CN1336218A - Prepn. of wetness-evil eliminating and dyspepsia relieving medicine tablet - Google Patents

Prepn. of wetness-evil eliminating and dyspepsia relieving medicine tablet Download PDF

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Publication number
CN1336218A
CN1336218A CN 01127775 CN01127775A CN1336218A CN 1336218 A CN1336218 A CN 1336218A CN 01127775 CN01127775 CN 01127775 CN 01127775 A CN01127775 A CN 01127775A CN 1336218 A CN1336218 A CN 1336218A
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Prior art keywords
radix
fructus
rhizoma
semen
volatile oil
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CN 01127775
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CN1136902C (en
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张京维
熊国运
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Guangdong Kelun Pharmaceutical Co Ltd
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GUANGDONG QINGFA PHARMACEUTICAL INDUSTRY Co Ltd
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Publication of CN1336218A publication Critical patent/CN1336218A/en
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Publication of CN1136902C publication Critical patent/CN1136902C/en
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Abstract

The present invention relates to preparation method of medicinal tablet for eliminating wetness-evil and relieving dyspepsia. With two times of water being added to a mixture of ligusticum root, radix aucklandiae, rhizoma atractylodis, perillae, dried orange, fructus aurantii immaturus, herba agastachis and steamed, the volatile oil is obtained by distillation. With water being added to 12 traditional Chinese medicinal herbs including radix bulpleuri, radix platycodi etc and above mentioned dreg, and decocted twice, filtered filtrated, concentrated at last the paste is obtained. With malt, fructus amomi, medicaled leaven being ground into powder, mixing the powder into said paste forms particles, spraying the particles with said volatile oil and pressing it obtains the tablet.

Description

The preparation method of wetness-evil eliminating and dyspepsia relieving medicine tablet
The present invention relates to the preparation method of a kind of preparation of medicine, particularly a kind of wetness-evil eliminating and dyspepsia relieving medicine tablet.
Turbid damp retardance, eating accumulation are class common diseases in digestive system, and disease is seen dyspepsia, distension and fullness in the abdomen, pain, diarrhea with loose stool.Often adopt the removing dampness method stagnant, relieving dyspepsia that disappears to carry out clinically.At present the Chinese patent medicine commonly used of this type of disease of treatment is more, these Chinese patent medicines on effect, have based on intestinal stasis relieving, have based on removing dampness, what have then lays particular emphasis on circulation of qi promoting, and clinically often retention of damp leading to blockage of QI food stagnation etc. disease is double sees, and with insufficiency of the spleen relevant, these Chinese patent medicines but fail to adapt to this characteristics; On the preparation process, also have some shortcomings, full powder pill person has taking dose excessive, the fraud of delayed action, and the decocting boiling down contraction person of one-tenth then easily makes the volatile ingredient loss, influences drug effect.
Purpose of the present invention just provide a kind ofly have circulation of qi promoting, removing dampness, the preparation method of the wetness-evil eliminating and dyspepsia relieving medicine tablet of stagnant, the spleen invigorating of disappearing.
The tablet that the present invention is made by following materials of weight proportions:
Fructus Hordei Germinatus 5~8 Semen Raphanis 8~10 fructus amomis 5~8 Radix Bupleuri 10~12
Semen Arecae 15~18 Rhizoma Atractylodis (parched) 5~8 Fructus Crataegis 10~12 Poria 8~10
Radix Platycodonis 5~8 Pericarpium Citri Reticulataes 8~10 Semen Lablab Albums 8~10 Folium Perillaes 10~12
The Radix Aucklandiae 5~8 Cortex Magnoliae Officinalis 5~8 Rhizoma Cyperis 8~10 Radix Scutellariaes 5~8
Rhizoma Chuanxiong 5~8 Massa Medicata Fermentata 8~10 Fructus Aurantii Immaturuss 10~12 Herba Pogostemoniss 8~10
Radix Puerariae 10~12 Rhizoma Pinelliae Preparata 10~12
The present invention prepares by the following method: get Rhizoma Chuanxiong, the Radix Aucklandiae, Rhizoma Atractylodis (parched), Folium Perillae, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Herba Pogostemonis seven flavors, add 2 times of water gagings, extract volatile oil with steam distillation; Get Semen Arecae, Cortex Magnoliae Officinalis, Fructus Crataegi, Radix Bupleuri, Rhizoma Cyperi, Radix Platycodonis, Radix Puerariae, Radix Scutellariae, Rhizoma Pinelliae Preparata, Poria, Semen Raphani, Semen Lablab Album 12 flavors and above-mentioned medicinal residues and add water, decoct 2 times, each 1.5 hours, filter, merging filtrate is condensed into fluid extract; Get Fructus Hordei Germinatus, Massa Medicata Fermentata, fructus amomi three flavors and be ground into fine powder, be added in the fluid extract, mixing adds excipient and makes granule, behind the dry granulate, sprays volatile oil, tabletting.
The present invention is according to disease, according to the theory of Chinese medical science prescription, makes it to have circulation of qi promoting, removing dampness, effect stagnant, spleen invigorating disappears.Rhizoma Chuanxiong, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Rhizoma Cyperi, fructus amomi have the effect that circulation of qi promoting is regulated the flow of vital energy, Rhizoma Atractylodis (parched), Radix Scutellariae, Poria, Herba Pogostemonis, Rhizoma Pinelliae Preparata, Semen Lablab Album have the effect of removing dampness, Fructus Hordei Germinatus, Fructus Crataegi, Massa Medicata Fermentata, Semen Raphani, Semen Arecae can be controlled all kinds of eating accumulations, and Semen Lablab Album, Rhizoma Atractylodis (parched), fructus amomi also have the effect of spleen invigorating warming the spleen.Among the present invention, all medicine prescriptions, both contained Rhizoma Chuanxiong compatibility Rhizoma Cyperi, Rhizoma Atractylodis (parched), Massa Medicata Fermentata etc. and played the justice of promote qi circulation digestion promoting dampness altogether, had again that the merit of drying damp and strengthening spleen Pingwei San such as Cortex Magnoliae Officinalis compatibility Rhizoma Atractylodis, Pericarpium Citri Reticulatae and Semen Raphani compatibility Fructus Crataegi, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparata, Fructus Hordei Germinatus, Poria, Massa Medicata Fermentata etc. help digestion, the effect of the lenitive pill of intestinal stasis relieving stomach function regulating with the Yueju Wan of relieving stagnation.Simultaneously, also stopping leak rushes down with the gas of the clear sun of a Radix Puerariae liter taste in the present invention; Its property liter of Radix Bupleuri and loosing adds it among the present invention, is because of " yang-energy sink, and then gathers for diet, and sun rises then that clearing heat in QI system rises, the capable Yang Dao of QI of the spleen and stomach, then diet gathers from dissipation " (" Bencao Jingshu ").Radix Platycodonis is gone into lung meridian, and it is logical that opening lung-energy, lung being connected with large intestine, lung qi are opened then internal organs gas, adds it among the present invention, can alleviate stomachache, " Mingyi Bielu " cloud, Radix Platycodonis " the rapid digestion of food person rises with it and to carry a yang-energy, makes Jiao placed in the middle and does not sink, and then yang-energy is long floating, and the paddy food is from disappearing ".
The present invention on the preparation process according to the different of the contained composition of each herbal medicine and in prescription role adopt different extracting method.Rhizoma Chuanxiong, the Radix Aucklandiae, Rhizoma Atractylodis (parched), Folium Perillae, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Herba Pogostemonis seven flavors contain the volatile oil active ingredient, adopt steam distillation to extract volatile oil earlier, spray volatile oil after making granule again, save the unlikely volatilization ease of volatile oil from damage and lose.For the active ingredient that makes this class medicine is extracted more fully, its medicinal residues and decocting medicine are with frying in shallow oil.Digestive enzyme such as the starch-containing enzyme of Fructus Hordei Germinatus, Massa Medicata Fermentata are contained the medicine that yeast and fructus amomi contain thermo-labile compositions such as armaticity composition then it is ground into fine powder, directly add and make the granule tabletting in the fluid extract.
The present invention has circulation of qi promoting, removing dampness, the effect stagnant, spleen invigorating that disappears, and is used for that dyspepsia, stomachache are had loose bowels, infantile malnutrition, anorexia and loose stool etc.
Below in conjunction with embodiment, the invention will be further described.
Fig. 1 is a flow chart of the present invention.
Take by weighing raw material (kilogram) by following proportioning:
Fructus Hordei Germinatus 5 Semen Raphanis 8 fructus amomis 5 Radix Bupleuri 10
Semen Arecae 15 Rhizoma Atractylodis (parched) 7 Fructus Crataegis 10 Poria 8
Radix Platycodonis 8 Pericarpium Citri Reticulataes 8 Semen Lablab Albums 10 Folium Perillaes 12
The Radix Aucklandiae 5 Cortex Magnoliae Officinalis 5 Rhizoma Cyperis 8 Radix Scutellariaes 5
Rhizoma Chuanxiong 5 Massa Medicata Fermentata 8 Fructus Aurantii Immaturuss 10 Herba Pogostemoniss 10
Radix Puerariae 12 Rhizoma Pinelliae Preparata 12
Production method is as follows: get Rhizoma Chuanxiong, the Radix Aucklandiae, Rhizoma Atractylodis (parched), Folium Perillae, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Herba Pogostemonis seven flavors, add 186Kg water, place multi-functional extractor, extract volatile oil with steam distillation, 4 hours time; Getting Semen Arecae, Cortex Magnoliae Officinalis, Fructus Crataegi, Radix Bupleuri, Rhizoma Cyperi, Radix Platycodonis, Radix Puerariae, Radix Scutellariae, system half tall building, Poria, Semen Raphani, Semen Lablab Album 12 flavors and above-mentioned medicinal residues, to add water an amount of, decocts 2 times, and each 1.5 hours, filtration, merging filtrate is condensed into fluid extract; Get Fructus Hordei Germinatus, Massa Medicata Fermentata, fructus amomi three flavors and be ground into fine powder with pulverizer, be added in the fluid extract, mixing adds gelatinized corn starch and makes granule, behind the dry granulate, sprays volatile oil, and tabletting is made 300000.

Claims (2)

1. wetness-evil eliminating and dyspepsia relieving medicine tablet is characterized in that the tablet of being made by following materials of weight proportions:
Fructus Hordei Germinatus 5~8 Semen Raphanis 8~10 fructus amomis 5~8 Radix Bupleuri 10~12
Semen Arecae 15~18 Rhizoma Atractylodis (parched) 5~8 Fructus Crataegis 10~12 Poria 8~10
Radix Platycodonis 5~8 Pericarpium Citri Reticulataes 8~10 Semen Lablab Albums 8~10 Folium Perillaes 10~12
The Radix Aucklandiae 5~8 Cortex Magnoliae Officinalis 5~8 Rhizoma Cyperis 8~10 Radix Scutellariaes 5~8
Rhizoma Chuanxiong 5~8 Massa Medicata Fermentata 8~10 Fructus Aurantii Immaturuss 10~12 Herba Pogostemoniss 8~10
Radix Puerariae 10~12 Rhizoma Pinelliae Preparata 10~12
2. according to the preparation method of the described wetness-evil eliminating and dyspepsia relieving medicine tablet of claim 1, it is characterized in that:
(1) gets Rhizoma Chuanxiong, the Radix Aucklandiae, Rhizoma Atractylodis (parched), Folium Perillae, Pericarpium Citri Reticulatae, Fructus Aurantii Immaturus, Herba Pogostemonis seven flavors, add 2 times of water gagings, extract volatile oil with steam distillation;
(2) get Semen Arecae, Cortex Magnoliae Officinalis, Fructus Crataegi, Radix Bupleuri, Rhizoma Cyperi, Radix Platycodonis, Radix Puerariae, Radix Scutellariae, Rhizoma Pinelliae Preparata, Poria, Semen Raphani, Semen Lablab Album 12 flavors and above-mentioned medicinal residues and add water, decoct 2 times, each 1.5 hours, filter, merging filtrate is condensed into fluid extract;
(3) get Fructus Hordei Germinatus, Massa Medicata Fermentata, fructus amomi three flavors and be ground into fine powder, be added in the fluid extract, mixing adds excipient and makes granule, behind the dry granulate, sprays volatile oil, tabletting.
CNB011277750A 2001-08-21 2001-08-21 Prepn. of wetness-evil eliminating and dyspepsia relieving medicine tablet Expired - Fee Related CN1136902C (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100381158C (en) * 2005-12-29 2008-04-16 颜怀伟 Medicine and food dual purpose Chinese medicine for reinforcing digestion and its manufacturing method
CN101152530B (en) * 2007-09-19 2010-06-02 牛海艳 Method for preparing defervesce and promoting digestion capsule for children
CN103330926A (en) * 2013-06-27 2013-10-02 温兴韬 Toxin-expelling and uarthritis-resisting medicine
CN103721128A (en) * 2013-12-27 2014-04-16 廖勇 Traditional Chinese medicinal composition for treating infantile malnutrition and preparation method thereof
CN103784927A (en) * 2014-02-24 2014-05-14 安徽科技学院 Traditional Chinese medicinal drinking water preparation for resisting stress reaction of livestock and poultry during transportation
CN103861015A (en) * 2014-03-31 2014-06-18 袁志贤 Traditional Chinese medicine for treating chronic enteritis and preparation method thereof
CN103877483A (en) * 2014-03-31 2014-06-25 袁志贤 Traditional Chinese medicine for treating chronic gastritis and preparation method thereof
CN104338062A (en) * 2014-10-30 2015-02-11 崔银方 Chinese medicinal preparation for treating stomachache and diarrhea
CN104435744A (en) * 2014-10-09 2015-03-25 黄珊 Traditional Chinese medicine thick paste for treating functional dyspepsia and preparation method of traditional Chinese medicine thick paste
WO2015149390A1 (en) * 2014-03-31 2015-10-08 袁志贤 Traditional chinese medicine oral liquid for treating chronic enteritis and preparation method therefor

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100381158C (en) * 2005-12-29 2008-04-16 颜怀伟 Medicine and food dual purpose Chinese medicine for reinforcing digestion and its manufacturing method
CN101152530B (en) * 2007-09-19 2010-06-02 牛海艳 Method for preparing defervesce and promoting digestion capsule for children
CN103330926A (en) * 2013-06-27 2013-10-02 温兴韬 Toxin-expelling and uarthritis-resisting medicine
CN103330926B (en) * 2013-06-27 2015-08-19 温兴韬 The spirit of toxin expelling gout
CN103721128A (en) * 2013-12-27 2014-04-16 廖勇 Traditional Chinese medicinal composition for treating infantile malnutrition and preparation method thereof
CN103784927A (en) * 2014-02-24 2014-05-14 安徽科技学院 Traditional Chinese medicinal drinking water preparation for resisting stress reaction of livestock and poultry during transportation
CN103784927B (en) * 2014-02-24 2016-05-11 安徽科技学院 A kind of Chinese medicine drinking agent of anti-livestock and poultry transport stress reaction
CN103861015A (en) * 2014-03-31 2014-06-18 袁志贤 Traditional Chinese medicine for treating chronic enteritis and preparation method thereof
CN103877483A (en) * 2014-03-31 2014-06-25 袁志贤 Traditional Chinese medicine for treating chronic gastritis and preparation method thereof
WO2015149390A1 (en) * 2014-03-31 2015-10-08 袁志贤 Traditional chinese medicine oral liquid for treating chronic enteritis and preparation method therefor
CN104435744A (en) * 2014-10-09 2015-03-25 黄珊 Traditional Chinese medicine thick paste for treating functional dyspepsia and preparation method of traditional Chinese medicine thick paste
CN104338062A (en) * 2014-10-30 2015-02-11 崔银方 Chinese medicinal preparation for treating stomachache and diarrhea

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C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Yazhou Pharmaceutical Co., Ltd., Dongguan City

Assignor: Guangdong Qingfa Pharmaceutical Industry Co., Ltd.

Contract fulfillment period: 2007.2.13 to 2012.2.12

Contract record no.: 2009440000992

Denomination of invention: Prepn. of wetness-evil eliminating and dyspepsia relieving medicine tablet

Granted publication date: 20040204

License type: Exclusive license

Record date: 20090731

LIC Patent licence contract for exploitation submitted for record

Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2007.2.13 TO 2012.2.12; CHANGE OF CONTRACT

Name of requester: DONGGUAN CITY ASIA PHARMACEUTICAL CO., LTD.

Effective date: 20090731

C56 Change in the name or address of the patentee

Owner name: GUANGDONG KELUN PHARMACEUTICAL CO., LTD.

Free format text: FORMER NAME: GUANGDONG QINGFA PHARMACEUTICAL INDUSTRY CO., LTD.

CP01 Change in the name or title of a patent holder

Address after: 514031, on the west side of Ring Road, Meizhou, Guangdong

Patentee after: GUANGDONG KELUN PHARMACEUTICAL CO., LTD.

Address before: 514031, on the west side of Ring Road, Meizhou, Guangdong

Patentee before: Guangdong Qingfa Pharmaceutical Industry Co., Ltd.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20040204

Termination date: 20190821