CN104435744A - Traditional Chinese medicine thick paste for treating functional dyspepsia and preparation method of traditional Chinese medicine thick paste - Google Patents
Traditional Chinese medicine thick paste for treating functional dyspepsia and preparation method of traditional Chinese medicine thick paste Download PDFInfo
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- CN104435744A CN104435744A CN201410527583.3A CN201410527583A CN104435744A CN 104435744 A CN104435744 A CN 104435744A CN 201410527583 A CN201410527583 A CN 201410527583A CN 104435744 A CN104435744 A CN 104435744A
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Abstract
The invention discloses a traditional Chinese medicine thick paste for treating functional dyspepsia. The traditional Chinese medicine thick paste is prepared from the following main raw materials in parts by weight: 6-10 parts of erigeron annuus, 10-20 parts of raphanus sativus L, 15-25 parts of sweet potatoes, 5-10 parts of sea-buckthorn, 15-25 parts of hawthorn, 15-20 parts of rhizoma cyperi, 15-23 parts of pinellia ternate, 18-24 parts of hericium erinaceus, 9-16 parts of dendrobe, 10-20 parts of honey, 8-20 parts of folium eriobotryae and 12-20 parts of agastache rugosus. The traditional Chinese medicine thick paste disclosed by the invention is simple to prepare, convenient to take and carry and easy to take for a long time and has the functions of tonifying spleen and warming the middle warmer, promoting the circulation of qi and calming the adverse-rising energy, removing food retention and stagnancy, purgating heat and bowels, soothing the liver and purging intense heat and eliminating dampness and fullness.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of traditional Chinese medicine thick paste and method for making for the treatment of functional dyspepsia.
Background technology
Functional dyspepsia (FD), also known as dyspepsia, refers to have the malaise symptoms such as upper abdominal pain, big belly, early full, belch, inappetence, Nausea and vomiting, gets rid of the one group of clinical syndrome causing the organic disease of above-mentioned symptom on inspection.Sustainable or the recurrent exerbation of symptom, accumulative more than 12 weeks in course of disease December more than month or in the past.FD is modal a kind of functional gastrointestinal disorder clinically.
Dyspepsia is a kind of clinical syndrome, the disease caused by gastric motility disorder, also comprises the bad gastroparesis of gastric peristalsis and esophageal reflux disease.Generally show as abdominal distention, easily full, acid regurgitation, belch, some patients also have the symptoms such as Nausea and vomiting.Dyspepsia is mainly divided into functional dyspepsia and Organic dyspepsia, and most dyspepsia is the functional dyspepsia (> 50%) being difficult to find the definite cause of disease.Organic dyspepsia has the clear and definite cause of disease, as peptic ulcer, erosive gastritis, esophagitis and malignant tumor etc.Functional dyspepsia refers to that the course of disease is more than 6 months, involves the non-ucler dyspepsia of indigestion symptom more than 3 months.Cardinal symptom is epigastrium pain, epigastrium burn feeling, post-prandial fullness or early full, and routine examination does not find the organic disease can explaining symptom.At present, the method for not effecting a radical cure clinically, just to alleviate or to control symptom for therapeutic goal.Conventional cushion kind comprises: acid suppression medicine, dynamics-promoting medicine, mucosa protection medicine, psychology and spiritual regulating drug etc., the deficiency of easy recurrent exerbation after there is drug withdrawal.
The traditional Chinese medical science is thought, functional dyspepsia belongs to the category such as " gastral cavity painful abdominal mass ", " stomachache ", " noisy " of the traditional Chinese medical science, and its disease, at stomach, relates to the internal organs such as liver spleen, should determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.The mainly diet retardance of its pathogenic factor, damp and hot middle resistance, feelings will are become estranged, weakness of the spleen and stomach, and basic pathogenesis is middle burnt disorder of QI movement, taste lifting dereliction of duty.
According to theory of Chinese medical science, for the pathogeny of functional dyspepsia, carry out dialectical composition of prescription, with invigorating the spleen and regulating the stomach, depressed liver-energy dispersing and QI regulating, dyspepsia and intestinal stasis relieving for the rule for the treatment of, to reach the object for the treatment of both the principal and the secondary aspects of a disease at the same time.
The Chinese patent literature of Authorization Notice No. CN 103212020 B (application number 201310085695.3) discloses a kind of Chinese medicine composition for the treatment of functional dyspepsia, it is characterized in that: it is made up of the raw material of Chinese medicine of following weight proportion: Fructus Forsythiae 15g, Radix Bupleuri 12g, Herba Taraxaci 20g, Ramulus Cinnamomi 12g, rhizoma scirpi 10g, Rhizoma Curcumae 10g, Fructus Crataegi (parched) 15g, Massa Medicata Fermentata (parched) 15g, Fructus Hordei Germinatus (parched) 15g, Radix Aucklandiae 15g, Rhizoma Cyperi 12g, Endothelium Corneum Gigeriae Galli 10g, Semen Raphani 15g, Fructus Gardeniae 10g, Poria 15g, Cortex Magnoliae Officinalis 15g, Rhizoma Polygonati Odorati 15g.The Chinese patent literature of Authorization Notice No. CN 103285359 B (application number 201310242122.7) discloses a kind of medicine for the treatment of functional dyspepsia, this medicine is made up of active ingredient and medically acceptable excipient, and wherein said active ingredient is made up of the crude drug of following percentage by weight: Folium Perillae 20-35%, Rhizoma Cyperi 20-25%, Rhizoma Curcumae 15-20%, Rhizoma Coptidis 15-20% and Rhizoma Zingiberis 15-20%.
In a word, Chinese medicine achieves good curative effect in treatment primary disease, but also there are some problems: clinical also not for the medicine of spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels, having much room for improvement to improving the misery that functional dyspepsia brings.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, the traditional Chinese medicine thick paste of the easy treatment functional dyspepsia of clothes for a long time.This traditional Chinese medicine thick paste has spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels, and soothing the liver pathogenic fire purging, dampness are except full effect.
Technical scheme of the present invention is:
Treat a traditional Chinese medicine thick paste for functional dyspepsia, be prepared from by the primary raw material of following weight proportioning: Herba Erigerontis Annui 6-10 part, Radix Raphani 10-20 part, Rhizoma Dioscoreae esculentae 15-25 part, Fructus Hippophae 5-10 part, Fructus Crataegi 15-25 part, Rhizoma Cyperi 15-25 part, Rhizoma Pinelliae 15-23 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 18-24 part, Herba Dendrobii 9-16 part, Mel 10-20 part, Folium Eriobotryae 8-20 part, Herba Pogostemonis 12-20 part.
Treat a traditional Chinese medicine thick paste for functional dyspepsia, preferred scheme is, is prepared from by the primary raw material of following weight proportioning: Herba Erigerontis Annui 7-9 part, Radix Raphani 13-18 part, Rhizoma Dioscoreae esculentae 18-23 part, Fructus Hippophae 6-8 part, Fructus Crataegi 18-23 part, Rhizoma Cyperi 18-23 part, Rhizoma Pinelliae 18-20 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 19-21 part, Herba Dendrobii 12-14 part, Mel 13-18 part, Folium Eriobotryae 14-16 part, Herba Pogostemonis 14-18 part.
Treat a traditional Chinese medicine thick paste for functional dyspepsia, better preferred scheme is prepared from by the primary raw material of following weight proportioning: Herba Erigerontis Annui 8 parts, Radix Raphani 15 parts, Rhizoma Dioscoreae esculentae 20 parts, Fructus Hippophae 7 parts, Fructus Crataegi 20 parts, Rhizoma Cyperi 20 parts, the Rhizoma Pinelliae 19 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 20 parts, Herba Dendrobii 13 parts, Mel 15 parts, Folium Eriobotryae 15 parts, Herba Pogostemonis 16 parts.
According to the preparation method of the traditional Chinese medicine thick paste for the treatment of functional dyspepsia noted earlier, step is as follows:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 20-40 minute, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 30-40 DEG C, be placed in ventilation, after moisture drains, ultraviolet-sterilization 3-7 minute, be placed in non iron container, add the Chinese liquor sealing and standing 20-30 hour of 30-50 DEG C, filter, filtering residue is placed in and burns on hot iron plate, spread out even rear little fire to smoke 6-10 minute (preferably 8 minutes), cool, grind to form smalls, cross 120-160 mesh sieve (crossing 140 mesh sieves);
(3) first Folium Eriobotryae is placed in warm water to soak 30-40 minute (preferably soaking 35 minutes), adds Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after low baking temperature decocts 20-40 minute slowly on smokeless stove fire, big fire decocts 10-18 minute, filter, elimination filtering residue, filtrate is melted down again low baking temperature and is decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
Foregoing preparation method, preferred scheme is: step (1) water proof heating 25-35 minute (preferred, water proof heats 30 minutes).
Foregoing preparation method, preferred scheme is: step (2) after moisture drains, ultraviolet-sterilization 4-6 minute (preferred, after moisture drains, ultraviolet-sterilization 5 minutes).
Foregoing preparation method, preferred scheme is: step (2) adds Chinese liquor sealing and standing 23-28 hour (preferred, to add the Chinese liquor sealing and standing 25 hours of 40 DEG C) of 35-45 DEG C.
Foregoing preparation method, preferred scheme is: the consumption of step (2) Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 2-4 doubly (preferred, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 2.5-3.5 doubly, more preferably good, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 3 times).
Foregoing preparation method, preferred scheme is: step (3) low baking temperature on smokeless stove fire decocts (preferred, after low baking temperature decocts 30 minutes slowly on smokeless stove fire) after 25-35 minute slowly.
Foregoing preparation method, preferred scheme is: step (3) big fire decocts 12-16 minute (preferred, big fire decocts 14 minutes).
Using method: for making the present invention reach optimum therapeuticing effect, the traditional Chinese medicine thick paste be prepared from, gets 10-15 gram at every turn, is placed in clean bowl, warm water is washed open in sooner or later taking half an hour after the meal, within 5 days, is a course for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Erigerontis Annui: base is former: be the herb of Compositae Herba Erigerontis aceris platymiscium Herba Erigerontis Annui.Composition: herb is containing pyromeconic acid.Flower is containing pyrite constituents: Quercetin, apigenin-7-glucuronide, apigenin etc.The property of medicine: sweet, bitter, cold.Function cures mainly: removing toxic substances, and hemostasis, helps digestion, preventing the attack (or recurrence) of malaria.Cure mainly lymphadenitis, gingivitis, venom, hematuria, dyspepsia, gastroenteritis, malaria.
Radix Raphani: base is former: be fresh of Cruciferae Radix Raphani platymiscium Radix Raphani.Composition: root contains glycoside glucosinolate, glucose raphanin, raphanusin.Phenolic acids: P-coumaric acid, caffeic acid, ferulic acid, phenylpyruvic acid, gentisic acid etc.The property of medicine: acrid, sweet, cool; Ripe person is sweet, flat.Return spleen, stomach, lung, large intestine channel.Function cures mainly: help digestion, and the therapeutic method to keep the adverse QI flowing downwards is reduced phlegm, hemostasis.Cure mainly dyspepsia, food stagnation distension, acid regurgitation, regurgitation of food from the stomach, tells food, and hemorrhoidal hamorrhage is had loose bowels, dysentery, constipation, phlegm-heat cough, discomfort in the throat, hemoptysis, and spit blood, epistaxis, has blood in stool, and quenches one's thirst, and drenches worm.Outer treatment skin ulcer abscess, damage congestive edema, scalds and chilblain.
Rhizoma Dioscoreae esculentae: another name Zhu potato, Rhizoma Dioscoreae, Red Hill medicine, golden potato, sweet potato, Radix Pachyrhizi Erosi.Flavor efficacy is sweet, flat, nontoxic.Enter spleen, kidney channel.Function invigorating middle warmer and blood, supplementing QI for promoting the production of body fluid, wide the intestines and stomach, relieving constipation is secret.Be applicable to the dyspepsia caused by weakness of the spleen and stomach, have loose bowels, external can control carbuncle pyogenic infections from tumour or sore etc.
Fructus Hippophae: base is former: be the fruit of Elaeangnaceae hippophae plant Chinese sea buckthorn and yunnan seabuckthorn.Composition: sea buckthorn fruit is containing pyrite constituents: isorhamnetin, isorhamnetin-3-O-β-D-glycopranoside, rutin, astragalin and Quercetin and kaempferol are the low glucosides etc. of aglycon.The property of medicine: " Chinese herbal medicine is commonly used in Tibet ": " warm in nature, sour in the mouth, puckery." function cures mainly: relieving cough and resolving phlegm, invigorating the stomach and promoting digestion, promoting blood circulation to remove blood stasis.Cure mainly cough with copious phlegm, pulmonary abscess, dyspepsia, abdominal pain due to retention of food, stomachache, enteritis, amenorrhea, traumatic injury congestive edema.
Fructus Crataegi: nature and flavor: sour, sweet, tepor.Gui Jing: return spleen, stomach, Liver Channel.Effect: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.Curing mainly: for meat stagnation. gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation. trusted subordinate's twinge. hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation. dysentery is not well.
Rhizoma Cyperi: nature and flavor: pungent, micro-hardship, micro-sweet, flat.Gui Jing: return liver, spleen, tri-jiao channel.Effect: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.Cure mainly: for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
The Rhizoma Pinelliae: nature and flavor: pungent, warm; Poisonous, Gui Jing: return spleen, stomach, lung meridian.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Cure mainly: for abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and thymus painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Hericium erinaceus (Bull. Ex Fr.) Pers.: base is former: be the sporophore of hedgehog fungus section Hericium fungus Hericium erinaceus (Bull. Ex Fr.) Pers., Hydnum.Composition: containing Hericium erinaceus (Bull. Ex Fr.) Pers. Ketone A, B, C, D, E, F, G, H in Hericium erinaceus, Hericium erinaceus (Bull. Ex Fr.) Pers. alkali etc.Dry sporophore is containing protein, lipid, fiber and glucosan.Also containing sterols: ergosterol etc.Mycelium culture contains Hericium erinaceus (Bull. Ex Fr.) Pers. pyrone A, B etc.The property of medicine: " national Chinese herbal medicine compilation ": " sweet, flat." function cures mainly: strengthening the spleen and nourishing the stomach, calms the nerves, anticancer.Cure mainly body void weak, dyspepsia, insomnia, gastroduodenal ulcer, chronic gastritis, digestive tract tumor.
Herba Dendrobii: nature and flavor: sweet, is slightly cold.Gui Jing: return stomach, kidney channel.Effect: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Cure mainly: lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched. deficiency-heat after being ill. and poor vision.
Mel: another name: SHIMI, stone maltosemalt sugar, Mel, Mel, husky honey.Mel is a kind of nutritious natural nourishing food, is also one of the most frequently used tonic.According to analysis, containing the trace element with the multiple organic acid such as the plurality of inorganic salt of human serum concentration comparable and vitamin, ferrum, calcium, copper, manganese, potassium, phosphorus and useful health, and fructose, glucose, amylase, oxidase, reductase etc., there is nourishing, moisturize, detoxify, effect of beauty face-whitening-nourishing, loosening bowel to relieve constipation.
Folium Eriobotryae: nature and flavor: bitter, is slightly cold.Gui Jing: attach to the lung and stomach meridians.Effect: clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.Curing mainly: for cough due to lung-heat. QI rising in reverse order is panted, and gastric heat vomiting, dysphoria with smothery sensation is thirsty.
Herba Pogostemonis: nature and flavor: pungent, tepor.Gui Jing: return spleen, stomach, lung meridian.Effect: eliminating turbid pathogen with aromatics, appetizing preventing or arresting vomiting, delivers expelling summer-heat.Cure mainly: for turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is vomitted, and heat-damp in summer asthenia is not uncomfortable in chestly relaxed, and cold-damp closes summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Traditional Chinese medicine thick paste scientific formula provided by the invention, the preparation method of dosage form is simple, products obtained therefrom taking convenience, is easy to carry, and in addition, excellent results of the present invention also shows:
1, selected materials is all Chinese medicine material, spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels will be had, the crude drug that soothing the liver pathogenic fire purging, dampness remove full effect is combined, through special processing technique be prepared from without any side effects, can spleen invigorating warming middle-JIAO, soothing the liver pathogenic fire purging, the sanguimotor thick paste of intestinal can be improved again;
2, this prescription meets patient's body and mind feature of Chinese medicine principle and functional dyspepsia completely, under the prerequisite of general principle, can have different prescription according to different crowd, and function is different.
3, medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
Embodiment 1 one kinds treats the traditional Chinese medicine thick paste of functional dyspepsia, gets the raw materials ready (getting 10g for every part): Herba Erigerontis Annui 6 parts by following weight parts, Radix Raphani 10 parts, Rhizoma Dioscoreae esculentae 15 parts, Fructus Hippophae 5 parts, Fructus Crataegi 15 parts, Rhizoma Cyperi 15 parts, the Rhizoma Pinelliae 15 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 18 parts, Herba Dendrobii 9 parts, Mel 10 parts, Folium Eriobotryae 8 parts, Herba Pogostemonis 12 parts.
The preparation method of the traditional Chinese medicine thick paste of above-mentioned treatment functional dyspepsia:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 20 minutes, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 30 DEG C, ventilation is placed in, after moisture drains, ultraviolet-sterilization 3 minutes, be placed in non iron container, add the Chinese liquor sealing and standing 20 hours of 30 DEG C, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 2 times, filter, filtering residue is placed in and burns on hot iron plate, spreads out even rear little fire and smokes 6 minutes, cool, grind to form smalls, cross 120 mesh sieves;
(3) first Folium Eriobotryae is placed in warm water to soak 30 minutes, adding Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after on smokeless stove fire, low baking temperature decocts 20 minutes slowly, big fire decocts 10 minutes, filters, elimination filtering residue, and filtrate is melted down again low baking temperature and decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
Typical case one: Wu XX, female 30 years old, Heze City, Shandong Province personage, cadre at their posts.Last year is because of traffic accident rupture of spleen, enterorrhexis operative treatment, perform the operation very well, without exception when leaving hospital, after 1 year, patient is because of eating and drinking without temperance sense paroxysmal abdominal pain, nausea and vomiting, abdominal tympanites, not defecation also not aerofluxus, dare not have a meal more, but hunger again very, Sui Qu hospital checks, doctor, by going the inquiry of patient and being diagnosed as functional dyspepsia in conjunction with medical history, takes thick paste of the present invention.
Take the embodiment of the present invention 1 gained traditional Chinese medicine thick paste, after 1 course for the treatment of, patient's sensation is so inviolent in pain, does not have the symptoms such as Nausea and vomiting yet, after continuing to take 2 courses for the treatment of, basic malaise symptoms disappears, and the state of an illness is basicly stable, continue to take to do 1 course for the treatment of and consolidate, without recurrence after drug withdrawal.
Embodiment 2 one kinds treats the traditional Chinese medicine thick paste of functional dyspepsia, gets the raw materials ready (getting 10g for every part): Herba Erigerontis Annui 10 parts by following weight parts, Radix Raphani 20 parts, Rhizoma Dioscoreae esculentae 25 parts, Fructus Hippophae 10 parts, Fructus Crataegi 25 parts, Rhizoma Cyperi 25 parts, the Rhizoma Pinelliae 23 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 24 parts, Herba Dendrobii 16 parts, Mel 20 parts, Folium Eriobotryae 20 parts, Herba Pogostemonis 20 parts.
The preparation method of the traditional Chinese medicine thick paste of above-mentioned treatment functional dyspepsia is:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 40 minutes, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 40 DEG C, ventilation is placed in, after moisture drains, ultraviolet-sterilization 7 minutes, be placed in non iron container, add the Chinese liquor sealing and standing 30 hours of 50 DEG C, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 4 times, filter, filtering residue is placed in and burns on hot iron plate, spreads out even rear little fire and smokes 10 minutes, cool, grind to form smalls, cross 160 mesh sieves;
(3) first Folium Eriobotryae is placed in warm water to soak 40 minutes, adding Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after on smokeless stove fire, low baking temperature decocts 40 minutes slowly, big fire decocts 18 minutes, filters, elimination filtering residue, and filtrate is melted down again low baking temperature and decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
Typical case two: Lee XX, man 38 years old.Henan Zhumadian personage, before 2 months, there is the abdominal distention of unknown cause in certain high school teachers, the symptoms such as stomachache, originally think and oneself eaten thing bad, bought JIANWEI XIAOSHI PIAN voluntarily and taken, effective when taking at the beginning, serious all the more after drug withdrawal, have also appeared not eating, distension after food, stomach has the malaise symptoms of burning sensation, patient does not like Western medicine, and doctor advised takes gained traditional Chinese medicine thick paste of the present invention.
Give the oral embodiment of the present invention 2 and obtain thick paste, after 1 course for the treatment of, the symptom of patient's self-induction abdominal distention, stomachache alleviates to some extent, and after continuing to have taken 2 courses for the treatment of, malaise symptoms disappears substantially, continues again to take 1 course for the treatment of, cures completely, not showing effect more so far 1 year.
Embodiment 3 one kinds treats the traditional Chinese medicine thick paste of functional dyspepsia, gets the raw materials ready (getting 10g for every part): Herba Erigerontis Annui 7 parts by following weight parts, Radix Raphani 13 parts, Rhizoma Dioscoreae esculentae 18 parts, Fructus Hippophae 6 parts, Fructus Crataegi 18 parts, Rhizoma Cyperi 18 parts, the Rhizoma Pinelliae 18 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 19 parts, Herba Dendrobii 12 parts, Mel 13 parts, Folium Eriobotryae 14 parts, Herba Pogostemonis 14 parts.
The preparation method of the traditional Chinese medicine thick paste of above-mentioned treatment functional dyspepsia is:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 25 minutes, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 33 DEG C, ventilation is placed in, after moisture drains, ultraviolet-sterilization 4 minutes, be placed in non iron container, add the Chinese liquor sealing and standing 23 hours of 35 DEG C, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 2.5 times, filter, filtering residue is placed in and burns on hot iron plate, spreads out even rear little fire and smokes 7 minutes, cool, grind to form smalls, cross 130 mesh sieves;
(3) first Folium Eriobotryae is placed in warm water to soak 33 minutes, adding Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after on smokeless stove fire, low baking temperature decocts 25 minutes slowly, big fire decocts 12 minutes, filters, elimination filtering residue, and filtrate is melted down again low baking temperature and decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
Typical case three: Zou XX, female, 40 years old, Jinan, Shandong Province personage, the workman of certain factory, because of paroxysmal abdominal pain abdominal distention before 3 months, non-defecation aerofluxus was admitted to hospital for 3 days.When doctor makes the rounds of the wards, patient's readme is stomach distending pain after meal, has heartburn, acid regurgitation sense, constipation, and doctor advised takes traditional Chinese medicine thick paste of the present invention.
Take 2 courses for the treatment of of the embodiment of the present invention 3 gained traditional Chinese medicine thick paste, after conscious medicine, abdominal distention, gastral cavilty distension slightly alleviate, and do not occur heartburn, acid regurgitation, arteries and veins slight force; Continue and take 1 course for the treatment of, abdominal distention, gastral cavilty distension are not obvious; Diet increases, comfortable in stomach after food; Stool is once a day, not dry not rare; Without singultus, heartburn, acid regurgitation symptom; Consolidate and take 1 course for the treatment of, transference cure, appetite increases, energetic.
Embodiment 4 one kinds treats the traditional Chinese medicine thick paste of functional dyspepsia, gets the raw materials ready (getting 10g for every part): Herba Erigerontis Annui 9 parts by following weight parts, Radix Raphani 18 parts, Rhizoma Dioscoreae esculentae 23 parts, Fructus Hippophae 8 parts, Fructus Crataegi 23 parts, Rhizoma Cyperi 23 parts, the Rhizoma Pinelliae 20 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 21 parts, Herba Dendrobii 14 parts, Mel 18 parts, Folium Eriobotryae 16 parts, Herba Pogostemonis 18 parts.
The preparation method of the traditional Chinese medicine thick paste of above-mentioned treatment functional dyspepsia is:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 35 minutes, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 38 DEG C, ventilation is placed in, after moisture drains, ultraviolet-sterilization 6 minutes, be placed in non iron container, add the Chinese liquor sealing and standing 28 hours of 45 DEG C, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 3.5 times, filter, filtering residue is placed in and burns on hot iron plate, spreads out even rear little fire and smokes 9 minutes, cool, grind to form smalls, cross 150 mesh sieves;
(3) first Folium Eriobotryae is placed in warm water to soak 38 minutes, adding Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after on smokeless stove fire, low baking temperature decocts 35 minutes slowly, big fire decocts 16 minutes, filters, elimination filtering residue, and filtrate is melted down again low baking temperature and decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
Embodiment 5 one kinds treats the traditional Chinese medicine thick paste of functional dyspepsia, gets the raw materials ready (getting 10g for every part): Herba Erigerontis Annui 8 parts by following weight parts, Radix Raphani 15 parts, Rhizoma Dioscoreae esculentae 20 parts, Fructus Hippophae 7 parts, Fructus Crataegi 20 parts, Rhizoma Cyperi 20 parts, the Rhizoma Pinelliae 19 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 20 parts, Herba Dendrobii 13 parts, Mel 15 parts, Folium Eriobotryae 15 parts, Herba Pogostemonis 16 parts.
The preparation method of the traditional Chinese medicine thick paste of above-mentioned treatment functional dyspepsia is:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 30 minutes, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 35 DEG C, ventilation is placed in, after moisture drains, ultraviolet-sterilization 5 minutes, be placed in non iron container, add the Chinese liquor sealing and standing 25 hours of 40 DEG C, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 3 times, filter, filtering residue is placed in and burns on hot iron plate, spreads out even rear little fire and smokes 8 minutes, cool, grind to form smalls, cross 140 mesh sieves;
(3) first Folium Eriobotryae is placed in warm water to soak 35 minutes, adding Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after on smokeless stove fire, low baking temperature decocts 30 minutes slowly, big fire decocts 14 minutes, filters, elimination filtering residue, and filtrate is melted down again low baking temperature and decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
The clinical practice of the traditional Chinese medicine thick paste of test example 1 embodiment 5 gained treatment functional dyspepsia: screen 400 routine patients in 10 hospitals, wherein women 200 example, male 200 example.Before test 2 weeks, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, and matched group takes medicine conventional medication such as () Renshenjianpi Tablet, Zhizhukuanzhong capsule, lenitive pill and Fuzi Lizhong Wans of other treatment functional dyspepsia.Using method is: for making the present invention reach optimum therapeuticing effect, the traditional Chinese medicine thick paste be prepared from, gets 10-15 gram at every turn, is placed in clean bowl, and warm water is washed open in sooner or later taking half an hour after the meal, within 5 days, is a course for the treatment of.Curative effect situation criterion: cure: after taking this product, malaise symptoms disappears; Effective: after taking this product, malaise symptoms makes moderate progress; Invalid: after taking this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take this product treatment patients with functional dyspepsia therapeutic outcome
Therapeutic effect: cure 198 examples (99%), exceed 19% than matched group cure rate, the 1st time obvious effective rate exceeds 46%, and successful is better than matched group.
Take this product 3 days, more than 67% feel takes a turn for the better to some extent, and malaise symptoms improves, and the malaise symptoms such as upper abdominal pain, big belly, early full, belch, inappetence, Nausea and vomiting alleviate to some extent; Take 5 days, more than 75% feel takes a turn for the better to some extent, and malaise symptoms improves or disappears, and the malaise symptoms such as abdominal distention obviously improve; Take 10 days, the self-induction recovery from illness of more than 97%, malaise symptoms disappears.Take more than 5 days in experimental group, effective percentage can reach 99%, and matched group is only 80%.The present invention has effect of spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels, reducing swelling and alleviating pain, hard masses softening and resolving, eliminating blood stasis and inducing menstruation, and enterobacteria can be suppressed to grow, finally reach and promote aerofluxus, defecation, anti-inflammation detumescence, alleviate abdominal distention stomachache, recover the effect of gastrointestinal function, remarkable through clinical proof clinical efficacy of the present invention, easy to use, economy, safety, patient compliance is high, and clinic is promoted.
Claims (10)
1. treat a traditional Chinese medicine thick paste for functional dyspepsia, it is characterized in that: be prepared from by the primary raw material of following weight proportioning: Herba Erigerontis Annui 6-10 part, Radix Raphani 10-20 part, Rhizoma Dioscoreae esculentae 15-25 part, Fructus Hippophae 5-10 part, Fructus Crataegi 15-25 part, Rhizoma Cyperi 15-25 part, Rhizoma Pinelliae 15-23 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 18-24 part, Herba Dendrobii 9-16 part, Mel 10-20 part, Folium Eriobotryae 8-20 part, Herba Pogostemonis 12-20 part.
2. the traditional Chinese medicine thick paste for the treatment of functional dyspepsia according to claim 1, is characterized in that, is prepared from by the primary raw material of following weight proportioning: Herba Erigerontis Annui 7-9 part, Radix Raphani 13-18 part, Rhizoma Dioscoreae esculentae 18-23 part, Fructus Hippophae 6-8 part, Fructus Crataegi 18-23 part, Rhizoma Cyperi 18-23 part, Rhizoma Pinelliae 18-20 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 19-21 part, Herba Dendrobii 12-14 part, Mel 13-18 part, Folium Eriobotryae 14-16 part, Herba Pogostemonis 14-18 part.
3. the traditional Chinese medicine thick paste for the treatment of functional dyspepsia according to claim 1, is characterized in that, is prepared from by the primary raw material of following weight proportioning: Herba Erigerontis Annui 8 parts, Radix Raphani 15 parts, Rhizoma Dioscoreae esculentae 20 parts, Fructus Hippophae 7 parts, Fructus Crataegi 20 parts, Rhizoma Cyperi 20 parts, the Rhizoma Pinelliae 19 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 20 parts, Herba Dendrobii 13 parts, Mel 15 parts, Folium Eriobotryae 15 parts, Herba Pogostemonis 16 parts.
4. the preparation method of the traditional Chinese medicine thick paste of the treatment functional dyspepsia according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Radix Raphani, Rhizoma Dioscoreae esculentae are cleaned the Fructus Crataegi of removing the peel block and the enucleation of being cut into as Fructus Crataegi size to mix, be together placed in appropriate vessel, water proof heats 20-40 minute, and taking-up cools, stand-by with the rolling pin thing that mashes;
(2) by Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and the Herba Dendrobii warm water cleaning with 30-40 DEG C, be placed in ventilation, after moisture drains, ultraviolet-sterilization 3-7 minute, be placed in non iron container, add the Chinese liquor sealing and standing 20-30 hour of 30-50 DEG C, filter, filtering residue is placed in and burns on hot iron plate, spread out even rear little fire to smoke 6-10 minute (preferably 8 minutes), cool, grind to form smalls, cross 120-160 mesh sieve (crossing 140 mesh sieves);
(3) first Folium Eriobotryae is placed in warm water to soak 30-40 minute (preferably soaking 35 minutes), adds Hericium erinaceus (Bull. Ex Fr.) Pers. and Herba Pogostemonis, after low baking temperature decocts 20-40 minute slowly on smokeless stove fire, big fire decocts 10-18 minute, filter, elimination filtering residue, filtrate is melted down again low baking temperature and is decocted;
(4) step (1) gained pastel and step (2) gained smalls are together added in the filtrate that step (3) low baking temperature decocts; decoct while stir with waddy; to be mixed evenly after; add Mel; melt completely at the secondary Mel that is stirred to, cover lid, cease fire; when cooling to room temperature, bottle and obtain traditional Chinese medicine thick paste.
5. preparation method according to claim 4, is characterized in that: step (1) water proof heating 25-35 minute (preferred, water proof heats 30 minutes).
6. preparation method according to claim 4, is characterized in that: step (2) after moisture drains, ultraviolet-sterilization 4-6 minute (preferred, after moisture drains, ultraviolet-sterilization 5 minutes).
7. preparation method according to claim 4, is characterized in that: step (2) adds Chinese liquor sealing and standing 23-28 hour (preferred, to add the Chinese liquor sealing and standing 25 hours of 40 DEG C) of 35-45 DEG C.
8. preparation method according to claim 4, it is characterized in that: the consumption of step (2) Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 2-4 doubly (preferred, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 2.5-3.5 doubly, more preferably good, the consumption of Chinese liquor be Herba Erigerontis Annui, Fructus Hippophae, Rhizoma Cyperi, the Rhizoma Pinelliae and Herba Dendrobii consumption 3 times).
9. preparation method according to claim 4, is characterized in that: step (3) low baking temperature on smokeless stove fire decocts (preferred, after low baking temperature decocts 30 minutes slowly on smokeless stove fire) after 25-35 minute slowly.
10. preparation method according to claim 4, is characterized in that: step (3) big fire decocts 12-16 minute (preferred, big fire decocts 14 minutes).
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Application publication date: 20150325 |