WO2015149394A1 - Traditional chinese medicine oral liquid for treating chronic gastritis - Google Patents
Traditional chinese medicine oral liquid for treating chronic gastritis Download PDFInfo
- Publication number
- WO2015149394A1 WO2015149394A1 PCT/CN2014/075341 CN2014075341W WO2015149394A1 WO 2015149394 A1 WO2015149394 A1 WO 2015149394A1 CN 2014075341 W CN2014075341 W CN 2014075341W WO 2015149394 A1 WO2015149394 A1 WO 2015149394A1
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- WIPO (PCT)
- Prior art keywords
- chinese medicine
- add
- forsythia
- chronic gastritis
- bupleurum
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Definitions
- the invention relates to a traditional Chinese medicine oral liquid for treating chronic gastritis, and particularly relates to the traditional Chinese medicine oral liquid for treating chronic gastritis and a preparation method thereof.
- Chronic gastritis refers to chronic inflammation of the gastric mucosa caused by different causes. The essence is that the gastric mucosal epithelium suffers repeated damage, leading to mucosal remodeling, which eventually leads to irreversible atrophy or disappearance of the intrinsic gastric gland. Chronic gastritis is often accompanied by a certain degree of atrophy (visual membrane loss) and decreased secretion of gastrin. The clinical symptoms are mainly symptoms of upper abdominal pain or discomfort, fullness, belching, nausea, and indigestion. The etiology of chronic gastritis in modern medicine has not been fully elucidated and may be related to factors such as improper diet, malnutrition, tissue congestion and hypoxia.
- the object of the present invention is to provide a traditional Chinese medicine oral liquid for treating chronic gastritis based on the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and specifically to provide such a Chinese medicine oral liquid and a preparation method thereof.
- the invention has obvious therapeutic effects on gastritis, and is non-toxic, has no side effects, and has stable effects, and the preparation process is simple and easy.
- the technical solution of the present invention is as follows:
- the preparation of the invention is composed of musk, hexagram, white lentils, forsythia, medlar, lycopene, Bupleurum, Zhuru, cinnamon, Amomum vulgaris, woody, Jiaoshan, fried malt, berberine, coix seed, scutellaria, Cistanche , a preparation of a composition prepared from white peony and millet, wherein the mass ratio of each component is:
- the preferred raw material quality ratio of the present invention is: Musk 12_18g Liuqu 10-18g White lentils 8-12g Forsythia 12-18g ⁇ 8-12g Laiwuzi
- the present invention can also be used as a preferred raw material quality i. 15g hexa 12g white lentils 9g forsythia 15g ⁇ 10g laizi 12g bupleurum 12g bamboo rug 10g cinnamon 8g
- the above preparation method for treating a chronic gastritis Chinese medicine oral liquid comprises the following steps:
- step 3 mix the powders of each component in step 1) and 2), add boiling water twice, add 10 times pure water for 1 hour, extract the filtrate for use; 6 times pure water decoction for half an hour, then combine the decoction and filter, spare;
- step 5 mixing the powders of each component in step 4), adding 4 to 6 times 70% ⁇ 80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;
- the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200-sieving sieve, and then the powder is added to 3) the combined decoction in the step, and the mixture is shaken to obtain.
- the preparation of the above traditional Chinese medicine composition solution can be used for oral administration, and if it can be consumed once in the morning and evening, and consumed for a long time, the effect is better.
- the theoretical basis of the invention lies in: musk, sexually lukewarm, sweet and sour, with aromatization and wetness, publication of heat, dispelling evil, dehumidification and detoxification, clearing heat and quenching thirst, and stomach vomiting, fast gas and medium, Good stomach and dampness and other effects.
- Jiaoliuqu, sweet, spicy, warm can be digested, stomach, used for indigestion, bloating, diarrhea, this product is made of almond puree, red bean, spicy sedge, artemisia, flour, eclipse
- the processed product obtained by fermentation after mixing has the effect of regulating blood stasis, dissatisfaction of stomach and stomach, inability to eat, gluttony, weak limbs, and a variety of diseases.
- the pharmacological action of white lentils in the preparation of the present invention is mainly antibacterial, antiviral, experimental table Ming: 100% white lentils decoction using plate paper method, has an inhibitory effect on dysentery bacilli; has detoxification effect on vomiting caused by food poisoning, acute gastroenteritis.
- the Columbia SK virus has an inhibitory effect.
- Forsythia bitter taste, slightly cold, is the genus Forsythia genus, forsythia early flowering in early spring, flower aroma is light, full of golden, colorful and delicious, is a good early spring flowering shrub, the fruit can be used as medicine.
- Forsythia mainly contains phenylethanoid glycosides, lignans and their glycosides, pentacyclic triterpenes, and volatile oils. Pharmacological studies believe that it has antibacterial, anti-inflammatory, antipyretic, antiemetic, diuretic, anti-liver, analgesic, inhibition of phosphodiesterase, anti-virus, blood pressure lowering, inhibition of amylase activity, anti-endotoxin and so on.
- Forsythia has antibacterial, cardiotonic, diuretic, antitussive and other pharmacological effects. It is a traditional Chinese medicine for clearing away heat and detoxification. It treats fever, fever, fever, upset, sore throat, acute nephritis, swollen sore and other symptoms. Its antibacterial effect is similar to that of honeysuckle.
- the main ingredient in sputum is ubiquitin, which is high in content. It has inhibitory effect on various bacteria; it can lower stomach acid and has preventive effect on digestive tract ulcer; It has obvious protective effect on liver injury; It has anti-tumor effect; It can regulate immune function in many aspects; It can make leukocytes caused by chemotherapy Reduce the acceleration and recovery; and have a calming effect.
- Zhuru sweet, slightly cold, into the lungs, stomach, gallbladder, attending to clear away heat and phlegm, in addition to annoying vomiting. It is used for hot cough, biliary phlegm, irritability, vomiting, convulsions, eye loss, strong tongue, strong tongue, stomach vomiting, pregnancy resistance, fetal movement. This product is good at phlegm and phlegm, clearing away heat and removing troubles. It is suitable for hot cough, stomach heat vomiting, phlegm and irritability, etc. It can also be used for cooling blood and fetus, for fetal movement, and is a cure for stomach heat and stomach vomiting. Good medicine.
- Cinnamon can make Yuanyang, warm the spleen and stomach, in addition to cold, blood circulation.
- the rule of life is dying, the limbs are cold, the yang is collapsed, the abdominal pain is diarrhea, the cold sputum is porpoise, the waist and knees are cold and painful, the syndrome is closed, the haze, the flow, and the virtual yang are floating.
- Cinnamon powder warm water delivery service can treat stomach bloating, stomach cold pain; adding cinnamon skin powder to the dish to cook, can help control blood sugar and cholesterol.
- Amomum sin, warm, spleen, stomach, kidney. It can be wet appetizer, warm spleen and diarrhea, qi and amphibious, often used in wet turbidity, hunger, spleen and stomach, vomiting and diarrhea, pregnancy dysfunction, fetal movement. Amomum can warm the stomach to warm up the stomach to relieve vomiting and diarrhea, but it focuses on warming the spleen.
- Chinese medicine as a spleen and stomach qi stagnation, abdominal distension or pain, belching, nausea and vomiting.
- Jiaoshan ⁇ is taken from the net hawthorn, fried according to the method of frying until the surface is brown, and the interior is yellowish brown. This product is shaped like a hawthorn slice with a brownish surface and a yellowish interior.
- aroma of coke Sour, sweet, slightly warm, spleen, stomach, liver. You can digest your stomach and divert your stomach. For meat stagnation, stomach cramps fullness, diarrhea, abdominal pain, blood stasis, postpartum obstruction, heart and abdomen pain, hernia pain; hyperlipidemia. The effect of Jiaoshan ⁇ digestion on food is enhanced. It is used for stagnant meat, and it is not good for diarrhea.
- Coptis can clear away heat and dampness, purging fire and detoxification.
- damp heat vomiting, vomiting, diarrhea, jaundice, high fever, dizziness, heartburn, upset, bloody vomiting, redness, toothache, thirst, carbuncles and hemorrhoids; external treatment of eczema, Wet sores, pus in the ear canal. Liquor and yellow are good on the fire.
- eye red mouth sores.
- Turmeric even clears the stomach and stomach to vomit.
- For liver and stomach disharmony, vomiting and acid. This product can also relieve liver and relieve stagnation, and is used for liver qi stagnation or hypochondriac pain of liver and stomach, abdominal pain, etc. It can be used together with other liver-relieving qi drugs.
- Coix seed cool, sweet, light
- spleen and spleen remove phlegm and diarrhea. It is used for edema, athlete's foot, unfavorable urination, phlegm and blood stasis, spleen deficiency and diarrhea. Indications: spleen and spleen, remove phlegm and diarrhea. For edema, athlete's foot, urinary, Wet sputum, spleen diarrhea.
- Astragalus alias Camellia root, earth tea root.
- the root is used as a medicine. It has heat and dampness, cool blood and fetus, detoxification effect. Indications for warm disease, upper respiratory tract infection, lung heat cough, damp heat jaundice, pneumonia, dysentery, hemoptysis, red eyes, fetal dysphoria, high blood pressure, bloated hemorrhoids embolism.
- the clinical application of Astragalus is better than berberine and does not produce drug resistance.
- Cistanche sweet, salty, warm. Return to the kidney, large intestine, can replenish kidney yang, benefit essence blood, run the bowel. For impotence, infertility, weak waist and knees, weak bones, constipation.
- composition obtained by the preparation method can effectively achieve the effect of regulating the stomach and the internal organs by using a dialectical method, has no toxic and side effects, and has stable effects, and achieves twice the result with half the effort compared with the western medicine.
- the oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.
- the oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.
- the oral liquid of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for 1 course of treatment, and 3 courses of treatment as therapeutic effects. 4), observation effect:
- the preparation prepared by the present invention has good effects for treating chronic gastritis, is non-toxic, has no side effects, has stable effects, and is simple and easy to prepare.
- the preparation of the invention is composed of musk, hexagram, white lentils, forsythia, medlar, lycopene, Bupleurum, Zhuru, cinnamon, Amomum vulgaris, woody, Jiaoshan, fried malt, berberine, coix seed, scutellaria, Cistanche , a preparation of a composition prepared from white peony and millet, wherein the mass ratio of each component is:
- the above preparation method for treating a chronic gastritis Chinese medicine oral liquid comprises the following steps:
- step 5 mixing the powders of each component in step 4), adding 4 to 6 times 70% ⁇ 80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;
- the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to the combined decoction in the step 3), and mixed and shaken to obtain.
- the prepared Chinese medicine composition solution preparation can be used for oral administration, if it can be early, middle and late Drinking once and drinking for a long time, the effect is better.
- the preferred raw material quality of the present invention is (g):
- the preparation method is as in Example 1.
- the preferred raw material quality of the present invention is (g):
- Example 4 The preferred raw material quality of the present invention is (g):
- the preparation method is as in Example 1.
- the preferred raw material quality of the present invention is (g):
- the preparation method is as in Example 1.
- the preferred raw material quality of the present invention is (g):
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Abstract
Traditional Chinese medicine oral liquid for treating chronic gastritis, the preparation comprising Agastache rugosa, medicated leaven, semen lablab album, fructus forsythiae, Wolfiporia extensa, semen raphani, radix bupleuri, Bambusa tuldoides Munro, cinnamon, Amomum villosum, common vladimiria root, charred Crataegus pinnatifida Bunge, parched barley, Coptis chinensis, Coix lacryma-jobi, Scutellaria baicalensis, Cistanche deserticola, Bletilla striata, and Setaria italica.
Description
一种治疗慢性胃炎的中药口服液 技术领域 Traditional Chinese medicine oral liquid for treating chronic gastritis
本发明涉及一种治疗慢性胃炎的中药口服液,具体涉及这种治疗 慢性胃炎的中药口服液及其制备方法。 背景技术 The invention relates to a traditional Chinese medicine oral liquid for treating chronic gastritis, and particularly relates to the traditional Chinese medicine oral liquid for treating chronic gastritis and a preparation method thereof. Background technique
慢性胃炎, 是指由不同的病因引起的胃粘膜的慢性炎症, 其实质 是胃粘膜上皮遭受反复损害后, 导致粘膜发生改建, 最终导致不可逆 的固有胃腺体的萎缩,甚至消失。慢性胃炎常伴有一定程度的萎缩 (粘 膜丧失功能) 和胃泌素分泌减少,临床症状主要表现为上腹疼痛或不 适、 饱胀、 嗳气、 恶心、 消化不良等症状。 现代医学对慢性胃炎的病 因尚未完全阐明, 认为可能与饮食不当、 营养不良、 组织淤血和缺氧 等因素有关。目前,患者通常服用西药来治疗,但是西药治标不治本, 只能暂时缓解症状, 并不能根除病根, 而且在治疗胃炎的同时, 还往 往会伤及肝肾等器官, 疗效不稳定, 容易复发。 发明内容 Chronic gastritis refers to chronic inflammation of the gastric mucosa caused by different causes. The essence is that the gastric mucosal epithelium suffers repeated damage, leading to mucosal remodeling, which eventually leads to irreversible atrophy or disappearance of the intrinsic gastric gland. Chronic gastritis is often accompanied by a certain degree of atrophy (visual membrane loss) and decreased secretion of gastrin. The clinical symptoms are mainly symptoms of upper abdominal pain or discomfort, fullness, belching, nausea, and indigestion. The etiology of chronic gastritis in modern medicine has not been fully elucidated and may be related to factors such as improper diet, malnutrition, tissue congestion and hypoxia. At present, patients usually take Western medicine to treat, but Western medicine can not cure the symptoms, can only temporarily relieve the symptoms, and can not eradicate the roots, and in the treatment of gastritis, it will often hurt the liver and kidney and other organs, the effect is unstable, easy to relapse. Summary of the invention
本发明的目的即在于针对上述不足, 在祖传秘方的基础上, 结合 现代中西医技术, 提供一种治疗慢性胃炎的中药口服液, 具体的说是 提供这种中药口服液及其制备方法, 本发明胃炎治疗效果明显, 而且 无毒, 无副作用, 效果稳定, 制取工艺简便易行。
本发明的技术方案如下所述: The object of the present invention is to provide a traditional Chinese medicine oral liquid for treating chronic gastritis based on the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and specifically to provide such a Chinese medicine oral liquid and a preparation method thereof. The invention has obvious therapeutic effects on gastritis, and is non-toxic, has no side effects, and has stable effects, and the preparation process is simple and easy. The technical solution of the present invention is as follows:
本发明制剂是由藿香、 六曲、 白扁豆、 连翘、 茯苓、 莱菔子、 柴 胡、 竹茹、 肉桂、 砂仁、 木香、 焦山楂、 炒麦芽、 黄连、 薏苡仁、 黄 芩、 肉苁蓉、 白芨和小米制备成的组合物制剂, 其中各组分的质量配 比为: The preparation of the invention is composed of musk, hexagram, white lentils, forsythia, medlar, lycopene, Bupleurum, Zhuru, cinnamon, Amomum vulgaris, woody, Jiaoshan, fried malt, berberine, coix seed, scutellaria, Cistanche , a preparation of a composition prepared from white peony and millet, wherein the mass ratio of each component is:
藿香 12-20g 六曲 10-22g 8- 18g 连翘 10-18g 茯苓 8-15g 莱菔子 Musk 12-20g Liuqu 10-22g 8- 18g Forsythia 10-18g 茯苓 8-15g Lai Zizi
10- 20g 10- 20g
柴胡 8-16g 竹茹 12-20g 8- 16g 砂仁 10-18g 木香 10-18g 焦山楂 Bupleurum 8-16g Zhuru 12-20g 8- 16g Amomum 10-18g Woody 10-18g Jiaoshan
10- 18g 10- 18g
炒麦芽 8-15g 黄连 6-15g 薏苡仁 Stir-fried malt 8-15g berberine 6-15g hazelnut
8-15g 8-15g
黄芩 10-18g 肉苁蓉 8-16g 8-15g 小米 10-20g。 Astragalus 10-18g Cistanche 8-16g 8-15g Millet 10-20g.
为了获得更好的效果, 本发明可优选的原料质量配比为: 藿香 12_18g 六曲 10-18g 白扁豆 8-12g 连翘 12-18g 茯苓 8-12g 莱菔子 In order to obtain better effects, the preferred raw material quality ratio of the present invention is: Musk 12_18g Liuqu 10-18g White lentils 8-12g Forsythia 12-18g 茯苓 8-12g Laiwuzi
10-15g 10-15g
柴胡 8-12g 竹茹 12-16g 肉桂 8-12g 砂仁 10-15g 木香 10- 14g 焦山楂 Bupleurum 8-12g Bamboo Ru 12-16g Cinnamon 8-12g Amomum 10-15g Woody 10- 14g Jiaoshan
10-15g
炒麦芽 8-12g 黄连 6-10g 薏苡仁 8-12g 黄芩 10-15g 肉苁蓉 8-12g
8-12g 小米 12-18g。 10-15g Stir-fried malt 8-12g Coptis 6-10g Coix seed 8-12g Astragalus 10-15g Cistanche 8-12g 8-12g millet 12-18g.
当然, 为了获得进一歩好的效果, 本发明还可优选的原料质 i香 15g 六曲 12g 白扁豆 9g 连翘 15g 茯苓 10g 莱菔子 12g 柴胡 12g 竹茹 10g 肉桂 8g Of course, in order to obtain a better effect, the present invention can also be used as a preferred raw material quality i. 15g hexa 12g white lentils 9g forsythia 15g 茯苓 10g laizi 12g bupleurum 12g bamboo rug 10g cinnamon 8g
砂仁 12g 木香 14g 焦山楂 12g 炒麦芽 8g 黄连 8g 薏苡仁 12g 黄芩 10g 肉苁蓉 8g 白芨 10g 小米 15g。 Amomum 12g woody 14g Jiaoshanyu 12g fried malt 8g berberine 8g hazelnut 12g jaundice 10g Cistanche 8g white peony 10g millet 15g.
上述治疗慢性胃炎中药口服液的制备方法, 包括如下歩骤: The above preparation method for treating a chronic gastritis Chinese medicine oral liquid comprises the following steps:
1 )、将六曲放入小锅进行小炒 2-3分钟, 然后经粉碎机粉碎并过 80目筛, 备用; 1), put the six songs into a small pot for small 2-3 minutes, then crushed by a pulverizer and passed through a 80 mesh sieve, ready for use;
2 )、 将藿香、 白扁豆、 连翘、 茯苓、 柴胡、 竹茹、 肉桂、 小米、 黄芩、 肉苁蓉按比例配好, 经过粉碎机粉碎成粉末并过 90 目筛, 自 然晾干, 备用; 2), the musk, white lentils, forsythia, medlar, Bupleurum, bamboo, cinnamon, millet, scutellaria, cistanche are proportioned, crushed into powder by a pulverizer and passed through a 90 mesh sieve, naturally dried, spare ;
3 )、 将歩骤 1 ) 和 2 ) 中的各组分粉末混合在一起, 加入纯净水 煎煮两次, 第一次加入 10倍纯净水煎煮 1小时, 提取滤液备用; 第 二次加入 6倍纯净水煎煮半小时, 然后合并煎液并过滤, 备用; 3), mix the powders of each component in step 1) and 2), add boiling water twice, add 10 times pure water for 1 hour, extract the filtrate for use; 6 times pure water decoction for half an hour, then combine the decoction and filter, spare;
4)、 将剩下的莱菔子、 砂仁、 木香、 焦山楂、 炒麦芽、 黄连、 薏
苡仁、 白芨按比例配好, 经过粉碎机粉碎成粉末并过 80 目筛, 自然 晾干, 备用; 4), the remaining Laizi, Amomum, Woody, Jiaoshan, Fried Malt, Coptis, Poria Coix seed and white peony are proportioned well, pulverized into powder after crushing machine and passed through 80 mesh sieve, naturally dried and used;
5 )、 将歩骤 4 ) 中各组分粉末混合在一起, 加入 4〜6倍70%〜80% 的乙醇, 加热回流 3〜5个小时, 提取过滤获得滤液; 然后在剩下的药 渣中再次加入 2〜4倍65%〜75%的乙醇, 加热回流 2〜3个小时, 提取过 滤获得滤液;将两次获得的滤液合并在一起,减压浓缩除去乙醇溶剂, 干燥, 获得干膏; 5), mixing the powders of each component in step 4), adding 4 to 6 times 70%~80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;
6 )、 将上述歩骤 5 ) 中获得的干膏进行超微粉碎成粉末并过 200 木筛, 然后将粉末加入 3 ) 歩骤中的合并煎液, 混合摇匀即可制得。 6), the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200-sieving sieve, and then the powder is added to 3) the combined decoction in the step, and the mixture is shaken to obtain.
制取的上述中药组合物溶液制剂可以用于口服,如果能够早中晚 各适量饮用一次并长期饮用, 效果更好。 本发明的理论依据在于: 藿香, 性微温, 味辛甘, 具有芳香化湿、 发表解暑、 解表散邪、 利湿除风、 清热止渴、 和胃止呕、 快气和中、 健胃祛湿等功效。 一般 用于治疗头痛发热、 风寒感冒、 胸闷腹胀、 胃寒疼痛、 呕吐、 泻痢、 口臭等症。 The preparation of the above traditional Chinese medicine composition solution can be used for oral administration, and if it can be consumed once in the morning and evening, and consumed for a long time, the effect is better. The theoretical basis of the invention lies in: musk, sexually lukewarm, sweet and sour, with aromatization and wetness, publication of heat, dispelling evil, dehumidification and detoxification, clearing heat and quenching thirst, and stomach vomiting, fast gas and medium, Good stomach and dampness and other effects. Generally used for the treatment of headache fever, cold, cold, chest tightness, bloating, stomach pain, vomiting, diarrhea, bad breath and other symptoms.
焦六曲, 味甘、 辛, 性温, 可以消食, 健胃, 用于消化不良, 食 积腹胀, 腹泻, 本品为采用杏仁泥、 赤小豆、 辣寥草、 青蒿、 面粉、 苍耳草药末混合后经发酵而成的加工品,在本发明中起到调理气血衰 弱, 胃气不和, 不能饮食, 食辄不消, 四肢旭弱, 百疾交攻的作用。 Jiaoliuqu, sweet, spicy, warm, can be digested, stomach, used for indigestion, bloating, diarrhea, this product is made of almond puree, red bean, spicy sedge, artemisia, flour, eclipse The processed product obtained by fermentation after mixing has the effect of regulating blood stasis, dissatisfaction of stomach and stomach, inability to eat, gluttony, weak limbs, and a variety of diseases.
白扁豆在本发明制剂中的药理作用主要是抗菌、 抗病毒, 实验表
明: 100%白扁豆煎剂用平板纸片法, 对痢疾杆菌和有抑制作用; 对食 物中毒引起的呕吐、急性胃肠炎等有解毒作用。 白扁豆水提物对小鼠The pharmacological action of white lentils in the preparation of the present invention is mainly antibacterial, antiviral, experimental table Ming: 100% white lentils decoction using plate paper method, has an inhibitory effect on dysentery bacilli; has detoxification effect on vomiting caused by food poisoning, acute gastroenteritis. White lentils water extract against mice
Columbia SK病毒有抑制作用。 The Columbia SK virus has an inhibitory effect.
连翘,味苦,性微寒,是木犀科连翘属植物,连翘早春先叶开花, 花开香气淡艳, 满枝金黄, 艳丽可爱, 是早春优良观花灌木, 果实可 以入药。 连翘主要含苯乙醇苷类、 木脂体及其苷类、 五环三萜娄、 挥 发油类等化合物。 药理研究认为其具有抗菌、 抗炎、 解热、 镇吐、 利 尿强心、 抗肝损、 镇痛、 抑制磷酸二酯酶、 抗病毒、 降血压、 抑制弹 性蛋白酶活力、 抗内毒素等作用。 除果实入药, 具清热解毒、 消结排 脓之效外, 药用其叶, 对治疗高血压、 痢疾、 咽喉痛等效果较好。 连 翘有抗菌、 强心、 利尿、 镇吐等药理作用, 是清热解毒的中药, 主治 热病初起, 风热感冒、 发热、 心烦、 咽喉肿痛、 急性肾炎、 痈肿疮毒 等症状, 其抑菌作用与金银花大体相似。 Forsythia, bitter taste, slightly cold, is the genus Forsythia genus, forsythia early flowering in early spring, flower aroma is light, full of golden, colorful and lovely, is a good early spring flowering shrub, the fruit can be used as medicine. Forsythia mainly contains phenylethanoid glycosides, lignans and their glycosides, pentacyclic triterpenes, and volatile oils. Pharmacological studies believe that it has antibacterial, anti-inflammatory, antipyretic, antiemetic, diuretic, anti-liver, analgesic, inhibition of phosphodiesterase, anti-virus, blood pressure lowering, inhibition of amylase activity, anti-endotoxin and so on. In addition to the fruit into the medicine, with the effect of clearing away heat and detoxifying, eliminating the discharge of pus, the medicinal leaves have better effects on the treatment of hypertension, dysentery and sore throat. Forsythia has antibacterial, cardiotonic, diuretic, antitussive and other pharmacological effects. It is a traditional Chinese medicine for clearing away heat and detoxification. It treats fever, fever, fever, upset, sore throat, acute nephritis, swollen sore and other symptoms. Its antibacterial effect is similar to that of honeysuckle.
茯苓, 茯苓中的主要成分为茯苓聚糖, 含量很高。 对多种细菌有 抑制作用; 能降胃酸, 对消化道溃疡有预防效果; 对肝损伤有明显的 保护作用; 有抗肿瘤的作用; 能多方面对免疫功能进行调节; 能使化 疗所致白细胞减少加速回升; 并有镇静的作用。 茯苓, the main ingredient in sputum is ubiquitin, which is high in content. It has inhibitory effect on various bacteria; it can lower stomach acid and has preventive effect on digestive tract ulcer; It has obvious protective effect on liver injury; It has anti-tumor effect; It can regulate immune function in many aspects; It can make leukocytes caused by chemotherapy Reduce the acceleration and recovery; and have a calming effect.
莱菔子, 性平, 味辛、 甘。 归肺、 脾、 胃经, 主治消食除胀, 降 气化痰。 主治食积气滞, 脘腹胀满, 嗳气, 下痢后重, 咳嗽痰多, 喘 促胸满, 能消食除胀, 功效显著, 有 "冲墙倒壁"之称。 临床习用于 治疗实 (食、 湿、 积滞)证。 然而, 该品并非仅仅是消食除胀, 对虚证 用之, 获效亦佳, 因其性和平, 其气味又不峻, 无偏胜之弊, 不可囿
于 "冲墙倒壁"之说,有破气之嫌 (实则是平气之有余),而弃之不用。 柴胡, 味苦、 辛, 性微寒; 归肝、 胆经; 微香升散; 具有清热解 表、 和解少阳, 疏肝解郁, 升阳举陷的功效, 主治外感发热, 寒热往 来, 疟疾, 黄疸, 胸胁胀痛, 头痛目赤, 耳聋口苦, 月经不调, 脏器 下垂, 脱肛阴挺, 胡能疏肝解郁, 配益气药可升阳举陷, 用于子宫脱 垂、 脱肛, 然无生津解渴之功; 葛根有生津止渴作用, 能生发清阳, 用于水泻, 然无疏肝解郁功能。 Lai Zizi, Shou Ping, Wei Xin, Gan. Return to the lungs, spleen, stomach, attending digestion and dispelling, reducing gas and phlegm. Indications of food stagnation, abdominal fullness, suffocation, squatting and heavy, coughing, panting and chest full, can eliminate digestion, the effect is remarkable, there is the "rushing wall to the wall". Clinically used to treat real (food, wet, stagnation) syndrome. However, this product is not just for digestion and disintegration. It is used for deficiency syndrome. It is also effective. Because of its sexual peace, its smell is not harsh, and there is no disadvantage of winning. In the saying that "the wall is ruined", there is a suspicion of breaking the gas (in fact, it is more than enough), and it is not used. Bupleurum, bitter, spicy, slightly cold; return to the liver, gallbladder; micro-fragrance; with heat-clearing, resolving Shaoyang, soothing liver and relieving depression, the effect of rising sun, attending exogenous fever, cold and heat, Malaria, jaundice, chest pain, headache, red eyes, bitter mouth, bitterness, irregular menstruation, organ drooping, rectal prolapse, Hu Neng Shugan Jieyu, with Yiqi medicine can be raised in the sun, used for uterine off Dangling, rectal prolapse, but no thirst to quench your thirst; Pueraria has a thirst-quenching effect, can produce Qingyang, used for watery diarrhea, but no liver and relief function.
竹茹, 性甘, 微寒, 入肺、 胃、胆经, 主治清热化痰, 除烦止呕。 用于痰热咳嗽, 胆火挟痰, 烦热呕吐, 惊悸失眼, 中风痰迷, 舌强不 语, 胃热呕吐,妊娠恶阻,胎动不安。本品善于涤痰止呕,清热除烦, 适用于痰热咳嗽、 胃热呕哕、 呃逆烦躁等证, 兼可凉血安胎, 用于胎 动不安, 是一味治胃热胃虚呕逆的良药。 Zhuru, sweet, slightly cold, into the lungs, stomach, gallbladder, attending to clear away heat and phlegm, in addition to annoying vomiting. It is used for hot cough, biliary phlegm, irritability, vomiting, convulsions, eye loss, strong tongue, strong tongue, stomach vomiting, pregnancy resistance, fetal movement. This product is good at phlegm and phlegm, clearing away heat and removing troubles. It is suitable for hot cough, stomach heat vomiting, phlegm and irritability, etc. It can also be used for cooling blood and fetus, for fetal movement, and is a cure for stomach heat and stomach vomiting. Good medicine.
肉桂, 可以补元阳, 暖脾胃, 除积冷, 通血脉。 治命门火衰, 肢 冷脉微, 亡阳虚脱, 腹痛泄泻, 寒疝奔豚, 腰膝冷痛, 经闭症瘕, 阴 疽,流注,及虚阳浮越,上热下寒, 肉桂粉温水送服,可治疗胃气胀, 胃寒痛; 将肉桂皮粉末加入菜中烹调, 可有助于控制血糖和胆固醇。 Cinnamon, can make Yuanyang, warm the spleen and stomach, in addition to cold, blood circulation. The rule of life is dying, the limbs are cold, the yang is collapsed, the abdominal pain is diarrhea, the cold sputum is porpoise, the waist and knees are cold and painful, the syndrome is closed, the haze, the flow, and the virtual yang are floating. , Cinnamon powder warm water delivery service, can treat stomach bloating, stomach cold pain; adding cinnamon skin powder to the dish to cook, can help control blood sugar and cholesterol.
砂仁, 味辛, 性温, 归脾经、 胃经、 肾经。 可以化湿开胃, 温脾 止泻,理气安胎,常用于湿浊中阻,脘痞不饥,脾胃虚寒,呕吐泄泻, 妊娠恶阻, 胎动不安。 砂仁善能温中暖胃以达止呕止泻之功, 但其重 在温脾。 Amomum, sin, warm, spleen, stomach, kidney. It can be wet appetizer, warm spleen and diarrhea, qi and amphibious, often used in wet turbidity, hunger, spleen and stomach, vomiting and diarrhea, pregnancy dysfunction, fetal movement. Amomum can warm the stomach to warm up the stomach to relieve vomiting and diarrhea, but it focuses on warming the spleen.
木香, 味辛; 苦; 性温, 归脾; 大肠、三焦经。可以行气, 止痛, 健脾, 消食, 主治行气止痛; 调中导滞。 主胞胁胀满足; 脘腹胀痛;
嗳吐泄泻; 痢疾后重。 用于胸脘胀痛、 泻痢后重、 食积不消、 不思饮 食; 中气不省; 突发耳聋; 蛇虫咬伤; 牙痛。 在中医上作为脾胃气滞 之脘腹胀满或疼痛, 嗳气, 恶心呕吐药。 Woody, Weixin; bitter; warm, spleen; large intestine, three Jiaojing. Can exercise, relieve pain, spleen, digestion, attending to relieve pain; The main cell is swelled and satisfied; Vomiting and diarrhea; heavy after dysentery. For chest pain, heavy after diarrhea, food can not be saved, do not think about diet; middle gas is not; sudden deafness; snake bite; toothache. In Chinese medicine, as a spleen and stomach qi stagnation, abdominal distension or pain, belching, nausea and vomiting.
焦山楂, 是取净山楂, 照清炒法炒至表面焦褐色, 内部黄褐色。 本品形如山楂片, 表面焦褐色, 内部黄褐色。 有焦香气。 味酸、 甘、 微温, 归脾、 胃、 肝经。 可以消食健胃, 行气散瘀。 用于肉食积滞, 胃脘胀满, 泻痢腹痛, 瘀血经闭, 产后瘀阻, 心腹剌痛, 疝气疼痛; 高脂血症。 焦山楂消食导滞作用增强。 用于肉食积滞, 泻痢不爽。 Jiaoshan 楂, is taken from the net hawthorn, fried according to the method of frying until the surface is brown, and the interior is yellowish brown. This product is shaped like a hawthorn slice with a brownish surface and a yellowish interior. There is aroma of coke. Sour, sweet, slightly warm, spleen, stomach, liver. You can digest your stomach and divert your stomach. For meat stagnation, stomach cramps fullness, diarrhea, abdominal pain, blood stasis, postpartum obstruction, heart and abdomen pain, hernia pain; hyperlipidemia. The effect of Jiaoshan 楂 digestion on food is enhanced. It is used for stagnant meat, and it is not good for diarrhea.
炒麦芽, 味甘, 性平。 归脾、 胃经, 用于米面薯蓣食滞证。 本品 能够促进淀粉性食物的消化。 可与焦山楂、 六曲等同用。 若治小儿乳 食停滞, 单用本品煎服或者研末服有效。 若治脾虚食少, 食后饱胀, 可与白扁豆, 陈皮等同用。 Stir-fried malt, sweet, flat. Return to the spleen, stomach, used for rice stagnation. This product can promote the digestion of starchy foods. It can be used in the same way as Jiaoshan and Liuqu. If the child's milk is stagnant, use this product to decoction or the final dress. If the spleen is less expensive, it will be full after eating, and it can be used with white lentils and dried tangerine peel.
黄连可以清热燥湿,泻火解毒。用于湿热痞满,呕吐吞酸,泻痢, 黄疸, 高热神昏, 心火亢盛, 心烦不寐, 血热吐衄, 目赤, 牙痛, 消 渴, 痈肿疔疮; 外治湿疹, 湿疮, 耳道流脓。 酒黄连善清上焦火热。 用于目赤, 口疮。 姜黄连清胃和胃止呕。 用于寒热互结, 湿热中阻, 痞满呕吐。 萸黄连舒肝和胃止呕。 用于肝胃不和, 呕吐吞酸。 本品兼 能疏肝解郁, 用于肝气郁滞或肝胃不和之胁痛、 脘腹痛等, 可与其他 疏肝理气药同用。 Coptis can clear away heat and dampness, purging fire and detoxification. For damp heat, vomiting, vomiting, diarrhea, jaundice, high fever, dizziness, heartburn, upset, bloody vomiting, redness, toothache, thirst, carbuncles and hemorrhoids; external treatment of eczema, Wet sores, pus in the ear canal. Liquor and yellow are good on the fire. For eye red, mouth sores. Turmeric even clears the stomach and stomach to vomit. For cold and heat, heat and humidity, vomiting. Qi Huang Lian Shu liver and stomach to vomit. For liver and stomach disharmony, vomiting and acid. This product can also relieve liver and relieve stagnation, and is used for liver qi stagnation or hypochondriac pain of liver and stomach, abdominal pain, etc. It can be used together with other liver-relieving qi drugs.
薏苡仁, 性凉, 味甘、 淡, 为禾本科植物薏苡的种仁。 有健脾渗 湿, 除痹止泻。 用于水肿、 脚气、 小便不利、 湿痹拘挛、 脾虚泄泻的 功效。功能主治:健脾渗湿, 除痹止泻。用于水肿、脚气、小便不利、
湿痹拘挛、 脾虚泄泻。 Coix seed, cool, sweet, light, is the seed of the grass family. Have spleen and spleen, remove phlegm and diarrhea. It is used for edema, athlete's foot, unfavorable urination, phlegm and blood stasis, spleen deficiency and diarrhea. Indications: spleen and spleen, remove phlegm and diarrhea. For edema, athlete's foot, urinary, Wet sputum, spleen diarrhea.
黄芩, 别名山茶根、 土金茶根。 为唇形科植物, 以根入药。 有清 热燥湿, 凉血安胎, 解毒功效。 主治温热病、 上呼吸道感染、 肺热咳 嗽、 湿热黄胆、 肺炎、 痢疾、 咳血、 目赤、 胎动不安、 高血压、 痈肿 疖疮等症。 黄芩的临床应用抗菌比黄连还好, 而且不产生抗药性。 Astragalus, alias Camellia root, earth tea root. For the plant of the Labiatae, the root is used as a medicine. It has heat and dampness, cool blood and fetus, detoxification effect. Indications for warm disease, upper respiratory tract infection, lung heat cough, damp heat jaundice, pneumonia, dysentery, hemoptysis, red eyes, fetal dysphoria, high blood pressure, bloated hemorrhoids embolism. The clinical application of Astragalus is better than berberine and does not produce drug resistance.
肉苁蓉, 味甘、咸, 性温。归肾、大肠经, 可以补肾阳, 益精血, 润肠通便。 用于阳痿, 不孕, 腰膝酸软, 筋骨无力, 肠燥便秘。 Cistanche, sweet, salty, warm. Return to the kidney, large intestine, can replenish kidney yang, benefit essence blood, run the bowel. For impotence, infertility, weak waist and knees, weak bones, constipation.
白芨, 性寒、 味苦、 甘、 涩, 无毒; 归肺、 胃、 肝经。 具有收敛 止血, 消肿生肌的功能。 主治肺痨略血, 吐血, 衄血, 便血, 外伤出 血, 痈疮肿毒, 瘰疬, 痔漏, 烧烫伤, 手足皲裂, 肛裂等病症。 与本 发明其他中药配伍, 治疗肠炎效果明显。 小米, 是粟 (Setaria ital ica)脱壳制成的粮食, 因其粒小, 直 径 1毫米左右, 故名。 原产于中国北方黄河流域, 中国古代的主要粮 食作物, 所以夏代和商代属于 "粟文化" 。 粟生长耐旱, 品种繁多, 俗称 "粟有五彩" , 小米性凉味甘, 可以止呕消嗳,养肠胃,通便, 止泄,补血益气,健脾,降糖消渴,养阴补虚,对胃肠道有很好的调理和 滋补作用: 主治消化不良: B族维生素可促进消化液分泌, 维持和促 进肠道蠕动,有利于排便。及口角生疮的功效,并且养胃:中和胃酸, 缓解胃痛。 小米具有防止泛胃、 呕吐的功效。 从我国传统中医角度讲, 慢性胃炎的病因病机, 有饮食不节, 戕 伤中州,或外邪内侵,损及脾胃,或忧患郁怒,肝失疏泄,横逆犯胃,
以及禀赋不足, 脾胃虚弱等情形, 其病表在 "胃 " , 但与 "脾" 、 "肝" 、 "肾"却关系密切, 病机特点是虚中夹实, 因此通过本发明 上述中药配伍以及制备方法获得的组合物,采用辩证的方法有效的达 到调理胃与五脏六腑的功效, 无毒副作用, 效果稳定, 与西药相比达 到事半功倍的疗效。 临床实验 1: White peony, cold, bitter, sweet, sputum, non-toxic; return to the lungs, stomach, liver. It has the function of astringent hemostasis, swelling and muscle growth. Indications for pulmonary sputum, blood vomiting, blood stasis, blood in the stool, traumatic bleeding, hemorrhoids, sputum, sputum, burns, hand and foot cleft palate, anal fissure and other diseases. In combination with other traditional Chinese medicines of the invention, the effect of treating enteritis is obvious. Millet, is the grain of the shell of Setaria ital ica, because of its small size, about 1 mm in diameter, hence the name. Originally produced in the Yellow River Basin in northern China, the main food crops in ancient China, so the Xia Dynasty and the Shang Dynasty belonged to the "Sui Culture". Millet is drought-tolerant and has a wide variety. It is commonly known as "Sui You Cai". Xiaomi is cool and sweet. It can stop vomiting, nourish the stomach, laxative, stop venting, nourishing blood and qi, spleen, hypoglycemic and thirst. Tonic, has a good conditioning and nourishing effect on the gastrointestinal tract: Indications of dyspepsia: B vitamins can promote the secretion of digestive juice, maintain and promote intestinal peristalsis, is conducive to bowel movements. And the effect of the mouth sores, and stomach: neutralize stomach acid, relieve stomach pain. Millet has the effect of preventing pancreatic stomach and vomiting. From the perspective of traditional Chinese medicine, the etiology and pathogenesis of chronic gastritis, there are diets, bruises in Zhongzhou, or external evil invasion, damage to the spleen and stomach, or worry about anger, liver loss and diarrhea, cross-counter stomach, Insufficient endowment, spleen and stomach weakness, etc., the disease is in the "stomach", but it is closely related to "spleen", "liver", "kidney", and the pathogenesis is characterized by imaginary inclusion. Therefore, the above traditional Chinese medicine is compatible with the present invention. The composition obtained by the preparation method can effectively achieve the effect of regulating the stomach and the internal organs by using a dialectical method, has no toxic and side effects, and has stable effects, and achieves twice the result with half the effort compared with the western medicine. Clinical Experiment 1:
1 )、观察时间:在本发明技术方案未曾披露的情况下,选择 2013 年 3月到 2013年 8月的 6个月时间。 1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the period of 6 months from March 2013 to August 2013 is selected.
2 )、 观察对象: 在广东省东莞市中医院消化科选择 10例慢性胃 炎病例: 男 6例, 女 4例; 年龄: 40— 55岁 5例, 60— 75岁 5例; 职业: 普通上班族 5例, 退休人员 5例。 病症: 饭后饱胀, 泛酸, 无 规律性腹痛等症状。 2), Observation object: 10 cases of chronic gastritis were selected in the Department of Gastroenterology, Dongguan Hospital of Guangdong Province: 6 males and 4 females; age: 5 cases of 40-55 years old, 5 cases of 60-75 years old; Occupation: General work There are 5 families and 5 retirees. Symptoms: After a meal, fullness, pantothenic acid, no regular abdominal pain and other symptoms.
3 )、 使用方法: 将本发明制剂口服液在餐后半小时服用, 每日 3 次, 每次 200ml, 2个月为 1疗程, 3个疗程作为疗效观察。 3), How to use: The oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.
4 )、 观察效果: 4), observation effect:
在连续服用 3个疗程后, 饭后饱胀, 泛酸, 无规律性腹痛等症状 基本不再出现的 6例, 饭后稍微有饱胀感, 轻微泛酸, 无规律性轻微 腹痛等症状基本不再出现的 2例, 饭后饱胀, 泛酸, 无规律性腹痛改 善不明显的 2例, 总有效率 80%。 After taking 3 courses in a row, 6 cases of symptoms such as fullness after meals, pantothenic acid, irregular abdominal pain, etc., a little fullness after meals, mild pantothenic acid, irregular mild abdominal pain and other symptoms are basically no longer In 2 cases, 2 cases of postprandial fullness, pantothenic acid, and irregular abdominal pain were not obvious, and the total effective rate was 80%.
临床实验 2: Clinical trial 2:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2013
年 4月到 2013年 9月的 6个月时间。 1) Observation time: In the case that the technical solution of the present invention has not been disclosed, select 2013 6 months from April to September 2013.
2 )、 观察对象: 在广东省深圳市南山区沙河医院消化科选择 20 例病例:男 12例,女 8例;年龄: 32—55岁 10例, 56— 75岁 10例; 职业: 曾担任领导岗位公务员 10例, 普通教师 10例。 病症: 上腹部 不适, 疼痛, 消化不良, 呕吐, 呃逆恶心等。 2), Observed: In the Department of Gastroenterology, Shahe Hospital, Nanshan District, Shenzhen City, Guangdong Province, 20 cases were selected: 12 males and 8 females; age: 10 cases of 32-55 years old, 10 cases of 56-75 years old; Occupation: There were 10 civil servants in leadership positions and 10 in general. Symptoms: Upper abdominal discomfort, pain, indigestion, vomiting, disgusting nausea, etc.
3 )、 使用方法: 将本发明制剂口服液在餐后半小时服用, 每日 3 次, 每次 200ml, 2个月为 1疗程, 3个疗程作为疗效观察。 3), How to use: The oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.
4 )、 观察效果: 4), observation effect:
在连续服用 3个疗程后, 病人原先的腹部疼痛, 消化不良已经消 失, 呕吐, 呃逆和恶心等基本不再出现的 12例, 轻微腹部疼痛和消 化不良, 偶尔轻微呕吐, 呃逆和恶心的 3例, 腹部疼痛, 消化不良已 经消失, 呕吐, 呃逆和恶心改善不明显的 5例, 总有效率 75%。 After three consecutive courses of treatment, the patient's original abdominal pain, indigestion has disappeared, vomiting, hiccups and nausea are no longer appearing in 12 cases, mild abdominal pain and indigestion, occasional mild vomiting, hiccups and nausea in 3 cases Abdominal pain, indigestion has disappeared, vomiting, hiccups and nausea improved in 5 cases, the total effective rate is 75%.
临床实验 3: Clinical Trial 3:
1 )、观察时间: 在本发明技术方案未曾披露的情况下, 选择 2013 年 7月到 2013年 12月的 6个月时间。 1) Observation time: In the case where the technical solution of the present invention has not been disclosed, the time period from July 2013 to December 2013 is selected.
2 )、 观察对象: 在广东省深圳市北京大学深圳医院消化科选择 30例病例: 男 12例, 女 18例; 年龄: 35— 55岁 16例, 60— 75岁 14例; 职业: 普通民营企业主 14例, 普通退休教师 16例。 病症: 饭后饱胀, 泛酸, 无规律性腹痛, 上腹部不适, 疼痛, 消化不良, 呕 吐, 呃逆恶心等。 2), Observed: In the Department of Gastroenterology, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, 30 cases were selected: 12 males and 18 females; age: 35-55 years old, 16 cases, 60-75 years old, 14 cases; Occupation: Ordinary private There are 14 business owners and 16 ordinary retired teachers. Symptoms: Postprandial fullness, pantothenic acid, irregular abdominal pain, upper abdominal discomfort, pain, indigestion, vomiting, disgusting nausea, etc.
3 )、 使用方法: 将本发明制剂口服液在餐后半小时服用, 每日 3 次, 每次 200ml, 2个月为 1疗程, 3个疗程作为疗效观察。
4)、 观察效果: 3), How to use: The oral liquid of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for 1 course of treatment, and 3 courses of treatment as therapeutic effects. 4), observation effect:
在连续服用 3个疗程后, 病人原先的腹部疼痛, 消化不良已经消 失, 呕吐, 呃逆和恶心等基本不再出现的 18例, 轻微腹部疼痛和消 化不良, 偶尔轻微呕吐, 呃逆和恶心的 6例, 腹部疼痛, 消化不良, 呕吐, 呃逆和恶心改善不明显的 6例, 总有效率 80%。 结合以上临床数据及本发明的理论依据,可见本发明有益效果在 于,本发明制成的制剂,对于治疗慢性胃炎具有良好效果,而且无毒, 无副作用, 效果稳定, 制取工艺简便易行。 具体实 式 After three consecutive courses of treatment, the patient's original abdominal pain, dyspepsia has disappeared, vomiting, hiccups and nausea are no longer apparent in 18 cases, mild abdominal pain and indigestion, occasional mild vomiting, hiccups and nausea in 6 cases 6 cases of abdominal pain, indigestion, vomiting, hiccup and nausea were not obvious, and the total effective rate was 80%. Combining the above clinical data with the theoretical basis of the present invention, it can be seen that the preparation prepared by the present invention has good effects for treating chronic gastritis, is non-toxic, has no side effects, has stable effects, and is simple and easy to prepare. Specific form
下面结合实施例对本发明详细加以说明: The present invention will be described in detail below with reference to the embodiments:
实施例 1: Example 1:
本发明制剂是由藿香、 六曲、 白扁豆、 连翘、 茯苓、 莱菔子、 柴 胡、 竹茹、 肉桂、 砂仁、 木香、 焦山楂、 炒麦芽、 黄连、 薏苡仁、 黄 芩、 肉苁蓉、 白芨和小米制备成的组合物制剂, 其中各组分的质量配 比为: The preparation of the invention is composed of musk, hexagram, white lentils, forsythia, medlar, lycopene, Bupleurum, Zhuru, cinnamon, Amomum vulgaris, woody, Jiaoshan, fried malt, berberine, coix seed, scutellaria, Cistanche , a preparation of a composition prepared from white peony and millet, wherein the mass ratio of each component is:
藿香 12g 曲 10g 白扁豆 10g 连翘 12g 茯苓 12g 莱菔子 15g 柴胡 10g 竹茹 12g 肉桂 8g Musk 12g 曲 10g white lentils 10g forsythia 12g 茯苓 12g 莱菔子 15g Bupleurum 10g 竹茹 12g Cinnamon 8g
砂仁 15g 木香 15g 焦山楂 13g 炒麦芽 12g 黄连 8g 薏苡仁 10g
黄芩 12g 肉苁蓉 13g 白芨 lOg Amomum 15g Woody 15g Jiaoshanyu 13g Fried Malt 12g Huanglian 8g Coix Seed 10g Astragalus 12g Cistanche 13g White Pelican lOg
小米 16g。 Millet 16g.
上述治疗慢性胃炎中药口服液的制备方法, 包括如下歩骤: The above preparation method for treating a chronic gastritis Chinese medicine oral liquid comprises the following steps:
1 )、将六曲放入小锅进行小炒 2-3分钟, 然后经粉碎机粉碎并过 80目筛, 备用; 1), put the six songs into a small pot for small 2-3 minutes, then crushed by a pulverizer and passed through a 80 mesh sieve, ready for use;
2 )、 将藿香、 白扁豆、 连翘、 茯苓、 柴胡、 竹茹、 肉桂、 小米、 黄芩、 肉苁蓉按比例配好, 经过粉碎机粉碎成粉末并过 90 目筛, 自 然晾干, 备用; 2), the musk, white lentils, forsythia, medlar, Bupleurum, bamboo, cinnamon, millet, scutellaria, cistanche are proportioned, crushed into powder by a pulverizer and passed through a 90 mesh sieve, naturally dried, spare ;
3 )、 将歩骤 1 ) 和 2 ) 中的各组分粉末混合在一起, 加入纯净水 煎煮两次, 第一次加入 8倍纯净水小火煎煮 1小时, 第二次加入 4倍 纯净水小火煎煮半小时, 然后合并煎液并过滤, 备用; 3), mix the powders of each component in steps 1) and 2), add boiling water twice, add 8 times pure water for 1 hour, simmer for 1 hour, and add 4 times for the second time. Decoction in pure water for half an hour, then combine the decoction and filter, set aside;
4 )、 将剩下的莱菔子、 砂仁、 木香、 焦山楂、 炒麦芽、 黄连、 薏 苡仁、 白芨按比例配好, 经过粉碎机粉碎成粉末并过 80 目筛, 自然 晾干, 备用; 4), the remaining Laiwuzi, Amomum villosum L., Muxiang, Jiaoshan, fried malt, berberine, coix seed, and white peony are proportioned well, pulverized into powder after crushing machine and passed through 80 mesh sieve, naturally dried, spare ;
5 )、 将歩骤 4) 中各组分粉末混合在一起, 加入 4〜6倍70%〜80% 的乙醇, 加热回流 3〜5个小时, 提取过滤获得滤液; 然后在剩下的药 渣中再次加入 2〜4倍65%〜75%的乙醇, 加热回流 2〜3个小时, 提取过 滤获得滤液;将两次获得的滤液合并在一起,减压浓缩除去乙醇溶剂, 干燥, 获得干膏; 5), mixing the powders of each component in step 4), adding 4 to 6 times 70%~80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;
6 )、 将上述歩骤 5 ) 中获得的干膏进行超微粉碎成粉末并过 200 目筛, 然后将粉末加入歩骤 3 ) 中的合并煎液, 混合摇匀即可制得。 6), the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to the combined decoction in the step 3), and mixed and shaken to obtain.
制取的上述中药组合物溶液制剂可以用于口服,如果能够早中晚
各饮用一次并长期饮用, 效果更好。 The prepared Chinese medicine composition solution preparation can be used for oral administration, if it can be early, middle and late Drinking once and drinking for a long time, the effect is better.
实施例 2: Example 2:
本发明还可优选的原料质量为 (克): The preferred raw material quality of the present invention is (g):
藿香 12g 六曲 10g 白扁豆 10g 连翘 12g 茯苓 12g 莱菔子 15g 柴胡 10g 竹茹 12g 肉桂 8g 砂仁 15g 木香 10g 焦山楂 13g 炒麦芽 12g 黄连 8g 薏苡仁 10g 黄芩 12g 肉苁蓉 13g 白芨 10g 小米 16g。 Musk 12g Liuqu 10g White lentils 10g Forsythia 12g 茯苓12g Laiwuzi 15g Bupleurum 10g Bamboo Ru 12g Cinnamon 8g Amomum 15g Woody 10g Jiaoshanjing 13g Fried Malt 12g Coptis 8g Coix Seed 10g Astragalus 12g Cistanche 13g White Pelican 10g Millet 16g .
制备方法如实施例 1。 The preparation method is as in Example 1.
实施例 3: Example 3:
本发明还可优选的原料质量为 (克): The preferred raw material quality of the present invention is (g):
藿香 15g 六曲 12g 白扁豆 9g 连翘 15g 茯苓 10g 莱菔子 12g 柴胡 12g 竹茹 10g 肉桂 8g 砂仁 12g 木香 14g 焦山楂 12g 炒麦芽 8g 黄连 8g 薏苡仁 12g 黄芩 10g 肉苁蓉 8g 白芨 10g 小米 15g。 Musk 15g Liuqu 12g White lentils 9g Forsythia 15g 茯苓10g Laiwuzi 12g Bupleurum 12g Bamboo Ru 10g Cinnamon 8g Amomum 12g Woody 14g Jiaoshanyu 12g Fried Malt 8g Coptis 8g Coix Seed 12g Astragalus 10g Cistanche 8g White Pelican 10g Millet 15g .
制备方法如实施例 1 Preparation method as in Example 1
实施例 4;
本发明还可优选的原料质量为 (克): Example 4; The preferred raw material quality of the present invention is (g):
藿香 18g 六曲 15g 白扁豆 12g 连翘 16g 茯苓 12g 莱菔子 15g 柴胡 13g 竹茹 15g 肉桂 12g 砂仁 16g 木香 14g 焦山楂 16g 炒麦芽 10g 黄连 12g 薏苡仁 15g 黄芩 16g 肉苁蓉 13g 白芨 12g 小米 18g。 Musk 18g Liuqu 15g White lentils 12g Forsythia 16g 茯苓12g Laiwuzi 15g Bupleurum 13g Bamboo Ru 15g Cinnamon 12g Amomum 16g Woody 14g Jiaoshanjing 16g Fried Malt 10g Coptis 12g Coix Seed 15g Astragalus 16g Cistanche 13g White Pelican 12g Millet 18g .
制备方法如实施例 1。 The preparation method is as in Example 1.
实施例 5: Example 5
本发明还可优选的原料质量为 (克): The preferred raw material quality of the present invention is (g):
藿香 16g 六曲 18g 白扁豆 15g 连翘 14g 茯芬 15g 莱菔子 18g 柴胡 15g 竹茹 18g 肉桂 14g 砂仁 18g 木香 16g 焦山楂 14g 炒麦芽 12g 黄连 13g 薏苡仁 13g 黄芩 18g 肉苁蓉 15g 白芨 15g 小米 18g。 Musk 16g Liuqu 18g White lentils 15g Forsythia 14g Suifen 15g Laiwuzi 18g Bupleurum 15g Bamboo Ru 18g Cinnamon 14g Amomum 18g Woody 16g Jiaoshanjing 14g Fried Malt 12g Coptis 13g Coix Seed 13g Astragalus 18g Cistanche 15g White Pelican 15g Millet 18g.
制备方法如实施例 1。 The preparation method is as in Example 1.
实施例 6: Example 6:
本发明还可优选的原料质量为 (克): The preferred raw material quality of the present invention is (g):
ί香 log 六曲 18g 白扁豆 15g
15g ;菔子 20g 柴胡 12g 竹茹 20g 肉桂 16g 砂仁 16g 木香 18g 焦山楂 15g 炒麦芽 15g 黄连 15g 薏苡仁 12g 黄芩 16g 肉苁蓉 16g 白芨 13g 小米 20g。 ί香log six songs 18g white lentils 15g 15g; wolfberry 20g Bupleurum 12g bamboo Ru 20g cinnamon 16g Amomum 16g woody 18g Jiaoshan glutinous rice 15g fried malt 15g berberine 15g glutinous rice 12g jaundice 16g Cistanche 16g white peony 13g millet 20g.
制备方法如实施例 1 ( The preparation method is as in Example 1 (
上述实施例仅是本发明众多实施方式的几种,如将各配方按技术方案 中的比例加大或减小药量,制得的这种治疗慢性胃炎制剂疗效并不受 影响, 也将落在本发明的权利保护范围之内
The above embodiments are only a few of the various embodiments of the present invention. For example, if the formula is increased or decreased according to the ratio in the technical solution, the therapeutic effect of the preparation of the chronic gastritis preparation is not affected, and will also fall. Within the scope of the rights of the present invention
Claims
1、 一种治疗慢性胃炎的中药口服液, 其特征在于, 本发明制剂 是由藿香、六曲、 白扁豆、连翘、茯苓、莱菔子、柴胡、竹茹、 肉桂、 砂仁、 木香、 焦山楂、 炒麦芽、 黄连、 薏苡仁、 黄芩、 肉苁蓉、 白芨 和小米制备成的组合物制剂, 其中各组分的质量配比为: 1. A traditional Chinese medicine oral liquid for treating chronic gastritis, characterized in that the preparation of the present invention is composed of Agastache rugosa, Liuqu, white lentil, forsythia suspensa, poria cocos, radish seed, bupleurum, bamboo root, cinnamon, amomum villosum, and wood root. A composition preparation prepared from fragrant, burnt hawthorn, fried malt, coptis, coix seed, scutellaria baicalensis, cistanche deserticola, bletilla striata and millet, in which the mass ratio of each component is:
藿香 12-20g 六曲 10- 22g 白扁豆 8-18g 连翘 10-18g 茯苓 8-15g 莱菔子 Patchouli 12-20g Liuqu 10-22g White lentil 8-18g Forsythia 10-18g Poria 8-15g Rapeseed
10— 20g 10—20g
柴胡 8-16g 茹 12- 20g 8- 16g 砂仁 10-18g 木香 10- 焦山楂 Bupleurum 8-16g Ru 12- 20g 8- 16g Amomum villosum 10-18g Woody 10- Burnt Hawthorn
10— 18g 10—18g
炒麦芽 8-15g 黄连 6-15g 薏苡仁 8-15g 黄芩 10-18g 肉苁蓉 8-16g 白芨 8-15g 小米 10-20g。 Fried malt 8-15g, coptis 6-15g, coix seed 8-15g, skullcap 10-18g, Cistanche deserticola 8-16g, Bletilla 8-15g, millet 10-20g.
2、 根据权利要求 1所述的治疗慢性胃炎的中药口服液, 其特征 还在于, 其中各组分的质量配比为: 2. The traditional Chinese medicine oral liquid for treating chronic gastritis according to claim 1, further characterized in that the mass ratio of each component is:
藿香 12-18g 六曲 10- 18g 白扁豆 8-12g 连翘 12-18g 茯苓 8-12g 莱菔子 Patchouli 12-18g Liuqu 10-18g White lentil 8-12g Forsythia 12-18g Poria 8-12g Rapeseed
10-15g 10-15g
柴胡 8-12g 茹 12- 16g 肉桂 8-12g 砂仁 10-15g 木香 10- 焦山楂 Bupleurum 8-12g Ru 12- 16g Cinnamon 8-12g Amomum villosum 10-15g Woody 10- Burnt Hawthorn
10-15g
炒麦芽 8-12g g 薏苡 ί10-15g Fried malt 8-12g g Coix ί
8-12g 8-12g
黄芩 10-15g 苁蓉 8-12g 白芨 8-12g 小米 12-18g。 Skullcap 10-15g, Cistanche 8-12g, Bletilla 8-12g, millet 12-18g.
3、 根据权利要求 1或 2所述的治疗慢性胃炎的中药口服液, 其 香 15g 六曲 12g 白扁豆 9g 连翘 15g 茯苓 10g 莱菔子 12g 柴胡 12g 竹茹 10g 肉桂 8g 3. The traditional Chinese medicine oral liquid for treating chronic gastritis according to claim 1 or 2, its fragrance is 15g, Liuqu 12g, white lentil 9g, forsythia 15g, poria 10g, radish seed 12g, Bupleurum 12g, bamboo root 10g, cinnamon 8g
砂仁 12g 木香 14g 焦山楂 12g 炒麦芽 8g 黄连 8g 薏苡仁 12g 黄芩 10g 肉苁蓉 8g 白芨 10g Amomum villosum 12g, woody 14g, burnt hawthorn 12g, fried malt 8g, coptis 8g, coix seed 12g, skullcap 10g, Cistanche deserticola 8g, Bletilla 10g
小米 15g。 Xiaomi 15g.
4、 一种治疗慢性胃炎的中药口服液的制备方法, 其特征在于, 其包括如下歩骤: 4. A method for preparing an oral Chinese medicine liquid for treating chronic gastritis, which is characterized in that it includes the following steps:
1 )、将六曲放入小锅进行小炒 2-3分钟, 然后经粉碎机粉碎并过 80目筛, 备用; 1). Put Liuqu into a small pot and stir-fry for 2-3 minutes, then grind it with a grinder and pass it through an 80-mesh sieve, and set aside;
2 )、 将藿香、 白扁豆、 连翘、 茯苓、 柴胡、 竹茹、 肉桂、 小米、 黄芩、 肉苁蓉按比例配好, 经过粉碎机粉碎成粉末并过 90 目筛, 自 然晾干, 备用; 2). Mix the rugosa, white lentil, forsythia, poria, bupleurum, bamboo root, cinnamon, millet, skullcap, and cistanches in proportion, crush it into powder through a pulverizer and pass through a 90-mesh sieve, dry naturally and set aside. ;
3 )、 将歩骤 1 ) 和 2 ) 中的各组分粉末混合在一起, 加入纯净水 煎煮两次,第一次加入 10倍纯净水小火煎煮 1小时,提取滤液备用,
第二次加入 6倍纯净水小火煎煮半小时,然后合并煎液并过滤,备用; 3). Mix the powders of each component in steps 1) and 2) together, add purified water and cook twice. For the first time, add 10 times purified water and cook over low heat for 1 hour. Extract the filtrate and set aside. For the second time, add 6 times purified water and simmer over low heat for half an hour, then combine the decoctions and filter, set aside;
4 )、 将剩下的莱菔子、 砂仁、 木香、 焦山楂、 炒麦芽、 黄连、 薏 苡仁、 白芨按比例配好, 经过粉碎机粉碎成粉末并过 80 目筛, 自然 晾干, 备用; 4). Mix the remaining radish seeds, amomum villosum, woody incense, burnt hawthorn, fried malt, coptis, coix seed, and bletilla striata in proportion. Crush them into powder through a grinder and pass through an 80-mesh sieve. Dry naturally and set aside. ;
5 )、 将歩骤 4 ) 中各组分粉末混合在一起, 加入 4〜6倍70%〜80% 的乙醇, 加热回流 3〜5个小时, 提取过滤获得滤液; 然后在剩下的药 渣中再次加入 2〜4倍65%〜75%的乙醇, 加热回流 2〜3个小时, 提取过 滤获得滤液;将两次获得的滤液合并在一起,减压浓缩除去乙醇溶剂, 干燥, 获得干膏; 5). Mix the powders of each component in step 4) together, add 4 to 6 times of 70% to 80% ethanol, heat and reflux for 3 to 5 hours, extract and filter to obtain the filtrate; then add the remaining medicinal residue. Add 2 to 4 times of 65% to 75% ethanol again, heat and reflux for 2 to 3 hours, extract and filter to obtain the filtrate; combine the two filtrate obtained together, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste ;
6 )、 将上述歩骤 5 ) 中获得的干膏进行超微粉碎成粉末并过 200 目筛, 然后将粉末加入歩骤 3 ) 中的合并煎液, 混合摇匀即可制得。 制取的上述中药组合物溶液制剂可以用于口服,如果能够早中晚各适 量饮用一次并长期饮用, 效果更好。
6). Ultrafinely pulverize the dry paste obtained in the above step 5) into powder and pass it through a 200 mesh sieve. Then add the powder to the combined decoction in step 3), mix and shake well to prepare. The prepared above-mentioned Chinese medicine composition solution preparation can be taken orally. If it can be drunk once in the morning, noon and evening in an appropriate amount and for a long time, the effect will be better.
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CN109169280A (en) * | 2018-09-20 | 2019-01-11 | 四川农业大学 | The preparation method and used medium of coix lacryma-jobi regeneration plant |
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CN101112613A (en) * | 2007-08-07 | 2008-01-30 | 邵明伦 | Medicine for treating cholecystitis, gastritis and hepatitis and method for preparing the same |
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