CN103877483A - Traditional Chinese medicine for treating chronic gastritis and preparation method thereof - Google Patents
Traditional Chinese medicine for treating chronic gastritis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating chronic gastritis and a preparation method thereof. The preparation disclosed by the invention is a composition liquid preparation which is prepared by the following steps: smashing, decocting, ethanol-extracting and mixing pogostemon cablin, folia perillae acutae, rhizoma atractylodis macrocephalae, pericarpium arecae, guergana guermanoff, rhizoma atractylodis, tribulusterrestris, amomum kravanh, immature bitter oranges, rhizoma cyperi, ligusticum wallichii, orange peels, polygonum cuspidatum, rhizoma corydalis, semen coicis, scutellaria baicalensis, sargentgloryvine stems, bletilla, millet and the like. The traditional Chinese medicine is remarkable in effect of treating chronic gastritis, has a remarkable effect of treating symptoms such as flautulence after meal, acid regurgitation, irregular stomachache, epigastric discomfort, ache, dyspepsia, vomiting, hiccup and nausea, and is simple in preparation method, stable in effect and less in side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of gastritis, be specifically related to a kind of Chinese medicine for the treatment of chronic gastritis and preparation method thereof.
?
Background technology
Chronic gastritis, refers to and the chronic inflammatory disease of the gastric mucosa being caused by the different causes of disease after its essence is that gastric epithelial suffers repeatedly to damage, causes mucosa to be reconstructed, and finally causes the atrophy of irreversible intrinsic gastric gland body, even disappears.Chronic gastritis often reduces with atrophy (mucosa loss of function) to a certain degree and gastrin secretion, the symptoms such as clinical symptoms main manifestations is Upper abdominal pain or discomfort, glutted, belch, feel sick, dyspepsia.Modern medicine is illustrated not yet completely to the cause of disease of chronic gastritis, and thinking may be with improper diet, malnutrition, organize the factor such as congestion and anoxia relevant.At present, patient conventionally takes Western medicine and treats, but Western medicine cure the symptoms, not the disease, can only respite symptom, can not eradicate old complaint, and in treatment gastritis, also tend to injure the organs such as Liver and kidney, curative effect is unstable, easily recurrence.
Summary of the invention
Object of the present invention is for above-mentioned deficiency, on the basis of secret prescription handed down in the family from generation to generation, in conjunction with modern Chinese and western medicine technology, a kind of Chinese medicine for the treatment of gastritis is provided, is to provide specifically this Chinese medicine and preparation method thereof, treating gastritis successful of the present invention, and nontoxic, have no side effect, effect stability, reparation technology is simple and easy to do.
Technical scheme of the present invention is as described below:
Preparation of the present invention is the composite preparation being prepared into by Herba Pogostemonis, Folium Perillae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Arecae, Radix Puerariae, Rhizoma Atractylodis, Fructus Atriplicis Sibiricae, Fructus Amomi Rotundus, Fructus Aurantii Immaturus, Rhizoma Cyperi, Rhizoma Chuanxiong, Pericarpium Citri tangerinae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Semen Coicis, Radix Scutellariae, Caulis Sargentodoxae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:
Herba Pogostemonis 12-20g Folium Perillae 10-22g Rhizoma Atractylodis Macrocephalae 8-18g
Pericarpium Arecae 10-18g Radix Puerariae 8-15g Rhizoma Atractylodis 10-20g
Fructus Atriplicis Sibiricae 8-16g Fructus Amomi Rotundus 12-20g Fructus Aurantii Immaturus 8-16g
Rhizoma Cyperi 10-18g Rhizoma Chuanxiong 10-18g Pericarpium Citri tangerinae 10-18g
Rhizoma Polygoni Cuspidati 8-15g Rhizoma Corydalis 6-15g Semen Coicis 8-15g
Radix Scutellariae 10-18g Caulis Sargentodoxae 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g
Semen setariae 10-20g.
In order to obtain better effect, the present invention preferably raw material mass mixture ratio is:
Herba Pogostemonis 12-18g Folium Perillae 10-18g Rhizoma Atractylodis Macrocephalae 8-12g
Pericarpium Arecae 12-18g Radix Puerariae 8-12g Rhizoma Atractylodis 10-15g
Fructus Atriplicis Sibiricae 8-12g Fructus Amomi Rotundus 12-16g Fructus Aurantii Immaturus 8-12g
Rhizoma Cyperi 10-15g Rhizoma Chuanxiong 10-14g Pericarpium Citri tangerinae 10-15g
Rhizoma Polygoni Cuspidati 8-12g Rhizoma Corydalis 6-10g Semen Coicis 8-12g
Radix Scutellariae 10-15g Caulis Sargentodoxae 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g
Semen setariae 12-18g.
Certainly, in order to obtain further good effect, the present invention also preferably raw material mass mixture ratio be:
Herba Pogostemonis 15g Folium Perillae 12g Rhizoma Atractylodis Macrocephalae 9g
Pericarpium Arecae 15g Radix Puerariae 10g Rhizoma Atractylodis 12g
Fructus Atriplicis Sibiricae 12g Fructus Amomi Rotundus 10g Fructus Aurantii Immaturus 8g
Rhizoma Cyperi 12g Rhizoma Chuanxiong 14g Pericarpium Citri tangerinae 12g
Rhizoma Polygoni Cuspidati 8g Rhizoma Corydalis 8g Semen Coicis 12g
Radix Scutellariae 10g Caulis Sargentodoxae 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 15g.
The preparation method of above-mentioned treatment chronic gastritis Chinese medicine, comprises the steps:
1), Folium Perillae put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care to surperficial micro-Jiao, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;
2), Herba Pogostemonis, the Rhizoma Atractylodis Macrocephalae, Pericarpium Arecae, Radix Puerariae, Fructus Atriplicis Sibiricae, Fructus Amomi Rotundus, Fructus Aurantii Immaturus, Semen setariae, Radix Scutellariae, Caulis Sargentodoxae are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;
3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time 10 times of pure water to decoct 1 hour, extract filtrate for subsequent use; Add for the second time 6 times of pure water to decoct half an hour, then collecting decoction filtration, for subsequent use;
4), remaining Rhizoma Atractylodis, Rhizoma Cyperi, Rhizoma Chuanxiong, Pericarpium Citri tangerinae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;
5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;
6), by above-mentioned steps 5) in the dry cream that obtains carry out micronizing powdered and cross 200 wood sieves, then powder is added to 3) collecting decoction in step, mix and shake up and can make.
The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can each also long-term drink, better effects if of drinking in right amount once of morning, noon and afternoon.
Theoretical foundation of the present invention is:
Herba Pogostemonis, acrid in the mouth, tepor.Return spleen, stomach, lung meridian.Eliminating turbid pathogen with aromatics, appetizing preventing or arresting vomiting, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, heat-damp in summer asthenia, uncomfortable in chest not easypro, cold-damp is closed summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.For the disease of retention of dampness in middle-JIAO, oppression sensation over the epigastrium and anorexia, normal and Rhizoma Polygoni Cuspidati is equal to use clinically.Go out for hygropyrexia, can join Rhizoma Atractylodis, Pericarpium Arecae, Radix Scutellariae and be equal to use.Be used for experiencing disease foul, that vomiting is had loose bowels, can join Folium Perillae, Fructus Amomi Rotundus, Fructus Atriplicis Sibiricae and be equal to use.For the disease of gastrofrigid vomiting, can join the Rhizoma Pinelliae with using; As damp and hot person, can join Rhizoma Coptidis, Caulis Bambusae In Taenia; Weakness of the spleen and stomach person, can join Radix Codonopsis, Radix Glycyrrhizae; Vomiting during pregnancy, can join Fructus Amomi with using.It controls the disease of heat-damp in summer, though partially cold, partial heat all can apply, clinical often with Herba Eupatorii compatibility with use.The disease that has retention of dampness in middle-JIAO for affection of exogenous wind-cold concurrently, Chang Peiwu Folium Perillae, Pericarpium Citri Reticulatae are equal to use.In addition, can control nasal sinusitis, often join Fel Sus domestica and be equal to use.
Folium Perillae, nature and flavor: pungent, tepor, nontoxic, cure mainly stagnation of QI in spleen and stomach, uncomfortable in chest, the card of vomiting.This product tool promoting the circulation of QI to alleviate the stagnation in middle-JIAO, stomach function regulating preventing or arresting vomiting effect.Partially cold person, every and Herba Pogostemonis is same to be used; Partial heat person, can be with Rhizoma Coptidis with using.Stagnation of QI expectorant knot person partially, normal and the Rhizoma Pinelliae, Cortex Magnoliae Officinalis are used together.All retention of dampness due to stagnation of QI, disorder of stomach-QI, gastral cavity abdominal distention is vexed, vomiting and nausea diarrhoea person, can with the compatibilities such as Herba Pogostemonis, Pericarpium Citri Reticulatae, Pinellia leaven, Poria, with circulation of qi promoting removing dampness for regulating stomach.Cure mainly affection of exogenous wind-cold, fever with aversion to cold, has a headache lossless, cough and asthma, and gastral cavity abdominal distention is vexed, and vomiting and nausea diarrhoea, blocks in pharynx, pregnancy reactions, frequent fetal movement, ichthyophagy Eriocheir sinensis is poisoning, and carbuncle skin ulcer snake venom is peppery.
The Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis Macrocephalae bitter in the mouth, sweet, warm in nature; Return spleen, stomach warp; Fragrance matter is soft, can rise and can fall, and keep and do not walk to have invigorating the spleen and benefiting QI, dampness diuretic, strengthening superficial resistance to stop perspiration, antiabortive effect, cures mainly deficiency-weakness of spleen-QI, lack of appetite abdominal distention, diarrhea; Phlegm retention, edema, dysuria, arthralgia chiefly caused by damp pathogen is ached, spontaneous sweating due to deficiency of QI, frequent fetal movement.Numbness is controlled in inducing diuresis to remove edema, strengthening superficial resistance to stop perspiration, dehumidifying should give birth to use; Invigorating the spleen and regulating the stomach should be fried use; Invigorating the spleen to arrest diarrhea should be used by parching to brown.Deficiency of spleen-QI, the thin yellowish complexion of shape, anorexia, distension and fullness in the abdomen, the large thin person in loose stool, can with the compatibility such as Radix Ginseng, Poria, Radix Glycyrrhizae Preparata, to increase the merit of invigorating the spleen and benefiting QI.Past have report the Rhizoma Atractylodis Macrocephalae to gastrointestinal function (as the gastric secretion of gastric acid, propelling property enterokinesia etc.) without impact, also without antiulcer, antiinflammatory and analgesic activity, do not affect normal body temperature, to central nervous system, without obvious inhibitory action, the latter is considered to can be used as the foundation distinguishing with Rhizoma Atractylodis.Nearly report, how not identical the Rhizoma Atractylodis Macrocephalae is on the impact of isolated small intestines of rabbits spontaneous activity, and the Rhizoma Atractylodis Macrocephalae can strengthen the activity of Isolated rabbit intestine Spontaneous Contraction, and its shrinkage amplitude is strengthened, Rhizoma Atractylodis Macrocephalae oil suppresses the autonomic movement of intestinal tube, or the Rhizoma Atractylodis Macrocephalae is not obvious on the autonomic movement impact of isolated small intestines of rabbits.Rhizoma Atractylodis Macrocephalae extract 50mg and 200mg/kg gastric infusion, to animal water-immersion restraint stress ulcer, have remarkable inhibition.
Pericarpium Arecae, acrid in the mouth; Slightly warm in nature.Return spleen, stomach, large intestine, small intestine meridian.Cure mainly the gastrointestinal stagnation of QI, gastral cavity abdominal distention is vexed, defecates not well.The pungent energy of these product be manageed it loose, and master enters taste warp, and energy circulation of qi promoting intestinal stasis relieving, is the prompt medicine of alleviating distention in middle-JIAO promoting the circulation of QI.The gastral cavity abdomen painful abdominal mass of controlling stagnation of QI due to dyspepsia is swollen, and belch acid regurgitation, constipation or rush down and not well can be equal to use with Fructus Aurantii Immaturus; If control the distension and fullness in the abdomen of retention of damp leading to blockage of QI, can be equal to use with Herba Pogostemonis, Rhizoma Chuanxiong, Cortex Magnoliae Officinalis.Ancient books " Japan hanako materia medica ": lower all gas, only cholera, logical intestine and small intestine, spleen benefiting and stimulating the appetite, in tune." Kaibao Bencao ": the main cold and hot gas abdomen of making a psychological attack, large intestine is stopped up poison, expectorant diaphragm, the belching of acid from stomach.And decoct with Jiang Yantong, enter to dredge gas medicine good." detailed outline ": lowering the adverse flow of QI, aqueous vapor edema in the skin that disappears, beriberi is stopped up contrary, subtertian malaria feeling of fullness, nausea malignant histocytosis feeling of distension and oppression." book on Chinese herbal medicine is new again ": eliminating the pathogens from the lung, easing stomach-QI, dampness removing chases after wind, wide intestinal detumescence, reason waist beriberi, treating malaria disease dysentery.
Radix Puerariae, nature and flavor are sweet, pungent, cool, are diaphoretic medicine, cure mainly fever caused by exogenous pathogens, rigidity pain on the head and nape, measles from the beginning of, rash go out smooth, epidemic febrile disease is thirsty, quench one's thirst, have loose bowels, dysentery, hypertension, coronary heart disease.
Rhizoma Atractylodis, general root stock is used as medicine, and is activating the spleen medicine, and the bitter Wen Xinlie of nature and flavor, has dampness, changes effect turbid, pain relieving.Rhizoma Atractylodis have drying damp and strengthening spleen, effect of wind-damp dispelling.Cure mainly retention of dampness in middle-JIAO, anemofrigid-damp arthralgia, foot swelling and pain in knee, flaccidity is soft unable, nyctalopia nyctalopia." pearl sac " day: " can stomach invigorating pacify spleen, non-this of all damp-edema can not remove." Compendium of Material Medica says: " control damp-phlegm prolonged fluid-retention ... and spleen is wet dirty, turbid drop leukorrhagia, the sliding hemorrhoidal hamorrhage that rushes down." " Newly Revised Canon of Materia Medica " claim it can " diuresis " to adjust gastrointestinal motility function; Rhizoma Atractylodis decoct, atractylol extract can obviously be alleviated isolated small intestines of rabbits spasm due to acetylcholine in range of doses; and intestinal motility due to epinephrine is suppressed, there is certain antagonism.
Antiulcer: Rhizoma Atractylodis have stronger antiulcer action.Experiment is found, Atractylodes lancea (Thunb.) DC. and Atractylis chinensis have stronger inhibitory action to pyloric ligation ulcers ulcer, pylorus ligation-aspirin ulcer, stress ulcer, and two kinds of Rhizoma Atractylodis all can significantly suppress gastric juice amount, total acidity, total digestion power and the Gastric mucosal lesion of ulcer, animal.
Fructus Atriplicis Sibiricae, can suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.
Fructus Amomi Rotundus is perennial evergreen herbaceous plant, produces the south of the Five Ridges.Permitted for high zhang, outer image Musa basjoo Sieb. Et Zucc., Ye great, lanceolar, spends faint yellowly, and autumn is solid, fruit oblate spheroid, seed, as Semen Granati, can be used as medicine, savory.Can be used for the removing dampness painful abdominal mass that disappears, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.For turbid damp obstructing in middle-JIAO, anorexia, hygropyrexia from the beginning of, uncomfortable in chest not hungry, cold-damp vomiting, chest and abdomen swelling and pain, food stagnation does not disappear.
Fructus Aurantii Immaturus, bitter in the mouth; Pungent; Cold.Return spleen, stomach, liver, heart channel.In effect is stagnant, stop; Feeling of fullness distending pain; Constipation; Heavy after dysentery; Blocked-up chest; Gastroptosis; Uterine prolapse; Proctoptosis.The effect of Fructus Aurantii Immaturus to gastrointestinal: the intestine in vitro of water decoction, tincture and the fluid extract of Fructus Aurantii Immaturus, Fructus Aurantii to mice, rabbit and rabbit all have inhibitory action at body intestinal tube, it is strong that decocting liquid makes the gastrointestinal of stomach, intestinal fistula Canis familiaris L. shrink the rhythm and pace of moving things, being excitation, but suppressing Canis familiaris L. at body gastrointestinal motility. Furctus Aurantii Immaturus extract shrinks and has obvious antagonism intestinal tube due to acetylcholine and histamine.
The Rhizoma Cyperi resolving depression of can regulating the flow of vital energy, menstruction regulating and pain relieving; Antiabortive.Main distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
The effect of Rhizoma Cyperi to gastrointestinal: preparation man's rabbits infestines according to a conventional method, trace the impact of Rhizoma Cyperi volatile oil on intestine in vitro with kymograph.Result shows, can suppress the contraction of intestinal tube in the time that Rhizoma Cyperi volatile oil concentration is 5 μ g/ml, and in the time that concentration is increased to 20 μ g/ml, aobvious obvious inhibitory action, declines the reduction of intestinal tube shrinkage amplitude, tension force.Singh N also reports, when cyperol extract 20 μ g/ml concentration, isolated rabbit ileum smooth muscle is had to direct repression, controls gas disease trusted subordinate distension, chest and diaphragm dysphagia, eructation acid regurgitation, in stomach the contrary vomiting of expectorant and be drunk overnight puzzled, anorexia.
Rhizoma Chuanxiong acrid in the mouth, warm in nature, return liver, gallbladder, heart channel, the fragrant liter of gas fallen apart, have blood-activating and qi-promoting, effect of wind-expelling pain-stopping, cures mainly menoxenia, dysmenorrhea, amenorrhea, difficult labour, retention of placenta, lochia stomachache, lump, heart pain in chest and hypochondrium, traumatic injury swells and ache, headache vertigo and head dark, anemofrigid-damp arthralgia, numb limbs and tense tendons, ulcer sores.
Pericarpium Citri tangerinae, acrid in the mouth and micro-hardship, temperature, enters spleen, lung meridian.In reasonable controlled atmosphere, drying dampness to eliminate phlegm effect, can be used for treating stagnation of QI in spleen and stomach, distension and fullness in the abdomen, vomiting, or uncomfortable in chest due to turbid damp obstructing in middle-JIAO, indigestion and loss of appetite, loose stool, but YIN fluid deficiency, person is cautious use of inside to have excess-heat, for insufficiency of the spleen diet reduce, dyspepsia, and the disease such as nausea and vomiting.This product dampness and can spleen benefiting and stimulating the appetite, is applicable to the diseases such as weakness of the spleen and stomach, diet minimizing, dyspepsia, loose stool and diarrhea, the fit applications such as the normal and Rhizoma Atractylodis Macrocephalae, Poria.Can spleen invigorating because of it, can regulate the flow of vital energy again, therefore often make as the assistant of Qi-tonifying drug, can make tonify without causing stagnation, prevent from stopping up the swollen effect of doing of holding back.
Rhizoma Polygoni Cuspidati, micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian, root stock hyoscine, invigorate blood circulation, dissipating blood stasis, stimulate the menstrual flow, the effect such as antitussive, can heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, postnatal blood stasis is not Xiaed ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, traumatic injury, carbuncle sore tumefacting virus.
Rhizoma Corydalis, is bloodroot, is used as medicine with tuber, has promoting blood circulation to remove blood stasis, and the effect of regulating QI to relieve pain cures mainly stomachache, dysmenorrhea, traumatic injury etc., and its acrid in the mouth, hardship are warm in nature.There is promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving, for pain of the each portion of whole body qi depression to blood stasis, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Semen Coicis, cool in nature, sweet in the mouth, light, is the kernel of grass Semen Coicis.There is spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For effect of edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.Function cures mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Radix Scutellariae, Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.For labiate, be used as medicine with root.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.
Caulis Sargentodoxae, bitter in the mouth is flat.Return large intestine, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, invigorate blood circulation, and dispel the wind.For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling.There is the eliminating carbuncle of relieving internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide.Control acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, the diseases such as injury from falling down.
The Pseudobulbus Bletillae (Rhizoma Bletillae), cold in nature, bitter in the mouth, sweet, puckery, nontoxic; Return lung, stomach, Liver Channel.There is astringing to arrest bleeding, the function of detumescence and promoting granulation.Cure mainly slightly blood of pulmonary tuberculosis, spit blood, epistaxis, has blood in stool, traumatic hemorrhage, carbuncle pyogenic infections from tumour or sore, scrofula, anal fistula, burn and scald, rhagadia manus et pedis, the diseases such as anal fissure.With other drug matchings of the present invention, treatment gastritis successful.
Semen setariae, is foxtail millet (Setaria italica) grain of making that shells, because it is little, and diameter 1 millimeter, therefore named.Originate in the north of China Huanghe valley, the staple food crop of ancient Chinese, so Xia dynasty and Shang dynasty belong to " foxtail millet culture ".Foxtail millet growth is drought-enduring, various in style, is commonly called as " foxtail millet has the five colours ", Semen setariae sweet in the mouth cool in nature, can disappear by preventing or arresting vomiting, nourishing the stomach, relieving constipation, stopping leak, blood yiqi, spleen invigorating, hypoglycemic and thirst-relieving, yin nourishing tonify deficiency, has good conditioning and tonic effect to gastrointestinal tract: cure mainly dyspepsia: vitamin B group can be secreted by facilitating digestion liquid, maintain and promote and be conducive to defecation by intestinal peristalsis promoting.And effect of the raw skin ulcer of bicker, and nourishing the stomach: in and gastric acid, alleviate stomachache.Semen setariae has the effect that prevents general stomach, vomiting.
From China's Traditional Chinese Medicine angle, the etiology and pathogenesis of chronic gastritis, there is eating and drinking without temperance, kill damaging the spleen and stomach state, or invade in exopathogen, undermine taste, or suffering is disgruntled, the liver failing to maintain the normal flow of QI, perverse and unreasonable manner is violated stomach, and innate deficiency, the situations such as weakness of the spleen and stomach, its sick table is at " stomach ", but with " spleen ", " liver ", " kidney " is in close relations, pathogenic characteristic is deficiency complicated with excess, therefore the compositions obtaining by the above-mentioned drug matching of the present invention and preparation method, adopt dialectical method effectively to reach effect of regulating stomach and the vital organs of the human body, have no side effect, effect stability, reach the curative effect of getting twice the result with half the effort compared with Western medicine.
clinical experiment 1:
1), observing time: in the situation that technical solution of the present invention does not disclose, select 6 months of year August in March, 2013 to 2013.
2), the object of observation: select 10 routine chronic gastritis cases in Shenzhen City, Guangdong Province Gastroenterology dept. of institute of traditional Chinese medicine: male 6 examples, female's 4 examples; Age: 40-55 years old 5 example, 60-75 years old 5 example; Occupation: common working clan's 5 examples, retired person 5 examples.Disease: glutted after meal, pantothenic acid, the symptoms such as irregularities stomachache.
3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.
4), observing effect:
Taking continuously after 3 courses for the treatment of, glutted after meal, pantothenic acid, 6 examples that the symptoms such as irregularities stomachache substantially no longer occur, have feeling of repletion after meal a little, slight pantothenic acid, 2 examples that the symptoms such as the slight stomachache of irregularities substantially no longer occur, glutted after meal, pantothenic acid, irregularities stomachache is improved unconspicuous 2 examples, total effective rate 80%.
clinical experiment 2 :
1), observing time: in the situation that technical solution of the present invention does not disclose, select in April, 2013 to 2013 year JIUYUE 6 months.
2), the object of observation: 20 routine cases are selected by Gastroenterology dept. of institute of traditional Chinese medicine in Futian District, Shenzhen City, Guangdong Province: male 12 examples, female's 8 examples; Age: 32-55 years old 10 example, 56-75 years old 10 example; Occupation: post civil servant 10 examples that once assumed the leadership, common teachers 10 examples.Disease: epigastric discomfort, pain, dyspepsia, vomiting, singultus is nauseating etc.
3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.
4), observing effect:
Taking continuously after 3 courses for the treatment of, the abdominal pain that patient is original, dyspepsia disappears, vomiting, singultus and nauseating 12 examples that substantially no longer occur that wait, slight abdominal pain and dyspepsia, once in a while slightly vomiting, singultus and 3 examples of feeling sick, abdominal pain, dyspepsia disappears, vomiting, singultus and unconspicuous 5 examples of improvement of feeling sick, total effective rate 75%.
clinical experiment 3 :
1), observing time: in the situation that technical solution of the present invention does not disclose, select in July, 2013 to 2013 year December 6 months.
2), the object of observation: select 30 routine cases in Gastroenterology dept. of Song Gang the People's Hospital, Shenzhen City, Guangdong Province: male 12 examples, female's 18 examples; Age: 35-55 years old 16 example, 60-75 years old 14 example; Occupation: the common master of private enterprise 14 examples, common retired professor's 16 examples.Disease: glutted after meal, pantothenic acid, irregularities stomachache, epigastric discomfort, pain, dyspepsia, vomiting, singultus is nauseating etc.
3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.
4), observing effect:
Taking continuously after 3 courses for the treatment of, the abdominal pain that patient is original, dyspepsia disappears, vomiting, singultus and nauseating 18 examples that substantially no longer occur that wait, slight abdominal pain and dyspepsia, once in a while slightly vomiting, singultus and 6 examples of feeling sick, abdominal pain, dyspepsia, vomiting, singultus and unconspicuous 6 examples of improvement of feeling sick, total effective rate 80%.
In conjunction with above clinical data and theoretical foundation of the present invention, visible beneficial effect of the present invention is, the preparation that the present invention makes has good result for treatment chronic gastritis, and nontoxic, have no side effect, and effect stability, reparation technology is simple and easy to do.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is explained detailedly:
embodiment 1:
Preparation of the present invention is the composite preparation being prepared into by Herba Pogostemonis, Folium Perillae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Arecae, Radix Puerariae, Rhizoma Atractylodis, Fructus Atriplicis Sibiricae, Fructus Amomi Rotundus, Fructus Aurantii Immaturus, Rhizoma Cyperi, Rhizoma Chuanxiong, Pericarpium Citri tangerinae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Semen Coicis, Radix Scutellariae, Caulis Sargentodoxae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:
Herba Pogostemonis 12g Folium Perillae 10g Rhizoma Atractylodis Macrocephalae 10g
Pericarpium Arecae 12g Radix Puerariae 12g Rhizoma Atractylodis 15g
Fructus Atriplicis Sibiricae 10g Fructus Amomi Rotundus 12g Fructus Aurantii Immaturus 8g
Rhizoma Cyperi 15g Rhizoma Chuanxiong 15g Pericarpium Citri tangerinae 13g
Rhizoma Polygoni Cuspidati 12g Rhizoma Corydalis 8g Semen Coicis 10g
Radix Scutellariae 12g Caulis Sargentodoxae 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 16g.
The preparation method of above-mentioned treatment chronic gastritis Chinese medicine, comprises the steps:
1), Folium Perillae put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care to surperficial micro-Jiao, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;
2), Herba Pogostemonis, the Rhizoma Atractylodis Macrocephalae, Pericarpium Arecae, Radix Puerariae, Fructus Atriplicis Sibiricae, Fructus Amomi Rotundus, Fructus Aurantii Immaturus, Semen setariae, Radix Scutellariae, Caulis Sargentodoxae are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;
3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time the little fire of 8 times of pure water to decoct 1 hour, add for the second time 4 times of little fire of pure water to decoct half an hour, then collecting decoction filtering, for subsequent use;
4), remaining Rhizoma Atractylodis, Rhizoma Cyperi, Rhizoma Chuanxiong, Pericarpium Citri tangerinae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;
5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;
6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added to the collecting decoction in step 3), mix shake up and can make.
The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can respectively drink once and long-term drink better effects if the morning, noon and afternoon.
embodiment 2:
The present invention also preferably raw materials quality be (gram):
Herba Pogostemonis 12g Folium Perillae 10g Rhizoma Atractylodis Macrocephalae 10g
Pericarpium Arecae 12g Radix Puerariae 12g Rhizoma Atractylodis 15g
Fructus Atriplicis Sibiricae 10g Fructus Amomi Rotundus 12g Fructus Aurantii Immaturus 8g
Rhizoma Cyperi 15g Rhizoma Chuanxiong 10g Pericarpium Citri tangerinae 13g
Rhizoma Polygoni Cuspidati 12g Rhizoma Corydalis 8g Semen Coicis 10g
Radix Scutellariae 12g Caulis Sargentodoxae 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 16g.
Preparation method is as embodiment 1.
embodiment 3:
The present invention also preferably raw materials quality be (gram):
Herba Pogostemonis 15g Folium Perillae 12g Rhizoma Atractylodis Macrocephalae 9g
Pericarpium Arecae 15g Radix Puerariae 10g Rhizoma Atractylodis 12g
Fructus Atriplicis Sibiricae 12g Fructus Amomi Rotundus 10g Fructus Aurantii Immaturus 8g
Rhizoma Cyperi 12g Rhizoma Chuanxiong 14g Pericarpium Citri tangerinae 12g
Rhizoma Polygoni Cuspidati 8g Rhizoma Corydalis 8g Semen Coicis 12g
Radix Scutellariae 10g Caulis Sargentodoxae 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 15g.
Preparation method is as embodiment 1.
embodiment 4:
The present invention also preferably raw materials quality be (gram):
Herba Pogostemonis 18g Folium Perillae 15g Rhizoma Atractylodis Macrocephalae 12g
Pericarpium Arecae 16g Radix Puerariae 12g Rhizoma Atractylodis 15g
Fructus Atriplicis Sibiricae 13g Fructus Amomi Rotundus 15g Fructus Aurantii Immaturus 12g
Rhizoma Cyperi 16g Rhizoma Chuanxiong 14g Pericarpium Citri tangerinae 16g
Rhizoma Polygoni Cuspidati 10g Rhizoma Corydalis 12g Semen Coicis 15g
Radix Scutellariae 16g Caulis Sargentodoxae 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 12g
Semen setariae 18g.
Preparation method is as embodiment 1.
embodiment 5 :
The present invention also preferably raw materials quality be (gram):
Herba Pogostemonis 16g Folium Perillae 18g Rhizoma Atractylodis Macrocephalae 15g
Pericarpium Arecae 14g Radix Puerariae 15g Rhizoma Atractylodis 18g
Fructus Atriplicis Sibiricae 15g Fructus Amomi Rotundus 18g Fructus Aurantii Immaturus 14g
Rhizoma Cyperi 18g Rhizoma Chuanxiong 16g Pericarpium Citri tangerinae 14g
Rhizoma Polygoni Cuspidati 12g Rhizoma Corydalis 13g Semen Coicis 13g
Radix Scutellariae 18g Caulis Sargentodoxae 15g Pseudobulbus Bletillae (Rhizoma Bletillae) 15g
Semen setariae 18g.
Preparation method is as embodiment 1.
embodiment 6 :
The present invention also preferably raw materials quality be (gram):
Herba Pogostemonis 15g Folium Perillae 18g Rhizoma Atractylodis Macrocephalae 15g
Pericarpium Arecae 16g Radix Puerariae 15g Rhizoma Atractylodis 20g
Fructus Atriplicis Sibiricae 12g Fructus Amomi Rotundus 20g Fructus Aurantii Immaturus 16g
Rhizoma Cyperi 16g Rhizoma Chuanxiong 18g Pericarpium Citri tangerinae 15g
Rhizoma Polygoni Cuspidati 15g Rhizoma Corydalis 15g Semen Coicis 12g
Radix Scutellariae 16g Caulis Sargentodoxae 16g Pseudobulbus Bletillae (Rhizoma Bletillae) 13g
Semen setariae 20g.
Preparation method is as embodiment 1.
Above-described embodiment is only the several of the numerous embodiments of the present invention, and as each formula strengthened in the ratio in technical scheme or reducing dose, this treatment chronic gastritis preparation curative effect making is also unaffected, within also will dropping on the scope of the present invention.
Claims (4)
1. treat the Chinese medicine of chronic gastritis for one kind, it is characterized in that, preparation of the present invention is the composite preparation being prepared into by Herba Pogostemonis, Folium Perillae, the Rhizoma Atractylodis Macrocephalae, Pericarpium Arecae, Radix Puerariae, Rhizoma Atractylodis, Fructus Atriplicis Sibiricae, Fructus Amomi Rotundus, Fructus Aurantii Immaturus, Rhizoma Cyperi, Rhizoma Chuanxiong, Pericarpium Citri tangerinae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Semen Coicis, Radix Scutellariae, Caulis Sargentodoxae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:
Herba Pogostemonis 12-20g Folium Perillae 10-22g Rhizoma Atractylodis Macrocephalae 8-18g
Pericarpium Arecae 10-18g Radix Puerariae 8-15g Rhizoma Atractylodis 10-20g
Fructus Atriplicis Sibiricae 8-16g Fructus Amomi Rotundus 12-20g Fructus Aurantii Immaturus 8-16g
Rhizoma Cyperi 10-18g Rhizoma Chuanxiong 10-18g Pericarpium Citri tangerinae 10-18g
Rhizoma Polygoni Cuspidati 8-15g Rhizoma Corydalis 6-15g Semen Coicis 8-15g
Radix Scutellariae 10-18g Caulis Sargentodoxae 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g
Semen setariae 10-20g.
2. the Chinese medicine for the treatment of chronic gastritis according to claim 1, is further characterized in that, wherein the quality proportioning of each component is:
Herba Pogostemonis 12-18g Folium Perillae 10-18g Rhizoma Atractylodis Macrocephalae 8-12g
Pericarpium Arecae 12-18g Radix Puerariae 8-12g Rhizoma Atractylodis 10-15g
Fructus Atriplicis Sibiricae 8-12g Fructus Amomi Rotundus 12-16g Fructus Aurantii Immaturus 8-12g
Rhizoma Cyperi 10-15g Rhizoma Chuanxiong 10-14g Pericarpium Citri tangerinae 10-15g
Rhizoma Polygoni Cuspidati 8-12g Rhizoma Corydalis 6-10g Semen Coicis 8-12g
Radix Scutellariae 10-15g Caulis Sargentodoxae 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g
Semen setariae 12-18g.
3. the Chinese medicine for the treatment of chronic gastritis according to claim 1 and 2, is further characterized in that, wherein the quality proportioning of each component is:
Herba Pogostemonis 15g Folium Perillae 12g Rhizoma Atractylodis Macrocephalae 9g
Pericarpium Arecae 15g Radix Puerariae 10g Rhizoma Atractylodis 12g
Fructus Atriplicis Sibiricae 12g Fructus Amomi Rotundus 10g Fructus Aurantii Immaturus 8g
Rhizoma Cyperi 12g Rhizoma Chuanxiong 14g Pericarpium Citri tangerinae 12g
Rhizoma Polygoni Cuspidati 8g Rhizoma Corydalis 8g Semen Coicis 12g
Radix Scutellariae 10g Caulis Sargentodoxae 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 15g.
4. a preparation method for the treatment of the Chinese medicine of chronic gastritis, is characterized in that, it comprises the steps:
1), Folium Perillae put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care to surperficial micro-Jiao, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;
2), Herba Pogostemonis, the Rhizoma Atractylodis Macrocephalae, Pericarpium Arecae, Radix Puerariae, Fructus Atriplicis Sibiricae, Fructus Amomi Rotundus, Fructus Aurantii Immaturus, Semen setariae, Radix Scutellariae, Caulis Sargentodoxae are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;
3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time the little fire of 10 times of pure water to decoct 1 hour, extract filtrate for subsequent use, add for the second time 6 times of little fire of pure water to decoct half an hour, then collecting decoction filtration, for subsequent use;
4), remaining Rhizoma Atractylodis, Rhizoma Cyperi, Rhizoma Chuanxiong, Pericarpium Citri tangerinae, Rhizoma Polygoni Cuspidati, Rhizoma Corydalis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;
5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;
6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added to the collecting decoction in step 3), mix and shake up and can make, the above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can each also long-term drink, better effects if of drinking in right amount once of morning, noon and afternoon.
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| CN201410123821.4A CN103877483A (en) | 2014-03-31 | 2014-03-31 | Traditional Chinese medicine for treating chronic gastritis and preparation method thereof |
| PCT/CN2014/075340 WO2015149393A1 (en) | 2014-03-31 | 2014-04-15 | Traditional chinese medicine for treating chronic gastritis and preparation method therefor |
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| CN103861015A (en) * | 2014-03-31 | 2014-06-18 | 袁志贤 | Traditional Chinese medicine for treating chronic enteritis and preparation method thereof |
| CN104083747A (en) * | 2014-07-28 | 2014-10-08 | 成都中医药大学 | Medicinal composition for treating chronic gastritis as well as preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108355060A (en) * | 2018-04-17 | 2018-08-03 | 王华凌 | A kind of Chinese medicine for treating a variety of diseases of stomach |
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Cited By (4)
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| CN104083747B (en) * | 2014-07-28 | 2018-02-16 | 成都中医药大学 | A kind of pharmaceutical composition for treating chronic gastritis and preparation method and purposes |
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| WO2015149393A1 (en) | 2015-10-08 |
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