WO2015149393A1

WO2015149393A1 - Traditional chinese medicine for treating chronic gastritis and preparation method therefor

Info

Publication number: WO2015149393A1
Application number: PCT/CN2014/075340
Authority: WO
Inventors: 袁志贤
Original assignee: 袁志贤
Priority date: 2014-03-31
Filing date: 2014-04-15
Publication date: 2015-10-08
Also published as: CN103877483A

Abstract

Traditional Chinese medicine for treating chronic gastritis and preparation method therefor, comprising Pogostemon cablin, Perilla frutescens, Atractylodes macrocephala, Areca catechu, Pueraria edulis Pamp., Atractylodes lancea, Tribulus terrestris, Alpinia katsumadai Hayata, Aurantii Immaturus Fructus, Cyperus rotundus, Ligusticum striatum, Pericarpium Citri Reticulatae, Fallopia japonica, Corydalis yanhusuo, Coix lacryma-jobi, Scutellaria baicalensis, Sargentodoxa cuneata, Bletilla striata, and Setaria italica, said ingredients being subjected to processes of powdering, decoction, ethanol extraction and mixing into a liquid preparation.

Description

Traditional Chinese medicine for treating chronic gastritis and preparation method thereof

The invention relates to a traditional Chinese medicine for treating gastritis, in particular to a traditional Chinese medicine for treating chronic gastritis and a preparation method thereof. Background technique

Chronic gastritis refers to chronic inflammation of the gastric mucosa caused by different causes. The essence is that the gastric mucosal epithelium suffers repeated damage, leading to mucosal remodeling, which eventually leads to irreversible atrophy or disappearance of the intrinsic gastric gland. Chronic gastritis is often accompanied by a certain degree of atrophy (visual membrane loss) and decreased secretion of gastrin. The clinical symptoms are mainly symptoms of upper abdominal pain or discomfort, fullness, belching, nausea, and indigestion. The etiology of chronic gastritis in modern medicine has not been fully elucidated and may be related to factors such as improper diet, malnutrition, tissue congestion and hypoxia. At present, patients usually take Western medicine to treat, but Western medicine can not cure the symptoms, can only temporarily relieve the symptoms, and can not eradicate the roots, and in the treatment of gastritis, it will often hurt the liver and kidney and other organs, the effect is unstable, easy to relapse. Summary of the invention

The object of the present invention is to provide a traditional Chinese medicine for treating gastritis based on the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and specifically to provide such a traditional Chinese medicine and a preparation method thereof, and the therapeutic effect of the gastritis of the invention is obvious. It is non-toxic, has no side effects, and has a stable effect. The preparation process is simple and easy. The technical solution of the present invention is as follows:

The preparation of the invention is made up of patchouli, perilla leaf, atractylodes, big belly skin, gange, atractylodes, white peony, cardamom, medlar, fragrant, chuanxiong, orange peel, polygonum cuspidatum, yuanhu, coix seed, jaundice, A preparation of a composition prepared by big blood vine, white peony and millet, wherein the quality of each component is matched with patchouli 12-20g perilla leaves 10-22g atractylodes

8-18g

Big belly skin 10-18g Gange 8-15g Atractylodes

10-20g

White peony 8-16g soybean meal 12-20g

8-16g

香附10-18g Chuanxiong 10-18g

10-18g

Yuan Hu 6-15g 薏苡二

8-15g

黄芩 10-18g 大血藤 8-16g white

8-15g

Millet 10-20g.

In order to obtain a better effect, the preferred raw material quality ratio of the present invention is

Patchouli 12-18g Perilla Leaf 10-18g Atractylodes

8-12g

Big belly skin 12-18g Gange 8-12g Atractylodes 10-15g

White peony 8-12g Bean curd 12-16g 枳 8 8-12g 香附 10-15g 芎 10-14g Orange peel 10-15g Polygonum cuspidatum 8-12g Yuanhu 6-10g Huanren -12g

Astragalus 10-15g: blood vine 8-12g white peony 8-12g millet 12-18g.

Of course, in order to obtain further good effects, the present invention can also be preferably used as raw material. Musk 15g Perilla leaf 12g Atractylodes 9g Large belly skin 15g Gange 10g Atractylodes Rhizome 12g White peony 12g Bean meal 10g 枳 8 8g 香香12g Chuanxiong 14g Orange Skin 12g Polygonum cuspidatum 8g Yuanhu 8g Coix seed 12g Astragalus 10g Big blood vine 8g White peony 10g

Millet 15g.

The above preparation method for treating traditional Chinese medicine for chronic gastritis includes the following steps:

1), put the perilla leaves in a small pot and stir fry until the surface is slightly coke, and then pass through the crusher powder and pass through the 80 mesh sieve, and set aside;

2), the patchouli, atractylodes, abdomen, gane, white peony, cardamom, medlar, millet, scutellaria, big blood vine are proportioned well, pulverized into powder through a pulverizer and passed through a 90 mesh sieve, natural Dry, spare; 3), mix the powders of each component in step 1) and 2), add boiling water twice, add 10 times pure water for 1 hour, extract the filtrate for use; 6 times pure water decoction for half an hour, then combine the decoction and filter, spare;

4), the remaining Atractylodes, Astragalus, Chuanxiong, Orange Peel, Polygonum cuspidatum, Yuanhu, Coix seed, and white peony are proportioned well, pulverized into powder after crushing machine and passed through 80 mesh sieve, naturally dried, ready for use;

5), mixing the powders of each component in step 4), adding 4 to 6 times 70%~80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;

6), the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200-sieving sieve, and then the powder is added to 3) the combined decoction in the step, and the mixture is shaken to obtain.

The prepared Chinese medicine composition solution preparation can be used for oral administration, and if it can be consumed once in the morning and evening, and it is used for a long time, the effect is better. The theoretical basis of the present invention is: patchouli, Weixin, lukewarm. Return to the spleen, stomach, lungs. Aromatized turbid, appetizing and vomiting, published heat. For wet turbidity, vomiting, sputum, heat and dampness, chest tightness, uncomfortable, cold and dampness, abdominal pain, vomiting and diarrhea, nasal headache. It is used in the symptoms of wet resistance, coke, and suffocation. It is often used in clinical practice with Polygonum cuspidatum. For the use of wet temperature, it can be used with Atractylodes, Big Belly, and Astragalus. It is used to feel turbidity, vomiting and diarrhea. It can be used with basil leaves, cardamom and white peony. For the symptoms of stomach cold and vomiting, it can be used with Pinellia; for dampness, it can be matched with Huanglian and Zhuru; those with weak spleen and stomach can be combined with Codonopsis pilosula and licorice; pregnancy vomiting, can be used with Amomum villosum. Its cure for dampness, whether it is cold or partial, can be applied. It is often used in combination with Perrin. It is used for the symptoms of exogenous cold and dampness in the coke. It is often used in combination with perilla and tangerine peel. In addition, can cure the nose, often with pig bile equivalent. Perilla leaf, sexual taste: Xin, lukewarm, non-toxic, attending spleen and stomach qi stagnation, chest tightness, vomiting. This product has a wide range of qi, and stomach vomiting effect. Those who are cold, each with the use of patchouli; those who are hot, can be used with yellow. People with partial qi stagnation, often used with Pinellia and Magnolia. Anyone with qi stagnation, stomach qi, suffocation, vomiting, and vomiting, can be combined with patchouli, dried tangerine peel, Pinellia sinensis, medlar, etc. Indications of cold, aversion to cold, fever, headache, no sweat, cough and asthma, abdominal distension, vomiting diarrhea, pharyngeal obstruction, pregnancy resistance, fetal dysphoria, fish and crab poisoning, hemorrhoids snake poison. Atractylodes, Atractylodes bitter, sweet, warm; spleen, stomach; aroma soft, can be raised or lowered, keep not spleen and qi, dry and damp, water, antiperspirant, anti-fetal effect, Indications of temper weakness, eating less abdominal distension, stool diarrhea; sipping, edema, dysuria, wet and sore, qi deficiency and spontaneous sweating, fetal movement. Lishui swelling, solid table antiperspirant, dehumidification treatment should be used for health; spleen and stomach should be fried; spleen and diarrhea should be used for scorching. Insufficient temper, thin face, yellow, do not think about diet, abdominal fullness, thin stools, can be combined with ginseng, medlar, licorice, etc., to strengthen the spleen and Qi. In the past, it has been reported that Atractylodes has no effect on gastrointestinal function (such as gastric acid secretion of gastric acid, propulsive intestinal peristalsis, etc.), and has no anti-ulcer, anti-inflammatory and analgesic effects, does not affect normal body temperature, and has no obvious inhibitory effect on central nervous system. The latter is considered to be comparable to Atractylodes The basis for the difference. Recently, the effect of Atractylodes macrocephala on the spontaneous activity of isolated small intestine in rabbits is different. Atractylodes can enhance the spontaneous contraction of isolated small intestine of rabbits, and increase the contraction amplitude. Atractylodes oil inhibits the spontaneous movement of the intestine, or Atractylodes on rabbits. The spontaneous movement of the isolated small intestine is not obvious. Atractylodes macrocephala extract 50mg and 200mg/kg administered by gavage, the animal water immersion restraint stress ulcer, has a significant inhibitory effect. Large belly skin, Weixin; Slightly warm. Return to the spleen, stomach, large intestine, small intestine. Indications of gastrointestinal qi stagnation, abdominal distension, boring, stool is not good. The product can be scattered, the main spleen and stomach, can lead to qi stagnation, is a good medicine for wide and good gas. It can be used in conjunction with sputum, if it is swollen with acid, constipation or diarrhea. If the stagnation of the stagnation of the stagnation of the stomach is full, it can be used with patchouli, Chuanxiong and Magnolia. Equivalent. The ancient book "Japanese Huazi Materia Medica": Everything is qi, stop cholera, pass the large intestine, spleen appetite, tune. "Kai Bao Materia Medica": The main cold and hot gas attack confidant, large intestine poison, sputum, vinegar heart. And with ginger salt and fried, into the air-conditioning medicine. "Compendium": Reduce the gas, eliminate the swelling of the skin in the water, the athlete's foot hiccups, sputum malaria, fetal gas resistance and swelling. "Materia Medica renewed": diarrhea, and stomach, dampness and chasing wind, wide bowel swelling, waist and athlete's foot, cure malaria and diarrhea. Gange, sweet, spicy, cool, for the treatment of symptoms, attending exogenous fever, strong head pain, early onset of measles, poor rash, warm thirst, diabetes, diarrhea, dysentery, high blood pressure, Coronary heart disease. Atractylodes sinensis, generally rhizome is used as medicine for spleen medicine. It has a bitter and warm taste, and it has the effects of dampness, turbidity and pain relief. Atractylodes sinensis has the effect of dampness and spleen, and rheumatism. Indications of wet resistance in the coke, wind and cold dampness, swelling of the feet and knees, soft and weak, the eye blind night blind. "Pearl sac" Day: "Can strengthen the stomach and spleen, all wet and swollen can not be removed.""Compendium of Materia Medica" 曰: "Drug and sputum to drink... And the spleen is wet and down, the turbidity is taken down, and the intestines are slid. "The new revision of the herb" said that it can "poop" to adjust the function of gastrointestinal motility. Atractylodes decoction and atractylodes extract can significantly alleviate acetylcholine-induced small intestinal fistula in rabbits, while adrenaline Inhibition of small bowel movement has a certain antagonistic effect. Anti-ulcer: Atractylodes has a strong anti-ulcer effect. It has been found that Atractylodes lancea and Beifang acupuncture have pyloric ligation ulcers, pyloric ligation-aspirin ulcers, and stress ulcers. Strong inhibition, both kinds of Atractylodes can significantly inhibit ulcers, animal stomach fluid volume, total acidity, total digestive capacity and gastric mucosal damage. White peony, can calm the liver and relieve depression, hurricane eyesight. For liver yang dizziness headache Liver depression, hypochondriac pain, wind-heat headache, red eyes and swelling, skin itching and other symptoms. Cardamom is a perennial evergreen grass plant, producing Lingnan. Gaozhang Xu, looks like plantain, leaves large, lanceolate, yellowish flowers, It is firm in autumn, the fruit is spheroidal, and the seeds are like garnets. They can be used as medicine and have aroma. They can be used for dehumidification, temperature, appetizing and digestion. Do not think about diet, wet temperature, chest tightness, no hunger, cold and dampness, chest and abdomen pain, food can not be saved. 枳, bitter; Xin; cold. Return to the spleen, stomach, liver, heart. Fullness and pain; constipation; heavy after diarrhea; chest; stomach ptosis; uterine prolapse; rectal prolapse. Effect of tamping on gastrointestinal: sturdy, clam shell decoction, tincture and extract Rats and rabbits have inhibitory effects on the intestines of the intestines and rabbits. The decoction makes the stomach and the intestines The gastrointestinal contraction rhythm is powerful and excitatory, but inhibits the dog's gastrointestinal movement. The extract of citrus aurantium has obvious antagonistic effect on intestinal contraction caused by acetylcholine and histamine. Xiangfu can relieve qi, relieve menstruation and relieve pain; Main flank pain; breast swelling; hernia pain; irregular menstruation; abdomen full of pain; hernia gas, vomiting; abdominal pain; uterine bleeding; fetal movement. For liver qi stagnation, chest, flank, abdominal pain, indigestion, chest tightness, cold and abdominal pain, breast pain, irregular menstruation, menstrual dysmenorrhea. The effect of Xiangfu on the gastrointestinal tract: The isolated intestine of rabbits was prepared according to the conventional method, and the effect of volatile oil on the isolated intestinal tract was recorded by a smear drum. The results show that when the volatile oil concentration of Xiangfu is

At 5 μ g/ml, the contraction of the intestine can be inhibited. When the concentration is increased to 20 μg/ml, the inhibition is markedly reduced, and the intestinal contraction amplitude is decreased and the tension is decreased. Singh N also reported that when the concentration of scented alcohol extract was 20 μg/ml, it had a direct inhibitory effect on isolated rabbit ileum smooth muscle, treating qi and heart fullness, chest congestion, phlegm, and stomach stagnation. Vomiting and hangover are not solved, do not think about diet. Chuanxi Weixin, sexual temperature, liver, gallbladder, heart, qi and scent, with blood circulation, phlegm and pain relief, attending irregular menstruation, dysmenorrhea, amenorrhea, dystocia, cytoplasm, postpartum lochia, abdominal pain, lumps , heart and chest pain, bruises, swelling, pain, headache, dizziness, darkness, cold and wet, limb numbness, hemorrhoids. Orange peel, tender and slightly bitter, warm, into the spleen, lung. Rational air conditioning, dampness and phlegm effect, can be used to treat spleen and stomach qi stagnation, abdominal fullness, vomiting, or wet turbidity caused by chest tightness, poor appetite, sticky notes, but Yinjin loss, there is real heat Use, for spleen deficiency diet reduction, elimination Poor, and nausea and vomiting. The product is damp and spleen appetite, suitable for spleen and stomach weakness, diet reduction, indigestion, fecal diarrhea, etc., often with the application of Atractylodes, Poria and so on. Because it can not only strengthen the spleen, but also qi, it is often used as an adjunct to qi medicine, which can make up and not stagnate, and prevent sputum from suppressing swelling. Polygonum cuspidatum, slightly bitter, slightly cold. Liver, gallbladder, lung, rhizome for medicinal purposes, with blood circulation, dilated phlegm, menstruation, antitussive and other effects, can clear away heat and detoxification, spleen and yellow, phlegm and dampness, dilated and painful, cough sputum. For joint pain, damp heat jaundice, amenorrhea, postpartum blood stasis, symptoms, cough, water and fire burns, bruises, bruises and sores. Yuanhu, a poppy plant, is used as a tuber, and has the effect of promoting blood circulation and dispersing phlegm, regulating qi and relieving pain, treating stomach pain, dysmenorrhea, bruises, etc. It is spicy, bitter, and warm. It has the function of activating blood circulation, relieving pain and relieving pain. It is used for all kinds of qi stagnation and blood stasis pain, dysmenorrhea, amenorrhea, symptoms, postpartum stagnation, falling and dying, and suffocating. Coix seed, cool, sweet, light, is the seed of the grass family. Have spleen and spleen, remove phlegm and diarrhea. It is used for edema, athlete's foot, unfavorable urination, phlegm and blood stasis, spleen deficiency and diarrhea. Indications: spleen and spleen, remove phlegm and diarrhea. For edema, athlete's foot, dysuria, phlegm and blood stasis, spleen diarrhea. Astragalus, Astragalus, alias Camellia root, earth tea root. For the plant of the Labiatae, the root is used as a medicine. It has heat and dampness, cool blood and fetus, detoxification effect. Indications for warm disease, upper respiratory tract infection, lung heat cough, damp heat yellow biliary, pneumonia, dysentery, hemoptysis, red eyes, fetal dysphoria, high blood pressure, carbuncles and hemorrhoids. The clinical application of Astragalus is better than that of Coptis, and it does not produce drug resistance. Big blood vine, bitter, flat. Return to the large intestine and liver. Indications: Detoxification, blood circulation, hurricane. For intestinal pain, abdominal pain, menstrual dysmenorrhea, rheumatism, pain, swelling and swelling. It has the functions of detoxification, promoting blood circulation and collaterals, and killing insects. Emergency treatment, chronic appendicitis, rheumatic pain, red sputum, bloody, irregular menstruation, hoarding, insect pain, fall damage and other symptoms. White peony, cold, bitter, sweet, sputum, non-toxic; return to the lungs, stomach, liver. It has the function of astringent hemostasis, swelling and muscle growth. Indications for pulmonary sputum, blood vomiting, blood stasis, blood in the stool, traumatic bleeding, hemorrhoids, sputum, sputum, burns, hand and foot cleft palate, anal fissure and other diseases. In combination with other traditional Chinese medicines of the invention, the effect of treating gastritis is obvious. Millet, is the grain of the shell of Setaria ital ica, because of its small size, about 1 mm in diameter, hence the name. Originally produced in the Yellow River Basin in northern China, the main food crops in ancient China, so the Xia Dynasty and the Shang Dynasty belonged to the "Sui Culture". Millet is drought-tolerant and has a wide variety. It is commonly known as "Sui has colorful". Xiaomi is cool and sweet, can stop vomiting, nourish the stomach, laxative, stop venting, nourishing blood and qi, spleen, hypoglycemic and thirst, nourishing yin Tonic, has a good conditioning and nourishing effect on the gastrointestinal tract: Indications of dyspepsia: B vitamins can promote the secretion of digestive juice, maintain and promote intestinal peristalsis, is conducive to bowel movements. And the effect of sores in the mouth, and stomach: neutralize stomach acid, relieve stomach pain. Millet has the effect of preventing pancreatic stomach and vomiting. From the perspective of traditional Chinese medicine, the etiology and pathogenesis of chronic gastritis, there are diets, bruises in Zhongzhou, or exogenous evils, damage to the spleen and stomach, or worry about anger, liver loss, diarrhea, and lack of endowment The spleen and stomach are weak, and the disease is in the "stomach", but it is closely related to the "spleen", "liver" and "kidney". The pathogenesis is characterized by the virtual medium. Therefore, the above traditional Chinese medicine compatibility and preparation method by the present invention The obtained composition is validated by a dialectical method To the effect of conditioning the stomach and the internal organs, no toxic side effects, stable effect, compared with Western medicine to achieve twice the result with half the effort. Clinical Experiment 1:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the period of 6 months from March 2013 to August 2013 is selected.

2), Observation object: 10 cases of chronic gastritis were selected in the Department of Gastroenterology, Shenzhen Hospital of Guangdong Province: 6 males and 4 females; age: 5 cases of 40-55 years old, 5 cases of 60-75 years old; Occupation: General work There are 5 families and 5 retirees. Symptoms: After a meal, fullness, pantothenic acid, no regular abdominal pain and other symptoms.

3), How to use: The oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.

4), observation effect:

After taking 3 courses in a row, 6 cases of symptoms such as fullness after meals, pantothenic acid, irregular abdominal pain, etc., a little fullness after meals, mild pantothenic acid, irregular mild abdominal pain and other symptoms are basically no longer In 2 cases, 2 cases of postprandial fullness, pantothenic acid, and irregular abdominal pain were not obvious, and the total effective rate was 80%.

Clinical trial 2:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the six months from April 2013 to September 2013 are selected.

2), Observed subjects: 20 cases were selected in the Department of Gastroenterology, Futian District Hospital of Shenzhen, Guangdong Province: 12 males and 8 females; age: 10 cases of 32-55 years old, 10 cases of 56-75 years old; Occupation: 10 cases of civil servants in leadership positions and 10 cases of ordinary teachers. Symptoms: upper abdominal discomfort, pain, indigestion, vomiting, disgusting nausea, etc.

4), observation effect:

After three consecutive courses of treatment, the patient's original abdominal pain, indigestion has disappeared, vomiting, hiccups and nausea are no longer appearing in 12 cases, mild abdominal pain and indigestion, occasional mild vomiting, hiccups and nausea in 3 cases Abdominal pain, indigestion has disappeared, vomiting, hiccups and nausea improved in 5 cases, the total effective rate is 75%.

Clinical Trial 3:

1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the time period from July 2013 to December 2013 is selected.

2), Observed subjects: 30 cases were selected in the Department of Gastroenterology, Songgang People's Hospital, Shenzhen, Guangdong Province: 12 males and 18 females; Age: 16 cases of 35-55 years old, 14 cases of 60-75 years old; Occupation: Ordinary private enterprise There are 14 main cases and 16 ordinary retired teachers. Symptoms: fullness after meals, pantothenic acid, irregular abdominal pain, upper abdominal discomfort, pain, indigestion, vomiting, disgusting

4), observation effect:

After taking 3 courses in a row, the patient's original abdominal pain, indigestion has disappeared, vomiting, hiccups and nausea are basically no longer appearing in 18 cases, mild abdominal pain and elimination 6 cases of dysplasia, occasional mild vomiting, hiccups and nausea, abdominal pain, indigestion, vomiting, hiccup and nausea were not obvious, and the total effective rate was 80%. Combined with the above clinical data and the theoretical basis of the present invention, it can be seen that the preparation prepared by the invention has good effects for treating chronic gastritis, and is non-toxic, has no side effects, and has stable effects, and the preparation process is simple and easy. Concrete real

The present invention will be described in detail below with reference to the embodiments:

Example 1:

The preparation of the invention is made up of patchouli, perilla leaf, atractylodes, big belly skin, gange, atractylodes, white peony, cardamom, medlar, fragrant, chuanxiong, orange peel, polygonum cuspidatum, yuanhu, coix seed, jaundice, A preparation of a composition prepared from the spatholobus, white peony and millet, wherein the mass ratio of each component is:

Patchouli 12g Perilla Leaf 10g Atractylodes lOg Big belly skin 12g Gange 12g Atractylodes 15g White peony 10g Cardamom 12g 枳 8 8g

Fragrant 15g Chuanxiong 15g orange peel 13g

Polygonum cuspidatum 12g Yuanhu 8g 薏苡仁 10g 黄芩 12g 大血藤 13g 白芨 10g

Millet lGg.

The above preparation method for treating traditional Chinese medicine for chronic gastritis includes the following steps: 1), the perilla leaves are placed in a small pot for small frying until the surface is slightly coke, and then crushed by a pulverizer and passed through a 80 mesh sieve for use;

2), the patchouli, atractylodes, abdomen, gane, white peony, cardamom, medlar, millet, scutellaria, big blood vine are proportioned well, pulverized into powder through a pulverizer and passed through a 90 mesh sieve, natural Dry, spare;

3), mix the powders of each component in steps 1) and 2), add boiling water twice, add 8 times pure water for 1 hour, simmer for 1 hour, and add 4 times for the second time. Decoction in pure water for half an hour, then combine the decoction and filter, set aside;

6), the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to the combined decoction in the step 3), and mixed and shaken to obtain.

The preparation of the above-mentioned traditional Chinese medicine composition solution can be used for oral administration, and if it can be consumed once in the morning and evening and long-term drinking, the effect is better.

Example 2:

The preferred raw material quality of the present invention is (g): Patchouli 12g basil leaves 10g Atractylodes 12g 10g Arecae Ge Gan 12 _g herb Tribulus terrestris 10g 15g 12g cardamom citrus aurantium Cyperus 15g 10g Chuanxiong

13g Polygonum cuspidatum 12g Yuanhu 8g Coix seed 10g Astragalus 12g Big blood vine 13g White peony 10g Millet 16g.

The preparation method is as in Example 1.

Example 3;

The preferred raw material quality of the present invention is (g):

Patchouli 15g Perilla Leaf 12g Atractylodes 9g Big belly skin 15g Gange 10g Atractylodes

I 12g Soybean meal 10g 枳香 12g Chuanxiong 11⁄2 orange peel Polygonum cuspidatum 8g Yuanhu 8g Huanren Astragalus 10g Big blood vine 8g White peony 10g Millet 15g.

The preparation method is as in Example 1.

Example 4:

The preferred raw material quality of the present invention is (g):

Patchouli 18g Perilla Leaf 15g Atractylodes 12g

16g Gange 12g Atractylodes 15g White peony 13g Soybean meal 15g 枳 12 12g 香香 16g Chuanxiong 14g orange peel 16g Polygonum cuspidatum 10g Yuanhu 12g 薏苡^ ί 15g Yellow zero 16g Big blood vine 13g 12g Millet 18g.

The preparation method is as in Example 1.

Example 5

The preferred raw material quality of the present invention is (g):

Patchouli 16g Perilla Leaf 18g Atractylodes 15g Big belly skin 14g Gange 15g Atractylodes 18g White medicine 藜15g Bean curd 18g 枳 14g 香香18g Chuanxiong 16g Orange peel 14g Polygonum cuspidatum 12g Yuanhu 13g Coix seed: 13 Astragalus 18g Big blood vine 15g White peony 15g millet 18g.

The preparation method is as in Example 1.

Example 6:

The preferred raw material quality of the present invention is (g)

Patchouli 15g Perilla Leaf 18g Atractylodes 15g Big belly skin 16g Gange 15g Atractylodes 20g White peony 12g Soybean meal 20g 枳 16g 香附16g Chuanxiong 18g Orange peel 15g Polygonum cuspidatum 15g Yuanhu 15g Coix seed 12g Astragalus 16g Big blood vine 16g White peony 13g Millet 20g.

The preparation method is as in Example 1.

The above embodiments are only a few of the various embodiments of the present invention. For example, if the formula is increased or decreased according to the ratio in the technical solution, the therapeutic effect of the preparation of the chronic gastritis preparation is not affected, and will also fall. It is within the scope of the claims of the present invention.

Claims

Rights request

1. A traditional Chinese medicine for treating chronic gastritis, characterized in that the preparation of the present invention is composed of Patchouli, Perilla leaves, Atractylodes, Dabupi, Gan Ge, Atractylodes, Tribulus terrestris, cardamom, Citrus aurantium, Fu, Ligusticum chuanxiong, Tangerine A composition preparation prepared from bark, Polygonum cuspidatum, Yuanhu, Coix seed, Scutellaria baicalensis, Bloodvine, Bletilla striata and millet: the mass ratio of each component is:

Patchouli 12-20g Perilla leaves 10-22g Atractylodes macrocephala 8-18g Dabupi 10-18g Gan Ge 8-15g Atractylodes macrocephala

10-20g

Tribulus terrestris 8-16g Cardamom 12-20g Citrus aurantium 8-16g Cyperus cyperus 10_18g Chuanxiong 10-18g Orange peel

10-18g

Polygonum cuspidatum 8-15g Yuanhu 6-15g Coix seed

8-15g

Scutellaria baicalensis 10- 18g, Scutellaria baicalensis 8-16g, Bletilla 8-15g, millet 10- 20g.

2. The traditional Chinese medicine for treating chronic gastritis according to claim 1, further characterized in that the mass ratio of each component is

Patchouli 12-18g Perilla leaf 10-18g Atractylodes macrocephala

8-12g

Big Belly Skin 12-18g Gan Ge 8-12g Atractylodes Atractylodes

10-15g

White Tribulus 8-12g Cardamom 12-16g Citrus aurantium 8-12g

Cyperus cyperus 10-15g Chuanxiong 10-14g

10-15g

Polygonum cuspidatum 8-12g Yuanhu 6-10 _g

8-12g

Scutellaria baicalensis 10-15g Bloodvine 8-12g Bletilla striata

8-12g

Xiaomi 12-18g.

3. The traditional Chinese medicine for treating chronic gastritis according to claim 1 or 2, further characterized in that the mass ratio of each component is:

Patchouli 15g Perilla leaves 12g Atractylodes 9g Big belly peel 15g Gan Ge 10g Atractylodes 12g Tribulus 12g Cardamom 10g Citrus aurantium 8g Cyperus 12g Ligusticum chuanxiong 14g Orange peel 12g

Polygonum cuspidatum 8g, Yuanhu 8g, Coix seed 12g, Scutellaria baicalensis 10g: Blood Vine 8g, Bletilla 10g

Xiaomi 15g.

4. A preparation method of traditional Chinese medicine for treating chronic gastritis, which is characterized in that it includes the following steps:

1). Put the perilla leaves into a small pot and fry until the surface is slightly charred, then crush it with a grinder and pass through an 80-mesh sieve, and set aside;

2). Add patchouli, Atractylodes, Dabupi, Kudzu, Tribulus terrestris, cardamom, Fructus aurantium, Fructus aurantium. Rice, skullcap, and bloodvine are mixed in proportion, crushed into powder by a grinder, passed through a 90-mesh sieve, and dried naturally for later use;

3). Mix the powders of each component in steps 1) and 2) together, add purified water and cook twice. For the first time, add 10 times purified water and cook over low heat for 1 hour. Extract the filtrate and set aside. Add 6 times purified water at a time and simmer over low heat for half an hour, then combine the decoction and filter, set aside;

4). Mix the remaining Atractylodes rhizome, Cyperus rotundus, Ligusticum chuanxiong, orange peel, Polygonum cuspidatum, Yuanhu, coix seed, and Bletilla striata in proportion, grind them into powder through a crusher and pass through an 80-mesh sieve, dry naturally and set aside;

5). Mix the powders of each component in step 4) together, add 4 to 6 times of 70% to 80% ethanol, heat and reflux for 3 to 5 hours, extract and filter to obtain the filtrate; then add the remaining medicinal residue. Add 2 to 4 times of 65% to 75% ethanol again, heat and reflux for 2 to 3 hours, extract and filter to obtain the filtrate; combine the two filtrate obtained together, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste. ;

6). Ultrafinely pulverize the dry paste obtained in the above step 5) into powder and pass it through a 200 mesh sieve. Then add the powder to the combined decoction in step 3), mix and shake well to prepare. The prepared above-mentioned Chinese medicine composition solution preparation can be taken orally. If it can be drunk once in the morning, noon and evening in an appropriate amount and for a long time, the effect will be better.