spleen
Stomach is weak, lassitude hypodynamia, palpitation, coughing with a lot of sputum, institute's abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviates drug toxicity, strong
Property.
Cape jasmine：Base：For the dry mature fruit of madder wort cape jasmine, its root also can be used as medicine.The property of medicine：Hardship, trembles with fear.Return
The heart, lung, tri-jiao channel.Indication：Fruit：Purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body.For Vexed, jaundice urine is red,
Blood strangury and dry pain, blood-head tells nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles；Control outward bruise pain.Root：Purging intense heat and detonicating, clearing heat and promoting diuresis, cool blood dissipates
The stasis of blood.For catarrhal jaundice, traumatic injury, acute toothache.
The root of kudzu vine：Base：Dry root for legume pueraria lobata.The property of medicine：Sweet, pungent, cool.Returns spleen, stomach.Function cures mainly：Solution
Flesh is brought down a fever, and promotes the production of body fluid, promoting eruption, Shengyang Zhixie.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hot dysentery,
Have loose bowels, hypertension neck pain.
Peppermint：Base：Dry aerial parts for Labiatae mint peppermint.The property of medicine：Pungent, cool.Return lung, Liver Channel.
Function cures mainly：Dispelling wind-heat.Refresh oneself, promoting eruption.For anemopyretic cold, wind-warm syndrome from the beginning of, headache, hot eyes, larynx numbness, aphtha, rubella,
Measles, Breast bilges frowsty about.
Balloonflower root：Base：Root for Campanulaceae balloonflower root.The property of medicine：Bitter, pungent, put down.Return lung warp.Function cures mainly：A surname's lung, profit
Pharynx, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, sound is mute, lung carbuncle pyemesis, and sore purulence becomes not burst.
Purslane：Base：Herb for portulacaceous plant purslane.Chemical composition of Chinese materia medica：Herb contains and removes first kidney in a large number
Upper parathyrine and volume sylvite (including potassium nitrate, potassium chloride, potassium sulfate and other sylvite).Also containing DOPA, dopamine, betanidin,
Isobetanidin, different beet glucoside, oxalic acid, malic acid, citric acid, glutamic acid, aspartic acid, alanine and glucose, fructose, sugarcane
Sugar etc..And contain substantial amounts of poly- omega-3 unsaturated fatty acid.The property of medicine：Acid, trembles with fear.Return large intestine, Liver Channel.Function cures mainly：Clearing heat and detoxicating, cool
Blood stops blooding.For toxic-heat and blood stasis, carbuncle swells furunculosis, eczema, erysipelas, snake bite and insect sting, have blood in stool, hemorrhoid blood, metrostaxis.
Perilla leaf：Base：Leaf for labiate purple perilla and wild purple perilla or browse.The property of medicine：Taste is pungent；Warm in nature.Return lung,
Spleen, stomach.Function cures mainly：Expelling cold and relieving exterior syndrome, ventilatings the lung and resolving phlegm, promoting the circulation of qi and in, antiabortive, cowfish crab poison.Main exterior syndrome due to wind-cold, phlegm of coughing
Many, crisp turgor, n and V, stomachache is vomited and diarrhoea, and nausea is got along well, and gestation evil is cloudy, eats fish and crab poisoning.
Buddha's hand：Base：This product is the dry fruit of Rutaceae citrus plant Buddha's hand.The property of medicine：Pungent, bitter, sour, temperature.Return liver,
Spleen, lung channel.Function cures mainly：Liver-smoothing, qi-regulating, and stomach and alleviating pain.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food is vomitted.
Gained trollflower chewing gum of the present invention is with trollflower, lotus leaf, loguat leaf and Radix Glycyrrhizae etc. as raw material, takes through science
Join, be prepared from, taking convenience.
Compared with prior art, the trollflower chewing gum that the present invention provides has the advantage that：
(1) trollflower chewing gum safety of the present invention, the property of medicine are gentle, non-stimulated；
(2) take and carry very convenient；
(3) each raw material interphase interaction used in trollflower chewing gum of the present invention, has clearing heat and detoxicating, removing heat from the lung to relieve cough, dispels
Phlegm and relieving cough, throat-clearing throat-moistening, ventilating the lung and resolving phlegm, swelling and pain relieving the effects such as, confirm through clinical, trollflower chewing gum of the present invention is to chronic pharynx
Scorching patient's dry cough, pharynx are itched, the cardinal symptom such as pharyngalgia improves significantly, and to pharynx rear wall FH, secretion, pharyngeal fill
The improvement result of the signs such as blood is obvious.
Specific embodiment
Below by way of the description of specific embodiment, the invention will be further described, but this is not the limit to the present invention
System, according to the basic thought of the present invention, various modifications may be made or improves for those skilled in the art, but without departing from this
The basic thought of invention, all within the scope of the present invention.
A kind of trollflower chewing gum of embodiment 1
Trollflower chewing gum is prepared from (every part is 800g) by the primary raw material of following weight parts：
120 parts of edible matrix, 6 parts of lecithin, 10 parts of glycerine, 14 parts of xylitol, 30 parts of trollflower, 5 parts of lotus leaf, loguat leaf
10 parts, 7 parts of Radix Glycyrrhizae, 5 parts of cape jasmine, 8 parts of the root of kudzu vine, 4 parts of peppermint, 6 parts of balloonflower root, 3 parts of purslane, 5 parts of perilla leaf, 3 parts of Buddha's hand and different
3 parts of maltitol.
The preparation method of above-mentioned trollflower chewing gum is：
S1 takes trollflower, is ground into meal, sieves, and adds ethanol, the volume fraction of ethanol is 65%, and the weight of ethanol is
14 times of above-mentioned trollflower meal weight, extract at 70 DEG C, extract three times, extract 1.5 hours every time, merge three extractions
Liquid, is condensed into the thick paste that relative density is 1.35；
Lotus leaf, loguat leaf, Radix Glycyrrhizae, cape jasmine, balloonflower root, purslane, perilla leaf and Buddha's hand are cleaned by S2, are placed in extractor,
The decocting adding 9 times of above-mentioned 8 kinds of raw materials boils three times, decocts 2 hours for the first time, and second and third time decoct 1 hour, filtration,
Merging filtrate, being evaporated to relative density is 1.15, plus 95% ethanol, makes alcohol content reach 65%, stirs, stands 24
Hour, take supernatant liquor, decompression recycling ethanol, be condensed into the thick paste that relative density is 1.33；
S3 takes the root of kudzu vine, is ground into meal, crosses 50 mesh sieves, takes peppermint, is ground into meal, crosses 70 mesh sieves, will be thick for the above-mentioned root of kudzu vine
Powder and the mixing of peppermint meal, add ethanol, the volume fraction of ethanol is 60%, and the weight of ethanol is above-mentioned root of kudzu vine meal and peppermint
10 times of meal gross weight, extract at 60 DEG C, extract twice, extract 2 hours for the first time, extract 1 hour for second, merge two
Secondary extract, is condensed into the thick paste that relative density is 1.34；
Step S1 gained thick paste, step S2 gained thick paste and step S3 gained thick paste are mixed by S4；
Edible matrix is placed in dry in 55 DEG C of baking oven and softens by S5, the edible matrix after softening is put in mixer and stirs
Mix, sequentially add step S4 gained, xylitol, hydroxyl isomaltulose, glycerine, lecithin stir in mixer, compressing tablet becomes
Type, obtains final product.
A kind of trollflower chewing gum of embodiment 2
Trollflower chewing gum is prepared from (every part is 800g) by the primary raw material of following weight parts：
140 parts of edible matrix, 10 parts of lecithin, 15 parts of glycerine, 20 parts of xylitol, 40 parts of trollflower, 9 parts of lotus leaf, loquat
14 parts of leaf, 10 parts of Radix Glycyrrhizae, 9 parts of cape jasmine, 12 parts of the root of kudzu vine, 8 parts of peppermint, 9 parts of balloonflower root, 6 parts of purslane, 9 parts of perilla leaf, 5 parts of Buddha's hand
With 5 parts of hydroxyl isomaltulose.
The preparation method of above-mentioned trollflower chewing gum is：
S1 takes trollflower, is ground into meal, sieves, and adds ethanol, the volume fraction of ethanol is 75%, and the weight of ethanol is
15 times of above-mentioned trollflower meal weight, extract at 75 DEG C, extract three times, extract 1.5 hours every time, merge three extractions
Liquid, is condensed into the thick paste that relative density is 1.36；
Lotus leaf, loguat leaf, Radix Glycyrrhizae, cape jasmine, balloonflower root, purslane, perilla leaf and Buddha's hand are cleaned by S2, are placed in extractor,
The decocting adding 9 times of above-mentioned 8 kinds of raw materials boils three times, decocts 2 hours for the first time, and second and third time decoct 1 hour, filtration,
Merging filtrate, being evaporated to relative density is 1.15, plus 95% ethanol, makes alcohol content reach 65%, stirs, stands 24
Hour, take supernatant liquor, decompression recycling ethanol, be condensed into the thick paste that relative density is 1.33；
S3 takes the root of kudzu vine, is ground into meal, crosses 50 mesh sieves, takes peppermint, is ground into meal, crosses 70 mesh sieves, will be thick for the above-mentioned root of kudzu vine
Powder and the mixing of peppermint meal, add ethanol, the volume fraction of ethanol is 60%%, and the weight of ethanol is above-mentioned root of kudzu vine meal and thin
10 times of lotus meal gross weight, extract at 60 DEG C, extract twice, extract 2 hours for the first time, extract 1 hour for second, merge
Extract twice, is condensed into the thick paste that relative density is 1.34；
Step S1 gained thick paste, step S2 gained thick paste and step S3 gained thick paste are mixed by S4；
Edible matrix is placed in dry in 65 DEG C of baking oven and softens by S5, the edible matrix after softening is put in mixer and stirs
Mix, sequentially add step S4 gained, xylitol, hydroxyl isomaltulose, glycerine, lecithin stir in mixer, compressing tablet becomes
Type, obtains final product.
A kind of trollflower chewing gum of embodiment 3
Trollflower chewing gum is prepared from (every part is 800g) by the primary raw material of following weight parts：
128 parts of edible matrix, 8 parts of lecithin, 13 parts of glycerine, 18 parts of xylitol, 33 parts of trollflower, 7 parts of lotus leaf, loguat leaf
11 parts, 8 parts of Radix Glycyrrhizae, 7 parts of cape jasmine, 9 parts of the root of kudzu vine, 6 parts of peppermint, 7 parts of balloonflower root, 4 parts of purslane, 7 parts of perilla leaf, 4 parts of Buddha's hand and different
4 parts of maltitol.
The preparation method of above-mentioned trollflower chewing gum is：
S1 takes trollflower, is ground into meal, sieves, and adds ethanol, the volume fraction of ethanol is 65%, and the weight of ethanol is
14 times of above-mentioned trollflower meal weight, extract at 70 DEG C, extract three times, extract 1.5 hours every time, merge three extractions
Liquid, is condensed into the thick paste that relative density is 1.35；
Lotus leaf, loguat leaf, Radix Glycyrrhizae, cape jasmine, balloonflower root, purslane, perilla leaf and Buddha's hand are cleaned by S2, are placed in extractor,
The decocting adding 11 times of above-mentioned 8 kinds of raw materials boils three times, decocts 2 hours for the first time, and second and third time decoct 1 hour, filtration,
Merging filtrate, being evaporated to relative density is 1.18, plus 95% ethanol, makes alcohol content reach 65%, stirs, stands 24
Hour, take supernatant liquor, decompression recycling ethanol, be condensed into the thick paste that relative density is 1.35；
S3 takes the root of kudzu vine, is ground into meal, crosses 50 mesh sieves, takes peppermint, is ground into meal, crosses 70 mesh sieves, will be thick for the above-mentioned root of kudzu vine
Powder and the mixing of peppermint meal, add ethanol, the volume fraction of ethanol is 75%, and the weight of ethanol is above-mentioned root of kudzu vine meal and peppermint
13 times of meal gross weight, extract at 70 DEG C, extract twice, extract 2 hours for the first time, extract 1 hour for second, merge two
Secondary extract, is condensed into the thick paste that relative density is 1.35；
Step S1 gained thick paste, step S2 gained thick paste and step S3 gained thick paste are mixed by S4；
Edible matrix is placed in dry in 60 DEG C of baking oven and softens by S5, the edible matrix after softening is put in mixer and stirs
Mix, sequentially add step S4 gained, xylitol, hydroxyl isomaltulose, glycerine, lecithin stir in mixer, compressing tablet becomes
Type, obtains final product.
A kind of trollflower chewing gum of comparative example 1
Trollflower chewing gum is prepared from (every part is 800g) by the primary raw material of following weight parts：
128 parts of edible matrix, 8 parts of lecithin, 13 parts of glycerine, 18 parts of xylitol, 37 parts of trollflower, 7 parts of lotus leaf, loguat leaf
11 parts, 8 parts of Radix Glycyrrhizae, 7 parts of cape jasmine, 9 parts of the root of kudzu vine, 6 parts of peppermint, 7 parts of balloonflower root, 4 parts of purslane, 7 parts of perilla leaf and hydroxyl isomaltulose 4
Part.
Preparation method is similar to Example 3.
Difference with embodiment 3 is, does not add Buddha's hand, increases the parts by weight of trollflower.
A kind of chewing gum of comparative example 2
Chewing gum is prepared from (every part is 800g) by the primary raw material of following weight parts：
128 parts of edible matrix, 8 parts of lecithin, 13 parts of glycerine, 18 parts of xylitol, 33 parts of honeysuckle, 7 parts of lotus leaf, loguat leaf
11 parts, 8 parts of Radix Glycyrrhizae, 7 parts of cape jasmine, 9 parts of the root of kudzu vine, 6 parts of peppermint, 7 parts of balloonflower root, 4 parts of purslane, 7 parts of perilla leaf, 4 parts of Buddha's hand and different
4 parts of maltitol.
Preparation method is similar to Example 3.
Difference with embodiment 3 is, trollflower is replaced with honeysuckle.
Test example one：Trollflower chewing gum effect observation
1st, study subject：Select the age at 25～60 years old, 400 chronic pharyngitis of the no complication such as severe cardiac, liver, kidney are subject to
Examination person.It is randomly divided into five groups, experimental group 1-3 and control group 1, control group 2.Five groups of experimenter's no conspicuousnesses in terms of symptom are poor
Different, there is comparativity.Experimental group 1-3 uses embodiment of the present invention 1-3 products obtained therefrom, and control group 1, control group 2 are respectively using right
Ratio 1, comparative example 2 products obtained therefrom.During using embodiment 1-3 products obtained therefrom and comparative example 1, comparative example 2 products obtained therefrom,
Do not use other Related products.Using method：The daily morning and evening is each once, chews 15 minutes every time.
(1) experimenter's inclusive criteria：(1) medical history has pharyngalgia, the symptom such as pharynx is itched, dry throat is puckery, expectoration is not well, dry cough repeatedly
History of attack.(2) congestion of throat, mucosa edema are checked, swallow rear wall lymph foilicie hyperplasia have secretion to adhere to.There is above-mentioned symptom
And 1 or more than 1 inspection finding volunteer, all can carry out test-meal observation through medical fitness.
(2) exclusion standard：(1) confirm have oropharynx, nasopharynx, throat, nose, larynx, oesophagus, neck and whole body some on inspection
Person caused by invisible pathology.(2) age is in under-18s or over-65s person, gestation or women breast-feeding their children and to this product allergy
Person.(3) it is associated with the severe primary disease such as angiocarpy, liver, kidney and hemopoietic system, mental patient.(4) do not meet and include mark
Standard, does not take tested material by regulation it is impossible to judge effect or the not congruent impact effect of data or security judgement person.
2nd, efficiency observation
(1) Symptom Observation：Detailed medical history-taking, observes pharyngalgia, the symptom such as pharynx is itched, dry cough, dry throat are puckery.(2) pharyngeal inspection
Look into：Observe the signs such as pharyngeal hyperemia, pharynx rear wall FH, mucosa edema, secretion.
3rd, effect criterion
Effective：Symptom disappears or obvious mitigation；Take a turn for the better：Symptom mitigation；Invalid：Symptom and sign no significant change.Result is such as
Shown in table 1, table 2 and table 3.
Table 1：Experimental group and control group functional observation situation
Table 2：Cardinal symptom improves situation
Table 3：Pharyngeal symptom improves situation
Can be seen that compared with control group 1 and control group 2 by table 1, table 2 and table 3, experimental group 1, experimental group 2 and experimental group
The cardinal symptoms and pharynx rear wall FH, secretion, congestion of throat etc. such as the dry cough of 3 chronic pharyngitis experimenters, pharynx are itched, pharyngalgia
Sign improves significantly.This illustrate gained trollflower chewing gum of the present invention the dry cough of patients with chronic pharyngitis, pharynx are itched, pharyngalgia etc.
The improvement result of cardinal symptom is substantially, obvious to the improvement result of the signs such as pharynx rear wall FH, secretion, congestion of throat.
During using experimental example product and comparative example product, all bad reaction in all experimenters.
Claims (10)
1. a kind of trollflower chewing gum is it is characterised in that be prepared from by the primary raw material of following weight parts：
Edible matrix 120-140 part, lecithin 6-10 part, glycerine 10-15 part, xylitol 14-20 part, trollflower 30-40 part, lotus
Leaf 5-9 part, loguat leaf 10-14 part, Radix Glycyrrhizae 7-10 part, cape jasmine 5-9 part, root of kudzu vine 8-12 part, peppermint 4-8 part, balloonflower root 6-9 part, horse
Bitterroot 3-6 part, perilla leaf 5-9 part, Buddha's hand 3-5 part and hydroxyl isomaltulose 3-5 part.
2. trollflower chewing gum as claimed in claim 1 it is characterised in that by following weight parts primary raw material prepare and
Become：
128 parts of edible matrix, 8 parts of lecithin, 13 parts of glycerine, 18 parts of xylitol, 33 parts of trollflower, 7 parts of lotus leaf, loguat leaf 11
Part, 8 parts of Radix Glycyrrhizae, 7 parts of cape jasmine, 9 parts of the root of kudzu vine, 6 parts of peppermint, 7 parts of balloonflower root, 4 parts of purslane, 7 parts of perilla leaf, 4 parts of Buddha's hand and different wheat
4 parts of bud sugar alcohol.
3. the preparation method of trollflower chewing gum as claimed in claim 1 or 2 is it is characterised in that step is as follows：
S1 takes trollflower, is ground into meal, sieves, and adds ethanol, the volume fraction of ethanol is 50%～75%, the weight of ethanol
It is 12～15 times of above-mentioned trollflower meal weight, extracts at 65～75 DEG C, extract three times, extract 1.5 hours every time, merge
No. three extracts, are condensed into the thick paste that relative density is 1.32～1.36；
Lotus leaf, loguat leaf, Radix Glycyrrhizae, cape jasmine, balloonflower root, purslane, perilla leaf and Buddha's hand are cleaned by S2, are placed in extractor, add
The decocting of 9～13 times of above-mentioned 8 kinds of raw materials boils three times, decocts 2 hours for the first time, and second and third time decoct 1 hour, filtration,
Merging filtrate, being evaporated to relative density is 1.15～1.22, plus 95% ethanol, makes alcohol content reach 65%, stirs,
Standing 24 hours, takes supernatant liquor, decompression recycling ethanol, is condensed into the thick paste that relative density is 1.33～1.37；
S3 takes the root of kudzu vine, is ground into meal, crosses 50 mesh sieves, takes peppermint, is ground into meal, crosses 70 mesh sieves, by above-mentioned root of kudzu vine meal and
Peppermint meal mixes, and adds ethanol, the volume fraction of ethanol is 60%～80%, and the weight of ethanol is above-mentioned root of kudzu vine meal and thin
10～14 times of lotus meal gross weight, extract at 60～75 DEG C, extract twice, extract 2 hours for the first time, extract 1 second
Hour, merge extract twice, be condensed into the thick paste that relative density is 1.34～1.40；
Step S1 gained thick paste, step S2 gained thick paste and step S3 gained thick paste are mixed by S4；
Edible matrix is placed in dry in 55～65 DEG C of baking oven and softens by S5, the edible matrix after softening is put in mixer and stirs
Mix, sequentially add step S4 gained, xylitol, hydroxyl isomaltulose, glycerine, lecithin stir in mixer, compressing tablet becomes
Type, obtains final product.
4. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that the volume of described step S1 ethanol
Fraction is 65%.
5. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that the weight of described step S1 ethanol
It is 14 times of above-mentioned trollflower meal weight.
6. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that described step S1 carries at 70 DEG C
Take.
7. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that described step S1 is condensed into relatively
Density is 1.35 thick paste.
8. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that described step S2 adds above-mentioned 8
The decocting planting 11 times of raw material boils three times.
9. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that described step S2 is evaporated to
Relative density is 1.18.
10. the preparation method of trollflower chewing gum as claimed in claim 3 is it is characterised in that described step S2 is condensed into phase
It is 1.35 thick paste to density.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611062665.0A CN106377599A (en) | 2016-11-25 | 2016-11-25 | Trollflower chewing gum and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611062665.0A CN106377599A (en) | 2016-11-25 | 2016-11-25 | Trollflower chewing gum and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109699979A (en) * | 2019-01-04 | 2019-05-03 | 广东大鹏医药科技有限公司 | The honey and preparation method and purposes of a kind of ingredient containing trollflower in trollflower flower source |
| CN110663800A (en) * | 2019-10-29 | 2020-01-10 | 云南省药物研究所 | Notoginseng flower traditional Chinese medicine chewing gum capable of reducing internal heat and clearing throat and preparation method thereof |
| CN111296616A (en) * | 2020-02-18 | 2020-06-19 | 广东大鹏医药科技有限公司 | Chewing gum containing plant extract and preparation method thereof |
-
2016
- 2016-11-25 CN CN201611062665.0A patent/CN106377599A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109699979A (en) * | 2019-01-04 | 2019-05-03 | 广东大鹏医药科技有限公司 | The honey and preparation method and purposes of a kind of ingredient containing trollflower in trollflower flower source |
| CN110663800A (en) * | 2019-10-29 | 2020-01-10 | 云南省药物研究所 | Notoginseng flower traditional Chinese medicine chewing gum capable of reducing internal heat and clearing throat and preparation method thereof |
| CN111296616A (en) * | 2020-02-18 | 2020-06-19 | 广东大鹏医药科技有限公司 | Chewing gum containing plant extract and preparation method thereof |
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Application publication date: 20170208 |