CN104940739A - Traditional Chinese medicine composition for biliary ascariasis treating - Google Patents

Abstract

The invention discloses traditional Chinese medicine composition for biliary ascariasis treating. The traditional Chinese medicine composition is prepared by the following principal raw materials, by mass, 15-23 parts of flos mume, 9-16 parts of digenea simplex, 12-18 parts of malt, 7-15 parts of red umbilicaria, 10-16 parts of lysimachia foenum-graecum, 8-14 parts of common javatea roots, 9-15 parts of littleleaf indianmulberry roots and stems, 7-12 parts of glyptostrobus pensilis, 9-14 parts of szechwan chinaberry fruits, 10-15 parts of brainea insignis, 11-16 parts of okamura ishige algae, 9-17 parts of pumpkin seeds, 7-16 parts of assam crotalaria leaves and 11-15 parts of Caulis Fici Tikouae. The traditional Chinese medicine composition is prepared by adopting pure-natural medicinal materials, functions of the raw materials are cooperated, and the traditional Chinese medicine composition has the effects that the gallbladder is cleared and bile flow is promoted, roundworms are killed, the bowel movement is facilitated, the qi is regulated, the pain is relieved, and obvious effect is provided for the biliary ascariasis treating.

Description

The Chinese medicine composition for the treatment of ascariasis of biliary tract

Technical field

The present invention relates to traditional Chinese medicine field, particularly a kind of Chinese medicine composition for the treatment of ascariasis of biliary tract.

Background technology

Ascariasis of biliary tract is a kind of complication the most serious in intestinal ascariasis, be more common in 6-8 school age population in year, peasant and late period anemia of pregnant woman.It is that the bellyworm motion caused by a variety of causes is active, and the acute upper abdominal pain piercing biliary tract and occur or biliary tract infection.During outbreak, Principle of Pain is difficult to stand, and wails and cries, very painful.If remedy measures does not catch up with, can there is dehydration in various degree and acidosis, even threat to life in end-stage patients.

Ascarid adult parasitizes hypomere in small intestinal, and when Whole Body and digestive tract function are disorderly, as improper in high heat, diarrhoea, hunger, gastric acidity reduction, eating and drinking without temperance, anthelmintic, stimulation etc. of performing the operation, all can the abnormal movement of excitation polypide, Shang Cuandan road; In addition ascarid alkali in the family way is detested acid, is had boring habit, more easily causes adult to bore gallbladder at cholangitis, calculus and sphincter dilatation etc.The person 80% that scurries into biliary tract, in bile duct, can be bar more than 1-100.After ascarid enters biliary tract, its mechanical stimulus, causes the strong spastic contractions of sphincter, occurs biliary colic, especially the part person of piercing, and irritation more takes place frequently, and enter biliary tract completely at it or exit voluntarily, symptom can be alleviated or disappear.The ascarid great majority entering biliary tract are dead in biliary tract, and its corpse fragment, cuticle, worm's ovum are by the core of calculus after becoming.The ascarid bile duct obstruction pierced caused by biliary tract is incomplete, therefore there is jaundice very less, the antibacterial that mainly ascarid is brought into causes bile duct inflammation, and ASCT, liver abscess, subphrenic abscess, biliary peritonitis, acute pancreatitis, hemobilia, toxic shock etc. can be caused, so that dead.

At present, the medicine for the treatment of ascariasis of biliary tract is a lot, publication number CN 103285290 A(application number 201310162137.2) patent document discloses a kind of Chinese medicine composition for the treatment of ascariasis of biliary tract, be made up of following component, the weight portion of each component is: Herba Artemisiae Scopariae 20-25, Radix Aucklandiae 9-11, Fructus Aurantii 9-11, Radix Et Rhizoma Rhei 3-5, Semen Cucurbitae 4-6, leaf of Caulis Sacchari sinensis 8-10, Fructus Mume 7-9, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 3-4, Pericarpium Zanthoxyli 2-5, Omphalia 2-4, Scorpio 6-8, Radix Notoginseng 9-11, Semen Sinapis Albae 4-6, Radix Ilicis Asprellae 2-4, Radix Bupleuri 8-10, Sargassum 5-8, Rhizoma Sparganii 4-6, Caulis Bambusae In Taenia 1-3 and Cortex Meliae 5-7.Publication number CN 104523949 A(application number 201510034900.2) patent document discloses a kind of medicine being used for the treatment of ascariasis of biliary tract, it is prepared from by the raw medicinal material of following weight proportion: Fructus Mume 9 parts, Cortex Phellodendri 8 parts, Fructus Zanthoxyli 6 parts, Fructus Toosendan 6 parts.Publication number CN 103638501 A(application number 201310671774.2) patent document discloses a kind of medicine for the treatment of ascariasis of biliary tract and preparation method thereof, it is made up of the crude drug in following weight range: Semen Arecae 15-25 gram, Cortex Magnoliae Officinalis 10-20 gram, Fructus Quisqualis 15-25 gram, Pericarpium Zanthoxyli 5-15 gram, Pericarpium Arecae 10-20 gram, Endothelium Corneum Gigeriae Galli 10-20 gram, Radix Codonopsis 15-25 gram, Herba Lysimachiae 5-15 gram, Fructus Jujubae 15-25 gram, Rhizoma Zingiberis 15-25 gram, Radix Et Rhizoma Rhei 10-20 gram, Herba Taraxaci 15-25 gram, Herba Pogostemonis 5-15 gram, Rhizoma Osmundae 5-15 gram, Concha Ostreae 15-25 gram, Herba Asari 15-25 gram, Folium Sennae 10-20 gram, Cortex Meliae 3-9 gram, Rhizoma Pinelliae 5-15 gram, Fructus Mume 5-15 gram, Alumen 15-25 gram, Semen Torreyae 25-35 gram.

At present, treating biliary ascariasis mainly adopts operative treatment, antihelminthic chemotherapy, ERCP to get the method treatments such as worm.Operative treatment easily brings larger misery to patient; Antihelminthic chemotherapy easily makes polypide remains be retained in gallbladder and form cholelithiasis; ERCP gets worm can only take out part ascarid.So western medicine ascariasis of biliary tract poor effect, there is the deficiencies such as therapeutic effect is poor, treatment time is long, side effect is large.Although some medicines have appearred in traditional Chinese medical science aspect, curative effect is also indefinite.

Summary of the invention

For the deficiencies in the prior art, an object of the present invention is to provide a kind of Chinese medicine composition for the treatment of ascariasis of biliary tract, there is clearing gallbladder function of gallbladder promoting, kill ascarid purging FU-organs, regulating QI to relieve pain, relieving colic caused by ascaris anthelmintic effect, treatment ascariasis of biliary tract evident in efficacy.Another object of the present invention is just to provide the preparation method of the Chinese medicine composition of above-mentioned treatment ascariasis of biliary tract.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

The Chinese medicine composition for the treatment of ascariasis of biliary tract, takes off the primary raw material stating weight proportion and is prepared from: Flos Pruni mume 15-23 part; Digenea simplex (Wnlf.) C. Ag. 9-16 part; Fructus Hordei Germinatus 12-18 part; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 7-15 part; Herba Lysimachiae foenum-graeci 10-16 part; Radix Orthosiphonis Wulfenioidis 8-14 part; Herba Morindae Parvifoliae 9-15 part; Codium fragile (Sur.) Har. 7-12 part; Fructus Toosendan 9-14 part; Brainea insignis 10-15 part; Ishige okamurae Yendo 11-16 part; Semen Cucurbitae 9-17 part; Caulis et Folium Crotalariae Assamicae 7-16 part; Caulis et Folium fici Tikouae 11-15 part.

The Chinese medicine composition for the treatment of ascariasis of biliary tract, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Flos Pruni mume 18-20 part; Digenea simplex (Wnlf.) C. Ag. 12-14 part; Fructus Hordei Germinatus 14-16 part; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 10-12 part; Herba Lysimachiae foenum-graeci 12-14 part; Radix Orthosiphonis Wulfenioidis 10-12 part; Herba Morindae Parvifoliae 11-13 part; Codium fragile (Sur.) Har. 9-11 part; Fructus Toosendan 11-13 part; Brainea insignis 12-14 part; Ishige okamurae Yendo 13-15 part; Semen Cucurbitae 12-14 part; Caulis et Folium Crotalariae Assamicae 11-13 part; Caulis et Folium fici Tikouae 12-14 part.

The Chinese medicine composition for the treatment of ascariasis of biliary tract, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Flos Pruni mume 19 parts; Digenea simplex (Wnlf.) C. Ag. 13 parts; 15 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 11 parts; Herba Lysimachiae foenum-graeci 13 parts; Radix Orthosiphonis Wulfenioidis 11 parts; Herba Morindae Parvifoliae 12 parts; Codium fragile (Sur.) Har. 10 parts; Fructus Toosendan 12 parts; Brainea insignis 13 parts; Ishige okamurae Yendo 14 parts; Semen Cucurbitae 13 parts; Caulis et Folium Crotalariae Assamicae 12 parts; Caulis et Folium fici Tikouae 13 parts.

Present invention also offers the preparation method Chinese medicine composition of above-mentioned treatment ascariasis of biliary tract being made pharmaceutically acceptable powder, decoction, pill, tablet and granule.

The preparation method of the Chinese medicine composition composition powders of described treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire fried dry, dry in the air cool, porphyrize, excessively 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, was more preferably 150 mesh sieves);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are dried, pulverize, excessively 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, was more preferably 150 mesh sieves);

(4) by step (1)-(3) gained fine powder mix homogeneously, sterile packaged.

Instructions of taking: at every turn get 8-10g, is placed in tea bag, soaks, every day 2-3 time, 2 days courses for the treatment of by the warm waters of about 50 DEG C.

The preparation method of the Chinese medicine composition decoction of described treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar, moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, be concentrated into 1/2 of original volume, obtain decoction.

The preparation method of the Chinese medicine composition decoction of above-mentioned treatment ascariasis of biliary tract, the consumption of the preferred rice vinegar of step (2) is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%.

Instructions of taking: each 150-200ml, every day 2 times, 2 days courses for the treatment of.

The preparation method of the Chinese medicine composition pill of described treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour and (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, being condensed into relative density is 1.10-1.20(40 DEG C) thick paste (be preferably condensed into the thick paste that relative density is 1.13-1.17, be more preferably and be condensed into the thick paste that relative density is 1.15), make pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm).

Instructions of taking: each 10-15 ball, every day 3 times, 2 days courses for the treatment of.

The preparation method of the Chinese medicine composition tablet of described treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour and (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, being condensed into relative density is 1.10-1.20(40 DEG C) thick paste (be preferably condensed into the thick paste that relative density is 1.13-1.17, be more preferably and be condensed into the thick paste that relative density is 1.15), make tablet.

Instructions of taking: each 2-3 sheet, every day 3 times, 2 days courses for the treatment of.

The preparation method of the Chinese medicinal composition granules of described treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour and (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, being condensed into relative density is 1.10-1.20(40 DEG C) thick paste (be preferably condensed into the thick paste that relative density is 1.13-1.17, be more preferably and be condensed into the thick paste that relative density is 1.15), add simple syrup, mixing, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.

The preparation method of the Chinese medicinal composition granules of above-mentioned treatment ascariasis of biliary tract, the consumption of the preferred simple syrup of step (4) is the 5%-7% of thick paste quality, and the consumption being more preferably simple syrup is 6% of thick paste quality.

Instructions of taking: each 1 bag, every day 3 times, 2 days courses for the treatment of.

Technical advantage of the present invention is mainly reflected in:

1, the present invention adopts pure natural medical material to prepare, and quality of medicinal material is superior, and drug effect is lastingly powerful, safe and reliable, does not injure the intestines and stomach, can not produce drug dependence.

2, each raw material effect of the present invention is worked in coordination with, there is clearing gallbladder function of gallbladder promoting, kill ascarid purging FU-organs, regulating QI to relieve pain, relieving colic caused by ascaris anthelmintic effect, treatment ascariasis of biliary tract evident in efficacy.

3, selected materials great majority of the present invention are Chinese medicine material, and medical material is easy to get, and cost is low.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1the Chinese medicine composition for the treatment of ascariasis of biliary tract, takes off the primary raw material stating weight proportion and is prepared from (getting 40g for every part): Flos Pruni mume 15 parts; Digenea simplex (Wnlf.) C. Ag. 9 parts; 12 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 7 parts; Herba Lysimachiae foenum-graeci 10 parts; Radix Orthosiphonis Wulfenioidis 8 parts; Herba Morindae Parvifoliae 9 parts; Codium fragile (Sur.) Har. 7 parts; Fructus Toosendan 9 parts; Brainea insignis 10 parts; Ishige okamurae Yendo 11 parts; Semen Cucurbitae 9 parts; Caulis et Folium Crotalariae Assamicae 7 parts; Caulis et Folium fici Tikouae 11 parts.

The preparation method of the Chinese medicine composition composition powders of above-mentioned treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 8 minutes, take out, be placed in cold water immediately to soak 13 minutes, take out, dry, be placed in glass container, add the dense sugar liquid (every 100ml pure water dissolves with crystal sugar 135g and forms) being equivalent to Brainea insignis quality 4 times, soak 23 hours, take out, wash away floating sugar, drying, porphyrize, crosses 150 mesh sieves;

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar (consumption be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 4 hours, is placed in parch container, slow fire fried dry, dry in the air cool, porphyrize, crosses 150 mesh sieves;

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are dried, pulverize, cross 150 mesh sieves;

(4) by step (1)-(3) gained fine powder mix homogeneously, sterile packaged.

Instructions of taking: at every turn get 10g, is placed in tea bag, soaks, every day 3 times, 2 days courses for the treatment of by the warm waters of about 50 DEG C.

embodiment 2the Chinese medicine composition for the treatment of ascariasis of biliary tract, takes off the primary raw material stating weight proportion and is prepared from (every part of 20g): Flos Pruni mume 23 parts; Digenea simplex (Wnlf.) C. Ag. 16 parts; 18 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 15 parts; Herba Lysimachiae foenum-graeci 16 parts; Radix Orthosiphonis Wulfenioidis 14 parts; Herba Morindae Parvifoliae 15 parts; Codium fragile (Sur.) Har. 12 parts; Fructus Toosendan 14 parts; Brainea insignis 15 parts; Ishige okamurae Yendo 16 parts; Semen Cucurbitae 17 parts; Caulis et Folium Crotalariae Assamicae 16 parts; Caulis et Folium fici Tikouae 15 parts.

The preparation method of the Chinese medicine composition decoction of above-mentioned treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 8 minutes, take out, be placed in cold water immediately to soak 13 minutes, take out, dry, be placed in glass container, add the dense sugar liquid (every 100ml pure water dissolves with crystal sugar 135g and forms) being equivalent to Brainea insignis quality 4 times, soak 23 hours, take out, wash away floating sugar, drying, porphyrize, crosses 150 mesh sieves;

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar (consumption be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 4 hours, be placed in parch container, slow fire fries 35 minutes;

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 45 minutes, add step (2) gains, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 5 hours, filter, be concentrated into 1/2 of original volume, obtain decoction.

Instructions of taking: each 200ml, every day 3 times, 2 days courses for the treatment of.

model case onehigh XX, man, 25 years old, people from Accessories during Binzhou, Shandong Province.The business of Mr.'s Gao do-it-yourself electronic product, the friend contacted at ordinary times is many, and likes a few individual to get together eating barbecue having the beer.Once before more than 1 year without obvious inducement under start to occur stomachache, be just eased after each drug administration.Nearest Mr.'s high stomachache takes place frequently, and epigastrium continues angor, companion's nausea and vomiting, so go examination in hospital to find skin sclera severe xanthochromia, upper right abdominal pressure pain, B ultrasonic and CT examination display gallbladder increase, and choledochectasia, extrahepatic duct is also obviously expanded.Be diagnosed as ascariasis of biliary tract, infusion treatment is alleviated without obvious for 3 days.

Take after the present invention treats 2 courses for the treatment of of Chinese medicine composition (embodiment 2) of ascariasis of biliary tract, the symptoms such as stomachache, nausea and vomiting obviously alleviate.After continuing to take 2 courses for the treatment of, all malaise symptoms disappear, and gallbladder, common bile duct, extrahepatic duct are all normal on inspection, reach clinical cure.Tracing observation learns recovery from illness, without recurrence.

embodiment 3the Chinese medicine composition for the treatment of ascariasis of biliary tract, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Flos Pruni mume 18 parts; Digenea simplex (Wnlf.) C. Ag. 12 parts; 14 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 10 parts; Herba Lysimachiae foenum-graeci 12 parts; Radix Orthosiphonis Wulfenioidis 10 parts; Herba Morindae Parvifoliae 11 parts; Codium fragile (Sur.) Har. 9 parts; Fructus Toosendan 11 parts; Brainea insignis 12 parts; Ishige okamurae Yendo 13 parts; Semen Cucurbitae 12 parts; Caulis et Folium Crotalariae Assamicae 11 parts; Caulis et Folium fici Tikouae 12 parts.

The preparation method of the Chinese medicine composition pill of above-mentioned treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 8 minutes, take out, be placed in cold water immediately to soak 13 minutes, take out, dry, be placed in glass container, add the dense sugar liquid (every 100ml pure water dissolves with crystal sugar 135g and forms) being equivalent to Brainea insignis quality 4 times, soak 23 hours, take out, wash away floating sugar, drying, porphyrize, crosses 150 mesh sieves;

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar (consumption be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 4 hours, be placed in parch container, slow fire fries 35 minutes;

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 45 minutes, add step (2) gains, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 5 hours, filter, being condensed into relative density is 1.15(40 DEG C) thick paste, make the pill that diameter is 4mm.

Instructions of taking: each 10 balls, every day 3 times, 2 days courses for the treatment of.

embodiment 4the Chinese medicine composition for the treatment of ascariasis of biliary tract, takes off the primary raw material stating weight proportion and is prepared from (getting 25g for every part): Flos Pruni mume 20 parts; Digenea simplex (Wnlf.) C. Ag. 14 parts; 16 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 12 parts; Herba Lysimachiae foenum-graeci 14 parts; Radix Orthosiphonis Wulfenioidis 12 parts; Herba Morindae Parvifoliae 13 parts; Codium fragile (Sur.) Har. 11 parts; Fructus Toosendan 13 parts; Brainea insignis 14 parts; Ishige okamurae Yendo 15 parts; Semen Cucurbitae 14 parts; Caulis et Folium Crotalariae Assamicae 13 parts; Caulis et Folium fici Tikouae 14 parts.

The preparation method of the Chinese medicine composition tablet of above-mentioned treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 8 minutes, take out, be placed in cold water immediately to soak 13 minutes, take out, dry, be placed in glass container, add the dense sugar liquid (every 100ml pure water dissolves with crystal sugar 135g and forms) being equivalent to Brainea insignis quality 4 times, soak 23 hours, take out, wash away floating sugar, drying, porphyrize, crosses 150 mesh sieves;

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar (consumption be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 4 hours, be placed in parch container, slow fire fries 35 minutes;

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 45 minutes, add step (2) gains, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 5 hours, filter, being condensed into relative density is 1.15(40 DEG C) thick paste, make tablet.

Instructions of taking: each 2, every day 3 times, 2 days courses for the treatment of.

model case twoconsolidate XX, female, 28 years old, people from Liaocheng of Shandong Province.Right hypochondrial region was there is without obvious inducement before 3 years, with lower back radiating pain, sharp ache, with heating, the discomforts such as nausea and vomiting.Go to see a doctor, abdominal part is full, and abdomen is soft, the dark tenderness of upper right abdomen.Abdominal CT: Intrahepatic Bile Duct Dilation, cystic duct, common hepatic duct, common bile duct are shown in tubulose high density stove.Diagnosis: ascariasis of biliary tract, gives infusion treatment 3 days, stomachache is alleviated.But recurrent exerbation right hypochondrial region afterwards, frequent before right hypochondrial region outbreak comparatively closely over the past half year, degree increases the weight of.

Take after the present invention treats 2 courses for the treatment of of Chinese medicine composition (embodiment 4) of ascariasis of biliary tract, symptom obviously alleviates, and abdominal pain also obviously alleviates.After continuing to take 2 courses for the treatment of, go to hospital to check and learn that indices reaches normal level.Later stage follows up a case by regular visits to and learns and fully recover, without recurrence.

embodiment 5the Chinese medicine composition for the treatment of ascariasis of biliary tract, takes off the primary raw material stating weight proportion and is prepared from (getting 30g for every part): Flos Pruni mume 19 parts; Digenea simplex (Wnlf.) C. Ag. 13 parts; 15 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 11 parts; Herba Lysimachiae foenum-graeci 13 parts; Radix Orthosiphonis Wulfenioidis 11 parts; Herba Morindae Parvifoliae 12 parts; Codium fragile (Sur.) Har. 10 parts; Fructus Toosendan 12 parts; Brainea insignis 13 parts; Ishige okamurae Yendo 14 parts; Semen Cucurbitae 13 parts; Caulis et Folium Crotalariae Assamicae 12 parts; Caulis et Folium fici Tikouae 13 parts.

The preparation method of the Chinese medicinal composition granules of above-mentioned treatment ascariasis of biliary tract, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 8 minutes, take out, be placed in cold water immediately to soak 13 minutes, take out, dry, be placed in glass container, add the dense sugar liquid (every 100ml pure water dissolves with crystal sugar 135g and forms) being equivalent to Brainea insignis quality 4 times, soak 22 hours, take out, wash away floating sugar, drying, porphyrize, crosses 150 mesh sieves;

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar (consumption be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 4 hours, be placed in parch container, slow fire fries 35 minutes;

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 45 minutes, add step (2) gains, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 5 hours, filter, being condensed into relative density is 1.15(40 DEG C) thick paste, add simple syrup, mixing, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.

Instructions of taking: each 1 bag, every day 3 times, 2 days courses for the treatment of.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Flos Pruni mume: sour in the mouth, puckery, property is put down.Return liver, stomach, lung meridian.For the dry flower of rose department plant plum.There is soothing liver-QI, stomach function regulating, the effect of reducing phlegm.For globus hystericus, stomachache due to hyperactive liver-QI attacking the stomach, inappetence, dizzy, scrofula.

Digenea simplex (Wnlf.) C. Ag.: salty in the mouth, property is put down.Return large intestine channel.For the frond of Rhodomelaceae Digenea plant Digenea simplex (Wnlf.) C. Ag..Containing kainic acid and a small amount of other kainic acid, still containing polysaccharide such as agar, the glycoside be made up of glyceric acid and mannose, volatile oil, aminoacid, peptide, organic acid etc., containing iodine 0.2%, betanin etc.There is effect of anthelmintic.For ascarid, whipworm, cestode disease.

Fructus Hordei Germinatus: sweet in the mouth, property is put down.Return spleen, stomach warp.For the mature fruit of grass Fructus Hordei Vulgaris is through germinateing drying and obtaining.There is spleen benefiting and stimulating the appetite, move back effect of newborn relieving distension.Do not disappear for food stagnation, women weans; Fructus Hordei Germinatus (parched to brown) relieving dyspepsia, does not disappear for food stagnation, abdominal distention.

Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.): lightly seasoned, micro-hardship, property is put down.Return stomach warp.For the thallus of the red abdomen Umbillcaria esculenta of Umbilicariaceae Umbilcaria plant.Containing gyrophoric acid, black bitter edible plant stain element, methyl orsellinate and ethyl orsellinate, moss, methyl β-orcinolcarboxylate, usnic acid, 2,2-two [(1,8-bis-base-3-methyl) mattress quinone].There is stomach invigorating of regulating the flow of vital energy, effect of diuretic de-swelling.For dyspepsia, abdominal distention, dysentery, infantile malnutrition.

Herba Lysimachiae foenum-graeci: acrid in the mouth, sweet, property is put down.Attach to the lung and stomach meridians.For the herb of Primulaceae Lysimachia plant Herba Lysimachiae foenum-graeci.Containing volatile oil, organic acid, alkane, terpenoid, phenols etc.Main component has nonacosane, hentriacontane.Stigmasterol, stigmasterol-3-O-B-D-glycoside, a-spinasterol, 12-methyl tridecanoic acid, behenic acid, 16-methylheptadecanoic acid methyl ester, hexadecylic acid, heptadecanoic acid and cyclohexane-carboxylix acid.Have and induce sweat, ward off dirty, analgesia, drives effect of ascarid.For influenza, pestilence is had a headache, laryngopharynx swelling and pain, toothache, distension and fullness of the chest and abdomen, ascariasis.

Radix Orthosiphonis Wulfenioidis: acrid in the mouth, sweet, property is put down.For the root of Labiatae Radix Orthosiphonis Wulfenioidis platymiscium Radix Orthosiphonis Wulfenioidis.There is expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, effect of killing insect and eliminating accumulation.For rheumatic arthralgia, stranguria, edema, traumatic injury, fracture, dyspeptic abdominal distention, abdominal pain due to worm stagnation.

Herba Morindae Parvifoliae: sweet in the mouth, cool in nature.Return lung meridian.For the Herb of Rubiaceae Morinda plant spire Radix Morindae Officinalis.Containing anthraquinone component: Herba Morindae Parvifoliae quinone A, B, rubican-1-methyl ether, the fixed-w-ether of gloss, the fixed-w-methyl ether of gloss, rust Folium Digitalis Purpureae chinol, 1-hydroxyl-6-or 7-methylol anthraquinone and 2-methylol anthraquinone.There is clearing and antitussive, stomach function regulating removing dampness, effect of eliminating stasis to stop pain.For cold cough, pertussis, dyspepsia, eczema, traumatic injury, lumbar muscle strain.

Codium fragile (Sur.) Har.: sweet in the mouth, salty, cold in nature.Return bladder, large intestine channel.For Codiaceae Korean pine platymiscium Codiumfragile(sur.) Hariot. and the frond growing loose algae.There is summer heat clearing toxin resolving, diuretic, effect of anthelmintic.For heatstroke, edema, dysuria, ascariasis.

Fructus Toosendan: bitter in the mouth, cold in nature.Return liver, small intestinal, urinary bladder channel.Another name is Fructus Toosendan, Fructus Toosendan, Fructus Toosendan are real.For the dry mature fruit of Meliaceae plant Fructus Toosendan, primary medicinal component is Fructus Toosendan element, alkaloid etc.There are soothing liver-QI promoting the circulation of QI to relieve pain, effect of anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.Bitter cold is fallen and is let out, can clearing away liver-fire, let out hot and suffocating, promoting the circulation of QI to relieve pain.

Brainea insignis: taste is micro-puckery, cool in nature.For the rhizome of Blechnaceae Brainea insignis platymiscium Brainea insignis.Containing dryocrassin.There is heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, effect of anthelmintic.For flu, traumatic hemorrhage, ascariasis.

Ishige okamurae Yendo: salty in the mouth, cold in nature.Return Liver Channel.For the frond of Ishigeaceae Ishige okamurae Yendo platymiscium Ishige okamurae Yendo and lobate Ishige okamurae Yendo.Containing DG base methylol trimethyl-Beta-alanine and phosphatidylcholine.Also containing alginate, glucosan, alginic acid, crude protein, mannitol, potassium, iodine etc.Have hard masses softening and resolving, removing toxic substances, drives effect of ascarid.Swell for lymphonodi cervicales, goiter, laryngitis, ascariasis.

Semen Cucurbitae: sweet in the mouth, property is put down.Return large intestine channel.For the seed of Cucurbitaceae cucurbita plants Fructus Cucurbitae moschatae.Oil-containing 16.4%, wherein main fatty acid is linoleic acid, oleic acid, Palmic acid and stearic acid, also has linolenic acid, myristic acid.Also containing lipid composition, inside have triacylglycerol, triacylglycerol, single phatidylcholine, phosphatidyl is hydramine, Phosphatidylserine, cerebroside etc.Effective ingredient is got: Cucurbitin in the kind of defat.There is parasite killing, stimulating milk secretion, effect of inducing diuresis to remove edema.For cestode, ascarid, schistosomicide, ancylostome, enterobiasis, puerperal hypogalactia, puerperal brothers' edema, pertussis, hemorrhoid.

Caulis et Folium Crotalariae Assamicae: lightly seasoned, slightly cool in nature.Return lung, spleen channel.For the stem and leaf of the large Herba crotalariae mucronatae of pulse family Genus Crotalaria Linn.Containing monocrotaline.There is heat-clearing and toxic substances removing, cooling blood for hemostasis, effect of inducing diuresis to remove edema.For cough due to lung-heat, spitting of blood, edema, renal calculus, cystitis, rheumatic ostalgia, children's's head sore, aphtha, toothache, traumatic injury, traumatic hemorrhage.

Caulis et Folium fici Tikouae: bitter in the mouth, cold in nature.Return lung, liver, spleen three warp.Another name: Fructus Fici tikouae, Caulis Entadae, Ipomoea hungaiensis Lingelsh. Et Borza. etc.For stem, the leaf of moraceae plants Radix Pachyrhizi Erosi.There is heat clearing away, dampness removing, invigorate blood circulation, effect of removing toxic substances.For cough due to pathogenic wind-heat, dysentery, edema, jaundice, rheumatalgia, bleeding hemorrhoids, amenorrhea, leukorrhagia, infantile dyspepsia, traumatic injury, innominate toxic swelling.

test examplein order to verify that the present invention treats the curative effect of the Chinese medicine composition (embodiment 5) of ascariasis of biliary tract, do contrast test in February ,-2011 in June, 2009:

General data: screening 280 routine ascariasis of biliary tract patient, wherein male patient 117 people, female patient 163 people; Minimal ages 3 years old, max age 62 years old, 23.8 years old mean age; 4-10 year 152 people, 11-30 year 39 people, 31-50 year 51 people, 51-62 year 38 people.Be divided into experimental group and matched group two groups (wherein experimental group 180 people, matched group 100 people) at random, two groups are compared there was no significant difference, have comparability in sex, age, the course of disease, state of an illness scoring etc.

Diagnostic criteria: 1. typical clinical manifestation: under there is suddenly epigastrium xiphoid-process, paroxysmal " brill top " sample has an intense pain or angor, and xiphoid-process lower right has slight dark tenderness but stomach wall is still flat soft; 2. B ultrasonic shows choledochectasia, parallel light belt of can visiting and be separated by common bile duct or in gallbladder, meets biliary tract ascarid diagnosis.

Usage and dosage: experimental group takes the Chinese medicinal composition granules that the present invention treats ascariasis of biliary tract, each 1 bag, every day 3 times, 2 days courses for the treatment of.Matched group uses other medicine (example hydrochloric acid Ergamisole, mebendazole sheet etc.), and wherein, levamisole hydrochloride tablets: oral, adult 3/5-1 sheet/10kg, empty stomach or decoction being taken at a draught before sleeping, child dose is 1/10kg.Mebendazole sheet: every day 2 times, serve on 3 by each 1, and adult and child all take by above-mentioned dosage.

Criterion of therapeutical effect: cure: stomachache disappears, and B surpasses inspection and shows that ascarid is discharged completely; Effective: stomachache disappears, B surpasses inspection and shows that polypide is broken discharge; Invalid: stomachache continues not alleviate, B is super to be checked without taking a turn for the better.

Take the matched group of other drug and take the Comparison of therapeutic that the present invention treats the experimental group of the Chinese medicine composition of ascariasis of biliary tract, result is as shown in table 1:

Table 1

As can be seen from Table 1, take the present invention and treat the cure rate of the Chinese medicine composition of ascariasis of biliary tract up to 72.23%, effective percentage is up to 96.67%; And the cure rate taking other drug only 41%, effective percentage also only has 79%.So the successful that the present invention treats the Chinese medicine composition of ascariasis of biliary tract is better than the effect of other drug.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or obtain undoubtedly according to the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the Chinese medicine composition of ascariasis of biliary tract, it is characterized in that, take off the primary raw material stating quality proportioning and be prepared from: Flos Pruni mume 15-23 part; Digenea simplex (Wnlf.) C. Ag. 9-16 part; Fructus Hordei Germinatus 12-18 part; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 7-15 part; Herba Lysimachiae foenum-graeci 10-16 part; Radix Orthosiphonis Wulfenioidis 8-14 part; Herba Morindae Parvifoliae 9-15 part; Codium fragile (Sur.) Har. 7-12 part; Fructus Toosendan 9-14 part; Brainea insignis 10-15 part; Ishige okamurae Yendo 11-16 part; Semen Cucurbitae 9-17 part; Caulis et Folium Crotalariae Assamicae 7-16 part; Caulis et Folium fici Tikouae 11-15 part.

2. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material stating quality proportioning and is prepared from: Flos Pruni mume 18-20 part; Digenea simplex (Wnlf.) C. Ag. 12-14 part; Fructus Hordei Germinatus 14-16 part; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 10-12 part; Herba Lysimachiae foenum-graeci 12-14 part; Radix Orthosiphonis Wulfenioidis 10-12 part; Herba Morindae Parvifoliae 11-13 part; Codium fragile (Sur.) Har. 9-11 part; Fructus Toosendan 11-13 part; Brainea insignis 12-14 part; Ishige okamurae Yendo 13-15 part; Semen Cucurbitae 12-14 part; Caulis et Folium Crotalariae Assamicae 11-13 part; Caulis et Folium fici Tikouae 12-14 part.

3. Chinese medicine composition according to claim 1, is characterized in that, takes off the primary raw material stating quality proportioning and is prepared from: Flos Pruni mume 19 parts; Digenea simplex (Wnlf.) C. Ag. 13 parts; 15 parts, Fructus Hordei Germinatus; Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.) 11 parts; Herba Lysimachiae foenum-graeci 13 parts; Radix Orthosiphonis Wulfenioidis 11 parts; Herba Morindae Parvifoliae 12 parts; Codium fragile (Sur.) Har. 10 parts; Fructus Toosendan 12 parts; Brainea insignis 13 parts; Ishige okamurae Yendo 14 parts; Semen Cucurbitae 13 parts; Caulis et Folium Crotalariae Assamicae 12 parts; Caulis et Folium fici Tikouae 13 parts.

4., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, the preparation method of described powder, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire fried dry, dry in the air cool, porphyrize, excessively 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, was more preferably 150 mesh sieves);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are dried, pulverize, excessively 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, was more preferably 150 mesh sieves);

(4) by step (1)-(3) gained fine powder mix homogeneously, sterile packaged.

5., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, the preparation method of described decoction, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, add rice vinegar, moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, be concentrated into 1/2 of original volume, obtain decoction.

6. the preparation method of Chinese medicine composition decoction according to claim 5, it is characterized in that: the consumption of the preferred rice vinegar of step (2) is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%.

7., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, the preparation method of described pill, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour and (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, be condensed into the thick paste (be preferably condensed into the thick paste that relative density is 1.13-1.17, be more preferably and be condensed into the thick paste that relative density is 1.15) that relative density is 1.10-1.20, make pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm).

8., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, the preparation method of described tablet, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leave standstill 4-6 hour and (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, be condensed into the thick paste (be preferably condensed into the thick paste that relative density is 1.13-1.17, be more preferably and be condensed into the thick paste that relative density is 1.15) that relative density is 1.10-1.20, make tablet.

9., according to the arbitrary described Chinese medicine composition of claim 1-3, it is characterized in that, the preparation method of described granule, step is as follows:

(1) Brainea insignis is cleaned, be placed in boiling water leaching and scald 6-10 minute (the preferably boiling hot 7-9 minute of leaching, be more preferably leaching to scald 8 minutes), take out, be placed in cold water immediately and soak 10-15 minute (preferably immersion 12-14 minute, be more preferably immersion 13 minutes), take out, dry, be placed in glass container, (preferably every 100ml pure water dissolves with crystal sugar 130g-140g and forms to add the dense sugar liquid being equivalent to Brainea insignis quality 3-5 times, be more preferably every 100ml pure water to form with crystal sugar 135g dissolving), soak 20-25 hour, take out, wash away floating sugar, dry, porphyrize, cross 140-160 mesh sieve (preferred 146-154 mesh sieve excessively, be more preferably 150 mesh sieves),

(2) Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo are cleaned, smash, be placed in non iron container, (consumption of preferred rice vinegar is the 10%-20% of Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass to add rice vinegar, the consumption being more preferably rice vinegar be Digenea simplex (Wnlf.) C. Ag., Fructus Hordei Germinatus, Umbilicaria hypococcina (Jatta) Llano. (Gyrophora tornata Ach．,Dermatocarpon miniatum(L.) Mann.), Codium fragile (Sur.) Har. and Ishige okamurae Yendo gross mass 15%), moistening 3-5 hour, be placed in parch container, slow fire is fried 30-40 minute (preferred slow fire fries 33-37 minute, is more preferably slow fire and fries 35 minutes);

(3) Flos Pruni mume, Herba Lysimachiae foenum-graeci, Radix Orthosiphonis Wulfenioidis, Herba Morindae Parvifoliae, Fructus Toosendan, Semen Cucurbitae, Caulis et Folium Crotalariae Assamicae and Caulis et Folium fici Tikouae are placed in marmite, soak 40-50 minute, add step (2) gains, decoct twice, boil at every turn and (preferably boil 33-37 minute in 30-40 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, leaves standstill 4-6 hour (preferably leave standstill 4.5-5.5 hour, be more preferably standing 5 hours), filter, be condensed into the thick paste (be preferably condensed into the thick paste that relative density is 1.13-1.17, be more preferably and be condensed into the thick paste that relative density is 1.15) that relative density is 1.10-1.20, add simple syrup, mixing, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.

10. the preparation method of Chinese medicinal composition granules according to claim 9, is characterized in that: the consumption of the preferred simple syrup of step (4) is the 5%-7% of thick paste quality, and the consumption being more preferably simple syrup is 6% of thick paste quality.